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[45Ti]Ti-DOTA: En route towards aza-macrocyclic 45Ti-based radiopharmaceuticals
ChemRxiv Pub Date : 2024-04-24 , DOI: 10.26434/chemrxiv-2024-0h8z6-v3
Tamal Roy 1 , Eduard Pogorilyy 1 , Chubina Pathma Kumarananthan 2 , Unni Augestad Kvitastein 2 , Marco Foscato 1 , Karl Wilhelm Törnroos 1 , Tom Christian Holm Adamsen 1, 2 , Erwan Le Roux 1
Affiliation  

We report the first use of DOTA as a chelator for titanium. The resulting complex is fully characterized and extended to the radiolabelling of DOTA with titanium-45.

中文翻译:

[45Ti]Ti-DOTA:开发基于氮杂大环 45Ti 的放射性药物

我们报道了 DOTA 作为钛螯合剂的首次应用。所得复合物得到了充分表征,并扩展到使用钛 45 进行 DOTA 放射性标记。
更新日期:2024-04-24
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