Development of a tear in the abdominal wall allowing for protrusion of intra-abdominal contents is known as a hernia. This can cause pain, discomfort, and may need surgical repair. Hernias can affect people of any age or demographic. In the USA, over 1 million hernia repair procedures are performed each year. During these surgeries, it is common for a mesh to be utilized to strengthen the repair. Different techniques allow for the mesh to be placed in different anatomical planes depending on hernia location and approach. The locations are onlay, inlay, and sublay, with sublay being split into retromuscular or preperitoneal with sublay being the most commonly used. The use of an electrically active hernia repair mesh is of interest to model as electrical stimulation has been shown to improve soft tissue healing which could reduce recurrence rates. Theoretical 3D COMSOL models were built to evaluate the varying electric fields of an electrically active hernia repair mesh at each of the different anatomical planes. Three voltages were chosen (10, 20, and 30 mV) for the study to simulate a low-level electrical signal and the electric field from a piezoelectric material at the tissue layers surrounding the mesh construct. Based on the model outputs, the optimal mesh placement location was the sublay-retromuscular as this location had the highest electric field values in the connective tissues and rectus abdominis muscle, which are the primary tissues of concern for the healing process and a successful repair.

中文翻译：

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不同网片放置平面上电刺激促进疝气修复组织愈合的计算分析

腹壁撕裂导致腹内内容物突出，称为疝气。这可能会导致疼痛、不适，并且可能需要手术修复。疝气可以影响任何年龄或人口的人。在美国，每年进行超过 100 万例疝气修复手术。在这些手术中，通常使用网片来加强修复。根据疝气位置和入路，不同的技术允许将网片放置在不同的解剖平面中。位置有高嵌体、嵌体和垫层，其中垫层分为肌后层和腹膜前层，其中垫层是最常用的。电活性疝修补网的使用对建模很有意义，因为电刺激已被证明可以改善软组织愈合，从而降低复发率。建立理论 3D COMSOL 模型来评估电活性疝修补网在每个不同解剖平面上的变化电场。选择三个电压（10、20 和 30 mV）进行研究，以模拟来自网格结构周围组织层的压电材料的低电平电信号和电场。根据模型输出，最佳网格放置位置是肌下层，因为该位置在结缔组织和腹直肌中具有最高的电场值，而这些组织是愈合过程和成功修复的主要组织。