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A Fluorescent Probe for Hg2+ Specific Recognition Based on Xanthene and its Application in Food Detection and Cell Imaging
Journal of Fluorescence ( IF 2.7 ) Pub Date : 2024-04-23 , DOI: 10.1007/s10895-024-03711-y
Chenglu Zhang , Shiru Nie , Chang Liu , Yang Zhang , Jinghao Guo

The mercury-loving unit aminothiourea was introduced into the xanthene fluorophore to synthesized the probe molecule NXH. NXH has a specific response to Hg2+, and with the addition of (0 ~ 50 µM) Hg2+, the fluorescence intensity of the probe solution was quenched from 2352 a.u. to about 308 a.u. NXH exhibited excellent detection performance of high sensitivity (LOD = 96.3 nM), real-time response (105 s), wide pH range (2.1 ~ 9.3), and strong anti-interference ability for Hg2+. At the same time, NXH has wide range of applications for Hg2+ detection, which can fluorescence imaging of Hg2+ in Hela cells and tea samples, and can also be made into Hg2+ detection test paper.



中文翻译:

基于呫吨的Hg2+特异性识别荧光探针及其在食品检测和细胞成像中的应用

将亲汞单元氨基硫脲引入呫吨荧光团中,合成探针分子NXHNXH对Hg 2+具有特异性响应,随着(0 ~ 50 µM) Hg 2+的添加,探针溶液的荧光强度从2352 au淬灭至约308 au NXH表现出优异的高灵敏度检测性能( LOD = 96.3 nM)、实时响应(105 s)、pH范围宽(2.1 ~ 9.3)、对Hg 2+抗干扰能力强。同时,NXH在Hg 2+检测方面有着广泛的应用,可以对Hela细胞和茶叶样品中的Hg 2+进行荧光成像,也可以制成Hg 2+检测试纸。

更新日期:2024-04-24
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