The development of novel synthetic methods for quaternary ammonium salts is highly demanded since the current synthesis heavily relies on the conventional Menshutkin reaction. Herein, we report photoredox-catalyzed alkylation of α-brominated alkenylammonium salts. Mechanistically, the generation of a highly reactive α-ammoniovinyl radical is the key to our method. This reaction enables the synthesis of various unprecedented α-alkylated alkenylammonium salts.

中文翻译：

---

α-烷基化烯基铵盐的光氧化还原合成

由于目前的合成严重依赖于传统的 Menshutkin 反应，因此迫切需要开发季铵盐的新型合成方法。在此，我们报道了α-溴化烯基铵盐的光氧化还原催化烷基化。从机制上讲，高反应性α-氨基乙烯基自由基的产生是我们方法的关键。该反应能够合成各种前所未有的α-烷基化烯基铵盐。