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Switchable Enantioselectivity in Conjugate Alkyne Addition of β,γ-Unsaturated α-Keto Esters by Asymmetric Binary Acid Catalysis
Organic Letters ( IF 5.2 ) Pub Date : 2024-04-24 , DOI: 10.1021/acs.orglett.4c01101
Depeng Duan 1 , Mengdie Tang 1 , Man Wang 1 , Huixin Qiu 1 , Ran Song 1 , Daoshan Yang 1 , Jian Lv 1
Affiliation  

Switchable enantioselectivity was uncovered in the enantioselective catalytic conjugate addition of β,γ-unsaturated α-keto esters with terminal alkynes to the chiral Lewis acid complex of In(BF4)3 and chiral phosphoric acid.

中文翻译:

不对称二元酸催化 β,γ-不饱和 α-酮酯共轭炔加成中的可切换对映选择性

在将带有末端炔的 β,γ-不饱和 α-酮酯与 In(BF 4 ) 3和手性磷酸的手性路易斯酸络合物进行对映选择性催化共轭加成时,发现了可切换的对映选择性。
更新日期:2024-04-24
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