Introduction Heart failure (HF) incidence is increasing in older adults with high hospitalisation and mortality rates. Treatment is complicated by side effects and comorbidities. We investigated the clinical characteristics of octogenarians presenting to the HF clinic. Methods Data were collected on octogenarians (80–89 years) referred to the HF clinic in two periods. The data included demographics, HF phenotype, comorbidities, symptoms and treatment. We investigate the temporal changes in clinical characteristics using χ2 test. We aimed to determine the clinical characteristics which were associated with optimisation of HF pharmacological intervention in the clinic, conducting multivariate regression analysis. Statistical significance is determined at p<0.05. Results Data were collected in April 2012 to January 2014 and in June 2021 to December 2022. In this cross-sectional study of temporal data, 571 octogenarians were referred to the clinic in the latter period, in whom the prevalence of HF was 68.48% (391 patients). HF with preserved ejection fraction (HFpEF) was the most common phenotype and increased significantly compared with the first period (46.3% and 29.2%, p<0.001). Frailty, chronic kidney disease and ischaemic heart disease increased significantly versus the first period (p<0.001). During the second period, and following the consultation, of the patients with HF with reduced ejection fraction (HFrEF), 86.4% and 82.7% were on a beta blocker and on an ACE inhibitor/angiotensin receptor blocker/angiotensin receptor-neprilysin inhibitor, respectively. Clinical characteristics associated with further optimisations of HF pharmacological therapy in the HF clinic were: New York Heart Association (NYHA) functional class III and the presence of HFrEF phenotype Conclusions With a prevalence of HF at 68% among the octogenarians referred to the HF clinic, HFpEF incidence is rising. The decision to optimise HF pharmacological treatment in octogenarians is driven by NYHA functional class III and the presence of HFrEF phenotype. All data relevant to the study are included in the article or uploaded as supplementary information.

中文翻译：

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到心力衰竭诊断诊所就诊的八旬老人的特征：SHEAF 登记

引言 老年人心力衰竭 (HF) 的发病率不断增加，住院率和死亡率也很高。由于副作用和合并症，治疗变得复杂。我们调查了心力衰竭诊所就诊的八旬老人的临床特征。方法 收集分两个时期转诊至心力衰竭诊所的八旬老人（80-89 岁）的数据。数据包括人口统计、心力衰竭表型、合并症、症状和治疗。我们使用 χ2 检验研究临床特征的时间变化。我们旨在确定与临床中优化心力衰竭药物干预相关的临床特征，进行多变量回归分析。 p<0.05 时确定统计显着性。结果 数据收集时间为2012年4月至2014年1月和2021年6月至2022年12月。在这项时间数据的横断面研究中，后期转诊的80多岁老人有571名，其中心力衰竭患病率为68.48%（ 391 名患者）。射血分数保留的心衰 (HFpEF) 是最常见的表型，与第一期相比显着增加（46.3% 和 29.2%，p<0.001）。与第一阶段相比，虚弱、慢性肾病和缺血性心脏病显着增加（p<0.001）。在第二阶段以及会诊后，射血分数降低的心力衰竭 (HFrEF) 患者中，分别有 86.4% 和 82.7% 正在服用 β 受体阻滞剂和 ACE 抑制剂/血管紧张素受体阻滞剂/血管紧张素受体-脑啡肽酶抑制剂。与 HF 诊所进一步优化 HF 药物治疗相关的临床特征为： 纽约心脏协会 (NYHA) 功能分级 III 和 HFrEF 表型的存在 结论 在转诊至 HF 诊所的八旬老人中，HF 患病率为 68%， HFpEF 发病率正在上升。 NYHA 功能 III 级和 HFrEF 表型的存在推动了优化八旬老人心力衰竭药物治疗的决定。与研究相关的所有数据都包含在文章中或作为补充信息上传。