Antibiotics are extensively utilized in the livestock and poultry industry and can accumulate in animals and the environment, leading to potential health risks for humans via food and water consumption. Research on antibiotic toxicity, particularly their impact as endocrine disruptors on the male reproductive system, is still in its nascent stages. This review highlights the toxic effect of antibiotics on the male reproductive system, detailing the common routes of exposure and the detrimental impact and mechanisms of various antibiotic classes. Additionally, it discusses the protective role of food-derived active substances against the reproductive toxicity induced by antibiotics. This review aims to raise awareness about the reproductive toxicity of antibiotics in males and to outline the challenges that must be addressed in future research.

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抗生素对男性生殖系统影响的研究进展

抗生素广泛应用于畜禽业，可在动物和环境中积累，通过食物和水的消耗对人类造成潜在的健康风险。关于抗生素毒性的研究，特别是其作为内分泌干扰物对男性生殖系统的影响，仍处于起步阶段。这篇综述强调了抗生素对男性生殖系统的毒性作用，详细介绍了常见的接触途径以及各种抗生素类别的有害影响和机制。此外，它还讨论了食品源活性物质对抗生素引起的生殖毒性的保护作用。本综述旨在提高人们对抗生素对男性生殖毒性的认识，并概述未来研究中必须解决的挑战。