Changes of the extracellular milieu could affect cellular crowding. To prevent detrimental effects, cells use adaptation mechanisms to react to such conditions. Using fluorescent crowding sensors, we show that the initial response to osmotic stress is fast but imperfect, while the slow response renders cells more tolerant to stress, particularly in the presence of osmolytes.

中文翻译：

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哺乳动物细胞对渗透压的不完全拥挤适应及其受渗透压调节

细胞外环境的变化可能会影响细胞拥挤。为了防止有害影响，细胞使用适应机制对这种状况做出反应。使用荧光拥挤传感器，我们显示出对渗透压的初始响应是快速但不完善的，而缓慢的响应使细胞更能耐受压力，特别是在存在渗透压的情况下。