Host immune evasion is a key strategy for the continual survival of many microbial pathogens including Apicomplexan protozoan: Plasmodium spp., the causative agent of Malaria. The malaria parasite has evolved a variety of mechanisms to evade the host immune responses within its two hosts: the female Anopheles mosquito vector and vertebrate host. In this review, we will focus on the molecular mechanisms of the immune evasion strategies used by the Plasmodium parasite at the blood stage which is responsible for the clinical manifestations of human malaria. We also aim to provide some insights on the potential targets for malaria interventions through the recent advancement in understanding the molecular biology of the parasite.

中文翻译：

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疟疾血期寄生虫的宿主免疫逃逸策略

宿主逃避免疫是许多微生物病原体（包括Apicomplexan原生动物：疟原虫）的持续存活的关键策略。疟原虫已经进化出多种机制来逃避其两个宿主内的宿主免疫反应：雌性按蚊蚊媒和脊椎动物宿主。在这篇综述中，我们将重点关注疟原虫在血液阶段所使用的免疫逃逸策略的分子机制，该策略负责人类疟疾的临床表现。我们还旨在通过了解寄生虫的分子生物学的最新进展，为疟疾干预的潜在目标提供一些见识。