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FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression Cell Death Dis. (IF 9.0) Pub Date : 2024-04-20 Jie Wu, Ting Wen, Antonio Marzio, Dingli Song, Sisi Chen, Chengcheng Yang, Fengyu Zhao, Boxiang Zhang, Guang Zhao, Alessandra Ferri, Hao Cheng, Jiao Ma, Hong Ren, Qiao Yi Chen, Yiping Yang, Sida Qin
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Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment Cell Death Dis. (IF 9.0) Pub Date : 2024-04-20 Raquel Brañas Casas, Alessandro Zuppardo, Giovanni Risato, Alberto Dinarello, Rudy Celeghin, Camilla Fontana, Eleonora Grelloni, Alexandru Ionut Gilea, Carlo Viscomi, Andrea Rasola, Luisa Dalla Valle, Tiziana Lodi, Enrico Baruffini, Nicola Facchinello, Francesco Argenton, Natascia Tiso
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Cancer-associated fibroblasts secrete FGF5 to inhibit ferroptosis to decrease cisplatin sensitivity in nasopharyngeal carcinoma through binding to FGFR2 Cell Death Dis. (IF 9.0) Pub Date : 2024-04-18 Feng Liu, Ling Tang, Huai Liu, Yanzhu Chen, Tengfei Xiao, Wangning Gu, Hongmin Yang, Hui Wang, Pan Chen
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The role of CXCL2-mediated crosstalk between tumor cells and macrophages in Fusobacterium nucleatum-promoted oral squamous cell carcinoma progression Cell Death Dis. (IF 9.0) Pub Date : 2024-04-18 Fujiao Nie, Jie Zhang, Haoyang Tian, Jingjing Zhao, Pizhang Gong, Huiru Wang, Suli Wang, Pishan Yang, Chengzhe Yang
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Caspase 8 deletion causes infection/inflammation-induced bone marrow failure and MDS-like disease in mice Cell Death Dis. (IF 9.0) Pub Date : 2024-04-18 Shanhui Liu, Kanak Joshi, Lei Zhang, Wenyan Li, Ryan Mack, Austin Runde, Patrick A. Hagen, Kevin Barton, Peter Breslin, Hong-Long Ji, Ameet R. Kini, Zhiping Wang, Jiwang Zhang
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IRE1 signaling increases PERK expression during chronic ER stress Cell Death Dis. (IF 9.0) Pub Date : 2024-04-18 Gideon Ong, Rosemund Ragetli, Katarzyna Mnich, Bradley W. Doble, Wafa Kammouni, Susan E. Logue
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The relationship between the network of non-coding RNAs-molecular targets and N6-methyladenosine modification in tumors of urinary system Cell Death Dis. (IF 9.0) Pub Date : 2024-04-17 Ruiming Li, Chunming Zhu, Yuan Wang, Xia Wang, Yibing Wang, Jiahe Wang, Kefeng Wang
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ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance Cell Death Dis. (IF 9.0) Pub Date : 2024-04-17 Cheol-Jung Lee, Heejung Lee, Seo Ree Kim, Soo-Bin Nam, Ga-Eun Lee, Kyeong Eun Yang, Guk Jin Lee, Sang Hoon Chun, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Sung-Jun Cho, Yong-Yeon Cho
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TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers Cell Death Dis. (IF 9.0) Pub Date : 2024-04-17 Helene Damhofer, Tülin Tatar, Benjamin Southgate, Scott Scarneo, Karl Agger, Daria Shlyueva, Lene Uhrbom, Gillian M. Morrison, Philip F. Hughes, Timothy Haystead, Steven M. Pollard, Kristian Helin
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Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications Cell Death Dis. (IF 9.0) Pub Date : 2024-04-17 Yu-Rui Jiao, Kai-Xuan Chen, Xiang Tang, Yu-Long Tang, Hai-Lin Yang, Yu-Long Yin, Chang-Jun Li
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Mucopolysaccharidosis type II zebrafish model exhibits early impaired proteasomal-mediated degradation of the axon guidance receptor Dcc Cell Death Dis. (IF 9.0) Pub Date : 2024-04-16 Rosa Manzoli, Lorenzo Badenetti, Matteo Bruzzone, Maria Carla Macario, Michela Rubin, Marco Dal Maschio, Antonella Roveri, Enrico Moro
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Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review Cell Death Dis. (IF 9.0) Pub Date : 2024-04-16 Yue Li, Ruishuang Ma, Xia Hao
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Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression Cell Death Dis. (IF 9.0) Pub Date : 2024-04-15 Zhao Cui, Caifeng Li, Wei Liu, Mo Sun, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen
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Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines Cell Death Dis. (IF 9.0) Pub Date : 2024-04-15 Nahide Yildirim, Lakshmi Sarojam, Victoria M. Smith, Nadja M. Pieper, Marius Anders, Ross A. Jackson, Dominik C. Fuhrmann, Vinzenz Särchen, Daniela Brücher, Andreas Weigert, Martin J. S. Dyer, Meike Vogler
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α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway Cell Death Dis. (IF 9.0) Pub Date : 2024-04-13 Marina I. Oliveira da Silva, Miguel Santejo, Isaac W. Babcock, Ana Magalhães, Laurie S. Minamide, Seok-Joon Won, Erika Castillo, Ellen Gerhardt, Christiane Fahlbusch, Raymond A. Swanson, Tiago F. Outeiro, Ricardo Taipa, Michael Ruff, James R. Bamburg, Márcia A. Liz
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STING agonist diABZI enhances the cytotoxicity of T cell towards cancer cells Cell Death Dis. (IF 9.0) Pub Date : 2024-04-13 Ling Wang, Zhaoduan Liang, Yunzhuo Guo, Jean de Dieu Habimana, Yuefei Ren, Obed Boadi Amissah, Omar Mukama, Siqi Peng, Xuanyan Ding, Linshuang Lv, Junyi Li, Min Chen, Zhaoming Liu, Rongqi Huang, Yinchao Zhang, Yi Li, Zhiyuan Li, Yirong Sun
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FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation Cell Death Dis. (IF 9.0) Pub Date : 2024-04-13 Ya Li, Caojian Zuo, Xiaoyu Wu, Yu Ding, Yong Wei, Songwen Chen, Xiaofeng Lu, Juan Xu, Shaowen Liu, Genqing Zhou, Lidong Cai
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Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate Cell Death Dis. (IF 9.0) Pub Date : 2024-04-13 Francesco Marrocco, Elisabetta Falvo, Luciana Mosca, Giada Tisci, Alessandro Arcovito, Alice Reccagni, Cristina Limatola, Roberta Bernardini, Pierpaolo Ceci, Giuseppina D’Alessandro, Gianni Colotti
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The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons Cell Death Dis. (IF 9.0) Pub Date : 2024-04-12 Paul Prunotto, Pauline Marie, Laurent Lebouvier, Yannick Hommet, Denis Vivien, Carine Ali
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ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway Cell Death Dis. (IF 9.0) Pub Date : 2024-04-12 Xiqian Zhou, Junyong Zhao, Tao Yan, Danrong Ye, Yuying Wang, Bai’an Zhou, Diya Liu, Xuehui Wang, Wenfang Zheng, Bowen Zheng, Fengyuan Qian, Yating Li, Dengfeng Li, Lin Fang
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Endothelial DR6 in blood-brain barrier malfunction in Alzheimer’s disease Cell Death Dis. (IF 9.0) Pub Date : 2024-04-12 Xiaomin Huang, Junhua Qi, Yixun Su, Ying Zhou, Qi Wang, Taida Huang, Dongdong Xue, Yunxin Zeng, Alexei Verkhratsky, Benjie Zhou, Hui Chen, Chenju Yi
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PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway Cell Death Dis. (IF 9.0) Pub Date : 2024-04-12 Yuanzhen Ma, Zhiyu Fang, Hongning Zhang, Yijun Qi, Yuke Mao, Junfang Zheng
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RUVBL1 ubiquitination by DTL promotes RUVBL1/2-β-catenin-mediated transcriptional regulation of NHEJ pathway and enhances radiation resistance in breast cancer Cell Death Dis. (IF 9.0) Pub Date : 2024-04-12 Jie Tian, Mingxin Wen, Peng Gao, Maoxiao Feng, Guangwei Wei
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Research progress of post-acute sequelae after SARS-CoV-2 infection Cell Death Dis. (IF 9.0) Pub Date : 2024-04-11 Taiwei Jiao, Yuling Huang, Haiyan Sun, Lina Yang
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Sprouty genes regulate activated fibroblasts in mammary epithelial development and breast cancer Cell Death Dis. (IF 9.0) Pub Date : 2024-04-10 Jiyong Li, Rongze Ma, Xuebing Wang, Yunzhe Lu, Jing Chen, Deyi Feng, Jiecan Zhou, Kun Xia, Ophir Klein, Hao Xie, Pengfei Lu
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Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer Cell Death Dis. (IF 9.0) Pub Date : 2024-04-10 Rhynelle S. Dmello, Michelle Palmieri, Pathum S. Thilakasiri, Larissa Doughty, Tracy L. Nero, Ashleigh R. Poh, Sarah Q. To, Erinna F. Lee, W. Douglas Fairlie, Lisa Mielke, Michael W. Parker, Ivan K. H. Poon, Eduard Batlle, Matthias Ernst, Ashwini L. Chand
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Dietary factors and their influence on immunotherapy strategies in oncology: a comprehensive review Cell Death Dis. (IF 9.0) Pub Date : 2024-04-09 Aleksandra Golonko, Tomasz Pienkowski, Renata Swislocka, Sylwia Orzechowska, Krystian Marszalek, Lukasz Szczerbinski, Artur Hugo Swiergiel, Wlodzimierz Lewandowski
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The requirement of the mitochondrial protein NDUFS8 for angiogenesis Cell Death Dis. (IF 9.0) Pub Date : 2024-04-09 Qian-wei Xiong, Kun Jiang, Xiao-wei Shen, Zhou-rui Ma, Xiang-ming Yan, Hao Xia, Xu Cao
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Transglutaminase 3 regulates cutaneous squamous carcinoma differentiation and inhibits progression via PI3K-AKT signaling pathway-mediated Keratin 14 degradation Cell Death Dis. (IF 9.0) Pub Date : 2024-04-08 Kaili Zhou, Chenglong Wu, Wenjie Cheng, Boyuan Zhang, Ruoqu Wei, Daian Cheng, Yan Li, Yu Cao, Wenqing Zhang, Zhirong Yao, Xue Zhang
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The broad impact of cell death genes on the human disease phenome Cell Death Dis. (IF 9.0) Pub Date : 2024-04-08 Abigail L. Rich, Phillip Lin, Eric R. Gamazon, Sandra S. Zinkel
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Inhibition of acyl-CoA binding protein (ACBP) by means of a GABAARγ2-derived peptide Cell Death Dis. (IF 9.0) Pub Date : 2024-04-06 Gerasimos Anagnostopoulos, Ester Saavedra, Flavia Lambertucci, Omar Motiño, Jordan Dimitrov, David Roiz-Valle, Victor Quesada, Karla Alvarez-Valadez, Hui Chen, Allan Sauvat, Yan Rong, Uxía Nogueira-Recalde, Sijing Li, Léa Montégut, Mojgan Djavaheri-Mergny, Maria Castedo, Carlos Lopez-Otin, Maria Chiara Maiuri, Isabelle Martins, Guido Kroemer
Acyl-CoA binding protein (ACBP) encoded by diazepam binding inhibitor (DBI) is an extracellular inhibitor of autophagy acting on the gamma-aminobutyric acid A receptor (GABAAR) γ2 subunit (GABAARγ2). Here, we show that lipoanabolic diets cause an upregulation of GABAARγ2 protein in liver hepatocytes but not in other major organs. ACBP/DBI inhibition by systemically injected antibodies has been demonstrated
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The dual role of mesenchymal stem cells in apoptosis regulation Cell Death Dis. (IF 9.0) Pub Date : 2024-04-06 Zhuo Chen, Xuewei Xia, Mengwei Yao, Yi Yang, Xiang Ao, Zhaoqi Zhang, Li Guo, Xiang Xu
Mesenchymal stem cells (MSCs) are widely distributed pluripotent stem cells with powerful immunomodulatory capacity. MSCs transplantation therapy (MSCT) is widely used in the fields of tissue regeneration and repair, and treatment of inflammatory diseases. Apoptosis is an important way for tissues to maintain cell renewal, but it also plays an important role in various diseases. And many studies have
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Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy Cell Death Dis. (IF 9.0) Pub Date : 2024-04-04 Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen, Morgan G. Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M. Geertsma, Eric Lian, Nathalie A. Lengacher, Steve M. Callaghan, Alvin Joselin, Julianna J. Tomlinson, Michael G. Schlossmacher, William L. Stanford, Jiyan Ma, Patrik Brundin, Scott D. Ryan, Maxime W. C. Rousseaux
Parkinson’s disease (PD) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (DaNs) and the abnormal accumulation of α-Synuclein (α-Syn) protein. Currently, no treatment can slow nor halt the progression of PD. Multiplications and mutations of the α-Syn gene (SNCA) cause PD-associated syndromes and animal models that overexpress α-Syn replicate several
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The GFPT2-O-GlcNAcylation-YBX1 axis promotes IL-18 secretion to regulate the tumor immune microenvironment in pancreatic cancer Cell Death Dis. (IF 9.0) Pub Date : 2024-04-04 Hui-Ru Zhang, Tian-Jiao Li, Xian-Jun Yu, Chen Liu, Wei-Ding Wu, Long-Yun Ye, Kai-Zhou Jin
The immunosuppressive microenvironment caused by several intrinsic and extrinsic mechanism has brought great challenges to the immunotherapy of pancreatic cancer. We identified GFPT2, the key enzyme in hexosamine biosynthesis pathway (HBP), as an immune-related prognostic gene in pancreatic cancer using transcriptome sequencing and further confirmed that GFPT2 promoted macrophage M2 polarization and
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POLQ inhibition attenuates the stemness and ferroptosis resistance in gastric cancer cells via downregulation of dihydroorotate dehydrogenase Cell Death Dis. (IF 9.0) Pub Date : 2024-04-04 Yanmei Peng, Wenbo Zheng, Yuehong Chen, Xuetao Lei, Zhijing Yang, Yuxuan Yang, Weiqi Liang, Kai Sun, Guoxin Li, Jiang Yu
Gastric cancer (GC) contains subpopulations of cancer stem cells (CSCs), which are described as the main contributors in tumor initiation and metastasis. It is necessary to clarify the molecular mechanism underlying CSCs phenotype and develop novel biomarkers and therapeutic targets for gastric cancer. Here, we show that POLQ positively regulates stem cell-like characteristics of gastric cancer cells
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Ovarian tumor cell-derived JAGGED2 promotes omental metastasis through stimulating the Notch signaling pathway in the mesothelial cells Cell Death Dis. (IF 9.0) Pub Date : 2024-04-04 Syed S. Islam, Falah H. Al-Mohanna, Iman M. Yousef, Ismail A. Al-Badawi, Abdelilah Aboussekhra
The primary site of metastasis for epithelial ovarian cancer (EOC) is the peritoneum, and it occurs through a multistep process that begins with adhesive contacts between cancer cells and mesothelial cells. Despite evidence that Notch signaling has a role in ovarian cancer, it is unclear how exactly it contributes to ovarian cancer omental metastasis, as well as the cellular dynamics and intrinsic
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Orthogonal analysis of mitochondrial function in Parkinson’s disease patients Cell Death Dis. (IF 9.0) Pub Date : 2024-04-03 Sander Barnhoorn, Chiara Milanese, Tracy Li, Lieke Dons, Mehrnaz Ghazvini, Martina Sette, Stefania Farina, Daisy Sproviero, Cesar Payan-Gomez, Pier G. Mastroberardino
The etiopathology of Parkinson’s disease has been associated with mitochondrial defects at genetic, laboratory, epidemiological, and clinical levels. These converging lines of evidence suggest that mitochondrial defects are systemic and causative factors in the pathophysiology of PD, rather than being mere correlates. Understanding mitochondrial biology in PD at a granular level is therefore crucial
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Advances in Engineered Macrophages: A New Frontier in Cancer Immunotherapy Cell Death Dis. (IF 9.0) Pub Date : 2024-04-01 Shuaixi Yang, Yuhang Wang, Jiachi Jia, Yingshuai Fang, Yabing Yang, Weitang Yuan, Junhong Hu
Macrophages, as pivotal cells within the tumour microenvironment, significantly influence the impact of and reactions to treatments for solid tumours. The rapid evolution of bioengineering technology has revealed the vast potential of engineered macrophages in immunotherapy, disease diagnosis, and tissue engineering. Given this landscape, the goal of harnessing and innovating macrophages as a novel
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LIN28B induced PCAT5 promotes endometrial cancer progression and glycolysis via IGF2BP3 deubiquitination Cell Death Dis. (IF 9.0) Pub Date : 2024-04-02 Bin Wang, Bo Wang, Jian Ma, Jun-jian He, Zi-hao Wang, Qing Li, Xiao-xin Ma
Endometrial cancer (EC) cells exhibit abnormal glucose metabolism, characterized by increased aerobic glycolysis and decreased oxidative phosphorylation. Targeting cellular glucose metabolism in these cells could be an effective therapeutic approach for EC. This study aimed to assess the roles of LIN28B, PCAT5, and IGF2BP3 in the glucose metabolism, proliferation, migration, and invasion of EC cells
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TRIB3 promotes the progression of renal cell carcinoma by upregulating the lipid droplet-associated protein PLIN2 Cell Death Dis. (IF 9.0) Pub Date : 2024-04-01 Jun Li, Qian Zhang, Yupeng Guan, Dingzhun Liao, Huikun Chen, Haiyun Xiong, Yiyu Sheng, Xianju Chen, Jun Pang
Abnormal lipid metabolism and lipid accumulation are characteristic hallmarks of renal cell carcinoma (RCC). While there is prior evidence closely linking such lipid accumulation within RCC cells and consequent tumorigenesis, the mechanisms underlying this process remain incompletely understood. In this study, a series of bioinformatics analyses were initially performed by screening RCC databases and
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FOXP3 promote the progression of glioblastoma via inhibiting ferroptosis mediated by linc00857/miR-1290/GPX4 axis Cell Death Dis. (IF 9.0) Pub Date : 2024-04-01 Wenpeng Cao, Ya He, Jinzhi Lan, Shipeng Luo, Baofei Sun, Chaolun Xiao, Wenfeng Yu, Zhirui Zeng, Shan Lei
The oncogenic properties of members belonging to the forkhead box (FOX) family have been extensively documented in different types of cancers. In this study, our objective was to investigate the impact of FOXP3 on glioblastoma multiforme (GBM) cells. By conducting a screen using a small hairpin RNA (shRNA) library, we discovered a significant association between FOXP3 and ferroptosis in GBM cells.
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Targeting RCC1 to block the human soft-tissue sarcoma by disrupting nucleo-cytoplasmic trafficking of Skp2 Cell Death Dis. (IF 9.0) Pub Date : 2024-04-01 Mingzhi Zhuang, Fengyue Li, Hong Liang, Yongfu Su, Lei Cheng, Bingkai Lin, Jun Zhou, Runzhi Deng, Linying Chen, Peng Lyu, Zhonglei Lu
Soft-tissue sarcomas (STS) emerges as formidable challenges in clinics due to the complex genetic heterogeneity, high rates of local recurrence and metastasis. Exploring specific targets and biomarkers would benefit the prognosis and treatment of STS. Here, we identified RCC1, a guanine-nucleotide exchange factor for Ran, as an oncogene and a potential intervention target in STS. Bioinformatics analysis
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LncRNA SNHG26 promotes gastric cancer progression and metastasis by inducing c-Myc protein translation and an energy metabolism positive feedback loop Cell Death Dis. (IF 9.0) Pub Date : 2024-03-29 Zhen-Hua Wu, Yi-Xuan Wang, Jun-Jiao Song, Li-Qin Zhao, Yu-Jia Zhai, Yan-Fang Liu, Wei-Jian Guo
Metastasis is a bottleneck in cancer treatment. Studies have shown the pivotal roles of long noncoding RNAs (lncRNAs) in regulating cancer metastasis; however, our understanding of lncRNAs in gastric cancer (GC) remains limited. RNA-seq was performed on metastasis-inclined GC tissues to uncover metastasis-associated lncRNAs, revealing upregulated small nucleolar RNA host gene 26 (SNHG26) expression
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PQR309, a dual PI3K/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma Cell Death Dis. (IF 9.0) Pub Date : 2024-03-30 Jiaxin Cao, Kangmei Zeng, Qun Chen, Ting Yang, Feiteng Lu, Chaozhuo Lin, Jianhua Zhan, Wenjuan Ma, Ting Zhou, Yan Huang, Fan Luo, Hongyun Zhao
End-stage nasopharyngeal carcinoma (NPC) has unsatisfactory survival. The limited benefit of chemotherapy and the scarcity of targeted drugs are major challenges in NPC. New approaches to treat late-stage NPC are urgently required. In this study, we explored whether the dual PI3K/mTOR inhibitor, PQR309, exerted a favorable antineoplastic effect and sensitized the response to gemcitabine in NPC. We
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Nuclear receptor NURR1 functions to promote stemness and epithelial-mesenchymal transition in prostate cancer via its targeting of Wnt/β-catenin signaling pathway Cell Death Dis. (IF 9.0) Pub Date : 2024-03-26 Xingxing Zhang, Haolong Li, Yuliang Wang, Hui Zhao, Zhu Wang, Franky Leung Chan
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USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway Cell Death Dis. (IF 9.0) Pub Date : 2024-03-26 Anan Li, Shijiang Wang, Jiangbo Nie, Shining Xiao, Xinsheng Xie, Yu Zhang, Weilai Tong, Geliang Yao, Ning Liu, Fan Dan, Zhiguo Shu, Jiaming Liu, Zhili Liu, Feng Yang
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AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis Cell Death Dis. (IF 9.0) Pub Date : 2024-03-23 Bing Deng, Fang Liu, Nana Chen, Xinhao Li, Jie Lei, Ning Chen, Jingjing Wu, Xuan Wang, Jie Lu, Mouxiang Fang, Ailin Chen, Zijian Zhang, Bin He, Min Yan, Yuchen Zhang, Zifeng Wang, Quentin Liu
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Nuclear localization of heparanase 2 (Hpa2) attenuates breast carcinoma growth and metastasis Cell Death Dis. (IF 9.0) Pub Date : 2024-03-22 Maram Hilwi, Katherina Shulman, Inna Naroditsky, Sari Feld, Miriam Gross-Cohen, Ilanit Boyango, Soaad Soboh, Olga Vornicova, Malik Farhoud, Preeti Singh, Gil Bar-Sela, Hadassah Goldberg, Martin Götte, Andrew D. Sharrocks, Yaoyong Li, Ralph D. Sanderson, Neta Ilan, Israel Vlodavsky
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The 10th Barossa meeting: Cell Signalling to Cancer Medicine Cell Death Dis. (IF 9.0) Pub Date : 2024-03-21 Winnie L. Kan, Barbara J. McClure, Christopher N. Hahn, Jason A. Powell
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DMRTA2 supports glioma stem-cell mediated neovascularization in glioblastoma Cell Death Dis. (IF 9.0) Pub Date : 2024-03-20 Marta Maleszewska, Kamil Wojnicki, Jakub Mieczkowski, Sylwia K. Król, Karol Jacek, Magdalena Śmiech, Marta Kocyk, Iwona A. Ciechomska, Mateusz Bujko, Janusz Siedlecki, Katarzyna Kotulska, Wiesława Grajkowska, Małgorzata Zawadzka, Bozena Kaminska
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METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway Cell Death Dis. (IF 9.0) Pub Date : 2024-03-20 Lan Ma, Xi Zhou, Siyue Yao, Xinyu Zhang, Ji Mao, Barbara Vona, Liwen Fan, Shu Lou, Dandan Li, Lin Wang, Yongchu Pan
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The role of RNA-modifying proteins in renal cell carcinoma Cell Death Dis. (IF 9.0) Pub Date : 2024-03-19 Muna A. Alhammadi, Khuloud Bajbouj, Iman M. Talaat, Rifat Hamoudi
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PTEN decreases NR2F1 expression to inhibit ciliogenesis during EGFRL858R-induced lung cancer progression Cell Death Dis. (IF 9.0) Pub Date : 2024-03-18 Thi Thanh Truc Tran, Jan-Jong Hung
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Disrupting pro-survival and inflammatory pathways with dimethyl fumarate sensitizes chronic lymphocytic leukemia to cell death Cell Death Dis. (IF 9.0) Pub Date : 2024-03-18 Maria Elena Mantione, Miriam Meloni, Ilenia Sana, Jessica Bordini, Martina Del Nero, Michela Riba, Pamela Ranghetti, Eleonora Perotta, Paolo Ghia, Lydia Scarfò, Marta Muzio
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Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction Cell Death Dis. (IF 9.0) Pub Date : 2024-03-16 Batuhan Mert Kalkan, Selahattin Can Ozcan, Enes Cicek, Mehmet Gonen, Ceyda Acilan
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Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells Cell Death Dis. (IF 9.0) Pub Date : 2024-03-16 V. E. Hermosilla, L. Gyenis, A. J. Rabalski, M. E. Armijo, P. Sepúlveda, F. Duprat, D. Benítez-Riquelme, F. Fuentes-Villalobos, A. Quiroz, M. I. Hepp, C. Farkas, M. Mastel, I. González-Chavarría, R. Jackstadt, D. W. Litchfield, A. F. Castro, R. Pincheira
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HOXD3 promotes the migration and angiogenesis of hepatocellular carcinoma via modifying hepatocellular carcinoma cells exosome-delivered CCR6 and regulating chromatin conformation of CCL20 Cell Death Dis. (IF 9.0) Pub Date : 2024-03-16 Lumin Wang, Chenyang Qiao, Lili Han, Xiaofei Wang, Jiyu Miao, Li Cao, Chen Huang, Jinhai Wang
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HMGA2 alleviates ferroptosis by promoting GPX4 expression in pancreatic cancer cells Cell Death Dis. (IF 9.0) Pub Date : 2024-03-16 Ziyang Luo, Qingfang Zheng, Shazhou Ye, Yanguo Li, Jiayi Chen, Chengjiang Fan, Jianing Chen, Yuxin Lei, Qi Liao, Yang Xi
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TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer Cell Death Dis. (IF 9.0) Pub Date : 2024-03-15 Fangbin Zhang, Yan Yan, Xinguang Cao, Changqing Guo, Ke Wang, Shuai Lv
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STING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury Cell Death Dis. (IF 9.0) Pub Date : 2024-03-14 Yun Cao, Xinghua Chen, Zijing Zhu, Zilv Luo, Yiqun Hao, Xueyan Yang, Jun Feng, Zongwei Zhang, Jijia Hu, Yonghong Jian, Jiefu Zhu, Wei Liang, Zhaowei Chen