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Myeloperoxidase to high-density lipoprotein ratio: Potential predictor of severity and outcome in patients with acute ischemic stroke Brain Res. (IF 2.9) Pub Date : 2024-03-21 Penghong Li, Cailang Niu, Xueqing Du, Mina Zhao, Haobo Wang, Debo Yang, Yuan Li, Wei Jing
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Neuropsychiatric symptoms profile and markers of Alzheimer disease–type pathology in patients with Lewy body dementias Brain Res. (IF 2.9) Pub Date : 2024-03-21 Chaofan Geng, Leilei Tan, Chen Chen
To determine whether Lewy body dementia (LBD) patients with likely copathology of Alzheimer’s disease (AD) exhibit greater neuropsychiatric symptom (NPS) compared to those without likely AD-type copathology. We enrolled 69 individuals diagnosed with Lewy body dementia (LBD), comprising both dementia with Lewy bodies (DLB) (n = 36) and Parkinson's disease dementia (PDD) (n = 33). These participants
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Towards understanding sex differences in autism spectrum disorders Brain Res. (IF 2.9) Pub Date : 2024-03-19 Karen Q. Leow, Mary A. Tonta, Jing Lu, Harold A. Coleman, Helena C. Parkington
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Variants in 3p24.3 predicts the risk of early neurological deterioration in large artery atherosclerotic stroke Brain Res. (IF 2.9) Pub Date : 2024-03-16 Xiaoya Huang, Qiang Ye, Zhenguo Zhu, Yanyan Chen, Niange Xia, Rongrong Chen, Wujun Geng, Zusen Ye
The rate of early neurological deterioration (END) differs in different subtypes of ischaemic stroke. Previous studies showed gene is a novel susceptibility locus for the occurrence of atherosclerosis and thrombotic events. The objective of this research is to examine the efficacy that may have on the risk of END in large artery atherosclerotic (LAA) stroke. Tagged single nucleotide polymorphisms (SNPs)
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Mu-ERD reflects action understanding, but the effect is small Brain Res. (IF 2.9) Pub Date : 2024-03-16 Lawrence Paul Behmer Jr.
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Adora2A downregulation promotes caffeine neuroprotective effect against LPS-induced neuroinflammation in the hippocampus Brain Res. (IF 2.9) Pub Date : 2024-03-15 Paula Lemes dos Santos Sanna, Liebert Bernardes Carvalho, Camila Cristina dos Santos Afonso, Kassia de Carvalho, Rogério Aires, Jennyffer Souza, Marcel Rodrigues Ferreira, Alexander Birbrair, Maria Martha Bernardi, Alexandra Latini, Rodrigo A. Foganholi da Silva
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The relationship between oxidative stress markers and 1H-Magnetic resonance spectroscopy findings in obsessive compulsive disorder Brain Res. (IF 2.9) Pub Date : 2024-03-15 Fatma Subaşı Turgut, Mahmut Bulut, Salih Hattapoğlu, Mehmet Güneş, Mehmet Cemal Kaya, Faysal Ekici, Mehmet Guli Çetinçakmak, İbrahim Kaplan, Murad Atmaca
The purpose of this study was to examine N-acetyl aspartate (NAA)/creatine (Cr) and glutamate, glutamine, and gamma-aminobutyric acid complex (Glx)/Cr levels in patients with obsessive compulsive disorder (OCD) and healthy controls’ orbitofrontal cortex (OFC) and caudate nucleus (CN) by proton magnetic resonance spectroscopy (1H-MRS) method and to investigate their relationship with oxidative stress
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Poly(rC)-binding protein 1 alleviates neurotoxicity in 6-OHDA-induced SH-SY5Y cells and modulates glial cells in neuroinflammation Brain Res. (IF 2.9) Pub Date : 2024-03-14 Ling-Yun Ma, Bingbing Jia, Haoming Geng, Jiantao Liang, Lirong Huo
Parkinson's disease (PD) is a debilitating neurodegenerative condition characterized by the loss of dopaminergic neurons and neuroinflammation. Previous research has identified the involvement of Poly (rC)-binding protein 1 (PCBP1) in certain degenerative diseases; however, its specific mechanisms in PD remain incompletely understood. In this study, 6-OHDA-induced neurotoxicity in the cell lines SH-SY5Y
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Corrigendum to “Potential biomaterials and experimental animal models for inventing new drug delivery approaches in the neurodegenerative disorder: Multiple sclerosis” [Brain Res. 1822 (2023) 148674] Brain Res. (IF 2.9) Pub Date : 2024-03-14 Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Sruthi Sarvepalli, Chandrakant R. Kokare
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LPCAT3 exacerbates early brain injury and ferroptosis after subarachnoid hemorrhage in rats Brain Res. (IF 2.9) Pub Date : 2024-03-12 Jiahui Hao, Tong Wang, Cheng Cao, Xiang Li, Haiying Li, Heng Gao, Jinquan Li, Haitao Shen, Gang Chen
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Dynamic monitoring of radiation-induced white matter microstructure injury in nasopharyngeal carcinoma via high-angular resolution diffusion imaging Brain Res. (IF 2.9) Pub Date : 2024-03-11 Tiansheng Li, Yihao Guo, Xin Jin, Tao Liu, Gang Wu, Weiyuan Huang, Feng Chen
To investigate white matter microstructural abnormalities caused by radiotherapy in nasopharyngeal carcinoma (NPC) patients using MRI high-angular resolution diffusion imaging (HARDI). We included 127 patients with pathologically confirmed NPC: 36 in the pre-radiotherapy group, 29 in the acute response period (post-RT-AP), 23 in the early delayed period (post-RT-ED) group, and 39 in the late-delayed
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Microstructural abnormality of white matter tracts in rheumatoid arthritis Brain Res. (IF 2.9) Pub Date : 2024-03-11 Zeyu Liu, Bo Hou, Hui You, Chen Yu, Xinping Tian, Mengtao Li, Xiaofeng Zeng, Qian Wang, Feng Feng
Structural and functional brain imaging studies have reported abnormalities of gray matter morphology and functional activities in patients with rheumatoid arthritis (RA). However, it is largely unknown whether patients with RA show alterations of white matter microstructural organization. To automatically identify alteration of white matter microstructure in patients with RA and further examine how
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Ligation of cervical lymphatic vessels decelerates blood clearance and worsens outcomes after experimental subarachnoid hemorrhage Brain Res. (IF 2.9) Pub Date : 2024-03-11 Shi-Qiao Luo, Sheng-Qing Gao, Mao-Xing Fei, Xue-Wang, Yan-Sun, Ran-Zhao, Yan-Ling Han, Han-Dong Wang, Meng-Liang Zhou
Subarachnoid hemorrhage (SAH) is characterized by the extravasation of blood into the subarachnoid space, in which erythrocyte lysis is the primary contributor to cell death and brain injuries. New evidence has indicated that meningeal lymphatic vessels (mLVs) are essential in guiding fluid and macromolecular waste from cerebrospinal fluid (CSF) into deep cervical lymph nodes (dCLNs). However, the
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Symmetric unipedal balance in quiet stance and dynamic tasks in older individuals Brain Res. (IF 2.9) Pub Date : 2024-03-07 Paola Janeiro Valenciano, Victória Emiliano Castan, Pedro Henrique Martins Monteiro, Luis Augusto Teixeira
Previous evidence of increased difference of muscular strength between the dominant and non-dominant legs in older adults suggests the possibility of dissimilar balance control between the legs (between-leg asymmetry) associated with aging. In the current investigation, we evaluated between-leg asymmetries in older adults when performing quiet and dynamic balance tasks. Fifty-two physically active
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Children’s early signs and developmental trajectories of psychotic-like experiences Brain Res. (IF 2.9) Pub Date : 2024-03-06 Luxia Jia, Ziqian Wei, Juan Wang, Xuan Zhang, Huagen Wang, Runsen Chen, Xiaoqian Zhang
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Cerebral endothelial cells mediated enhancement of brain pericyte number and migration in oxygen-glucose deprivation involves the HIF-1α/PDGF-β signaling Brain Res. (IF 2.9) Pub Date : 2024-03-05 Shi-Na Song, Wen-Ping Dong, Xin-Xin Dong, Fang Guo, Lin Ren, Chang-Xin Li, Jian-Ming Wang
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Formononetin alleviates cerebral ischemia-reperfusion injury in rats by targeting the PARP-1/PARG/Iduna signaling pathway Brain Res. (IF 2.9) Pub Date : 2024-03-05 Jie Luo, Youde Cai, Dingling Wei, Liping Cao, Qiansong He, Yuanhua Wu
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Alterations in the spinal cord, trigeminal nerve ganglion, and infraorbital nerve through inducing compression of the dorsal horn region at the upper cervical cord in trigeminal neuralgia Brain Res. (IF 2.9) Pub Date : 2024-03-04 Ülkü Türk Börü, Zülfükar Kadir Sarıtaş, Fatma Görücü Özbek, Cem Bölük, Hakan Acar, Yusuf Koç, Gökçe Zeytin Demiral
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Study on multi-target effects of the novel HDAC6 inhibitor W5 on Aβ/Cu2+-induced Alzheimer's disease model of rats Brain Res. (IF 2.9) Pub Date : 2024-03-03 Ruihua Liu, Linli Guo, Yanan Zhao, Dan Wu, Jiasi Yu, Ping Liu
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Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model Brain Res. (IF 2.9) Pub Date : 2024-03-02 Daymara Mercerón-Martínez, Laura Alacán Ricardo, Arturo Bejerano Pina, Norma Orama Rojo, Ariel Expósito Seco, Yamilé Vega Hurtado, Bárbara Estupiñán Días, Isabel Fernández, Laura García Pupo, Marquiza Sablón Carrazana, Chryslaine Rodríguez-Tanty, Roberto Menéndez Soto del Valle, William Almaguer-Melian
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Effect of high-frequency repetitive transcranial magnetic stimulation on swallowing function and pneumonia in poststroke dysphagia in rats Brain Res. (IF 2.9) Pub Date : 2024-03-01 Jiemei Chen, Fei Zhao, Jiena Hong, Chao Li, Jiantao Zhang, Yilong Shan, Qiuping Ye, Hongmei Wen
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Inosine pretreatment of pregnant rats ameliorates maternal inflammation-mediated hypomyelination in pups via microglia polarization switch Brain Res. (IF 2.9) Pub Date : 2024-03-01 Yong Han, Jinping Sun, Xiaojuan, Ma Xin Li, Quanrui Ma
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Propofol-induced hippocampal Neurotoxicity: A mitochondrial perspective Brain Res. (IF 2.9) Pub Date : 2024-02-29 Moein Ebrahimi, Ali Dabbagh, Firoozeh Madadi
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Chronic pain exacerbates memory impairment and pathology of Aβ and tau by upregulating IL-1β and p-65 signaling in a mouse model of Alzheimer’s disease Brain Res. (IF 2.9) Pub Date : 2024-02-29 Wei Wang, Wen-qing Zheng, Xian Du, Shi-cai Chen, Yan-han Chen, qing-yang Ma, Hao Wang, Shan Gao, Rui Tan, Han-ting Zhang, Yan-meng Zhou, Fang-fang Zhang
Chronic pain is linked to cognitive impairment; however, the underlying mechanisms remain unclear. In the present study, we examined these mechanisms in a well-established mouse model of Alzheimer’s disease (AD). Neuropathic pain was modeled in 5-month-old transgenic APPswe/PS1dE9 (APP/PS1) mice by partial ligation of the sciatic nerve on the left side, and chronic inflammatory pain was modeled in
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The expression of ProBDNF and its high affinity receptor P75NTR in the neurons of emotion-related brain regions of post-stroke depression rats Brain Res. (IF 2.9) Pub Date : 2024-02-27 Xue-Ping Yang, Dan-Dai, Ruo-Xia Chen, Yu-Xuan Li, Xue Rui lv, Yun Li
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Thalamic segmentation based on diffusion tensor imaging in patients with trigeminal neuralgia Brain Res. (IF 2.9) Pub Date : 2024-02-25 Xinyi Li, Hang Zhao, Min Wang, Li Li, Xiulin Wang, Zitang Ma, Hai Du, Rui Li
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Low-frequency rTMS modulated the excitability and high-frequency firing in hippocampal neurons of the Alzheimer’s disease mouse model Brain Res. (IF 2.9) Pub Date : 2024-02-24 Ze Zhang, Chong Ding, Rui Fu, Jiale Wang, Junqiao Zhao, Haijun Zhu
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The use of event-related potentials in the investigation of cognitive performance in people with Multiple Sclerosis: Systematic review Brain Res. (IF 2.9) Pub Date : 2024-02-24 Robin Vlieger, Duncan Austin, Deborah Apthorp, Elena Daskalaki, Artem Lensky, Dianne Walton-Sonda, Hanna Suominen, Christian J. Lueck
A biomarker of cognition in Multiple Sclerosis (MS) that is independent from the response of people with MS (PwMS) to test questions would provide a more holistic assessment of cognitive decline. One suggested method involves event-related potentials (ERPs). This systematic review tried to answer five questions about the use of ERPs in distinguishing PwMS from controls: which stimulus modality, which
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Based on neural network cascade abnormal texture information dissemination of classification of patients with schizophrenia and depression Brain Res. (IF 2.9) Pub Date : 2024-02-24 Linfeng Gan, Linfeng Wang, Hu Liu, Gang Wang
This study used MRI brain image segmentation to identify novel magnetic resonance imaging (MRI) biomarkers to distinguish patients with schizophrenia (SCZ), major depressive disorder (MD), and healthy control (HC). Brain texture measurements, including entropy and contrast, were calculated to capture variability in adjacent MRI voxel intensity. These measures are then applied to group classification
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Silencing of METTL3 inhibits m6A methylation of NEK7 to suppress pyrolysis in an HT-22 cell-based model of intracerebral hemorrhage Brain Res. (IF 2.9) Pub Date : 2024-02-24 Lei Hong, Ting Zhuo, Shuguang Jing
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Structural changes in spinal cord following optic neuritis: Insights from quantitative spinal MRI Brain Res. (IF 2.9) Pub Date : 2024-02-24 Jiyuan Wang, Jing Huang, Zheng Sun, Huiqing Dong, Kuncheng Li, Jie Lu
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Hypothermia promotes tunneling nanotube formation and the transfer of astrocytic mitochondria into oxygen-glucose deprivation/reoxygenation-injured neurons Brain Res. (IF 2.9) Pub Date : 2024-02-23 Xiao-Rui Xi, Zhi-Qiang Zhang, Yan-Li Li, Zheng Liu, Dong-Yang Ma, Zan Gao, Shan Zhang
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Blocking cerebral lymphatic system reduces central and peripheral inflammatory response in ischemic stroke Brain Res. (IF 2.9) Pub Date : 2024-02-23 Lingfei Yang, Qingsheng Li, Kaixin Wang, Huimin Liu, Xuan Yang, Yudi Xu, Yufei Chen, Junfang Teng, Zhe Gong, Yanjie Jia
Reduced blood supply to the brain activates the intracranial inflammatory response, a key contributor to secondary brain damage in ischemic stroke. Post-stroke, activation of peripheral immune cells leads to systemic inflammatory responses. Usingin vivo approaches, we investigated meningeal lymphatics’ role in central immune cell infiltration and peripheral immune cell activation. The bilateral deep
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Research progress on the relationship between epilepsy and circRNA Brain Res. (IF 2.9) Pub Date : 2024-02-23 Jinxia Zhai, Chao Wang, Liang Jin, Mingjie Liu, Yongjun Chen
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Latest advances and clinical application prospects of resveratrol therapy for neurocognitive disorders Brain Res. (IF 2.9) Pub Date : 2024-02-23 Meng-Qin Pei, Li-Ming Xu, Yu-Shen Yang, Wei-Can Chen, Xin-Li Chen, Yu-Ming Fang, Shu Lin, He-Fan He
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Estrogen receptor GPR30 in the anterior cingulate cortex mediates exacerbated neuropathic pain in ovariectomized mice Brain Res. (IF 2.9) Pub Date : 2024-02-23 Jiajia Wang, Shiquan Wang, Zongping Fang, Jianshuai Zhao, Guoqing Zhang, Yaru Guo, Qun Wang, Zhenhua Jiang, Haixing Zhong, Wugang Hou
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The dichotomous activities of microglia: A potential driver for phenotypic heterogeneity in Alzheimer’s disease Brain Res. (IF 2.9) Pub Date : 2024-02-22 Anna Pumo, Samuel Legeay
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The changes of neurogenesis in the hippocampal dentate gyrus of SAMP8 mice and the effects of acupuncture and moxibustion Brain Res. (IF 2.9) Pub Date : 2024-02-21 Xinyuan Liu, Jiangmin Chen, Yanjun Du, Qing Tian, Li Wang, Weixian Li, Guangya Liu, Qian Tan, Jingzhi Wang, Xiaoni Deng
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Brain network analysis of working memory in schizophrenia based on multi graph attention network Brain Res. (IF 2.9) Pub Date : 2024-02-20 Ping Lin, Geng Zhu, Xinyi Xu, Zhen Wang, Xiaoou Li, Bin Li
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Cerebral asymmetry in adult Macaca fascicularis as revealed by voxel-based MRI and DTI analysis Brain Res. (IF 2.9) Pub Date : 2024-02-20 Xinran Chen, Fubing Ouyang, Jiahui Liang, Weixian Huang, Jinsheng Zeng, Shihui Xing
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Modulation of neuronal morphology by antipsychotic drug: Involvement of serotonin receptor 7 Brain Res. (IF 2.9) Pub Date : 2024-02-20 Luisa Speranza, Marta Molinari, Floriana Volpicelli, Enza Lacivita, Marcello Leopoldo, Salvatore Pulcrano, Gian Carlo Bellenchi, Carla Perrone Capano, Marianna Crispino
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Present and Future of Blood-Based Biomarkers of Alzheimer’s Disease: Beyond the Classics Brain Res. (IF 2.9) Pub Date : 2024-02-17 Marina Mantellatto Grigoli, Lucas N.C. Pelegrini, Robert Whelan, Marcia R. Cominetti
The field of blood-based biomarkers for Alzheimer’s disease (AD) has advanced at an incredible pace, especially after the development of sensitive analytic platforms that can facilitate large-scale screening. Such screening will be important when more sophisticated diagnostic methods are scarce and expensive. Thus, blood-based biomarkers can potentially reduce diagnosis inequities among populations
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Classification of self-limited epilepsy with centrotemporal spikes by classical machine learning and deep learning based on electroencephalogram data Brain Res. (IF 2.9) Pub Date : 2024-02-17 Xi Liu, Xinming Zhang, Tao Yu, Ruochen Dang, Jian Li, Bingliang Hu, Quan Wang, Rong Luo
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Atypical cortical hierarchy in Aβ-positive older adults and its reflection in spontaneous speech Brain Res. (IF 2.9) Pub Date : 2024-02-15 Rui He, Jalal Al-Tamimi, Gonzalo Sánchez-Benavides, Guillermo Montaña-Valverde, Juan Domingo Gispert, Oriol Grau-Rivera, Marc Suárez-Calvet, Carolina Minguillon, Karine Fauria, Arcadi Navarro, Wolfram Hinzen
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Effect of heat stress on the hypothalamic expression of water channel- and noncoding RNA biogenesis-related genes in modern broilers and their ancestor red jungle fowl Brain Res. (IF 2.9) Pub Date : 2024-02-15 Elizabeth S. Greene, Travis W. Tabler, Sara K. Orlowski, Sami Dridi
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In vivo mapping of rat brain partial white matter content using hexachlorophene-induced neurotoxicity model Brain Res. (IF 2.9) Pub Date : 2024-02-15 Serguei Liachenko, Sumit Sarkar
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Changes in the expression of satellite glial cell-specific markers during postnatal development of rat sympathetic ganglia Brain Res. (IF 2.9) Pub Date : 2024-02-12 Huu Son Nguyen, Seong Jun Kang, Sohyun Kim, Byung Ho Cha, Kyu-Sang Park, Seong-Woo Jeong
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The neurotransmitter puzzle of Alzheimer's: Dissecting mechanisms and exploring therapeutic horizons Brain Res. (IF 2.9) Pub Date : 2024-02-10 Monika Sharma, Pankaj Pal, Sukesh Kumar Gupta
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EphB3 receptor suppressor invasion, migration and proliferation in glioma by inhibiting EGFR-PI3K/AKT signaling pathway Brain Res. (IF 2.9) Pub Date : 2024-02-08 Zumu Xiao, Shengxuan Huang, Wenjin Qiu, Mengru Pang, Xi Zeng, Xu Xu, Yushi Yang, Binglin Yang, Liangzhao Chu
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BMSCs attenuate radiation-induced brain injury induced hippocampal neuronal apoptosis through a PI3K/Akt/Bax/Bcl-2 signaling pathway Brain Res. (IF 2.9) Pub Date : 2024-02-07 Kaina Xu, Zhanhong Liu, Shichao Pan, Na Zhang, Shuang Wu, Guangrun Yang, Xue Song, Ye Teng, Xu Tong
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Audiogenic kindling activates glutamatergic system in the hippocampus of rats with genetic predisposition to audiogenic seizures Brain Res. (IF 2.9) Pub Date : 2024-02-05 Ekaterina P. Aleksandrova, Andrey P. Ivlev, Alexey A. Kulikov, Alexandra A. Naumova, Margarita V. Glazova, Elena V. Chernigovskaya
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Sex-associated microRNAs potentially implicated in sporadic Alzheimer’s disease (sAD) Brain Res. (IF 2.9) Pub Date : 2024-02-01 Maria Tsamou, Erwin L. Roggen
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Could protein phosphatase 2A and glycogen synthase kinase-3 beta be targeted by natural compounds to ameliorate Alzheimer’s pathologies? Brain Res. (IF 2.9) Pub Date : 2024-02-01 Sushmitaa Dhevii Manoharan, Hafizah Abdul Hamid, Nur Fariesha Md Hashim, Manraj Singh Cheema, Samaila Musa Chiroma, Muzaimi Mustapha, Muhammad Zulfadli Mehat
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Material-common and material-specific neural activity during encoding of words and scenes: A neuroimaging meta-analysis Brain Res. (IF 2.9) Pub Date : 2024-01-30 Hongkeun Kim
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Clinical and cortical trajectories in non-fluent primary progressive aphasia and Alzheimer’s disease: A role for emotion processing Brain Res. (IF 2.9) Pub Date : 2024-01-28 Ramon Landin-Romero, Fiona Kumfor, Austin YS Lee, Cristian Leyton, Olivier Piguet
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High magnitude exposure to repetitive head impacts alters female adolescent brain activity for lower extremity motor control Brain Res. (IF 2.9) Pub Date : 2024-01-24 Taylor M. Zuleger, Alexis B. Slutsky-Ganesh, Dustin R. Grooms, Weihong Yuan, Kim D. Barber Foss, David R. Howell, Gregory D. Myer, Jed A. Diekfuss
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Activation of ChAT+ neuron in dorsal motor vagus (DMV) increases blood glucose through the regulation of hepatic gene expression in mice Brain Res. (IF 2.9) Pub Date : 2024-01-23 Woo-Jin Song, Deok-Hyeon Cheon, HeeIn Song, Daeun Jung, Hae Chan Park, Ju Yeong Hwang, Hyung-Jin Choi, Cherl NamKoong
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Protective effect of scallop-derived plasmalogen against vascular dysfunction, via the pSTAT3/PIM1/NFATc1 axis, in a novel mouse model of Alzheimer’s disease with cerebral hypoperfusion Brain Res. (IF 2.9) Pub Date : 2024-01-23 Yun Zhai, Ryuta Morihara, Tian Feng, Xinran Hu, Yusuke Fukui, Zhihong Bian, Yuting Bian, Haibo Yu, Hongming Sun, Mami Takemoto, Yumiko Nakano, Taijun Yunoki, Ying Tang, Hiroyuki Ishiura, Toru Yamashita
A strong relationship between Alzheimer’s disease (AD) and vascular dysfunction has been the focus of increasing attention in aging societies. In the present study, we examined the long-term effect of scallop-derived plasmalogen (sPlas) on vascular remodeling-related proteins in the brain of an AD with cerebral hypoperfusion (HP) mouse model. We demonstrated, for the first time, that cerebral HP activated