样式: 排序: IF: - GO 导出 标记为已读
-
Resolvin D1 level during different trimesters of pregnancy for predicting the risk of fetal growth retardation in elderly pregnancy Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-04-19 Ying Han, Dandan Wang, Shufang Cai, Lina Zhang, Jingxian Xue
Resolvin D1 (RvD1) is potentially associated with fetal growth retardation (FGR) through alleviating maternal inflammation and its linkage with several pregnancy complications. Thus, this study det...
-
Baseline glycated albumin level and risk of type 2 diabetes mellitus in Healthy individuals: a retrospective longitudinal observation in Korea Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-04-18 Kang-Su Shin, Min-Seung Park, Mi Yeon Lee, Eun Hye Cho, Hee-Yeon Woo, Hyosoon Park, Min-Jung Kwon
Glycated albumin (GA) reflects glycemic status for the past three weeks. GA level demonstrates a strong correlation with HbA1c level and is used as an adjunctive biomarker for diagnosis and monitor...
-
Appearance of hexahydrocannabinols as recreational drugs and implications for cannabis drug testing – focus on HHC, HHC-P, HHC-O and HHC-H Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-04-15 Anders Helander, Malin Johansson, Tomas Villén, Annika Andersson
This study investigated the effects of hexahydrocannabinol (HHC) and other unclassified cannabinoids, which were recently introduced to the recreational drug market, on cannabis drug testing in uri...
-
Establishing a pediatric reference interval for plasma calprotectin Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-04-13 Anne-Birgitte Garm Blavnsfeldt, Tina Parkner, Cindy Soendersoe Knudsen
Plasma calprotectin is a promising new biomarker of inflammatory activity and has been found to correlate well with clinical and endoscopic activity in children and adolescents with inflammatory bo...
-
Circulating microRNA-33b levels are associated with the presence and severity of coronary heart disease Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-04-10 Chen Chen, Qi Liu, Yao Li, Jing-Wen Yu, Shu-Di Wang, Jia-Li Xu, Li Liu
MicroRNA-33b (miR-33b) affected various biological pathways in regulating cholesterol homeostasis which may link to the pathogenesis of atherosclerotic lesions. However, whether this marker is asso...
-
A study of size-selective renal elimination using a novel human model Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-04-08 Johann Sigurjonsson, David Grubb, Anders Grubb, Anders Christensson, Carl M. Öberg, Per Ederoth, Sasha Koul, Matthias Götberg, Troels Yndigegn, Tim Tödt, Benedicte Viterius, Henrik Bjursten
The recently discovered selective glomerular hypofiltration syndromes have increased interest in the actual elimination of molecules in the human kidney. In the present study, a novel human model w...
-
Red blood cell distribution width (RDW) reflects disease severity in patients with carbon monoxide poisoning: systematic literature review and meta-analysis Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-03-28 Giuseppe Lippi, Brandon M. Henry, Camilla Mattiuzzi
No definitive prognostic biomarkers for carbon monoxide (CO) poisoning have been proposed. The aim of this study is to investigate, through a systematic literature review and pooled analysis, wheth...
-
LC-MS/MS analysis of 11-nor-9-carboxy-hexahydrocannabinol (HHC-COOH) and 11-hydroxy-hexahydrocannabinol (HHC-OH) for verification of hexahydrocannabinol (HHC) intake Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-03-26 Paul Pettersson-Pablo, Joakim Oxelbark
Natural and semi-synthetic cannabinoid analogs are getting increasing media attention for their recreative use as an alternative to traditional cannabis, in Sweden as well as internationally. To in...
-
Pediatric reference intervals for serum folate and cobalamin based on a European population without exposure to folic acid fortification Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-03-21 Peter Ridefelt, Johan Saldeen, Mandy Vogel, Uta Ceglarek, Wieland Kiess, Anders Larsson
The aim of the present study was to define pediatric reference intervals for serum cobalamin and folate utilizing data generated from a population not exposed to food fortified with folic acid. Fol...
-
Preinterventional pan-immune-inflammation value as a tool to predict postcontrast acute kidney injury among acute coronary syndrome patients implanted drug-eluting stents: a retrospective observational study Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-03-20 Alparslan Kurtul, Murat Gok
We evaluated the value of pan-immune-inflammation value (PIV) in predicting the risk for postcontrast acute kidney injury (PCAKI), an important complication following percutaneous coronary interven...
-
Five days serum glucose stability at room-temperature in centrifuged fast-clotting serum tubes and the comparability with glucose in heparin-plasma and plasma containing citrate-stabilizer Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-03-07 Hanne Bakkebø, Karen Lund Haaland, Kristin Solli Hoff, Lutz Schwettmann
Glucose measurement plays a central role in the diagnosis of gestational diabetes mellitus (GDM). Because of earlier reports of overestimation of glucose in the widely used tubes containing granula...
-
Reproducibility and stability of the immature platelet fraction using Sysmex XN-10 Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-29 Usman Ali, Gavin Knight, Mridula Chopra, Dimitris A. Tsitsikas
The Immature Platelet Fraction (IPF) is an indicator of thrombopoiesis which is a useful parameter in thrombocytopenia. It demonstrates compensatory mechanisms in production of platelets, but curre...
-
Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-27 Marko Lucijanic, Ivan Krecak, Ena Soric, Anica Sabljic, Tamara Vasilj, David Cicic, Anamarija Vrkljan Vuk, Zvonimir Kremer, Ivo Dilber, Anton Glasnovic, Ozren Jaksic, Rajko Kusec
Secondary polycythemia is commonly observed among patients with chronic pulmonary diseases. However, its significance in the context of Coronavirus disease 2019 (COVID-19) is unknown. We retrospect...
-
Plasma metabolomics for diagnostic biomarkers on ectopic pregnancy Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-25 Ozan Kaplan, Sezin Ertürk Aksakal, Bilge Başak Fidan, Yaprak Engin-Üstün, Mustafa Çelebier
Metabolomics is a relatively novel omics tool to provide potential biomarkers for early diagnosis of the diseases and to insight the pathophysiology not having discussed ever before. In the present...
-
Correction Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-22
Published in Scandinavian Journal of Clinical and Laboratory Investigation (Ahead of Print, 2024)
-
Measurement of plasma total calcium before plasma free ionized calcium – a possibility with affordable pitfalls Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-21 Tobias Skou Kjøller, Bent S. Lind, Peter Schwarz, Henrik L. Jørgensen
Free ionized calcium (fCa) is considered the gold standard for assessing calcium status in patients, but it is relatively expensive and is associated with several preanalytical and analytical error...
-
Reliability of a point of care testing blood gas analyzer for measurement of lactate levels in cerebrospinal fluid Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-20 Alberto Fernández Reina, María Dolores López Abellán, Samir Attaibi Hadri, Ángela Puche Candel, María Isabel Díaz López, Eva Pérez Fernández, Manuel Tomás Orgaz Morales, Luis García de Guadiana-Romualdo
Analysis of cerebrospinal fluid (CSF), including lactate, is key for diagnosis of acute meningitis. Since blood gas analyzers (BGA) enable rapid and safe blood-lactate measurements, we evaluated th...
-
Abbott D-dimer assay: analytical performance and diagnostic accuracy in management of venous thromboembolism Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-16 Ivana Lapić, Anamarija Bogić, Ivana Stojan, Dunja Rogić
This study aimed to assess analytical characteristics and diagnostic accuracy in management of venous thromboembolism (VTE) in the Emergency Department (ED) of the Abbott D-dimer assay applied on t...
-
IgE-kappa multiple myeloma with kappa free light chain: a case report Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-08 Yuyi Hu, Wenqi Shao, Baishen Pan, Beili Wang, Wei Guo
Published in Scandinavian Journal of Clinical and Laboratory Investigation (Vol. 84, No. 1, 2024)
-
Plasma legumain in familial hypercholesterolemia: associations with statin use and cardiovascular risk markers Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-06 Ida Gregersen, Ingunn Narverud, Jacob Juel Christensen, Anders Hovland, Linn K. L. Øyri, Thor Ueland, Kjetil Retterstøl, Martin P. Bogsrud, Pål Aukrust, Bente Halvorsen, Kirsten B. Holven
Legumain is known to be regulated in atherosclerotic disease and may have both pro- and anti-atherogenic properties. The study aimed to explore legumain in individuals with familial hypercholestero...
-
Pre-analytical diagnostic differences despite high adherence to guidelines for gestational diabetes mellitus Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-06 Cathrine Scavenius, Eva Rabing Brix Petersen, Dorte Møller Jensen, Lene Ringholm, Jakoba Sevdal Danielsen, Elisabeth Reinhardt Mathiesen, David McIntyre, Peter Damm, Martin Overgaard, Tine Dalsgaard Clausen
Regional variations in the prevalence of gestational diabetes mellitus (GDM) have been found across Denmark. The objectives of this exploratory survey were to evaluate adherence to the national gui...
-
A case of platelet δ-granule defect identified by decreased CD63 expression and decreased serotonin release measured by flow cytometry and liquid chromatography tandem mass spectrometry Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-02-01 Peter H. Nissen, Torben Stamm Mikkelsen, Carsten Schriver Højskov, Johanne Andersen Højbjerg
Published in Scandinavian Journal of Clinical and Laboratory Investigation (Vol. 84, No. 1, 2024)
-
Correction Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24
Published in Scandinavian Journal of Clinical and Laboratory Investigation (Vol. 83, No. 8, 2023)
-
Duplicate measures of hemoglobin mass within an hour: feasibility, reliability, and comparison of three devices in supine position Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Andreas Breenfeldt Andersen, Thomas Christian Bonne, Nikolai Baastrup Nordsborg, Henrik Holm-Sørensen, Jacob Bejder
Duplicate measure of hemoglobin mass by carbon monoxide (CO)-rebreathing is a logistical challenge as recommendations prompt several hours between measures to minimize CO-accumulation. This study i...
-
Kinetics of insulin and C-peptide and estimation of prehepatic insulin secretion rates after intravenous glucose stimulation using arterial versus venous blood sampling in healthy males Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Emil Brink Wriedt, Urd Kielgast, Maria S. Svane, Søren Møller, Sten Madsbad
An intravenous glucose-infusion of 0.3 g glucose per Kg body weight was administered over 1 min in nine healthy males with simultaneous blood sampling from the hepatic vein, femoral artery and a pe...
-
Dysmagnesemia as a predictor of developing diabetic levels of hemoglobin A1c Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Solav Aziz Ali, Anna Elise Engell, Bent Struer Lind, Henrik Løvendahl Jørgensen
The aim of this study was to assess the possible association between P-Mg and subsequent high levels of HbA1c. The study involves data from primary health care patients and data from patients treat...
-
Reference standard analysis of multiple new and old plasma clearance models and renal clearance with special attention to measurement of reduced glomerular filtration rate Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Carl A. Wesolowski
Nine models were evaluated as candidate glomerular filtration rate (GFR) reference standards in three datasets using [51Cr(EDTA)]– or [169Yb(DTPA)]2− anions in 98 studies. Noncompartmental methods ...
-
Validation of the Hem-Col capillary blood collection system for routine laboratory analyses Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Steef Kurstjens, Marjon J. den Besten, Dorien A. M. van Dartel, Marloes C. C. van Gend, Lizzy Meerts, Rein M. J. Hoedemakers
At home collection of capillary blood using Hem-Col tubes (Labonovum) could offer a solution to patients with chronic conditions, who require frequent laboratory analyses. The collection tubes cont...
-
Serum interα-trypsin inhibitor heavy chain H4 may be an anti-inflammatory marker reflecting disease risk, activity and treatment outcome of ankylosing spondylitis Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Zhumin Sun, Yang Zhang, Haiyan Zhou, Jingyun Li, Yue Zhou, Liyun Wang
Interα-trypsin inhibitor heavy chain H4 (ITIH4) modulates inflammation and immunity, which take part in the pathogenesis of ankylosing spondylitis (AS). The current research intended to discover th...
-
Cystatin C and eGFRCKD-EPI-CysC: novel biomarkers for renal impairment diagnosis and two-year progression-free survival in multiple myeloma Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Jian Niu, Jiajia Yu, Huifang Huang, Jinfang Shi, Dong Zheng, Jun Qiu
To evaluate cystatin C (CysC) and estimation of glomerular filtration rate (GFR) calculated using the formula, CKD-EPI-CysC (eGFRCKD-EPI-CysC) for renal impairment diagnosis and predicting the prog...
-
Vitamin B12 insufficiency and deficiency: a review of nondisease risk factors Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Omar Abuyaman, Ali Abdelfattah, Faten Shehadeh-Tout, Ahmad A. Deeb, Ma’mon M. Hatmal
Vitamin B12 deficiency and insufficiency can lead to both hematological and neurological impairments. This review examines nondisease causes and risk factors associated with dietary availability, s...
-
Quantifying plasma dacarbazine levels in advanced melanoma patients: a liquid chromatography-tandem mass spectrometry performance analysis Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Wenhan Cheng, John Liu, Bryan Jackson
The aim of this study was to develop a robust liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantifying dacarbazine levels in the plasma of advanced melanoma patients, follow...
-
Plasma or serum 5-hydroxyindoleacetic acid can be used interchangeably in patients with neuroendocrine tumours Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Mfon Ewang-Emukowhate, Krithika Subramaniam, Francis Lam, Aimee Hayes, Dalvinder Mandair, Christos Toumpanakis, Ashley Grossman, Devaki Nair, Martyn Caplin
5-hydroxyindole acetic acid, a metabolite of serotonin, is used in the diagnosis and monitoring of patients with neuroendocrine tumours, in particular patients with small intestinal neuroendocrine ...
-
Effects of the presence of fibrin strands on complete blood count parameters Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Marco Rosetti, Melania Olivieri, Valentina Polli, Evita Massari, Marta Monti, Alice Clementoni, Virginia Libri, Giovanni Poletti, Tommaso Fasano
Published in Scandinavian Journal of Clinical and Laboratory Investigation (Vol. 83, No. 8, 2023)
-
Stability of potassium, calcium and phosphorus electrolytes in three different tubes in patients with essential thrombocytosis Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Murat Aksit, Merve Zeytinli Aksit, Ayfer Colak, Banu Isbilen Basok, Cengiz Ceylan
Proper blood collection and timely analysis are vital steps for reliable results. This study aims to compare potassium(K), calcium(Ca), and phosphorus(P) concentrations in serum separator tube (SST...
-
Evaluation of the Premier Hb9210 instrument for HbA1c determination Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 David Núñez-Jurado, Jorge Montenegro-Martínez, Ricardo Rubio-Sánchez, Manuel Conde-Sánchez, Inmaculada Domínguez-Pascual
Background: Glycated hemoglobin measurements are a valuable tool for long-term blood glucose monitoring and the diagnosis of diabetes. Its widespread use has been made possible due to the developme...
-
Effect of physical exercise in people with hypothyroidism: systematic review and meta-analysis Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-24 Iratxe Duñabeitia, Daniel González-Devesa, Silvia Varela-Martínez, Jose Carlos Diz-Gómez, Carlos Ayán-Pérez
This study aimed to systematically revise the available evidence on the effects of physical exercise training programmes on people with hypothyroidism. Comparative studies were searched in six elec...
-
Analysis of HbA1c using microfluidic card (Capitainer qDBS card) as a pre-step before determination of the HbA1c value with an immunological method Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2024-01-19 Niclas Rollborn, Anders Larsson, Kim Kultima
The objective of the study was to evaluate Capitainer’s quantitative dried blood spots (qDBS) card for Hemoglobin A1c (HbA1c) testing. qDBS cards can be used for at-home sampling for HbA1c determin...
-
Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-12-21 Christine Rasmussen, Michael M. Richter, Nicole J. Jensen, Niklas Heinz, Bolette Hartmann, Jens J. Holst, Sasha A. S. Kjeldsen, Nicolai J. Wewer Albrechtsen
Plasma concentrations of glucagon, GLP-1 and GIP are reported in numerous clinical trials as outcome measures but preanalytical guidelines are lacking. We addressed the impact of commonly used bloo...
-
Low pregnancy-specific beta-1-glycoprotein is associated with nondipper hypertension and increased risk of preeclampsia in pregnant women with newly diagnosed chronic hypertension Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Kenan Toprak, Zafer Yıldız, Selim Akdemir, Kamil Esen, Rahime Kada, Nuran Can Güleç, Bahadır Omar, Asuman Biçer, Recep Demirbağ
Chronic hypertension is one of the major risk factors for preeclampsia. Pregnancy-specific beta-1-glycoprotein (PSG-1) is a protein that plays a critical role in fetomaternal immune modulation and ...
-
Establishment of a reference interval for glycated albumin based on medical check-up data from multiple medical institutions Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Masafumi Koga, Ikki Shimizu, Yasuko Nakamura, Minoru Yamakado
Objectives: Data were collected to establish a reference interval for glycated albumin (GA), as well as to calculate a cutoff value for diagnosing diabetes mellitus and the GA level corresponding t...
-
The LEAP checklist for Laboratory Evaluation and Analytical Performance Characteristics reporting of clinical measurement procedures Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Tze Ping Loh, Brian R. Cooke, Thi Chi Mai Tran, Corey Markus, Rosita Zakaria, Chung Shun Ho, Elvar Theodorsson, Ronda F. Greaves
Reporting a measurement procedure and its analytical performance following method evaluation in a peer-reviewed journal is an important means for clinical laboratory practitioners to share their fi...
-
Assessing IgE sensitization profiles to birch and timothy grass pollen allergens in birch pollen allergic blood donors using an oligoplex specific IgE assay Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Faiza Mahmood, Lise Sofie Haug Nissen-Meyer, Geir Hetland, Ivo Nentwich
IgE sensitization profiles to single birch allergens in birch-sensitized patients differ among European countries. The aim of this study was to determine the distribution of specific IgE antibodies...
-
A survey of total IgE reference intervals reported by Scandinavian and British medical laboratories – a need for harmonisation Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Erik Wilhelm Vinnes, Ida Sofie Karlsen Sletten, Marie Alnæs, Torgeir Storaas, Aasne K. Aarsand
There appears to be marked discrepancies between total IgE reference intervals (RIs) in use by many laboratories and those recommended by published studies. The aim of this study was therefore to r...
-
Plasma N-terminal pro-B-type natriuretic peptide in the detection of aortic valve stenosis Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Elisa Koljonen, Laura Lappalainen, Sanna Kotiranta, Anu Turpeinen, Ville Vepsäläinen, Satu Kärkkäinen, Jarkko Romppanen, Tuomas Selander, Juha Hartikainen, Jaana Rysä
Systolic murmur suggestive of aortic valve origin is a common accidental finding, particularly in the elderly. Usually, it is due to aortic stenosis (AS) or aortic sclerosis (ASc). Currently, echoc...
-
Direct cord blood LAMP colorimetric phenol red assay for detecting α0-thalassemia (SEA deletion); the validation and post-natal screening in Thailand Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Rossarin Karnpean, Amarin Narkwichean, Wipada Laosooksathit, Prapaporn Panichchob, Wittaya Jomoui
Post-natal or newborn screening for thalassemia and hemoglobinopathies is useful for genetic counseling and managing thalassemia in children. We characterized thalassemia genotypes in newborns from...
-
Subclinical hypothyroidism in pregnancy – assessment of offspring thyroid status and mitochondrial robustness to stress Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Julie Kristine Guldberg Stryhn, Jacob Larsen, Palle Lyngsie Pedersen, Peter Haulund Gæde
Subclinical hypothyroidism’s clinical implications on pregnancy are controversial. Consequently, thyrotropin (TSH) cutoff-values for pregnancy are continuously a subject for debate. In subclinical ...
-
Biological variation of plasma 25-Hydroxyvitamin D3, Serum vitamin B12, folate and ferritin in Turkish healthy subject Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30 Hayat Ozkanay, Fatma Demet Arslan, Figen Narin, Mehmet Hicri Koseoglu
Biological variation (BV) plays a crucial role in determining analytical performance specifications, assessing serial measurements of individuals, and establishing the use of population-based refer...
-
Correction Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-11-30
Published in Scandinavian Journal of Clinical and Laboratory Investigation (Vol. 83, No. 7, 2023)
-
White matter hyperintensities combined with serum NLRP3 in diagnosis of cognitive impairment in patients with cerebral small vessel disease Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-13 Ronghui Huang, Lin Zhang, Limeng Deng, Can Chen
Background: White matter hyperintensities (WMH) are widely used for the diagnosis of cerebral small vessel disease (CSVD). However, whether NLRP3 is correlated with cognitive impairment after CSVD ...
-
The C-reactive protein Albumin ratio was not consistently associated with cardiovascular and all-cause mortality in two community-based cohorts of 70-year-olds Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-13 Per Wändell, Axel Carl Carlsson, Anders Larsson, Johan Ärnlöv, Tobias Feldreich, Toralph Ruge
C-reactive protein (CRP)/Albumin ratio (CAR) seems to mirror disease severity and prognosis in several acute disorders particularly in elderly patients, which we aimed to study. As method we use a ...
-
The free cortisol calculated: correlation with the free cortisol concentrations measured with liquid chromatography-tandem mass spectrometry after equilibrium dialysis and establishment of reference intervals Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-13 Fleur Wolff, Ken Geivaerts, Elise Mathieu, Cécile Duterme, Guillaume Deprez, David Fage, Frédéric Cotton
Changes in cortisol binding globulin (CBG) impact the total serum cortisol concentration and affect the accurate assessment of adrenal function. Free biologically cortisol can be calculated using d...
-
The alcohol biomarker phosphatidylethanol (PEth) – test performance and experiences from routine analysis and external quality assessment Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-12 Anders Helander, Therese Hansson
Phosphatidylethanol (PEth) are membrane molecules formed from phosphatidylcholine and ethanol through transphosphatidylation catalyzed by phospholipase D. Measurement of the main PEth form 16:0/18:...
-
The performance of saliva test strips for determining ethanol levels, as compared to gas chromatography and breathalyser methods Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-11 Niklas Wargh, Juha Piltti, Pirjo Hedberg
We set out to determine the performance of the Testi Technologies enzymatic assay saliva ethanol test strips of three different detection levels: 0 g/L, 0.2 g/L and 0.5 g/L, using as the reference ...
-
Verifying measurements on Siemens Atellica® instruments using clinically acceptable analytical performance specifications Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-06 Emmi Rotgers, Tea Lamberg, Tero Pihlajamaa, Christel Pussinen, Lotta Joutsi-Korhonen, Timo T. Kouri
Measurements on clinical chemistry analysers must be verified to demonstrate applicability to their intended clinical use. We verified the performance of measurements on the Siemens Atellica® Solut...
-
General practitioners’ assessment of interventions applied to optimize laboratory test utilization: a cross-sectional survey study Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-09-01 Serena Lillo, Trine Rennebod Larsen, Kirsten Ohm Kyvik, Jens Søndergaard, Steen Antonsen
General practitioners (GPs) in the Region of Southern Denmark were randomly allocated to a range of interventions to optimize their use of Vitamin D tests over one year. The aim of the current surv...
-
Neurofilament light chain: serum reference intervals in Danish children aged 0-17 years Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-08-26 Mia Elbek Schjørring, Tina Parkner, Cindy Soendersoe Knudsen, Lea Tybirk, Claus Vinter Bødker Hviid
Elevated levels of neurofilament light chain (NfL) in the blood is an unspecific biomarker for damage to neuronal axons. The measurement of NfL levels in the blood can provide useful information fo...
-
Myocardial injury after non-cardiac surgery and per operative fibrin metabolism in patients undergoing hip-fracture surgery: an observational study Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-08-16 Kirsten L. Wahlstrøm, Sarah Ekeloef, Ismail Gögenur, Anna-Marie B. Münster
Abstract Myocardial injury after non-cardiac surgery (MINS) is associated with a 2-3-fold increased risk of subsequent major cardiovascular events and postoperative mortality. The pathological mechanism behind MINS is not fully uncovered. We hypothesized that patients with MINS following hip fracture surgery would have an altered haemostatic balance pre- and postoperative compared with patients without
-
Hypoosmolar and hyperosmolar COVID-19 patients are predisposed to dismal clinical outcomes Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-08-02 Marko Lucijanic, Ivan Krecak, David Cicic, Marko Milosevic, Damir Vukoja, Ivona Kovacevic, Ivan Marasovic, Martina Sedinic Lacko, Josip Bakovic, Zeljko Jonjic, Tamara Vasilj, Josip Stojic, Armin Atic
We aimed to investigate the associations of hypo- and hyperosmolarity at hospital admission with clinical characteristics and outcomes in 5645 consecutive hospitalized COVID-19 patients treated at ...
-
Reference change values of FIB-4 Scand. J. Clin. Lab. Invest. (IF 2.1) Pub Date : 2023-07-28 Arne Åsberg, Lena Løfblad, Gunhild Garmo Hov, Gustav Mikkelsen
When comparing two analytical results for the same analyte, the clinicians may benefit from knowing the reference change values (RCVs) of the analyte. For Fibrosis-4 Index (FIB-4), a noninvasive te...