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Impact of consumption of the human milk oligosaccharides 2′-FL and LNnT on reduction of risk of allergic sensitisation Food Agric. Immunol. (IF 3.0) Pub Date : 2024-02-29 Sébastien Holvoet, Francis Foata, Sophie Nutten, Ellen Ní Cléirigh, Maya Shevlyakova, Cheong Kwong Chung, Gregory Lefevre, Norbert Sprenger, Tristan Bourdeau, Dominique Donnicola, Mario Noti, Severine Combremont, Aristea Binia, Chiara Nembrini, Mandy Vogel, Wieland Kiess, Carine Blanchard
Human Milk Oligosaccharides (HMOs) have been proposed to be instrumental in building immune competence. To explore the role of HMOs in allergy prevention, twenty-one HMOs were quantified in breast ...
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Production of monoclonal antibody and development of an icELISA for the detection of paxilline in grain Food Agric. Immunol. (IF 3.0) Pub Date : 2024-01-28 Jiaxin Wang, Wenhua Shang, Shibei Shao, Jialin Zhang, Qiuyang Wu, Min He, Licai Ma, Jianzhong Shen, Zhanhui Wang, Kai Wen
Paxilline (PAX) is a tremorgenic mycotoxin that is thought to be associated with various syndromes in animals. To facilitate the determination of this toxin, a hapten was chemically synthesized and...
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Genome-wide identification, evolutionary analysis of 4CL gene family and expression analysis in banana Food Agric. Immunol. (IF 3.0) Pub Date : 2023-12-30 Mengge Wang, Liang Jia, Yanying Liu, Chunyu Zhang, Yukun Chen, Yuling Lin, Yuji Huang, Zhongxiong Lai
4-coumaric acid coenzyme A ligase (4CL) plays an important role in plant growth, development and resistance. Based on the Musa acuminata (A genome) genome database, we performed genome-wide identif...
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Integrated double signal amplification systems with ELISA assay for sensitive detection of tylosin in food Food Agric. Immunol. (IF 3.0) Pub Date : 2023-12-22 Shan Shan, Xi Lv, Xiaoyue Xiao, Yanmei Huang, Xiaoyu Tong, Weihua Lai, Chengwei Liu, Shuanglong Wang, Daofeng Liu
Tylosin (TYL) is a kind of antibiotics which promotes the development of animal husbandry, but it poses potential threats to food safety and human health. Therefore, it is necessary to establish a ...
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Analysis of quality and antibiotic residues in raw milk marketed informally in the Province of Pichincha – Ecuador Food Agric. Immunol. (IF 3.0) Pub Date : 2023-12-17 Byron Puga-Torres, Eduardo Aragón, Andrés Contreras, Dayanna Escobar, Karina Guevara, Lizeth Herrera, Nicolás López, Diana Luje, Michelle Martínez, Lenin Sánchez, Debora Tapia, Tania Villarreal, Luis Núñez
In Ecuador, more than 50% of the milk produced was informally marketed, consequently, the mean of this study was to assess the quality of this milk specifically within the province of Pichincha, th...
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Curcumin: a bioactive compound with molecular targets for human malignancies Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-29 Muhammad Shahbaz, Muhammad Imran, Muzzamal Hussain, Suliman A. Alsagaby, Ushna Momal, Hammad Naeem, Mohamed A. Abdelgawad, Ahmed H. El-Ghorab, Waleed Al Abdulmonem, Ahmed Bilal Waqar, Mohammed M. Ghoneim, Arafa Musa, Entessar Al Jbawi
Cancer is the second leading cause of death in the world and one of the major public health problems. Curcumin has anticancer activity including inducing apoptosis and inhibiting proliferation and ...
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Anti-inflammatory effect of Dieffenbachia standleyi Croat extract on lipopolysaccharide-stimulated murine macrophages Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-29 Hyunjun Jang, Wan-Hoon Kim, Bo Kyeong Kim, Ki-Uk Kim, Jisu Kim, Kang Bin Dan, Eunsu Lim, Indiana Maria Coronado, Dong-Keun Yi, Hyeyoung Min
Dieffenbachia standleyi Croat is a plant belonging to Araceae and is native to Central America, and South America. While there have been studies on the Dieffenbachia species, Dieffenbachia standley...
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Correction Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-28
Published in Food and Agricultural Immunology (Vol. 34, No. 1, 2023)
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Potential effect of kaempferol against various malignancies: recent advances and perspectives Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-27 Muhammad Shahbaz, Muhammad Imran, Ushna Momal, Hammad Naeem, Suliman A. Alsagaby, Waleed Al Abdulmonem, Ahmed H. El-Ghorab, Mohammed M. Ghoneim, Muzzamal Hussain, Mohamed E. Shaker, Mohamed A. Abdelgawad, Ahmed Mujtaba, Entessar Al Jbawi
Kaempferol is a flavonoid present in many eatable plants. Researchers discovered a link between consuming foods high in kaempferol and lowering the threat for acquiring many diseases, including car...
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Protective effects of an aqueous extract of Protaetia brevitarsis seulensis larvae in an ovalbumin-induced murine model of asthma Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-22 Hyun-Yong Kim, Hyeon-Hwa Nam, Young Hye Seo, Sueun Lee, Jin Mi Chun, Jun Lee, Jun Ho Song, Kon-Young Ji, Sung-Wook Chae, Bohye Kim, Changjong Moon, Yun-Soo Seo, Joong-Sun Kim
Asthma is a disease-related allergic response characterized by the accumulation of inflammatory cells in airway tissue. Protaetia brevitarsis seulensis larvae are known for their nutritional value ...
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Overdose intake of Neu5Gc triggers colorectal inflammation and alters liver metabolism Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-22 Teng Yuan, Peidong Yang, Anjing Zhang, Jing Li, Ziyin Han, Shuqi Yang, Yihamu Jimu, Fanli Kong, Dengke Pan, Keren Long, Mingzhou Li, Lu Lu
A positive correlation between massive red meat consumption with colorectal cancer had been reported. Given the complexity of meat components, we focused on investigating the role of Neu5Gc in huma...
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Untargeted metabolomics revealed the product formation rules of two fermented walnut milk Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-22 Wangrui Li, Tongxin Zhi, Siting Li, Junxia Xia, Yiling Tian, Aijin Ma, Yingmin Jia
This study employed untargeted metabolomics to reveal the changes in the metabolic profile of walnut milk under two different processing methods. The walnut milk of the control group was not treate...
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The enhancement of bioactive phytochemicals in agarwood leaves by post-harvest application using yeast extract elicitors and evaluation of their bioactivities Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-08 Rattanathorn Choonong, Jakkrit Jabsanthia, Varinda Waewaram, Khunkhang Butdapheng, Boonchoo Sritularak, Waraporn Putalun
Agarwood (Aquilaria crassna) leaves are commonly used as an herbal tea for health supplements. The present study aims to develop the post-harvest process of agarwood leaves using yeast extract (YE)...
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Anti-cancer perspectives of resveratrol: a comprehensive review Food Agric. Immunol. (IF 3.0) Pub Date : 2023-11-08 Muhammad Junaid Anwar, Areeba Altaf, Muhammad Imran, Muhammad Amir, Suliman A. Alsagaby, Waleed Al Abdulmonem, Ahmed Mujtaba, Ahmed H. El-Ghorab, Mohammed M. Ghoneim, Muzzamal Hussain, Entessar Al Jbawi, Mohamed E. Shaker, Mohamed A. Abdelgawad
Resveratrol (RVT) is well known for its chemo-preventive and therapeutic attributes against the various kinds of cancers such as breast, prostate, pancreatic, oral, brain, lung and liver. It has be...
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Sensitivity, specificity and positive predictive value of ALEX2 multiplex examination in patients suffering from atopic dermatitis and reaction to tomatoes Food Agric. Immunol. (IF 3.0) Pub Date : 2023-10-03 Jarmila Čelakovská, Eva Čermákova, Radka Vaňková, Petra Boudková, Ctirad Andrýs, Jan Krejsek
The aim of the study is to evaluate the clinical reactions to tomatoes in atopic dermatitis (AD) patients, and to analyse the results of specific IgE to allergens of tomatoes and to molecular compo...
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Development of multiplex immunochromatographic assay for the simultaneous detection of three polyether ionophore antibiotics in chicken muscle Food Agric. Immunol. (IF 3.0) Pub Date : 2023-10-03 Zhixuan Sun, Yani Gu, Jingjie Huang, Jiancheng Li
A rapid, reliable, sensitive, and multiplex colloidal gold immunochromatographic assay (CGIA) was developed for the simultaneous detection of three polyether ionophore antibiotics (PEs) in chicken ...
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A combination of Polypodium leucotomos extract with vitamin A, vitamin C and selenium as an immune adjuvant against recurrent infections Food Agric. Immunol. (IF 3.0) Pub Date : 2023-09-14 Alejandra Visedo Colino, Flavia Tamara Hernández Rocamora, José Pardo Zapata, Julio Gosálbez, María del Mar Ortega-Villaizán Romo, Regla Maria Medina-Gali, David González Fernández, Alejandro Pérez-Fernández
ABSTRACT Plant chemodiversity is a helpful tool for disease prevention and a basis for adjuvant treatments to conventional therapies. In this regard, the extract of Polypodium leucotomos rhizomes, PLE, has shown benefits fighting inflammation and recurrent infections but its molecular mechanism is poorly undersood. This work shows that Plesinox 3A, containing PLE, Vitamins A, C, and selenium, helps
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Immunomodulation of RAW264.7 cells by CP80-1, a polysaccharide of Cordyceps cicadae, via Dectin-1/Syk/NF-κB signaling pathway Food Agric. Immunol. (IF 3.0) Pub Date : 2023-09-05 Jingqiong Wan, Yiling Zhu, Xue Jiang, Feixuan Wang, Zhaoyong Zhou, Jibiao Wang, Chang Liu, Yuan Wei, Zhen Ouyang
ABSTRACT Cordyceps cicadae is a rare edible and medicinal entomogenous fungus. Here, the structural characteristics and immunomodulatory activity of C. cicadae polysaccharide CP80-1 were preliminarily elucidated. It showed that CP80-1 of 250.431 kDa was mainly composed of glucose, xylose and rhamnose. Physiologically, CP80-1 can regulate the immune of RAW264.7 cells by promoting the proliferation,
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A simple and rapid DNA extraction method from meat by microneedle patch for detection of adulterated components Food Agric. Immunol. (IF 3.0) Pub Date : 2023-09-06 Weilun Hu, Mengxin Xu, Qingya Zeng, Yingying Li, Yuxin Zhang, Qingqing Wang, Tao Ma
ABSTRACT The simple and rapid identification of meat via DNA-based methods is still subject to the conditions of complex and time-consuming preprocessing. It usually takes 3–4 h to obtain DNA sample using conventionally available DNA extraction kits. The existing approaches are cumbersome, require large equipment, and are not suitable for field operation. This study developed a swelling microneedle
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Influence of Porphyra-derived polysaccharides and oligosaccharides on attenuating food allergy and modulating enteric microflora in mice Food Agric. Immunol. (IF 3.0) Pub Date : 2023-09-06 Yu-Jyun Wei, Rui-En Fang, Jia-Shan Liu, Yang-Ching Chen, Hong-Ting Victor Lin, Chorng-Liang Pan, Chung-Hsiung Huang
ABSTRACT Recently, there have been reports on the immunomodulatory properties of polysaccharides (PP), oligosaccharides (PO), and mixtures of PO/PP derived from Porphyra. To explore their potential in alleviating allergic responses and enteric dysbiosis, this study delved deeper into their effects using a murine model of food allergy. Daily administration of Porphyra samples mitigated allergic diarrhea
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Different iron sources affected haemoglobin and myoglobin synthesis, and gene expression related to iron metabolism in skeletal muscle in piglets Food Agric. Immunol. (IF 3.0) Pub Date : 2023-09-05 Ping Kang, Jiajun Fan, Qilong Xu, Dianchao Gu, Bingzhao Shi, Dan Wang, Huiling Zhu, Jiangchao Zhao, Yulan Liu
ABSTRACT This study was carried out to investigate the effect of different iron sources on haemoglobin and myoglobin (Mb) synthesis, and the mRNA expression of the key genes related to iron metabolism in the skeletal muscle of piglets. Forty-eight piglets were assigned into four treatments including control group, ferrous sulphate (FeSO4) group, ferrous glycinate (Fe-Gly) group and amino acid-Fe(II)-chelator
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Molecular mechanisms and biomarkers underlying the protective roles of the nutraceutical laminarin against ischaemic strokes Food Agric. Immunol. (IF 3.0) Pub Date : 2023-08-27 Jiefeng Luo, Yuan Lan, Wenwen Pan, Keng Po Lai, Deyan Kong
ABSTRACT Stroke is the second leading cause of death and a major cause of disability worldwide. Ischemic stroke accounts for approximately >60% of all stroke, and >80% of strokes can be prevented. Middle cerebral artery occlusion (MCAO) is a common cause of stroke in humans. MCAO is associated with blood vessel-related problems, such as reduced vascular plasticity and hypertension. These problems can
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Annotation of genes involved in gamma-aminobutyric multiplication during coix germination by metabolome and transcriptome analysis Food Agric. Immunol. (IF 3.0) Pub Date : 2023-08-11 Xiao Zhang, Yuqin Ding, Ying Hao, Guoqing Dong, Dengxiang Du, Dongao Huo
ABSTRACT Job’s tears (coix) is a widely used grain with rich and balanced nutritional value. In this study, a total of 71 metabolites, including amino acid metabolism, sugar metabolism and fatty acid metabolism, were significantly increased in the germinating coix through liquid chromatography tandem mass spectrometry (HPLC-MS/MS). Significant increase in gamma-aminobutyric (GABA) content during seed
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Paecilomyces cicadae: a systematic overview of the biological activities and potential mechanisms of its active metabolites Food Agric. Immunol. (IF 3.0) Pub Date : 2023-08-11 Di Feiqian, Zhang Jiachan, Cheng Wenjing, Li Luyao, Li Meng, Wang Changtao
ABSTRACT The microbe Paecilomyces cicadae (Miquel) Samson (P. cicadae) is an asexual strain of Cordyceps cicadae (C. cicadae) used in traditional Chinese medicine. Due to the abundance of secondary metabolites found in cultured metabolites, including polysaccharides, hyaluronic acid, ergosterol peroxide, and active nucleosides, P. cicadae and/or C. cicadae exhibit several therapeutic activities, including
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Study on the mechanism of Lu’an GuaPian tea in treating heart failure based on network pharmacology and molecular docking Food Agric. Immunol. (IF 3.0) Pub Date : 2023-08-03 Fang Hua, Ling-li Shi, Peng Zhou
ABSTRACT Objective The study was to investigate the possible mechanism of Lu'an GuaPian tea in treating heart failure (HF) via network pharmacology and molecular docking. Method The target of Lu'an GuaPian tea were screened. The GeneCards, NCBI, and DisGeNET databases were searched for HF targets. The GO and KEGG pathway analysis were used to obtain the targets and pathways. Molecular docking was used
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Sodium butyrate alleviates potential Alzheimer’s disease in vitro by suppressing Aβ and tau activation and ameliorates Aβ-induced toxicity Food Agric. Immunol. (IF 3.0) Pub Date : 2023-07-30 Al Borhan Bayazid, Yeong Hwan Jeong, Soo Ah Jeong, Beong Ou Lim
ABSTRACT The number of Alzheimer’s disease (AD) affected patients is increasing without any effective cure and the etiology remains to be understood. Inflammations, oxidative stress, Aβ, and tauopathy are associated factors of AD. Sodium butyrate (NaB) is an HDAC inhibitor profoundly found to be neuroprotective. We have investigated the neuroprotective effects of NaB in SH-SY5Y cells stimulated with
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Phillyrin attenuates airway inflammation and Th2 cell activities in a mouse asthma model Food Agric. Immunol. (IF 3.0) Pub Date : 2023-07-16 Wen-Chung Huang, Shu-Ju Wu, Li-Wen Fang, Tzu-Yung Lin, Chian-Jiun Liou
ABSTRACT Phillyrin is isolated from the fruit of Forsythia suspensa, and exhibits multiple pharmacological effects, including anti-tumor, anti-inflammation, and anti-oxidation activities. Here, we investigated whether phillyrin could alleviate airway hyperresponsiveness (AHR) and eosinophil infiltration in the lungs of asthmatic mice, and mitigate inflammatory responses in tracheal epithelial BEAS-2B
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Exosomes derived from berberine-treated bone marrow mesenchymal stem cells ameliorate inflammatory arthritis in rats with collagen-induced rheumatoid arthritis Food Agric. Immunol. (IF 3.0) Pub Date : 2023-07-06 Fei Sun, Yuxia Ma, Faxin Li, Congcong Li, Zhaowen Yang
To evaluate the effect of exosomes secreted by berberine-treated bone marrow-derived mesenchymal stem cells (BMSCs) on synovial inflammation in collagen-induced arthritis (CIA) model. Exosomes were...
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Immunostimulatory activity of Paeonia lactiflora through TLR4-dependent activation of p38, JNK, and ERK1/2 in mouse macrophages, RAW264.7 cells Food Agric. Immunol. (IF 3.0) Pub Date : 2023-07-06 Min Yeong Choi, So Jung Park, Jin Boo Jeong
ABSTRACT Paeonia lactiflora (P. lactiflora) has been recently reported to increase the production of proinflammatory mediators and activates phagocytosis in macrophages. Thus, in this study, we tried to verify the macrophage activation of Paeoniae Radix Rubra (PRR, also known as red peony root) and elucidate its mechanism of action. PRR upregulated the production of proinflammatory mediators and activated
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Oral administration of vermicompost tea ameliorates eczema skin inflammation via regulation of Th2 immune response Food Agric. Immunol. (IF 3.0) Pub Date : 2023-07-06 Huijiao Wen, Ci Lu, Runmeng Hu, Wenyang Shi, Libang Zhou, Puzhao Wen, Shan Jiang, Y. Martin Lo
Vermicompost tea (VCT) is the effluent or leachate with a honey-brown colour collected during vermicomposting, an ecologically significant process essential to today’s organic and regenerative agri...
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IFN-γ mediated neuroinflammation and behaviour abnormality after maternal exposure to low dose mixture of food additives and pesticides Food Agric. Immunol. (IF 3.0) Pub Date : 2023-07-06 Linyang Song, Xiaoyi He, Mengxia Wang, Lixia Li, Jing Liu, Guoying Li, Junhua Yang
People often simultaneously expose to acceptable/tolerable daily intake of food additives and pesticides in daily life. Exposure in adult rodents to acceptable/tolerable daily intake of food additi...
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Serotype and antimicrobial resistance of Salmonella from poultry meats in 2021 in Shanghai, China Food Agric. Immunol. (IF 3.0) Pub Date : 2023-06-18 Quan Xiao, Ying Yu, Biyao Xu, Zhixin Fang, Wenjie Chen, Jun Feng, Yanqi Zhu, Yue Liu, Qifang Gu, Jiayuan Luo, Xia Song, Zengfeng Zhang, Min Chen, Hongzhi Zhang
ABSTRACT Salmonella is a major cause of food poisoning, and its infection and antimicrobial resistance vary regionally due to different sanitary standards and the use of antimicrobials. The aim of this study is to evaluate the microbiological contamination and antimicrobial resistance of Salmonella in Shanghai, providing references for supervision over food safety and clinical treatment. This study
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Development of a novel polyclonal antibody against bovine αS1-casein IgE epitopes for prediction of potential allergenicity of milk in foods Food Agric. Immunol. (IF 3.0) Pub Date : 2023-06-18 Shengfa He, Caiyun Long, Liming Li, Yan Yan, Jinyu Li, Meng Xiong, Jiangqiang Zhao, Ziling Feng, Yang Li, Yaping Dong, Xin Li, Hongbing Chen
ABSTRACT Bovine αS1-casein (αS1-CN) is the main allergen in cow's milk, and immunoglobulin E (IgE) epitopes are the material basis to trigger allergic reactions. Thus, IgE epitopes could be as key targets for precise αS1-CN detection and allergenicity assessment. Here, we designed a tandem containing nine IgE linear epitopes of αS1-CN (tαS1-CN), expressed the recombinant tαS1-CN in Escherichia coli
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Effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages containing chitosan, by the ELISA method Food Agric. Immunol. (IF 3.0) Pub Date : 2023-06-18 L. Havlová, M. Pospiech, Z. Javůrková, M. Bartlová, K. Těšíková, D. Dordevic, S. Dordevic, J. Zemancová, B. Tremlová
ABSTRACT The aim of this study was evaluated the effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages based on chitosan using the ELISA. The analysed protein was the tropomyosin. The results confirmed the presence of the tropomyosin (3.77 ± 0.79–5.75 ± 0.01 µg/g) in control samples. This study demonstrated that the bioactive substances in the form of
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Transcriptomics reveals the potential mechanism of ellagic acid extract from raspberry on wound healing Food Agric. Immunol. (IF 3.0) Pub Date : 2023-06-09 Yongling Wu, Chang Liu, Wenjing Lu, Siting Li, Zhou Chen, Junxia Xia, Yiling Tian, Aijin Ma, Yingmin Jia
ABSTRACT The aim of this study was to reveal the mechanism of its wound healing function at the molecular level using transcriptome sequencing technology. The results showed that EAE mainly upregulated Cyclin A gene through AMPK signalling pathway, activated cell cycle pathway, promoted DNA synthesis, accelerated mitosis, and thus promoted the proliferation of Human immortalized keratinocytes (HaCaT)
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Protective mechanisms of intra- and extracellular polysaccharides from Schizophyllum commune on H2O2-induced oxidative damage of human skin fibroblasts Food Agric. Immunol. (IF 3.0) Pub Date : 2023-05-29 Wenjing Cheng, Yundong Yang, Jiachan Zhang, Fei qian Di, Luyao Li, Changtao Wang, Meng Li, Dan Zhao, Xiuqin Shi, Tong Huo, Quan An
ABSTRACT Schizophyllum commune is a fungus with applications both in medicine and foods, which produces IPS and EPS. However, there is no comparative study on the activity comparison of IPS and EPS and its mechanism of antioxidant effect. In this study, the antioxidant activities of the two polysaccharides were measured in biochemical, cellular and molecular levels, and H2O2 induced oxidative damage
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Deep-sea-derived viridicatol relieves allergic response by suppressing MAPK and JAK-STAT signalling pathways of RBL-2H3 cells Food Agric. Immunol. (IF 3.0) Pub Date : 2023-05-29 Yan Liu, Zhendan Shu, Yan Li, Huiying Chen, Hong Liu, Xianwen Yang, Guangming Liu, Qingmei Liu
ABSTRACT Our previous studies reported that viridicatol isolated from the deep-sea-derived fungus Penicillium griseofulvum could regulate the stabilisation of mast cells to relieve food allergy. To understand the molecular role of viridicatol in stabilising mast cells, transcriptomes of viridicatol-treated RBL-2H3 cells were analysed by RNA-sequencing. There were 128 differentially expressed genes
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Litopenaeus vannamei fermentation using selected Lactobacillus spp. to reduce its allergenicity Food Agric. Immunol. (IF 3.0) Pub Date : 2023-05-29 Hongyan Li, Zhihe Hu, Yali Yan
ABSTRACT Shrimp is a common cause of food allergies in allergic individuals. The management of patients suffering from shrimp allergy relies on avoidance of the specific food, which compromises nutritional requirements. In this study, fermentation was performed using Lactobacillus to reduce the allergenicity of Litopenaeus vannamei. The optimal fermentation conditions using Lactobacillus helveticus
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Simultaneous detection of OTA and AFB1 in cereals based on bispecific monoclonal antibody using quantum dot nanobead lateral flow immunoassay Food Agric. Immunol. (IF 3.0) Pub Date : 2023-05-09 Mengyun Wu, Jun Xia, Tingting Liu, Guangjian Xue, Xuechen Fang, Weihua Lai, Juan Peng
ABSTRACT Simultaneous contamination of ochratoxin A (OTA) and aflatoxin B1 (AFB1) in cereals are an ongoing global concern. For this reason, a sensitive method for the simultaneous detection of OTA and AFB1 in soybean, corn, and rice is required. Herein, we prepared a bispecific monoclonal antibody (BsMAb) that specifically recognized OTA and AFB1, and subsequently developed a quantum dot nanobead
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Crayfish shells-derived carbon dots as a fluorescence sensor for the selective detection of 4-nitrophenol Food Agric. Immunol. (IF 3.0) Pub Date : 2023-04-16 Jiannan Chen, Xiuhua Xia, Peizhen Li, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao, He Qian, Yuliang Cheng
ABSTRACT As a type of environmentally deleterious compound, 4-nitrophenol (4-NP) has become a global concern due to its extreme toxicity to aquatic organisms and humans. Herein, we used naturally available crayfish shells as precursors to prepare a new type of carbon dots (CDs) by the hydrothermal method. The as-synthesized CDs exhibited strong blue fluorescence emission which can be sensitively quenched
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RNA-seq based transcriptome analysis of murine macrophages RAW264.7 treated with multi-herbal extracts reveals immunomodulatory potential and mechanism Food Agric. Immunol. (IF 3.0) Pub Date : 2023-03-30 Meng-Yuan Jin, Xin Chen, Qin Wu, Zhi-Jian Guo, Rui Zhang, Yi-Fan Jiang, Xiang Li, Li-da Zhang, Yu-Liang Wang, Xuan-Wei Zhou
ABSTRACT Shenling Baizhu Powder is a traditional Chinese medicine formula that has been used for thousands of years to invigorate spleen, nourish stomach and regulate immune function. The multi-herbal extracts, an improved formular from Shenling Baizhu Powder, were used in our study to investigate its immune-enhancing effects and underling mechanisms. Based on UPLC-Q-TOF-MS and SPME-GC-MS analysis
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Rapid diagnosis of Tobacco mosaic virus in tobacco using time-resolved fluorescence immunoassay Food Agric. Immunol. (IF 3.0) Pub Date : 2023-03-18 Yuan Ji, Yushuang Guo, Huimin Deng, Jianfeng Zhang, Yuemao Wang, En Dai, Ziyan Fan, Gangling Tang, Mengao Jia, Bo Ding
ABSTRACT Tobacco mosaic virus (TMV) causes a significant yield loss in solanaceous crops. Accurate and rapid diagnosis of TMV is an essential pre-requisite for proactive and tailored disease management strategies, filling the gap between more rigorous laws regarding pesticide use and maintaining crop production. Herein, we developed a time-resolved fluorescence immunoassay (TRFIA) to quantitatively
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Cross-reactive aeroallergens – the main cause of food allergy Food Agric. Immunol. (IF 3.0) Pub Date : 2022-12-15 Adam Wawrzeńczyk, Emilia Rawicka, Katarzyna Napiórkowska-Baran, Ewa Alska, Zbigniew Bartuzi
ABSTRACT The aim of this study was to identify allergenic cross-reacting allergens in patients with inhalation and food allergy using molecular diagnostics ISAC test. The study group consisted of 50 adult patients. The control group contained 20 healthy people. In the study group 92% patients were found to have the asIgE component responsible for cross-allergy between plant pollens and foods. The presence
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Morphology-regulated core–shell Ag@Au NPs for rapid SERS detection of 1-amino-hydantoin (AHD) in crayfish Food Agric. Immunol. (IF 3.0) Pub Date : 2022-11-17 Peizhen Li, Xiuhua Xia, Jiannan Chen, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao, He Qian, Yuliang Cheng
ABSTRACT Gold-coated silver core–shell nanoparticles (Ag@Au NPs) have been widely used for SERS analysis due to plasmon resonance performances. However, it is a great challenge to fabricate Ag@Au core–shell structures with specified morphology. In this paper, the size and shape of Ag NPs (core) were precisely controlled by a seed-mediated approach, and then the gold shell was completely coated on under
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A semi-quantitative multi-range lateral flow immunoassay for amantadine residues in livestock and poultry products Food Agric. Immunol. (IF 3.0) Pub Date : 2022-10-30 Xiangxue Ning, Jing Qiu
ABSTRACT Amantadine is one of the most prescribed antiviral medications. Considering its abuse is life-threatening, monitoring amantadine residues is urgently needed. This study designed a dipstick assay based on lateral flow immunoassay (LFIA) platforms with an indicator range of 50–200 ng/mL. The dipstick consists of four coloured test lines that detect the concentration of amantadine semi-quantitatively
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The role of PR 10 proteins and molecular components of moulds and yeast in atopic dermatitis patients Food Agric. Immunol. (IF 3.0) Pub Date : 2022-10-20 J. Čelakovská, R. Vaňková, H. Skalská, J. Krejsek, C. Andrýs
ABSTRACT This study aims to analyse the results of specific IgE to molecular components of PR 10 proteins, mould and yeast in atopic dermatitis (AD) patients, to find significant sets of molecular components in pairs and triplets in the relation to the severity of atopic dermatitis and the occurrence of asthma bronchiale and allergic rhinitis. The examination of the sensitization to molecular components
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Ginsenoside compound K induces mitochondrial apoptosis in human hepatoma cells through Bclaf1-mediated modulation of ERK signaling Food Agric. Immunol. (IF 3.0) Pub Date : 2022-10-20 Jiaxin Chen, Manqing Sun, Xinmu Cui, Xuewu Zhang
ABSTRACT Compound K (CK) is the metabolite and final active ingredient of diol-type ginsenosides. In this study, we investigated the effect of CK on mitochondrial apoptosis in SMMC-7721 and BEL-7404 cells and the regulatory mechanism through in vitro and in vivo experiments. The results demonstrated that CK inhibited Hepatocellular carcinoma (HCC) cells proliferation and arrested the cells in G0/G1
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Effect of velvet antler on the immune activity of cyclophosphamide-induced immunosuppressed mice Food Agric. Immunol. (IF 3.0) Pub Date : 2022-10-10 Liu Song-xin, Li Zhi-man, Shao Zi-jun, Xia Yun-shi, Zhao Li-juan, Ren Duo-duo, Sun Yin-shi
ABSTRACT To study the antioxidant and immune protection activity of velvet antler (VA) in cyclophosphamide-induced immunocompromised mice, BALB/c mice were intragastrically administered 100, 300, or 500 mg/(kg·d) VA for 30 days, and were intraabdominally injected with cyclophosphamide to create a hypoimmune murine model. Cellular immunity, macrophage phagocytic activity, natural killer (NK) cell activity
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A SERS-based immunochromatographic assay for ultrasensitive and quantitative detection of florfenicol using long wavelength absorption of Au nanocubes Food Agric. Immunol. (IF 3.0) Pub Date : 2022-10-04 Ying Liu, Ting Zhou, Penghui Zhou, Hanwen Liu, Jianguo Li, Anping Deng
ABSTRACT An immunochromatographic assay (ICA) based on surface-enhanced Raman scattering (SERS) for ultrasensitive and quantitative detection of florfenicol (FF) in food samples was developed. Au nanocubers (AuNCs) with long wavelength absorption were synthesised, characterised and used as the substrate in SERS-ICA. Immunoprobe was prepared by linking Raman reporter and the antibody against FF on AuNCs
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Preparation of fermented oat milk and evaluation of its modulatory effect on antigen-specific immune responses in ovalbumin-sensitized mice Food Agric. Immunol. (IF 3.0) Pub Date : 2022-09-21 Fang-Ling Liu, Chien-Li Chen, Chung-Hsiung Huang
ABSTRACT A growing number of people choose plant-based milk products to replace dairy for health reasons or veganism. Since fermentation is a promising method to improve the nutritional value of plant-based milk, this study aimed to establish the process of oat milk fermentation and to evaluate the effect of fermented oat milk (FOM) on modulating antigen-specific immune response in ovalbumin (OVA)-sensitized
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Metabolomics and water migration analysis provides valuable insights into nutrient generation in Tartary buckwheat (Fagopyrum tataricum) seed germination Food Agric. Immunol. (IF 3.0) Pub Date : 2022-09-19 Bai Yongliang, Xin Meiguo, Lin Roumin, He Weijun, He Shuyan, Zeng Rong, Guo Yiping
ABSTRACT Seed germination of Tartary buckwheat is important for its biological generation of various nutrients. To investigate the nutrient differences during seed germination, the metabolic profiling and moisture status of Tartary buckwheat seed germination were quantitatively measured by ultra-high performance liquid chromatography mass spectrometry (UHPLC-MS) and NMR, respectively. The results showed
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Rapid screening of 15 highly toxic pesticide residues in Angelica sinensis decoctions by thermal desorption electrospray ionization mass spectrometry Food Agric. Immunol. (IF 3.0) Pub Date : 2022-09-20 Hongyan Zhang, Qiaoying Chang, Xingzhi Wang, Jian Li, Guoyu Qiu, Fuxiang Wu, Renyuan Zhu, Ming Su
ABSTRACT A decoction is the most common form of Chinese herbal medicine dosing. An Angelica sinensis decoction was qualitatively and semi-quantitatively analyzed for 15 highly toxic pesticide residues by thermal desorption electrospray ionization mass spectrometry (TD-ESI/MS) with a triple quadrupole mass spectrometer in multiple reaction monitoring mode without pretreatment. The instrument response
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A study on the anti-skin tumor and anti-UVB damage effects of Gastrodia elata Bl. Products transformed by Armillaria mellea Food Agric. Immunol. (IF 3.0) Pub Date : 2022-09-19 Tong Zheng, Yugang Gao, Zhilong Zhang, XinYue Li, Pu Zang, Yan Zhao, Zhongmei He
ABSTRACT Skin cancer is a malignant tumour that can spread in the skin and is a serious threat to human health. Excessive ultraviolet radiation is one of the most common factors that leads to skin cancer. The purpose of this study was to evaluate the anti-skin tumour and anti-UVB damage effects of Armillaria mellea (Vahl) P. Kumm transformed Gastrodia elata Bl products (ATGP). Gastrodia elata Blume
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Rapid enzyme-linked immunosorbent assay and colloidal gold immunoassay for assessing okadaic acid and its derivatives in shellfish Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-31 Ruirui Wang, Hongli Qi, Miao Liang, Guoxiang Liao, Fan Yang
ABSTRACT Okadaic acid (OA) and the analogs of dinophysistoxin (DTX) are important members of diarrhetic shellfish poisoning (DSP) toxins. In this study, five OA-specific mAbs (monoclonal antibodies) were developed from five stable cells of hybridoma. The anti-OA mAb-2D7 showed high sensitivity to OA, the IC50 of the antibody was 0.24 ng/mL, and its cross-reactivity was 91.6% with DTX-1 and 110.5% with
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Curcumin inhibits invasion and metastasis of human hepatoma cells through Bclaf1-mediated Wnt/β-catenin signalling Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-28 Zhongwei Zhao, Jielin Su, Jiaqi Zhao, Jiaxin Chen, Xinmu Cui, Manqing Sun, Xuewu Zhang
ABSTRACT Curcumin, a kind of natural compound extracted from the rhizome of Zingiberaceae such as turmeric, has many pharmacological effects such as anti-cancer effects. This study investigated the effect of curcumin on the invasion and metastasis of hepatocellular carcinoma (HCC) cell lines HepG2 and SK-Hep-1 through the Wnt/β-catenin signalling pathway and the regulatory mechanism of Bcl-2-associated
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Identification and characterization of MicroRNAs in pig liver after the LPS challenge using RNA-seq Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-22 Yang Yang, Qingqing Lv, Xingfa Huang, Jiajun Fan, Pei Li, Huling Zhu, Ping Kang, Yulan Liu
ABSTRACT This study was conducted to test the expression profiles of miRNAs in the liver in piglets after the LPS challenge using sequencing technology. Twelve barrows were assigned to two groups, including the saline group and the LPS group. Six small RNA (sRNA) libraries were constructed, and novel miRNAs were identified using mirevo and mirdeep2 software and validated by quantitative real-time PCR
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Immune-enhancing effects of Hibiscus syriacus roots in RAW264.7 macrcophages Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-16 Hyun Ji Eo, Yunmi Park, Hae Yun Kwon, Gwang Hun Park
ABSTRACT In this study, we evaluated whether extracts of the roots of Hibiscus syriacus (HSR) exert immune activation activities and elucidated its potential mechanism in macrophages. The HSR dose-dependently increased the production of immunomodulators such as nitric oxide (NO), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), interleukin-1β (IL-1β), and tumor necrosis factor (TNF-α)
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Solanum nigrum induces macrophage activation through TLR4-mediated activation of JNK and macrophage autophagy through TLR4-mediated activation of p38 and JNK Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-16 Ju Hyung Yu, Min Yeong Choi, So Jung Park, Na Gyeong Geum, Jae Won Lee, Gwang Hun Park, Hyun Ji Eo, Jin Boo Jeong
ABSTRACT In this study, we investigated the effect of Solanum nigrum aerial parts (SNAP) on macrophage activation and macrophage autophagy in RAW264.7 cells. SNAP increased the production of immunostimulatory factors and phagocytosis in RAW264.7 cells. TLR4 inhibition blocked SNAP-mediated production of immunostimulatory factors. In addition, the JNK inhibition reduced the SNAP-mediated production
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Design and synthesis of geosmin derivatives using organic synthesis strategies and application in antibody production Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-11 Penghui Zhou, Ying Liu, Ting Zhou, Hanwen Liu, Jianguo Li, Anping Deng
ABSTRACT To develop a sensitive and specific ELISA for geosmin (GSM), the research of this study is focused on the design and synthesis of several GSM derivatives, which maintain the whole GSM structure as much as possible and contain a spacer arm with an active group at the end. To form the GSM backbone, tandem organic reaction strategies were used to replace the traditional Robinson cyclization reaction
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Sensitisation to molecular components of mites in atopic dermatitis patients Food Agric. Immunol. (IF 3.0) Pub Date : 2022-08-04 J. Čelakovská, E. Čermákova, R. Vaňková, P. Boudkova, C. Andrýs, J. Krejsek
ABSTRACT Background and aim: To analyse the sensitisation profile to molecular components of mites allergens with the use of ALEX2 Allergy Explorer test in Atopic dermatitis (AD) patients. Method: The complete dermatological and allergological examination including the examination of the sensitisation to molecular components with ALEX2 Allergy Explorer testing was performed. For the statistical analysis