-
OsteoMac: a new player on the bone biology scene Ann. Anat. (IF 2.2) Pub Date : 2024-03-14 Iglesias-Velazquez Oscar, Tresguerres Francisco GF, Tresguerres Isabel F, Leco-Berrocal Isabel, Lopez-Pintor Rosa, Baca Laura, Torres Jesus
The knowledge of bone biology has undergone major advances in recent decades. In bone, resorbing osteoclasts have classically been described as tissue-resident macrophages, however, it is currently known that a new subtype of macrophages, called OsteoMacs, are specialised bone-resident macrophages, which, depending on certain conditions, may play an important role not only in bone homeostasis, but
-
Effect of type 2 diabetes mellitus on the microstructural, compositional and mechanical properties of cartilages Ann. Anat. (IF 2.2) Pub Date : 2024-03-14 Chao Wan, Zhongjie Li, Yizun Zhou
Osteoarthritis (OA) is a chronic and complicated degenerative disorder of joints, including several phenotypes. Type 2 diabetes mellitus (T2DM) is one of the major causes of OA. However, few studies on the mechanical behavior of diabetic cartilages have been conducted. This study evaluated the microstructural, compositional, and mechanical properties of healthy and diabetic rat cartilages using scanning
-
Growing stylohyoideus muscle insertion to the hyoid bone with special reference to its topographical relation to the intermediate tendon of digastricus muscle: a histological study using human fetuses Ann. Anat. (IF 2.2) Pub Date : 2024-03-08 Kei Kitamura, Ryu Suzuki, Satoshi Ishizuka, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Hitoshi Yamamoto, Shin-ichi Abe
In adults, the intermediate tendon of digastricus muscle usually runs along the medial or lateral side of the stylohyoideus muscle insertion. To provide a better understanding of the variations, we examined the topographical anatomy of the muscle and tendon in fetuses. We examined histological sections from six early-term, 26 mid-term and six near-term fetuses (approximately 8-9, 12-18 weeks and 25-33
-
Exploring the sex-associated differences in molars fused roots Ann. Anat. (IF 2.2) Pub Date : 2024-03-08 Maria Eduarda Nunis Locks, Erika Calvano Küchler, Leonardo Santos Antunes, Alice Corrêa Silva-Sousa, Natanael Henrique Ribeiro Mattos, Camila Paiva Perin, Paulo Henrique Condeixa de França, Peter Proff, Christian Kirschneck, Flares Baratto-Filho
Human sexual dimorphism is associated with many biological characteristics, including dental variables. To investigate if molars fused roots present sex-associated differences. Panoramic radiographs were used to investigate the frequency and distribution of permanent molars fused roots. Only patients with all first and second permanent molars were included. Third molars were not investigated. Any molar
-
Historical trends and current experiences of anatomical body donation in two Zimbabwean medical schools Ann. Anat. (IF 2.2) Pub Date : 2024-03-07 Phillipa Marima, Josephine Tendai Chidaushe, Svetlana King, Fidelis Chibhabha
Body donation is integral to anatomy education, but procurement can be ethically fraught. While voluntary donation is preferred, the use of unclaimed bodies, although considered unethical, is a primary means for body procurement in some countries. This mixed methods study examined historical trends and anatomy technical staff perspectives on body donation in two Zimbabwean medical schools. In Phase
-
First standardized assessment of perforators and perforasomes of the occipital artery – An anatomical study Ann. Anat. (IF 2.2) Pub Date : 2024-03-07 Sam Augustine Kandathil, Lukas Sebastian Dengler, Lena Hirtler
Flaps have become an integral part of plastic and reconstructive surgery. The robust blood supply of such flaps is a prerequisite to reduce flap failure. Despite the reported versatility of the occipital flap, comprehensive anatomical studies on its perforators and perforasomes are lacking. Hence, we examined the perforators originating from the occipital artery and their associated perforasomes, aiming
-
Postmortem sympathomimetic iris excitability Ann. Anat. (IF 2.2) Pub Date : 2024-03-07 Colya N. Englisch, Reem Alrefai, Cristina Martin Lesan, Berthold Seitz, Thomas Tschernig
A reliable estimation of time since death can be important for the law enforcement authorities. The compound method encompassing supravital reactions such as the chemical excitability of the iris can be used to further narrow intervals estimated by temperature-based methods. Postmortem iris excitability was mostly assessed by parasympatholytic or parasympathomimetic substances. Little is known regarding
-
Netrin-1 as A neural guidance protein in development and reinnervation of the larynx Ann. Anat. (IF 2.2) Pub Date : 2024-03-06 Ignacio Hernandez-Morato, Shira Koss, Emily Honzel, Michael J. Pitman
Neural guidance proteins participate in motor neuron migration, axonal projection, and muscle fiber innervation during development. One of the guidance proteins that participates in axonal pathfinding is Netrin-1. Despite the well-known role of Netrin-1 in embryogenesis of central nervous tissue, it is still unclear how the expression of this guidance protein contributes to primary innervation of the
-
Anatomical considerations of the sural nerve in the distal leg: Side branch patterns and significance in nerve harvesting procedures Ann. Anat. (IF 2.2) Pub Date : 2024-03-06 Anhelina Khadanovich, Daniela Trachtova, Radek Kaiser, Michal Benes, Adam Whitley, David Kachlik
The sural nerve is a somatosensory nerve that provides sensation to the posterolateral aspect of the lower leg and the lateral part of the ankle and foot. Due to its location and anatomical properties, it is often used as an autologous nerve graft. However, the nerve harvest can be complicated by the presence of side branches. The objective of this study was to investigate the anatomy of the sural
-
The structure and function of the human choroid Ann. Anat. (IF 2.2) Pub Date : 2024-03-02 Weina Zhang, Alexandra Kaser-Eichberger, Wanlin Fan, Christian Platzl, Falk Schrödl, Ludwig M. Heindl
In this manuscript, the structure of the human choroid is reviewed with emphasis of the macro- and microscopic anatomy including Bruch’s membrane, choriocapillaris, Sattler’s and Haller’s layer, and the suprachoroid. We here discuss the development of the choroid, as well as the question of choroidal lymphatics, and further the neuronal control of this tissue, as well as the pathologic angiogenesis
-
Calcification patterns and morphology of Sella turcica are related to anteroposterior skeletal malocclusions: A cross-sectional study Ann. Anat. (IF 2.2) Pub Date : 2024-02-29 João Armando Brancher, Larissa Alves Maciel da Silva, Caio Luiz Bitencourt Reis, Mírian Aiko Nakane Matsumoto, Leo de Carvalho, Leonardo Santos Antunes, L.ívia Azeredo Alves Antunes, Maria Bernadete Sasso Stuani, Maria Fernanda Torres, Eva Paddenberg-Schubert, Christian Kirschneck, Erika Calvano Küchler
The sphenoid bone is an irregular, unpaired, symmetrical bone located in the middle of the anterior skull and is involved in craniofacial growth and development. Since the morphology of Sella turcica (ST) is associated with different craniofacial patterns, this study aimed to investigate if there is a correlation between ST morphology on the one hand and sagittal craniofacial patterns on the other
-
Evaluation of the (clinical) relevance of gross anatomical teaching for dental students and practicing oral surgeons in Berlin Ann. Anat. (IF 2.2) Pub Date : 2024-02-28 Gerald Buhlheller, Anna Steinborn, Irene Brunk
Knowledge of human anatomy is an important scientific basis for every dentist, and the adequacy of its provision by anatomy faculties is therefore constantly being adapted. Students' motivation to comprehend knowledge is a fundamental prerequisite and has been shown to increase when the relevance of the subject is clear. This study examines dental students' perceptions of the relevance of the anatomy
-
Challenges in Sourcing Bodies for Anatomy Education and Research in Ethiopia: Pre and Post COVID-19 Scenarios Ann. Anat. (IF 2.2) Pub Date : 2024-02-27 Amenu Tolera Wirtu, Arthur Tsalani Manjatika
The relevance of anatomical dissection in instructing anatomy to medical, dental, and other health science students is indisputable. Ethiopian anatomists encountered challenges in obtaining human bodies for anatomy education and research, both prior to and following the COVID-19 outbreak. The challenges intensified during the pandemic, significantly affecting anatomy education in Ethiopia. This study
-
Cochlear aqueduct revisited: A histological study using human fetuses Ann. Anat. (IF 2.2) Pub Date : 2024-02-26 Kwang Ho Cho, Ji Hyun Kim, Yohei Honkura, Masahito Yamamoto, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Yukio Katori
The cochlear aqueduct (CA) connects between the perilymphatic space of the cochlea and the subarachnoid space in the posterior cranial fossa. The study aimed to examine 1) whether cavitation of the CA occurs on the subarachnoid side or the cochlear side and 2) the growth and/or degeneration of the CA and its concomitant vein. We examined paraffin-embedded histological sections from human fetuses: 15
-
New Anatomical Concepts regarding Pubic-Related Groin Pain: A Dissection Study Ann. Anat. (IF 2.2) Pub Date : 2024-02-24 Thomas Mathieu, Francis Van Glabbeek, Lenie Denteneer, Levi Van Winckel, Emile Schacht, Benjamin De Vlam, Luc Van Nassauw
Pubis-related groin pain remains a difficult topic in orthopedic and sports medicine. A better understanding of the anatomy of the adductors and the pubic ligaments is necessary. The aim of this study is to map all the musculotendinous attachments to the pubic ligaments and to investigate in detail all the possible inter-adductor fusions. The pubic symphyses were dissected in eight male and fourteen
-
Preliminary evaluation of fish cartilage as a promising biomaterial in cartilage tissue engineering Ann. Anat. (IF 2.2) Pub Date : 2024-02-24 Abbas Zamani, Maryam Khajavi, Masoumeh Haghbin Nazarpak, Atefeh Solouk, Maryam Atef
Fish cartilage is known as a valuable source of natural biomaterials due to its unique composition and properties. It contains a variety of bioactive components that contribute to its potential applications in different domains such as tissue engineering. The present work aimed to consider the properties of backbone cartilage from fish with a cartilaginous skeleton, including elasmobranch (reticulate
-
Investigation of the Use of Gelatine-Glycerine and Gelatine-Polyvinyl Alcohol Mixtures as Tissue Consistency Preservatives in Cadavers Fixed with Modified SEFS Solution Ann. Anat. (IF 2.2) Pub Date : 2024-02-24 Zeynep İpek ORUÇ, Erkut TURAN
This study aimed to improve the effectiveness of SEFS, a fixing solution composed of soap and ethanol. This was achieved by modifying the formulation of SEFS. Additionally, this study aimed to preserve the consistency of organs by perfusing cadavers with mixtures of gelatine-glycerin (gelatine-Gls) and gelatine-polyvinyl alcohol (gelatine-PVA) through vascular access. The modified SEFS embalmed cadavers
-
Mathematical definition and rules of the splitting/merging patterns in bundles of human peripheral nerve segment Ann. Anat. (IF 2.2) Pub Date : 2024-02-21 Yingchun Zhong, Peng Luo, Xiaoyue Wen, Biao Wang, Chengfan Zhong, Shuang Zhu
Accurately measuring the spatial extension distance of nerve bundles in completing a split/merge is impossible because no clear mathematical definition exists for the starting and ending positions in nerve-bundle splitting/merging. We manually count the number of nerve-bundle splits/merges in long nerve segments, which is labor-intensive, inefficient, and prone to counting errors. Currently, the mathematics
-
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice Ann. Anat. (IF 2.2) Pub Date : 2024-02-16 Yanan Zhang, Fangrui Hu, Hui Li, Qinli Duan, Yalei Pi, Yuqian Li, Huifeng Zhang
3 M syndrome is first reported in 1975,which characterized by severe pre- and postnatal growth retardation, skeletal malformation and facial dysmorphism. These three genes (CUL7, OBSL1 and CCDC8) have been identified to be respond for 3 M syndrome, of which CUL7 is accounting for approximately 70%. To date, the molecular mechanism underlying the pathogenesis of 3 M syndrome remains poorly understood
-
Three-dimensional measurements of symmetry for the mandibular ramus Ann. Anat. (IF 2.2) Pub Date : 2024-02-16 Adrian Franke, Anastasia Franziska Sequenc, Philipp Sembdner, Alexander Seidler, Jan Bernard Matschke, Henry Leonhardt
The study examines a sample of patients presenting for viscerocranial computer tomography that does not display any apparent signs of asymmetry, assesses the three-dimensional congruency of the mandibular ramus, and focuses on differences in age and gender. This cross-sectional cohort study screened viscerocranial CT data of patients without deformation or developmental anomalies. Segmentations were
-
An examination of the status, contexts of anatomical body donation, and perspectives in China Ann. Anat. (IF 2.2) Pub Date : 2024-02-16 Airong Ma, Ying Ding, Jianfei Lu, Yan Wo, Wenlong Ding
Body donation is a valuable resource in medical education, research, clinical diagnosis, and treatment. Consequently, donors are honored as “Silent Mentors” in Chinese medical schools. This article briefly reviews the history, current status, and strategies to promote body donation in China (excluding data from Hong Kong, Macao, and Taiwan regions) and discusses the problems encountered in body donation
-
Evolution and development of extraocular motor neurons, nerves and muscles in vertebrates Ann. Anat. (IF 2.2) Pub Date : 2024-02-10 Bernd Fritzsch
The purpose of this review is to analyze the origin of ocular motor neurons, define the pattern of innervation of nerve fibers that project to the extraocular eye muscles (EOMs), describe congenital disorders that alter the development of ocular motor neurons, and provide an overview of vestibular pathway inputs to ocular motor nuclei. Six eye muscles are innervated by axons of three ocular motor neurons
-
Morphological differences between the dorsal and palmar septa of the first extensor compartment in relation to the brachioradialis and pronator quadratus Ann. Anat. (IF 2.2) Pub Date : 2024-02-09 Yuka Nishimura, Masahiro Tsutsumi, Rintaro Yamamoto, Tohma Sakuraya, Kenji Emura, Takamitsu Arakawa
The first extensor compartment of the wrist is known as a frequent site of stenosing tenosynovitis, referred to as de Quervain’s disease. De Quervain’s disease occurs more frequently in the dorsal part of the first extensor compartment than in the palmar part; however, the anatomical reason why the dorsal part is worse remains poorly elucidated. This study clarified the morphological differences between
-
Spatiotemporal expression profiles of c-Mpl mRNA in the tooth germ: Comparative expression dynamics of vascularization-related genes Ann. Anat. (IF 2.2) Pub Date : 2024-02-08 Masataka Sunohara, Shigeru Morikawa, Kazuto Shimada, Kingo Suzuki
Vascularization is an essential event for both embryonic organ development and tissue repair in adults. During mouse tooth development, endothelial cells migrate into dental papilla during the cap stage, and form blood vessels through angiogenesis. Megakaryocytes and/or platelets, as other hematopoietic cells, express angiogenic molecules and can promote angiogenesis in adult tissues. However, it remains
-
The retromandibular loop of the external carotid artery Ann. Anat. (IF 2.2) Pub Date : 2024-02-07 Cătălin Constantin Dumitru, Alexandra Diana Vrapciu, Adelina Maria Jianu, Sorin Hostiuc, Mugurel Constantin Rusu
The external carotid artery (ECA) is a major artery of the head and neck. Although numerous studies describe the variability of ECA branches, the course variation of the ECA was seemingly overlooked. It was aimed to study the morphological possibilities of the retromandibular segment of the ECA. A retrospective study was performed on 60 computed tomography angiograms of 26 male and 31 female adult
-
Morphofunctional and histological patterns of blood vessels in the superficial cervicofacial musculoaponeurotic system in midlateral face regions Ann. Anat. (IF 2.2) Pub Date : 2024-02-01 Ramona Paula Cucu, Marius Valeriu Hînganu, Victor-Vlad Costan, Ludmila Lozneanu, Otilia Boişteanu, Camelia Tamaş, Dragoş Negru, Delia Hînganu
The superficial cervicofacial musculoaponeurotic system (SMAS) is a complex network formed by mimic muscles and conjunctive tissue of the superficial fascia of the face.This study aimed to introduce new anatomofunctional data on the importance of the trans-SMAS distribution pattern of the skin microperfusion of the face and to underline the role of SMAS in maintaining the homeostasis of the vascular
-
-
Bilateral duplicated inferior vena cava associated with aberrant internal iliac and gonadal veins: A case-based narrative review Ann. Anat. (IF 2.2) Pub Date : 2024-01-29 Arthur Tsalani Manjatika, Pedzisai Mazengenya, Joshua Gabriel Davimes
The left side anterior retroperitoneal approach is preferred for the management of lumbosacral spine disorders as there is reduced risk for vascular injury. The presence of multiple and uncommon venous variations on either side of the spine, like the bilateral duplicated inferior vena cava (DIVC), may complicate surgery in this region. The current study describes two rare cases of bilateral duplicated
-
Evaluation of the celiac trunk and its branching pattern by magnetic resonance angiography Ann. Anat. (IF 2.2) Pub Date : 2024-01-29 Necmi Keskin, Belgin Bamac, Ozgur Cakir, Ercument Ciftci, Tuncay Colak, Cagatay Barut
The study aimed to examine the celiac trunk (CT) in detail by magnetic resonance angiography, to determine the locations, positions and variations of the CT, to provide detailed information for surgeons and interventional radiologists, and to reduce the time spent in the catheter angiography. MR angiography images of 185 patients with abdominal imaging in PACS (Picture Archiving Communication Systems)
-
Wilhelm Waldeyer as an object – Anatomists as body donors Ann. Anat. (IF 2.2) Pub Date : 2024-01-24 Andreas Winkelmann
Berlin anatomist Wilhelm von Waldeyer-Hartz (1836–1921) donated his skull, brain, and hands to his institute. Only the skull survives in the present-day collection. This study investigates the skull itself as much as the historical context of Waldeyer's donation. Physical-anthropological investigation of the remains and historical research. Waldeyer's main motivation was the donation of his brain to
-
Comparison of the study performance of dental students in different subfields of neuroanatomy at the Charité - Universitätsmedizin Berlin and evaluation of the neuroanatomy course in the fourth preclinical semester Ann. Anat. (IF 2.2) Pub Date : 2024-01-21 Lena Gökinan, Anna Steinborn, Irene Brunk
The dentist's main working area is the head and neck region, which is innervated by the cranial nerves. On a daily basis, dentists must administer local anaesthesia to ensure pain-free treatment and differentiate between dental pain and neuropathies to avoid mistreatment. Therefore, neuroanatomical training, especially on the cranial nerves, is of immense importance for clinical practice. In order
-
Effect of bone mass density and alveolar bone resorption on stress in implant restoration of free-end edentulous posterior mandible: Finite element analysis of double-factor sensitivity Ann. Anat. (IF 2.2) Pub Date : 2024-01-18 Zhangyan Ye, Hao Ye, Yue Wu, Zhengting Jiang, Huiyu Yao, Xiaomin Xu, Yitian Zhang, Weifeng Du, Wenshan Li, Yuwei Zheng, Pengcheng Ye, Xi Ding, Lijun Wu
Osseous condition of the mandible was regarded as a key factor influencing stability of implants in the early stage. Finite element analysis was used to assess the effect of bone mass density and alveolar bone resorption (double factors) on stress in a four-unit implant restoration of a free-end edentulous posterior mandible. A 3D finite element model was constructed for a single-sided free-end edentulous
-
Acquisition of cadavers for anatomy education and research in Malawi Ann. Anat. (IF 2.2) Pub Date : 2024-01-18 Arthur Tsalani Manjatika, Joshua Gabriel Davimes, Anthony Mwakikunga
The use of human cadaveric dissection forms an essential part of teaching anatomy to health sciences students in Malawi. Despite worldwide struggles in acquiring sufficient human cadavers for anatomy education, the current recommendations on the best anatomy practices require the use of cadavers exclusively from the body donation programs. The current study aims to describe the sources of cadaveric
-
The tendon of the fibularis brevis muscle – Systematic overview and new classification system Ann. Anat. (IF 2.2) Pub Date : 2024-01-09 Nicol Zielinska, R. Shane Tubbs, Bartosz Gonera, Georgi P. Georgiev, Friedrich Paulsen, Łukasz Olewnik
The fibularis brevis muscle belongs to the lateral compartment of the leg. It originates from the lower two-thirds of the lateral surface of the fibula bone and it also is attached to the anterior intermuscular septum. Its insertion is normally located on the tuberosity at the base of the fifth metatarsal bone, on its lateral side. However, distal attachment of this muscle is morphologically variable
-
Internal vascular anatomy of the human lacrimal gland: A protocol based on cadaver dissection and three-dimensional micro-computed tomography Ann. Anat. (IF 2.2) Pub Date : 2023-12-29 Swati Singh, Prakshi Chopra, Fabian Necker, Michael Scholz, Anna-Maria Liphardt, Louis Schuster, Friedrich Paulsen, Lars Bräuer
Purpose To evaluate the feasibility of studying the vascular supply of the orbital and palpebral lobes of the human lacrimal gland using micro-computed tomography (micro-CT) and microscopic dissection. Methods The lacrimal gland artery of a fresh parasagittalized cadaver head (male, aged 76 years) was infused with a lead oxide-latex mixture near the occipital pole of the gland. The entire lacrimal
-
Sensory innervation of the human shoulder joints in healthy and in chronic pain shoulder syndromes Ann. Anat. (IF 2.2) Pub Date : 2023-12-26 Abel Martínez-Gago, Yolanda García-Mesa, Patricia Cuendias, José Martín-Cruces, Juan F. Abellán, Olivia García-Suárez, José A. Vega
Background Afferent innervation of shoulder joints plays a fundamental role in nociception and mechanoception and its alteration result in shoulder´s disease that course with pain and functional disability. Methods Joints shoulder from healthy subjects (n = 20) and with chronic pain shoulder syndromes (n = 17) were analyzed using immunohistochemistry for S100 protein to identify nerve structures (nerve
-
Hotspots of facial artery perforators and perforasomes for easier flap guidance: An anatomical study Ann. Anat. (IF 2.2) Pub Date : 2023-12-22 Sam A. Kandathil, Vinzenz Berger, Giuseppe Roccuzzo, Lena Hirtler
Background The facial artery perforator flap is a valuable alternative for reconstruction of small to medium defects in the central midface and provide pleasing cosmetic results, allowing reconstruction in a one-stage procedure. Since Doppler ultrasound is not applicable to distinguish perforator from source artery, anatomical studies are needed to identify perforator areas along the course of the
-
Hepatic portal vein branching patterns according to different liver assessment methods and classifications of branching type Ann. Anat. (IF 2.2) Pub Date : 2023-12-23 J. Tutkuviene, A. Navakauskaite, R. Narutyte, A. Brazaitis, A. Barkus, A. Tamosiunas
Background It is known that there are varying frequencies of hepatic portal vein branching patterns found in the literature. Studies use different methods and classifications to evaluate the anatomy of the portal vein, which limits accurate comparison between studies and the determination of true frequency of branching patterns in different populations. The aim of the present study was to investigate
-
Regenerative effect of microcarrier form of acellular dermal matrix versus bone matrix bio-scaffolds loaded with adipose stem cells on rat bone defect Ann. Anat. (IF 2.2) Pub Date : 2023-12-19 Alshaymaa Gamal Aboulkhair, Asmaa A. AboZeid, Hanan Hassan Beherei, Samaa Samir Kamar
-
Clinical anatomy of the lateral antebrachial cutaneous nerve: Is there any safe zone for interventional approach? Ann. Anat. (IF 2.2) Pub Date : 2023-12-19 Anhelina Khadanovich, Michal Benes, Radek Kaiser, Tomas Herma, David Kachlik
Introduction The lateral antebrachial cutaneous nerve (LACN) is a somatosensory nerve coursing in the lateral portion of the forearm. The nerve is located in a close proximity to the cephalic vein (CV) all along its course with a danger of being injured during venipuncture. The LACN also overlaps and communicates with the superficial branch of the radial nerve (SBRN) in the distal forearm and hand
-
Pathways and morphologic pattern of blood supply of epicardial ganglionated nerve plexus Ann. Anat. (IF 2.2) Pub Date : 2023-12-19 Dmitrij Kvitka, Dainius H. Pauza
Detailed cardiac neuroanatomy is critical for understanding cardiac function and its pathology. However, there remains a significant gap in knowledge regarding the blood supply to the intrinsic cardiac ganglionated plexus (GP). This study addresses this by mapping the routes and morphological pattern of blood supply to the epicardial GP in a large-animal pig model (Sus scrofa domesticus). Twenty-five
-
Immunohistochemical detection of PIEZO1 and PIEZO2 in human digital Meissner´s corpuscles Ann. Anat. (IF 2.2) Pub Date : 2023-12-17 Yolanda García-Mesa, Patricia Cuendias, Marta Alonso-Guervós, Jorge García-Piqueras, Benjamín Martín-Biedma, Teresa Cobo, Olivia García-Suárez, José A. Vega
Background The cutaneous end organ complexes or cutaneous sensory corpuscles are specialized sensory organs associated to low-threshold mechanoreceptors. Mechano-gated proteins forming a part of ion channels have been detected in both the axon and terminal glial cells of Meissner corpuscles, a specific cutaneous end organ complex in the human glabrous skin. The main candidates to mechanotransduction
-
In remembrance of Karl M.F. Meller (1937–2023) Ann. Anat. (IF 2.2) Pub Date : 2023-12-13 Pedro Mestres Ventura
Abstract not available
-
Morphological features of the non-affected side of the hindfoot in patients with unilateral varus ankle osteoarthritis Ann. Anat. (IF 2.2) Pub Date : 2023-12-14 Hiroyuki Seki, Shuhei Nozaki, Naomichi Ogihara, Tetsuro Kokubo, Takeo Nagura
Background The innate shape characteristics of the hindfoot bones alter the loading conditions of the foot and thus may be associated with an increased risk of developing varus ankle osteoarthritis (OA). This study aimed to clarify the innate morphological patterns of the hindfoot bones that may be associated with ankle OA by analyzing the differences between the bone morphology of the non-affected
-
Challenges to sourcing human bodies for teaching and research in Africa: Are the challenges insurmountable? Ann. Anat. (IF 2.2) Pub Date : 2023-12-06 Beverley Kramer
The teaching and learning of human anatomy by dissection has existed for thousands of years. Over the centuries, evolving ethical considerations for the sourcing of human bodies for dissection have resulted in a transition from the use of unconsented individuals to that of body donors and the institution of body donation programmes around the world. However, major challenges on the African continent
-
The legal and ethical framework governing body donation in Europe – 2nd update on current practice Ann. Anat. (IF 2.2) Pub Date : 2023-11-30 Erich Brenner, Ronald L.A.W. Bleys, Raffaele de Caro, Ilia Catereniuc, Andy R.M. Chirculescu, Christophe Destrieux, Elisabeth Eppler, Luis Filgueira, David Kachlik, Péter Kiss, Clive Lee, Niki Matveeva, Konstantinos Natsis, Diogo Pais, Friedrich Paulsen, Maria Piagkou, Fabio Quondamatteo, Dóra Reglődi, Erdoğan Şendemir, Jørgen Tranum-Jensen, María Teresa Vázquez Osorio
Background In 2008, members of the TEPARG provided first insights into the legal and ethical framework governing body donation in Europe. In 2012, a first update followed. This paper is now the second update on this topic and tries to extend the available information to many more European countries. Methods For this second update, we have asked authors from all European countries to contribute their
-
Investigation of the variability of the pterygomandibular space from the point of view of the target point of the inferior alveolar nerve block Ann. Anat. (IF 2.2) Pub Date : 2023-12-04 H.M. Darawsheh, N.I. Makarova, I.S. Dydykina, D.A. Lezhnev, M.O. Dobrokhotova, G.T. Saleeva, N.R. Saleev, R.A. Saleev, S.S. Dydykin, Y.L. Vasil’ev
Introduction A thorough knowledge of the anatomy and variability of the pterygomandibular space (PMS) is essential to the success of local anesthesia. This study is aimed at determining the volume of the PMS depending on the shape of the skull, face and mandible using the computed tomography (CT). Materials and methods anonymized computed tomograms of 48 adult patients were analyzed, the indicators
-
VGF modifications related to nigrostriatal dopaminergic neurodegeneration induced by the pesticide fipronil in adult male rats Ann. Anat. (IF 2.2) Pub Date : 2023-12-04 Elias Manca, Barbara Noli, Giulia Corda, Majda El-Hassani, Antonio Manai, Fabrizio Sanna, Antonio Argiolas, Maria Rosaria Melis, Barbara Manconi, Cristina Contini, Cristina Cocco
Background Dopamine is reduced in the brain of rats treated with fipronil, a broad-spectrum insecticide. VGF (no acronym) is a neurotrophin-inducible protein expressed as the 75 kDa form (precursor or pro-VGF) or its truncated peptides. VGF immunostaining has been revealed using an antibody against the C-terminal nonapeptide of the rat pro-VGF in the nerve terminals of the rat substantia nigra, where
-
Three-dimensional analysis of the alveolar ridge profiles of maxillary central incisors in children for autotransplantation Ann. Anat. (IF 2.2) Pub Date : 2023-11-26 Ko Eun Lee, Joon Young Koo, Ju Ri Ye, Yong Kwon Chae, Hyo-Seol Lee, Sung Chul Choi, Ok Hyung Nam
Background Sufficient alveolar housing is fundamental to ensure the favorable prognosis of autotransplanted teeth. However, little is known about the alveolar ridge profiles of the anterior maxilla in children. Therefore, this study aimed to investigate the alveolar ridge profiles of the anterior maxilla in growing children. Methods A total of 169 Korean children aged 10–13 years old were included
-
New insights in the renal distribution profile of TRPC3 – Of mice and men Ann. Anat. (IF 2.2) Pub Date : 2023-11-15 Coline M. Diebolt, Dirk Schaudien, Kerstin Junker, Gabriela Krasteva-Christ, Thomas Tschernig, Colya N. Englisch
Several reports previously investigated the Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects
-
3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats Ann. Anat. (IF 2.2) Pub Date : 2023-11-08 Zeynab Ghorbani, Mojtaba Sani, Zahra Aghighi, Meysam Hassani Moghaddam, Neda Eskandari, Esmaeil Mohammadbagheri, Mobina Fathi, Zahra Shenasandeh, Farid Fotouhi, Mohammad-Amin Abdollahifar, Mina Salehi, Amir-Hossein Bayat, Gholam Hossein Meftahi, Abbas Aliaghaei, Homa Rasoolijazi
3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral
-
Responsible research in the practice of anatomy: Attributes relevant to body donors and human tissues sourced from them Ann. Anat. (IF 2.2) Pub Date : 2023-11-04 Sanjib Kumar Ghosh, Jerzy A. Walocha
Responsible Research involves setting moral examples before fellow academicians and the society as a whole. The concept of Responsible Research applies appropriately to ethical sourcing and handling of human tissues. The present study was undertaken to analyze present situation regarding implementation of attributes of Relevant Research in relation to body donors in anatomical research. A literature
-
Interference of MDM2 attenuates vascular endothelial dysfunction in hypertension partly through blocking Notch1/NLRP3 inflammasome pathway Ann. Anat. (IF 2.2) Pub Date : 2023-11-04 Rongyan Sun, Yubo Zhou, Jiao Liang, Lihong Yang, Zhengjun Fan, Huali Wang
Background Hypertension is a life-threatening disease mainly featured as vascular endothelial dysfunction. This study aims to explore the regulatory role of murine double minute 2 (MDM2) in hypertension and vascular damage. Methods Mice were infused with angiotensin II (AngII) to establish a hypertension mouse model in vivo and AngII-stimulated HUVECs were constructed to simulate the damage of vascular
-
Resveratrol can improve spinal cord injury by activating Nrf2/HO-1 signaling pathway Ann. Anat. (IF 2.2) Pub Date : 2023-10-23 Shi Tang, Benson O.A. Botchway, Yong Zhang, Xichen Wang, Min Huang, Xuehong Liu
-
The advantages of utilizing different ultrasound imaging techniques on joints of human cadavers in the teaching of anatomy – A scoping review Ann. Anat. (IF 2.2) Pub Date : 2023-10-23 Felix Margenfeld, Adib Zendehdel, Giorgio Tamborrini, Magdalena Müller-Gerbl
Background A common approach to define sonoanatomy is a reciprocal exchange of macroscopic and microscopic information in ultrasound imaging. High-resolution ultrasound has been long established and is crucial as an inexpensive and adaptable tool, not just in clinical settings but also while teaching anatomy. Early application of ultrasonography provides medical students with a couple of benefits:
-
The influence of collaborative learning and self-organisation on medical students’ academic performance in anatomy Ann. Anat. (IF 2.2) Pub Date : 2023-10-23 Harald Knof, Markus Berndt, Thomas Shiozawa
Background In 2021, university teaching at the Faculty of Medicine Tuebingen was transferred to a digital setting. Due to the discontinuation of face-to-face teaching, students lacked the temporal and spatial framework of the curriculum and the possibility to socialise with fellow students was extremely limited. Increased demands were placed on the students' self-organisation, and the possibility of
-
The anatomical variability of obturator vessels: Systematic review of literature Ann. Anat. (IF 2.2) Pub Date : 2023-10-20 Zuzana Marvanova, David Kachlik
Objective To systematically assess available information about all variations of obturator vessels and to present the most surgically relevant types, their prevalence and calibre in order to provide a comprehensive overview for both anatomists and clinicians. Materials and methods A total of 2689 studies were found via searching the online databases. After applying exclusion criteria 44 studies were
-
Development of the human primary and secondary jaw joints Ann. Anat. (IF 2.2) Pub Date : 2023-10-22 EM Fernández-Rubio, RJ Radlanski
This study investigates the development of the primary and secondary jaw joints in humans, focusing on their concomitance and subsequent disconnection. Development begins with the primary temporomandibular joint as a connection between Meckel's cartilage and the incus, while the secondary temporomandibular joint develops anteriorly as an articulation between the mandibular condyle and the mandibular
-
Early functional and morphological changes of calf muscles in delayed onset muscle soreness (DOMS) assessed with 7T MRI Ann. Anat. (IF 2.2) Pub Date : 2023-10-21 Rafael Heiss, Svenja A. Höger, Michael Uder, Thilo Hotfiel, Jannis Hanspach, Frederik B. Laun, Armin M. Nagel, Frank W. Roemer
Background To assess morphological and functional alterations of the skeletal muscle in exercise-induced delayed onset muscle soreness (DOMS) using 7 Tesla (T) magnetic resonance imaging (MRI). Methods DOMS was induced in 16 volunteers performing an eccentric exercise protocol of the calf muscles of one randomized leg. 7 T MRI including T1w- (0.18×0.18×1mm3), T2w-images (0.2×0.2×2mm3), T2-maps (0.5×0
-
Clinical anatomy of the spina musculi recti lateralis: A frequently overlooked variation of the greater wing of the sphenoid Ann. Anat. (IF 2.2) Pub Date : 2023-10-14 Denise Bonente, Virginia Barone, Vitaliano Francesco Muzii, Sara Ottolenghi, Miriam Durante, Sandra Bracco, Claudio Nicoletti, Eugenio Bertelli
Background The spina musculi recti lateralis (SMRL) is often visible along the lateral rim of the superior orbital fissure (SOF). Aim of this study is to characterize SMRL morphology and topography relative to known bony landmarks. Methods Orbits from 291 adult dry skulls and from 60 CT scans were analyzed to measure the distance between the SMRL and the SOF or the inferior orbital fissures (IOF) as