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Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-03-30 Yi Wu, Qiwei Qian, Qiaoyan Liu, Rui Wang, Xiting Pu, Yao Li, Huayang Zhang, Zhengrui You, Qi Miao, Xiao Xiao, Min Lian, Qixia Wang, Minoru Nakamura, M. Eric Gershwin, Zhiqiang Li, Xiong Ma, Ruqi Tang
Osteoporosis is a major clinical problem in many autoimmune diseases, including primary biliary cholangitis (PBC), the most common autoimmune liver disease. Osteoporosis is a major cause of fracture and related mortality. However, it remains unclear whether PBC confers a causally risk-increasing effect on osteoporosis. Herein, we aimed to investigate the causal relationship between PBC and osteoporosis
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From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-03-25 Umm E Salma Shabbar Banatwala, Muhammad Moiz Nasir, Reema Javed, Areeba Ahmed, Syed Ali Farhan, Ali Ajam
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Markers of Endothelial Dysfunction in Kawasaki Disease: An Update Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-03-11 Rajni Kumrah, Taru Goyal, Amit Rawat, Surjit Singh
Kawasaki disease (KD) is a medium vessel vasculitis that has a special predilection for coronary arteries. Cardiovascular complications include the development of coronary artery abnormalities (CAAs) and myocarditis. Endothelial dysfunction (ED) is now recognized to be a key component in the pathogenesis of KD and is believed to contribute to the development of CAAs. ED has been evaluated by several
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Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-03-11
Abstract Effective treatment of drug reactions with eosinophilia and systemic symptoms (DReSS) requires early diagnosis and close monitoring. Diagnosing DReSS is especially challenging in children due to a low incidence rate, heterogeneous clinical presentation, and a lack of (pediatric) diagnostic criteria and clinical practice guidelines. We performed a scoping review, according to the Preferred
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B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-03-09
Abstract In the field of contemporary medicine, autoimmune diseases (AIDs) are a prevalent and debilitating group of illnesses. However, they present extensive and profound challenges in terms of etiology, pathogenesis, and treatment. A major reason for this is the elusive pathophysiological mechanisms driving disease onset. Increasing evidence suggests the indispensable role of B cells in the pathogenesis
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Tissue-Resident Memory T Cells in Allergy Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-02-21 Bojin Long, Shican Zhou, Yawen Gao, Kai Fan, Ju Lai, Chunyan Yao, Jingwen Li, Xiayue Xu, Shaoqing Yu
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Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-02-07 Yuhan Xing, Xinmeng Yang, Zhaoyinqian Li, Qiyuan Zou, Ping Yang, Qinzheng Wang, Wei Ni, Dongze Wu, Guoju Li
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A Global View of Pemphigus: Geographical Variations Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-01-30 Rodolfo Pessato Timóteo, Yago Marcos Pessoa-Gonçalves, José Rodrigues do Carmo Neto, Wellington Francisco Rodrigues, Marcos Vinícius da Silva, Carlo José Freire Oliveira
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Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-01-30 Daniel Elieh-Ali-Komi, Ilze Bot, Mónica Rodríguez-González, Marcus Maurer
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Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis? Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-01-29 Kripa Ahuja, Christopher J. Issa, Susan T. Nedorost, Peter A. Lio
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A Comprehensive Review of Sulfonamide Hypersensitivity: Implications for Clinical Practice Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-01-04 Bruno Serrano-Arias, Adriana Araya-Zúñiga, Johan Waterhouse-Garbanzo, Zoe Rojas-Barrantes, Sebastián Arguedas-Chacón, Esteban Zavaleta-Monestel
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Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2024-01-04
Abstract Chronic rhinosinusitis (CRS) is a highly heterogeneous disease characterized by inflammation in the nasal and sinus mucosa. The CRS phenotypes, based on the presence or absence of nasal polyps, are known as CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). However, this classification has limitations in fully capturing the mechanisms and clinical manifestations of CRS.
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Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-12-29 Nicoletta Luciano, Elisa Barone, Suraj Timilsina, M. Eric Gershwin, Carlo Selmi
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Autoinflammatory Keratinization Diseases—The Concept, Pathophysiology, and Clinical Implications Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-12-16
Abstract Recent advances in medical genetics elucidated the background of diseases characterized by superficial dermal and epidermal inflammation with resultant aberrant keratosis. This led to introducing the term autoinflammatory keratinization diseases encompassing entities in which monogenic mutations cause spontaneous activation of the innate immunity and subsequent disruption of the keratinization
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Eosinophil-Associated Gastrointestinal Manifestations During OIT Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-11-14 Michael R. Goldberg, Naama Epstein-Rigbi, Arnon Elizur
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A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency—Real-World Data Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-11-02 Felix Johnson, Anna Stenzl, Benedikt Hofauer, Helen Heppt, Eva-Vanessa Ebert, Barbara Wollenberg, Robin Lochbaum, Janina Hahn, Jens Greve, Susanne Trainotti
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Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-10-28 Hsuan-Chi Chen, Chuang-Wei Wang, Wu Han Toh, Hua-En Lee, Wen-Hung Chung, Chun-Bing Chen
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Vernal Keratoconjunctivitis: A Systematic Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-09-02 Gaia Bruschi, Daniele Giovanni Ghiglioni, Laura Cozzi, Silvia Osnaghi, Francesco Viola, Paola Marchisio
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Treatable Traits in Systemic Sclerosis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-08-21 Francesco Amati, Gabriele Bongiovanni, Antonio Tonutti, Francesca Motta, Anna Stainer, Giuseppe Mangiameli, Stefano Aliberti, Carlo Selmi, Maria De Santis
Systemic sclerosis (SSc) is a chronic systemic disease within the spectrum of connective tissue diseases, specifically characterized by vascular abnormalities and inflammatory and fibrotic involvement of the skin and internal organs resulting in high morbidity and mortality. The clinical phenotype of SSc is heterogeneous, and serum autoantibodies together with the extent of skin involvement have a
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Hypersensitivity Reactions to Taxanes: A Comprehensive and Systematic Review of the Efficacy and Safety of Desensitization Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-08-17 Rosalaura Virginia Villarreal-González, Sandra González-Díaz, Oscar Vidal-Gutiérrez, Alejandra Canel-Paredes, Carlos de la Cruz-de la Cruz, Mariano García-Campa, Alfonso López-Méndez, Sofía Alvarado-Ruiz, Mariana Castells
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Shared Pathogenicity Features and Sequences between EBV, SARS-CoV-2, and HLA Class I Molecule-binding Motifs with a Potential Role in Autoimmunity Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-07-28 Yekbun Adiguzel, Naim Mahroum, Sylviane Muller, Miri Blank, Gilad Halpert, Yehuda Shoenfeld
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Environmental Risk Factors, Protective Factors, and Biomarkers for Allergic Rhinitis: A Systematic Umbrella Review of the Evidence Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-07-25 Xianpeng Xu, Xinghong Liu, Jiongke Li, Xinxing Deng, Tianrong Dai, Qingjie Ji, Dajing Xiong, Hui Xie
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γδ T Cells and Allergic Diseases Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-07-03 Uei-Hsiang Hsu, Bor-Luen Chiang
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During Sepsis and COVID-19, the Pro-Inflammatory and Anti-Inflammatory Responses Are Concomitant Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-07-03 Jean-Marc Cavaillon
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COVID-19, Coronavirus Vaccines, and Possible Association with Lipschütz Vulvar Ulcer: A Systematic Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-06-26 Stefano A. Vismara, Andrea Ridolfi, Pietro B. Faré, Mario G. Bianchetti, Sebastiano A. G. Lava, Samuele Renzi, Benedetta Terziroli Beretta Piccoli, Gregorio P. Milani, Lisa Kottanattu
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Perspectives on Mycophenolate Mofetil in the Management of Autoimmunity Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-06-20 Rithika Bhat, Antonio Tonutti, Suraj Timilsina, Carlo Selmi, M. Eric Gershwin
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Food Allergy Labeling Laws: International Guidelines for Residents and Travelers Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-05-09 Francesca Chang, Lauren Eng, Christopher Chang
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Single-Cell Analysis of Patients with Axial Spondyloarthritis After Anti-TNFα Treatment: Experimental Data and Review of the Literature Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-03-08 Zhi-Bin Zhao, Zhen-Hua Bian, Zhang-Mei Lin, Shu-Fan Wu, Jie Long, Yang Cui, Yang Li, Wende Li, Er-Wei Sun, Zhe-Xiong Lian, Yi He
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Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-02-28 Zhouxian Pan, Yimin Dai, Nicole Akar-Ghibril, Jessica Simpson, Huali Ren, Lishan Zhang, Yibo Hou, Xueyi Wen, Christopher Chang, Rui Tang, Jin-Lyu Sun
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The Evolving Landscape of Fecal Microbial Transplantation Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2023-02-09 Tihong Shao, Ronald Hsu, Camelia Hacein-Bey, Weici Zhang, Lixia Gao, Mark J. Kurth, Huanhuan Zhao, Zongwen Shuai, Patrick S. C. Leung
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Epigenetic Dysregulation in Autoimmune and Inflammatory Skin Diseases Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-11-08 Frederick Gibson, Ailish Hanly, Nicole Grbic, Noah Grunberg, Muzhou Wu, Marianne Collard, Rhoda M. Alani
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New Mechanistic Advances in FcεRI-Mast Cell–Mediated Allergic Signaling Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-10-17 Yang Li, Patrick S. C. Leung, M. Eric Gershwin, Junmin Song
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Systemic Sclerosis Association with Malignancy Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-09-19 Gemma Lepri, Martina Catalano, Silvia Bellando-Randone, Serena Pillozzi, Elisa Giommoni, Roberta Giorgione, Cristina Botteri, Marco Matucci-Cerinic, Lorenzo Antonuzzo, Serena Guiducci
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Hair Follicle Melanocytes Initiate Autoimmunity in Alopecia Areata: a Trigger Point Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-09-19 Bo Xie, Jiayi Sun, Xiuzu Song
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The Genetics of Eczema Herpeticum Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-09-17 Elisabeth Hodara, Peck Y. Ong
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Pathophysiology, Diagnosis, and Management of Chronic Spontaneous Urticaria: A Literature Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-09-01 Benjamin Greiner, Savannah Nicks, Michael Adame, Jennifer McCracken
Chronic spontaneous urticaria (CSU) is characterized by recurring wheals that last 6 weeks or longer without an identifiable cause. The estimated point prevalence of CSU worldwide is 1%. Furthermore, it has a significant impact on quality of life in both adults and pediatric patients and their families. Although it is most often a self-limited disease, some patients have urticaria refractory to first-line
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The Treatment of Primary Immune Deficiencies: Lessons Learned and Future Opportunities Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-07-01 Kenneth Paris, Luke A. Wall
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A Summary on the Genetics of Systemic Lupus Erythematosus, Rheumatoid Arthritis, Systemic Sclerosis, and Sjögren’s Syndrome Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-24 Lourdes Ortíz-Fernández, Javier Martín, Marta E. Alarcón-Riquelme
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Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-18 Ilaria Cavazzana, Tamara Vojinovic, Paolo Airo’, Micaela Fredi, Angela Ceribelli, Eleonora Pedretti, Maria Grazia Lazzaroni, Emirena Garrafa, Franco Franceschini
Disease-specific autoantibodies are considered the most important biomarkers for systemic sclerosis (SSc), due to their ability to stratify patients with different severity and prognosis. Anti-nuclear antibodies (ANA), occurring in subjects with isolated Raynuad’s phenomenon, are considered the strongest independent predictors of definite SSc and digital microvascular damage, as observed by nailfold
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Inflammaging and Osteoarthritis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-18 Francesca Motta, Elisa Barone, Antonio Sica, Carlo Selmi
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T Cell Abnormalities in X-Linked Agammaglobulinaemia: an Updated Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-16 Sanchi Chawla, Ankur Kumar Jindal, Kanika Arora, Rahul Tyagi, Manpreet Dhaliwal, Amit Rawat
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Correlates of Protection Against Respiratory Syncytial Virus Infection in Infancy Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-11 Bahaa Abu-Raya, Frederic Reicherz, Pascal M. Lavoie
The highest morbidity and mortality from respiratory syncytial virus (RSV) infection occurs in young infants. Immunization of expectant mothers during pregnancy has the potential to substantially reduce the burden of RSV disease in a majority of infants. Correlates of protection (COP) are important in guiding the development of maternal RSV vaccines and the design of maternal RSV vaccine trials, as
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Germinal Center-Related G Protein-Coupled Receptors in Antibody-Mediated Autoimmune Skin Diseases: from Basic Research to Clinical Trials Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-08 Pengpeng Cao, Ming Yang, Christopher Chang, Haijing Wu, Qianjin Lu
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Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-03 Mingli Hu, Zhengrui You, You Li, Bingyuan Huang, Nana Cui, Rui Wang, Yiran Wei, Bo Li, Jubo Liang, Qiaoyan Liu, Yikang Li, Hanxiao Wang, Qiwei Qian, Jun Zhang, Ruiling Chen, Zhuwan Lyu, Yong Chen, Xiao Xiao, Min Lian, Ruqi Tang, Qi Miao, Qixia Wang, Xiong Ma
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Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-01 Tracy Augustine, Manoj Kumar, Souhaila Al Khodor, Nicholas van Panhuys
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Autoimmunity in Primary Immunodeficiencies (PID) Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-01 Grace T. Padron, Vivian P. Hernandez-Trujillo
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Renal Disease and Systemic Sclerosis: an Update on Scleroderma Renal Crisis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-06-01 Alice Cole, Voon H. Ong, Christopher P. Denton
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Autoantibodies and Cancer Association: the Case of Systemic Sclerosis and Dermatomyositis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-05-20 David F. Fiorentino, Livia Casciola-Rosen
Several rheumatic diseases have a perplexing association with cancer. Unraveling this mysterious connection is likely to provide deeper understanding regarding mechanisms governing the onset of both autoimmunity and cancer immunity, in addition to providing clinicians much needed guidance around whom and when to screen for occult malignancy. Systemic sclerosis (scleroderma) and dermatomyositis are
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Inflammaging and Frailty in Immune-Mediated Rheumatic Diseases: How to Address and Score the Issue Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-05-21 Fausto Salaffi, Andrea Di Matteo, Sonia Farah, Marco Di Carlo
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Infections or Vaccines Associated with Finkelstein-Seidlmayer Vasculitis: Systematic Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-05-12 Gabriel Bronz, Céline Betti, Pietro O. Rinoldi, Lisa Kottanattu, Mario G. Bianchetti, Danilo Consolascio, Marcel M. Bergmann, Gregorio P. Milani, Benedetta Terziroli Beretta Piccoli, Sebastiano A. G. Lava
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Allergy to Local Anesthetics is a Rarity: Review of Diagnostics and Strategies for Clinical Management Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-04-28 Shirley Jiang, Monica Tang
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Real-Life Effectiveness of Benralizumab, Mepolizumab and Omalizumab in Severe Allergic Asthma Associated with Nasal Polyps Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-04-14 Angelica Tiotiu, Paula Mendez-Brea, Iulia Ioan, Rodrigo Romero-Fernandez, Jean Philippe Oster, Thi-cam-tu Hoang, Pauline Roux, Diana Carolina Ochoa-Gutierrez, Philippe Bonniaud, Frederic de Blay, Francisco-Javier Gonzalez-Barcala
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Thoracic Involvement in Systemic Autoimmune Rheumatic Diseases: Pathogenesis and Management Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-18 Elena De Zorzi, Paolo Spagnolo, Elisabetta Cocconcelli, Elisabetta Balestro, Luca Iaccarino, Mariele Gatto, Francesco Benvenuti, Nicol Bernardinello, Andrea Doria, Toby M. Maher, Elisabetta Zanatta
Thoracic involvement is one of the main determinants of morbidity and mortality in patients with autoimmune rheumatic diseases (ARDs), with different prevalence and manifestations according to the underlying disease. Interstitial lung disease (ILD) is the most common pulmonary complication, particularly in patients with systemic sclerosis (SSc), idiopathic inflammatory myopathies (IIMs) and rheumatoid
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Diagnostic Modalities in Primary Immunodeficiency Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-15 Loveita S. Raymond, Jennifer Leiding, Lisa R. Forbes-Satter
As the field of inborn errors of immunity expands, providers continually update and fine-tune their diagnostic approach and selection of testing modalities to increase diagnostic accuracy. Here, we first describe a mechanistic consideration of laboratory testing, highlighting both benefits and drawbacks of currently clinically available testing modalities. Next, we provide methods in evaluation of
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The Airway Microbiome-IL-17 Axis: a Critical Regulator of Chronic Inflammatory Disease Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-11 Jenny M. Mannion, Rachel M. McLoughlin, Stephen J. Lalor
The respiratory tract is home to a diverse microbial community whose influence on local and systemic immune responses is only beginning to be appreciated. Increasing reports have linked changes in this microbiome to a range of pulmonary and extrapulmonary disorders, including asthma, chronic obstructive pulmonary disease and rheumatoid arthritis. Central to many of these findings is the role of IL-17-type
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Dupilumab-Associated Adverse Events During Treatment of Allergic Diseases Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-11 Anna Kychygina, Myriam Cassagne, Marie Tauber, Stéphane Galiacy, Carle Paul, Pierre Fournié, Michel Simon
Among the new biological therapies for atopic diseases, dupilumab is a fully human monoclonal antibody directed against IL-4Rα, the common chain of interleukin-4 and interleukin-13 receptors. Dupilumab showed clinical improvements in patients with atopic dermatitis, asthma, and chronic rhinosinusitis and is currently under development for other indications. While dupilumab is considered to be well
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Clinical Significance of Antinucleolar Antibodies: Biomarkers for Autoimmune Diseases, Malignancies, and others Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-08 Minoru Satoh, Angela Ceribelli, Tomoko Hasegawa, Shin Tanaka
Nucleolar staining is one of the standard patterns in immunofluorescence antinuclear antibodies (ANA), seen in 5–9% of ANA in various conditions. Antinucleolar antibodies (ANoA) are classified into 3 patterns in the International Consensus on ANA Patterns (ICAP) classification; AC-8 homogeneous pattern, AC-9 clumpy pattern, and AC-10 punctate pattern. Specificities known to show AC-8 include anti-Th/To
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Premedication Protocols to Prevent Hypersensitivity Reactions to Chemotherapy: a Literature Review Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-08 Faisal ALMuhizi, Leticia De Las Vecillas Sanchez, Lucy Gilbert, Ana M. Copaescu, Ghislaine A. C. Isabwe
Hypersensitivity reactions (HSRs) to chemotherapy may prevent patients from receiving the most effective therapy. This review was undertaken to identify evidence-based preventive premedication strategies that reduce the likelihood of HSR in the first instance and improve the safety of subsequent infusions in patients who have demonstrated HSR to a certain class of chemotherapy. PubMed was searched
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A Narrative Review of Pathogenetic and Histopathologic Aspects, Epidemiology, Classification Systems, and Disease Outcome Measures in Systemic Sclerosis Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-07 Maria-Grazia Lazzaroni, Silvia Piantoni, Fabrizio Angeli, Stefania Bertocchi, Franco Franceschini, Paolo Airò
Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by the presence of three main actors: vasculopathy, immune activation, and fibrosis. This pathologic process is then translated in a clinical picture with great variability among different patients in terms of type of organ involvement, disease severity and prognosis. This heterogeneity is a main feature of SSc, which, in
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The Role of Autoantibody Testing in Modern Personalized Medicine Clinic. Rev. Allerg Immunol. (IF 9.1) Pub Date : 2022-03-04 Cristiane Kayser, Lívia Almeida Dutra, Edgard Torres dos Reis-Neto, Charlles Heldan de Moura Castro, Marvin J. Fritzler, Luis Eduardo C. Andrade
Personalized medicine (PM) aims individualized approach to prevention, diagnosis, and treatment. Precision Medicine applies the paradigm of PM by defining groups of individuals with akin characteristics. Often the two terms have been used interchangeably. The quest for PM has been advancing for centuries as traditional nosology classification defines groups of clinical conditions with relatively similar