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Differential tempol effects in prostatic cancer: angiogenesis and short- and long-term treatments J. Mol. Hist. (IF 3.2) Pub Date : 2024-03-29 Felipe Rabelo Santos, Isabela Maria Urra Rossetto, Fabio Montico, Celina de Almeida Lamas, Valéria Helena Alves Cagnon
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New insights into the treatment of polycystic ovary syndrome: HKDC1 promotes the growth of ovarian granulocyte cells by regulating mitochondrial function and glycolysis J. Mol. Hist. (IF 3.2) Pub Date : 2024-03-13 Peiwei Cong, Bing Shang, Lina Zhang, Zhaoli Wu, Yanan Wang, Jia Li, Lin Zhang
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Quercetin promotes ATG5-mediating autophagy-dependent ferroptosis in gastric cancer J. Mol. Hist. (IF 3.2) Pub Date : 2024-03-05 Ju Huang, Jian Chen, Jingnan Li
Quercetin has been documented to possess a multitude of pharmacological effects, encompassing antioxidant, antiviral, antimicrobial, and anti-inflammatory properties. Nevertheless, the exact molecular mechanisms responsible for the anti-tumor properties of quercetin remain to be fully explicated. To this end, quercetin was administered to gastric cancer cells (in vitro) AGS and MKN45, as well as BALB/c
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Regulatory role of N-myc downregulated genes in amelogenesis in rats J. Mol. Hist. (IF 3.2) Pub Date : 2024-02-26
Abstract Cytodifferentiation of odontogenic cells, a late stage event in odontogenesis is based on gene regulation. However, studies on the identification of the involved genes are scarce. The present study aimed to search for molecules for the cytodifferentiation of ameloblastic cells in rats. Differential display-PCR revealed a differentially expressed gene between cap/early bell stage and hard tissue
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Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice J. Mol. Hist. (IF 3.2) Pub Date : 2024-02-20 Jian Zeng, Qiong-Qiong Lu, Xiao-Long Du, Ling Yuan, Xiao-Jun Yang
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BLVRA exerts its biological effects to induce malignant properties of hepatocellular carcinoma cells via Wnt/β-catenin pathway J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-13
Abstract The function of Biliverdin Reductase A (BLVRA) in hepatocellular carcinoma (HCC) cells proliferation, invasion and migration remains unclear. Therefore, this research intends to explore the effect of BLVRA on HCC cells growth and metastasis. BLVRA expression was analyzed in public dataset and examined by using western blot. The malignant function of BLVRA in HCC cell lines and its effect on
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The lncRNA lnc-TSI antagonizes sorafenib resistance in hepatocellular carcinoma via downregulating miR-4726-5p expression and upregulating KCNMA1 expression J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Fengrong Chen, Jiong Jiang, Dong Liu, Hong Li, Lei Dong, Yahua Song, Ying Zhang, Jing Wang, Yun Qin, Gang Zhao
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Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Yuanxing Han, Nueryemu Maimaiti, Yue Sun, Juan Yao
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Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Xiaoting Xi, Qianbo Chen, Jia Ma, Xuewei Wang, Junyan Zhang, Yan Li
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VNS improves VSMC metabolism and arteriogenesis in infarcted hearts through m/n-AChR-Akt-SDF-1α in adult male rats J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02
Abstract Vagal nerve stimulation (VNS) provides a novel therapeutic strategy for injured hearts by activating cholinergic anti-inflammatory pathways. However, little information is available on the metabolic pattern and arteriogenesis of VSMCs after MI. VNS has been shown to stimulate the expression of CPT1α, CPT1β, Glut1, Glut4 and SDF-1α in coronary VSMCs, decreasing the number of CD68-positive macrophages
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Orientin alleviates ox-LDL-induced oxidative stress, inflammation and apoptosis in human vascular endothelial cells by regulating Sestrin 1 (SESN1)-mediated autophagy J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou
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Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Lin Li, Liuyan Xin, Xiang Yang, Zhengrong Zou
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Silenced-C5ar1 improved multiple organ injury in sepsis rats via inhibiting neutrophil extracellular trap J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Bin Shen, Qikai Shen, Qingqiu Zeng, Lingyan Zhang, Xiaofeng Li
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TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Rafaela C. Perez, Xenia Yang, Mary Familari, Gemma Martinez, Frank J. Lovicu, Gary R Hime, Robb U de Iongh
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Overview of the compromised mucosal integrity in celiac disease J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Tannaz Taraz, Mohadeseh Mahmoudi-Ghehsareh, Nastaran Asri, Ehsan Nazemalhosseini-Mojarad, Mostafa Rezaei-Tavirani, Somayeh Jahani-Sherafat, Ali Naseh, Mohammad Rostami-Nejad
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LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling J. Mol. Hist. (IF 3.2) Pub Date : 2024-01-02 Yao Wang, Hongfei Tong, Juxiang Wang, Linglong Hu, Zhen Huang
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LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-30 Bangsheng Chen, Lian Tan, Ying Wang, Lei Yang, Jiequan Liu, Danqi Chen, Shuaishuai Huang, Feiyan Mao, Jiangfang Lian
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Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-25 Xiaoyu Zhu, Jie Ji, Xiaodong Han
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Mitochondria as a target for exercise-mitigated type 2 diabetes J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-24 Jingjing Tian, Jingcheng Fan, Tan Zhang
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Effects of abnormal expression of CD73 on malignant phenotype of nasopharyngeal carcinoma J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-24 Bin Jiang, Mingming Tang, Si Shi, Haijing Xie, Si Pan, Lin Zhang, Juping Sheng
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Investigation of miR-26b and miR-27b expressions and the effect of quercetin on fibrosis in experimental pulmonary fibrosis J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-19 Çağrı Toker, Yurdun Kuyucu, Dilek Şaker, Samet Kara, Bilge Güzelel, Ufuk Özgü Mete
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The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-19 Qianzi Liu, Minxuan Yu, Menglin Liao, Zhiyue Ran, Xiaofeng Tang, Jun Hu, Beiju Su, Gang Fu, Qingqing Wu
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The circSNX14 functions as a tumor suppressor via the miR-562/ LATS2 pathway in hepatocellular carcinoma cells J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-20 Yan Wu, Yaowei Yang, Xin Yi, Liwen Song
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Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-17 Jun Pan, Youzhi Cai, Chi Zhang, Sanzhong Xu
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Serum HBV RNA levels among untreated adults with chronic hepatitis B in distinct immune phases and liver histopathology statuses J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-16 Qin Xu, Hai Ding, Tao Bai, Rui Huang, Jian Wang, Jun Zhang, Hewei Luan, Jun Wang, Yue Yang, Yuxin Chen
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Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-13 Zheng Li, Weiwei Zhang, Ji Xu, Xiaoye Mo
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ERO1α promotes the proliferation and inhibits apoptosis of colorectal cancer cells by regulating the PI3K/AKT pathway J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-30 Min Wu, Ruixue Li, Jianyan Qin, Ziyuan Wang, Jiasen Guo, Fenghong Lv, Guoqin Wang, Youguang Huang
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Dynamic patterns of histone lactylation during early tooth development in mice J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-03 Ming Liu, Qian Yang, Huanyan Zuo, Xinye Zhang, Yuji Mishina, Zhi Chen, Jingwen Yang
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Correction to: YTHDF2 negatively correlates with tumor immune infiltration in small cell lung cancer. J. Mol. Hist. (IF 3.2) Pub Date : 2023-10-01 Gang Chen,Dandan Ren,Yuanhan Wang,Hui Wang,Song Yang,Junhong Zhang
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DLK1 overexpression improves sepsis-induced cardiac dysfunction and fibrosis in mice through the TGF-β1/Smad3 signaling pathway and MMPs J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-28 Ni Zeng, Zaijin Jian, Junmei Xu, Sijia Zheng, Yongmei Fan, Feng Xiao
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MicroRNA-495: a therapeutic and diagnostic tumor marker J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-28 Amirhosein Maharati, Faezeh Tolue Ghasaban, Iman Akhlaghipour, Negin Taghehchian, Amir Sadra Zangouei, Meysam Moghbeli
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USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-27 Wanlin Zhu, Bin Ye, Shangwen Yang, Youming Li
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Three-dimensional visualization of the lymphatic, vascular and neural network in rat lung by confocal microscopy J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-27 Shitong Zhao, Jingjing Cui, Yuqing Wang, Dongsheng Xu, Yuxin Su, Jie Ma, Xuefeng Gong, Wanzhu Bai, Jia Wang, Rui Cao
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Sennoside A induces autophagic death of prostate cancer via inactivation of PI3K/AKT/mTOR axis J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-23 Shaoyi Qiao, Wuhe Zhang, Yao Jiang, Yansheng Su
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The role of HIF-1α-mediated autophagy in ionizing radiation-induced testicular injury J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-20 Renfeng Xu, Siting Shen, Defan Wang, Jianqing Ye, Shiting Song, Zhengchao Wang, Zhicao Yue
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Exercise preconditioning promotes myocardial GLUT4 translocation and induces autophagy to alleviate exhaustive exercise-induced myocardial injury in rats J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-15 Yuan-Pan Guo, Shan-Shan Pan, Tian-Ran Chen, Yue Huang, Dong-Feng Wan, Yi-Shan Tong
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J147 ameliorates sepsis-induced depressive-like behaviors in mice by attenuating neuroinflammation through regulating the TLR4/NF-κB signaling pathway J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-07 Fang Qiu, Changchun Zeng, Yuqiang Liu, Haobo Pan, Changneng Ke
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Knockdown of long non-coding RNA LINC01123 plays a molecular sponge on miR-625-5p to inhibit the process of colorectal cancer cells via LASP1 J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-07 Tao Shang, Shikai Pang, Yunfei Dong
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FGF1 reduces cartilage injury in osteoarthritis via regulating AMPK/Nrf2 pathway J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-02 Yun-Xuan Li, Jun Shu, Nan-nan Kou, Han-Bo Chen, Li-Min Guo, Yong Yuan, Shao-Xuan He, Gang Zhao
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ETV5 transcriptionally activates TGFβ1 and promotes cancer cell invasion and migration of NSCLC J. Mol. Hist. (IF 3.2) Pub Date : 2023-09-01 Dan Li, Yanwei Shen, Hui Ren, Li Wang, Jin Yang, Yuan Wang
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CISD2 transcriptional activated by transcription factor E2F7 promotes the malignant progression of cervical cancer J. Mol. Hist. (IF 3.2) Pub Date : 2023-08-24 Lingling Wang, Yan Wang, Caizhi Wang, Kang Yang, Guoliu Ye
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P53 and VEGF are promising biomarkers for sorafenib efficacy in an experimental model of NASH-related HCC J. Mol. Hist. (IF 3.2) Pub Date : 2023-08-21 João Pedro Nassar-Reis, Pedro Fukui Umeta, José Tadeu Stefano, Adhemar Longatto-Filho, Flair José Carrilho, Venâncio Avancini Ferreira Alves, Bruno Cogliati, Claudia P. Oliveira
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Environmentally relevant DEHP exposure during gestational and lactational period inhibits filamin a testicular expression J. Mol. Hist. (IF 3.2) Pub Date : 2023-08-12 Pablo A. Pérez, Jonathan Toledo, Facundo Vitellini, Victoria Navall Cuello, Verónica Cantarelli, Marina Ponzio, Jorge H. Mukdsi, Silvina Gutiérrez
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Long non coding RNAs reveal important pathways in childhood asthma: a future perspective J. Mol. Hist. (IF 3.2) Pub Date : 2023-08-04 Vahid Goodarzi, Shadi Nouri, Zohre Saleh Nassaj, Mansoureh Bighash, Sadegh Abbasian, Rozita adldoosti Hagh
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The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats J. Mol. Hist. (IF 3.2) Pub Date : 2023-07-27 Xin Zhang, Ying Zhou, Qiongxia Liu, Fang Wang, Lin Fu, Yizhi Wei, Yuanliang Ye, Yujie Guo
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Correction to: Lack of Rab27a attenuates foam cell formation and macrophage inflammation in uremic apolipoprotein E knockout mice J. Mol. Hist. (IF 3.2) Pub Date : 2023-07-14 Yan Shen, Yajuan Gao, Jiani Fu, Cui Wang, Yali Tang, Shengnan Chen, Yan Zhao
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Granulocyte-colony stimulating factor ameliorates di-ethylhexyl phthalate-induced cardiac muscle injury via stem cells recruitment, Desmin protein regulation, antifibrotic and antiapoptotic mechanisms J. Mol. Hist. (IF 3.2) Pub Date : 2023-07-10 Shaimaa A. Abdelrahman, Maha A. Khattab, Marian S. Youssef, Abeer A. Mahmoud
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Differential histological features and myogenic protein levels in distinct muscles of d-sarcoglycan null muscular dystrophy mouse model J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-26 Carlos Palma-Flores, Luis Javier Cano-Martínez, Francisca Fernández-Valverde, Itzel Torres-Pérez, Sergio de los Santos, J. Manuel Hernández-Hernández, Adriana Fabiola Hernández-Herrera, Silvia García, Patricia Canto, Alejandro Zentella-Dehesa, Ramón Mauricio Coral-Vázquez
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Structural and molecular changes in the rat myocardium following perfluoroctane sulfonate (PFOS) exposure are mitigated by quercetin via modulating HSP 70 and SERCA 2 J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-27 Dalia A. Mandour, Manal M. Morsy, Amal Fawzy, Noura Mostafa Mohamed, Marwa M. Ahmad
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Fam20C overexpression in odontoblasts regulates dentin formation and odontoblast differentiation J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-26 Kohei Naniwa, Katsutoshi Hirose, Yu Usami, Kenji Hata, Rikita Araki, Narikazu Uzawa, Toshihisa Komori, Satoru Toyosawa
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YTHDF2 negatively correlates with tumor immune infiltration in small cell lung cancer J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-26 Gang Chen, Dandan Ren, Yuanhan Wang, Hui Wang, Junhong Zhang, Song Yang
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Expressions of Notch signalling pathway members during early pregnancy in mice J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-21 Nuray Acar, Hakan Soylu, Sema Avci, Ismail Ustunel
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Knockdown of USF2 inhibits pyroptosis of podocytes and attenuates kidney injury in lupus nephritis J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-21 Ying Xie, Xiaoying Li, Wenli Deng, Nan Nan, Huimei Zou, Lei Gong, Min Chen, Jie Yu, Peilei Chen, Daolin Cui, Fan Zhang
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CORM-3 alleviates the intestinal injury in a rodent model of hemorrhage shock and resuscitation: roles of GFAP-positive glia J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-19 Li-Min Zhang, Yue Xin, Rong-Xin Song, Wei-Chao Zheng, Jin-Shu Hu, Jie-Xia Wang, Zhi-You Wu, Dong-Xue Zhang
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Lobe-specific responses of TRAMP mice dorsolateral prostate following celecoxib and nintedanib therapy J. Mol. Hist. (IF 3.2) Pub Date : 2023-06-19 Fabio Montico, Celina de Almeida Lamas, Isabela Maria Urra Rossetto, Andressa Mara Baseggio, Valéria Helena Alves Cagnon
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EGF-receptor phosphorylation and downstream signaling are activated by genistein during subacute liver damage J. Mol. Hist. (IF 3.2) Pub Date : 2023-05-25 Erick Ayala-Calvillo, Lourdes Rodríguez-Fragoso, Elizabeth Álvarez-Ayala, Alfonso Leija-Salas
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NeuN distribution in brain structures of normal and Zika-infected suckling mice J. Mol. Hist. (IF 3.2) Pub Date : 2023-05-18 Gerardo Santamaría, Aura Caterine Rengifo, Orlando Torres-Fernández
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Lack of Rab27a attenuates foam cell formation and macrophage inflammation in uremic apolipoprotein E knockout mice J. Mol. Hist. (IF 3.2) Pub Date : 2023-05-11 Yan Shen, Yajuan Gao, Jiani Fu, Cui Wang, Yali Tang, Shengnan Chen, Yan Zhao
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Circadian regulation of mTORC1 signaling via Per2 dependent mechanism disrupts folliculogenesis and oocyte maturation in female mice J. Mol. Hist. (IF 3.2) Pub Date : 2023-05-10 Gizem Bora, Tuğçe Önel, Ecem Yıldırım, Aylin Yaba
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Administration of necrostatin-1 ameliorates glucocorticoid-induced osteonecrosis of the femoral head in rats J. Mol. Hist. (IF 3.2) Pub Date : 2023-05-09 Min Feng, Ruirui Zhang, Mingming Zhang, Ming Chen, Le Ji, Dapeng Duan, Hui Qiang