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HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-19 Lea Saab, Daniel DiCapua, Adeel S. Zubair
HTLV-1 is a retrovirus virus that infects CD4+ T cells. Most people with HTLV-1 infection remain asymptomatic but some may develop conditions such as HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) or adult T-cell leukemia/lymphoma. HAM/TSP is characterized by progressive spasticity and weakness of the lower extremities, as well as loss of bladder control and sensory disturbances
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Timing initiation of non-invasive ventilation in management of ALS J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-19 Michael Swash
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Remote pulmonary function testing allows for early identification of need for non-invasive ventilation in a subset of persons with ALS J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-19 Andrew Geronimo, Zachary Simmons
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Stroke occurrence by hypertension treatment status in Ghana and Nigeria: A case-control study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-17 Fred Stephen Sarfo, Osahon Jeffery Asowata, Onoja Matthew Akpa, Joshua Akinyemi, Kolawole Wahab, Arti Singh, Albert Akpalu, Priscilla Abrafi Opare-Addo, Akinkunmi Paul Okekunle, Godwin Ogbole, Adekunle Fakunle, Oladimeji Adebayo, Reginald Obiako, Cynthia Akisanya, Morenkeji Komolafe, Taiwo Olunuga, Innocent I. Chukwuonye, Godwin Osaigbovo, Paul Olowoyo, Phillip B. Adebayo, Carolyn Jenkins, Abiodun
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Differential diagnosis between multiple sclerosis and leukodystrophies – A scoping review J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-16 Luis Eduardo Ramos Chaer, Jakeline Martins de Mendonça, Maria Cristina del Negro, Ricardo Titze-de-Almeida, Nícolas Philippe Balduino Nogueira, Priscila Mara Provetti, Pedro Renato de Paula Brandão, Diógenes Diego de Carvalho Bispo, Gabriela Billafan Ferreira, Ingrid Faber, Taina Barreto Cavalcante, Tarso Adoni, Juliana F. Mazzeu, Felipe von Glehn
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A case series of post-infectious chikungunya myeloradiculoneuropathy J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-14 Suresh Selvam, Padma Youron, Harpreet Singh, Ritushree, Vikas Suri, Manoj Goyal, Manish Modi, Ashish Bhalla
Chikungunya fever is an arboviral illness transmitted by mosquito bite of and caused by chikungunya virus (CHIKV). It is an RNA virus belonging to the genus Alphavirus and family Togaviridae. We present a case series of three patients with chikungunya illness developing para/post-infectious myeloradiculoneuropathy.These patients developed neurological symptoms in the form of bilateral lower limb weakness
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Diagnostic value of vietnamese smell identification test in Parkinson's disease J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-12 Thuong Huyen Thi Dang, Tai Ngoc Tran, Frank Xing, Uyen Le Ngoc Ha, Khang Chung Ngoc Vo, Thanh Vinh Nguyen, Khang Vinh Nguyen, Hien Thi Le, Daniel Truong
Vietnamese Smell Identification Test (VSIT) has been validated in determining olfactory dysfunction in the Vietnamese population, however its value in diagnosing Parkinson's disease (PD) has not been established. This case-control study was conducted at University Medical Center HCMC, Ho Chi Minh City, Vietnam. The study sample included non-demented PD patients and healthy controls (HC) who were gender-
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Technical and clinical outcomes of thrombectomy in patients with acute medium vessel occlusion and large vessel occlusion; sub-analyses of Japan Trevo registry J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-12 Shuntaro Kuwahara, Kazutaka Uchida, Nobuyuki Sakai, Hiroshi Yamagami, Hirotoshi Imamura, Masataka Takeuchi, Manabu Shirakawa, Fumihiro Sakakibara, Koichi Haraguchi, Naoto Kimura, Kentaro Suzuki, Shinichi Yoshimura, Japan Trevo Registry Investigators
Little is known about endovascular therapy (EVT) for patients with medium vessel occlusion (MeVO) and more work is needed to establish its efficacy and to understand hemorrhagic complications. We analyzed the Japan Trevo Registry, which enrolled patients with acute stroke who underwent EVT using Trevo Retriever alone or in combination with an aspiration catheter. The primary outcome was effective reperfusion
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Chronic inflammatory demyelinating polyneuropathy and HEV antibody status: A case-control study from Lazio, Italy J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-12 Federica Moret, Enea Spada, Marco Ceccanti, Laura Libonati, Edoardo D'Andrea, Umbertina Villano, Elisabetta Madonna, Paola Chionne, Alberto Carocci, Giulio Pisani, Laura Fionda, Giovanni Antonini, Antonio Petrucci, Roberto Bruni, Anna Rita Ciccaglione, Gloria Taliani, Marco Rivano Capparuccia, Eduardo Nobile-Orazio, Maurizio Inghilleri, Chiara Cambieri
Few studies have pointed to the possible role of infectious diseases in triggering Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). Given the association of Hepatitis E Virus (HEV) with Guillain Barrè syndrome, we conducted a case-control study to determine the possible association of HEV infection with CIDP, analyzing possible risk factors for acquiring HEV infection in both CIDP
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A nationwide survey of facial onset sensory and motor neuronopathy in Japan J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-11 Senri Ko, Ryo Yamasaki, Tasuku Okui, Wataru Shiraishi, Mitsuru Watanabe, Yu Hashimoto, Yuko Kobayakawa, Susumu Kusunoki, Jun-ichi Kira, Noriko Isobe
The epidemiology and etiology of facial onset sensory and motor neuronopathy (FOSMN), a rare syndrome that initiates with facial sensory disturbances followed by bulbar symptoms, remain unknown. To estimate the prevalence of FOSMN in Japan and establish the characteristics of this disease, we conducted a nationwide epidemiological survey. In the primary survey, we received answers from 604 facilities
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Evaluation of prognostic scores for status epilepticus in the neurology ICU: A retrospective study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-11 Jia Yi Shen, Seyed Ehsan Saffari, Linda Yong, Nigel Choon Kiat Tan, Yee-Leng Tan
Status epilepticus (SE) in the neurology intensive care unit (ICU) is associated with significant morbidity. We aimed to evaluate the utility of existing prognostic scores, namely the Status Epilepticus Severity Score (STESS), Epidemiology Based Mortality Score in Status Epilepticus (EMSE)-EACE and Encephalitis-Nonconvulsive Status Epilepticus-Diazepam Resistance-Image Abnormalities-Tracheal Intubation
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Long term quality of life follow-up and functional impairment study in patients with Hirayama disease J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-11 Adeel S. Zubair, Rafid Mustafa, Brian Crum
Hirayama Disease (HD) is a focal motor neuron disorder generally affecting young adults with a male predominance who experience weakness and atrophy in distal upper extremity muscles in an asymmetric or unilateral pattern. Progression is insidious though significant weakness occurs during a progressive phase of the disease over 2–5 years. The long-term outcome of HD is not as well-known and, thus,
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Diversity, equity, and inclusion (DEI) in medical education: DEI at the bedside J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-07 Tennyson S. Jellins, Tyler L. Borko, RayLee Otero-Bell, Kelly Arnett, Scott Saunders, Sharon N. Poisson, Karen D. Orjuela, Setareh Salehi Omran, William J. Jones, Michelle Leppert, Ashley Madera, Aaron Carlson, Daniel M. Pastula, Brian M. Sauer, Amanda L. Piquet, Nicole R. Gonzales
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Impact of dementia status on intravenous thrombolysis and endovascular treatment for acute ischemic stroke: Retrospective study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-07 Jonathan Naftali, Gal Tsur, Eitan Auriel, Rani Barnea, Michael Findler, Guy Raphaeli, Ran Brauner, Keshet Pardo, Alain Perlow, Galit Weinstein, Penina Weiss, Amir Glik, Ophir Keret
Individuals with dementia are underrepresented in interventional studies for acute ischemic stroke (AIS). This research gap creates a bias against their treatment in clinical practice. Our goal was to compare the safety and efficacy of intravenous-thrombolysis (t-PA) and endovascular treatment (EVT) in individuals with or without pre-AIS dementia. A retrospective study of AIS patients receiving t-PA
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Efficacy and safety of ketamine for pediatric and adolescent super-refractory status epilepticus and the effect of cerebral inflammatory conditions J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-06 Ichiro Kuki, Takeshi Inoue, Masataka Fukuoka, Megumi Nukui, Hideo Okuno, Kiyoko Amo, Yasunori Otsuka, Junichi Ishikawa, Hiroshi Rinka, Atushi Ujiro, Masao Togawa, Masashi Shiomi, Shin Okazaki
To investigate the short-term benefits and adverse effects of ketamine in the treatment of pediatric and adolescent super-refractory status epilepticus (SRSE), with a focus on the inflammatory etiology. This retrospective observational cohort study included a consecutive series of 18 pediatric to adolescent patients with SRSE admitted between 2008 and 2023 and treated with ketamine. Seizure frequency
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Pearls and pitfalls in letters of recommendation for neurology residency applications J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-05 Ryka R. Sehgal, Harini Sarva, Joseph E. Safdieh, Matthew S. Robbins
Letters of recommendation are a cornerstone of residency applications. Variability and bias in letters exists across specialties, neurology being no exception. Studies done in other specialty fields assessing nuanced language uncovered key attention points for improvement and mitigation of bias, lessons from which should be applied in the field of neurology. We review common pearls and pitfalls in
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Taste and smell function in Wilson's disease J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-05 Mandy K. Salmon, William G. Cohen, Fengling Hu, Adem Aydin, Ayse K. Coskun, Michael Schilsky, Richard L. Doty
Wilson's disease (WD) is a metabolic disorder associated with abnormal copper metabolism that results in hepatic, psychiatric, and neurologic symptoms. No investigation of taste function has been made in patients with WD, although olfactory dysfunction has been evaluated. Quantitative taste and smell test scores of 29 WD patients were compared to those of 790 healthy controls. Taste was measured using
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Venous sinus stenting for idiopathic intracranial hypertension: An updated Meta-analysis J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-05 Ahmed Y. Azzam, Ali Mortezaei, Mahmoud M. Morsy, Muhammed Amir Essibayi, Sherief Ghozy, Osman Elamin, Mohammed A. Azab, Adam Elswedy, David Altschul, Ramanathan Kadirvel, Waleed Brinjikji, David F. Kallmes
Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure and primarily affects obese women of reproductive age. Venous sinus stenting (VSS) is a surgical procedure used to treat IIH, but its safety and efficacy are still controversial. A systematic review and meta-analysis were conducted following PRISMA guidelines. Multiple databases were searched for studies evaluating
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A case of hereditary dementia: Is it Alzheimer's disease or not? J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-02 Chiara Giuseppina Bonomi, Matilde Bruno, Vito Luigi Colona, Mario Bengala, Alessandro Martorana
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Differing patterns of cortical grey matter pathology identified by multifractal analysis in UMN-predominant ALS patients with and without corticospinal tract hyperintensity J. Neurol. Sci. (IF 4.4) Pub Date : 2024-03-01 Venkateswaran Rajagopalan, Erik P. Pioro
The pathological hallmarks of amyotrophic lateral sclerosis (ALS) are degeneration of the primary motor cortex grey matter (GM) and corticospinal tract (CST) resulting in upper motor neuron (UMN) dysfunction. Conventional brain magnetic resonance imaging (MRI) shows abnormal CST hyperintensity in some UMN-predominant ALS patients (ALS-CST+) but not in others (ALS-CST–). In addition to the CST differences
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Retraction notice to Cerebrospinal fluid atypical lymphocytes in Japanese encephalitis” [JNS 160 (1998) 92–95] J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-29 Yoshihiro Sato, Naoki Hachiva, Haruko Kuno, Takeshi Asoh, Kotaro Oizumi
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The WFN Service page J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-29 Wolfgang Grisold, Steven L. Lewis
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Increased blood coagulation is associated with poor neurological outcome in aneurysmal subarachnoid hemorrhage J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-23 Essi Raatikainen, Heikki Kiiski, Anne Kuitunen, Eija Junttila, Heini Huhtala, Antti Kallonen, Marika Ala-Peijari, Jaakko Långsjö, Johanna Saukkonen, Timo Valo, Terhi Kauppila, Sanni Raerinne, Juhana Frösen, Annukka Vahtera
Patients with aneurysmal subarachnoid hemorrhage (aSAH) have demonstrated increased blood coagulation which is thought to contribute to delayed cerebral ischemia (DCI) and to a worse outcome. Therefore, we sought to determine whether this increased blood coagulation, detectable with rotational thromboelastometry (ROTEM), was associated with DCI and neurological outcome. We conducted a prospective observational
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Response to letter to the editor by Sterpetti et al J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-22 Jeroen Douwes, Mina Whyte, Annemarei Ranta
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Retraction notice to “Reply to Davie and Sharp: Different mechanisms of bone metabolism between patients with stroke and with spinal cord injury” [Journal of the Neurological Sciences 163 (1999) 100–101] J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-20 Yoshihiro Sato, Yukiko Fujimatsu, Munetsugu Kikuyama, Masahide Kaji, Kotaro Oizumi
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Retraction notice to “Histiocytic necrotizing lymphadenitis (Kikuchi's disease) with aseptic meningitis” [Journal of the Neurological Sciences 163 (1999) 187–191] J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-20 Yoshihiro Sato, Haruko Kuno, Kotaro Oizumi
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Retraction notice to “Rapid diagnosis of cryptococcal meningitis by microscopic examination of centrifuged cerebrospinal fluid sediment” [Journal of the Neurological Sciences 164 (1999) 72–75] J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-20 Yoshihiro Sato, Seishi Osabe, Haruko Kuno, Masahide Kaji, Kotaro Oizumi
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Clinical and biochemical profile of a patient with acute metonitazene intoxication J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-20 Samir Abu-Rumeileh, Philipp Burow, David Strube, Lorenzo Barba, Richard Ibe, Christopher M. Weise, Markus Otto
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High brain natriuretic peptide level is associated with severe stroke in patients taking oral anticoagulants: A sub-analysis of the PASTA registry study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-15 Satoshi Suda, Yasuyuki Iguchi, Yoshiki Yagita, Takao Kanzawa, Seiji Okubo, Shigeru Fujimoto, Yu Kono, Kazumi Kimura, on behalf of PASTA Investigators
Brain natriuretic peptides (BNP) are an important diagnostic and prognostic marker in patients with heart failure. However, the relationship between BNP levels and stroke severity in patients with atrial fibrillation (AF) remains unelucidated. In this study, we aimed to investigate the association between stroke severity at admission and BNP levels. In this prospective observational study, we used
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Identifying parkinsonism in mild cognitive impairment J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-15 Rishira Fernando, Alan J. Thomas, Calum A. Hamilton, Rory Durcan, Sally Barker, Joanna Ciafone, Nicola Barnett, Kirsty Olsen, Michael Firbank, Gemma Roberts, Jim Lloyd, George Petrides, Sean Colloby, Louise M. Allan, Ian G. McKeith, John T. O'Brien, John-Paul Taylor, Paul C. Donaghy
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Lower exposure to risk factors for stroke in green spaces in comparison with metropolitan areas. The importance of education and information to reduce the difference J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-14 Antonio V. Sterpetti, Raimondo Gabriele, Immacolata Iannone, Luca DiMarzo
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Spatial colocalization of imaging markers in iatrogenic cerebral amyloid angiopathy with the site of surgery: A metaanalysis J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-13 Ulf Jensen-Kondering
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Clinical characteristics of patients with Parkinson's disease with reduced 123I-metaiodobenzylguanidine uptake in the major salivary glands and heart J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-13 Junya Ebina, Sunao Mizumura, Harumi Morioka, Mari Shibukawa, Junpei Nagasawa, Masaru Yanagihashi, Takehisa Hirayama, Nobutomo Ishii, Yukio Kobayashi, Akira Inaba, Satoshi Orimo, Osamu Kano
Parkinson's disease (PD) shows cardiac sympathetic denervation (SD) in I-metaiodbezylguanidine (MIBG) scintigraphy. Recently, SD in the major salivary glands (MSG-SD) was introduced as a possible radiological feature of PD. To identify the clinical characteristics of patients with PD with reduced MSG and cardiac MIBG uptake (dual-SD) compared with those with reduced MSG or cardiac MIBG uptake only
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Real world data analysis of frontotemporal dementia: Implications for future clinical research J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-13 Stephen J. Peroutka
Frontotemporal dementia (FTD) is a progressive decline of cognitive abilities associated with other neuropsychiatric comorbidities. A real-world data (RWD) analysis of a large electronic healthcare records (EHR) database identified the comorbidities of FTD. Deidentified EHRs in the TriNetX Network database from >155,000,000 individuals in the United States established an FTD Cohort (ICD-10 Code G31
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Factors and brain imaging features associated with cognition in oldest-old patients with Alzheimer-type dementia J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-10 Haruo Hanyu, Yumi Koyama, Kazuki Umekida, Toshimitsu Momose, Sadayoshi Watanabe, Tomohiko Sato
The underlying pathophysiology of cognitive dysfunction in oldest-old patients with Alzheimer-type dementia (AD) has not been clarified to date. We aimed to determine the factors and brain imaging features associated with cognition in oldest-old patients with AD. We enrolled 456 consecutive outpatients with probable AD (145 men and 311 women, age range: 51–95 years). Demographic factors, such as education
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Natalizumab extended interval dosing: what about wearing-off effect? J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-10 Catarina Bernardes, Catarina Fernandes, Carolina Cunha, Carla Nunes, Carmo Macário, Lívia Sousa, Sónia Batista, Inês Correia
Up to two thirds of patients with multiple sclerosis (MS) under natalizumab report a resurgence of symptoms at the end of the natalizumab cycle (wearing-off (WO) effect). At the outbreak of COVID-19, in line with the international recommendations for MS management, our centre switched all clinically stable patients on natalizumab therapy for more than one year from standard interval dosing (SID) to
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Editorial on an autoencoder algorithm for the prediction of stroke patients with left ventricular thrombus (LVT) J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-08 Muhammad Khaliq, Ibraheem Shaikh, Salil Soman
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Impaired sleep is associated with tau deposition on 18F-flortaucipir PET and accelerated cognitive decline, accounting for medications that affect sleep J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-08 Ryan T. Kim, Liangdong Zhou, Yi Li, Ana C. Krieger, Anna S. Nordvig, Tracy Butler, Mony J. de Leon, Gloria C. Chiang, the Alzheimer's Disease Neuroimaging Initiative
Impaired sleep is commonly associated with Alzheimer's disease (AD), although the underlying mechanisms remain unclear. Furthermore, the moderating effects of sleep-affecting medications, which have been linked to AD pathology, are incompletely characterized. Using data from the Alzheimer's Disease Neuroimaging Initiative, we investigated whether a medical history of impaired sleep, informant-reported
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Disease-modifying therapy use and health resource utilisation associated with multiple sclerosis over time: A retrospective cohort study from Alberta, Canada J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-07 Erin F. Balcom, Penelope Smyth, Mahesh Kate, Khanh Vu, Karen J.B. Martins, Sylvia Aponte-Hao, Huong Luu, Lawrence Richer, Tyler Williamson, Scott W. Klarenbach, Jennifer A. McCombe
Estimating multiple sclerosis (MS) prevalence and incidence, and assessing the utilisation of disease-modifying therapies (DMTs) and healthcare resources over time is critical to understanding the evolution of disease burden and impacts of therapies upon the healthcare system. A retrospective population-based study was used to determine MS prevalence and incidence (2003–2019), and describe utilisation
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Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-07 Federico Rodriguez-Porcel, Harini Sarva, Juho Joutsa, Cristian Falup-Pecurariu, Aparna Wagle Shukla, Raja Mehanna, Katarzyna Śmiłowska, Giuseppe Lanza, Saša R. Filipović, Ali Shalash, Margaret Ferris, Joseph Jankovic, Alberto J. Espay, Sanjay Pandey, on behalf of the Post-Stroke Movement Disorders Study Group from the Movement Disorders Society
Post-stroke movement disorders (PSMD) encompass a wide array of presentations, which vary in mode of onset, phenomenology, response to treatment, and natural history. There are no evidence-based guidelines on the diagnosis and treatment of PSMD. To survey current opinions and practices on the diagnosis and treatment of PSMD. A survey was developed by the PSMD Study Group, commissioned by the International
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Efficacy and safety outcomes of Tenecteplase versus Alteplase for thrombolysis of acute ischemic stroke: A meta-analysis of 9 randomized controlled trials J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-03 Yue Wang, Xiuying Cai, Qi Fang, Juehua Zhu
In recent years, Tenecteplase (TNK), a genetically modified variant of alteplase, has been verified as a potential substitute for alteplase in the reperfusion therapy of acute ischemic stroke (AIS). Given the emergence of new randomized controlled trials (RCTs) of this subject, a meta-analysis was conducted to evaluate the present comparative evidence regarding the efficacy and safety outcomes of TNK
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The future of brain health advocacy: Recommendations of the 2023 World Congress of Neurology advocacy panel J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-02 Mohammad Wasay, Wolfgang Grisold, Tissa Wijeratne, Walter Struhal, Safa Younis, On behalf of the World Federation of Neurology
Abstract not available
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Proximal sensory neuropathy and cerebellar ataxia as presenting symptoms of NOTCH2NLC-related neuronal intranuclear inclusion disease J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-02 Kai Funakawa, Masanori Kurihara, Kensuke Takahashi, Mana Higashihara, Manato Hara, Akihiko Mitsutake, Hiroyuki Ishiura, Aya Midori Tokumaru, Masahiro Sonoo, Shigeo Murayama, Yuko Saito, Atsushi Iwata
Abstract not available
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Serum teriflunomide concentrations in routine multiple sclerosis therapy: A cross-sectional pilot study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-01 Zuzana Krska Kusnirikova, Ivana Kacirova, Veronika Pesakova, Pavel Hradilek, Hana Brozmanova, Milan Grundmann
Teriflunomide is administered orally to treat relapsing-remitting multiple sclerosis. In this prospective pilot study, the free and total serum concentrations of teriflunomide obtained during routine health care were measured and their relationship with disease activity was evaluated. Eighty-nine patients were included in this study. Blood samples were collected from April 2021 to February 2022, and
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MiR-182 in Glioma: An insufficiently explored and controversial research area J. Neurol. Sci. (IF 4.4) Pub Date : 2024-02-01 Lin-Lin Chen, Xiao-Yang Zhao
Abstract not available
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Characterization of neurological morbidity associated with thyroid antibodies: Hashimoto's encephalopathy and beyond J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-30 Mark P. Figgie Jr, Hannah Kelly, Natalie Pyatka, Clara Chu, Hesham Abboud
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Qualitative interviews to support development of a patient-reported companion measure to the Glucocorticoid Toxicity Index J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-30 Timothy A. Howell, Louis S. Matza, John H. Stone, Deborah Gelinas, Martha N. Stone, Vijayaraghava T.S. Rao, Glenn A. Phillips
Introduction Glucocorticoids (GCs) are associated with multiple toxicities that have substantial impact on patients. We conducted qualitative interviews with patients to identify the toxicities that are most relevant from their perspective, with the goal of creating a patient-reported companion measure to the Glucocorticoid Toxicity Index (GTI), a clinician-facing instrument. Methods Thirty-one patients
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Predictors of relapsing disease course following index event in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-30 Negar Molazadeh, Philippe A. Bilodeau, Rebecca Salky, Gauruv Bose, Itay Lotan, Gabriela Romanow, Monique R. Anderson, Marcelo Matiello, Tanuja Chitnis, Michael Levy
Background Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune disease that can present as a monophasic or relapsing disease course. Here, we investigate the predictors of developing relapsing disease with a focus on the index event. Methods MOGAD patients followed at Massachusetts General Hospital and Brigham and Women's Hospital were included. Data on demographic
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Optimization of oral entacapone administration in patients undergoing levodopa–carbidopa intestinal gel treatment J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-24 Noriyuki Miyaue, Yuko Ito, Yuki Yamanishi, Satoshi Tada, Rina Ando, Hayato Yabe, Masahiro Nagai
Background Levodopa–carbidopa intestinal gel (LCIG) treatment markedly reduces motor fluctuations in patients with Parkinson's disease; however, some patients undergoing LCIG treatment may demonstrate clinical deterioration in the afternoon. Entacapone, a catechol-O-methyltransferase inhibitor, may be a promising adjunctive option for LCIG-treated patients; however, the optimal timing of oral entacapone
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Dual target deep brain stimulation for complex essential and dystonic tremor – A 5-year follow up J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-26 Hilary Shepherd, Rosie Heartshorne, Jibril Osman-Farah, Antonella Macerollo
Background Essential tremor (ET) is characterized by action tremor of the upper limbs, head tremor and voice tremor. Dystonic tremor (DT) is produced by muscle contractions in a body affected by dystonia. Deep brain stimulation (DBS) of ventral intermediate nucleus of the thalamus (VIM) is the most well-known advanced treatment for medication-refractory tremor. However, decline in efficacy overtime
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Prevalence of Fabry disease and GLA variants in young patients with acute stroke: The challenge to widen the screening. The Fabry-stroke Italian registry J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-24 Ilaria Romani, Cristina Sarti, Patrizia Nencini, Giovanni Pracucci, Marialuisa Zedde, Vittoria Cianci, Antonia Nucera, Jessica Moller, Daniele Orsucci, Danilo Toni, Pasquale Palumbo, Carmela Casella, Vincenza Pinto, Leonardo Barbarini, Rita Bella, Umberto Scoditti, Michele Ragno, Domenico Maria Mezzapesa, Rossana Tassi, Gino Volpi, Domenico Inzitari
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Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-23 Stephen A. Goutman, Jonathan Boss, Dae Gyu Jang, Caroline Piecuch, Hasan Farid, Madeleine Batra, Bhramar Mukherjee, Eva L. Feldman, Stuart A. Batterman
Introduction Environmental exposures strongly influence ALS risk and identification is needed to reduce ALS burden. Participation in hobbies and exercise may alter ALS risk and phenotype, warranting an assessment to understand their contribution to the ALS exposome. Methods Participants with ALS and healthy controls were recruited from University of Michigan and self-completed a survey to ascertain
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Fast but not furious: Rapid ocrelizumab infusion as a strategy to optimize multiple sclerosis patients' management J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-20 Chiara Zanetta, Patricia Faustino, Simone Guerrieri, Agostino Nozzolillo, Angela Genchi, Chiara Bucca, Maria A. Rocca, Lucia Moiola, Massimo Filippi
Objectives Multiple sclerosis clinicians are continuously challenged to be innovative in delivering therapies and there is ongoing pressure to maximize day-hospital vacancies. We describe our single-center experience with ocrelizumab (OCR) rapid infusion (OCR-RI) in patients with MS (pwMS). Methods For pwMS with prior exposure to OCR standard infusion (OCR-SI) for at least one year/two cycles, infusion
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The influence of limbic-predominant age-related TDP-43 encephalopathy on argyrophilic grain disease: A voxel-based morphometry analysis of pathologically confirmed cases J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-19 Shohei Inui, Daita Kaneda, Keita Sakurai, Satoru Morimoto, Yuto Uchida, Osamu Abe, Yoshio Hashizume
Background The influence of limbic-predominant age-related TAR DNA-binding protein of 43 kDa encephalopathy neuropathological change (LATE-NC) on structural alterations in argyrophilic grain disease (AGD) have not been documented. This study aimed to investigate the morphological impact of LATE-NC on AGD through voxel-based morphometry (VBM) technique. Materials and methods Fifteen individuals with
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Disrupted social perception in frontotemporal dementia and Alzheimer's disease – Associated cognitive processes and clinical implications J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-24 Nikki-Anne Wilson, Rebekah Ahmed, Olivier Piguet, Muireann Irish
Background Social perception refers to the ability to adapt and update one's behaviour in accordance with the current context and provides the foundation for many complex social and emotional interactions. Alterations in social cognition are a hallmark of the behavioural variant of frontotemporal dementia (bvFTD), yet the capacity for social perception in this syndrome remains unclear. Methods We examined
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Asymptomatic or agnostic? Precision medicine of hemorrhagic transformation after endovascular therapy J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-24 David S. Liebeskind
Abstract not available
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Increasing incidence of Parkinson's disease in patients with epilepsy: A Nationwide cohort study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-24 Yun Su Hwang, Min Gu Kang, Sang Woo Yeom, Cho Yun Jeong, Byoung-Soo Shin, Jihoon Koh, Jong Seung Kim, Hyun Goo Kang
Background Although epilepsy is an uncommon comorbidity of Parkinson's disease (PD), the exact incidence of PD among the patients with epilepsy is not clarified yet. Objectives We aimed to estimate the incidence of PD in patients with epilepsy and explore the association between epilepsy and PD. Methods Epilepsy patients enrolled in the National Health Insurance Service Health Screening Cohort (NHIS-HealS)
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Factors influencing the development of infantile traumatic brain injury with a biphasic clinical course and late reduced diffusion J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-24 Madoka Yasukohchi, Taku Omata, Kenta Ochiai, Kentaro Sano, Yuka Murofushi, Sho Kimura, Nanako Takase, Takafumi Honda, Kumi Yasukawa, Jun-ichi Takanashi
Background Infantile traumatic brain injury (TBI) with a biphasic clinical course and late reduced diffusion (TBIRD) has been reported as a type of TBI. However, it remains uncertain which pediatric patients with TBI develop TBIRD. Methods Patients with TBI who were admitted to our hospital and underwent magnetic resonance imaging (MRI) between December 2006 and October 2022 were included in this study
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Proton pump inhibitors and amyotrophic lateral sclerosis: A case-control study J. Neurol. Sci. (IF 4.4) Pub Date : 2024-01-20 Maria Eduarda Cardoso Tortorella, Inês Alves, Marta Gromicho, Miguel Oliveira Santos, Mamede de Carvalho
Abstract not available