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The Critical Role of Intracellular Bacterial Communities in Uncomplicated Recurrent Urinary Cystitis: A Comprehensive Review of Detection Methods and Diagnostic Potential. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Yeonjoo Kwak, Hyeong Gon Kim, Jaekwon Seok, Sehwan Kim, Eun-Mee Kim, Aram Kim
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide and are particularly prevalent in women. Recurrent UTIs significantly diminish quality of life due to their symptoms and frequent relapses. Patients often experience immediate relapse following slightly strenuous activities or intense psychological stress. In this review, we explore why infections persist despite
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Pudendal Nerve Neurolysis in Patients Afflicted With Pudendal Nerve Entrapment: A Systematic Review of Surgical Techniques and Their Efficacy. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Carlo Giulioni, Giacomo Maria Pirola, Martina Maggi, Lucia Pitoni, Demetra Fuligni, Mattia Beltrami, Vanessa Palantrani, Virgilio De Stefano, Valentina Maurizi, Daniele Castellani, Andrea Benedetto Galosi
To assess the effectiveness and safety of various techniques of pudendal nerve neurolysis (PNN) in patients with pudendal nerve entrapment (PNE). A comprehensive literature search was conducted on May 20th, 2023, using Scopus, PubMed, and Embase databases. Only studies in English involving adults were accepted, while meeting abstracts and preclinical studies were excluded. A total of 34 papers were
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Impact of Exercise Training on Survival Rate and Neural Cell Death in Sepsis Through the Maintenance of Redox Equilibrium. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Taewan Kim, Youngyun Jin, Jinkyung Cho, Donghyun Kim
Sepsis-related deaths occur during both the early proinflammatory and the late immunosuppressive phases of the condition. The balance of pro- and anti-inflammatory responses is influenced by damaged cells that die via either proinflammatory necroptosis or anti-inflammatory apoptosis. Both forms of cell death may be mediated by reactive oxygen species (ROS) generated during the proinflammatory response
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Prediction of Prostate Cancer Risk Stratification Based on A Nonlinear Transformation Stacking Learning Strategy. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Xinyu Cao, Yin Fang, Chunguang Yang, Zhenghao Liu, Guoping Xu, Yan Jiang, Peiyan Wu, Wenbo Song, Hanshuo Xing, Xinglong Wu
Prostate cancer (PCa) is an epithelial malignancy that originates in the prostate gland and is generally categorized into low, intermediate, and high-risk groups. The primary diagnostic indicator for PCa is the measurement of serum prostate-specific antigen (PSA) values. However, reliance on PSA levels can result in false positives, leading to unnecessary biopsies and an increased risk of invasive
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Benign Prostatic Hyperplasia and the Risk of Falls in Older Men: Insights From a Population-Based Study on Geriatric Morbid Conditions. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Sung Jin Kim, Donghyun Lee, Sung Gon Park, Sahyun Pak, Young Goo Lee, Sung Tae Cho
The purpose of this study was to explore the association between benign prostatic hyperplasia (BPH) and the incidence of falls from the perspective of geriatric morbid conditions.
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Efficacy and Safety of Low-Dose Intravesical OnabotulinumtoxinA Injections in Female Patients With Detrusor Overactivity With Detrusor Underactivity. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Hyun Seok Na, Chung Lyul Lee, Jae Sung Lim, Ki Hak Song, Ju Hyun Shin, Jong Mok Park, Ji Yong Lee
We assessed the effectiveness and safety of using intravesical onabotulinumtoxinA (onabotA; BOTOX) injection with a low dose (75 units) for treating urinary storage symptoms in patients with detrusor overactivity with detrusor underactivity (DODU) compared to using the standard 100 units of onabotA in patients with overactive bladder (OAB).
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Surgical Outcomes and Predictive Factors in Patients With Detrusor Underactivity Undergoing Bladder Outlet Obstruction Surgery. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Ming-Syun Chuang, Yin-Chien Ou, Yu-Sheng Cheng, Kuan-Yu Wu, Chang-Te Wang, Yuan-Chi Huang, Yao-Lin Kao
This study was conducted to evaluate the efficacy of bladder outlet surgery in patients with detrusor underactivity (DU) and to identify factors associated with successful outcomes.
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Water Vapor Therapy and Zonal Anatomy of the Prostate. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-03-31 Jang Hwan Kim, Hee Youn Kim, Seung-Ju Lee, Dong Sup Lee
Water vapor therapy using Rezūm has been recently introduced as a minimally invasive surgery for benign prostatic hyperplasia and is being increasingly performed. However, there is a lack of real-time images showing this practice and how convective water vapor acts in the prostate gland. In real-time ultrasonography, convective water vapor rapidly spreads throughout the ipsilateral transitional zone
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The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go? Int. Neurourol. J. (IF 2.3) Pub Date : 2024-02-29 Gabriel Faria-Costa, João Oliveira, Inês Vilas-Boas, Inês Campelo, Elisa Azeredo Silva, Carmen Brás-Silva, Susana Maria Silva, Tiago Antunes-Lopes, Ana Charrua
Metabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles exacerbate abnormal carbohydrate metabolism and sustain an inflammatory state, with serious implications for both the heart and bladder. Ketone bodies serve as an alternative energy
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Pathophysiology of Overactive Bladder and Pharmacologic Treatments Including β3-Adrenoceptor Agonists -Basic Research Perspectives. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-02-29 Joonbeom Kwon, Duk Yoon Kim, Kang Jun Cho, Mamoru Hashimoto, Kanako Matsuoka, Tadanobu Kamijo, Zhou Wang, Sergei Karnup, Anne M Robertson, Pradeep Tyagi, Naoki Yoshimura
Overactive bladder (OAB) is a symptom-based syndrome defined by urinary urgency, frequency, and nocturia with or without urge incontinence. The causative pathology is diverse; including bladder outlet obstruction (BOO), bladder ischemia, aging, metabolic syndrome, psychological stress, affective disorder, urinary microbiome, localized and systemic inflammatory responses, etc. Several hypotheses have
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Detrusor Overactivity After Partial Bladder Outlet Obstruction Is Associated With High Urinary Adenosine Triphosphate Levels in Female Wistar Rats. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-02-29 Luís Vale, Francisco Cruz, Ana Charrua
Bladder outlet obstruction (BOO) commonly causes detrusor overactivity (DO). In this study, a post hoc analysis of previous obtained data, we investigate if DO occurring in initial phases of BOO is associated with changes in urinary adenosine triphosphate (ATP) levels.
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Quantification of Aging-Related Decreases in Sensory Innervation of the Bladder Trigone in Rats. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-02-29 Mathijs M de Rijk, Saša Peter, Amanda Wolf-Johnston, John Heesakkers, Gommert A van Koeveringe, Lori A Birder
The prevalence of lower urinary tract symptoms (LUTS), characterized by problems regarding storage and/or voiding of urine, is known to significantly increase with age. Effective communication between the lower urinary tract and the central nervous system (CNS) is essential for the optimal function of this system, and heavily relies on the efficient interaction between the bladder urothelium and the
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Adreno-Muscarinic Synergy of Contractile Responses From Human Hyperplastic Prostate. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-02-29 Ben T Blake-James, Basu Chakrabarty, Christopher H Fry
Adreno-muscarinic synergy, a supra-additional contractile response to simultaneous application of α-adrenoreceptor and muscarinic receptor agonists, is a feature of several lower urinary tract regions that have dual sympathetic and parasympathetic innervation. We tested the hypothesis that synergy is also a feature of prostate tissue obtained from men with benign prostatic enlargement.
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Application of the Sleep C.A.L.M. Tool for Assessing Nocturia in a Large Nationally Representative Cohort. Int. Neurourol. J. (IF 2.3) Pub Date : 2024-02-29 Joseph U Boroda, Benjamin De Leon, Lakshay Khosla, Muchi D Chobufo, Syed N Rahman, Jason M Lazar, Jeffrey P Weiss, Thomas F Monaghan
Nocturia significantly impacts patients' quality of life but remains insufficiently evaluated and treated. The "Sleep C.A.L.M." system categorizes the factors thought to collectively reflect most underlying causes of nocturia (Sleep disorders, Comorbidities, Actions [i.e., modifiable patient behaviors such as excess fluid intake], Lower urinary tract dysfunction, and Medications). The purpose of this
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The Current State of Artificial Intelligence Application in Urology. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Eui-Sun Kim, Sung-Jong Eun, Seunghyun Youn
Artificial intelligence (AI) is being used in many areas of healthcare, including disease diagnosis and personalized treatment and rehabilitation management. Medical AI research and development has primarily focused on diagnosis, prediction, treatment, and management as an aid to patient care. AI is being utilized primarily in the areas of personal healthcare and diagnostic imaging. In the field of
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Differential Gene Expression in the Penile Cavernosum of Streptozotocin-Induced Diabetic Rats. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Jae Heon Kim, Hee Jo Yang, Suyeon Park, Hong Jun Lee, Yun Seob Song
Men with diabetes mellitus (DM) often present with severe erectile dysfunction (ED). This ED is less responsive to current pharmacological therapies. If we know the upregulated or downregulated genes of diabetic ED, we can inhibit or enhance the expression of such genes through RNA or gene overexpression.
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Adenosine A2A Receptor Agonist, Polydeoxyribonucleotide Treatment Improves Locomotor Function and Thermal Hyperalgesia Following Neuropathic Pain in Rats. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Ye Chan Joo, Jun Young Chung, Soon Oh Kwon, Jin Hee Han
Lithotomy position has been widely used in the various urologic surgery. Occasionally sensory and motor problems of the lower extremities are occurred due to the lithotomy position and these deficits may be related with sciatic nerve injury (SNI). Inflammatory process is a factor to induce functional impairment after SNI. Therefore, we evaluated the role of adenosine A2A receptor agonists, polydeoxyribonucleotide
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The Risk of Stress Urinary Incontinence After Hysterectomy for Uterine Fibroids. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Jin-Sung Yuk, In-Chang Cho, Jun Ho Lee
We evaluated the relationship between previous hysterectomy for uterine fibroids and subsequent stress urinary incontinence (SUI).
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Intravesical Electrical Stimulation Improves Abnormal Prefrontal Brain Activity in Patients With Underactive Bladder: A Possible Central Mechanism. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Han Deng, Limin Liao, Juan Wu, Li Wan
The aim of this study was to explore the mechanisms of central brain action in patients with neurogenic underactive bladder (UAB) treated with intravesical electrical stimulation (IVES).
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Decreased Angiopoietin Expression in Underactive Bladder Induced by Long-term Bladder Outlet Obstruction. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Jae Heon Kim, Hee Jo Yang, Hong Jun Lee, Yun Seob Song
Ischemia of the bladder can occur if neovascular formation cannot keep pace with hypoxia induced by chronic bladder outlet obstruction (BOO). The aim of this study was to examine changes in angiogenesis growth factor expression generated by chronic BOO in a rat model of underactive bladder.
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Artificial Intelligence-Based Patient Monitoring System for Medical Support. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-12-31 Eui-Sun Kim, Sung-Jong Eun, Khae-Hawn Kim
In this paper, we present the development of a monitoring system designed to aid in the management and prevention of conditions related to urination. The system features an artificial intelligence (AI)-based recognition technology that automatically records a user's urination activity. Additionally, we developed a technology that analyzes movements to prevent neurogenic bladder.
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Designing Digital Therapeutic Content Using Chronic Disease Data: A Focus on Improving Urinary Dysfunction. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-11-30 Jungjo Na, Su Jin Kim, Yangmi Lim
In recent years, advancements in information and communication technologies, including artificial intelligence, big data, virtual reality, and augmented reality, have driven substantial growth in the field of digital medical diagnosis and treatment, thereby enhancing quality of life. Beginning in the mid-2010s with the advent of digital healthcare applications, and further accelerated by the impact
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General Overview of Artificial Intelligence for Interstitial Cystitis in Urology. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-11-30 Yongwon Cho, Jong Mok Park, Seunghyun Youn
Our understanding of interstitial cystitis/bladder pain syndrome (IC/BPS) has evolved over time. The diagnosis of IC/BPS is primarily based on symptoms such as urgency, frequency, and bladder or pelvic pain. While the exact causes of IC/BPS remain unclear, it is thought to involve several factors, including abnormalities in the bladder's urothelium, mast cell degranulation within the bladder, inflammation
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Emerging Trends in Artificial Intelligence-Based Urological Imaging Technologies and Practical Applications. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-11-30 Hyun Suh Kim, Eun Joung Kim, JungYoon Kim
The integration of artificial intelligence (AI) into medical imaging has notably expanded its significance within urology. AI applications offer a broad spectrum of utilities in this domain, ranging from precise diagnosis achieved through image segmentation and anomaly detection to improved procedural assistance in biopsies and surgical interventions. Although challenges persist concerning data security
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Hybrid Bladder Phantom to Validate Next-Generation Optical Wearables for Neurogenic Bladder Volume Monitoring. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-11-30 Kelsey J Tu, Jesse H Lam, Byeong-Il Kang, Aram Kim, Sehwan Kim
The development of optics-based wearables for bladder volume monitoring has emerged as a significant topic in recent years. Given the innovative nature of this technology, there is currently no bladder phantom available to effectively validate these devices against more established gold standards, such as ultrasound. In this study, we showcase and demonstrate the performance of our hybrid bladder phantom
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Insights Into Korean Public Perspectives on Urology: Online News Data Analytics Through Latent Dirichlet Allocation Topic Modeling. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-11-30 Young Wook Oh, JungYoon Kim
The objective of the study was to explore how urology-related news, one of the medical specialties profoundly linked to human health and life, is communicated to the public through media outlets that serves as primary sources of medical information for the public.
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Improved Detection of Urolithiasis Using High-Resolution Computed Tomography Images by a Vision Transformer Model. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-11-30 Hyoung Sun Choi, Jae Seoung Kim, Taeg Keun Whangbo, Sung Jong Eun
Urinary stones cause lateral abdominal pain and are a prevalent condition among younger age groups. The diagnosis typically involves assessing symptoms, conducting physical examinations, performing urine tests, and utilizing radiological imaging. Artificial intelligence models have demonstrated remarkable capabilities in detecting stones. However, due to insufficient datasets, the performance of these
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Stress, Anxiety, and Urine: The Evolutionary Tactics to Survival and How We Became Anxious in Public Restrooms. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Jin Wook Kim
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Differentially Expressed mRNA in Streptozotocin-Induced Diabetic Bladder Using RNA Sequencing Analysis. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Jae Heon Kim, Hee Jo Yang, Hong J Lee, Yun Seob Song
To detect elements governing the pathogenesis of diabetic cystopathy (DC), mRNA sequencing was carried out for bladder tissues from normal rats and those with induced diabetes mellitus (DM). This research therefore offers possible underlying molecular pathways for the advancement of DC in relation to differential mRNA expression, together with visceral functional and architectural alterations noted
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Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Rosa L Coolen, Dennis Frings, Els van Asselt, Jeroen R Scheepe, Bertil F M Blok
The global prevalence of overactive bladder (OAB) is estimated at 11.8%. Despite existing treatment options such as sacral neuromodulation, a substantial number of patients remain untreated. One potential alternative is noninvasive transcutaneous electrical stimulation. This form of stimulation does not necessitate the implantation of an electrode, thereby eliminating the need for highly skilled surgeons
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Is the Brainstem Activation Different Between Healthy Young Male and Female Volunteers at Initiation of Voiding? A High Definition 7-Tesla Magnetic Resonance Imaging Study. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Bradley Schott, Darshil Choksi, Khue Tran, Christof Karmonik, Betsy Salazar, Timothy Boone, Rose Khavari
Assessing brainstem function in humans through typical neuroimaging modalities has been challenging. Our objective was to evaluate brain and brainstem activation patterns during initiation of voiding in healthy males and females utilizing a 7 Tesla magnetic resonance imaging (MRI) scanner and a noninvasive brain-bladder functional MRI (fMRI) protocol.
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Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Chih-Chieh Lin, Hann-Chorng Kuo, Jian-Ri Li, Yao-Chi Chuang
We evaluated the therapeutic effects on overactive bladder (OAB) symptoms and sexual function of behavioral therapy with or without mirabegron in sexually active male patients with OAB. Mirabegron, a selective β3 adrenoceptor agonist for the treatment of OAB, has been shown to induce corpus cavernosum relaxation.
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Changes in Autonomic Nervous System Activity in Children With Spina Bifida: A Case-Control Study. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Byeong Seon Kim, Israel Franco, Yong Seung Lee, Sang Won Han, Sang Woon Kim
We compared heart rate variability parameters between patients with spina bifida and a control group during urodynamic studies, with the goal of evaluating the autonomic nervous system dysfunction present in spina bifida.
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Risk Factors of Salvage Procedure for Refractory Morcellation During Holmium Laser Enucleation of the Prostate. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Hyun Sik Yoon, Dae Hyuk Chung, Sung Yong Cho, Min Chul Cho, Jae-Seung Paick, Seung-June Oh
We aimed to identify the risk factors for salvage procedure (SP) required for refractory adenomatous tissue resistant to morcellation during holmium laser enucleation of the prostate (HoLEP).
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Kidney Transplantation and Clinical Outcomes in Patients With Multiple Myeloma: Evidence From the United States Nationwide Inpatient Sample. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Bo Yang, Lijuan Zhang, Xuechun Lu
Patients with multiple myeloma (MM) are prone to developing persistent renal insufficiency. Novel therapeutic medications have improved long-term survival, making kidney transplantation (KT) a viable treatment option for MM survivors with end-stage renal disease. This study aimed to investigate the clinical outcomes in patients with MM who have received KT.
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The Effect of Running Water Sound Listened to Patients During Urodynamics on Anxiety and Urodynamic Parameters. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-09-30 Yeliz Çulha, Ezgi Seyhan Ak, Mehmet Gökhan Çulha
This study was conducted to determine the effect of listening to the sound of running water during urodynamics on the patient's anxiety and parameters in the pressure-flow study.
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Outcomes and Complication Rates of Cuff Downsizing in the Treatment of Worsening or Persistent Incontinence After Artificial Urinary Sphincter Implantation. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Sylvia Weis, Tim A Ludwig, Omar Bahassan, Philipp Gild, Malte W Vetterlein, Margit Fisch, Roland Dahlem, Valentin Maurer
This study investigated the functional outcomes and complication rates of cuff downsizing for the treatment of recurrent or persistent stress urinary incontinence (SUI) in men after the implantation of an artificial urinary sphincter (AUS).
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Effect of Diabetes Mellitus on Symptomatic Improvement After Surgery for Benign Prostatic Hyperplasia in Patients With Lower Urinary Tract Symptom and its Relations With Prostatic Urethral Angulation. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Jung Ki Jo, Hwanik Kim, Woo Jin Bang, Cheol Young Oh, Jin Seon Cho, Myungsun Shim
To compare improvement of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia in diabetic versus nondiabetic patients after transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HoLEP).
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Role of Pelvic Ischemia in Human Lower Urinary Tract Symptoms and Sexual Function Among Patients With Common Iliac Artery Obstruction Undergoing Revascularization Surgery. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Efstathios Papaefstathiou, Sotirios Gatsos, Konstantinos Tigkiropoulos, Ioannis Apostolidis, Periklis Koukourikis, Ioannis Lazaridis, Apostolos Apostolidis
In this case-control study, we explored the relationships among pelvic ischemia, lower urinary tract symptoms (LUTS), and sexual function in patients with common iliac artery steno-occlusive disease, along with the potential therapeutic role of revascularization.
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Should Psychiatric Symptoms Be Evaluated in Elderly Males With Lower Urinary Tract Symptoms? Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Dong Yun Lee,Sung Chul Kam
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High Prevalence of Dysplastic Development of Sacral Vertebral Arches in Pediatric Enuresis. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Hideo Ozawa, Takakuki Shibano, Isao Tanaka, Toshitaka Taniguchi, Michael B Chancellor, Naoki Yoshimura
This is the first report to compare 3-dimensional computed tomography (3D-CT) images between pediatric patients with enuresis and children without lower urinary tract symptoms who underwent pelvic CT for other reasons.
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A Randomized, Double-Blind, Placebo-Controlled, Bridging Study to Evaluate the Efficacy and Safety of Vibegron in Treating Korean Patients With Overactive Bladder. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Jung Hyun Shin, Seong Jin Jeong, Sun-Ouck Kim, Cheol Young Oh, Kyung Jin Chung, Dong Gil Shin, Tae Hyo Kim, Joonbeom Kwon, Ju-Hyun Shin, Woong Jin Bae, Kyu-Sung Lee, Myung-Soo Choo
Vibegron, a novel, potent β3 agonist, has been approved for clinical use in overactive bladder (OAB) treatment in Japan and the Unites States. We performed a bridging study to investigate the efficacy and safety of a daily 50-mg vibegron (code name JLP-2002) dose in Korean patients with OAB.
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Comprehensive Analysis of Individual Anatomical Structures for Micturition Symptoms and Maximum Flow Rate in Men With Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Dae Ho Kim, Kwang Suk Lee, Kyo Chul Koo, Byung Ha Chung, Jeong Woo Yoo
Individual anatomical structural variations, including intravesical prostatic protrusion (IPP), prostatic urethral angle (PUA), prostatic urethral length, or prostatic apex shape, were correlated with micturition symptoms. We aimed to investigate the effects of these variables on micturition symptoms in men with benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS).
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Artificial Intelligence-Based Speech Analysis System for Medical Support. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Eui-Sun Kim, Dong Jin Shin, Sung Tae Cho, Kyung Jin Chung
Prior research has indicated that stroke can influence the symptoms and presentation of neurogenic bladder, with various patterns emerging, including abnormal facial and linguistic characteristics. Language patterns, in particular, can be easily recognized. In this paper, we propose a platform that accurately analyzes the voices of stroke patients with neurogenic bladder, enabling early detection and
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Competitive Inoculation as an Effective Prophylaxis Against Recurrent Urinary Tract Infections: A Systematic Review. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Quentin Mak, Julian Greig, Kamran Ahmed, Shamim Khan, Prokar Dasgupta, Sachin Malde, Nicholas Raison
Urinary tract infection (UTI) is a common condition defined as the presence of bacteria within the urine above a certain threshold (usually >100,000 m/L). The lifetime risk in women is estimated to be 50%, of whom 25% will develop recurrence within 6 months. Unfortunately, the use of antibiotics to treat and manage recurrent UTI (rUTI) is a growing problem, due to the burden of growing antibiotic resistance
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Time-Dependent Changes in the Bladder Muscle Metabolome After Traumatic Spinal Cord Injury in Rats Using Metabolomics. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Ying-Hao Liu, Qian Gong, Yi-Kai Wang, Wei-Bing Shuang
The main treatment options of neurogenic bladder remains catheterization and long-term oral medications. Metabolic interventions have shown good therapeutic results in many diseases. To date, no studies have characterized the metabolites of the detrusor muscle during neurogenic bladder. Using metabolomics, new muscle metabolomic signatures were identified to reveal the temporal metabolic profile of
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All Clinical Practice Should Embrace Research. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-06-30 Khae Hawn Kim
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A Novel Incisionless Disposable Vaginal Device for Female Stress Urinary Incontinence: Efficacy and Quality of Life. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-05-31 Chung Lyul Lee,Jong Mok Park,Ji Yong Lee,Seung Woo Yang,Hyun Seok Na,Jaegeun Lee,Sunkyung Jung,Ju Hyun Shin
PURPOSE This clinical study sought to evaluate the possible clinical effectiveness and practicality of URINO, an innovative, incisionless, and disposable intravaginal device, designed for patients suffering from stress urinary incontinence. METHODS A prospective, multicenter, single-arm clinical trial was carried out, involving women diagnosed with stress urinary incontinence who used a self-inserted
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Advancing Patient Care: Innovative Use of Near-Infrared Spectroscopy for Monitoring Urine Volume in Neurogenic Bladder. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-05-31 Byeong-Il Kang,Aram Kim,Sehwan Kim
PURPOSE Current guidelines recommend clean intermittent catheterization (CIC) at regular time intervals for patients with spinal cord injuries; however, many patients experience difficulties. Performing time-based CIC outside the home is a significant burden for patients. In this study, we aimed to overcome the limitations of the current guidelines by developing a digital device to monitor bladder
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Improving Foley Catheter Insertion Procedure by Developing Foley Introducer: A 100-Year Overdue Innovation. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-05-31 Khae Hawn Kim,Kyung Jin Chung
PURPOSE Foley catheter (FC) insertion is very basic yet one of the most widely performed procedures all across the fields of medicine. Since FC was first introduced in 19020's, no significant improvement has been made in view of methodology, despite the inconvenience associated with cumbersome preparation, procedure, and the patients' discomfort with having to have their genitalia exposed. We developed
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Intravesical Bladder Treatment and Deep Learning Applications to Improve Irritative Voiding Symptoms Caused by Interstitial Cystitis: A Literature Review. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-05-31 Yongwon Cho,Seunghyun Youn
Our comprehension of interstitial cystitis/painful bladder syndrome (IC/PBS) has evolved over time. The term painful bladder syndrome, preferred by the International Continence Society, is characterized as "a syndrome marked by suprapubic pain during bladder filling, alongside increased daytime and nighttime frequency, in the absence of any proven urinary infection or other pathology." The diagnosis
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Transfer Learning for Effective Urolithiasis Detection. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-05-31 Hyoung-Sun Choi,Jae-Seoung Kim,Taeg-Keun Whangbo,Khae Hawn Kim
PURPOSE Urolithiasis is a common disease that can cause acute pain and complications. The objective of this study was to develop a deep learning model utilizing transfer learning for the rapid and accurate detection of urinary tract stones. By employing this method, we aim to improve the efficiency of medical staff and contribute to the progress of deep learning-based medical image diagnostic technology
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The Metaverse for Healthcare: Trends, Applications, and Future Directions of Digital Therapeutics for Urology. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-05-24 Eun Joung Kim,Jung Yoon Kim
In recent years, the emergence of digital therapeutics as a novel approach to managing conditions has garnered significant attention. This approach involves using evidence-based therapeutic interventions that are facilitated by high-quality software programs to treat, manage, or prevent medical conditions. The incorporation of digital therapeutics into the Metaverse has increased the feasibility of
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Development and Evaluation of Urolithiasis Detection Technology Based on a Multimethod Algorithm. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 Jong Mok Park, Sung-Jong Eun, Yong Gil Na
In this paper, we propose an optimal ureter stone detection model utilizing multiple artificial intelligence technologies. Specifically, the proposed model of urinary tract stone detection merges an artificial intelligence model and an image processing model, resulting in a multimethod approach.
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Effects of Age and Multiple Vaginal Births on Lower Urinary Tract Structure and Function in Nonhuman Primates. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 J Koudy Williams, Karl-Erik Andersson, Shannon Lankford, Gopal Badlani
The relative roles of urinary sphincter damage, aging, and childbirth in stress urinary incontinence (SUI), have not been established. This study was performed to elucidate the roles of these factors.
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The Innovative Approach in Functional Bladder Disorders: The Communication Between Bladder and Brain-Gut Axis. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 Jiwon Jung, Aram Kim, Seung-Hoon Yang
Functional bladder disorders including overactive bladder and interstitial cystitis may induce problems in many other parts of our body such as brain and gut. In fact, diagnosis is often less accurate owing to their complex symptoms. To have correct diagnosis of these diseases, we need to understand the pathophysiology behind overlapped clinical presentation. First, we focused on reviewing literatures
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A Velocity-Based Approach to Noninvasive Methodology for Urodynamic Analysis. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 Lorenzo Lotti, Pietro Spatafora, Vincenzo Li Marzi, Giulio Nicita, Enio Paris, Sergio Serni
To date, invasive urodynamic investigations have been used to define most terms and conditions relating to lower urinary tract symptoms. This invasiveness is almost totally due to the urethral catheter. In order to remove this source of discomfort for patients, the present study investigated a noninvasive methodology able to provide diagnostic information on bladder outlet obstruction or detrusor underactivity
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Effectiveness of Fluid and Caffeine Modifications on Symptoms in Adults With Overactive Bladder: A Systematic Review. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 Jeongok Park, Hyojin Lee, Youngkyung Kim, Christine Norton, Sue Woodward, Sejeong Lee
Overactive bladder (OAB) is prevalent in men and women and negatively impacts physical and psychological health. Fluid and caffeine intake modifications, which are lifestyle modification interventions, are simple methods to manage OAB. However, studies that synthesized both interventions and found scientific evidence are scarce. This review aimed to synthesize scientific evidence on whether fluid and
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Updates of Overactive Bladder in Pediatrics. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 Jisung Shim, Mi Mi Oh
Overactive bladder (OAB) is clinically defined as urinary urgency with or without urinary incontinence. It is associated with daytime frequency or constipation and has a prevalence of approximately 5%-12% among 5- to 10-year-olds. The appropriate functional exchange between the pontine micturition center, periaqueductal gray matter, and prefrontal cortex is important for proper micturition control
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Decreased Expression of Urethral Caveolin-1, -2, and -3 in the Rat Model of Overactive Bladder: Potential Mediator of Functional Interaction of Urethra and Urinary Bladder. Int. Neurourol. J. (IF 2.3) Pub Date : 2023-03-31 Hyun Jin Cho, Han-Yi Jiao, Sun-Ouck Kim
To investigate the effect of detrusor overactivity (DO) on the urethral expression of caveolin (CAV)-1, -2, and -3 of urethra in an animal model of cyclophosphamide (CYP)-induced cystitis rat.