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PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway Cytotechnology (IF 2.2) Pub Date : 2024-04-22 Changren Zhu, Cuimei Wang, Xiaodong Wang, Shuangshuang Dong, Qing Xu, Jun Zheng
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Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling Cytotechnology (IF 2.2) Pub Date : 2024-04-17 Zunguo Pu, Fei Ge, Yaqing Zhou, Aiming Liu, Chao Yang
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Stable two- and three-dimensional cholangiocyte culture systems from extrahepatic bile ducts of biliary atresia patients: use of structural and functional bile duct epithelium models for in vitro analyses Cytotechnology (IF 2.2) Pub Date : 2024-04-08 Ai Shimamura, Mayumi Higashi, Kazuya Nagayabu, Shigeru Ono
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The effect of TFAP2A/ANXA8 axis on ferroptosis of cervical squamous cell carcinoma (CESC) in vitro Cytotechnology (IF 2.2) Pub Date : 2024-04-08 Yuehua Sheng, Huiqing Ding, Jiaqing Zhou, Yuejing Wu, Kejun Xu, Fan Yang, Yongming Du
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Degranulation of RBL-2H3 rat basophilic leukemia cells is synergistically inhibited by combined treatment with nobiletin and lactoferrin Cytotechnology (IF 2.2) Pub Date : 2024-04-04 Kaho Miyake, Mamoru Tanaka, Sayaka Yokoyama, Lu Rui, Ayaka Koida, Hana Kozai, Takeaki Okamoto
The aim of this study was to elucidate the anti-allergic effects of polymethoxyflavonoids in combination with milk proteins and the mechanism of inhibition. Three polymethoxyflavonoids and two milk proteins were exposed to the rat basophilic leukemia cell line RBL-2H3. β-hexosaminidase was used as an indicator of degranulation inhibition. The mechanism of inhibition was examined by measuring intracellular
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LncRNA MIR181A2HG negatively regulates human keratinocytes proliferation by binding SRSF1 Cytotechnology (IF 2.2) Pub Date : 2024-03-26
Abstract Psoriasis is a common chronic inflammatory skin disease. Abnormal proliferation of keratinocytes plays an important role in the pathogenesis of psoriasis. Long non-coding RNAs (lncRNAs) are involved in the regulation of a variety of cell biological processes. The purpose of this study was to investigate the potential role of lncRNA MIR181A2HG in the proliferation of human keratinocytes. qRT-PCR
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Schizandrin A enhances the sensitivity of gastric cancer cells to 5-FU by promoting ferroptosis Cytotechnology (IF 2.2) Pub Date : 2024-03-25
Abstract Schizandrin A (Sch A) exert anticancer and multidrug resistance-reversing effects in a variety of tumors, but its effect on 5-fluorouracil (5-Fu) in gastric cancer (GC) cells remains unclear. The aim of the present study was to examine the resistance-reversing effect of Schizandrin A and assess its mechanisms in 5-Fu-resistant GC cells.5-Fu-sensitive GC cells were treated with 5-Fu and 5-Fu-resistant
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Anti-cancer drug-mediated increase in mitochondrial mass limits the application of metabolic viability-based MTT assay in cytotoxicity screening Cytotechnology (IF 2.2) Pub Date : 2024-03-21 Abhishek Kumar, Yogesh Rai, Anant Narayan Bhatt
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Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes Cytotechnology (IF 2.2) Pub Date : 2024-02-27 Tomoko Furukawa, Chisako Yokono, Yoshihiro Nomura
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LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA Cytotechnology (IF 2.2) Pub Date : 2024-02-20 Bo Guo, Shengzhe Yan, Lei Zhai, Yanzhen Cheng
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Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis Cytotechnology (IF 2.2) Pub Date : 2024-02-16 Kei Tsukui, Masamitsu Suzuki, Miyu Amma, Yoshihiro Tokudome
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miR-92a-3p promotes pulmonary fibrosis progression by regulating KLF2-mediated endothelial-to-mesenchymal transition Cytotechnology (IF 2.2) Pub Date : 2024-02-15 Sisi Pang, Bo Chen, Yan Li, Shuangshuang Wu, Lei Chen
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Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells Cytotechnology (IF 2.2) Pub Date : 2024-02-15
Abstract Cirrhosis is a familiar end-stage of multiple chronic liver diseases. The gene-modified mesenchymal stem cells (MSCs) have become one of the most promising schemes for the treatment of cirrhosis. MSCs exhibit their therapeutic role mainly by secreting hepatocyte growth factor (HGF). The aim of this research was to probe the anti-fibrosis role of exosomes secreted by HGF modified-mouse adipose
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NEAT1 promotes the progression of prostate cancer by targeting the miR-582-5p/EZH2 regulatory axis Cytotechnology (IF 2.2) Pub Date : 2024-02-14 Weiqiang Xu, Yu Wu, Guoxi Zhang
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Selective elimination of tumorigenic cells from mixed culture of normal and tumorigenic cells using hybrid liposomes aimed at realizing of cell therapy Cytotechnology (IF 2.2) Pub Date : 2024-02-13
Abstract While induced pluripotent stem (iPS) cells are expected to be a cell source for regenerative medicine, they also have tumorigenic properties owing to their proliferative potential. During the manufacturing of regenerative medicine products, undifferentiated iPS cells and malignant transformed cells may be mixed in the cell culture population. Therefore, it is essential to eliminate tumorigenic
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Fructobacillus fructosus OS-1010 strain stimulates intestinal cells to secrete exosomes that activate muscle cells Cytotechnology (IF 2.2) Pub Date : 2024-01-26
Abstract Fructobacillus is a lactic-acid bacterium recently identified in fructose-rich environments. Fructobacillus is also known to exhibit unusual growth characteristics due to an incomplete gene encoding alcohol/acetaldehyde hydrogenase, which results in an imbalance in the nicotinamide adenine mononucleotide (NAD+)/NADN levels. Recently, the addition of d-fructose to the culture medium of Fructobacillus
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Evodiamine ameliorates intervertebral disc degeneration through the Nrf2 and MAPK pathways Cytotechnology (IF 2.2) Pub Date : 2023-12-27
Abstract Degradation of extracellular matrix (ECM), reactive oxygen species (ROS) production, and inflammation are critical players in the pathogenesis of intervertebral disc degeneration (IDD). Evodiamine exerts functions in inhibiting inflammation and maintaining mitochondrial antioxidant functions. However, the biological functions of evodiamine and its related mechanisms in IDD progression remain
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Activation of the Nrf2/HO-1 axis by glutaredoxin 2 overexpression antagonizes vascular endothelial cell oxidative injury and inflammation under LPS exposure Cytotechnology (IF 2.2) Pub Date : 2023-12-11 Yuna Liu, Jinlin Gong, Qing Wang, Na Wei, Lei Zhao, Zhenan Wu
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MiR-4763-3p accelerates lipopolysaccharide-induced cardiomyocyte apoptosis and inflammatory response by targeting IL10RA Cytotechnology (IF 2.2) Pub Date : 2023-12-01 Lei Yang, Qian Dai, Xiaoming Bao, Wang Li, Jie Liu
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Effects of wasp (Vespa crabro) nest extracts on virus replication of Autographa californica nuclear polyhedrosis virus on Spodoptera frugiperda cell culture Cytotechnology (IF 2.2) Pub Date : 2023-11-24 Alev Çaldaş, Ceren Börçek Kasurka, Ömer Ertürk
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Evaluation of the PrimeFlow RNA assay as a method of detection of SARS-CoV-2 single and dual Infections Cytotechnology (IF 2.2) Pub Date : 2023-11-24 Shollie M. Falkenberg, Alexa Buckley, Paola Boggiatto
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Fish cell line: depositories, web resources and future applications Cytotechnology (IF 2.2) Pub Date : 2023-11-27 Murali S. Kumar, Vijay Kumar Singh, Akhilesh Kumar Mishra, Basdeo Kushwaha, Ravindra Kumar, Kuldeep Kumar Lal
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Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia Cytotechnology (IF 2.2) Pub Date : 2023-11-28 Cagla Kiser, Ceren Perihan Gonul, Sermin Genc
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Pulsed electrical stimulation and amino acid derivatives promote collagen gene expression in human dermal fibroblasts Cytotechnology (IF 2.2) Pub Date : 2023-11-09 Hiroya Urabe, Ryuji Akimoto, Shohei Kamiya, Katsu Hosoki, Hideyuki Ichikawa, Toshio Nishiyama
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Nitric oxide-cyclic GMP role in Ang II induced hyperpolarization in bovine aortic endothelium cell line (BAE-1) Cytotechnology (IF 2.2) Pub Date : 2023-11-02 Chinar M. Mohammed, Omar A. M. Al-Habib
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Study on the mechanism of CXCL12/CXCR4-axis-mediated upregulation of IL-8 and IL-6 on the biological function of acute T lymphocyte leukaemia cells Cytotechnology (IF 2.2) Pub Date : 2023-10-28 Liping Zhou, Hui Zhao, Chao Zhang, Zhe Chen, Dong Li, Guanglei Qian
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Construction of a novel kinetic model for the production process of a CVA6 VLP vaccine in CHO cells Cytotechnology (IF 2.2) Pub Date : 2023-10-27 Zhou Xing, Thao Bich Nguyen, Guirong Kanai-Bai, Noriko Yamano-Adachi, Takeshi Omasa
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Exosome-mediated circGMPS facilitates the development of gastric cancer cells through miR-144-3p/PUM1 Cytotechnology (IF 2.2) Pub Date : 2023-10-20 Yuexin Zhang, Wenrui Xie, Wenhong Zheng, Xiaoying Qian, Chengwei Deng
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PRPF19 functions in DNA damage repair and gemcitabine sensitivity via regulating DDB1 in bladder cancer cells Cytotechnology (IF 2.2) Pub Date : 2023-10-05 Jingjiang Yu, Shuxiong Ge
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Reconstruction of ovarian follicular-like structure by recellularization of a cell-free human ovarian scaffold with mouse fetal ovarian cells Cytotechnology (IF 2.2) Pub Date : 2023-10-06 Maryam Nezhad Sistani, Saeed Zavareh, Mojtaba Rezazadeh Valojerdi, Mojdeh Salehnia
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Effective methods for immobilization of non-adherent Pv11 cells while maintaining their desiccation tolerance Cytotechnology (IF 2.2) Pub Date : 2023-10-06 Hiroto Fuse, Takahiro Kikawada, Richard Cornette
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Optimization of adaptation parameters from adhesion cell culture in serum-containing media to suspension in chemically defined media by superlative box design Cytotechnology (IF 2.2) Pub Date : 2023-09-29 Wanyue Cui, Shijie Liu
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The m6A reader IGF2BP1 manipulates BUB1B expression to affect malignant behaviors, stem cell properties, and immune resistance of non-small-cell lung cancer stem cells Cytotechnology (IF 2.2) Pub Date : 2023-09-21 Shuo Hu, Xi Yan, Wen Bian, Bin Ni
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Hypoxia-induced the upregulation of NDUFA4L2 promoted colon adenocarcinoma progression through ROS-mediated PI3K/AKT pathway Cytotechnology (IF 2.2) Pub Date : 2023-09-19 Nianyuan Ye, Yibo Wang, Peng Jiang, Huaji Jiang, Wei Ding, Zheng Zhang, Cheng Xi
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Deciphering variations in the endocytic uptake of a cell-penetrating peptide: the crucial role of cell culture protocols Cytotechnology (IF 2.2) Pub Date : 2023-09-08 Joshua Diaz, Jean-Philippe Pellois
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MiR-224-5p inhibits osteoblast differentiation and impairs bone formation by targeting Runx2 and Sp7 Cytotechnology (IF 2.2) Pub Date : 2023-09-05 Siyang Ding, Yunfei Ma, Jiashu Yang, Yuting Tang, Yucui Jin, Lingyun Li, Changyan Ma
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Lobetyolin inhibits cell proliferation and induces cell apoptosis by downregulating ASCT2 in gastric cancer Cytotechnology (IF 2.2) Pub Date : 2023-08-19 Lin Cheng, Haoqing Zhai, Juan Du, Gang Zhang, Gan Shi
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H3K27 acetylation-induced FSTL1 upregulation by P300/RUNX1 co-activation exacerbated autophagy-mediated neuronal damage and NF-κB-stimulated inflammation in Alzheimer’s disease Cytotechnology (IF 2.2) Pub Date : 2023-08-04 Dongmei Dai, Junzheng Xie, Yun Zheng, Fangbin Chen, Bin Zhao, Li Miao
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New high-throughput screening method for Chinese hamster ovary cell lines expressing low reduced monoclonal antibody levels: application of a system controlling the gas phase over cell lysates in miniature bioreactors and facilitating multiple sample setup Cytotechnology (IF 2.2) Pub Date : 2023-07-21 Tsuyoshi Yamaguchi, Mie Fukuda, Yuichi Matsumoto, Takaaki Mori, Shinsuke Kikuchi, Ryuma Nagano, Koichi Yamamoto, Kaori Wakamatsu
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Effect of milk and whey on proliferation and differentiation of placental stromal cells Cytotechnology (IF 2.2) Pub Date : 2023-07-17 Bircan Boga, Merve Akbulut, Erkan Maytalman, Ilknur Kozanoglu
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Effect assessment of a type of xeno-free and serum-free human adipose-derived mesenchymal stem cells culture medium by proliferation and differentiation capacities Cytotechnology (IF 2.2) Pub Date : 2023-07-11 Shanshan Chen, Li Meng, Shanshan Wang, Yan Xu, Wenbin Chen, Jianfeng Wei
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Assessing MTT and sulforhodamine B cell proliferation assays under multiple oxygen environments Cytotechnology (IF 2.2) Pub Date : 2023-07-05 Ming Yao, Glenn Walker, Michael P. Gamcsik
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Identification of differentially expressed miRNAs and mRNAs associated with the regulation of breast cancer via in silico and in vitro methods Cytotechnology (IF 2.2) Pub Date : 2023-07-03 Pelin Telkoparan-Akillilar, Dilek Cevik
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Development of a cell line from skeletal trunk muscle of the fish Labeo rohita Cytotechnology (IF 2.2) Pub Date : 2023-06-01 Mukunda Goswami, Nevil Pinto, B. S. Yashwanth, A. Sathiyanarayanan, Reza Ovissipour
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DEHP exposure impairs human skeletal muscle cell proliferation in primary culture conditions: preliminary study Cytotechnology (IF 2.2) Pub Date : 2023-05-31 Elizabeth Brassea-Pérez, Vanessa Labrada-Martagón, Claudia J. Hernández-Camacho, Ramón Gaxiola-Robles, José Pablo Vázquez-Medina, Tania Zenteno-Savín
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Fabricating the cartilage: recent achievements Cytotechnology (IF 2.2) Pub Date : 2023-05-26 Nesa Fani, Maria Peshkova, Polina Bikmulina, Reihaneh Golroo, Peter Timashev, Massoud Vosough
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Bioinformatics analysis of synovial fluid-derived mesenchymal stem cells in the temporomandibular joint stimulated with IL-1β Cytotechnology (IF 2.2) Pub Date : 2023-05-09 Yiting Lou, Ran Tao, Xiaoyan Weng, Suzhen Sun, Yong Yang, Binbin Ying
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M2 macrophage-derived extracellular vesicles augment immune evasion and development of colorectal cancer via a circRNA_CCDC66/microRNA-342-3p/metadherin axis Cytotechnology (IF 2.2) Pub Date : 2023-04-19 Linfeng Fan, Guofeng Xu, Xiangfu Zeng
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An agarose-alginate microfluidic device for the study of spheroid invasion, ATRA inhibits CAFs-mediated matrix remodeling Cytotechnology (IF 2.2) Pub Date : 2023-04-11 Mohammad Reza Nasiraee, Shabnam Shahrivari, Soheila Sayad, Hoda Mahdavi, Neda Saraygord‐Afshari, Zeinab Bagheri
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Reconstruction of bone marrow microenvironment for expansion of hematopoietic stem cells by a histone deacetylase inhibitor Cytotechnology (IF 2.2) Pub Date : 2023-04-07 Maryam Haj Ali Askari, Majid Shahabi, Amir Asri Kojabad, Mahin Nikougoftar Zarif
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Disease-related biomarkers as experimental endpoints in 3D skin culture models Cytotechnology (IF 2.2) Pub Date : 2023-04-03 Deepa Chaturvedi, Swarali Paranjape, Ratnesh Jain, Prajakta Dandekar
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Targeting a novel circITCH/miR-421/BTG1 axis is effective to suppress the malignant phenotypes in hepatocellular carcinoma (HCC) cells Cytotechnology (IF 2.2) Pub Date : 2023-04-03 Xiaodong Li, Xuedong Yin, Heyi Bao, Chang Liu
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GSK-3α/β and MEK inhibitors assist the microenvironment of tumor initiation Cytotechnology (IF 2.2) Pub Date : 2023-04-01 Ghmkin Hassan, Said M. Afify, Maram H. Zahra, Hend M. Nawara, Kazuki Kumon, Yoshiaki Iwasaki, David S. Salomon, Akimasa Seno, Masaharu Seno
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Effects of various disaccharide adaptations on recombinant IgA1 production in CHO-K1 suspension cells Cytotechnology (IF 2.2) Pub Date : 2023-03-16 John Benson D. Choa, Tadahiro Sasaki, Hiroyuki Kajiura, Kazuyoshi Ikuta, Kazuhito Fujiyama, Ryo Misaki
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Immunomodulatory effect of human dedifferentiated fat cells: comparison with adipose-derived stem cells Cytotechnology (IF 2.2) Pub Date : 2023-02-24 Yan Lin, Dali Mu
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Molecular chaperones HSP40, HSP70, STIP1, and HSP90 are involved in stabilization of Cx43 Cytotechnology (IF 2.2) Pub Date : 2023-02-03 Li An, Hong Gao, Yi Zhong, Yanqiu Liu, Ying Cao, Jing Yi, Xiang Huang, Chunlei Wen, Rui Tong, Zhijun Pan, Xu Yan, Meiyan Liu, Shengzhao Wang, Xue Bai, Hao Wu, Tingju Hu
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Carboxymethyl chitosan regulates oxidative stress and decreases the expression levels of tumor necrosis factor α in macrophages induced by wear particles Cytotechnology (IF 2.2) Pub Date : 2023-01-12 Feng Liu, Hao Pan, Ming Xie, Yingzhen Wang, Hao Xu
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Functional improvements in β-conglycinin by preparing edible bioconjugates with ε-polylysine and dextran Cytotechnology (IF 2.2) Pub Date : 2023-01-05 Tadashi Yoshida, Ikumi Hamaji, Takeshi Hashimoto, Takuya Matsumoto, Makoto Hattori
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Identification of cell culture contamination by an unusual species of Mycoplasma related to the M. mycoides cluster Cytotechnology (IF 2.2) Pub Date : 2023-01-04 Jose Antonio Carrillo-Ávila, R. Aguilar-Quesada, G. Ligero, S. Panadero-Fajardo, M. V. Santos-Pírez, P. Catalina
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Connexin 45 is a novel suppressor of melanoma metastasis Cytotechnology (IF 2.2) Pub Date : 2022-12-17 Mikako Saito, Naruwa Tokunaga, Toshiki Saito, Tomohiro Hatakenaka, Tomonori Sasaki, Nahoko Matsuki, Seiya Minagawa