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Rare Mutations V453X and Y847X in the MYBPC3 Gene Do Not Lead to a Severe Form of Hypertrophic Cardiomyopathy in the Russian Population Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 A. L. Klass, N. S. Krylova, A. V. Lysenko, I. N. Vlasov, M. Yu. Maslova, G. I. Salagaev, E. A. Kovalevskaya, N. G. Poteshkina, M. I. Shadrina, P. A. Slominsky, E. V. Filatova
Abstract Mutations in the MYBPC3 gene are currently believed to lead to the development of hypertrophic cardiomyopathy (HCM) in the majority of genetically determined cases. However, despite many years of research, both in worldwide and in Russia in particular, the genetic landscape of HCM is still insufficiently studied. Moreover, the insufficient study of genetically determined cases of HCM in the
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The Cytotoxic Activity of Phenazine Compounds from Pseudomonas chlororaphis subsp. aurantiaca against the HeLa Cell Line Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 A. A. Zhyzneyskaya, A. A. Lukashevich, N. P. Maksimova, E. G. Veremeenko
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Monitoring the Spread of SARS-CoV-2 Gene Variants in Sverdlovsk and Chelyabinsk Oblasts and Perm Krai Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 A. E. Chernysheva, I. A. Korotkova, E. V. Bolgarova, A. Yu. Markaryan, A. V. Semenov
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Molecular Identification of Leptospira interrogans and Its Treatment with Andrographis paniculata Extract Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 Abirami Madhaiyan, V. Muthumani, E. Angel Jemima, K. Rubika, V. Bharathi, N. Parameswari, V. Kowsalya Devi, K. Ramesh, P. Poongothai
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Regulatory Non-Coding RNAs in Crops Health and Disease Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 Patrick Ferreira, Pedro A. Casquero, Altino Choupina
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Comparative Analysis of Influenza Viruses Isolated from Early and Severe Cases in Epidemic Seasons before and during the COVID-19 Pandemic in Russia (2019–2023) Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 N. D. Boldyrev, A. S. Panova, N. P. Kolosova, A. V. Danilenko, S. V. Svyatchenko, G. S. Onkhonova, V. Yu. Marchenko, A. B. Ryzhikov
Abstract The influenza virus is one of the most dangerous causative agents of respiratory diseases, and its study is important for epidemiological control, especially in the case of cocirculation with SARS-CoV-2. Comparative analysis of influenza viruses isolated from early and severe cases in epidemic seasons before and during the COVID-19 pandemic in Russia. The article is based on the results of
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Association of Mutations in gyrA Gene with Resistance to Fluoroquinolones in Clinical Isolates of Multidrug-Resistant Mycobacterium tuberculosis Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 Hanieh Bagherifard, Mitra Salehi, Mona Ghazi
Abstract The purpose of the present study was to evaluate the association of mutations inside and outside quinolone-resistance determining region (QRDR) of gyrA gene with resistance to fluoroquinolones, particularly levofloxacin (LFX), moxifloxacin (MFX), ofloxacin (OFX), and ciprofloxacin (CIP). Therefore, a total of 255 clinical isolates of Mycobacterium tuberculosis were tested for drug susceptibility
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Historical Isolates of Semliki Forest and Chikungunya Viruses and Their Virological Characteristic, Whole-Genome Sequences, and Phylogeny Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 T. P. Mikryukova, E. V. Protopopova, A. S. Mezhevalova, R. B. Bayandin, Yu. A. Khoroshavin, A. N. Shvalov, O. S. Taranov, T. V. Tregubchak, V. A. Ternovoi, V. B. Loktev
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Cassette Construction and Co-Expression of NA and F Proteins of H1N1 Influenza Virus and Newcastle Disease Virus in Saccharomyces cerevisiae Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 A. Seyed Hamzehzadeh, A. Hesampour
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Phylogenetic Analysis and Frequency Estimation of HTLV-1 Virus in Hemophilic Patients Refer to Iranian Comprehensive Hemophilia Care Center (ICHCC) Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-03-20 Tina Taikandi, Navid Momenifar, Ali Namvar, Alireza Azizi Saraji, Mehdi Norouzi, Cobra Razavi Pashabayg
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Identification of Antimicrobial Resistance Genes and Drug Targets in Antibiotic-Resistant Clostridioides difficile Clinical Isolates Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 Ali Mohammed Al-Rawe, Yousif Ibrahem Yousif, Ousama Khalaf Ghareeb Al-Jomaily, Semaa A. Shaban, Ahmed AbdulJabbar Suleiman
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Genetic Diversity of Rickettsiae in Dermacentor spp. Ticks on the Territory of Western Siberia and Northern Kazakhstan Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 V. I. Yakubovskij, Y. P. Igolkina, A. Y. Tikunov, V. V. Panov, V. V. Yakymenko, A. G. Zhabykpayeva, T. I. Epikhina, V. A. Rar
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Genetic Variations in Spike Protein: Linking SARS-CoV-2 Variants to Clinical Outcomes Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 Peshnyar M. A. Rashid, Gaza F. Salih
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Directed Neuronal Differentiation of SH-SY5Y Human Neuroblastoma Cells on 2D Matrices Containing Recombinant Spidroins Modified with Cell Adhesion Peptides Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 O. D. Kurko, L. I. Davydova, K.V. Sidoruk, I. A. Grivennikov, V. G. Debabov, V. G. Bogush, V. Z. Tarantul, O. V. Dolotov
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Adjuvant Effects of Deleting Hypervariable Domains of FliC of Escherichia coli Nissle 1917 Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 Shuang Li, Yongjun Deng, Bingming Ou, Ming Wen, Ying Yang, Guilan Wen
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The Role of IL-10 G-1082A Polymorphism in Hypertrophy of the Pharyngeal Tonsil Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 S. S. Shilin, Y. I. Emets, E. A. Spirin, K. S. Gusev, A. A. Antonyan, A. S. Dolgonovskaya, D. V. Piskarev, V. I. Popadyuk, I. V. Kastyro, I. B. Ganshin, S. M. Vasyakova
Hypertrophy of the pharyngeal tonsil (HPT) is considered one of the most common diseases of the ENT organs. The aim of the present study was to investigate the role of interleukin 10 (IL-10) gene polymorphism and infections caused by human herpesviruses 6 (HHV6), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) in children with HPT. The study included 106 children with HPT and 38 healthy children
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The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2024-01-13 S. A. Partevian, D. R. Safina, M. M. Rudenok, I. N. Rybolovlev, E. I. Semenova, M. I. Shadrina, P. A. Slominsky, S. V. Kostrov, A. Kh. Alieva
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Prevalence of Human Papilloma Virus in the Patients with Oral Cancer Referred to Shiraz Teaching Hospital during 2016–2017 Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-12-01
Abstract Introduction: Cancer is one of the leading causes of death worldwide and oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity in which there is a poor prognosis. Viruses, including Human papillomavirus (HPV), play an important role in the etiology of this cancer. The aim of this study was to evaluate the prevalence of HPV in patients with oral cancer in Shiraz
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Application of A29L Protein Specific Monoclonal Antibodies A-A29L_MPoxV for Monkeypox Diagnosis Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-12-01
Abstract The spread of the disease caused by monkeypox virus (MPox) since 2022 has shown the urgency of developing countermeasures. The development of modern methods of clinical laboratory diagnostics of MPox contributes to this. Enzyme-linked immunosorbent assay (ELISA) is an accessible and sensitive platform for developing diagnostic tools. Detection of MPox antigens using ELISA kits based on monoclonal
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Composition of Populations and Durations of Persistence of Bordetella pertussis Bacteria in Patients with Whooping Cough and Contact Persons Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 A. Yu. Medkova, E. G. Semin, S. V. Kulikov, Yu. V. Nesterova, I. V. Babachenko, L. N. Sinyashina, G. I. Karataev
Abstract Whooping cough still occupies a leading position in the group of controlled infectious diseases, despite worldwide mass vaccination. In recent decades, there has been a significant increase in the incidence of whooping cough and the spread of atypical forms among adolescents and adults. It has been proposed that the formation of an anthropogenic source of infection evolves due to Bordetella
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Lactobacillus crispatus and Human Herpes Simplex Virus-2, an In Vitro Study Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 Mehdi Moazzami Goudarzi, Mohammad Reza Fazeli, Abbas Akhavan Sepahi, Akram Eidi
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Recombinant RBD of the SARS-CoV-2 Spike Protein: Production in Escherichia coli Cells, Binding to Antibodies, and Antiviral Activity Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 M. S. Gromova, A. V. Gromov, T. M. Grunina, A. M. Lyashchuk, Z. M. Galushkina, M. E. Subbotina, I. B. Esmagambetov, E. I. Ryabova, V. V. Prokofiev, A. V. Kovyrshina, A. A. Ilyukhina, A. Y. Shelkov, A. S. Karyagina, V. G. Lunin
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Hantaviruses in Populations of Voles in Siberia Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 L. N. Yashina, S. A. Abramov, N. A. Smetannikova, B. S. Malyshev, T. A. Dupal, A. V. Krivopalov
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Specifics of the Taxonomic Composition of Bacterial Microflora in the Respiratory Microbiome of Patients with Chronic Dust Bronchitis Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 S. A. Paradnikova, V. G. Druzhinin, E. D. Baranova, P. S. Demenkov, A.V. Larionov
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Monoclonal Antibody Panel for Hepatitis B Virus Genotype and HBsAg Subtype Identification: Results Obtained for Blood-Serum Samples from Three Regions of Russia Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 L. V. Bezuglova, E. I. Sergeeva, L. Yu. Voevodskaya, E. E. Lysykh, N. V. Polovitsa, I. V. Deliy, M. K. Ivanov, I. G. Netesova, S. V. Netesov
Abstract We previously developed a technique that uses the anti-HBs monoclonal antibody panel (MAbs) to determine the major variants of hepatitis B virus (HBV) genotypes and surface antigen (HBsAg) subtypes circulating in the Russian Federation: D/ayw2, D/ayw3, A/adw2, C/adrq+. To identify HBV genotypes and HBsAg subtypes in HBsAg-positive blood-serum samples of patients with chronic HBV infection
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Pogo DNA Transposons in the Genomes of the Aurelia Genus Jellyfish Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 Y. N. Ulupova, M. V. Puzakov, L. V. Puzakova
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RNA N6-Methyladenosine Pathway Writer Genes Expression Levels and Clinical Severity of Infection in Covid-19 Patients Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-12 Badel Arslan, Sevgi Baltacı, Burcu Bayyurt, Nil Özbilum Sahin, Murat Eser Akyurek, Mehmet Bakır, Serdal Arslan
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The Effect of the flhB Plasmid Gene of the Flagellar Export Component on Flagellation and Motility in Azospirillum Bacteria Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-01
Abstract The effect was analyzed of the flhB2 gene, which is located on the AZOBR_p4 (AZOBR_p410073 gene) plasmid in Azospirillum baldaniorum Sp245 and on the ABSP7_p3 (AMK58_26270 gene) plasmid in A. brasilense Sp7 and codes for the FlhB protein, a flagellar export component that ensures flagellin assembly, flagellation, and motility in these bacteria. We used A. baldaniorum strain Sp245, its Fla–
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Benefits of Using the CRISPR/Cas9 System for the Correction of Genetic Mutations Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-09-01
Abstract The discovery of the CRISPR/Cas9 gene scissors technology was a breakthrough in the development of gene therapy methods and attracted the attention of the entire scientific community. This technology provides prospects for the treatment of many neurodegenerative diseases and cancers that were previously considered almost incurable. To date, the mechanisms of the development and progression
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Nitrosonium Cation NO+ Inhibits Nitric-Oxide Functions in the Regulation of Pseudomonas aeruginosa Biofilm Formation Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 S. V. Vasilieva, N. V. Alekseeva, Yu. M. Romanova, A. F. Vanin
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Genetic Diversity of Listeria Detected in the Production Environment of Meat Processing Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 O. L. Voronina, N. N. Ryzhova, E. I. Aksenova, M. S. Kunda, A. V. Kutuzova, T. I. Karpova, Yu. K. Yushina, I. S. Tartakovsky
Abstract The safety of food production as concerns Listeria is the key to the sanitary wellbeing of manufactured products. Molecular-genetic methods for the analysis of Listeria, including whole-genome sequencing, are effective in monitoring persistent contaminants and in the epidemic investigation of cases of foodborne infections. They have been adopted in the European Union, United States, and Canada
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Prevalence of MYBPC3 Gene Mutations in Russian Patients with Hypertrophic Cardiomyopathy Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 A. L. Klass, N. S. Krylova, A. V. Lysenko, I. N. Vlasov, M. Yu. Maslova, G. I. Salagaev, E. A. Kovalevskaya, N. G. Poteshkina, M. I. Shadrina, P. A. Slominsky, E. V. Filatova
Abstract Hypertrophic cardiomyopathy (HCM) is considered the most common inherited heart disease. HCM is a highly heterogeneous disease from the genetic point of view. However, the cause of the disease remains unclear, despite the large number of pathogenic variants detected in more than a quarter of patients. Therefore, studying the prevalence of pathogenic variants associated with HCM especially
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New Genetic Variants of the Cholera Agent and Their Distribution in Endemic Countries and Russia Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 N. I. Smirnova, D. A. Rybal’chenko, N. A. Plekhanov, Yu. V. Lozovsky, A. V. Fedorov, V. V. Kutyrev
Abstract In the course of the three waves of the seventh cholera pandemic, the genome of the pathogen has undergone significant changes, which resulted in the emergence of new genetic variants with a high pathogenic and epidemic in the last decade. The aim of this study is to investigate the genomic diversity of the cholera agent and the prevalence of new genetic variants both in cholera-endemic regions
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Proteomic Analysis in Microbiology Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 T. N. Sharov, D. V. Viktorov, A. V. Toporkov
Abstract Identification of microorganisms using the method of time-of-flight mass spectrometry has been widely used in various fields of microbiology for more than a decade. Despite its rather narrow area of applicability compared to other areas of proteomic analysis, this technology has developed significantly, making it a tangible competitor to the traditional bacteriological method. Basically, this
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Determining the Antibacterial Effect of Recombinant CpsA-CpsC-L-ACAN Fusion Peptide against E. coli and Staphylococcus aureus Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 Elmira Babakanrad, Taher Mohammadian, Davoud Esmaeili, Payam Behzadi
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In Pseudomonas syringae pv. phaseolicola NPS3121 the Regulator HrpL is Required for Siderophore Biosynthesis Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 Lizeth Guardado-Valdivia, Alejandra Chacón-López, José Luis Hernández-Flores, Luis Xoca-Orozco, Efigenia Montalvo-González, Selene Aguilera
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Autoimmune Haplotype AH8.1 Normalizes the Level of Tumor Necrosis Factor in the Blood Sera of Breast-Cancer Patients Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 T. F. Malivanova, T. A. Astrelina, I. V. Kobzeva, V. A. Nikitina, Yu. B. Suchkova, A. S. Ostashkin, D. Yu. Usupzhanova, E. I. Dobrovolskaya, V. A. Brunchukov, A. A. Rastorgueva, E. E. Lomonosova, E. S. Lubaeva, E. Yu. Kretova, N. G. Stepanyants, M. Yu. Sukhova, A. S. Samoilov
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The First Detection of Ebinur Lake Virus (Orthobunyavirus, Peribunyaviridae) in Russia Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-06-11 E. F. Avdiusheva, D. N. Luchinin, N. V. Borodai, A. S. Antonov, D. V. Ustinov, E. V. Molchanova, I. M. Shpak, D. V. Viktorov, A. V. Toporkov
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Differential Activity of Genes with IS630/TC1/MARINER Transposon Fragments in the Genome of the Ctenophore Mnemiopsis leidyi Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 M. V. Puzakov, L. V. Puzakova, Y. N. Ulupova
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Molecular-Genetic Mechanisms of Resistance to Antibiotic of the Pathogens in Patients with Thermal Burns and Infection Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 O. E. Khokhlova, I. V. Vladimirov, R. S. Kozlov, I. V. Lazareva, M. V. Edelstein, I. A. Larionova, A. V. Molodtsova, V. A. Avdeeva, N. K. Fursova, S. V. Sidorenko
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Diversity of NG-MAST and MLST Sequence Types in Russian Clinical Isolates of Neisseria gonorrhoeae Carrying the “Mosaic” Allele of the penA Gene Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 A. A. Kubanov, V. S. Solomka, M. V. Shpilevaya, D. A. Verbenko, D. G. Deryabin, I. D. Kandinov, E. I. Dementieva, D. A. Gryadunov, B. L. Shaskolskiy
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Genetic Diversity and Functional Status of the oipA Gene of Helicobacter pylori. Its Association with Genes of the Pathogenicity Island in Patients with Gastroduodenal Diseases in the Republic of Belarus Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 O. O. Yanovich, L. P. Titov, M. V. Doroshko
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Intercellular Interactions in the Tumor Stroma and Their Role in Oncogenesis Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 N. A. Lunina, D. R. Safina
Cancer remains the second leading cause of death in the world, despite significant improvements that have been made in diagnosis and therapy. This is partly due to the fact that most of the therapeutic agents that have been developed target tumor cells and ignore the tumor microenvironment. Currently, there is an increased interest in understanding the role of the microenvironment in tumor growth and
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Comparison of Fragments in Human Hemostatic Proteins That Mimics Fragments in Proteins of A/H1N1 Viruses and Coronaviruses Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 I. N. Zhilinskaya, V. A. Marchenko, E. P. Kharchenko
Abstract Objective: To compare the repertoire of proteins of the human hemostatic system and fragments mimicking these proteins in the proteins of influenza A/H1N1 viruses and coronaviruses. Material and methods. Influenza viruses A/H1N1 (A/Brevig Mission/1/18), A/St. Petersburg /RII04/2016 (H1N1)pdm09, coronaviruses SARS-CoV and SARS-CoV-2 (strain Wuhan-Hu-1) were used for comparative computer analysis
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Molecular Typing, Phenotypic and Genotypic Assessment of Antibiotic Resistance and Virulence Factors amongst the Staphylococcus aureus Bacteria Isolated from Raw Chicken Meat Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 Sepideh Karimi, Hassan Momtaz
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Detection of Tularemia Agent DNA by Loop Mediated Isothermal Amplification Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 I. Yu. Shchit, T. Yu. Kudryavtseva, A. N. Mokrievich, S. F. Biketov
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Plasma Long Non-Coding RNA ZFAS1 as a Potential Diagnostic Biomarker for HCV-Related Hepatocellular Carcinoma Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2023-03-20 Raghda Saad Zaghloul Taleb, Ahmed Elsayed Zeid, Maha Ahmed Nabil, Pacint Elsayed Moez
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Adaptive Immunity Systems of Bacteria: Association with Self-Synthesizing Transposons, Polyfunctionality Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 T. S. Ilyina
Microbial cells are constantly threatened by invasion of foreign genetic elements. There are many mobile genetic elements (MGEs), including viruses, plasmids, transposons, etc., that invade them. Such selective pressure provoked the production of various defense systems in bacteria and other microorganisms, such as restriction–modification, abortive infection, exclusion of phage superinfection, toxin–antitoxin
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COVID-19, Influenza, and Other Acute Respiratory Viral Infections: Etiology, Immunopathogenesis, Diagnosis, and Treatment. Part 2. Other Acute Respiratory Viral Infections Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 T. N. Ilyicheva, S. V. Netesov, V. N. Gureyev
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Epstein–Barr Virus: Evaluation of gp350 and EBNA2 Gene Variability Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 T. V. Solomai, M. V. Malakhova, E. A. Shitikov, D. A. Bespyatykh, V. A. Veselovskii, T. A. Semenenko, D. I. Smirnova, A. V. Gracheva, E. B. Faizuloev
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Single Nucleotide Polymorphisms in the U86 Gene of Human betaherpesvirus 6B Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 A. A. Vyazovaya, O. V. Narvskaya, V. E. Vedernikov, M. A. Nikolskiy
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Oral Delivery of SARS-CoV-2 DNA Vaccines Using Attenuated Salmonella typhimurium as a Carrier in Rat Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 Dan Zhu, Mengyue Mengyue, Aaodeng Qimuge, Bilige Bilige, Tegexi Baiyin, Temuqile Temuqile, Shana Chen, Siqin Borjigen, Huricha Baigude, Dezhi Yang
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The Efficiency of Bacteriophage Lytic Enzymes in the Course of Bacterial Ghost Generation Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 M. E. Platonov, A. S. Vagaiskaya, A. S. Trunyakova, D. V. Grinenko, V. N. Gerasimov, S. V. Dentovskaya, A. P. Anisimov
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Markers of Viral Hepatitis B in Blood–Plasma Samples of the Indigenous Population of the Far North of Russia. HBV Genotypes and HBsAg Subtypes Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 L. V. Bezuglova, L. P. Osipova, E. I. Sergeeva, I. V. Deliy, L. E. Tabikhanova, S. V. Netesov, I. G. Netesova
Hepatitis B is a major public health problem worldwide. The indigenous population of remote regions with harsh living conditions, such as the Far North of Russia, with possibly unique genetic mutations in the local strains of this pathogen, remains poorly studied. The aim of the study was to determine the prevalence of serological HBV markers in blood–plasma samples of the population of the Far North
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Efficacy of the Apoptotic Activity of CpsA-CpsC-L-ACAN Fusion Peptide against HeLa Cell Line Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-12-25 Elmira Babakanrad, Taher Mohammadian, Davoud Esmaeili, Payam Behzadi
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Genetic Aspects of Mechanosensitivity in the Alphaproteobacteria Azospirillum baldaniorum with Mixed Flagellation Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-10-03 S. S. Evstigneeva, D. I. Mokeev, L. P. Petrova, A. V. Shelud’ko
The aim of this work was to test the hypothesis that a putative multisensory hybrid histidine kinase—response regulator (HSHK–RR) and FlhB (a component of the type 3 secretion apparatus located in the basal body of Fla) encoded by Azospirillum baldaniorum Sp245 by adjacent chromosomal genes, are involved in mechanosensing and mechanotransduction. We used Sp245 strains and its Fla–Laf– mutant Sp245
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Production and Characterization of Rat Monoclonal Antibodies against the PAL Antigen of Legionella spp. Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-10-03 N. A. Zeninskaya, A. K. Riabko, M. A. Marin, T. I. Kombarova, I. P. Mitsevich, B. V. Yeruslanov, V. V. Firstova, I. G. Shemyakin
The purpose of this work was to obtain genus-specific monoclonal antibodies against the Legionella spp. recombinant PAL protein, which will subsequently allow to use them as a basis for the development of new express tests for pathogenic legionella detection. A short three-week immunization protocol for Wistar rats was used to generate rat–mouse heterohybridomas producing antibodies against PAL. Mouse
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Hepatitis B Virus Genotypes in Patients with Hepatitis D as Determined by the Panel of Their Own Development of Monoclonal Antibodies Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-10-03 L. V. Bezuglova, O. V. Isaeva, A. A. Karlsen, L. Y. Ilchenko, S. S. Sleptsova, A. A. Saryglar, V. A. Poryvaeva, Ya. D. Mosina, O. A. Agafonova, A. K. Mogilnykh, K. K. Kyuregyan, M. I. Mikhailov, S. V. Netesov, I. G. Netesova
Direct genotyping of hepatitis B virus (HBV) in samples from patients with hepatitis delta can be impossible due to an undetectable concentration of HBV DNA. A sufficient amount of surface HBV protein (HBsAg) in such samples makes it possible to determine HBV genotype using enzyme-linked immunosorbent assay (ELISA) of this antigen with a panel of monoclonal antibodies (MABs). The purpose of this paper
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Molecular-Genetic Monitoring of the Mycobacterium tuberculosis Population in Murmansk Oblast Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-10-03 A. A. Vyazovaya, N. Yu. Gavrilova, A. A. Gerasimova, A. O. Bychkova, I. Avadenii, E. V. Anikieva, N. S. Solovieva, V. Yu. Zhuravlev, I. V. Mokrousov, O. V. Narvskaya
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The Investigation of Clone and Expression of Butyrylcholinesterase in Pichia pastoris for Parathion Hydrolysis Molecul. Genet. Microbiol. Virol. (IF 0.5) Pub Date : 2022-10-03 M. Rastegar Shariat Panahi, M. Mirzaei, H. Tebyaniyan, S. Khodi, M. Heiat, A. M. Latifi