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Novel Chitosan Beeswax Matrix for Gastro-Retentive Delivery of Curcumin: A Promising Adjuvant Therapy for Helicobacter Infection J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-28 Nisrein Jaber, Mayyas Al-Remawi, Rami A. Abdel-Rahem
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Biosynthesis and Characterization of Silver Nanoparticle by Using Artocarpus altilis Fruit Extract for Its Biological Activity J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-27 Thasni PM, Abdul Vajid K, Najila Shirin U, Nivya K, Fathimath Shibila AP, Ilyas UK
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A Novel CFD Model of SMX Static Mixer Used in Advanced Continuous Manufacturing of Active Pharmaceutical Ingredients (API) J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-23 Athanasios Kritikos, Ravendra Singh, George Tsilomelekis, Fernando J. Muzzio
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Fluconazole Microsponges Loaded Bioadhesive Vaginal Film to Treat Vulvovaginal Candidiasiss J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-05 Priti L. Mandlik, Palakshi R. Lad, Ashlesha P. Pandit
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Design and Development of Immediate Release Pellets Formulation Containing Co Amorphous Mixture of Aceclofenac: In-Vitro and In-Vivo Study J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-05 Nahid Anjum Hafizuddin Chishti, Inayat Bashir Pathan, Mohamed Hassan G. Dehghan, Shripad M. Bairagi
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Assessment of Imaging Flow Cytometry for the Simultaneous Discrimination of Protein Particles and Silicone Oil Droplets in Biologicals J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-01
Abstract Purpose Silicone oil droplets in biopharmaceutical products can originate from sources such as siliconized surfaces of primary packaging materials, potentially triggering the formation of protein–silicone oil particles. To better understand this phenomenon, there is a need for particle detection devices that cannot only distinguish between protein particles and silicone oil droplets but also
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Integrated Continuous Process Design for Crystallisation, Spherical Agglomeration, and Filtration of Lovastatin J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-01 Cameron J. Brown, John McGinty, Muhammad T. Islam, Nazer Rajoub, Omid Arjmandi-Tash, Sara Ottoboni, Muhid Shahid, Stephanie J. Urwin, Ye Seol Lee, Magdalene W. S. Chong, Foteini Papathanasiou, Aruna S. Prakash, Elke Prasad, Bronwyn Spence, Jan Sefcik, John Robertson, Rachel Smith, James D. Litster, Chris J. Price, Alison Nordon, Claire S. Adjiman, Alastair J. Florence
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An Understanding of the Relationship Between Mixing Performance and Power Consumption in a High-Shear Wet Granulation Pre-mixing J. Pharm. Innov. (IF 2.6) Pub Date : 2024-03-01
Abstract Introduction High-shear wet granulation (HSWG) is most commonly used in the pharmaceutical industry, with the advantages of being fully enclosed, having a good mixing effect, and being highly efficient. However, only a few studies are geared toward an in-depth understanding of the pre-mixing process in the high-shear wet granulator (HSWGr). Objectives In this paper, the effect of impeller
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Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization J. Pharm. Innov. (IF 2.6) Pub Date : 2024-02-24 Nazneen Sultana, Divya Chauhan, Pavan K. Yadav, Manish K. Chourasia, Jiaur R. Gayen
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Repurposing of IL 33/ST2 Modulating Drugs as a Cardioprotective Agent: A Promising Approach J. Pharm. Innov. (IF 2.6) Pub Date : 2024-02-20 Punniyakoti Veeraveedu Thanikachalam, Srinivasan Ramamurthy, Prasanna Bharathi Sainath, Bharathi Radhakrishnan
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Development and Evaluation of Novel Amoxicillin and Phytic Acid-Loaded Gastro-Retentive Mucoadhesive Pectin Microparticles for the Management of Helicobacter pylori Infections J. Pharm. Innov. (IF 2.6) Pub Date : 2024-02-17
Abstract Purpose Amoxicillin, a treatment option widely employed against H. pylori infection, is becoming ineffective due to the rising antimicrobial resistance. The poor stability of amoxicillin in gastric juice, as well as amoxicillin resistance in H. pylori, has a negative impact on amoxicillin’s therapeutic efficacy. Because of its metal chelating capacity, phytic acid has been shown to improve
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Development and Characterization of Glimepiride-Loaded Polymeric Nanoparticles: Formulation Design and Evaluation J. Pharm. Innov. (IF 2.6) Pub Date : 2024-01-20 Zaiba Irfan, Muhammad Imran Khan, Muhammad Farhan Sohail, Muhammad Furqan Akhtar, Muhammad Naeem Qaisar, Muhammad Kashif Javed, Fareeha Anwar, Badarqa-tul-Ayesha, Majid Anwar, Aslam Khan, Faizan Akram
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Effect of Rosa damascena Essential Oil Loaded in Nanostructured Lipid Carriers on the Proliferation of Human Breast Cancer Cell Line MDA-MB-231 in Comparison with Cisplatin J. Pharm. Innov. (IF 2.6) Pub Date : 2024-01-19 Elham Yari, Soyar Sari, Hamidreza Kelidari, Kofi Asare-Addo, Ali Nokhodchi
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Surface Engineering and Optimizing DepoFoam System: A Robust Quality by Design Approach for Optimal Drug Delivery, Stability, and Quality J. Pharm. Innov. (IF 2.6) Pub Date : 2024-01-18 Jebastin Koilpillai, Damodharan Narayanasamy
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Formulation and Characterization of Interpenetrating Polymer Network Hydrogel Bead as Drug Carrier System for Extended Release of Sulphonyl Urea Medication J. Pharm. Innov. (IF 2.6) Pub Date : 2024-01-17 Kalaiarasan Sellamuthu, Sheela Angappan
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Preparation and Physicochemical Characterizations of Niosomal Benzoyl Peroxide and Clindamycin Phosphate Formulation for Acne Vulgaris J. Pharm. Innov. (IF 2.6) Pub Date : 2024-01-11 Maryam Rezaeizadeh, Amir Eskanlou, Abbas Pardakhty, Mostafa Pournamdari, Mohammad Daneshpajooh
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Formulation, Characterization, and Optimization of Transethosomes for Enhanced Transdermal Delivery of Methotrexate J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-27 Priyanka J. Veer, Vinayak S. Mastiholimath
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Enhancing the Dissolution of Flutamide Through Supersaturation Using Beta-Cyclodextrin: a Promising Approach for Improved Solubility of Poorly Water-Soluble Drugs J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-22 Shaghayegh Hoseini Aghdam, Saeideh Allahyari
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Elucidation of Tartaric Acid-Assisted Supersaturation Maintenance of Dipyridamole by Eudragit® E100 J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-16 Maryam Maghsoodi, Vahid Baghcheh, Mohammad Feyzizadeh, Ashkan Barfar, Ali Nokhodchi
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Coloaded Surface–Modified PLGA Nanoparticles for Sustained Ocular Delivery of Levofloxacin and Flurbiprofen J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-12 Ujwala Shinde, Yusra Barkat, Kavita Singh
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A Systems Evaluation Model for the Development of Companion Diagnostics and Associated Molecularly Targeted Therapies J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-11 Kozue Okamura, Hiroki Tsuchiya, Risa Hamada, Yusuke Hayashi, Sara Badr, Seiichi Ohta, Hirokazu Sugiyama
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Loss-on-Drying Prediction for a Vibrated Fluidised Bed Dryer by Means of Mass and Energy Balances J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-08 Katharina Kiricenko, Felix Hartmann, Andreas Altmeyer, Peter Kleinebudde
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pH-Triggered Dynamic Carrier-Free Nanodrugs Self-Assembled from Dasatinib and Chlorambucil with a Potential for Precise Tumoral Targeting Theranostic J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-30 Yuanpeng Wang, Chensong Zhang, Shaobo Zhou, Liang Chu, Wei Fang, Jiachi Ma
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Exploring Liposomal Systems for Gallic Acid and Tannic Acid Delivery: Potential Strategies to Address Inflammation and Infections in Pediatric Ventricular Assist Device Recipients J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-04 Yongjun Ma, Lanlan Guo, Jionghuan Ying, Yanyan Xu
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Topical Delivery of Methoxsalen Co-loaded Curcumin Using Hybrid Nanocarrier-Based Polymeric Hydrogel for Synergistic Therapy in the Treatment of Psoriasis J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-05 Taison Jamatia, Sanjoy Das, Malay K Das
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Optimization, Formulation, and Stability of Topical Rapamycin Used for Rare Tuberous Sclerosis Disease: from Ointment to Liposomes J. Pharm. Innov. (IF 2.6) Pub Date : 2023-12-05 Clara Cortell-Fuster, María Amparo Martínez-Gómez, Ana Cristina Cercós-Lleti, Mónica Climente-Martí
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Exploiting response surface D-optimal design study for preparation and optimization of spanlastics loaded with miconazole nitrate as a model antifungal drug for topical application J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-30 Mervat Shafik Ibrahim, Omar A. Elkady, Mai A. Amer, Shereen H. Noshi
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Formulation and Characterization of Luliconazole Microsponge Gel for Diaper Dermatitis J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-30 Pavithra Bharathy, Punniyakoti V. Thanikachalam, Nithya Priya Parthasarathy, Pavithra Elumalai, Pavithra Krishnamoorthy Baskaran, Thameemul Ansari L. H.
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Study on the Correlation Between Nimodipine (BCS Class II) Solubility, Dissolution Improvement, and Brain Tissue Concentration Through Cocrystallization J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-26 Nilam Rathod, Chetan Borkhataria, Ravi Manek, Vidhi Patel, Nilesh Patel, Kalpesh Patel, Jalpa Paun, Dhruv Sakhiya
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QBD Approach for Design and Characterization of Pramlintide Microspheres for Controlled Drug Release J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-23 Lakshmikanth Reddy P, Sangeetha Shanmugasundaram
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Mechanism Changes with High Temperature: Significance for Use of Accelerated Aging Modeling of Pharmaceuticals J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-21 Kenneth C. Waterman
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QbD-Driven Development and Characterization of Solid Lipid Nanoparticles (SLNs)–Based Nanogel of Luliconazole for the Effective Management of Dermal Fungal Infection J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-15 Gaurav Khurana, Vir Vikram Sharma, Daisy Arora
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Synthesis and Characterization of Cosmetic Grade Ionic Liquids and Their Application as Skin Whitening Agents J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-14 Farah Bashir, Nawshad Muhammad, Meshal Alshamrani, Maliha Uroos, Ahmad Salawi, Awaji Y. Safhi, Naveed Ahmed, Abdullah Alsalhi, Fahad Y. Sabei, Osama A. Madkhali
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SGLT-2i: Nanoparticular-Based Strategies, Solutions, and Clinical Applications in Opposition to Low Bioavailability J. Pharm. Innov. (IF 2.6) Pub Date : 2023-11-09 Burcu Yesildag Uner, Osman Yesildag
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Development, Optimization, and Evaluation of Nano-platforms for Delivery of siRNA and BPTES in c-Myc Induced Breast Cancer J. Pharm. Innov. (IF 2.6) Pub Date : 2023-10-31 Arpita Paul, Avirup Biswas, Swarnabh Chatterjee, Alan Raj, Ruchira Raychaudhuri, Srinivas Mutalik, Angel Treasa Alex
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Development, Characterization, and Ex Vivo Permeation Assessment of Diclofenac Diethylamine Deep Eutectic Systems Across Human Skin J. Pharm. Innov. (IF 2.6) Pub Date : 2023-10-28 Layaly Al-Mawla, Faisal Al-Akayleh, Saifeddin Daadoue, Waseem Mahyoob, Badralbdoor Al-Tameemi, Mayyas Al-Remawi, Samer Adwan, Ahmed S. A. Ali Agha
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Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin Calcium by Solid Dispersion Technique Using a Modified Natural Polymer as a Hydrophilic Carrier J. Pharm. Innov. (IF 2.6) Pub Date : 2023-10-21 Avinash R. Tekade, Sneha U. Mathapati, Mukesh P. Ratnaparkhi, Gajanan M. Kulkarni
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Effect of Manufacturing Conditions on Particle Characteristics in the Drug-Layering Process of a Novel Melt Granulation Technology, MALCORE®, Using a Design of Experiments J. Pharm. Innov. (IF 2.6) Pub Date : 2023-10-20 Naoki Yoshihara, Ryota Kimata, Takayuki Terukina, Hiromu Kondo
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Fabrication and Evaluation of Differential Release Bilayer Tablets of Clarithromycin and Levofloxacin by 3D Printing J. Pharm. Innov. (IF 2.6) Pub Date : 2023-10-06 Qazi Amir Ijaz, Sumera Latif, Sumaira Irum Khan, Memoona Rashid, Hafsa Afzal, Nasrullah Jan, Zeeshan Javaid, Muhammad Sarfraz, Amjad Hussain, Muhammad Sohail Arshad, Nadeem Irfan Bukhari, Nasir Abbas
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Development and Evaluation of Fucoidan-Based Liposomes: Targeting Smooth Muscle Cells for Atherosclerosis Treatment J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-27 Likai Han, Lili Yu
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Curcumin-Loaded Chitosan-Coated 5-Fluorouracil Encapsulated Nanozeolitic Imidazolate Framework for Combination Cancer Therapy J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-19 Jiju Kazhani Radhakrishnan, Subhadra Suma, Anoop Somasekharan Nair, Reshmi Ramachandran
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Silver Nanoparticle Synthesized with Fenugreek Leaves Is Biologically Potent than Chemically Synthesized Nanoparticle J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-10 Kunal Kishore, Pooja Prasad, Nandakumar Selvasudha, Saranga Rajesh, Hannah R. Vasanthi
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Quality by Design Approach for Optimization of 5-Fluorouracil Microbeads Using Box–Behnken Design and Desirability Function for Colon Targeting J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-04 Amit Kumar Pandey, Udaivir Singh Sara
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QBD Approach for the Design, Optimization, Development, and Characterization of Naringenin-Loaded Phytosomes to Enhance Solubility and Oral Bioavailability J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-02 Vijay Metkari, Rohit Shah, Nitin Salunkhe, Shailendra Gurav
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Esomeprazole-Loaded Flash Release Sublingual Wafers: Formulation, Optimization, and Characterization J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-02 Krutuja Chougule, Panchaxari M. Dandagi, Sujay Hulyalkar
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Mucoadhesive (Type-I) and Floating (Type-II) Chitosan Beads for Improved Gastric Retention of Clarithromycin J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-02 Habib Ur Rehman, Muhammad Danish Saeed, Faqir Ullah, Faiqa Falak Naz, Kamran Ahmad Khan, Kifayat Ullah Shah
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Effect of Liquid Paraffin on the Characteristics of Pressure-Sensitive Adhesives Applied to Medical Tape Formulations J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-31 Takayuki Terukina, Saori Muramoto, Kaede Osanai, Miho Inoue, Hirotaka Watanabe, Yuki Hakamata, Haruhiko Hikichi, Hiromu Kondo
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Design of Dual Principles Floating Osmotic Drug Delivery System of Pioglitazone Hydrochloride for Gastro-retention: In Vitro-In Vivo Evaluation J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-01 Pankaj Dangre, Navnath Gundre, Satish Meshram, Dilip Madia, Mangesh Godbole
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Does Firm’s Alliances Increase New Drug Development Time? A Multiple Regression Analysis of Clinical Development Time J. Pharm. Innov. (IF 2.6) Pub Date : 2023-09-01 Ho-Kyoung Kim, Hyesung Lee, Sang-Won Lee
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Fabrication of a Dual-Triggered Natural Gum–Based Multi-Particulate Colon-Targeted Drug Delivery System of Budesonide Using the QbD Approach J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-29 Jaymin Patel, Kaushika Patel, Shreeraj Shah
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A Novel Azathioprine Polysaccharide Nanoparticle Enhances the Efficacy of Systemic Lupus Erythematosus Therapy J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-28 Chandrababu Rejeeth, Nipun Babu Varukattu, Alok Sharma, Raju Suresh Kumar, Abdulrahman I. Almansour, Natarajan Arumugam
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A Potential Breakthrough in the Enhancement of Glimepiride Solubility and Dissolution Rate by Binary and Ternary Solid Dispersion Technique and In Vitro Comparison with Marketed Formulation J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-25 Rideb Chakraborty, Naureen Afrose, Ketousetuo Kuotsu
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Formulation, Development, and Comparative Study of Azelastine-Loaded Temperature Sensitive In Situ Gelling Micelles for Allergic Conjunctivitis J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-18 Vinayak Ranade, Yashodhara Dalal, Hirachand Y Palampalle, Kavita Singh
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Similar but Not Same: Impact of Structurally Similar Coformers on Co-crystallization with Telmisartan J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-16 Arun Kumar, Arun Nanda
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Development of Fluoride-Loaded Chitosan Microparticles for Controlled Drug Delivery: A Comparative Study of PVP K17 and Eudragit® RS 30D as Coating Polymer J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-15 Federico A. Fookes, Natalia S. Velázquez, Alfredo Rigalli, Julio A. Luna
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Carvedilol-Loaded Cubosome Gel to Accelerate Wound Healing J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-12 Ashlesha P. Pandit, Vinit S. Kulkarni, Vaishali M. Mute, Ujjwala Y. Kandekar
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Formulation Development of Dual Drug-Loaded Thermosensitive Ocular In Situ Gel Using Factorial Design J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-10 Heybet Kerem Polat, Aslıhan Arslan, Sedat Ünal, Muhammet Kerim Haydar, Eren Aytekin, Sefa Gözcü, Nasıf Fatih Karakuyu, Behzad Mokhtare
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Design, Development, and In Vitro Characterization of Pirfenidone-Loaded Biodegradable Nanoparticles for Idiopathic Pulmonary Fibrosis J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-07 Kiran R. Dudhat, Harsha V. Patel, Dhaval D. Mori
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The Development of Digital Therapies as a New Therapeutic Option to Treat Diseases: Focus on the International Regulatory Framework J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-07 Alessia Romagnoli, Filomena Valentino, Andrea Zovi, Andrea Caprodossi, Antonio Vitiello, Francesco Ferrara
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Utilizing Quality by Design to Develop and Evaluate Extended-Release Upadacitinib Tablets Incorporating a Biosynthesized Polymer J. Pharm. Innov. (IF 2.6) Pub Date : 2023-08-01 K. Sunil Chowdary, A. A. Napoleon