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Compounds from Agathis dammara exert hypoglycaemic activity by enhancing glucose uptake: lignans, terpenes and others Nat. Prod. Bioprospect. Pub Date : 2024-03-22 Zhe-Wei Yu, Bang-Ping Cai, Su-Zhi Xie, Yi Zhang, Wen-Hui Wang, Shun-Zhi Liu, Yan-Lin Bin, Qi Chen, Mei-Juan Fang, Rong Qi, Ming-Yu Li, Ying-Kun Qiu
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Gastrodinol derivatives and prenylated flavones from the flower branch of Gastrodia elata Nat. Prod. Bioprospect. Pub Date : 2024-03-20 Shi-Hui Qin, Zhi-Lan Li, Liu Yang, Jiang-Miao Hu
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Which is the optimal choice for neonates’ formula or breast milk? Nat. Prod. Bioprospect. Pub Date : 2024-03-15 Yueqi Hu, Xing Wu, Li Zhou, Jikai Liu
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Current advances on the therapeutic potential of scutellarin: an updated review Nat. Prod. Bioprospect. Pub Date : 2024-03-04 Yifei Xie, Guotong Sun, Yue Tao, Wen Zhang, Shiying Yang, Li Zhang, Yang Lu, Guanhua Du
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3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation Nat. Prod. Bioprospect. Pub Date : 2024-03-04 Li-Jun Ruan, Zhi-Jun Song, Ren-Wang Jiang
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Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin Nat. Prod. Bioprospect. Pub Date : 2024-02-29 Guifeng Su, Dan Wang, Qianqing Yang, Lingmei Kong, Xiaoman Ju, Qihong Yang, Yiying Zhu, Shaohua Zhang, Yan Li
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Libertellenone C attenuates oxidative stress and neuroinflammation with the capacity of NLRP3 inhibition Nat. Prod. Bioprospect. Pub Date : 2024-02-26 Jie Cao, Lanqin Li, Runge Zhang, Zhou Shu, Yaxin Zhang, Weiguang Sun, Yonghui Zhang, Zhengxi Hu
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Petrosamine isolated from marine sponge Petrosia sp. demonstrates protection against neurotoxicity in vitro and in vivo Nat. Prod. Bioprospect. Pub Date : 2024-02-22 Joana Ribeiro, Henrique Araújo-Silva, Mário Fernandes, Joilna Alves da Silva, Francisco das Chagas L. Pinto, Otília Deusdenia L. Pessoa, Hélcio Silva Santos, Jane Eire Silva Alencar de Menezes, Andreia C. Gomes
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Characterization of Chilean hot spring-origin Staphylococcus sp. BSP3 produced exopolysaccharide as biological additive Nat. Prod. Bioprospect. Pub Date : 2024-02-04 Srijan Banerjee, Gustavo Cabrera-Barjas, Jaime Tapia, João Paulo Fabi, Cedric Delattre, Aparna Banerjee
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Chemistry and biology of marine-derived Trichoderma metabolites Nat. Prod. Bioprospect. Pub Date : 2024-02-02
Abstract Marine-derived fungi of the genus Trichoderma have been surveyed for pharmaceuticals and agrochemicals since 1993, with various new secondary metabolites being characterized from the strains of marine animal, plant, sediment, and water origin. Chemical structures and biological activities of these metabolites are comprehensively reviewed herein up to the end of 2022 (covering 30 years). More
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Natural and engineered xylosyl products from microbial source Nat. Prod. Bioprospect. Pub Date : 2024-02-01 Jianzhao Qi, Shi-jie Kang, Ling Zhao, Jin‑ming Gao, Chengwei Liu
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The contemporary nexus of medicines security and bioprospecting: a future perspective for prioritizing the patient Nat. Prod. Bioprospect. Pub Date : 2024-01-25 Geoffrey A. Cordell
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Interaction mechanism between luteoloside and corn silk glycans and the synergistic role in hypoglycemic activity Nat. Prod. Bioprospect. Pub Date : 2024-01-16 Shihui Qin, Yanlang Li, Huiyan Shao, Yang Yu, Yina Yang, Yi Zeng, Jia Huang, Jiang-miao Hu, Liu Yang
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Neuroprotective properties of exosomes and chitosan nanoparticles of Tomafran, a bioengineered tomato enriched in crocins Nat. Prod. Bioprospect. Pub Date : 2024-01-12 Mikel Etxebeste-Mitxeltorena, Enrique Niza, Cristián Martinez Fajardo, Carmen Gil, Lourdes Gómez-Gómez, Ana Martinez, Oussama Ahrazem
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Koningipyridines A and B, two nitrogen-containing polyketides from the fungus Trichoderma koningiopsis SC-5 Nat. Prod. Bioprospect. Pub Date : 2024-01-11
Abstract Two novel koninginin derivatives, koningipyridines A and B (1 and 2), along with four known compounds (3˗6) were isolated from the EtOAc extract of the endophytic fungus Trichoderma koningiopsis SC-5. Among them, koningipyridine A featured an unprecedented pentacyclic ketal skeleton with the formation of a fascinating 6/6/5/6/5 fused ring system and shared a characteristic pyridine core, which
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Precision enzyme discovery through targeted mining of metagenomic data Nat. Prod. Bioprospect. Pub Date : 2024-01-11 Shohreh Ariaeenejad, Javad Gharechahi, Mehdi Foroozandeh Shahraki, Fereshteh Fallah Atanaki, Jian-Lin Han, Xue-Zhi Ding, Falk Hildebrand, Mohammad Bahram, Kaveh Kavousi, Ghasem Hosseini Salekdeh
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Eco-friendly approaches to phytochemical production: elicitation and beyond Nat. Prod. Bioprospect. Pub Date : 2024-01-10
Abstract Highly ameliorated phytochemicals from plants are recognized to have numerous beneficial effects on human health. However, obtaining secondary metabolites directly from wild plants is posing a great threat to endangered plant species due to their over exploitation. Moreover, due to complicated structure and stereospecificity chemical synthesis of these compounds is a troublesome procedure
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Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies Nat. Prod. Bioprospect. Pub Date : 2024-01-08
Abstract Diabetes mellitus remains a major global health issue, and great attention is directed at natural therapeutics. This systematic review aimed to assess the potential of flavonoids as antidiabetic agents by investigating their inhibitory effects on α-glucosidase and α-amylase, two key enzymes involved in starch digestion. Six scientific databases (PubMed, Virtual Health Library, EMBASE, SCOPUS
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Antiproliferative polyketides from fungus Xylaria cf. Longipes SWUF08-81 in different culture media Nat. Prod. Bioprospect. Pub Date : 2024-01-06 Kittiwan Sresuksai, Sasiphimol Sawadsitang, Phongphan Jantaharn, Pakin Noppawan, Audomsak Churat, Nuttika Suwannasai, Wiyada Mongkolthanaruk, Thanaset Senawong, Sarawut Tontapha, Pairot Moontragoon, Vittaya Amornkitbamrung, Sirirath McCloskey
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Modulation of mitochondrial activity by sugarcane (Saccharum officinarum L.) top extract and its bioactive polyphenols: a comprehensive transcriptomics analysis in C2C12 myotubes and HepG2 hepatocytes Nat. Prod. Bioprospect. Pub Date : 2024-01-05 Kengo Iwata, Farhana Ferdousi, Yoshinobu Arai, Hiroko Isoda
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β-carboline derivative Z86 attenuates colorectal cancer cell proliferation and migration by directly targeting PI3K Nat. Prod. Bioprospect. Pub Date : 2024-01-03 Shiyun Nie, Lizhong Chang, Ying Huang, Heyang Zhou, Qianqing Yang, Lingmei Kong, Yan Li
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Disclosing the potential of Cupressus leylandii A.B. Jacks & Dallim, Eucalyptus globulus Labill., Aloysia citrodora Paláu, and Melissa officinalis L. hydrosols as eco-friendly antimicrobial agents Nat. Prod. Bioprospect. Pub Date : 2024-01-02 Heloísa H. S. Almeida, Pedro J. L. Crugeira, Joana S. Amaral, Alírio E. Rodrigues, Maria-Filomena Barreiro
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Kaemtakols A–D, highly oxidized pimarane diterpenoids with potent anti-inflammatory activity from Kaempferia takensis Nat. Prod. Bioprospect. Pub Date : 2023-12-01 Orawan Jongsomjainuk, Jutatip Boonsombat, Sanit Thongnest, Hunsa Prawat, Paratchata Batsomboon, Sitthivut Charoensutthivarakul, Saroj Ruchisansakun, Kittipong Chainok, Jitnapa Sirirak, Chulabhorn Mahidol, Somsak Ruchirawat
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A comprehensive review on the chemical constituents, sesquiterpenoid biosynthesis and biological activities of Sarcandra glabra Nat. Prod. Bioprospect. Pub Date : 2023-11-27 Jin-Ning Chu, Premanand Krishnan, Kuan-Hon Lim
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Quinones from Cordia species from 1972 to 2023: isolation, structural diversity and pharmacological activities Nat. Prod. Bioprospect. Pub Date : 2023-11-24 Rostanie Dongmo Zeukang, Jarmo-Charles Kalinski, Babalwa Tembeni, Eleonora D. Goosen, Jacqueline Tembu, Turibio Tabopda Kuiate, Dominique Serge Ngono Bikobo, Maurice Tagatsing Fotsing, Alex de Théodore Atchadé, Xavier Siwe-Noundou
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A recent update on development, synthesis methods, properties and application of natural products derived carbon dots Nat. Prod. Bioprospect. Pub Date : 2023-11-13 Soumitra Sahana, Anupam Gautam, Rajveer Singh, Shivani Chandel
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Ginsenoside compound-K attenuates OVX-induced osteoporosis via the suppression of RANKL-induced osteoclastogenesis and oxidative stress Nat. Prod. Bioprospect. Pub Date : 2023-11-09 Lingli Ding, Zhao Gao, Siluo Wu, Chen Chen, Yamei Liu, Min Wang, Yage Zhang, Ling Li, Hong Zou, Guoping Zhao, Shengnan Qin, Liangliang Xu
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The alkynyl-containing compounds from mushrooms and their biological activities Nat. Prod. Bioprospect. Pub Date : 2023-11-10 Ji-shuang Qi, Yingce Duan, Zhao-chen Li, Jin-ming Gao, Jianzhao Qi, Chengwei Liu
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l-Palmitoylcarnitine potentiates plasmin and tPA to inhibit thrombosis Nat. Prod. Bioprospect. Pub Date : 2023-11-08 Juan Yang, Lina Cha, Yepeng Wang, Quan Zhang, Xiaopeng Tang, Jianlin Shao, Zilei Duan
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Occurrence of D-amino acids in natural products Nat. Prod. Bioprospect. Pub Date : 2023-11-07 Daniel W. Armstrong, Alain Berthod
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Three previously undescribed metabolites from Cordyceps cicadae JXCH-1, an entomopathogenic fungus Nat. Prod. Bioprospect. Pub Date : 2023-11-03 Jing Fan, Pai Liu, Kuan Zhao, He-Ping Chen
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Bioactive molecules from terrestrial and seafood resources in hypertension treatment: focus on molecular mechanisms and targeted therapies Nat. Prod. Bioprospect. Pub Date : 2023-10-30 Md. Rezaul Islam, Puja Sutro Dhar, Shopnil Akash, Sabeena Hussain Syed, Jeetendra Kumar Gupta, Kumaraswamy Gandla, Muniya Akter, Abdur Rauf, Hassan A. Hemeg, Yasir Anwar, Bassam Oudh Aljohny, Polrat Wilairatana
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Untargeted metabolomics analysis of four date palm (Phoenix dactylifera L.) cultivars using MS and NMR Nat. Prod. Bioprospect. Pub Date : 2023-10-23 Shuruq Alsuhaymi, Upendra Singh, Inas Al-Younis, Najeh M. Kharbatia, Ali Haneef, Kousik Chandra, Manel Dhahri, Mohammed A. Assiri, Abdul-Hamid Emwas, Mariusz Jaremko
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The antifungal properties of terpenoids from the endophytic fungus Bipolaris eleusines Nat. Prod. Bioprospect. Pub Date : 2023-10-23 Yin-Zhong Fan, Chun Tian, Shun-Yao Tong, Qing Liu, Fan Xu, Bao-Bao Shi, Hong-Lian Ai, Ji-Kai Liu
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Biological activities of gastropods secretions: snail and slug slime Nat. Prod. Bioprospect. Pub Date : 2023-10-23 Muhammad Rashad, Simone Sampò, Amelia Cataldi, Susi Zara
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Cytotoxic phenazine and antiallergic phenoxazine alkaloids from an arctic Nocardiopsis dassonvillei SCSIO 502F Nat. Prod. Bioprospect. Pub Date : 2023-10-18 Yue Song, Qi-Yang Li, Meng-Jing Cong, Xiao-Yan Pang, Bo Chen, Yong-Hong Liu, Li Liao, Jun-Feng Wang
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The role of sound stimulation in production of plant secondary metabolites Nat. Prod. Bioprospect. Pub Date : 2023-10-17 Li Wu, Ning Yang, Meng Guo, Didi Zhang, Reza A. Ghiladi, Hasan Bayram, Jun Wang
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Exploring the role of natural bioactive molecules in genitourinary cancers: how far has research progressed? Nat. Prod. Bioprospect. Pub Date : 2023-10-16 Fahadul Islam, Nikhil Nath, Mehrukh Zehravi, Jishan Khan, Sumiya Ben-Ta Jashim, Manoj Shrawan Charde, Rita Dadarao Chakole, K. Praveen Kumar, A. Kishore Babu, Firzan Nainu, Sharuk L. Khan, Safia Obaidur Rab, Talha Bin Emran, Polrat Wilairatana
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Indonesian marine and its medicinal contribution Nat. Prod. Bioprospect. Pub Date : 2023-10-16 Ari Satia Nugraha, Lilla Nur Firli, Dinar Mutia Rani, Ayunda Hidayatiningsih, Nadya Dini Lestari, Hendris Wongso, Kustiariyah Tarman, Ayu Christien Rahaweman, Jeprianto Manurung, Ni Putu Ariantari, Adelfia Papu, Masteria Yunovilsa Putra, Antonius Nugraha Widhi Pratama, Ludger A. Wessjohann, Paul A. Keller
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Prioritised identification of structural classes of natural products from higher plants in the expedition of antimalarial drug discovery Nat. Prod. Bioprospect. Pub Date : 2023-10-12 Phanankosi Moyo, Luke Invernizzi, Sephora M. Mianda, Wiehan Rudolph, Andrew W. Andayi, Mingxun Wang, Neil R. Crouch, Vinesh J. Maharaj
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Essential oil extracted from Quzhou Aurantii Fructus prevents acute liver failure through inhibiting lipopolysaccharide-mediated inflammatory response Nat. Prod. Bioprospect. Pub Date : 2023-10-07 Tian Lan, Wen Wang, De-Lian Huang, Xi-Xi Zeng, Xiao-Xiao Wang, Jian Wang, Yu-Hua Tong, Zhu-Jun Mao, Si-Wei Wang
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Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery Nat. Prod. Bioprospect. Pub Date : 2023-10-05 Phanankosi Moyo, Luke Invernizzi, Sephora M. Mianda, Wiehan Rudolph, Warren A. Andayi, Mingxun Wang, Neil R. Crouch, Vinesh J. Maharaj
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Anxiolytic-like effects of Pseudospondias microcarpa hydroethanolic leaf extract in zebrafish: Possible involvement of GABAergic and serotonergic pathways Nat. Prod. Bioprospect. Pub Date : 2023-10-04 Donatus Wewura Adongo, Charles Kwaku Benneh, Augustine Tandoh, Robert Peter Biney, Kennedy Kwami Edem Kukuia, Priscilla Kolibea Mante, Benjamin Kingsley Harley, David Oteng, Emmanuel Aduboffour Appiah, Ernest Cudjoe Anorbor, Eric Woode
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Marine natural product lepadin A as a novel inducer of immunogenic cell death via CD91-dependent pathway Nat. Prod. Bioprospect. Pub Date : 2023-10-02 Dalila Carbone, Carmela Gallo, Genoveffa Nuzzo, Giusi Barra, Mario Dell’Isola, Mario Affuso, Olimpia Follero, Federica Albiani, Clementina Sansone, Emiliano Manzo, Giuliana d’Ippolito, Angelo Fontana
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Bioactivity profile of dissolved organic matter and its relation to molecular composition Nat. Prod. Bioprospect. Pub Date : 2023-09-18 Teresa S. Catalá, Linn G. Speidel, Arlette Wenzel-Storjohann, Thorsten Dittmar, Deniz Tasdemir
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Andropanilides A-C, the novel labdane-type diterpenoids from Andrographis paniculata and their anti-inflammation activity Nat. Prod. Bioprospect. Pub Date : 2023-09-15 Yang Yu, Yang Wang, Gui-Chun Wang, Cheng-Yong Tan, Yi Wang, Jin-Song Liu, Guo-Kai Wang
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Optimized solubility and bioavailability of genistein based on cocrystal engineering Nat. Prod. Bioprospect. Pub Date : 2023-09-13 Zhipeng Wang, Qi Li, Qi An, Lixiang Gong, Shiying Yang, Baoxi Zhang, Bin Su, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du
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Three new amide derivatives from the fungus Alternaria brassicicola Nat. Prod. Bioprospect. Pub Date : 2023-09-11 Fengli Li, Saisai Gu, Sitian Zhang, Shuyuan Mo, Jieru Guo, Zhengxi Hu, Yonghui Zhang
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Puerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier Nat. Prod. Bioprospect. Pub Date : 2023-09-12 Qing Tao, Jinhua Zhang, Qiao liang, Shiyu Song, Shuxia Wang, Xiaoming Yao, Qian Gao, Lei Wang
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Narciclasine, a novel topoisomerase I inhibitor, exhibited potent anti-cancer activity against cancer cells Nat. Prod. Bioprospect. Pub Date : 2023-08-29 Meichen Wang, Leilei Liang, Rong Wang, Shutao Jia, Chang Xu, Yuting Wang, Min Luo, Qiqi Lin, Min Yang, Hongyu Zhou, Dandan Liu, Chen Qing
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Two pyrrole acids isolated from Phyllanthus emblica L. and their bioactivities Nat. Prod. Bioprospect. Pub Date : 2023-08-28 Shu-Hui Wang, Cong Guo, Wen-Jin Cui, Qing-Xia Xu, Jun Zhang, Jin-Zhu Jiang, Yan Liu, Sha Chen, Chang Chen, Jin-Tang Cheng, An Liu
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Quality assurance of postharvest grapes against Botrytis cinerea by terbinafine Nat. Prod. Bioprospect. Pub Date : 2023-08-18 Yun Zhao, Qiong Jin, Zi-Jiao Wang, Xing-Yu Tao, Xiao-Dong Luo
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Unleashing the potential: further enhancing the impact of Natural Products and Bioprospecting. Nat. Prod. Bioprospect. Pub Date : 2023-08-17 Ji-Kai Liu,Xiao-Dong Luo,Ling Zhang,Ying Zhang
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Terpenes extracted from marine sponges with antioxidant activity: a systematic review Nat. Prod. Bioprospect. Pub Date : 2023-08-09 Cintia Cristina Santi Martignago, Beatriz Soares-Silva, Julia Risso Parisi, Lais Caroline Souza e Silva, Renata Neves Granito, Alessandra Mussi Ribeiro, Ana Cláudia Muniz Renno, Lorena Ramos Freitas de Sousa, Anna Caroline Campos Aguiar
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Four undescribed pyrethrins from seeds of Pyrethrum cinerariifolium and their aphidicidal activity Nat. Prod. Bioprospect. Pub Date : 2023-07-07 Hao-Ran Zhou, Li-Wu Lin, Zhong-Rong Li, Xing-Rong Peng, Ming-Hua Qiu
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New halimane and clerodane diterpenoids from Croton cnidophyllus Nat. Prod. Bioprospect. Pub Date : 2023-07-06 Xun Wei, Jia-Luo Huang, Hua-Hua Gao, Fang-Yu Yuan, Gui-Hua Tang, Sheng Yin
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Therapeutic effects of isoquercetin on ovariectomy-induced osteoporosis in mice Nat. Prod. Bioprospect. Pub Date : 2023-06-08 Mengjing Wu, Mengyu Qin, Xian Wang
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Effects of combined cannabidiol (CBD) and hops (Humulus lupulus) terpene extract treatment on RAW 264.7 macrophage viability and inflammatory markers Nat. Prod. Bioprospect. Pub Date : 2023-06-07 Inga Dammann, Claudia Keil, Iris Hardewig, Elżbieta Skrzydlewska, Michał Biernacki, Hajo Haase
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Structural characterizations and α-glucosidase inhibitory activities of four Lepidium meyenii polysaccharides with different molecular weights Nat. Prod. Bioprospect. Pub Date : 2023-06-06 Luan Wen, Zhou-Wei Wu, Li-Wu Lin, Abdulbaset Al-Romaima, Xing-Rong Peng, Ming-Hua Qiu