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In Vitro Antioxidant Activity of Asteriscus Graveolens (Forsk.) and Its Protective Effect on Doxorubicin-Induced Hepatotoxicity and Testicular Oxidative Damage in Rats Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-18 Amira Mecheri, Leila Hammoud, Samia Belahcene, Nassima Boubekri, Mounir Kout, Fadila Benayache, Amel Amrani
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Stereospecificity of the Cytoprotective and Antidepressant-Like Activities of GTS-301, a Dimeric Dipeptide Mimetic of Neurotrophin-3 Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-18 N. M. Sazonova, A. V. Tarasiuk, M. V. Melnikova, I. A. Zhanataev, I. O. Logvinov, S. V. Nikolaev, D. M. Nikiforov, T. A. Antipova, P. Yu. Povarnina, T. A. Gudasheva, S. B. Seredenin
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Validation Studies of Some Stages of Drug Production from Equine Blood Plasma Regarding the Reduction of Extraneous Viruses Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 V. V. Mashin, A. N. Sergeev, N. N. Martynova, A. N. Galiullina, O. G. Yakin, A. Yu. Grosheva, T. I. Glotova, V. V. Kataeva, N. V. Zagidullin
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Utilization of Phytochemicals as Nutraceutical in the Prophylaxis of Dengue Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 Jyoti Baranwal, Swastika Singh, Smriti Kushwaha, Archana Jyoti
Every year, during the monsoon season, dengue, an infectious disease transmitted by the Aedes aegypti mosquito and caused by the dengue virus, occurs. The frequency and prevalence of dengue fever, as well as deaths from its consequences, have increased dramatically in recent years. Despite the fact that the infection has affected a large number of people worldwide, no specific and efficient drug treatment
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Isolation, Characterization of Bioactive Compounds from Muntingia calabura – a Pharmacological Study Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 Siddhartha Marupati, Shashikala Kethireddy, Laxminarayana Eppakayala
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Six Phthalides as Potent Modulators of the Blood Tumor Barrier Increase the Transmembrane Transport of Compatible Compounds Via Transcellular and Paracellular Pathways Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 Xiao-jin Liu, Shu-yuan Shuai, Guo-song Zhang, Qin Zheng, Peng-yi Hu, Zi-qi Li, Ri-qun Liu, Shu-hua Xiao
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Prospects of Creating Collagen Substances Based on a Study of the Physical and Chemical Characteristics of Proteins of Hydrobiont Dermal Emulsions Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 S. S. Antipov, D. V. Tarasova, M. M. Borodina, M. V. Likhodzievskaya, D. A. Cherenkov, T. N. Khmelevskaya, L. V. Antipova, V. G. Artyukhov
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Development of a Quantitative Determination Method for Polysorbate 80 in Biologicals by Size-Exclusion High-Performance Liquid Chromatography Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 O. B. Rounova, M. G. Korotkov, O. B. Ustinnikova
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Synthesis, Characterization and Biological Evaluation of Novel Benzimidazole Derivatives against Candida albicans Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 Monika Chauhan, Shivani Gupta, Sarvesh Paliwal, Sumitra Nain
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Chemical Composition and Antioxidant Activity of Petroleum Ether Extract from Kaempferia galanga L. Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 Zhaobao Xiang, Xueli Ping, Pengfei Chen, Linfeng You, Bin Zhou
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In-Vitro Effect of Ammodaucus Leucotrichus Flower and Fruit Essential Oils on Nitric Oxide Production and Arginase Activity in Human Peripheral Blood Mononuclear Cells (PBMC) from Patients with Behçet Disease Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 Djamel Messaoudene, Nourelhouda Ghozali, Hayet Neghliz, Tarek Benabdelkader, Houda Belguendouz, Malika Terahi, Fifi Otmani, Chafia Touil-Boukoffa
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Study of the Pressing Process of N-Butyl-N-Methyl-1-Phenylpyrrolo-[1,2-a]Pyrazine-3-Carboxamide (GML-3) Tablets Using Mathematical Modeling Techniques Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-17 V. B. Markeev, S. V. Tishkov, E. V. Blynskaya, K. V. Alekseev
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Mechanical Inclusions in Ophthalmic Drugs Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-16 O. V. Gunar, A. V. Dorenskaya, N. G. Sakhno
Analytical results for different dosage forms of ophthalmic drugs for the quality indicator “Particular contamination – subvisible particles” are presented. The possible analytical methods and regulatory requirements applicable to the quality of ophthalmic drugs for this parameter are discussed. Analytical results for subvisible particulate matter in ophthalmic dosage forms (40 samples) are presented
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Synthesis of 5,5′-(Disulfanediyl)bis[3-phenyl-1,3,4-thiadiazole-2(3H)-thione] and Study of Its Anti-Inflammatory Activity Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-16 G. S. Shakirzyanova, L. Yu. Izotova, O. Kh. Kholbekov, F. Yu. Zhaloliddinov, G. G. Rakhmonova, B. N. Babaev
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Acetaminophen and Thiosalicylic Acid Sensor Based on Carbon Paste Electrode Modified with Multi-Walled Carbon Nanotubes and Natural Deep Eutectic Solvent Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-16 Ebrahim Zarei, Maryam Vafadar, Alireza Asghari
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Low Molecular Weight NGF Mimetic Enhances the Overall Plasma Antioxidant Capacity in Rats with Streptozotocin-Induced Diabetes Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-15 S. V. Ivanov, R. U. Ostrovskaya, V. V. Olicheva, A. D. Savina, R. P. Terekhov, I. R. Ilyasov, I. A. Selivanova, T. A. Gudasheva
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The Prospects of 5-Androstenediol and its Synthetic Derivatives as Novel Radioprotective Drugs Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-15 M. E. Uspenskaya, T. A. Fedotcheva, A. N. Usenko, N. L. Shimanovsky
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The Prophylactic Effects of Isosteviol Aerosol Inhalation on Bronchial Asthma in Mice Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-15 Haihua Guo, Meng Li, Yue Lin, Zizhao Zhai, Guanlin Wang, Suqing Zhao
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Recent Advancements and Biological Activities of Triazole Derivatives: a Short Review Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-15 Shobha Rani, Shiva Teotia, Sumitra Nain
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Imidazo[4,5-a]acridines and Pyrazolo[4,3-a]acridines as a New Class of Urease Inhibitors: Synthesis, In Vitro Interactions, and Molecular Docking Studies Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-15 Javad Mohammadi, Mehdi Pordel, Mohammad Reza Bozorgmehr
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Synthesis and In Silico Prediction of the Molecular-Targeting Anti-EGFR Action of a Novel Dihydroacridinone Pharm. Chem. J. (IF 0.9) Pub Date : 2024-04-13 A. A. Epishkina, E. V. Bogoslovskaya, V. A. Pakina, A. I. Osipiantz, E. A. Kutorkina, E. A. Livin, O. M. Tumutolova, S. Ya. Skachilova, K. D. Blinov, E. V. Semeleva, D. N. Shimanovsky, I. V. Fedoseikin, M. V. Tolstov, E. V. Blinova, E. V. Shikh, D. S. Blinov
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Analgesic Effect of Comenic Acid in Acute Pain Models in Rats Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-25 A. L. Kovalenko, A. Yu. Petrov, N. A. Lycheva, Ye.A. Roshchina, Ye.B. Artyushkova, I. I. Bobyntsev, A. O. Vorvul
Comenic (5-hydroxy-4-oxo-4H-pyran-2-carboxylic) acid is regarded as a new analgesic agent. Comenic acid (CA) was studied in acute pain models using Wistar rats in the tail-flick and hot-plate tests. CA was administered in a single intramuscular injection 30 min before the tests. The reference drug (INN diclofenac) was administered at a dose of 6.6 mg/kg; the test drug (CA solution), at doses of 20
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Modernization of the Synthesis and Anti-Inflammatory Activity of 4,10-di(2-Ethoxyacetyl)-2,6,8,12-Tetraacetyl-2,4,6,8,10,12-Hexaazaisowurtzitane – An Innovative Non-Narcotic Analgesic Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-20
A modified method for the synthesis of a promising non-narcotic analgesic agent of the hexaazaisowurtzitane class with pronounced anti-inflammatory activity is described. Methods for reducing the cost of the target substance are considered. The physicochemical characteristics are described. The efficacy and safety of the synthesized agent are shown in several animal models.
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Design, Synthesis and Biological Evaluation of Amide Derivatives of Thiazole-Indole-Isoxazoles as Anticancer Agents Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-20 Ch. Karuna, Ch.Venkata Ramana Reddy, E. Laxminarayana
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Some Schiff Bases Containing Eugenol and Guaiacol: Comparison of Urease Inhibition and Anti-Helicobacter pylori Activities with Its Azo Analogs Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-20 Cihan Kantar, Nimet Baltaş, Şengül Alpay Karaoğlu, Selami Şaşmaz
To improve and develop our monotherapeutic approach for Helicobacter pylori infection, some Schiff base compounds containing eugenol and guaiacol were synthesized and their antioxidant capacities, urease enzyme inhibition, and Anti-Helicobacter pylori effect were investigated and compared with azo analogs in the literature. All Schiff base compounds have been found to have both stronger urease enzyme
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The Stability of Azithromycin in a Reconstituted Oral Suspension Under Various In-Home Storage Conditions Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19 Cengiz Gokbulut, Omer Faruk Sari, Busra Aslan Akyol, Fazilet Sen, Nurullah Geyguc
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Using Amino Acid-Silver Complexes Synthesized by Green Synthesis to Develop a New Antimicrobial Agent Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19
The antimicrobial properties and importance of Ag+ have been known since ancient times. However, resistance has started to develop against silver ions, which are used indiscriminately and in high concentrations. Therefore, it is necessary to synthesize new and different silver complexes. In this study, five new molecules were synthesized by green synthesis from amino acids. Firstly, the antimicrobial
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Synthesis and In Vitro Study of the Anticoagulation and Antiplatelet Activity of Abietic and Maleopimaric Acid Amides Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19 R. M. Sultanova, N. S. Khusnutdinova, Yu. G. Borisova, G. Z. Raskildina, S. A. Meshcheryakova, S. S. Zlotsky, Z. A. Valiullina, E. V. Karamova, A. V. Samorodov
The main goal of applying antiplatelet drugs is a reduced probability of thrombosis so that active substances that are superior to reference drugs in terms of the level and spectrum of their antiplatelet activity are being sought. Several amides of abietic and maleopimaric acids were synthesized and their anticoagulation and antiplatelet activity studied using the Born method and clotting tests. The
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Investigation and Characterization of Novel Biologically Active Secondary Metabolites from Melissa officinalis L. Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19 Pinar Goc Rasgele, Pinar Agyar Yoldas, Nisa Sipahi, Hilal Ucan
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Synthesis and Antiulcer Activity of Aromatic and Heterocyclic Amides of 3-O-Acetylglycyrrhetic Acid Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19 E. R. Karimova, N. S. Makara, T. A. Sapozhnikova, L. A. Baltina
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The Antioxidant Activity and the Protective Effect of Rosa canina L. Fruit Against Intestinal Inflammation Induced by Hyperhomocysteinemia in Mice Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19 Sara Khelfi, Sakina Zerizer, Chawki Bensouici, Souraya Tebibel, Zahia Kabouche
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A Supercritical Fluid Chromatography and Tandem Mass Spectrometry Method for the Simultaneous Quantification of Valsartan and Hydrochlorothiazide in Human Plasma Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-19 Y. K. Agrawal, Parthajyoti Gogoi, Prajesh Prajapati
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Water Soluble Curcuminoids: Encapsulation into Cyclodextrins and In-vitro Antioxidant Properties Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-18 Suvarna Shenvi, L. Shruthi, G. Chandrasekara Reddy, Anil Kush
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Microbiological Monitoring in Analysis of Drug Quality Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-18 M. V. Roshchina, O. V. Gunar, N. G. Sakhno
An informational and analytical review regarding microbiological monitoring in the analysis of pharmaceutical product quality is presented. Regulated types of microbiological monitoring are considered. General approaches to conducting environmental monitoring and their possible advantages and disadvantages are analyzed. Domestic and foreign regulations on monitoring rules are studied. Factors having
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Creation of Modified Forms of Amiodarone with Glycyrrhizic Acid and Its Monoammonium Salt and Study of Their Cytotoxicity on Hela Cells Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-18 Kh. A. Yuldashev, R. S. Esanov, H. T. Saidullaeva, V. V. Uzbekov, M. K. Salakhutdinova, Z. S. Khashimova, M. B. Gafurov, Yu. I. Oshchepkova, Sh. I. Salikhov
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Effect of Phenolic Acids and Flavonoids on Low Dose Caffeine-Induced Adipogenesis and Oxidative Stress in 3T3-L1 Adipocytes Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-18
Obesity is characterised by an excessive build-up of lipids and triglycerides in adipocytes. Phenolic acids and flavonoids have previously been shown to inhibit body weight increase and fat buildup in mice. This study investigated the anti-obesity effect of phenolics, syringic (SYA) and sinapic acid (SIA) and flavonoids hesperidin (HD) and chrysin (CR) along with caffeine (CAF) on 3T3-L1 cells. Anti-obesity
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Biological Activities and Drug-Likeness Properties of Phenol-Based Heterocyclic Compounds Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-18
The widespread use of small molecules having heterocyclic rings to design anticancer agents, and the antioxidant potential of their phenolic conjugates led us to investigate phenol-based heterocyclic compounds’ anticancer, antioxidant activities, and drug-likeness properties. While compounds were evaluated in regards to cancer and non-cancer cell lines by the MTT method, antioxidant effects were carried
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Phenolic Contents, Enzyme Inhibitory Activities, and Protective Effect of Aqueous Extract of Rosa Pisiformis Fruits Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-17 Suat Ekin, Mahire Bayramoglu Akkoyun, Hatice Kiziltas, Hasya Nazlı Gok, Gokhan Oto, Turan Akkoyun, Fevzi Ozgokce, Didem Deliorman Orhan
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Liposomal Pharmaceutical Products: Methods of Analytical Characterization and Quality Control Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-17 Z. S. Shprakh, N. I. Burdaev, L. L. Nikolaeva, N. D. Bunyatyan
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Development and Validation of a Quantitative Determination Method for Fluorothiazinone in Human Blood Plasma Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-17
An HPLC-MS/MS technique for quantitative determination of the new antibacterial drug fluorothiazinone in human blood plasma using an internal standard was developed and validated. The validation protocol proved the selectivity, accuracy, and precision of the method and the lack of significant carryover, matrix, and sample-dilution effects. The calibration curve was linear in the concentration range
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In Vitro Study of the Cytotoxic and Immunotropic Effects of Molnupiravir and Favipiravir Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-16
The effects of the antiviral drugs molnupiravir and favipiravir on the viability of human embryonic lung cells and the production of cytokines by peripheral blood leukocytes of healthy donors and patients with coronavirus infections were studied. Neither molnupiravir nor favipiravir nor their combination at concentrations up to 60 μg/mL was shown to have a significant effect on the survival of human
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Imipenem/Cilastatin Plasma Concentrations and Survival (Efficacy of Therapy) of Critically Ill Patients in Clinical Practice Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-16 O. V. Zhukova, V. A. Sudakov, O. A. Vorobyeva, N. N. Chesnokova, N. L. Shimanovsky
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Dispersive Solid Phase Extraction/Back-Extraction Using Carbon Nanotubes as Sorbent for HPLC/UV Determination of Ibuprofen in Human Blood Serum Samples Pharm. Chem. J. (IF 0.9) Pub Date : 2024-03-15 L. Sheikhian, E. Zahedinejad
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Nicotine-Loaded Polyvinyl Alcohol Electrospun Nanofibers as Transdermal Patches for Smoking Cessation: Formulation and Characterization Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-08 Nurul Huda Kamsani, Muhammad Shamsuri Hasan, Kamal Rullah, Muhammad Salahuddin Haris
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Mononuclear Metal Complexes of Moxifloxacin with Antacids: Synthesis, Spectroscopic Characterization, and Antimicrobial Activities Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-07 Mahwish Akhtar, Muhammad Imran
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Ternary Solid Dispersion of Celecoxib Produced by the Solvent Method with Improved Solubility and Dissolution Properties Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-07
Celecoxib, the first cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug, has a wide range of pharmacological effects, including anti-inflammatory, antirheumatic and antitumor effects. However, celecoxib’s poor solubility severely limits its clinical application. Thus, a novel ternary solid dispersion system was developed using PVP K30 and hydroxypropyl-β-cyclodextrin (HPβCD) as carrier
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Development and Validation of the Ultra-Performance Liquid Chromatography Method for Quantification of Belzutifan in Pharmaceutical Dosage Form Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-06 Pridhvi Krishna Gaddey, Raja Sundararajan
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Features of Planning and Conducting Bioequivalence Studies with an Adaptive Design for Drug Analogs of Endogenous Compounds Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-06 N. N. Eremenko, D. V. Goryachev
There is a constant interest in the study of drugs that are analogs of endogenous compounds. Guidelines for conducting bioequivalence studies are being updated. Official regulators are holding seminars on the development and study of generic drugs. The goal of the present study is to analyze approved protocols of clinical bioequivalence studies with an adaptive design for drugs that are analogs of
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Chloroacetates of Substituted 1H-Indol-5-,6-,7-Ylamines and Their Antimicrobial Activity Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-06 S. A. Yamashkin, I. S. Stepanenko, A. I. Kiryutina, T. N. Platkova
Water-soluble 1H-indol-5-, 6-, 7-ylammonium chloroacetates were obtained from the reaction of substituted 1H-indol-5-, 6-, 7-ylamines with chloroacetic acid; identified based on PMR, UV, and mass spectra; and screened in the laboratory for antimicrobial activity. All the tested compounds could suppress the growth of microorganism test strains at various minimum inhibitory concentrations (MICs). The
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Sclareol: Isolation, Structural Modification, Biosynthesis, and Pharmacological Evaluation – A Review Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-06 Salman Jameel, Khursheed Ahmad Bhat
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On Antimicrobial Preservatives in Soft Dosage Forms Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 L. V. Tsyganova, O. V. Gunar
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Synthesis, Structure, and Antiproliferative Activities of Complexes of Some Transition Metals with 5,7-Dichloro-8-Hydroxyquinoline-2-Carboxaldehyde-4-Phenyl-3-Thiosemicarbazone Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 Pham Thi Hai Linh, Mai Phuong Chi, Le Phuong Thao, Ninh Thi Minh Giang, Le Thi Hong Hai
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Kinetics of Omeprazole Release from Enteric Dosage Forms of Different Manufacturers Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 S. Yu. Serebrova, D. O. Kurguzova, L. M. Krasnykh, G. F. Vasilenko, E. Yu. Demchenkova, N. N. Eremenko, E. N. Kareva, A. B. Prokofiev
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Effect of Thioxypine and Its Components on Behavioral Despair in Potential Antidepressant Screening Tests Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 I. A. Volchegorskii, I. Y. Miroshnichenko, A. I. Sinitskii, S. I. Grobovoi, L. M. Rassokhina, R. R. Mihajlov
The effect of thioxypine (2-ethyl-6-methylpyridinol-3-yl thioctate) and its acyl and alcohol components on the duration of behavioral despair (BD) in the mouse tail suspension test according to L. Steru, et al. and the forced swimming test of mice and rats according to R. Porsolt, et al. was studied. Amitriptyline (a reference antidepressant) was used as a reference BD-contractor. The impact of the
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Substituted 1,3,5-Triazine Heterocycles: Synthesis and Antibacterial Activity Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 Archana Gahtori, Sarika Khandari, Shweta Pandey, Prashant Gahtori
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Determination of Biapenem in Human Blood Plasma by High-Performance Liquid Chromatography with UV Detection Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 A. M. Kazanova, S. K. Zyryanov, M. S. Chenkurov
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GC-MS Bioactives Profiling, Antibacterial and Cytotoxic Potential of Jamun (Syzygium cumini L.) Extracts Against Food-Borne Pathogen Salmonella enteritidis Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05
Salmonellosis is a major food-borne disease in humans worldwide caused by Salmonella enteritidis. Currently, selected phytochemicals are gaining attention as effective substitute therapeutics for management and control of microbial drug resistance. The present investigation appraises the antibacterial and cytotoxic activities of seed and leaf extract from Syzygium cumini against Salmonella enteritidis
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Flavonoids from the Leaves of Chromolaena odorata and Their α-Glucosidase Inhibitory Activity Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05
The leaf water extracts of C. odorata are used as an antidiabetic herbal drug in traditional medicine. The aim of this study was to determine flavonoids in the MeOH leaf extract of Chromolaena odorata (L.) R. M. King and H. Robinson (syn. Eupatorium odoratum L.) in Vietnam and evaluate their a-glucosidase inhibitory activity. Ten compounds including six known flavonoids (2, 4–6, 9, and 10), two known
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Stability Indicating RP-UPLC Method for the Quantitative Determination of Degradation Impurities of Benidipine Hydrochloride & Metoprolol Succinate in Combined Dosage Form Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05 Pranavkumar Shah, Sanjay Hadiyal, Jaydeep Lalpara, Gaurang Dubal, Bhavin Dhaduk
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Study of the Immunomodulatory Effect of Polysaccharides Isolated from Seeds of Turnip BRASSICA RAPA Pharm. Chem. J. (IF 0.9) Pub Date : 2024-02-05
The goal of this study was an evaluation of the immunomodulatory effect of polysaccharides isolated from the seeds of Brassica rapa. Apolysaccharide (BRP) consisting mainly of α-linked pyranose residues belonging to the arabinogalactan class was obtained. The number of antibody-forming cells (AFCs) per spleen increased to 9,160 ± 1477.06, 12,000 ± 3480.33, and 19,080 ± 12,391.6 [antibody-forming reaction