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Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-04-17 Herma C. Pierre, Chiraz Soumia M. Amrine, Michael G. Doyle, Amrita Salvi, Huzefa A. Raja, Jonathan R. Chekan, Andrew C. Huntsman, James R. Fuchs, Kebin Liu, Joanna E. Burdette, Cedric J. Pearce, Nicholas H. Oberlies
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Architecture of full-length type I modular polyketide synthases revealed by X-ray crystallography, cryo-electron microscopy, and AlphaFold2 Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-03-19 Saket R. Bagde, Chu-Young Kim
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Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-03-15 Stephanie C. Heard, Jaclyn M. Winter
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Cephalotane diterpenoids: structural diversity, biological activity, biosynthetic proposal, and chemical synthesis Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-03-14 Jin-Xin Zhao, Zhan-Peng Ge, Jian-Min Yue
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Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-03-11 Hanne Put, Hans Gerstmans, Hanne Vande Capelle, Maarten Fauvart, Jan Michiels, Joleen Masschelein
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Gold-catalyzed cyclization and cycloaddition in natural product synthesis Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-03-08 Boxu Lin, Tianran Liu, Tuoping Luo
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Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-03-07 Bichu Cheng, Qi Wang, Yi An, Fener Chen
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Plant peptides – redefining an area of ribosomally synthesized and post-translationally modified peptides Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-02-27 Jonathan R. Chekan, Lisa S. Mydy, Michael A. Pasquale, Roland D. Kersten
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Opportunities and challenges of RiPP-based therapeutics Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-02-27 Isabel P.-M. Pfeiffer, Maria-Paula Schröder, Silja Mordhorst
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The insect microbiome is a vast source of bioactive small molecules Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-02-27 Carlismari Oliveira Grundmann, Juan Guzman, Andreas Vilcinskas, Mônica Tallarico Pupo
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Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023 Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-02-23 Chao-Yi Wang, Jia-Qi Hu, De-Gao Wang, Yue-Zhong Li, Changsheng Wu
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Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-02-14 Giovanni Andrea Vitale, Christian Geibel, Vidit Minda, Mingxun Wang, Allegra T. Aron, Daniel Petras
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Specialized metabolite modifications in Brassicaceae seeds and plants: diversity, functions and related enzymes Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-02-07 Léa Barreda, Céline Brosse, Stéphanie Boutet, François Perreau, Loïc Rajjou, Loïc Lepiniec, Massimiliano Corso
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The Kornblum DeLaMare rearrangement in natural product synthesis: 25 years of innovation Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-31 Marc C. Kimber, Darren S. Lee
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Controllable skeletal reorganizations in natural product synthesis Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-31 Zeliang Zhang, Xiao Qian, Yucheng Gu, Jinghan Gui
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Marine natural products Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-29 Anthony R. Carroll, Brent R. Copp, Tanja Grkovic, Robert A. Keyzers, Michèle R. Prinsep
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Bacterial polyynes uncovered: a journey through their bioactive properties, biosynthetic mechanisms, and sustainable production strategies Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-29 Wei-Chih Chin, Yang-Zhi Zhou, Hao-Yung Wang, Yu-Ting Feng, Ru-Yin Yang, Zih-Fang Huang, Yu-Liang Yang
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Vallesamidine and schizozygane alkaloids: rearranged monoterpene indole alkaloids and synthetic endeavours Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-26 Xiangyu Zhang
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Biosynthesis of fungal terpenoids Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-24 Pan Luo, Jia-Hua Huang, Jian-Ming Lv, Gao-Qian Wang, Dan Hu, Hao Gao
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Promoter engineering of natural product biosynthetic gene clusters in actinomycetes: concepts and applications Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-23 Chang-Hun Ji, Hyun-Woo Je, Hiyoung Kim, Hahk-Soo Kang
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Correction: Future antimalarials from Artemisia? A rationale for natural product mining against drug-refractory Plasmodium stages Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-17 Alexandre Maciuk, Dominique Mazier, Romain Duval
Correction for ‘Future antimalarials from Artemisia? A rationale for natural product mining against drug-refractory Plasmodium stages’ by Alexandre Maciuk et al., Nat. Prod. Rep., 2023, 40, 1130–1144, https://doi.org/10.1039/D3NP00001J.
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Purine nucleoside antibiotics: recent synthetic advances harnessing chemistry and biology Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-10 Jonas Motter, Caecilie M. M. Benckendorff, Sarah Westarp, Peter Sunde-Brown, Peter Neubauer, Anke Kurreck, Gavin J. Miller
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Nitrile biosynthesis in nature: how and why? Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-09 Mingyu Liu, Shengying Li
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The shikimate pathway: gateway to metabolic diversity Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-03 Vikram V. Shende, Katherine D. Bauman, Bradley S. Moore
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Correction: Hot off the Press Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-03 Robert A. Hill, Andrew Sutherland
Correction for ‘Hot off the Press’ by Robert A. Hill et al., Nat. Prod. Rep., 2023, 40, 1816–1821, https://doi.org/10.1039/d3np90052e.
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The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide Nat. Prod. Rep. (IF 11.9) Pub Date : 2024-01-02 Fernando Baquero, Konstantinos Beis, David J. Craik, Yanyan Li, A. James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D. Hegemann
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The incredible story of ophiobolin A and sphaeropsidin A: two fungal terpenes from wilt-inducing phytotoxins to promising anticancer compounds Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-12-22 Antonio Evidente
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Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-12-22 Thilina U. Jayawardena, Natacha Merindol, Nuwan Sameera Liyanage, Isabel Desgagné-Penix
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Class II terpene cyclases: structures, mechanisms, and engineering Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-12-18 Xingming Pan, Jeffrey D. Rudolf, Liao-Bin Dong
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Chemistry and biology of specialized metabolites produced by Actinomadura Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-12-15 Yousef Dashti, Jeff Errington
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Harnessing the potential: advances in cyanobacterial natural product research and biotechnology Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-12-13 Martin Baunach, Arthur Guljamow, María Miguel-Gordo, Elke Dittmann
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Bacterial cyclophane-containing RiPPs from radical SAM enzymes Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-12-04 Chin-Soon Phan, Brandon I. Morinaka
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Discovery, synthesis, activities, structure–activity relationships, and clinical development of combretastatins and analogs as anticancer drugs. A comprehensive review Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-11-27 Sheo B. Singh
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The biosynthetic logic and enzymatic machinery of approved fungi-derived pharmaceuticals and agricultural biopesticides Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-11-22 Moli Sang, Peiyuan Feng, Lu-Ping Chi, Wei Zhang
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Dehydroamino acid residues in bioactive natural products Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-11-09 Shan Wang, Kewen Wu, Ya-Jie Tang, Hai Deng
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Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-11-06 Evan T. Miller, Oleg V. Tsodikov, Sylvie Garneau-Tsodikova
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Natural ten-membered lactones: sources, structural diversity, biological activity, and intriguing future Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-10-27 Vsevolod Dubovik, Anna Dalinova, Alexander Berestetskiy
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Polyamine-containing natural products: structure, bioactivity, and biosynthesis Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-10-24 Qingshan Long, Wen Zhou, Haibo Zhou, Ying Tang, Wu Chen, Qingshu Liu, Xiaoying Bian
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Recent asymmetric synthesis of natural products bearing an α-tertiary amine moiety via temporary chirality induction strategies Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-10-17 Hongjun Jeon, Jae Hyun Kim, Sanghee Kim
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Huperzine alkaloids: forty years of total syntheses Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-10-11 Bichu Cheng, Lili Song, Fener Chen
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Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-10-09 Zhanpin Zhu, Ruibing Chen, Lei Zhang
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Chemistry and bioactivity of lindenane sesquiterpenoids and their oligomers Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-10-04 Jun Luo, Danyang Zhang, Pengfei Tang, Nan Wang, Shuai Zhao, Lingyi Kong
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Embracing the era of antimicrobial peptides with marine organisms Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-09-25 Pengyu Chen, Ting Ye, Chunyuan Li, Praveen Praveen, Zhangli Hu, Wenyi Li, Chenjing Shang
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Chemistry, biosynthesis and biology of floral volatiles: roles in pollination and other functions Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-09-04 Stefan Dötterl, Jonathan Gershenzon
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Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-08-29 Li-Hong Yan, Xin Li, Bin-Gui Wang
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The role of Caenorhabditis elegans in the discovery of natural products for healthy aging Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-08-16 Benjamin Kirchweger, Julia Zwirchmayr, Ulrike Grienke, Judith M. Rollinger
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Structural enzymology of iterative type I polyketide synthases: various routes to catalytic programming Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-08-15 Jialiang Wang, Zixin Deng, Jingdan Liang, Zhijun Wang
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Natural products as anthelmintics: safeguarding animal health Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-08-09 Angela A. Salim, Mark S. Butler, Mark A. T. Blaskovich, Ian R. Henderson, Robert J. Capon
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Industrial total synthesis of natural medicines Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-08-09 Xiao-Yu Liu, Yong Qin
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Engineering yeast for the production of plant terpenoids using synthetic biology approaches Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-07-31 Jean-Alexandre Bureau, Magdalena Escobar Oliva, Yueming Dong, Codruta Ignea
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Machine learning-assisted structure annotation of natural products based on MS and NMR data Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-07-31 Guilin Hu, Minghua Qiu
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Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-07-26 Christina Braun, Lukas Martin Wingen, Dirk Menche
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Anthrol reductases: discovery, role in biosynthesis and applications in natural product syntheses Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-07-21 Anshul Rajput, Tanaya Manna, Syed Masood Husain
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From plant to cancer drug: lessons learned from the discovery of taxol Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-07-14 Nadja B. Cech, Nicholas H. Oberlies
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Recent advances in the discovery of plant-derived antimicrobial natural products to combat antimicrobial resistant pathogens: insights from 2018–2022 Nat. Prod. Rep. (IF 11.9) Pub Date : 2023-07-13 Sunmin Woo, Lewis Marquez, William J. Crandall, Caitlin J. Risener, Cassandra L. Quave