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Oxidized sodium alginate hydrogel-mouse nerve growth factor sustained release system promotes repair of peripheral nerve injury J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-17 Yuming Sun, Xiangyu Sun, Ruiqi Wang, Yuhang Xing, Xiang Ma, Jie Yue, Min Zhang, Yuezhu Wang, Weiming Tian, Guangping Jing
In recent years, mouse nerve growth factor (mNGF) has emerged as an important biological regulator to repair peripheral nerve injury, but its systemic application is restricted by low efficiency an...
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Design, optimization, and evaluation of topical gel of Cardiospermum halicacabum and Ricinus communis L. leaves extract for the treatment of rheumatoid arthritis J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-13 Chirag Ojha, Pankaj Sharma, Vinay Jain
This research aims to develop and assess the anti-arthritic properties of a topically herbal gel including leaf extracts from Cardiospermum halicacabum and Ricinus communis L. in rats. Utilizing ge...
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Therapeutic effect of ZnO NPs–polyhexanide-hydrogel on Staphylococcus aureus-induced skin wound infection in mice J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-13 Junhe Zhu, Yuxin Li, Yixin Tang, Yike Fan, Shiyi Dai, Awn Abbas, Funeng Xu, Xianxiang Wang, Wei Zhang, Yilei Zheng, Gang Shu
Nanometer zinc oxide (ZnONPs) offers strong antibacterial, wound healing, hemostatic benefits, and UV protection. Additionally, poly(hexamethylene biguanide)hydrochloride (PHMB) is an environmental...
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Fabrication and mechanical modelling of dissolvable PVA/PVP composite microneedles with biocompatibility for efficient transdermal delivery of ibuprofen J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-08 Min Xiao, Zifeng Wang, Yanru An, Yingqi Dai, Xinghao Wang, Zhigang Zhu
Microneedles offer minimally invasive, user-friendly, and subcutaneously accessible transdermal drug delivery and have been widely investigated as an effective transdermal delivery system. Ibuprofe...
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Production and characterization of polyvinyl alcohol films containing essential oil J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-08 Nihan Ünlü, Arzu Özgen, Canan Aksu CANBAY
Packaging plays an important role in protecting foodstuffs against physicochemical damage and microbial activity, as well as extending shelf life. In recent years, petrochemical compounds that caus...
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Development and characterization of ceramic-polymeric hybrid scaffolds for bone regeneration: incorporating of bioactive glass BG-58S into PDLLA matrix J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-03 Veronica Cristina Pêgo Fiebig Aguiar, Rayssa do Nascimento Bezerra, Kennedy Wallace dos Santos, Isabela dos Santos Gonçalves, Karen Julie Santos Grancianinov Costa, Diogo Ponte Lauda, Tiago Moreira Bastos Campos, Renata Falchete do Prado, Luana Marotta Reis de Vasconcellos, Ivone Regina de Oliveira
In recent years, there has been a notable surge of interest in hybrid materials within the biomedical field, particularly for applications in bone repair and regeneration. Ceramic-polymeric hybrid ...
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Impact of changes in collagen construction and molecular state on integrin – binding properties J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-04 Huizhi Kou, Qingqiu Han, Huihui Zhang, Chengzhi Xu, Lixia Liao, Yuanjing Hou, Haibo Wang, Juntao Zhang
The interaction between the integrin and collagen is important in cell adhesion and signaling. Collagen, as the main component of extracellular matrix, is a base material for tissue engineering con...
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Recent advances in wearable flexible electronic skin: types, power supply methods, and development prospects J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-03 Hongying Tian, Chang Liu, Huimin Hao, Xiangrong Wang, Hui Chen, Yilei Ruan, Jiahai Huang
In recent years, wearable e-skin has emerged as a prominent technology with a wide range of applications in healthcare, health surveillance, human–machine interface, and virtual reality. Inspired b...
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Self-assembling peptide hydrogel scaffold integrating stem cell-derived exosomes for infected bone defects J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-04 Haiyan Xu, Jing Feng, Ning Dai, Qiong Han, Bei Zhou, Guiyun Yang, Rui Hu
Infected bone defect (IBD) is a great challenge in orthopedics, which involves in bone loss and infection. Here, a self-assembling hydrogel scaffold (named AMP-RAD/EXO), integrating antimicrobial p...
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Correction J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-04-04
Published in Journal of Biomaterials Science, Polymer Edition (Ahead of Print, 2024)
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Evaluating a promising methylcellulose hydrogel for enhanced diabetic foot ulcer therapy through comprehensive preclinical studies J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-27 Priya Patel, Sanika Dongre, Alkesh Patel, Gayatri Patel
The present research focuses on formulating and evaluating hydrogels modified with crosslinking agents using methylcellulose to treat diabetic foot ulcers (DFU). Methylcellulose hydrogels are prepa...
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Synergetic approaches of fucoidan and trabectedin complex coated PLGA nanoparticles effectively suppresses proliferation and induce apoptosis for the treatment on non-small cell lung cancer J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-26 Qingliang Fang, Guangmin Mao, Lei Wang, Yukai Gu, Renjie Song, Xianglian Gu, Song Lu, Xiaoli Li
Traditional methods of treating lung cancer have not been very effective, contributing to the disease’s high incidence and death rate. As a result, Fn/Tn-PLGA NPs, a novel directed fucoidan and tra...
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Emulsion template fabricated heterogeneous bilayer gelatin-based scaffolds with sustained-delivery of lycium barbarum glycopeptide for periodontitis treatment J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-26 Siqi He, Nan Wen, Xun Chen, Cong Liu, Xun Xiao, Xinlun Li, Lun Yuan, Yandong Mu
Periodontitis is a chronic inflammatory disease raising the risks of tooth-supporting structures destruction and even tooth loss. The way to reconstruct periodontal bone tissues in inflammatory mic...
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Fabrication, evaluation, and enhanced penetration of vinyl and cellulose-engineered transdermal patch of nifedipine using essential oil as penetration enhancer J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-19 Stabak Das, Sudip Das, Sanjib Bahadur, Maitreyee Mukherjee, Gouranga Nandi, Sreejan Manna
The aim of this study was to develop and evaluate the transdermal patch formulations of nifedipine. The patch formulations containing nifedipine were prepared and optimized with different ratios of...
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BMSCs-driven graphite oxide-grafted-carbon fibers reinforced polyetheretherketone composites as functional implants: in vivo biosafety and osteogenesis J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-17 Wen Qin, Tong Xing, Shengnan Qin, Bin Tang, Weiyi Chen
Mesenchymal stem cells (MSCs) are increasingly becoming a potential treatment approach for bone injuries due to the multi-lineage differentiation potential, ability to recognize damaged tissue site...
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Hydroxyl silicone oil grafting onto a rough thermoplastic polyurethane surface created durable super-hydrophobicity J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-15 Miaomiao Tan, Fuping Wang, Jinlan Yang, Zhengpeng Zhong, Guobao Chen, Zhongmin Chen
Indwelling medical catheters are frequently utilized in medical procedures, but they are highly susceptible to infection, posing a vital challenge for both health workers and patients. In this stud...
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Promoting the healing of diabetic wounds with an antimicrobial gel containing AgNPs with anti-infective and anti-inflammatory properties J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-09 Yanyan Zhou, Haiyan Huang, Gong Chen, Qi Yuan, Jingyuan Ren, Jiashen Wu, Yuchun Lin, Zhongning Lin, Ling Xu
Diabetic wounds are prone to develop chronic wounds due to bacterial infection and persistent inflammatory response. However, traditional dressings are monofunctional, lack bioactive substances, ha...
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Blood compatibility of poly(propylene glycol diester) and its water structure observed by differential scanning calorimetry and 2H-nuclear magnetic resonance spectroscopy J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-08 Akira Mochizuki, Ayaka Udagawa, Yuko Miwa, Yoshiki Oda, Konatsu Yoneyama, Chihiro Okuda
Recently, we applied solution 2H-nuclear magnetic resonance spectroscopy (2H NMR) to analyze the water (deuterium oxide, D2O) structure in several biopolymers at ambient temperature. We established...
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An overview of nasal cartilage bioprinting: from bench to bedside J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-05 Hosein Rostamani, Omid Fakhraei, Niloufar Zamirinadaf, Mehran Mahjour
Nasal cartilage diseases and injuries are known as significant challenges in reconstructive medicine, affecting a substantial number of individuals worldwide. In recent years, the advent of three-d...
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Kaolin loaded gelatin sponges for rapid and effective hemostasis and accelerated wound healing J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-03 Jing Zhou, Ming Li, Jing Chang, Bo Chen, Tianbing Wang, Wei Guo, Yanhua Wang
Severe trauma with massive active blood loss, including liver and spleen rupture, arterial bleeding and pelvic fracture, will lead disability, malformation and even death. Therefore, it is very imp...
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Correction J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-05
Published in Journal of Biomaterials Science, Polymer Edition (Vol. 35, No. 6, 2024)
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Formulation and evaluation of dissolving microneedle for transdermal delivery of piperine: the effect of polymers concentration J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-04 Andi Nur Aisyah, Andi Dian Permana, Elly Wahyudin, Diany Elim, Mukarram Mujahid, Ikbal Ikbal, Nana Novriana Payung Datu, Muhammad Aswad
This research aims to develop the formulation of Dissolving Microneedle Piperine (DMNs PIP) and evaluate the effect of polymer concentration on characterisation and permeation testing results in ex...
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An imprint-based approach to replicate nano- to microscale roughness on gelatin hydrogel scaffolds: surface characterization and effect on endothelialization J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-03-03 Ali Salehi, Stefanie Sprejz, Holger Ruehl, Monilola Olayioye, Giorgio Cattaneo
Biologization of biomaterials with endothelial cells (ECs) is an important step in vascular tissue engineering, aiming at improving hemocompatibility and diminishing the thrombo-inflammatory respon...
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Microfluidic nanoprecipitation of PEGylated PLGA nanoparticles with rapamycin and performance evaluation J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-29 Jiahao Guo, Wenjing Dai, Weiqian Wu, Shiya Zhuang, Huan Zhang, Lian Cen
Rapamycin (RAP) is currently being developed as potential antibreast cancer drug. However, its poor solubility completely limits its use. The aim of this study was to develop polyethylene glycol-po...
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Correction J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-25
Published in Journal of Biomaterials Science, Polymer Edition (Ahead of Print, 2024)
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Effects of liquid-to-solid ratio and gamma irradiation on the rheology and cytocompatibility of a beta-tricalcium phosphate-based injectable bone substitute J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-24 Deniz Ozdil, Gülçin Günal, Atakan Tevlek, Halil Murat Aydin
Injectable bone substitute (IBS) materials are commonly used to fill irregular-shaped bone voids in non-load-bearing areas and can offer greater utility over those which are in prefabricated powder...
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Investigation of biosensing properties in magnetron sputtered metallized UV-curable polymer microneedle electrodes J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-22 Baoling Jia, Tiandong Xia, Xiaohui Wang, Yangtao Xu, Bei Li
Direct management and assessment of metal film properties applied to polymer microneedle (MN) biosensors remains difficult due to constraints inherent to their morphology. By simplifying the three-...
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Electrospun membranes of diselenide-containing poly(ester urethane)urea for in situ catalytic generation of nitric oxide J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-22 Yong Gao, Shan Bai, Kongying Zhu, Xiaoyan Yuan
Nitric oxide (NO) plays an important role as a signalling molecule in the biological system. Organoselenium-coated or grafted biomaterials have the potential to achieve controlled NO release as the...
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Tissue engineering in otology: a review of achievements J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-22 Reza Kaboodkhani, Davood Mehrabani, Armaghan Moghaddam, Iman Salahshoori, Hossein Ali Khonakdar
Tissue engineering application in otology spans a distance from the pinna to auditory nerve covered with specialized tissues and functions such as sense of hearing and aesthetics. It holds the pote...
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An optimized chitosan/alginate-based microencapsulation of lime peel essential oil and its application as an antibacterial textile J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-10 Nastiti Nur Indriyani, Jamaludin Al-Anshori, Tatang Wahyudi, Mohamad Nurzaman, Sarifah Nurjanah, Nandang Permadi, Euis Julaeha
A functional textile immobilized by microcapsules of the lime peel essential oils of C. aurantifolia (LPEO) was prepared and characterized. A varied amount of Chitosan/Alginate (CH/AG) ratios, foll...
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Vitamin K (Menadione)-incorporated chitosan/alginate hydrogel as a novel product for periorbital hyperpigmentation J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-10 Zahra Rezanejad Gatabi, Seyyed Mobin Rahimnia, Katayoun Morteza-Semnani, Rezvan Yazdian-Robati, Seyyed Mohammad Hassan Hashemi, Majid Saeedi
The possibility of controlling periorbital hyperpigmentation disorders is one of the most important research goals in cosmetic preparations. In the current investigation, 1% vitamin K (Vit K) was i...
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Advances in injectable hydrogels for radiation-induced heart disease J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-10 Lu-Yao Zhao, Xin-Yue Wang, Mei-Ling Wen, Ning-Ning Pan, Xing-Qi Yin, Mei-Wen An, Li Wang, Yang Liu, Jian-Bo Song
Radiological heart damage (RIHD) is damage caused by unavoidable irradiation of the heart during chest radiotherapy, with a long latency period and a progressively increasing proportion of delayed ...
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Correction J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-09
Published in Journal of Biomaterials Science, Polymer Edition (Ahead of Print, 2024)
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Keratin-containing scaffolds for tissue engineering applications: a review J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-13 Sanaz Soleymani Eil Bakhtiari, Saeed Karbasi
In tissue engineering and regenerative medicine applications, the utilization of bioactive materials has become a routine tool. The goal of tissue engineering is to create new organs and tissues by...
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The response of human osteoblasts on bovine xenografts with and without hyaluronate used in bone augmentation J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-12 Syed Saad Bin Qasim, Branko Trajkovski, Gregor-Georg Zafiropoulos
The aim of the in vitro study was to asses the effect of hyaluronate in conjunction with bovine derived xenografts on the viability, proliferation on day 4, 7 and 10, expression of early osteogenic...
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Fibroblasts and polymer composition are essential for bioengineering of airway epithelium on nonwoven scaffolds J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-04 Olga A. Romanova, Olga I. Klein, Elena V. Sytina, Stanislav G. Rudyak, Timofey D. Patsaev, Timur H. Tenchurin, Alexander Yu Grigorchuk, Tatiana S. Demina, Sergey N. Chvalun, Andrey A. Panteleyev
To make tissue engineering a truly effective tool, it is necessary to understand how the patterns of specific tissue development are modulated by and depend on the artificial environment. Even the ...
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Electrospun nanofibers as advanced wound dressing materials: comparative analysis of single-layered and multilayered nanofibers containing polycaprolactone, methylcellulose, and polyvinyl alcohol J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-04 Bindu Kumari Yadav, Nilay Solanki, Gayatri Patel
The dressing materials that provide surface protection, bacteriostatic activities, and tissue regeneration are important for the treatment and management of complex wounds. This study aimed to eval...
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Microfluidic-assisted preparation of PLGA nanoparticles loaded with insulin: a comparison with double emulsion solvent evaporation method J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Maryam Kouhjani, Mahmoud Reza Jaafari, Hossein Kamali, Amirhossein Abbasi, Mohsen Tafaghodi, Seyed Ali Mousavi Shaegh
Poly lactic-co-glycolic acid (PLGA) is an ideal polymer for the delivery of small and macromolecule drugs. Conventional preparation methods of PLGA nanoparticles (NPs) result in poor control over N...
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Effect of surface modification of graphene oxide with a reactive silane coupling agent on the mechanical properties and biocompatibility of acrylic bone cements J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Geovanny Ayora-Gutiérrez, Antonio D. Abreu-Rejón, Alejandro May-Pat, Cynthia Guerrero-Bermea, Víctor Vladimir Fernández‑Escamilla, Nayeli Rodríguez-Fuentes, José M. Cervantes-Uc, Jorge Alonso Uribe-Calderon
Carbon allotrope materials (i.e. carbon nanotubes (CNTs), graphene, graphene oxide (GO)), have been used to reinforce acrylic bone cement. Nevertheless, the intrinsic incompatibility among the abov...
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Graphene oxide-encapsulated baghdadite nanocomposite improved physical, mechanical, and biological properties of a vancomycin-loaded PMMA bone cement J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Mohamadreza Tavakoli, Aliakbar Najafinezhad, Marjan Mirhaj, Saeed Karbasi, Jaleh Varshosaz, Mastafa H. Al-Musawi, Pegah Madaninasab, Fariborz Sharifianjazi, Morteza Mehrjoo, Saeideh Salehi, Nafise Kazemi, Sepideh Nasiri-Harchegani
Polymethyl methacrylate (PMMA) bone cement is commonly used in orthopedic surgeries to fill the bone defects or fix the prostheses. These cements are usually containing amounts of a nonbioactive ra...
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Injecting hope: chitosan hydrogels as bone regeneration innovators J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Gayatri Vaidya, Sheersha Pramanik, Ammar Kadi, Ahmed Raheem Rayshan, Bassam M. Abualsoud, Mohammad Javed Ansari, Rehana Masood, Jacob Michaelson
Spontaneous bone regeneration encounters substantial restrictions in cases of bone defects, demanding external intervention to improve the repair and regeneration procedure. The field of bone tissu...
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Advantages of nanomedicine over the conventional treatment in Acute myeloid leukemia J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Gopalarethinam Janani, Agnishwar Girigoswami, Koyeli Girigoswami
Leukemia is a cancer of blood cells that mainly affects the white blood cells. In acute myeloid leukemia (AML) sudden growth of cancerous cells occurs in blood and bone marrow, and it disrupts nor...
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The efficient role of sodium alginate-based biodegradable dressings for skin wound healing application: a systematic review J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Carina Maiara da Silva, Rui L. Reis, Vitor M. Correlo, Vanusca Dalosto Jahno
Injuries and damage to the skin can be caused by different reasons throughout human life. The use of sodium alginate in tissue dressing has been highly studied due to its intrinsic properties, incl...
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Graphene oxide nanosheets conjugated PEG-Glu-Lys-Glu copolymer drug delivery system improves drug-loading rates and enables reduction-sensitive drug release and drug tracking J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Qinming Xu, Hui Chen, Junming Zhu, Xing Li, Jingang Yang, Xiaocui Deng, Qingmei Yuan
In this study, the PEG-Glu-Lys-Glu copolymer drug delivery system (GO/PEG-Glu-Lys-Glu) is prepared using glutamate-lysine-glutamate (Glu-Lys-Glu) modified polyethylene glycol (PEG) and connected gr...
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Overcoming challenges in dermal and transdermal delivery of herbal therapeutics with polymeric microneedles J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Anusha V. M., Sarasija Suresh, Avichal Kumar, Paranjyothy K., Reena N. M., Srinath Rangappa, S. Narasimha Murthy, Shivakumar H.N.
Natural products are generally preferred medications owing to their low toxicity and irritancy potential. However, a good number of herbal therapeutics (HT) exhibit solubility, permeability and sta...
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Effects of propolis coating on antibacterial resistance of intrauterine devices J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-02-01 Alparslan Deniz, Tunca Karasu, Neslihan İdil, Lokman Uzun
Intrauterine devices (IUDs) are widely used in preventing fertilization as contracepting devices. In market, they are produced as T-shaped polyethylene (or propylene) and metal (especially copper) ...
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Improving bone regeneration with electrospun antibacterial polycaprolactone/collagen/polyvinyl pyrrolidone scaffolds coated with hydroxyapatite and cephalexin delivery capability J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Elahe Gholipour Choubar, Mohammad Hossein Nasirtabrizi, Farshid Salimi, Ali Sadeghianmaryan
Electrospinning is a facile popular method for the creation of nano-micro fibers tissue engineering scaffolds. Here, polycaprolactone (PCL)/collagen (COL): polyvinyl pyrrolidone (PVP) scaffolds (PC...
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Silver-doped hydroxyapatite laden chitosan–gelatin nanocomposite scaffolds for bone tissue engineering: an in-vitro and in-ovo evaluation J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Sakchi Bhushan, Sandhya Singh, Tushar Kanti Maiti, Leena R. Chaudhari, Meghnad G. Joshi, Dharm Dutt
Despite the advancements in bone tissue engineering, the majority of implant failures are caused due to microbial contamination. So, efforts are being made to develop biomaterial with antimicrobial...
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Chondrogenesis of mesenchymal stromal cells on the 3D printed polycaprolactone/fibrin/decellular cartilage matrix hybrid scaffolds in the presence of piascledine J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-30 Ali Honarvar, Mohsen Setayeshmehr, Sho’leh Ghaedamini, Batool Hashemibeni, Lorenzo Moroni, Saeed Karbasi
Nowadays, cartilage tissue engineering (CTE) is considered important due to lack of repair of cartilaginous lesions and the absence of appropriate methods for treatment. In this study, polycaprolac...
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Towards a sustainable chitosan-based composite scaffold derived from Scylla serrata crab chitosan for bone tissue engineering J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Agustina Setiawati, Kateri Tricahya, Florentinus Dika Octa Riswanto, Yohanes Dwiatmaka
Bone tissue engineering offers a novel therapy for repairing bone defects or fractures. However, it is becoming increasingly challenging because an ideal scaffold should possess a similar porous st...
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Physicochemical modifications in microwave-irradiated chitosan: biopharmaceutical and medical applications J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-29 Doaa Elsayed Mahmoud, Nashiru Billa
Biopharmaceutical and biomedical applications of chitosan has evolved exponentially in the past decade, owing to its unique physicochemical properties. However, further applications can be garnered...
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Curcumin-loaded pH-sensitive carboxymethyl chitosan nanoparticles for the treatment of liver cancer J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-29 Xinyu Yang, Dongdong Meng, Ning Jiang, Chaoxing Wang, Jinbo Zhang, Yanqiu Hu, Jiaming Lun, Rui Jia, Xueyun Zhang, Weitong Sun
In this study, the pH-responsive API-CMCS-SA (ACS) polymeric nanoparticles (NPs) based on 1-(3-amino-propyl) imidazole (API), stearic acid (SA), and carboxymethyl chitosan (CMCS) were fabricated fo...
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Osteopontine-derived functional fragments coupled to RADA16 self-assembled peptide hydrogels promotes bone and vascular regeneration in vivo J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-29 Yong Li, Yao Tang, LiFu Chen, HaiTao Li, Hong Wang, Jian Wang
Biomaterial scaffolds have been widely used in tissue engineering. A functionalized self-assembled peptide scaffold named RADA16-OPD was designed by linking the short functional motif of osteoponti...
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Type I collagen concentration affects neurite outgrowth of adult rat DRG explants by altering mechanical properties of hydrogels J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Uyen N. Nguyen, Fei San Lee, Sydney M. Caparaso, Jack T. Leoni, Adan L. Redwine, Rebecca A. Wachs
Type I collagen is a predominant fibrous protein that makes up the extracellular matrix. Collagen enhances cell attachment and is commonly used in three-dimensional culture systems, to mimic the na...
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An injectable PC10ARGD/Cu2+/DOX hydrogel for combined chemodynamic and chemotherapy of tumors J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Jie Yang, Xiao-Jie Wang, Si-Mei Li, Dong-Xue Jiang, Yu-Xin Liu, Yan Huang, Di-Di Dong, Wei Hu, Bo Liu
Nowadays, chemotherapy is a common clinical treatment for cancer, but it still faces many limitations and challenges. Therefore, the combination of chemotherapy and other treatments often enhances ...
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Biomedical applications of natural and synthetic polymer based nanocomposites J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Harini A, Sharon P. S. Sofini, Deepika Balasubramanian, Agnishwar Girigoswami, Koyeli Girigoswami
Various nanomaterials have been studied for their biomedical application in recent years. Among them, nanocomposites have a prominent medical application in the prevention, diagnosis, and treatment...
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Exploring the potential of pH-sensitive polymers in targeted drug delivery J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Shyam Sudhakar Gomte, Tejas Girish Agnihotri, Shivani Khopade, Aakanchha Jain
The pH-sensitive polymers have attained significant attention in the arena of targeted drug delivery (TDD) because of their exceptional capability to respond to alteration in pH in various physiolo...
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Folate receptor-mediated delivery system based on chitosan coated polymeric nanoparticles for combination therapy of breast cancer J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-25 Sajjad Jamali, Behzad Jamali, Fatemeh Abedi, Mohsen Firoozrai, Soodabeh Davaran, Sevil Vaghefi Moghaddam
Combination therapy using two or more drugs with different mechanisms of action is an effective strategy for treating cancer. This is because of the synergistic effect of complementary drugs that e...
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Preparation of pH-responsive polyurethane nano micelles and their antibacterial application J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-24 Mao-Lan Zhang, Gui-Ping Zhang, Hong-Shuo Ma, Yu-Zhu Pan, Xiao-Ling Liao
Considering the differences in pH between bacterial infection microenvironment and normal tissues, a series of pH-responsive drug-release amphiphilic polyurethane copolymers (DPU-g-PEG) have been p...
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Preparation of bio-synthesized Ag nanoparticles and assessment of their antidiabetic and antioxidant potential against STZ-induced diabetic albino rats J. Biomater. Sci. Polym. Ed. (IF 3.6) Pub Date : 2024-01-17 Karuppannan P., Saravanan K., Ashokkumar M., Chukwuebuka Egbuna
Bio-synthesized silver nanoparticles (AgNPs) were successfully obtained using the leaf extract from Ventilago maderaspatana. Extensive analysis was conducted to evaluate the physical and chemical c...