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Diagnosis of bone marrow involvement in angioimmunoblastic T-cell lymphoma should be based on both [18F]FDG-PET/CT and bone marrow biopsy findings Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-16 Xinyu Liang, Chunli Yang, Minggang Su, Liqun Zou
During the initial staging of certain lymphoma subtypes, 18 F-fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG-PET/CT) has become an alternative to bone marrow biopsy (...
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The use of essential oils in atopic dermatitis: a review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-16 Hanisah Azhari, Ng Shiow Fern, Razifah Mohd Razali, Hooi Leong Loo
Atopic dermatitis (AD) has become a common childhood disease that affects a large number of children worldwide and has become a chronic skin disease that cause a huge economical and psychological d...
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Lipid clinic experience with bempedoic acid in 3 UK centres Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-15 Agnieszka Jakubowska, Wiaam Al Hasani, Jamal Williams, Zofia MacMahon, Bryan Balbas, Martin A. Crook, Adie Viljoen, Timothy M. Reynolds, Anthony S. Wierzbicki
Objective: Novel lipid-lowering therapies are being introduced. Few studies exist of the real-world effectiveness of adenosine-tri-phosphate citrate lyase inhibition with bempedoic acid.Methods: Th...
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Development and validation of a score assessing the risk of severe asthma in primary care Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-11 Francesco Lapi, Iacopo Cricelli, Marco Gorini, Angela Pellegrino, Marzio Uberti, Claudio Cricelli
To develop and validate the Asthma Severity-Health Search (AS-HScore), predicting severe asthma risk in Italian primary care. According to the current asthma treatment guidelines, the AS-HScore int...
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Iraqi experts consensus on the management of relapsing remitting multiple sclerosis in adults Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-11 Hayder K. Hassoun, Anmar Oday Hatem, Akram Al-Mahdawi, Sarwer Jamal Al-Bajalan, Ali Kadim Karim, Sarmad Abdulrasool Al-Mashta, Saif Mohammed Tawfeeq, Majeed Salih Hamad, Nawfal M. Sheaheed, Samer Mohammed Ridha, Murad Al-Naqshbandi, Hasan Aziz Al-Hamadani
In Iraq, a lack of evidence-based management protocols for diagnosing, treating, and managing multiple sclerosis (MS) poses risks of suboptimal outcomes and clinical practice variability and potent...
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Risk factors for recurrence in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative early breast cancer in Japan: a systematic literature review and meta-analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-10 Naoki Miyazaki, Toshiki Iwasaki, Hitomi Sakai, Rurina Watanuki, Yoshinori Tanizawa, Zhihong Cai, Tsutomu Kawaguchi, Junji Tsurutani, Kengo Nagashima
The clinicopathological factors indicating risk of recurrence are used to guide the choice of perioperative therapy in patients with breast cancer. Although several risk factors for recurrence have...
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Understanding preferences for receiving health communications and information about clinical trials: a cross-sectional study among US adults Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-10 Dalia Majumdar, Diane Webb, Stephanie Parsons, Elizabeth M Selwan-Lewis, Trisha Rettig, Emily Chastain, Winifred Obanor, Rob Birnberg, Amy Kuang
Objective: Effective health communication is critical for understanding and acting on health information. This cross-sectional study explored participants' understanding of their health condition, ...
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Real-world clinical outcomes and healthcare costs in patients with Crohn’s disease treated with vedolizumab versus ustekinumab in the United States Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-08 Michael Chiorean, Jeanne Jiang, Ninfa Candela, Grace Chen, Hela Romdhani, Dominick Latremouille-Viau, Sherry Shi, Rebecca Bungay, Annie Guerin, Tao Fan
To compare real-world treatment persistence, dose escalation, rates of opportunistic or serious infections, and healthcare costs in patients with Crohn’s disease (CD) receiving vedolizumab (VDZ) vs...
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Pregnancy and fetal outcomes following paternal exposure to glatiramer acetate Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-05 Sigal Kaplan, Claudia Florentina Dragut, Andra Ghimpeteanu
This study aimed to examine pregnancy and fetal outcomes following paternal exposure to glatiramer acetate (GA).Pregnancy reports of paternal GA-exposure at time of conception from 2001 − 2022 were...
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Burden of Wilson Disease among patients and care partners in the United States: results from a cross-sectional survey Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-03 Jon Vlasnik, M. Janelle Cambron-Mellott, Halley Costantino, Mary Kunjappu
Objective: This study assessed the burden of Wilson Disease (WD) among patients and care partners (WD-CPs) in the US and compared it to a US general population of adults (GPs) and care partners (GP...
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Real-world effectiveness of long-acting injectable vs. oral antipsychotics in patients with bipolar I disorder: a 1-year retrospective observational study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-01 Şükrü Alperen Korkmaz, Sümeyye Gürler
Long-acting injectable (LAI) antipsychotics are recommended in the treatment non-adherence. Despite the widespread use of LAI antipsychotics, there is limited data on clinical outcomes in bipolar I...
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Skin disorders in women with poor obstetric history: MTHFR polymorphisms and importance of preconceptional counseling Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-04-01 Murat Cagan, Hanife Guler Donmez, Erdem Fadiloglu, Mehmet Sinan Beksac
This study focused on the link between skin disorders and Methylenetetrahydrofolate reductase (MTHFR) polymorphisms.Study cases were taken from a pre-conceptional care program where patients with p...
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A short-term economic evaluation of early insulin therapy compared to oral anti-diabetic drugs in order to reduce the major adverse events in type 2 diabetes patients in Iran Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-27 Ramin Heshmat, Ali Darvishi, Ramin Abdi Dezfouli, Adeleh Nikkhah, Ramin Radmanesh, Elham Moslemi
While there are some recommendations about early insulin therapy in newly diagnosed Type 2 Diabetes Mellitus (T2DM) patients, there is not sufficient evidence on this strategy’s cost-effectiveness....
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Assessment of algorithms for identifying patients with triple-class refractory multiple myeloma using real-world data Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-25 Liliya Sinyavskaya, Aster Meche, Ariane Faucher, Patrick Hlavacek, Sarasa MA Johnson, Marco DiBonaventura, Francis Vekeman, Jinma Ren, Alex Schepart
Objective: Patients with triple-class refractory (TCR) multiple myeloma (MM) have limited treatment options and poor prognoses. This high unmet need has prompted the development of new therapies al...
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Methamphetamine intoxication and suicidal ideation/behavior in the Emergency Department Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-21 Huseyin Bayazit, Regina Baronia, Sarah M. Wakefield
This study investigates the association between Methamphetamine (MA) intoxication and suicidal ideation/behavior in patients presenting to emergency departments. Amidst rising MA use and co-use wit...
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Sex differences in clinical features, utilization of oral anticoagulant agents, and one-year outcome in Middle Eastern patients with atrial fibrillation Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-20 Nasr Alrabadi, Mohammed Al-Nusair, Razan Haddad, Basheer S. Alghizzawi, Nashmi Al-Nusair, Saleh Alhaj Mohammad, Saif M. Shteiwi, Maryam K. El-zubi, Zaid Marie, Ayham Alnsour, Mohamad Jarrah, Karem H. Alzoubi, Ayman Hammoudeh
Studies have revealed that sex can predict differences in multiple aspects of atrial fibrillation (AF). These differences are underreported in the Middle East. This study aims to describe sex-speci...
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Diabetes: a review of its pathophysiology, and advanced methods of mitigation Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-21 Sarika Gupta, Nitin Sharma, Sandeep Arora, Saurabh Verma
Diabetes mellitus (DM) is a long-lasting metabolic non-communicable disease often characterized by an increase in the level of glucose in the blood or hyperglycemia. Approximately, 415 million peop...
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The use of routinely collected healthcare records for outcome assessment in clinical trials: a UK perspective Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-21 Abilash Sathyanarayana
The use of routinely collected electronic healthcare records (EHR) for outcome assessment in clinical trials has been described as a ‘disruptive’ new technique more than a decade ago. Despite this ...
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Preferences of healthcare providers in Switzerland for attributes of pediatric hexavalent vaccines: a discrete-choice experiment Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-19 Salome Samant, Susanne Oberle, Tomas Marcek, Christine Poulos, Phani Chintakayala, Edith Langevin, Tanaz Petigara, Marco Boeri
To understand the preferences of healthcare providers (HCPs) in Switzerland for pediatric hexavalent vaccine attributes.A discrete-choice experiment included a series of choices between 2 hypotheti...
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Clinical validation of a fast-acting acetaminophen: a randomized, active and placebo controlled dental pain study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-20 Andrew Myers, Todd Bertoch, Paul Zhang, Stephen A Cooper
Objectives: To address the need for faster pain relief of over-the-counter (OTC) analgesic users, a novel drug delivery technology was developed to achieve faster absorption of orally administered ...
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Addressing hepatitis delta in primary care practices in the US: a narrative review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-15 Tatyana Kushner, Richard R. Andrews
Infection with the hepatitis delta virus (HDV), a unique RNA virus that requires hepatitis B virus (HBV) antigens for its assembly, replication, and transmission, causes severe viral hepatitis. Com...
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Evaluation of effect of brief-intensive cognitive behavior therapy on symptoms severity in relation with catastrophic cognition in patients with panic disorder: a randomized controlled trial Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-15 Rasoul Sabri Piro, Perjan Hashim Taha
Due to a dearth of evidence, we examined the effectiveness of brief-intensive CBT on symptom severity and catastrophic cognition in patients with panic disorder (PD).In this randomized controlled t...
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Antidepressant medications have evolved in terms of speed of onset of efficacy: How can we best measure antidepressant treatment response? Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-15 Jan A. Sedway, Mark G. A. Opler, Leslie Citrome
Published in Current Medical Research and Opinion (Vol. 40, No. 4, 2024)
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Treatment patterns and outcomes among adults with immune thrombocytopenia receiving pharmaceutical second-line therapies: a retrospective cohort study using administrative claims data Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-11 Yi Liang, Karen Rascati, Jamie C. Barner, Kenneth A. Lawson, Radhika Nair
Objectives: To describe and compare real-world treatment patterns and clinical outcomes among individuals with immune thrombocytopenia (ITP) receiving second-line therapies (rituximab, romiplostim,...
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Model-based simulation of glycaemic effect and body weight loss when switching from semaglutide or dulaglutide to once weekly tirzepatide Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-12 Shweta Urva, Joshua A. Levine, Karen Schneck, Cheng Cai Tang
To evaluate the efficacy endpoints of HbA1c and body weight loss after switching from the GLP-1 receptor agonists, semaglutide or dulaglutide, to treatment with the GIP/GLP-1 receptor agonist (RA) ...
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Extemporaneous combination therapy with nebivolol/amlodipine for the treatment of hypertension: a real-world evidence study in Europe Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-08 Giovambattista Desideri, Riccardo Cipelli, Valeria Pegoraro, Claudio Ripellino, Marco Miroddi, Suada Meto, Mario Gori, Paolo Fabrizzi
Objective: The investigation of the real-world use of the extemporaneous combination of nebivolol and amlodipine (NA-EXC) in adult patients diagnosed with hypertension in Europe.Methods: Retrospect...
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Personality dimensions and treatment adherence among glaucoma patients: the role of self-transcendence Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-08 Dina Lešin Gaćina, Darko Marčinko, Tomislav Kuzman, Ivan Škegro, Sania Vidas Pauk, Bernarda Škegro, Martina Tomić, Tomislav Bulum, Sonja Jandroković
Cloninger’s psychobiosocial model of personality proposes that consistent patterns of health behavior are determined by the complex interaction of different neurobiological processes of the patient...
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Is dependent cannabis use in adult hospitalizations with inflammatory bowel disease associated with major adverse cardiovascular and cerebrovascular events? Insights from National Inpatient Sample Analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-08 Vamsikalyan Borra, Nithya Borra, Gayatri Bondi, Sai Goutham R. Yartha, Naga Vamsikrishna Machineni, Charu Agarwal, Karthikeya Ramasahayam, Purnachandra Rao Kuchipudi, Sravya R. Mundla, Prerna Bansal, Sagar A. Bathija, Ikechukwu R. Ogbu, Rupak Desai
Inflammatory bowel disease (IBD) and dependent cannabis use or cannabis use disorder (CUD+) are independent risk factors for cardiovascular diseases. Usage of cannabis for pain increased in IBD pat...
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Humanistic burden of mucopolysaccharidoses: a systematic literature review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-08 Joyce Wai-Yin Li, Kevin Yan, Chakrapani Balijepalli, Eric Druyts
To systematically review the literature and summarize the health-related quality-of-life (HRQoL) of patients undergoing treatment for mucopolysaccharidoses (MPS), a rare, hereditary lysosomal stora...
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Prevalence of comorbidities with the potential to increase the risk of nonadherence to topical ocular hypotensive medication in patients with open-angle glaucoma Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-07 M. Francesca Cordeiro, Philippe Denis, Carlo Astarita, Jonathan Belsey, Marcos Rivas, Julián García-Feijoo
To evaluate the prevalence of comorbidities that may limit or prevent adherence to topical ocular hypotensive therapy in patients with open-angle glaucoma (OAG).The UK Clinical Practice Research Da...
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Patient characteristics, treatment patterns, healthcare resource utilization, and costs among patients diagnosed with neurofibromatosis type 1 with and without plexiform neurofibromas in Japan Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-07 Yuichi Yoshida, Keiichi Tozawa, Ryo Koto, Chikako Iwao, YongJin Kim, Lu Ban, Volkan Barut
The objectives of this study were to retrospectively investigate the patient characteristics, treatment patterns, healthcare resource utilization (HCRU), and healthcare costs related to management ...
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Real-world diagnostic landscape and incidence of pulmonary hypertension in adult congenital heart disease patients using administrative claims data in Japan Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-06 Tomoko Ishizu, Yasuhiro Hayashi, Natsuko Tokushige, Junichi Omura
Although pulmonary hypertension (PH) and Eisenmenger’s syndrome (ES) are common complications in adult congenital heart disease (ACHD), the frequency of diagnostic tests and the incidence of PH/ES ...
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Real-world evidence of Pressure-Enabled Drug Delivery for trans-arterial chemoembolization and radioembolization among patients with hepatocellular carcinoma and liver metastases Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-05 Keziah Cook, Deepshekhar Gupta, Yunjuan Liu, Chris Miller-Rosales, Fangzhou Wei, Edward Tuttle, Steven C. Katz, Richard Marshak, Alexander Y. Kim
Pressure-Enabled Drug Delivery (PEDD), a method using pressure to advance catheter-delivered drug distribution, can improve treatment for hepatocellular carcinoma (HCC) and liver metastases, but re...
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Combining biomarkers of BNIP3 L, S100B, NSE, and accessible measures to predict sepsis-associated encephalopathy: a prospective observational study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-05 Nannan Zhang, Keliang Xie, Fei Yang, Yunying Wang, Xinhao Yang, Lina Zhao
Accurate identification of delirium in sepsis patients is crucial for guiding clinical diagnosis and treatment. However, there are no accurate biomarkers and indicators at present. We aimed to iden...
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Association of echocardiography-related parameters with the prognosis of decompensated cirrhosis: a retrospective cohort study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-04 Weiwei Wang, Liyan Dong, Yue Gao, Fangbo Gao, Zhongchao Wang, Min Ding, Chunru Gu, Zhe Li, Yue Yin, Menghua Zhu, Hongxin Chen, Hongyu Li, Xingshun Qi
Cardiac morphology and function, which are conventionally evaluated by echocardiography, are often abnormal in decompensated cirrhosis. We aimed to evaluate the association of echocardiography-rela...
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Good Publication Practice (GPP) guidelines for company-sponsored biomedical research from the point of view of the diverse authors involved in its publication Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-04 Leslie Citrome, Lisa M. DeTora, Dikran Toroser, Angela Sykes, Trevor Lane, Eline Hanekamp, Laura Dormer, Faith DiBiasi, Lise Baltzer
Published in Current Medical Research and Opinion (Vol. 40, No. 4, 2024)
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Measuring the impact of scientific publications and publication extenders: examples of novel approaches Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-29 Avishek Pal, Wesley Portegies, Jennifer Schwinn, Michael Taylor, Tomas J. Rees, Sarah Thomas, Kim Brown, Gareth Morrell, Josh Nicholson, Brian Falcone, Renu Juneja
Different stakeholders, such as authors, research institutions, and healthcare professionals (HCPs) may determine the impact of peer-reviewed publications in different ways. Commonly-used measures ...
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Understanding the impact of non-alcoholic steatohepatitis with metabolic comorbidities on adults: a real-world qualitative study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-29 Shraddha Shinde, Natalie Taylor, Chanadda Chinthammit, Rozanne Wilson, Somali Misra Burgess, Jiat-Ling Poon
Limited real-world evidence exists to better understand the patient experience of living with symptoms and impacts of non-alcoholic steatohepatitis (NASH). This study aimed to (1) describe patient-...
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Association between pan-immune inflammatory value and ulcerative colitis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-26 Aslıhan Mete Yıldırım, Oğuzhan Yıldırım
Ulcerative colitis is a chronic idiopathic disease that causes inflammation of the colon and rectum, progressing with relapses and remissions. Systemic inflammatory index (SII) and pan-immune infla...
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Role of the brain-sparing effect on retinopathy of prematurity in newborns with fetal growth restriction Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-23 Osman Ahmet Polat, Mehmet Mete Kirlangic, Erdem Sahin, Yusuf Madendag, Cem Evereklioglu, Fatih Horozoglu, Cagatay Karaca
This study aimed to investigate the role of the brain-sparing effect (BSE) on retinopathy of prematurity (ROP) in fetal growth restriction (FGR).In this retrospective study, 127 pregnant women were...
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Treatment patterns of galcanezumab versus standard of care preventive migraine medications over 24 months: a US retrospective claims study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-22 Oralee J. Varnado, Michelle Vu, Erin K. Buysman, Gilwan Kim, Gayle Allenback, Margaret Hoyt, Helen Trenz, Feng Cao, Lars Viktrup
To describe long-term (24-month) treatment patterns of patients initiating galcanezumab versus standard of care (SOC) preventive migraine treatments including anticonvulsants, beta-blockers, antide...
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Short-term COVID-19 vaccine adverse effects among adults in Ekiti State, Nigeria Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-22 Bolade Folasade Dele-Ojo, Adedapo Adesokan, Joseph Olusesan Fadare, Paul Oladapo Ajayi, Taiwo Hussean Raimi, Samuel Ayokunle Dada, Owolabi Dele Ojo, James Ayodele Ogunmodede, Tope Michael Ipinnimo, Olumuyiwa Elijah Ariyo, Brian Godman
The safety of the COVID-19 vaccines has been a topic of concern globally. This issue of safety is associated with vaccine hesitancy due to concerns about the adverse effects of the vaccines. Conseq...
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Goal setting and goal attainment in patients with major depressive disorder: a narrative review on shared decision making in clinical practice Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-19 David S. Baldwin, Michael Adair, Arun Micheelsen, Daniel Oudin Åstrøm, Elin H. Reines
Narrative review of the processes of goal setting and goal attainment scaling, as practical approaches to operationalizing and implementing the principles of shared decision making (SDM) in the rou...
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Preferences for different treatment options among people living with acromegaly in the US Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-15 Jill Sisco, Mattias Furumalm, Cecilie Yssing, Anna Okkels, Stojan Zavisic
Acromegaly is a rare hormonal disorder that results in enlargement of the face, hands and feet. It is associated with comorbidities, increased mortality, reduced quality of life and economic burden...
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Publishing clinical trial results in plain language: a clash of ethical principles? Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-14 Avishek Pal, Ingrid Klingmann, Tenzin Wangmo, Bernice Elger
Plain language resources (PLR) are lay summaries of clinical trial results or plain language summaries of publications, in digital/visual/language formats. They aim to provide accurate information ...
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CercaTest Red, a novel urine-based point-of-care test for the detection of preeclampsia Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-14 Xuemin Liu, Jun Xu, Chao Liu, Xingmin Li
Preeclampsia (PE) poses a serious threat to the health of the pregnant woman and her developing fetus due to the difficulty in diagnosing the condition. The disease can develop and worsen suddenly ...
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Effectiveness and safety of anticoagulants among patients with venous thromboembolism and active cancer who also had prior bleed or prior renal disease Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-13 Alexander T. Cohen, Virginia Noxon, Amol D. Dhamane, Shrushti Shah, Dionne M. Hines, Tamuno Alfred, José Chaves, Xuemei Luo
Patients with active cancer and venous thromboembolism (VTE) have elevated risk of recurrent VTE (rVTE) and major bleeding (MB). The risk is even higher within those with a prior bleeding event or ...
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Audit of adherence to international guidelines (IDSA) in the treatment of infectious meningitis in pediatric patients in Jordan Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-13 Dina Mohialdin, Rana Abu-Farha, Rama ALkhawaldeh, Mohammed Zawiah, Khawla Abu Hammour
This study aims to audit the adherence of Jordanian medical care staff to the guidelines provided by the Infectious Disease Society of America (IDSA) for managing pediatric patients admitted with s...
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The role of lactate-to-albumin ratio to predict 30-day risk of death in patients with sepsis in the emergency department: a decision tree analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-12 Gianni Turcato, Arian Zaboli, Serena Sibilio, Marta Parodi, Michael Mian, Francesco Brigo
Accurately estimating the prognosis of septic patients on arrival in the emergency department (ED) is clinically challenging. The lactate-to-albumin ratio (LAR) has recently been proposed to improv...
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Successful treatment of severe alcohol withdrawal delirium with very high-dose diazepam (260–480 mg) administration Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-12 Şükrü Alperen Korkmaz, Ebru Aldemir, Demet Güleç Öyekçin
Alcohol withdrawal delirium, commonly known as “delirium tremens (DT)”, is the most severe clinical condition of alcohol withdrawal syndrome (AWS). Symptoms of DT include changes in consciousness a...
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Factors and economic burden of non-severe hypoglycemia among insulin-treated type 2 diabetes patients: a cross-sectional study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-12 Natapong Kosachunhanun, Danil Wongsa, Unchalee Permsuwan
This cross-sectional survey was performed to assess the prevalence, factors, and economic burden of non-severe hypoglycemia among insulin-treated type 2 diabetes (T2D) patients in northern Thailand...
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Risk prediction models of mortality after hip fracture surgery in older individuals: a systematic review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-07 Ying Sun, Yanhui Liu, Yaning Zhu, Ruzhen Luo, Yiwei Luo, Shanshan Wang, Zihang Feng
This study aimed to critically assess existing risk prediction models for postoperative mortality in older individuals with hip fractures, with the objective of offering substantive insights for th...
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Between human and AI: assessing the reliability of AI text detection tools Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-02 Valentina Bellini, Federico Semeraro, Jonathan Montomoli, Marco Cascella, Elena Bignami
Large language models (LLMs) such as ChatGPT-4 have raised critical questions regarding their distinguishability from human-generated content. In this research, we evaluated the effectiveness of on...
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Patient journey of civilian adults diagnosed with posttraumatic stress disorder—A chart review study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-30 Lori L. Davis, Annette Urganus, Patrick Gagnon-Sanschagrin, Jessica Maitland, Jerome Bedard, Remi Bellefleur, Martin Cloutier, Annie Guérin, Jyoti Aggarwal
To assess the journey of individuals from experiencing a traumatic event through onset of symptoms, diagnosis, and treatment of posttraumatic stress disorder (PTSD).Patient- and psychiatrist-level ...
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Biofilm-producing antibiotic-resistant bacteria in Indian patients: a comprehensive review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-27 Susmita Datta, Soma Nag, Dijendra Nath Roy
For the past few years, microbial biofilms have been emerging as a significant threat to the modern healthcare system, and their prevalence and antibiotic resistance threat gradually increase daily...
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The power of language: how to bridge the gap between healthcare research and patients – a scoping review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Sally-Anne Dews, Rachel Daley, Akhil Bansal, Jennifer Preston, Natalie Bohm
The value of patient involvement to the design, conduct, and outcomes of healthcare research is increasingly being recognized. Patient involvement also provides greater patient accessibility and co...
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Analgesic onset and efficacy of a fast-acting formulation of acetaminophen in a postoperative dental impaction pain model Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Andrew Myers, Cathy Gelotte, Annette Zuckerman, Brenda Zimmerman, Ami Shenoy, Dan Qi, Stephen A. Cooper
Speed of onset can be critical to an analgesic’s efficacy treating acute pain. To enhance onset, a new oral acetaminophen formulation intended to be fast acting was developed. Two studies evaluated...
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Diabetes management, dietary supplements use and the effect of coronavirus pandemic on diabetes patients in Serbia: a cross-sectional study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Milana Vuković, Jelena Jovičić Bata, Nemanja Todorović, Gorana Puača, Dunja Vesković, Jelena Čanji Panić, Tihomir Dugandžija, Mladena Lalić-Popović
Diabetes mellitus (DM) is a significant public health challenge in Serbia, mirroring the situation in other European middle-income countries. The aims of this study were to examine the disease-rela...
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What to expect in 2024: important health economics and outcomes research (HEOR) trends Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Ivo Abraham, Mickael Hiligsmann, Kenneth K. C. Lee, Leslie Citrome, Giorgio L. Colombo, Mike Gregg
Published in Current Medical Research and Opinion (Vol. 40, No. 2, 2024)
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Associations of serum uric acid levels and anthropometric parameters with non-alcoholic fatty liver disease in healthy individuals: innovative insights from a cross-sectional study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Ahmet Aydin, Sabin Goktas Aydin
Non-alcoholic fatty liver disease (NAFLD is a spectrum of liver disease with a rising prevalence, ranging from simple steatosis to steatohepatitis and cirrhosis, where a significant minority face p...