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Portable robots for upper-limb rehabilitation after stroke: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-04-19 Kevin C. Tseng, Le Wang, Chunkai Hsieh, Alice M. Wong
Robot-assisted upper-limb rehabilitation has been studied for many years, with many randomised controlled trials (RCTs) investigating the effects of robotic-assisted training on affected limbs. The...
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Moral decision-making at night and the impact of night work with blue-enriched white light or warm white light: a counterbalanced crossover study Ann. Med. (IF 4.4) Pub Date : 2024-04-18 Erlend Sunde, Anette Harris, Olav Kjellevold Olsen, Ståle Pallesen
Cognitive function, including moral decision-making abilities, can be impaired by sleep loss. Blue-enriched light interventions have been shown to ameliorate cognitive impairment during night work....
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Cohabiting with ulcerative colitis patients decreases differences of gut microbiome between healthy individuals and the patients Ann. Med. (IF 4.4) Pub Date : 2024-04-13 Chen Li, Xiaoyan Guo, Yan He, Jing Wang, Jianyu Hao, Xinjuan Liu
Background: Ulcerative colitis (UC), which is characterized by chronic relapsing inflammation of the colon, results from a complex interaction of factors involving the host, environment, and microb...
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A systematic review and network meta-analysis on the effectiveness of exercise-based interventions for reducing the injury incidence in youth team-sport players. Part 2: an analysis by movement patterns Ann. Med. (IF 4.4) Pub Date : 2024-04-13 Francisco Ayala, Francisco Javier Robles-Palazón, Desirée Blázquez-Rincón, Alejandro López-Valenciano, José Antonio López-López, Mark De Ste Croix
The objectives of this network meta-analysis were: (a) to estimate and compare the pooled effects of some injury prevention programs (IPPs) whose exercise-based components were categorized using a ...
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Myeloid neoplasms post cytotoxic therapy: epidemiology, pathogenesis outcomes, prognostic factors, and treatment options Ann. Med. (IF 4.4) Pub Date : 2024-04-12 Jing Ma, Yafei Wang
Myeloid neoplasms post cytotoxic therapy (MN-pCT) are a category includes AML, MDS, and MDS/MPN arising in patients exposed to cytotoxic (DNA-damaging) therapy for an unrelated condition in 2022 ve...
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Outpatient management of essential hypertension: a review based on the latest clinical guidelines Ann. Med. (IF 4.4) Pub Date : 2024-04-11 Areesha Moiz, Tetiana Zolotarova, Mark J. Eisenberg
Background: Essential hypertension, a prevalent cardiovascular condition, poses a significant health burden worldwide. Based on the latest American clinical guidelines, half of adults in the United...
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Survival and causes of death in patients with alpha and beta-thalassemia in Northern Thailand Ann. Med. (IF 4.4) Pub Date : 2024-04-11 Adisak Tantiworawit, Thansita Kamolsripat, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Kanda Fanhchaksai, Pimlak Charoenkwan
Thalassemia is the most prevalent hereditary anaemia worldwide. Severe forms of thalassemia can lead to reduced life expectancy due to disease-related complications.To investigate the survival of t...
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Co-creation of injury prevention measures for competitive adolescent distance runners: knowledge, behavior, and needs of athletes and coaches enrolled on England Athletics’ Youth Talent Programme Ann. Med. (IF 4.4) Pub Date : 2024-04-10 Robert H. Mann, Bryan C. Clift, Jo Day, Alan R. Barker
This study assessed the knowledge, behavior, and needs of competitive adolescent (16–18 years) distance runners and distance running coaches enrolled as part of England Athletics’ Youth Talent Prog...
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Circulating plasma cells as a predictive biomarker in Multiple myeloma: an updated systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-04-10 Qun Li, Lisha Ai, Liping Zuo, Junying Li, Fei Zhao, Aoshuang Xu, Bo Zhang, Li Cai, Yu Hu, Chunyan Sun
Circulating plasma cells (CPCs) are defined by the presence of peripheral blood clonal plasma cells, which would contribute to the progression and dissemination of multiple myeloma (MM). An increas...
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Anabolic-androgenic steroids are linked to depression and anxiety in male bodybuilders: the hidden psychogenic side of anabolic androgenic steroids Ann. Med. (IF 4.4) Pub Date : 2024-04-08 Baris Karagun, Selin Altug
The prevalence of anabolic-androgenic steroids (AAS) use is on the rise among athletes and bodybuilders worldwide. In addition to the well-documented adverse effects on hepatic, renal, and reproduc...
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Value of modified qSOFA, glucose and lactate in predicting prognosis in children with sepsis in the PICU Ann. Med. (IF 4.4) Pub Date : 2024-04-08 Wanyu Jia, Xue Zhang, Ruiyang Sun, Peng Li, Daobin Wang, Xue Gu, Chunlan Song
The purpose was to investigate how well age-adjusted modified quick Sequential Organ Failure Assessment (qSOFA) scores paired with blood glucose and lactate levels predict the outcomes of septicemi...
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Identification of pathogen composition in a Chinese population with iatrogenic and native vertebral osteomyelitis by using mNGS Ann. Med. (IF 4.4) Pub Date : 2024-04-08 Qile Gao, Qianfei Liu, Guang Zhang, Yingqing Lu, Yanbing Li, Mingxing Tang, Shaohua Liu, Hongqi Zhang, Xiaojiang Hu
Early antimicrobial therapy is crucial regarding the prognosis of vertebral osteomyelitis, but early pathogen diagnosis remains challenging.In this study, we aimed to differentiate the types of pat...
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Perception, confidence, and willingness to respond to in-flight medical emergencies among medical students: a cross sectional study Ann. Med. (IF 4.4) Pub Date : 2024-04-08 Majed Alnabulsi, Ehab Abdelhalim Abo Ali, Mohammad Hassan Alsharif, Najla’a Fathi Filfilan, Sahar Hamed Fadda
In-flight medical emergencies (IMEs) are expected to increase as air travel normalized in the post-COVID-19 era. However, few studies have examined health professions students’ preparedness to resp...
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Multifaceted associations between walking performance, physical fitness, extremity function, health status, and depression in individuals with COPD Ann. Med. (IF 4.4) Pub Date : 2024-04-08 Monira I. Aldhahi, Baian A. Baattaiah, Mutasim D. Alharbi, Mansour Alotaibi, Rakan Nazer, Ali Albarrati
Chronic obstructive pulmonary disease (COPD) can precipitate a deterioration of an individual’s physical performance and overall health. Evidence suggests that, along with pulmonary functions, seve...
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T266M variants of ANGPTL4 improve lipid metabolism by modifying their binding affinity to acetyl-CoA carboxylase in obstructive sleep apnea Ann. Med. (IF 4.4) Pub Date : 2024-04-04 Xinyi Li, Chenyang Li, Wenjun Xue, Zhicheng Wei, Hangdong Shen, Kejia Wu, Huaming Zhu, Huajun Xu, Xiaolin Wu, Hongliang Yi, Jian Guan, Shankai Yin
Angiopoietin-like protein 4 (ANGPTL4) is recognized as a crucial regulator in lipid metabolism. Acetyl-CoA carboxylases (ACACAs) play a role in the β-oxidation of fatty acids. Yet, the functions of...
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Anxiety and depression status in patients with idiopathic pulmonary fibrosis and outcomes of nintedanib treatment: an observational study Ann. Med. (IF 4.4) Pub Date : 2024-04-06 Xing He, Jiaqi Ji, Zongmin Pei, Zeli Luo, Siyu Fang, Xiaoqin Liu, Yan Lei, Haiying Yan, Lu Guo
Anxiety and depression are common comorbidities in idiopathic pulmonary fibrosis (IPF) that impair health-related quality of life. However, there is a lack of studies focusing on the mental disorde...
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Non-invasive prediction nomogram for predicting significant fibrosis in patients with metabolic-associated fatty liver disease: a cross-sectional study Ann. Med. (IF 4.4) Pub Date : 2024-04-04 Fan Zhang, Yan Han, Yonghua Mao, Guojun Zheng, Longgen Liu, Wenjian Li
This study aims to validate the efficacy of the conventional non-invasive score in predicting significant fibrosis in metabolic-associated fatty liver disease (MAFLD) and to develop a non-invasive ...
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Prognostic and clinicopathological value of systemic inflammation response index (SIRI) in patients with breast cancer: a meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-04-03 Sunhuan Zhang, Tongtong Cheng
Many studies have explored the value of the systemic inflammation response index (SIRI) in predicting the prognosis of patients with breast cancer (BC); however, their findings remain controversial...
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The role of payment sources in the continuation of rehabilitation therapy in tertiary hospitals for patients with traumatic spinal cord injury: a study in Southwest China Ann. Med. (IF 4.4) Pub Date : 2024-04-01 Lihua Jin, Yongqian Han, Juchuan Dong, Haonan Wang, Yifei Dong, Wenyuan Wang, Yongmei Li
Medical security support for rehabilitation therapy in China is different from that in other countries. We investigated whether the discharge plan to continue rehabilitation therapy in tertiary hos...
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A brief review of complex regional pain syndrome and current management Ann. Med. (IF 4.4) Pub Date : 2024-04-03 Alaa Abd-Elsayed, Cain W. Stark, Natasha Topoluk, Mir Isaamullah, Paul Uzodinma, Omar Viswanath, Michael J. Gyorfi, Osama Fattouh, Kevin C. Schlidt, Omar Dyara
Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition that, although exceedingly rare, carries a significant burden for the affected patient population. The complex and amb...
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The prevalence and risk factors of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-03-28 Hong-Fei Wang, Yan-Yun Wang, Zhi-Yu Li, Pei-Jie He, Shan Liu, Qiu-Shuang Li
Interstitial lung disease (ILD) is the most widespread and fatal pulmonary complication of rheumatoid arthritis (RA). Existing knowledge on the prevalence and risk factors of rheumatoid arthritis-a...
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Network analysis of smoking-related sleep characteristics in Chinese adults Ann. Med. (IF 4.4) Pub Date : 2024-03-25 Yuting Xie, Peiyuan Sun, Huang Huang, Jianjun Wu, Yue Ba, Guoyu Zhou, Fangfang Yu, Daming Zhang, Yaqun Zhang, Ranran Qie, Zhuolun Hu, Kaiyong Zou, Yawei Zhang
The associations between multiple sleep characteristics and smoking behavior are inconsistent, and it is unclear which sleep characteristics are most crucial for tobacco prevention. This study aime...
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The correlation between serum total bile acid and adverse perinatal outcomes in pregnant women with intrahepatic cholestasis of pregnancy (ICP) and non-ICP hypercholanemia of pregnancy Ann. Med. (IF 4.4) Pub Date : 2024-03-21 Peizhen Zhang, Zhangmin Tan, Chuo Li, Zhenyan Han, Jin Zhou, Yuzhu Yin
The association between excessive serum total bile acid (TBA) and adverse perinatal outcomes in individuals with non-intrahepatic cholestasis of pregnancy (non-ICP) hypercholanemia has not been det...
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Association between the haemoglobin glycation index (HGI) and clinical outcomes in patients with acute decompensated heart failure Ann. Med. (IF 4.4) Pub Date : 2024-03-21 Weimeng Cheng, Rong Huang, Yue Pu, Tianyue Li, Xue Bao, Jianzhou Chen, Guannan Li, Han Wu, Zhonghai Wei
A growing number of studies show that people with similar blood glucose levels have different levels of glycosylated haemoglobin (HbA1c), and relying only on HbA1c may lead to clinical decision-mak...
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A differential diagnosis method for systemic CAEBV and the prospect of EBV-related immune cell markers via flow cytometry Ann. Med. (IF 4.4) Pub Date : 2024-03-19 Jie Jin, Xia Mao, Donghua Zhang
Chronic active Epstein-Barr virus (CAEBV) infection of the T-cell or Natural killer (NK)-cell type, systemic form (systemic CAEBV or sCAEBV) was defined by the WHO in 2017 as an EBV-related lymphop...
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Development of a nomogram for predicting myopia risk among school-age children: a case-control study Ann. Med. (IF 4.4) Pub Date : 2024-03-20 Jingfeng Mu, Haoxi Zhong, Mingjie Jiang, Jiantao Wang, Shaochong Zhang
To analyze the factors influencing myopia and construct a nomogram to forecast the risk of myopia among school-age children, providing a reference for identifying high-risk groups to aid prevention...
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Steatotic liver disease among lean and non-lean individuals in Southern Lao PDR: a cross-sectional study of risk factors Ann. Med. (IF 4.4) Pub Date : 2024-03-19 Anousin Homsana, Phonesavanh Southisavath, Kerstin Kling, Jan Hattendorf, Savina Vorasane, Daniel Henry Paris, Somphou Sayasone, Peter Odermatt, Nicole Probst-Hensch
Steatotic liver disease (SLD) prevalence is rising worldwide, linked to insulin resistance and obesity. SLD prevalence can surpass 10% even among those with normal weight. In Lao People’s Democrati...
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Nomogram for predicting postoperative ileus after radical cystectomy and urinary diversion: a retrospective single-center study Ann. Med. (IF 4.4) Pub Date : 2024-03-18 Xiaoyu Sun, Chang Liu, Changwen Zhang, Zhihong Zhang
To predict the incidence of postoperative ileus in bladder cancer patients after radical cystectomy.We retrospectively analyzed the perioperative data of 452 bladder cancer patients who underwent r...
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A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography Ann. Med. (IF 4.4) Pub Date : 2024-03-19 Zhengxi Zhang, Jianbo Mao, Jimeng Lao, Xinyi Deng, Yuyan Fang, Nuo Chen, Chenyi Liu, Yiqi Chen, Lijun Shen
To evaluate the characteristics and prognoses of idiopathic macular epiretinal membrane (iERM) using a classification based on the foveal avascular zone (FAZ) area.IERMs were classified into four s...
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Research progress on the mechanism of common inflammatory pathways in the pathogenesis and development of lymphoma Ann. Med. (IF 4.4) Pub Date : 2024-03-15 Aorong Shi, Fen Yun, Lin Shi, Xia Liu, Yongfeng Jia
In recent years, the incidence and mortality rates of lymphoma have gradually increased worldwide. Tumorigenesis and drug resistance are closely related to intracellular inflammatory pathways in ly...
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Exploring the molecular mechanisms of asthma across multiple datasets Ann. Med. (IF 4.4) Pub Date : 2024-03-15 Lianshan Guo, Enhao Huang, Tongting Wang, Yun Ling, Zhengzhao Li
Asthma, a prevalent chronic respiratory disorder, remains enigmatic, notwithstanding considerable advancements in our comprehension. Continuous efforts are crucial for discovering novel molecular t...
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Rapid cycle deliberate practice: application in forceps simulation training for gynecology and obstetrics residents Ann. Med. (IF 4.4) Pub Date : 2024-03-13 Xiaoxue Wang, Zixuan Song, Xueting Chen, Yangzi Zhou, Yingze Lou, Tong Liu, Dandan Zhang
Rapid Cycle Deliberate Practice (RCDP) has gained prominence in recent years as an innovative teaching method in simulation-based training for adult and pediatric emergency medical skills. However,...
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G-CSF + plerixafor versus G-CSF alone mobilized hematopoietic stem cells in patients with multiple myeloma and lymphoma: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-03-12 Yuyao Li, Xia Qiu, Yupeng Lei, Ruixi Zhou
The combination of granulocyte-colony stimulating factor (G-CSF) and plerixafor is one of the approaches for hematopoietic stem cell mobilization in patients with multiple myeloma (MM), non-Hodgkin...
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Acceptability of two mobile applications to support cross-sectoral, person-centred and empowering stroke rehabilitation – a process evaluation Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Mille Nabsen Marwaa, Susanne Guidetti, Charlotte Ytterberg, Hanne Kaae Kristensen
To evaluate the acceptability of two co-designed mobile applications Mit Sygehus [a knowledge-based solution] and Genoptræn.dk [a self-training solution] to support a cross-sectoral, person-centred...
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Impact of physical activity on preeclampsia and angiogenic markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Noora Jaatinen, Eeva Ekholm, FINNPEC, Hannele Laivuori, Tiina Jääskeläinen
Effect of physical activity in pregnancy on preeclampsia (PE) and angiogenic markers is not well understood. We studied the association of physical activity and PE in a case-control setting and ass...
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A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Moh Heri Kurniawan, Hanny Handiyani, Tuti Nuraini, Rr Tutik Sri Hariyati, Sutrisno Sutrisno
Utilizing artificial intelligence (AI) in chatbots, especially for chronic diseases, has become increasingly prevalent. These AI-powered chatbots serve as crucial tools for enhancing patient commun...
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Efficacy of the COVID-19 vaccination in patients with asymptomatic or mild illness during the Omicron epidemic in Guangzhou: a multi-centre retrospective cohort study Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Yuanda Xu, Xuetao Kong, Weiqing Huang, Zijing Liang, Jinkun Huang, Yimin Li, Nuofu Zhang, Dan Liu, Wenwei Guo, Jiang Mei
Despite the widespread administration of coronavirus disease 2019 (COVID-19) vaccines, the impact on patients with asymptomatic to mild illness remains unclear. Here, we aimed to assess the efficac...
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The psychosocial impact of eye-gaze assistive technology on everyday life of children and adults Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Maria Andreassen, Maria Borgestig, Helena Hemmingsson
This study investigates the psychosocial impact of eye-gaze assistive technology (EGAT) in both children and adults with long-term experience using eye-gaze assistive technology in everyday life, a...
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Knowledge, experiences, and perceptions of medications for opioid use disorder among Black Kentuckians Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Paris B. Wheeler, Brittany Miller-Roenigk, Jasmine Jester, Danelle Stevens-Watkins
Opioid overdoses have continued to increase at higher rates among Black Americans compared to people from other racial groups. Despite demonstrated effectiveness of MOUD in reducing risk of opioid ...
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A comprehensive evaluation of risk factors for mortality, infection and colonization associated with CRGNB in adult solid organ transplant recipients: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Siyu Gao, Xiaoli Huang, Xiaolin Zhou, Xiangcheng Dai, Jing Han, Yandong Chen, Hongliang Qiao, Yi Li, Yifan Zhou, Ting Wang, Huiqing He, Qiang Liu, Shenjie Tang
The burden of carbapenem-resistant gram-negative bacteria (CRGNB) among solid organ transplant (SOT) recipients has not been systematically explored. Here, we discern the risk factors associated wi...
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Tenecteplase versus alteplase for the treatment of acute ischemic stroke: a meta-analysis of randomized controlled trials Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Jian Huang, Hui Zheng, Xianfeng Zhu, Kai Zhang, Xiaofeng Ping
Tenecteplase, a modified variant of alteplase with greater fibrin specificity and longer plasma half-life, may have better efficacy and safety than alteplase in patients with acute ischemic stroke ...
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Gastrin-releasing peptide receptor (GRPR) as a novel biomarker and therapeutic target in prostate cancer Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Honghu Zhang, Lin Qi, Yi Cai, Xiaomei Gao
Aim: This comprehensive review aims to explore the potential applications of Gastrin-releasing peptide receptor (GRPR) in the diagnosis and treatment of prostate cancer. Additionally, the study inv...
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Insomnia is related to long-term atrial fibrillation recurrence following radiofrequency ablation Ann. Med. (IF 4.4) Pub Date : 2024-02-29 Rui-bin Li, Ji-dong Zhang, Xiao-ran Cui, Wei Cui
Atrial fibrillation (AF), the most common cardiac arrhythmia, presents significant health challenges, and the intricate connection between insomnia and AF has garnered substantial attention. This c...
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Advanced Parkinson’s disease treatment patterns in Italy: an observational study interim analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-21 Fabrizio Stocchi, Paolo Barone, Roberto Ceravolo, Maria Francesca De Pandis, Leonardo Lopiano, Nicola Modugno, Alessandro Padovani, Manuela Pilleri, Alessandro Tessitore, Mario Zappia
Oral levodopa remains the mainstay of treatment for Parkinson’s disease (PD). However, as PD progresses, response to treatment may fluctuate. Managing fluctuations can be demanding for clinicians a...
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Development and initial testing of mindful journey: a digital mindfulness-based intervention for promoting recovery from Substance use disorder Ann. Med. (IF 4.4) Pub Date : 2024-02-21 Corey R. Roos, Brian Kiluk, Kathleen M. Carroll, Jonathan B. Bricker, Chung Jung Mun, Margarita Sala, Megan Kirouac, Elena Stein, Maya John, Robert Palmer, Andrew DeBenedictis, Jena Frisbie, Angela M. Haeny, Declan Barry, Lisa M. Fucito, Sarah Bowen, Katie Witkiewitz, Hedy Kober
There is a great unmet need for accessible adjunctive interventions to promote long-term recovery from substance use disorder (SUD). This study aimed to iteratively develop and test the initial fea...
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Associations of thyroid feedback quantile-based index with diabetes in euthyroid adults in the United States and China Ann. Med. (IF 4.4) Pub Date : 2024-02-21 Heng Wan, Genfeng Yu, Yajun He, Siyang Liu, Xingying Chen, Yuqi Jiang, Hualin Duan, Xu Lin, Lan Liu, Jie Shen
We aimed to investigate the associations between thyroid hormone sensitivity indices and diabetes in euthyroid adults in the United States and China.2296 euthyroid adults from the NHANES in the Uni...
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Tai Chi training as a primary care plan for the prevention and management of hypertension: an opinion and positioning article Ann. Med. (IF 4.4) Pub Date : 2024-02-19 Ting Zhang, Shuman Yang, Wei Liu, Qingping Bai, Song Gao
Hypertension is a prevalent chronic condition worldwide that can impact patients’ quality of life. Oral antihypertensive drugs are widely used to manage high blood pressure, primarily by regulating...
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Propyl gallate induces human pulmonary fibroblast cell death through the regulation of Bax and caspase-3 Ann. Med. (IF 4.4) Pub Date : 2024-02-19 Woo Hyun Park
Propyl gallate (PG) has been found to exert an inhibitory effect on the growth of different cell types, including lung cancer cells. However, little is known about the cytotoxicological effects of ...
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LASSO-derived model for the prediction of lean-non-alcoholic fatty liver disease in examinees attending a routine health check-up Ann. Med. (IF 4.4) Pub Date : 2024-02-16 Chiao-Lin Hsu, Pin-Chieh Wu, Fu-Zong Wu, Hsien-Chung Yu
Lean individuals with non-alcohol fatty liver disease (NAFLD) often have normal body size but abnormal visceral fat. Therefore, an alternative to body mass index should be considered for prediction...
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Tuberculosis (TB) treatment challenges in TB-diabetes comorbid patients: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Mahnoor Khattak, Anees ur Rehman, Tuba Muqaddas, Rabia Hussain, Muhammad Fawad Rasool, Zikria Saleem, Mesfer Safar Almalki, Samar Adel Alturkistani, Shuruq Zuhair Firash, Oseid Mohammed Alzahrani, Ammar Abdulraheem Bahauddin, Safa Almarzooky Abuhussain, Muath Fahmi Najjar, Hossameldeen Mahmoud Ali Elsabaa, Abdul Haseeb
The Directly Observed Treatment-Short Course (DOTS) Programme was implemented by WHO and includes a combination of four anti-tuberculosis (TB) drugs (isoniazid, pyrazinamide, ethambutol and rifampi...
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Analysis of airway structural parameters in Han Chinese adults: a prospective cross-sectional study Ann. Med. (IF 4.4) Pub Date : 2024-02-16 Yan Liu, Jun Teng, Jian Mei, Chao Chen, Qian-qian Xu, Cui Zhou, Kang-li Deng, Hong-wu Wang
Establishing reference ranges for central airway parameters and exploring their influencing factors in Han Chinese non-smoking adults.This prospective cross-sectional study was conducted on Han Chi...
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Clinical characteristics of complete responders versus non-complete responders to omalizumab, benralizumab and mepolizumab in patients with severe asthma: a long-term retrospective analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-16 Maria Basagaña, Carlos Martínez-Rivera, Clara Padró, Ignasi Garcia-Olivé, Mimar Martínez-Colls, Juan Navarro, Laura Pardo, Paula Cruz, Gloria Cardona Peitx, Lídia Carabias, Albert Roger, Jorge Abad, Antoni Rosell
Some patients with severe asthma may benefit from treatment with biologics, but evidence has been mostly collected from randomized controlled trials (RCTs), in which patients’ characteristics are d...
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Advances in targeted therapy of cholangiocarcinoma Ann. Med. (IF 4.4) Pub Date : 2024-02-15 Yuhang Li, Jianfeng Yu, Yujing Zhang, Chuang Peng, Yinghui Song, Sulai Liu
Cholangiocarcinoma (CCA) is a malignant tumor originating in the bile duct and its branching epithelium. Due to its high heterogeneity, there are no specific clinical indications at the early stage...
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A multicenter feasibility randomized controlled trial using a virtual reality application of pain neuroscience education for adults with chronic low back pain Ann. Med. (IF 4.4) Pub Date : 2024-02-14 Ryan McConnell, Elizabeth Lane, Grace Webb, Dana LaPeze, Hailey Grillo, Julie Fritz
Chronic low back pain (CLBP) is a highly prevalent condition among adults and is correlated to high levels of pain, high disability, and lower quality of life. Pain neuroscience education (PNE) hel...
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Efficacy of intraoperative systemic lidocaine on quality of recovery after laparoscopic colorectal surgery: a randomized controlled trial Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Wenjun Lin, Ying Yang, Yifen Zhuo, Chunlin Qiu, Yanhua Guo, Yusheng Yao
Many clinical trials have demonstrated the benefits of intraoperative systemic lidocaine administration in major abdominal surgeries. We tested the hypothesis that systemic lidocaine is associated ...
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Fibrillatory wave amplitude and thromboembolic risk in non-anticoagulated patients with atrial fibrillation Ann. Med. (IF 4.4) Pub Date : 2024-02-13 Arto Relander, Samuli Jaakkola, Hilla Virri, Eelis Niemelä, Tuija Vasankari, Ilpo Nuotio, K. E. Juhani Airaksinen, Tuomas Kiviniemi
The benefit of oral anticoagulation in atrial fibrillation (AF) is well established for patients at elevated stroke risk, but less clear for those at intermediate risk. We investigated whether anal...
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Dual role for microbial short-chain fatty acids in modifying SIV disease trajectory following anti-α4β7 antibody administration Ann. Med. (IF 4.4) Pub Date : 2024-02-14 Samuel D. Johnson, Nageswara Pilli, Jianshi Yu, Lindsey A. Knight, Maureen A. Kane, Siddappa N. Byrareddy
Human Immunodeficiency Virus (HIV)/Simian Immunodeficiency Virus (SIV) infection is associated with significant gut damage, similar to that observed in patients with inflammatory bowel disease (IBD...
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Associations of nirmatrelvir-ritonavir treatment with death and clinical improvement in hospitalized patients with COVID-19 during the Omicron wave in Beijing, China: a multicentre, retrospective cohort study Ann. Med. (IF 4.4) Pub Date : 2024-02-14 Xiaobo Han, Chenglong Li, Xin Yuan, Junchang Cui, Zhihai Han, Jiguang Meng, Weiguo Zhao, Fei Xie, Kaifei Wang, Yuhong Liu, Guoxin Muo, Na Xi, Mengli Zheng, Rentao Wang, Kun Xiao, Wei Chen, Junchen Xiong, Dahui Zhao, Xinxin Zhang, Xinjie Han, Haibo Cheng, Zhongkuo Yu, Yinghan Shi, Wuxiang Xie, Lixin Xie
The effectiveness of nirmatrelvir–ritonavir has mainly been shown in non-hospitalized patients with mild-to-moderate coronavirus disease 2019 (COVID-19). The real-world effectiveness of nirmatrelvi...
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The role of molecular imaging in detecting fibrosis in Crohn’s disease Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Ali S. Alyami, Yahia Madkhali, Naif A. Majrashi, Bandar Alwadani, Meaad Elbashir, Sarra Ali, Wael Ageeli, Hesham S. El-Bahkiry, Abdullah A. Althobity, Turkey Refaee
Fibrosis is a pathological process that occurs due to chronic inflammation, leading to the proliferation of fibroblasts and the excessive deposition of extracellular matrix (ECM). The process of lo...
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The influence of sleep factors and dietary habits on the disease pattern of ulcerative colitis patients with long and short disease courses – a multicentre cross-sectional analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Mingyue Guo, Gechong Ruan, Xueli Ding, Yanbo Yu, Linglin Tian, Jun Shen, Xiaoyin Bai, Lingjuan Jiang, Weiyang Zheng, Huijun Shu, Xiaolan Zhang, Hong Yang
Ulcerative colitis (UC) is a disease characterized by chronic relapsing-remitting inflammatory disorders and is associated with environmental changes.To explore the disease patterns of Chinese UC p...