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γδ T cells as unconventional targets of checkpoint blockade Nat. Cancer (IF 22.7) Pub Date : 2024-03-27 Hans R. Widlund, Lydia Lynch
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Tissue-specific thresholds of mutation burden associated with anti-PD-1/L1 therapy benefit and prognosis in microsatellite-stable cancers Nat. Cancer (IF 22.7) Pub Date : 2024-03-25 Maishara Muquith, Magdalena Espinoza, Andrew Elliott, Joanne Xiu, Andreas Seeber, Wafik El-Deiry, Emmanuel S. Antonarakis, Stephanie L. Graff, Michael J. Hall, Hossein Borghaei, Dave S. B. Hoon, Stephen V. Liu, Patrick C. Ma, Rana R. McKay, Trisha Wise-Draper, John Marshall, George W. Sledge, David Spetzler, Hao Zhu, David Hsiehchen
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Trans-Atlantic twists and turns Nat. Cancer (IF 22.7) Pub Date : 2024-03-22 Johanna A. Joyce
Johanna Joyce received her PhD from the University of Cambridge, and did postdoctoral research at the University of California, San Francisco. She then joined the faculty at Memorial Sloan Kettering Cancer Center, New York, becoming a tenured member in 2014. She moved to Switzerland in 2016, where she later served as the inaugural executive director of the Agora Cancer Center Lausanne. She is currently
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The pleiotropic functions of reactive oxygen species in cancer Nat. Cancer (IF 22.7) Pub Date : 2024-03-22 Katherine Wu, Ahmed Ezat El Zowalaty, Volkan I. Sayin, Thales Papagiannakopoulos
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Threonine fuels glioblastoma through YRDC-mediated codon-biased translational reprogramming Nat. Cancer (IF 22.7) Pub Date : 2024-03-22 Xujia Wu, Huairui Yuan, Qiulian Wu, Yixin Gao, Tingting Duan, Kailin Yang, Tengfei Huang, Shuai Wang, Fanen Yuan, Derrick Lee, Suchet Taori, Tritan Plute, Søren Heissel, Hanan Alwaseem, Michael Isay-Del Viscio, Henrik Molina, Sameer Agnihotri, Dennis J. Hsu, Nu Zhang, Jeremy N. Rich
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Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies Nat. Cancer (IF 22.7) Pub Date : 2024-03-19 Anton Dobrin, Pieter L. Lindenbergh, Yuzhe Shi, Karlo Perica, Hongyao Xie, Nayan Jain, Andrew Chow, Jedd D. Wolchok, Taha Merghoub, Michel Sadelain, Mohamad Hamieh
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Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells Nat. Cancer (IF 22.7) Pub Date : 2024-03-06 Tajinder Ubhi, Olga Zaslaver, Andrew T. Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M. O’Kane, Faiyaz Notta, Jason Moffat, Julie M. Wilson, Steven Gallinger, Beáta G. Vértessy, David A. Tuveson, Hannes L. Röst, Grant W. Brown
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A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors Nat. Cancer (IF 22.7) Pub Date : 2024-03-05 Sungjoon Park, Erica Silva, Akshat Singhal, Marcus R. Kelly, Kate Licon, Isabella Panagiotou, Catalina Fogg, Samson Fong, John J. Y. Lee, Xiaoyu Zhao, Robin Bachelder, Barbara A. Parker, Kay T. Yeung, Trey Ideker
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Improving long-term outcomes in pediatric low-grade glioma Nat. Cancer (IF 22.7) Pub Date : 2024-03-01 Johannes Gojo, Matthias Preusser
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Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy Nat. Cancer (IF 22.7) Pub Date : 2024-03-01 Ajay Subramanian, Neda Nemat-Gorgani, Timothy J. Ellis-Caleo, David G. P. van IJzendoorn, Timothy J. Sears, Anish Somani, Bogdan A. Luca, Maggie Y. Zhou, Martina Bradic, Ileana A. Torres, Eniola Oladipo, Christin New, Deborah E. Kenney, Raffi S. Avedian, Robert J. Steffner, Michael S. Binkley, David G. Mohler, William D. Tap, Sandra P. D’Angelo, Matt van de Rijn, Kristen N. Ganjoo, Nam Q. Bui, Gregory
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Modeling T cell temporal response to cancer immunotherapy rationalizes development of combinatorial treatment protocols Nat. Cancer (IF 22.7) Pub Date : 2024-03-01 Oren Barboy, Akhiad Bercovich, Hanjie Li, Yaniv Eyal-Lubling, Adam Yalin, Yuval Shapir Itai, Kathleen Abadie, Mor Zada, Eyal David, Shir Shlomi-Loubaton, Yonatan Katzenelenbogen, Diego Adhemar Jaitin, Chamutal Gur, Ido Yofe, Tali Feferman, Merav Cohen, Rony Dahan, Evan W. Newell, Aviezer Lifshitz, Amos Tanay, Ido Amit
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Temporal changes in treatment and late mortality and morbidity in adult survivors of childhood glioma: a report from the Childhood Cancer Survivor Study Nat. Cancer (IF 22.7) Pub Date : 2024-03-01 Peter M. K. de Blank, Katharine R. Lange, Mengqi Xing, Sedigheh Mirzaei Salehabadi, Deokumar Srivastava, Tara M. Brinkman, Kirsten K. Ness, Kevin C. Oeffinger, Joseph Neglia, Kevin R. Krull, Paul C. Nathan, Rebecca Howell, Lucie M. Turcotte, Wendy Leisenring, Gregory T. Armstrong, M. Fatih Okcu, Daniel C. Bowers
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ATX restricts anti-tumor eosinophil responses Nat. Cancer (IF 22.7) Pub Date : 2024-02-28 Sharon Grisaru-Tal, Ariel Munitz
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Redistribution of mutation risk in cancer Nat. Cancer (IF 22.7) Pub Date : 2024-02-28 Xiaoju Hu, Subhajyoti De
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Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity Nat. Cancer (IF 22.7) Pub Date : 2024-02-27 Haojie Dong, Xin He, Lei Zhang, Wei Chen, Yi-Chun Lin, Song-Bai Liu, Huafeng Wang, Le Xuan Truong Nguyen, Min Li, Yinghui Zhu, Dandan Zhao, Lucy Ghoda, Jonathan Serody, Benjamin Vincent, Leo Luznik, Ivana Gojo, Joshua Zeidner, Rui Su, Jianjun Chen, Ritin Sharma, Patrick Pirrotte, Xiwei Wu, Weidong Hu, Weidong Han, Binghui Shen, Ya-Huei Kuo, Jie Jin, Amandeep Salhotra, Jeffrey Wang, Guido Marcucci,
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Clearance of dead cells by efferocytosis promotes liver metastasis in pancreatic cancer Nat. Cancer (IF 22.7) Pub Date : 2024-02-20
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Clinical and translational attributes of immune-related adverse events Nat. Cancer (IF 22.7) Pub Date : 2024-02-15 Karijn P. M. Suijkerbuijk, Mick J. M. van Eijs, Femke van Wijk, Alexander M. M. Eggermont
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A randomized, non-comparative phase 2 study of neoadjuvant immune-checkpoint blockade in retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma Nat. Cancer (IF 22.7) Pub Date : 2024-02-13 Christina L. Roland, Elise F. Nassif Haddad, Emily Z. Keung, Wei-Lien Wang, Alexander J. Lazar, Heather Lin, Manoj Chelvanambi, Edwin R. Parra, Khalida Wani, B. Ashleigh Guadagnolo, Andrew J. Bishop, Elizabeth M. Burton, Kelly K. Hunt, Keila E. Torres, Barry W. Feig, Christopher P. Scally, Valerae O. Lewis, Justin E. Bird, Ravin Ratan, Dejka Araujo, M. Alexandra Zarzour, Shreyaskumar Patel, Robert
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Targeting LGR4–Wnt activates ferroptosis and reverses drug resistance in colorectal cancer Nat. Cancer (IF 22.7) Pub Date : 2024-02-14
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Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial Nat. Cancer (IF 22.7) Pub Date : 2024-02-14 Evanthia.T. Roussos Torres, Won J. Ho, Ludmila Danilova, Joseph A. Tandurella, James Leatherman, Christine Rafie, Chenguang Wang, Adam Brufsky, Patricia LoRusso, Vincent Chung, Yuan Yuan, Melinda Downs, Ashley O’Connor, Sarah M. Shin, Alexei Hernandez, Elizabeth L. Engle, Richard Piekarz, Howard Streicher, Zahra Talebi, Michelle A. Rudek, Qingfeng Zhu, Robert A. Anders, Ashley Cimino-Mathews, Elana
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Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis Nat. Cancer (IF 22.7) Pub Date : 2024-02-14 Yuliana Astuti, Meirion Raymant, Valeria Quaranta, Kim Clarke, Maidinaimu Abudula, Olivia Smith, Gaia Bellomo, Vatshala Chandran-Gorner, Craig Nourse, Christopher Halloran, Paula Ghaneh, Daniel Palmer, Robert P. Jones, Fiona Campbell, Jeffrey W. Pollard, Jennifer P. Morton, Ainhoa Mielgo, Michael C. Schmid
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The dopamine transporter antagonist vanoxerine inhibits G9a and suppresses cancer stem cell functions in colon tumors Nat. Cancer (IF 22.7) Pub Date : 2024-02-13 Christopher J. Bergin, Aïcha Zouggar, Amanda Mendes da Silva, Tanguy Fenouil, Joshua R. Haebe, Angelique N. Masibag, Gautam Agrawal, Muhammad S. Shah, Tamara Sandouka, Mario Tiberi, Rebecca C. Auer, Michele Ardolino, Yannick D. Benoit
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Repurposing the dopamine transporter antagonist vanoxerine to treat colorectal cancer Nat. Cancer (IF 22.7) Pub Date : 2024-02-13 Winnie Chen, Ian Maze
Self-renewing cancer stem cells drive tumor initiation and progression and represent a major target for therapeutic development. A study now shows that vanoxerine, a dopamine transporter antagonist, precisely inhibits this cell population in colorectal cancer, which leads to attenuation of tumor initiation and increased infiltration by immune cells.
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Melanoma leverages local cues to promote liver-specific metastasis Nat. Cancer (IF 22.7) Pub Date : 2024-02-12
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Integrated multiomic profiling of breast cancer in the Chinese population reveals patient stratification and therapeutic vulnerabilities Nat. Cancer (IF 22.7) Pub Date : 2024-02-12 Yi-Zhou Jiang, Ding Ma, Xi Jin, Yi Xiao, Ying Yu, Jinxiu Shi, Yi-Fan Zhou, Tong Fu, Cai-Jin Lin, Lei-Jie Dai, Cheng-Lin Liu, Shen Zhao, Guan-Hua Su, Wanwan Hou, Yaqing Liu, Qingwang Chen, Jingcheng Yang, Naixin Zhang, Wen-Juan Zhang, Wei Liu, Weigang Ge, Wen-Tao Yang, Chao You, Yajia Gu, Virginia Kaklamani, François Bertucci, Claire Verschraegen, Anneleen Daemen, Nakul M. Shah, Ting Wang, Tiannan Guo
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Mitochondrial DNA mutation enhances sensitivity to immunotherapy in melanoma Nat. Cancer (IF 22.7) Pub Date : 2024-02-09
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PD-L2 expression in senescent cancer cells limits tumor clearance after chemotherapy Nat. Cancer (IF 22.7) Pub Date : 2024-02-08
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Roadmap for a European cancer data management and precision medicine infrastructure Nat. Cancer (IF 22.7) Pub Date : 2024-02-06 Macha Nikolski, Eivind Hovig, Fatima Al-Shahrour, Niklas Blomberg, Serena Scollen, Alfonso Valencia, Gary Saunders
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Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency Nat. Cancer (IF 22.7) Pub Date : 2024-02-02 Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R. Kulkarni, Sevinç Jakab, Till Rostalski, Carleen Spegg, Simon Anders, Hellmut G. Augustin
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Telomerase inhibitor imetelstat kills AML cells via lipid ROS and ferroptosis Nat. Cancer (IF 22.7) Pub Date : 2024-01-30
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Lessons from withdrawn accelerated approvals in oncology Nat. Cancer (IF 22.7) Pub Date : 2024-01-30 George S. Mellgard, Tito Fojo, Susan E. Bates
Drug regulatory agencies in the USA and Europe have mechanisms to provide patients faster access to novel treatments, expecting that follow-up trials will confirm clinically meaningful results. However, some early approvals are subsequently withdrawn. Here we discuss the insights gained from withdrawn accelerated approvals for oncologic agents in the past decade.
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Glutamine analogs for pancreatic cancer therapy Nat. Cancer (IF 22.7) Pub Date : 2024-01-30 Nada Y. Kalaany
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Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance Nat. Cancer (IF 22.7) Pub Date : 2024-01-30 Hao Zheng, Jinming Liu, Qi Cheng, Qianping Zhang, Yaoyao Zhang, Lingyu Jiang, Yan Huang, Wenlei Li, Yanping Zhao, Guo Chen, Fan Yu, Lei Liu, Yanjun Li, Xudong Liao, Lai Xu, Yi Xiao, Zhibo Zheng, Ming Li, Hongyi Wang, Gang Hu, Lei Du, Quan Chen
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Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma Nat. Cancer (IF 22.7) Pub Date : 2024-01-29 Mahnoor Mahmood, Eric Minwei Liu, Amy L. Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L. Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L. Manchon, Crístina Rodríguez-Antona, Rowan C. Walters, Roger J. Springett, James N. Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W. Roberts, Ed Reznik, Payam A. Gammage
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Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation Nat. Cancer (IF 22.7) Pub Date : 2024-01-29 Meri Rogava, Tyler J. Aprati, Wei-Yu Chi, Johannes C. Melms, Clemens Hug, Stephanie H. Davis, Ethan M. Earlie, Charlie Chung, Sachin K. Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J. Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler
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Aneuploidy and complex genomic rearrangements in cancer evolution Nat. Cancer (IF 22.7) Pub Date : 2024-01-29 Toby M. Baker, Sara Waise, Maxime Tarabichi, Peter Van Loo
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Artificial intelligence uses multi-omic data to predict pancreatic cancer outcomes Nat. Cancer (IF 22.7) Pub Date : 2024-01-26
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Lipids as mediators of cancer progression and metastasis Nat. Cancer (IF 22.7) Pub Date : 2024-01-25 Felix C. E. Vogel, Adriano B. Chaves-Filho, Almut Schulze
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Therapeutic targeting of the KIF18A motor protein in cancers with chromosomal instability Nat. Cancer (IF 22.7) Pub Date : 2024-01-24
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The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2 Nat. Cancer (IF 22.7) Pub Date : 2024-01-24 Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fatima Al-Shahrour, Timothy P. Cash, Tamara Tchkonia, James L. Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
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Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy Nat. Cancer (IF 22.7) Pub Date : 2024-01-24 Yu-Kai Huang, Wei-Chung Cheng, Ting-Ting Kuo, Juan-Cheng Yang, Yang-Chang Wu, Heng-Hsiung Wu, Chia-Chien Lo, Chih-Ying Hsieh, Sze-Ching Wong, Chih-Hao Lu, Wan-Ling Wu, Shih-Jen Liu, Yi-Chuan Li, Ching-Chan Lin, Chia-Ning Shen, Mien-Chie Hung, Jaw-Town Lin, Chun-Chieh Yeh, Yuh-Pyng Sher
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Immunomodulatory microbial metabolites as potential predictors of stem-cell transplantation outcomes Nat. Cancer (IF 22.7) Pub Date : 2024-01-23
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The Molecular Twin artificial-intelligence platform integrates multi-omic data to predict outcomes for pancreatic adenocarcinoma patients Nat. Cancer (IF 22.7) Pub Date : 2024-01-22 Arsen Osipov, Ognjen Nikolic, Arkadiusz Gertych, Sarah Parker, Andrew Hendifar, Pranav Singh, Darya Filippova, Grant Dagliyan, Cristina R. Ferrone, Lei Zheng, Jason H. Moore, Warren Tourtellotte, Jennifer E. Van Eyk, Dan Theodorescu
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Towards accurate genomics for newly diagnosed metastatic prostate cancer Nat. Cancer (IF 22.7) Pub Date : 2024-01-17
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INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas Nat. Cancer (IF 22.7) Pub Date : 2024-01-17 Ahmed M. O. Elbatsh, Ali Amin-Mansour, Anne Haberkorn, Claudia Textor, Nicolas Ebel, Emilie Renard, Lisa M. Koch, Femke C. Groenveld, Michelle Piquet, Ulrike Naumann, David A. Ruddy, Vincent Romanet, Julia M. Martínez Gómez, Matthew D. Shirley, Peter Wipfli, Christian Schnell, Markus Wartmann, Martin Rausch, Martine J. Jager, Mitchell P. Levesque, Sauveur-Michel Maira, Eusebio Manchado
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Intra-tumoral T cells in pediatric brain tumors display clonal expansion and effector properties Nat. Cancer (IF 22.7) Pub Date : 2024-01-16 Aditi Upadhye, Kevin E. Meza Landeros, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, Edwin Woo, Serena J. Chee, Denise Malicki, Nicole G. Coufal, David Gonda, Michael L. Levy, Jason A. Greenbaum, Grégory Seumois, John Crawford, William D. Roberts, Stephen P. Schoenberger, Hilde Cheroutre, Christian H. Ottensmeier, Pandurangan Vijayanand, Anusha-Preethi Ganesan
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Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial Nat. Cancer (IF 22.7) Pub Date : 2024-01-12 Stephen J. Bagley, Zev A. Binder, Lamia Lamrani, Eliana Marinari, Arati S. Desai, MacLean P. Nasrallah, Eileen Maloney, Steven Brem, Robert A. Lustig, Goldie Kurtz, Michelle Alonso-Basanta, Pierre-Emmanuel Bonté, Christel Goudot, Wilfrid Richer, Eliane Piaggio, Shawn Kothari, Lea Guyonnet, Coralie L. Guerin, Joshua J. Waterfall, Suyash Mohan, Wei-Ting Hwang, Oliver Y. Tang, Meghan Logun, Meghna Bhattacharyya
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Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47 Nat. Cancer (IF 22.7) Pub Date : 2024-01-10 Chunliu Huang, Xuefei Wang, Yingzhao Wang, Yongyi Feng, Xiumei Wang, Shan Chen, Peidong Yan, Jing Liao, Qi Zhang, Chengzhou Mao, Yang Li, Lixiang Wang, Xinyu Wang, Wei Yi, Weibin Cai, Shoudeng Chen, Ni Hong, Weiling He, Jun Chen, Wenfei Jin
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Cell cycle gene alterations associate with a redistribution of mutation risk across chromosomal domains in human cancers Nat. Cancer (IF 22.7) Pub Date : 2024-01-10 Marina Salvadores, Fran Supek
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The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Nat. Cancer (IF 22.7) Pub Date : 2024-01-10 Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J. Aitken, Allan Hackshaw, Andrew G. Nicholson, Mariam Jamal-Hanjani, Charles Swanton, Yinyin Yuan, John Le Quesne, David A. Moore
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MALAT1 protects dormant tumor cells from immune elimination Nat. Cancer (IF 22.7) Pub Date : 2024-01-09 Zhibin Zhang, Judy Lieberman
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LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells Nat. Cancer (IF 22.7) Pub Date : 2024-01-09 Dhiraj Kumar, Sreeharsha Gurrapu, Yan Wang, Seong-Yeon Bae, Poonam R. Pandey, Hong Chen, Jayanta Mondal, Hyunho Han, Chang-Jiun Wu, Spyros Karaiskos, Fei Yang, Aysegul Sahin, Ignacio I. Wistuba, Jianjun Gao, Debasish Tripathy, Hua Gao, Benjamin Izar, Filippo G. Giancotti
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Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression Nat. Cancer (IF 22.7) Pub Date : 2024-01-09 Sohinee Bhattacharyya, Chet Oon, Luis Diaz, Holly Sandborg, Erin S. Stempinski, Michelle Saoi, Terry K. Morgan, Claudia S. López, Justin R. Cross, Mara H. Sherman
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Reaching your destination can require a diversion Nat. Cancer (IF 22.7) Pub Date : 2024-01-03 Anirban Maitra
Anirban Maitra obtained his medical degree from the All India Institute of Medical Sciences, New Delhi, in 1996; this was followed by residency and fellowships in pathology at the University of Texas Southwestern Medical Center, Dallas, and Johns Hopkins University School of Medicine, Baltimore. From 2002 to 2013, he served as faculty in the departments of pathology and oncology at Johns Hopkins, before
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An oncolytic circular RNA therapy Nat. Cancer (IF 22.7) Pub Date : 2024-01-04 Alex G. Hamilton, Michael J. Mitchell
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Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping Nat. Cancer (IF 22.7) Pub Date : 2024-01-04 Evan W. Warner, Kim Van der Eecken, Andrew J. Murtha, Edmond M. Kwan, Cameron Herberts, Joonatan Sipola, Sarah W. S. Ng, Xinyi E. Chen, Nicolette M. Fonseca, Elie Ritch, Elena Schönlau, Cecily Q. Bernales, Gráinne Donnellan, Aslı D. Munzur, Karan Parekh, Kevin Beja, Amanda Wong, Sofie Verbeke, Nicolaas Lumen, Jo Van Dorpe, Bram De Laere, Matti Annala, Gillian Vandekerkhove, Piet Ost, Alexander W. Wyatt
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Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease Nat. Cancer (IF 22.7) Pub Date : 2024-01-04 Josef Leibold, Kaloyan M. Tsanov, Corina Amor, Yu-Jui Ho, Francisco J. Sánchez-Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E. Wilkinson, Scott W. Lowe
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An autologous antigen-agnostic dendritic cell therapy that forgoes antigen loading Nat. Cancer (IF 22.7) Pub Date : 2024-01-03
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Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism Nat. Cancer (IF 22.7) Pub Date : 2024-01-03 Linjie Zhao, Zhixin Qiu, Zhengnan Yang, Lian Xu, Thomas M. Pearce, Qiulian Wu, Kailin Yang, FuLong Li, Olivier Saulnier, Fan Fei, Huaxu Yu, Ryan C. Gimple, Venkateshwari Varadharajan, Juxiu Liu, Liam D. Hendrikse, Vernon Fong, Wei Wang, Jiao Zhang, Deguan Lv, Derrick Lee, Brandon M. Lehrich, Chunyu Jin, Liang Ouyang, Deobrat Dixit, Haoxing Wu, Xiang Wang, Andrew E. Sloan, Xiuxing Wang, Tao Huan, J
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Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation Nat. Cancer (IF 22.7) Pub Date : 2024-01-03 Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius C. Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Jürgen