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Metformin’s role in lowering colorectal cancer risk among individuals with diabetes from the Southern Community Cohort Study Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-21 Thomas Lawler, Zoe L. Walts, Lauren Giurini, Mark Steinwandel, Loren Lipworth, Harvey J. Murff, Wei Zheng, Shaneda Warren Andersen
Metformin, utilized to manage hyperglycemia, has been linked to a reduced risk of colorectal cancer (CRC) among individuals with diabetes. However, evidence is lacking for non-Hispanic Black individuals and those with lower socioeconomic status (SES), who face elevated risk for both diabetes and CRC. In this study, we investigated the association between metformin use and incident CRC risk within the
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Stage of diagnosis and survival for prostate cancer among immigrant men in Ontario, Canada Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-21 Aisha K. Lofters, Stacie-Ann Sammott, Sarah Swayze, Jacqueline L. Bender, Shabbir M.H. Alibhai, Anthony Henry, Kenneth Noel, Geetanjali Datta
We previously identified specific immigrant groups (West African and Caribbean) with increased incidence of prostate cancer in Ontario, Canada. In this population-level retrospective cohort study, we used administrative databases to compare stage of diagnosis, 5-year overall survival and prostate cancer-specific survival for immigrants versus long-term residents of Ontario. We linked several provincial-level
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Feasibility and limitations of using commercial databases to evaluate residential mobility in registry-based research on childhood cancer Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-15 Lisa M. McKenzie, William B. Allshouse, Myles Cockburn, Debashis Ghosh
Researchers have used commercial databases containing residential addresses to reduce exposure misclassification in case-control studies. Our objective is to evaluate the potential systematic bias regarding case status when reconstructing residential locations from commercial databases. Our study population of 3640 Colorado-born children includes 520 children diagnosed with acute lymphocytic leukemia
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Cadmium in biological samples and site-specific cancer risk and mortality: A systematic review of original articles and meta-analyses Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-12 Alice Fanfani, Sophia Papini, Emma Bortolotti, Giulia Vagnoni, Calogero Saieva, Guglielmo Bonaccorsi, Saverio Caini
Cadmium (Cd) is classified as a class 1 carcinogen by the IARC, yet uncertainty persists regarding the total burden of cancer (incidence and mortality) caused by exposure to it, due to the still limited evidence with regard to its aetiological role in cancer at several body sites. We searched PubMed and EMBASE for meta-analyses and original articles published by February 1st, 2024, that focused on
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Hospitalization as an opportunity to improve lung cancer screening in high-risk patients Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-08 Ellen M. Nielsen, Jingwen Zhang, Justin Marsden, Chloe Bays, William P. Moran, Patrick D. Mauldin, Leslie A. Lenert, Benjamin A. Toll, Andrew D. Schreiner, Marc Heincelman
Lung cancer screening with annual low-dose computed tomography (LDCT) in high-risk patients with exposure to smoking reduces lung cancer-related mortality, yet the screening rate of eligible adults is low. As hospitalization is an opportune moment to engage patients in their overall health, it may be an opportunity to improve rates of lung cancer screening. Prior to implementing a hospital-based lung
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Maternal smoking and the risk of childhood brain tumors Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-07 Chongxian Hou, Zihao Hu, Yiquan Ke
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Oral prednisolone and warfarin and risk of oesophageal cancer: A case-control study. Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-06 Chris R. Cardwell, Ronald D. McDowell, Carmel M. Hughes, John Busby, Peter Murchie
A recent epidemiological study systematically screened 250 prescription medications for associations with oesophageal cancer risk, using Scottish data, and identified an increased risk with use of prednisolone and warfarin. We investigated whether oral prednisolone or warfarin use was associated with increased oesophageal cancer risk. A case-control study was conducted within the Clinical Practice
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Impact of the coronavirus disease 2019 pandemic on primary and metastatic lung cancer treatments in Japan: A nationwide study using an interrupted time series analysis Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-05 Misuzu Fujita, Takehiko Fujisawa, Kiminori Suzuki, Kengo Nagashima, Tokuzo Kasai, Hideyuki Hashimoto, Kazuya Yamaguchi, Yoshihiro Onouchi, Daisuke Sato, Akira Hata
The coronavirus disease 2019 pandemic prompted healthcare providers to use different approaches from the current standards of care. We aimed to identify the changes in the number of treatments for primary non-small cell lung cancer (NSCLC) and metastatic lung cancer during the pandemic. We used nationwide insurance claims data from January 2015 to January 2021, and estimated changes in the number of
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Prognostic factors in high-grade pediatric osteosarcoma among children and young adults: Greek Nationwide Registry for Childhood Hematological Malignancies and Solid Tumors (NARECHEM-ST) data along with a systematic review and meta-analysis Cancer Epidemiol. (IF 2.6) Pub Date : 2024-03-05 Evgenia Papakonstantinou, Kleoniki I. Athanasiadou, Georgios Markozannes, Vassiliki Tzotzola, Evdoxia Bouka, Margarita Baka, Maria Moschovi, Sophia Polychronopoulou, Emmanuel Hatzipantelis, Vasiliki Galani, Kalliopi Stefanaki, Katerina Strantzia, Maria Vousvouki, Panagiota Kourou, Evgenia Magkou, Maria Nikita, Christos Zambakides, John Michelarakis, Aikaterini Alexopoulou, Maro Gavra, Astero Malama
The 5-year overall survival of children and adolescents with osteosarcoma has been in plateau during the last 30 years. The present systematic review (1976–2023) and meta-analysis aimed to explore factors implicated in the prognosis of children and young adults with high-grade osteosarcoma. Original studies including patients ≤30 years and the Nationwide Registry for Childhood Hematological Malignancies
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Age-period-cohort effects on incidence trends of childhood leukemia from four population-based cancer registries in Colombia Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-29 Natalia Godoy-Casasbuenas, Carlos Javier Rincón, Fabian Gil, Nelson Arias, Claudia Uribe Pérez, María Clara Yépez, Esther de Vries
Childhood leukemia (CL) is the most prevalent form of pediatric cancer on a global scale. However, there is a limited understanding of the dynamics of CL incidence in South America, with a specific knowledge gap in Colombia. This study aimed to identify trends in CL incidence and to analyze the effects of age, period, and birth cohort on the risk of leukemia incidence in this population. Information
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Response to comments on: “Maternal smoking and the risk of childhood brain tumors” Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-21 Felix M. Onyije, Roya Dolatkhah, Ann Olsson, Liacine Bouaoun, Isabelle Deltour, Friederike Erdmann, Audrey Bonaventure, Michael E. Scheurer, Jacqueline Clavel, Joachim Schüz
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Survival differences in non-seminoma testis cancer patients according to race/ethnicity Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-20 Reha-Baris Incesu, Francesco Barletta, Stefano Tappero, Mattia Luca Piccinelli, Cristina Cano Garcia, Simone Morra, Lukas Scheipner, Zhe Tian, Fred Saad, Shahrokh F. Shariat, Sascha Ahyai, Nicola Longo, Felix K.H. Chun, Ottavio de Cobelli, Carlo Terrone, Alberto Briganti, Derya Tilki, Markus Graefen, Pierre I. Karakiewicz
Historic evidence suggests that non-Caucasian race/ethnicity predisposes to higher testis cancer-specific mortality (CSM) in non-seminoma. However, it is unknown, whether higher CSM in non-Caucasians applies to Hispanics or Asians or African-Americans, or all of the above groups. In contemporary patients, we tested whether CSM is higher in these select non-Caucasian groups than in Caucasians, in overall
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BMI and breast cancer risk around age at menopause Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-19 Ann Von Holle, Hans-Olov Adami, Laura Baglietto, Amy Berrington de Gonzalez, Kimberly A. Bertrand, William Blot, Yu Chen, Jessica Clague DeHart, Laure Dossus, A. Heather Eliassen, Agnes Fournier, Montse Garcia-Closas, Graham Giles, Marcela Guevara, Susan E. Hankinson, Alicia Heath, Michael E. Jones, Corinne E. Joshu, Rudolf Kaaks, Victoria A. Kirsh, Cari M. Kitahara, Woon-Puay Koh, Martha S. Linet
A high body mass index (BMI, kg/m) is associated with decreased risk of breast cancer before menopause, but increased risk after menopause. Exactly when this reversal occurs in relation to menopause is unclear. Locating that change point could provide insight into the role of adiposity in breast cancer etiology. We examined the association between BMI and breast cancer risk in the Premenopausal Breast
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Incidence trends of adult glioma in Norway and its association with occupation and education: A registry-based cohort study Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-17 Mohammad Jalil Sharifian, Jannicke Igland, Kari Klungsøyr, Anders Engeland, Ange Zhou, Tone Bjørge
Gliomas constitute 75 % of all malignant primary adult brain tumors. Being the most frequent histologic subtype, glioblastomas (GBMs) cause substantial morbidity and mortality worldwide and the Nordic countries have some of the highest incidence rates in the world. Therefore, we investigated the incidence of gliomas in Norway including time trends and associations with education and occupation. We
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Introduction of the Danish Lung Nodule Registry: A part of the Danish Lung Cancer Registry Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-16 Morten Borg, Torben Riis Rasmussen, Ole Hilberg
The majority of lung cancer cases are diagnosed late, resulting in poor prognosis and high mortality rates. Early detection and management of lung cancer can improve patient outcomes and reduce mortality rates. Pulmonary nodules are key factors in the early detection of lung cancer, they are common in high-risk populations and require correct classification to determine whether they are benign or malignant
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Corrigendum to “Lifetime occupational and recreational physical activity and risk of lymphoma subtypes. Results from the European Epilymph case-control study” [Cancer Epidemiol. 87 (2023) 102495] Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-14 Federico Meloni, Yolanda Benavente, Nikolaus Becker, Delphine Casabonne, Lenka Foretova, Marc Maynadié, Alexandra Nieters, Anthony Staines, Carlotta Trobbiani, Ilaria Pilia, Mariagrazia Zucca, Pierluigi Cocco
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Biased effects of pre-diagnostic physical activity on breast cancer survival: Systematic review and meta-analysis Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-14 Ziyu Wang, Frances EM Albers, Sabrina E. Wang, Dallas R. English, Brigid M. Lynch
Pre-diagnostic physical activity is reported to improve survival for women with breast cancer. However, studies of pre-diagnostic exposures and cancer survival are susceptible to bias, made clear when applying a target trial framework. We investigated the impact of selection bias, immortal time bias, confounding and bias due to inappropriate adjustment for post-exposure variables in a systematic review
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Incidence of papillary thyroid cancer: Comparison of the military and the general population by race and tumor stage/size Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-09 Julie A. Bytnar, Lindsey Enewold, Craig D. Shriver, Kangmin Zhu
A previous study found higher papillary thyroid cancer incidence in the US military than the general population with larger differences among Black than White individuals. This study compared the two populations in the incidence by sex, race, tumor stage, and size to assess possible factors related to identified differences. Subjects were aged 18–59 in the military and general populations. Papillary
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Alcohol consumption and 10-year mortality in oral and pharyngeal cancer Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-06 Shihoko Koyama, Takahiro Tabuchi, Toshitaka Morishima, Isao Miyashiro
Previous studies on the association of alcohol drinking with the prognosis of patients with oral and pharyngeal cancer are scarce and conflicting. Most previous studies are surveys from Europe, and examined up to 5 years of overall survival. We therefore evaluated the association between alcohol consumption and 10-year mortality among oral and pharyngeal cancer patients in Japan. 2626 eligible cancer
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The impact of individual-level income predicted from the BRFSS on the association between insurance status and overall survival among adults with cancer from the SEER program Cancer Epidemiol. (IF 2.6) Pub Date : 2024-02-06 Justin M. Barnes, Kimberly J. Johnson, Nosayaba Osazuwa-Peters, Matthew B. Spraker
Among patients with cancer in the United States, Medicaid insurance is associated with worse outcomes than private insurance and with similar outcomes as being uninsured. However, prior studies have not addressed the impact of individual-level socioeconomic status, which determines Medicaid eligibility, on the associations of Medicaid status and cancer outcomes. Our objective was to determine whether
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Multiple myeloma incidence, mortality, and survival differences at the intersection of sex, age, and race/ethnicity: A comparison between Puerto Rico and the United States SEER population Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-31 Maira A. Castañeda-Avila, Tonatiuh Suárez-Ramos, Carlos R. Torres-Cintrón, Mara M. Epstein, Axel Gierbolini-Bermúdez, Guillermo Tortolero-Luna, Karen J. Ortiz-Ortiz
Multiple myeloma (MM) survival has increased during the last decades due to the introduction of new therapies. We investigated the intersectionality among age, sex, and race/ethnicity to better understand the pattern of MM incidence, mortality, and survival. Puerto Rico (PR) Central Cancer Registry and the United States of America (US) Surveillance, Epidemiology, and End Results (SEER) Program databases
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Risk of secondary primary malignancies in survivors of upper tract urothelial carcinoma: A nationwide population-based analysis Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-28 Kuan-Yu Wu, Ian-Seng Cheong, Jung-Nien Lai, Che-Yuan Hu, Kuo-Chuan Hung, Yi-Ting Chen, Lu-Ting Chiu, Hsin-Tzu Tsai, Yeong-Chin Jou, Tzong-Shin Tzai, Yuh-Shyan Tsai
To investigate the cancer types and risk factors of secondary primary malignancy (SPM) in patients with upper tract urothelial carcinoma (UTUC) in Taiwan. Using National Health Insurance Research Dataset and catastrophic illness registry, we enrolled newly diagnosed UTUC patients from 2000 to 2013. Those without catastrophic illness registration were excluded from the study. The cancer types and hazard
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The growing cancer burden: Age-period-cohort projections in Aotearoa New Zealand 2020-2044 Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-26 Andrea Teng, James Stanley, Christopher Jackson, Jonathan Koea, Chunhuan Lao, Ross Lawrenson, Ineke Meredith, Dianne Sika-Paotonu, Jason Gurney
Cancer is a major cause of premature death and inequity, and global case numbers are rapidly expanding. This study projects future cancer numbers and incidence rates in Aotearoa New Zealand. Age-period-cohort modelling was applied to 25-years of national data to project cancer cases and incidence trends from 2020 to 2044. Nationally mandated cancer registry data and official historical and projected
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Incidence and centralization of chordoma in the Netherlands: A nationwide study between 1991 and 2020 Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-25 A. Lipplaa, R.J.P. van der Wal, A.D.G. Krol, W.C. Peul, J.V.M.G. Bovée, H. Gelderblom
Chordomas are rare malignant bone tumors arising in the axial skeleton, with an incidence of 0.3–0.88 per million inhabitants. We studied the annual incidence rate and centralization of treatment for chordoma in the Netherlands. We retrieved pathology excerpts from the PALGA nationwide Dutch Pathology Registry between 1991 and 2019 for patients with a chordoma to calculate incidence rates. From pathology
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Association of alcohol consumption, betel nut chewing, and cigarette smoking with mortality in patients with head and neck cancer among the Taiwanese population: A nationwide population-based cohort study Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-23 Ming-Jang Su, Chung-Han Ho, Chih-Ching Yeh
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Socio-demographic inequalities in stage at diagnosis of lung cancer: A French population-based study Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-17 Alexandre Quillet, Nolwenn Le Stang, Nicolas Meriau, Nicolas Isambert, Gautier Defossez
Diagnosing patients at a non-advanced stage has become a mainstay of lung cancer prevention and control strategies. Understanding socio-demographic inequalities in stage at diagnosis may improve the targeting of interventions on patients at higher risk. This study aimed to identify these socio-demographic determinants in a large-scale French population-based cancer registry. All incident lung cancers
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Breast cancer incidence trends in Golestan, Iran: An age-period-cohort analysis by ethnic region, 2004-2018 Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-15 Fatemeh Ghasemi-Kebria, Abdolreza Fazel, Shahryar Semnani, Arash Etemadi, Mohammad Naeimi-Tabiei, Susan Hasanpour-Heidari, Faezeh Salamat, Nastaran Jafari-Delouie, SeyedMehdi Sedaghat, Hamideh Sadeghzadeh, Mahnaz Akbari, Mahshid Mehrjerdian, Elisabete Weiderpass, Gholamreza Roshandel, Freddie Bray, Reza Malekzadeh
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Risk of cancer in relatives of patients with myelodysplastic neoplasia and acute leukemias Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-09 Nikolaj Juul Nitschke, Klaus Rostgaard, Mette Klarskov Andersen, Henrik Hjalgrim, Kirsten Grønbæk
Background The risk of cancer among relatives of patients with either myelodysplastic neoplasia (MDS), acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) has not been thoroughly examined. Methods We linked the Danish Civil Registration System with the Danish Cancer Registry, the Danish National Acute Leukemia Registry, and the Danish Myelodysplastic Syndrome Database to estimate the
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Cancer mortality in Germany-born Americans and Germans Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-05 Silvia Mignozzi, Claudia Santucci, Heidy N. Medina, Eva Negri, Carlo La Vecchia, Paulo S. Pinheiro
Introduction Comparing cancer mortality and associated risk factors among immigrant populations in a host country to those in their country of origin reveals disparities in cancer risk, access to care, diagnosis, and disease management. This study compares cancer mortality between the German resident population and Germany-born individuals who migrated to the US. Methods Cancer mortality data from
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Treatment of pancreatic adenocarcinoma in relation to survival in the U.S. Military Health System Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-06 Yvonne L. Eaglehouse, Sarah Darmon, Amie B. Park, Craig D. Shriver, Kangmin Zhu
Background Pancreatic cancer has a high case fatality and relatively short survival after diagnosis. Treatment is paramount to improving survival, but studies on the effects of standard treatment by surgery or chemotherapy on survival in U.S. healthcare settings is limited. Further, variability in access to care may impact treatment and outcomes for patients. We aimed to assess the relationship between
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The reduced mortality of malignant melanoma at the population level is mainly attributable to treatment advances for the past decade Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-04 Si Li, Tian Tang, Jianglong Han, Wenmin Liu, Ruyan Chen, Haiyu Deng, Tingting Jian, Zhenming Fu
Background Cutaneous malignant melanoma (CMM) causes most skin cancer deaths in the United States (US). The mortality has been decreasing in the US population. We hypothesize that this population-level reduction is mainly attributable to the treatment advances, rather than the successful primary and secondary prevention. Methods Using data from the Surveillance, Epidemiology, and End Results (SEER)
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Polyphenol intake and gastric cancer: A case-control study in the Brazilian Amazon region Cancer Epidemiol. (IF 2.6) Pub Date : 2024-01-02 Marcela de Araújo Fagundes, Renata Alves Carnauba, Gisele Aparecida Fernandes, Paulo Pimentel de Assumpção, Maria Paula Curado
Background Polyphenol intake has been associated with a decreased risk of some types of cancer, including gastric cancer (GC). However, few studies address this topic in the Latin American population. In the present study, we evaluated the association between polyphenol intake and the risk of GC in the Brazilian Amazon region. Methods A case-control study was conducted in Belém (Amazon region) from
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Use of conditional estimates of effect in cancer epidemiology: An application to lung cancer treatment Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-30 Jazeel AbdulMajeed, Malkan Khatib, Mohamad Dulli, Stephanie Sioufi, Azhar Al-Khulaifi, Jennifer Stone, Luis Furuya-Kanamori, Adedayo A. Onitilo, Suhail A.R. Doi
Background In oncology clinical trials, there is the assumption that randomization sufficiently balances confounding covariates and therefore average treatment effects are usually reported. This paper explores the wider benefits provided by conditioning on covariates for reasons other than mitigation of confounding. Methods We reanalyzed the data from primary randomized controlled trials listed in
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Lymphoid blood cancers, incidence and survival 2005-2023: A report from the UK’s Haematological Malignancy Research Network Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-30 Maxine Lamb, Daniel Painter, Debra Howell, Sharon Barrans, Catherine Cargo, Ruth de Tute, Reuben Tooze, Cathy Burton, Russell Patmore, Eve Roman, Alexandra Smith
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Trends in gastric cancer incidence and mortality in Asia and association analysis with human development index, 1990-2019 Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-22 Yunxia Zhang, Pengyan Li, Jinxi Han, Yibo Liu, Jikai Liu, Mengyuan Li, Kaijuan Wang
Objectives To describe the epidemiological time trends and gender, age and regional differences of gastric cancer in Asia during 1990–2019, and to analyze the association between the human development index (HDI) and the statistical indicators of the burden of disease. Methods Describing trends in age-standardized incidence rates (ASIR) and age-standardized mortality rate (ASMR) in Asia from 1990 to
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Utility of prescription-based comorbidity indices for predicting mortality among Australian men with prostate cancer Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-22 Tenaw Tiruye, David Roder, Liesel M. FitzGerald, Michael O’Callaghan, Kim Moretti, Kerri Beckmann
Background Drug prescription registries has become an alternative data source to hospital admission databases for measuring comorbidities. However, the predictive validity of prescription-based comorbidity measures varies based on the population under investigation and outcome of interest. We aimed to determine which prescription-based index of comorbidity has most utility in Australian men with prostate
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Effect of patient and diagnostic intervals on the risk of advanced stage in Indian patients with seven types of gastrointestinal cancers: A retrospective cohort study Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-22 Sundeep Jain, Shyam Sundar Sharma, Deepak Kumar Gupta
Objectives Advanced stage is linked to prolonged patient and diagnostic interval for gastrointestinal (GI) cancers. However, objective evidence of this fact is not so forthcoming. Our aim was to study the effect of these intervals on the risk of advanced stage for GI cancers. Methods We performed this retrospective cohort study to analyse the effect of patient and diagnostic intervals on final stage
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Rural cancer disparities from Oklahoma cancer and vital records registries 2016–2020 Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-19 Janis E. Campbell, Ayesha B. Sambo, Lauri A. Hunsucker, Stephanie F. Pharr, Mark P. Doescher
Objectives Compared to Oklahoma, 33 states have higher all-cause cancer incidence rates, but only three states have higher all-cause cancer mortality rates. Given this troubling gap between Oklahoma’s cancer incidence and mortality rankings, in-depth examination of cancer incidence, staging, and mortality rates among this state’s high-risk populations is warranted. This study provides in-depth information
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Evaluating the efficacy of artificial intelligence tools for the automation of systematic reviews in cancer research: A systematic review Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-09 Xiaomei Yao, Mithilesh V. Kumar, Esther Su, Athena Flores Miranda, Ashirbani Saha, Jonathan Sussman
To evaluate the performance accuracy and workload savings of artificial intelligence (AI)-based automation tools in comparison with human reviewers in medical literature screening for systematic reviews (SR) of primary studies in cancer research in order to gain insights on improving the efficiency of producing SRs. Medline, Embase, the Cochrane Library, and PROSPERO databases were searched from inception
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Risk factors for childhood brain tumours: A systematic review and meta-analysis of observational studies from 1976 to 2022 Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-05 Felix M. Onyije, Roya Dolatkhah, Ann Olsson, Liacine Bouaoun, Isabelle Deltour, Friederike Erdmann, Audrey Bonaventure, Michael E. Scheurer, Jacqueline Clavel, Joachim Schüz
Background Childhood brain tumours (CBTs) are the leading cause of cancer death in children under the age of 20 years globally. Though the aetiology of CBT remains poorly understood, it is thought to be multifactorial. We aimed to synthesize potential risk factors for CBT to inform primary prevention. Methods We conducted a systematic review and meta-analysis of epidemiological studies indexed in the
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Gynaecological cancer incidence and mortality trends in a Brazilian State with medium human development index: A 22-year analysis Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-05 Brenda Evelin Barreto da Silva, Lígia Mara Dolce de Lemos, Alex Rodrigues Moura, Yasmim Anayr Costa Ferrari, Marcela Sampaio Lima, Marceli de Oliveira Santos, Carlos Anselmo Lima
Objective This study aimed to analyse trends in incidence and mortality rates of gynaecological cancer (GC) in Sergipe, a medium Human Development Index (HDI) state in northeastern Brazil during 1996–2017. Methods Data were obtained from the Population-based Cancer Registry of Aracaju and Brazilian Mortality Information System database. We included vulvar (VUC), vaginal (VAC), cervical (CC), uterine
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Geographic and temporal trends in pediatric and young adult brain tumors in Kentucky, 1995–2019 Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-05 W.J. Christian, C.J. Walker, J. McDowell, B. Huang, T.C. Tucker, J. Villano, E.B. Durbin
Introduction Pediatric and young adult brain tumors (PYBT) account for a large share of cancer-related morbidity and mortality among children in the United States, but their etiology is not well understood. Previous research suggests the Appalachian region of Kentucky has high rates of PYBT. This study explored PYBT incidence over 25 years in Kentucky to identify geographic and temporal trends and
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Impact of the COVID-19 pandemic on cancer screenings in Portugal Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-06 Diogo Mendes, Daniel Figueiredo, Carlos Alves, Ana Penedones, Beatriz Costa, Francisco Batel-Marques
Objectives This study aimed to evaluate the impact of the COVID-19 pandemic on cancer screening in Portugal, and its consequences on cancer morbidity and mortality. Methods The pre-pandemic and pandemic periods were compared using publicly available data on performance and health outcomes indicators of the Portuguese NHS, namely the numbers and proportions of eligible individuals who underwent cancer
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“Shared decision-making” for prostate cancer screening: Is it a marker of quality preventative healthcare? Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-05 Borivoj Golijanin, Vikas Bhatt, Alexander Homer, Kamil Malshy, Anna Ochsner, Rebecca Wales, Sari Khaleel, Anthony Mega, Gyan Pareek, Elias Hyams
Background “Shared decision-making” (SDM) is a cornerstone of prostate cancer (PCa) screening guidelines due to tradeoffs between clinical benefits and concerns for over-diagnosis and over-treatment. SDM requires effort by primary-care-providers (PCP) in an often busy clinical setting to understand patient preferences with the backdrop of patient risk factors. We hypothesized that SDM for PCa screening
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The frequency of using wearable activity trackers is associated with minutes of moderate to vigorous physical activity among cancer survivors: Analysis of HINTS data Cancer Epidemiol. (IF 2.6) Pub Date : 2023-12-01 Steven A. De La Torre, Trevor Pickering, Donna Spruijt-Metz, Albert J. Farias
Background Despite the health benefits, cancer survivors tend to exercise less after diagnosis and treatment. Wearable activity trackers (WATs) can provide avenues for self-monitoring and may enhance exercise motivation and enjoyment. However, less is known about the relationship between how often survivors use wearables and their amount of moderate to vigorous physical activity (MVPA). Methods Data
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Addressing discrepancies in oral cancer reporting: GLOBOCAN estimates versus ground reality in Latin America and the Caribbean Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-30 Alan Roger Santos-Silva, Josefina Martínez-Ramírez, Marcio Ajudarte Lopes
Abstract not available
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Investigating inequalities in cancer staging and survival for adults with intellectual or developmental disabilities and cancer: A population-based study in Manitoba, Canada Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-29 Rebecca Hansford, Hélène Ouellette-Kuntz, Michaela A. Bourque, Kathleen Decker, Shelley Derksen, Julie Hallet, David E. Dawe, Virginie Cobigo, Shahin Shooshtari, Morgan Stirling, Christine Kelly, Marni Brownell, Donna Turner, Alyson L. Mahar
Background Cancer is a leading cause of death among adults living with intellectual or developmental disabilities (IDD). However, few epidemiological studies exist worldwide quantifying inequalities in cancer stage at diagnosis and survival for people with IDD relative to those without IDD. Methods A population-based, retrospective cohort study was conducted using provincial health and social administrative
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Temporal trends in disease burden and attributable risk factors for tracheal, bronchus, and lung cancer in Nepal, 1990–2019 Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-25 Binfang Huang, Jinchao Hua, Shanshan Liu, Xu Wang, Zhonghe Sun, Ruhai Bai, Wanyue Dong
Background Tracheal, bronchus, and lung (TBL) cancer is one of the most common cancers in Nepal. The aim of this study was to analyze the changing disease burden and risk factors for TBL cancer in Nepal from 1990 to 2019. Methods TBL cancer burden data were obtained from the Global Burden of Disease Study 2019. A decomposition analysis was used to explore the impact of changes in population size, population
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The association between marital status and treatment initiation in lung cancer: A systematic review and meta-analysis of observational studies Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-21 Charlotte Lucy Richardson, Mariam Saeed, Linda Sharp, Adam Todd
Lung cancer is associated with high mortality, and significant health burden. Marital status has been associated with lung cancer survival. This systematic review and meta-analysis set out to investigate the association between marital status and treatment receipt in lung cancer. The search was conducted across three databases: Medline (OVID), Embase and CINAHL, from inception to June 2022. Retrospective
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Lifetime occupational and recreational physical activity and risk of lymphoma subtypes. Results from the European Epilymph case-control study Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-22 Federico Meloni, Yolanda Benavente, Nikolaus Becker, Casabonne Delphine, Lenka Foretova, Marc Maynadié, Alexandra Nieters, Anthony Staines, Carlotta Trobbiani, Ilaria Pilia, Mariagrazia Zucca, Pierluigi Cocco
Physical activity is known to convey protection against several cancers. However, results on the risk of lymphoma overall and its subtypes have been inconsistent. The aim of this study was to investigate occupational and recreational physical activity in relation to risk of lymphoma subtypes adjusting for established occupational risk factors. We applied standardized tools to assess energy expenditure
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Sunlight, vitamin D, vitamin D receptor polymorphisms, and risk of multiple myeloma: A systematic review Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-15 Simon Cheah, Dallas R. English, Simon J. Harrison, Claire M. Vajdic, Graham G. Giles, Roger L. Milne
This systematic review examines the relationship with multiple myeloma (MM) risk for sunlight and vitamin D related exposures, including vitamin D supplementation, circulating 25-hydroxyvitamin D concentration, personal ultraviolet B radiation exposure, ambient solar irradiance and vitamin D receptor (VDR) gene polymorphisms We conducted a search for terms related to multiple myeloma, vitamin D, vitamin
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Racial and ethnic minorities in lower income brackets are associated with late-stage diagnosis of non-ocular melanoma Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-17 Priyashma Joshi, Ifeanyichukwu Ogobuiro, Alexandra Hernandez, Gabriel De La Cruz Ku, Daniel George Noe, Lynn Feun, Zhao-Jun Liu, Mecker G. Möller
Introduction Despite advances in oncologic care, racial and socio-economic outcome disparities persist in non-ocular melanoma patients. However, the unmet need is understanding the population at risk for late tumor stage at diagnosis. We sought to analyze the groups with an increased risk of unfavorable tumor stage at diagnosis. Methods Patients with non-ocular melanoma were reviewed using the 2000–2019
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Association between cytomegalovirus infection and cancer‑related mortality in the US adults Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-17 Xiaoping Huang, Chao Yi, Qianqian Ji, Yaxian Meng, Aijie Zhang, Chongguang Yang, Liqiong Zhou, Yiqiang Zhan
Purpose In a nationwide cohort of US adults, an exploration of the association between cytomegalovirus (CMV) infection and cancer‑related mortality was conducted. Materials and methods We acquired data from the National Health and Nutrition Examination Survey III (1988–1994), including 11,138 individuals who were aged 18–90 years at enrollment and underwent CMV serology assessments. CMV infection was
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Trends in gastric cancer mortality 2005–2020 in Peru and its geographical areas: A joinpoint regression analysis Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-16 J. Smith Torres-Roman, Dante Julca-Marín, Dayana Ticona-Tiña, Carlos Quispe-Vicuña, Janina Bazalar-Palacios, Gabriel De La Cruz-Ku, Jorge Ybaseta-Medina
Background Gastric cancer (GC) is the leading cause of cancer death in Peru. However, information regarding trends in mortality rates in Peru and its geographical areas in the last few decades is lacking. Our objective was to describe GC mortality rates in Peru between 2005 and 2020. Methods Age standardized mortality rates (ASMR) were calculated per 100,000 person-years using the world SEGI standard
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The interaction between systemic inflammatory markers and polygenic risk score in breast cancer risk: A cohort study in the UK Biobank Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-16 Zixuan Yang, Yanyu Zhang, Mengjie Song, Xiaoxi Huang, Yuxiang Lin, Haomin Yang
Background Systemic inflammatory markers have been widely used in cancer prognosis prediction recently. However, there is limited knowledge regarding their impact on breast cancer risk and their interaction with polygenic risk scores. Methods A cohort study of 202,403 female participants from the UK Biobank were analyzed to estimate the hazard ratio (HR) for the incidence and mortality of breast cancer
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Global trends in esophageal cancer mortality with predictions to 2025, and in incidence by histotype Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-11 Claudia Santucci, Silvia Mignozzi, Matteo Malvezzi, Giulia Collatuzzo, Fabio Levi, Carlo La Vecchia, Eva Negri
Background Esophageal cancer (EC) is a malignancy with a poor prognosis. We provided a global overview of EC mortality, analyzing figures over the last three decades and estimating mortality rates for the year 2025. We also reported incidence trends and the distribution of squamous cell carcinoma (SCC) and adenocarcinoma (AC) in selected countries. Methods We considered EC trends in the age-standardised
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Stage-specific risk of colon and rectal cancer in patients presenting with rectal bleeding or change in bowel habit in primary care: A population-based cohort study Cancer Epidemiol. (IF 2.6) Pub Date : 2023-11-09 N. Zakkak, G. Lyratzopoulos, M. Barclay
Introduction Rectal bleeding and change in bowel habit are red-flag symptoms for colon and rectal cancer but how they relate to advanced stage disease is not adequately understood. Methods We analysed primary care electronic health records data on patients aged 30–99 years. Using logistic regression, we first examined the risk of colon and rectal cancer within 12 months in patients presenting with
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Lung cancer from suspicion to treatment: An indicator of healthcare access in Turkey Cancer Epidemiol. (IF 2.6) Pub Date : 2023-10-27 Deniz Kızılırmak, Zeynep Yılmaz Kaya, Gizem Gökçimen, Yavuz Havlucu, Beyhan Cengiz Özyurt, Baran Gündoğuş, Dorina Esendağlı, Bilkay Serez Kaya, İlker Yılmam, Yusuf Aydemir, Mücahit Çolak, Emine Afşin, Nazlı Çetin, Aytekin İdikut, Ceren Değirmenci, Özge Oral Tapan, Canan Gündüz Gürkan, Celalettin İbrahim Kocatürk, Gökçen Ömeroğlu Şimşek, Cem Emrah Kalafat, Pınar Çelik
Background Lung cancer is the leading cause of cancer-related deaths worldwide. Before beginning lung cancer treatment, it is necessary to complete procedures such as suspecting lung cancer, obtaining a pathologic diagnosis, and staging. This study aimed to investigate the processes from suspicion of lung cancer to diagnosis, staging, and treatment initiation. Methods The study was designed as a multicenter
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Impact of the COVID-19 pandemic on breast cancer incidence and tumor stage in the Netherlands and Norway: A population-based study Cancer Epidemiol. (IF 2.6) Pub Date : 2023-10-27 Anouk H. Eijkelboom, Linda de Munck, Marthe Larsen, Maarten J. Bijlsma, Vivianne C.G. Tjan-Heijnen, Carla H. van Gils, Mireille J.M. Broeders, Jan F. Nygård, Marc B.I. Lobbes, Charles W. Helsper, Ruud M. Pijnappel, Luc J.A. Strobbe, Jelle Wesseling, Solveig Hofvind, Sabine Siesling
Background Comparing the impact of the COVID-19 pandemic on the incidence of newly diagnosed breast tumors and their tumor stage between the Netherlands and Norway will help us understand the effect of differences in governmental and social reactions towards the pandemic. Methods Women newly diagnosed with breast cancer in 2017–2021 were selected from the Netherlands Cancer Registry and the Cancer