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Being an Oncologist—How I Evolved Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-03-23 Swarupa Mitra MD
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The Srimad Bhagavata Purana Book X: A Lesson in the Beauty of the Midnight Sky Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-03-23 Varun Kumar Chowdhry MD MBA
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Radiation Oncology Ransomware Attack Response Risk Analysis Using Failure Modes and Effects Analysis Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-03-19 Yevgeniy Vinogradskiy PhD, Leah Schubert PhD, Amy Taylor BS RTT, Shari Rudoler MD, James Lamb PhD
There have been numerous significant ransomware attacks impacting Radiation Oncology in the past 5 years. Research into ransomware attack response in Radiation Oncology has consisted of case reports and descriptive articles and has lacked quantitative studies. The purpose of this work was to identify the significant safety risks to patients being treated with radiation therapy during a ransomware attack
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Practical Considerations for the Treatment of an Adrenal Metastasis With Stereotactic Body Radiation Therapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-03-16 James B. Yu MD MHS, David J. Grew MD, Erin Sculley MMP, Kathryn Hitchcock MD, Minsun Kim PhD, Simon S. Lo MD
The purpose of this paper is to summarize 3 methods for treating adrenal metastases with stereotactic body radiation therapy. This article is not meant to provide consensus guidelines but rather to present 4 practical examples of treatment techniques using different treatment platforms from 3 institutions.
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Highlights of the 65th Annual Meeting of the American Association of Physicists in Medicine Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-03-15 Sara L. Thrower PhD, Brigid A. McDonald PhD, Minsun Kim PhD
The 65th annual meeting of the American Association of Physicists in Medicine took place in July 2023 with a theme of “The Art of Science, The Science of Care.” We review a sample of the more than 1000 talks and 1600 posters, focusing on a few topics of interest. Recent legislative changes across the country regarding reproductive health care have led to questions about how these regulations may affect
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To pass away on leap day Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-03-14 Gohar S. Manzar MD PhD
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Thoracic Reirradiation with Stereotactic Body Radiation Therapy (SBRT) for Recurrent Advanced Non-Small Cell Lung Cancer (NSCLC) Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-21 Dylan Ross BS, Dennis Chan MD, Ellen Kuo MD, Matthew Harkenrider MD
Non-small cell lung cancer (NSCLC) local control remains suboptimal with rates around 75%. Stereotactic body radiation therapy (SBRT) is an option for isolated local recurrences of small-volume recurrences. This study investigates the safety and efficacy of 60 Gy in 8 fractions in large-volume local recurrences. We conducted a retrospective chart review of patients treated with salvage SBRT for NSCLC
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Handling Patient Emergencies During Radiopharmaceutical Therapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-12 Nichole M. Maughan PhD, Jacqueline E. Zoberi PhD, Jose L. Garcia-Ramirez MS, Jeff M. Michalski MD MBA, Brian C. Baumann MD, Maxwell Amurao PhD, David Luechtefeld BS, Areti Marko RTT, Angela Nestel MSN RN, Hyun Kim MD
Radiopharmaceutical therapy (RPT) is a rapidly growing treatment modality. Though uncommon, patients may experience complications during their RPT treatment, which may trigger a rapid response from the hospital team. However, members of this team are typically not familiar with precautions for radiation safety. During these events, it is important to prioritize the patient's health over all else. There
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Navigating the Complexities of Lymph Node Management in Vulvar Cancer: Insights and Perspectives Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-07 Colin M. Harari MD, Jeffery V. Brower MD PhD, Dave K. Gaffney MD PhD, Kristin A. Bradley MD
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Implementation of a stereoscopic camera system for clinical electron simulation and treatment planning Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-06 Sameer Taneja, David L. Barbee, Richard F. Cohen, Martha Malin
Purpose A 3D stereoscopic camera system developed by .decimal was commissioned and implemented into the clinic to improve the efficiency of clinical electron simulations. Capabilities of the camera allowed simulations to be moved from the treatment vault into any room with a flat surface that could accommodate patient positioning devices, eliminating the need for clinical patient setup timeslots on
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Evaluating an academic radiation oncology position Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-06 Nicholas G Zaorsky, Daniel M Trifiletti, Neha Vapiwala
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Custom-Trained Deep Learning-Based Auto-Segmentation for Male Pelvic Iterative CBCT on C-Arm Linear Accelerators Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-06 Riley C. Tegtmeier, Christopher J. Kutyreff, Jennifer L. Smetanick, Dean Hobbis, Brady S. Laughlin, Diego A. Santos Toesca, Edward L. Clouser, Yi Rong
To evaluate the clinical applicability of a commercial artificial intelligence (AI)-driven deep learning auto-segmentation (DLAS) tool on enhanced iterative cone-beam CT (iCBCT) acquisitions for intact prostate and prostate bed treatments. DLAS models were trained using 116 iCBCT datasets with manually delineated organs-at-risk (OARs – bladder, femoral heads, and rectum) and target volumes (intact
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Intraoperative Radiation Therapy for Relapsed or Refractory High-Risk Neuroblastoma: A 27-Year Experience Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-02-02 Brianna Conte, Dana L. Casey, Kathryn R. Tringale, Joshua Honeyman, Nicole J.C. Narayan, Michael P. LaQuaglia, Justin Ted Gerstle, Shakeel Modak, Brian H. Kushner, Kim Kramer, Suzanne L. Wolden
To evaluate outcomes after intraoperative radiation therapy (IORT) in high-risk neuroblastoma (NB), including local control, overall survival, and toxicity. This was a single institution retrospective study of 92 pediatric patients with NB treated with IORT from 1995 to 2022. Each IORT application was considered a separate event for a total of 110 sites treated. Local failure was calculated using the
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Defining Minimum Treatment Parameters of Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma: An Expert Consensus Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-19 Ted K. Yanagihara, Joel E. Tepper, Andrew M. Moon, Aisling Barry, Meritxell Molla, Jinsil Seong, Ferran Torres, Smith Apisarnthanarax, Michael Buckstein, Higinia Cardenes, Daniel T. Chang, Mary Feng, Chandan Guha, Christopher L. Hallemeier, Maria A. Hawkins, Morten Hoyer, Hiromitsu Iwata, Salma K. Jabbour, Lisa Kachnic, Jordan Kharofa, Laura A. Dawson
Purpose External beam radiation therapy (EBRT) is a highly effective treatment in select patients with hepatocellular carcinoma (HCC). However, the Barcelona Clinic Liver Cancer system does not recommend the use of EBRT in HCC due to a lack of sufficient evidence and intends to perform an individual patient level meta-analysis of ablative EBRT in this population. However, there are many types of EBRT
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Academic and Geographic Employment Outcomes for Graduating Residents in Radiation Oncology: 2015-2022 Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-17 Kunal K. Sindhu, Kristin Hsieh, Tayler M. Sindhu, Jared P. Rowley
Purpose Little is known about how the academic and geographic employment outcomes of new radiation oncology (RO) graduates have changed over time. In this study, we sought to trace the evolution of these outcomes for all RO residents who graduated between 2015 and 2022. Methods and Materials Using publicly available data sources, we identified the first permanent, clinical employment positions accepted
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Systematic Implementation of Effective Quality Assurance Processes for the Assessment of Radiation Target Volumes in Head and Neck Cancer Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-17 E. Gogineni, D. Schaefer, A. Ewing, T. Andraos, D. DiCostanzo, M. Weldon, D. Christ, S. Baliga, S. Jhawar, D. Mitchell, J Grecula, D.J. Konieczkowski, J. Palmer, T. Jahraus, K. Dibs, A. Chakravarti, D. Martin, M.E. Gamez, D. Blakaj
Purpose Significant heterogeneity exists in clinical quality assurance (QA) practices within radiation oncology departments, with most chart rounds lacking prospective peer-reviewed contour evaluation. This has the potential to significantly affect patient outcomes, particularly for head and neck cancers (HNC) given the large variance in target volume delineation. With this understanding, we incorporated
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Practical implications of the ASTRO Radiation Oncology Case Rate Program (ROCR) proposal for radiation oncologists Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-16 James B. Yu, Join Y. Luh, Constantine A. Mantz
The American Society for Radiation Oncology (ASTRO) has proposed the Radiation Oncology Case Rate Program (ROCR) to advocate for fair reimbursement for radiation oncologists. ROCR would replace Medicare fee-for-service with a case rate payment for each of the 15 most common cancer types treated with external beam or stereotactic radiation therapy. This topic discussion attempts to provide a concise
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The Radiosurgery Society Case-Based Discussion of the Management of Head and Neck or Skull Base Paragangliomas with Stereotactic Radiosurgery and Radiotherapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-16 Felix Ehret, Daniel K. Ebner, Kyra N. McComas, Emile Gogineni, Therese Andraos, Minsun Kim, Simon Lo, Michael Schulder, Kristin J. Redmond, Alexander Muacevic, Helen A. Shih, John Kresl
Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) have been utilized for the treatment of head and neck or skull base paraganglioma for a considerable time, demonstrating promising local control rates and a favorable safety profile compared to surgical approaches. Nevertheless, the choice of treatment must be carefully tailored to each patient's preferences, tumor location
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Radiation-Induced Sensorineural Hearing Loss and Potential Management Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-10 Emily M Ishak, Matthew Gallitto, Justin S Golub, Michael B Sisti, Tony J.C. Wang
The cochlear apparatus is one of the major organs at risk (OARs) when considering radiotherapy (RT) for brain, head, and neck tumors. Radiation oncologists currently consider mean dose constraints of <35 gray (Gy) for conventionally fractioned RT, <4 Gy for single fraction stereotactic radiosurgery (SRS), and <17.1 or 25 Gy for 3- or 5-fraction SRS, respectively, as the standard of care. Indeed, dose
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Erratum to: Worrell SG, Goodman KA, Altorki NK, et al. The Society of Thoracic Surgeons/American Society for Radiation Oncology Updated Clinical Practice Guidelines on Multimodality Therapy for Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction. Pract Radiat Oncol. 2024;14:28-46 Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-05
Abstract not available
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Implementation and Efficacy of a Large-Scale Radiation Oncology Case-Based Peer-Review Quality Program across a Multinational Cancer Network Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-03 Ethan B. Ludmir, Karen E. Hoffman, Anuja Jhingran, Ramez Kouzy, Mee-chung Puscilla Ip, Laurie Sturdevant, Matthew S. Ning, Bruce D. Minsky, Mary Frances McAleer, Gregory M. Chronowski, Isidora Y. Arzu, Valerie Klairisa Reed, Amit K. Garg, Terence Roberts, Gary A. Eastwick, Michael R. Olson, Ugur Selek, Molly Gabel, Albert C. Koong, Michael E. Kupferman, Deborah A. Kuban
Purpose With expansion of academic cancer center networks across geographically-dispersed sites, ensuring high-quality delivery of care across all network affiliates is essential. We report on the characteristics and efficacy of a radiation oncology peer-review quality assurance (QA) system implemented across a large-scale multinational cancer network. Methods and Materials Since 2014, weekly case-based
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Neoadjuvant Chemotherapy and Surgery for Cervical Cancer, Timing of Surgery for Esophageal Cancer, Endometrial Cancer Molecular Classification, Vestibular Schwannoma, and Breast Boost Techniques Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-03 Laura Dover, Caleb Dulaney
Abstract not available
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Beyond Acceptable: The Vital Role of Medical Physicists in Ensuring High-Quality Treatment Plans Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-03 Mu-Han Lin, Lindsey Olsen, James A. Kavanaugh, Dustin Jacqmin, Eric Lobb, Sua Yoo, Sean L. Berry, Jose C. Pichardo, Carlos E. Cardenas, Justin Roper, Maura Kirk, Joey P. Cheung, Timothy D. Solberg, Kevin L. Moore, Minsun Kim
Abstract not available
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Radiation Therapy Summary of the AUA/ASTRO Guideline on Clinically Localized Prostate Cancer Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2024-01-03 Curtiland Deville, Sophia C. Kamran, Scott C. Morgan, Kosj Yamoah, Neha Vapiwala
Purpose Our purpose was to develop a summary of recommendations regarding the management of patients with clinically localized prostate cancer based on the American Urologic Association/ ASTRO Guideline on Clinically Localized Prostate Cancer. Methods The American Urologic Association and ASTRO convened a multidisciplinary, expert panel to develop recommendations based on a systematic literature review
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Pectoralis major radiation myonecrosis after lung stereotactic body radiation therapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-30 Jason Gurewitz, Anand Mahadevan, Benjamin T. Cooper
Abstract not available
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Adding a Small Field of View for Increased Resolution in Contouring: An Effective and Quick Method Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-30 Shreel Parikh, Ning Yue, Bruce Carmona, Jason Lambiase, Sung Kim
Image resolution is paramount when contouring complex anatomy, as in head & neck planning. It is notable that when diagnostic radiologists perform a CT scan of the neck, they always use a small field of view (SFOV) because it gives the best image resolution. When planning for radiation treatment, however, it is also necessary to have a large field of view (LFOV) in order to provide a comprehensive
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The Effect of Wire vs Magnetic Seed Localization on Lumpectomy Cavity Size Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-30 Michael Dykstra, Jessica Thompson, Jessica Aldous, Shannon Jiang, Tasha Hughes, James Hayman, Aleksandar Dragovic, Jennifer Shah, Alfred Chang, Corey Speers, Michael Sabel, Lesly Dossett, Matthew Schipper, Reshma Jagsi
Purpose To assess whether an association exists between surgical localization technique and lumpectomy cavity size on radiotherapy planning CT scan. Methods and Materials A single-institution retrospective review was conducted of women undergoing breast conserving surgery with wire- or magnetic seed- guided lumpectomy followed by adjuvant radiotherapy from 2018 to 2021. Patients of a surgeon only performing
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Adjuvant Radiotherapy for Salivary Duct and Epithelial Myoepithelial Salivary Carcinoma Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-30 Laura Freedman, Beth Beadle, Bhishamajit Chera, Jaylou Velez Torres
Abstract not available
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Locoregional Ablative Radiotherapy for Breast Cancer Patients Unsuitable for Surgical Resection Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-26 Daniel Moore-Palhares, Hanbo Chen, Benazir Mir Khan, Claire McCann, Sandi Bosnic, Ezra Hahn, Hany Soliman, Gregory Czarnota, Irene Karam, Eileen Rakovitch, Justin Lee, Danny Vesprini
Purpose Breast cancer patients unsuitable for surgical resection are typically managed with palliative systemic therapy alone. We report outcomes of 5-fraction ablative radiotherapy for non-resected breast cancers. Methods and Materials Retrospective analysis of an institutional registry of breast cancer patients unsuitable for resection who underwent 35-40 Gy/5 fractions to the primary breast tumour
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An automated, dynamic radiation oncology prescription checking system: Radiation prescription checking system Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-26 I.M. Pashtan, T. Kosak, K-Y Shin, C. Molodowitch, J.H. Killoran, C. Hancox, M. Czerminska, J.S. Bredfeldt, D.W. Cail, M. Kearney, R.B. Tishler, R.H. Mak
Background: Despite serving as a critical communication tool, radiation oncology prescriptions are entered manually and prone to error. An automated prescription checking system was developed and implemented to help address this problem. Methods: Rules defining clinically appropriate prescriptions were generated, examining specific types of errors: 1) Unapproved dose per fraction for a given disease
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On Teaching Narrative Oncology Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-17 Brian Quaranta
Abstract not available
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A Dose Accumulation Assessment of Alignment Errors During Spatially Fractionated Radiation Therapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-10 John Ginn, Sai Duriseti, Thomas Mazur, Matthew Spraker, James Kavanaugh
Introduction Spatially fractionated radiotherapy (SFRT) techniques produce high-dose peaks and low-dose valleys within a tumor. Lattice stereotactic body radiation therapy (SBRT) is a form a SFRT delivered across five fractions. Due to the high spatial dose gradients associated with SFRT, it is critical for fractionated SFRT patients to be aligned correctly for treatment. Here we investigate the dosimetric
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A Couch Mounted Smartphone-based Motion Monitoring System for Radiation Therapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-03 Dante P.I. Capaldi, Marian Axente, Amy S. Yu, Nicolas D. Prionas, Emily Hirata, Tomi F. Nano
Purpose Surface-guided radiation-therapy (SGRT) systems are being adopted into clinical practice for patient setup and motion monitoring. However, commercial systems remain cost prohibitive to resource-limited clinics around the world. Our aim is to develop and validate a smartphone-based application using LiDAR cameras (such as on recent Apple iOS devices) for facilitating SGRT in low-resource centers
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Path to Precision: Refining Radiotherapy Guidelines for Early-Stage Endometrial Cancer through Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-02 Jeffrey V. Brower, Amy J. Bregar, Ann H. Klopp
Abstract not available
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Automating the Treatment Planning Process for Volumetric Modulated Arc Therapy Craniospinal Irradiation (VMAT-CSI) Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-03 Ignacio O. Romero, Eric A. Simiele, Yuliia Lozko, Yuliia Severyn, Lawrie B. Skinner, Yong Yang, Jen-Yeu Wang, Lei Xing, Iris Gibbs, Susan M. Hiniker, Nataliya Kovalchuk
Purpose The purpose of this work is to develop a method to automate the treatment planning process of craniospinal irradiation (CSI) using volumetric modulated arc therapy (VMAT). Methods and Materials Two scripts were developed using the Eclipse Scripting Application Programming Interface (ESAPI) to perform auto-plan preparation and optimization. Ten patients (age, 5-44 years) previously treated at
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Evaluating the Quality-of-Life Impact of Apical Spacing with Hyaluronic Acid prior to Hypofractionated Prostate Radiation Therapy: A secondary analysis Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-02 Martin T. King, Michelle Svatos, Erik W. Chell, Vadim Pigrish, Katie Miller, Daniel A. Low, Peter F. Orio
Purpose Recently, a randomized trial demonstrated that a hyaluronic acid (HA) spacer placed prior to prostate hypofractionated intensity-modulated radiation therapy improved rectal dosimetry and reduced acute grade 2+ gastrointestinal toxicity. However, 26.5% of patients receiving the spacer experienced a minimal clinically important decline (MCID) in bowel quality-of-life (QOL). The purpose of this
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A Multi-Institutional Safety and Feasibility Study Exploring the Use of Hydrogel to Create Spatial Separation between the Pancreas and Duodenum in Patients with Pancreatic Cancer Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-12-02 Amol Kumar Narang MD, Theodore S. Hong MD, Kai Ding MS PhD, Joseph Herman MD, Jeffrey Meyer MS MD, Elizabeth Thompson MD, Manoop S. Bhutani MD, Kumar Krishnan MD, Brenna Casey MD, Eun Ji Shin MD PhD, Eugene J. Koay MD PhD
The administration of dose-escalated radiation for pancreatic adenocarcinoma remains challenging because of the proximity of dose-limiting stomach and bowel, particularly the duodenum for pancreatic head tumors. We explore whether endoscopic injection of a temporary, absorbable hydrogel into the pancreatico-duodenal (PD) groove is safe and feasible for the purpose of increasing spatial separation between
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Dose-volume predictors of radiation pneumonitis following thoracic hypofractionated radiotherapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-19 Alexander Sasse, Patrick Oh, Nadia Saeed, Daniel X. Yang, Thomas J. Hayman, Christin A. Knowlton, Gabrielle W. Peters, Allison Campbell, James Laird, Nadine Housri, Henry S. Park
Purpose/Objective(s) Hypofractionated radiation therapy (HFRT) is a common treatment for thoracic tumors, typically delivered as 60 Gy in 15 fractions. We aimed to identify dosimetric risk factors associated with radiation pneumonitis in patients receiving HFRT at 4 Gy per fraction, focusing on lung V20, mean lung dose (MLD), and lung V5 as potential predictors of grade ≥2 pneumonitis. Materials/Methods
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Stereotactic Body Radiation Therapy for the curative treatment of prostate cancer in ultra-large (≥100 cc) glands Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-19 Joshua C. Hurwitz, Jonathan Haas, Christopher Mendez, Astrid Sanchez, Vianca F. Santos, Meredith Akerman, Todd Carpenter, Moses Tam, Aaron Katz, Anthony Corcoran, Anand Mahadevan, Samir S. Taneja, Herbert Lepor, Jonathan W. Lischalk
Purpose Historically, toxicity concerns have existed in patients with large prostate glands treated with radiotherapy (RT), particularly brachytherapy. There are questions whether this risk extends to stereotactic body radiation therapy (SBRT). In this retrospective review, we examine clinical outcomes of patients with prostate glands ≥100 cc treated curatively with SBRT. Methods and Materials We retrospectively
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Publisher's Note to Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline (Pract Radiat Oncol. 2024;14:xxx-xxx. Epub ahead of print November 14, 2023.) Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-19 Simona F. Shaitelman, Bethany M. Anderson, Douglas W. Arthur, Jose G. Bazan, Jennifer R. Bellon, Lisa Bradfield, Charlotte E. Coles, Naamit K. Gerber, Madeera Kathpal, Leonard Kim, Christine Laronga, Icro Meattini, Elizabeth M. Nichols, Lori J. Pierce, Matthew M. Poppe, Patricia A. Spears, Shaveta Vinayak, Timothy Whelan, Janice A. Lyons
Abstract not available
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Real-world Utilization of Radiation Therapy in Multiple Myeloma: An Analysis of the Connect® MM Registry Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-19 Leslie Ballas, Sikander Ailawadhi, Mohit Narang, Cristina J. Gasparetto, Hans C. Lee, James W. Hardin, Brian G.M. Durie, Kathleen Toomey, James Omel, Lynne I. Wagner, Rafat Abonour, Howard R. Terebelo, Prashant Joshi, Edward Yu, Liang Liu, Robert M. Rifkin, Sundar Jagannath
Purpose Radiation therapy (RT) is an important treatment modality for patients with multiple myeloma (MM). While patients are living longer with MM, they are more likely to suffer from comorbidities related to treatment such as bone pain; however, RT can provide symptom relief. To date, the characterization of patients who have received RT in the real-world setting has been limited. Methods The Connect®
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Tungsten filled 3D printed lung blocks for total body irradiation Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-18 Dante P.I. Capaldi, Clinton Gibson, Annette Villa, Joseph B. Schulz, Benjamin P. Ziemer, Jie Fu, Piotr Dubrowski, Amy S. Yu, Shannon Fogh, Jessica Chew, Lauren Boreta, Steve E. Braunstein, Alon Witztum, Emily Hirata, Olivier Morin, Lawrie B. Skinner, Tomi F. Nano
Purpose Lung blocks for total-body-irradiation (TBI) are commonly used to reduce lung dose and prevent radiation pneumonitis. Currently, molten Cerrobend containing toxic materials, specifically lead and cadmium, is poured into molds to construct blocks. Here, we propose a streamlined method to create 3D-printed lung block shells and fill them with tungsten ball-bearings (BBs) to remove lead and improve
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Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-15 Simona F. Shaitelman, Bethany M. Anderson, Douglas W. Arthur, Jose G. Bazan, Jennifer R. Bellon, Lisa Bradfield, Charlotte E. Coles, Naamit K. Gerber, Madeera Kathpal, Leonard Kim, Christine Laronga, Icro Meattini, Elizabeth M. Nichols, Lori J. Pierce, Matthew M. Poppe, Patricia A. Spears, Shaveta Vinayak, Timothy Whelan, Janice A. Lyons
Purpose : This guideline provides evidence-based recommendations on appropriate indications and techniques for partial breast irradiation (PBI) for patients with early-stage invasive breast cancer and ductal carcinoma in situ. Methods : The American Society for Radiation Oncology (ASTRO) convened a task force to address 4 key questions focused on the appropriate indications and techniques for PBI as
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Dosimetric comparison of commonly used volumetric modulated arc therapy field arrangements based on flattening filter-free beams for synchronous bilateral breast carcinoma radiotherapy Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-14 Xingxing Zhang, Juntian Shi, Xiuxiu Wu, Liting Li, Wei Sun, Yongmei Zou, Guoquan Chen, Shaokun Wu, Song Duan
Purpose Flattening filter-free (FFF)-based volumetric modulated arc therapy (VMAT) has been shown to be feasible and significantly improves treatment efficiency and lung protection for synchronous bilateral breast irradiation (SBBI). This research compared the commonly used VMAT field arrangements using FFF beams. Methods Twenty-eight patients underwent SBBI were retrospectively enrolled to design
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Proton Therapy Equipment Installation, Upgrades and Building Design Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-14 Benjamin M Clasie, Daniel Letourneau, Marco Schwarz, Jan Seuntjens, Richard L Maughan
Abstract not available
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Match Day Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-14 Gideon J. Haber
Abstract not available
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Prospective Evaluation of the Clinical Benefits of a Novel Tattoo-less Workflow for Non-Spine Bone Stereotactic Body Radiation Therapy (SBRT): Integrating surface-guidance with triggered imaging reduces treatment time and eliminates the need for tattoos Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-08 Andrew Z. Zhou, Lauren Conway, Sarah Bartlett, Alexander Marques, Michelle Physic, Maria Czerminska, Alexander Spektor, Joseph H. Killoran, Scott Friesen, Jeremy Bredfeldt, Mai Anh Huynh
Objective Oligometastatic disease has expanded the indications for non-spine bone stereotactic body radiation therapy (NSB SBRT). We investigated whether optical surface monitoring systems (OSMS) could enable tattoo-less set up and substitute for 2D-3D or cone beam computed tomography (CBCT)-based mid-imaging in NSB SBRT. Materials/Methods OSMS was incorporated in parallel with an existing workflow
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Novel technology allowing cone beam CT in six seconds: a patient study of comparative image quality Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-07 James L. Robar, Amanda Cherpak, Robert Lee MacDonald, Abigail Yashayaeva, David McAloney, Natasha McMaster, Kenny Zhan, Slawa Cwajna, Nikhilesh Patil, Hannah Dahn
Purpose The goal of this study was to evaluate the image quality provided by a novel cone beam CT (CBCT) platform (HyperSightTM, Varian Medical Systems), a platform with enhanced reconstruction algorithms as well as rapid acquisition times. Image quality was compared to both status quo CBCT for image guidance, and to fan beam CT (FBCT) acquired on a CT simulator (CTsim). Methods In a clinical study
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Framework for Radiation Oncology Department-wide Evaluation and Implementation of Commercial AI Auto-contouring Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-05 Dominic Maes, Evan D.H. Gates, Juergen Meyer, John Kang, Bao-Ngoc Thi Nguyen, Myra Lavilla, Dustin Melancon, Emily S. Weg, Yolanda D Tseng, Andrew Lim, Stephen R. Bowen
Introduction Artificial intelligence (AI) based auto-contouring in radiation oncology has potential benefits such as standardization and time savings. However, commercial AI solutions require careful evaluation prior to clinical integration. We developed a multidimensional evaluation method to test pre-trained AI-automated contouring solutions across a network of clinics. Methods Curated data included
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Optimizing Online Adaptation Timing in the Treatment of Locally Advanced Cervical Cancer Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-02 Allen Yen, Xinran Zhong, Mu-Han Lin, Chika Nwachukwu, Kevin Albuquerque, Brian Hrycushko
Purpose/Objective: Online adaptive radiotherapy (ART) has emerged as a new treatment modality for cervical cancer. Daily online adapting improves target coverage and OAR sparing compared to traditional image-guided radiation therapy (IGRT); however, the required resources may not be feasible in a busy clinical setting. Less frequent adapting may still benefit cervical cancer patients due to large volume
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Early and intermediate treatment outcome after postoperative external beam accelerated partial breast irradiation (APBI) in early stage breast cancer patients Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-02 Anna Stenger-Weisser, Olga Unterkirhere, Christoph Glanzmann, Tino Streller, Philippe Logaritsch, Gabriela Studer
Purpose/Objectives To prospectively evaluate early and intermediate outcome after APBI in early-stage breast cancer patients. Materials/Methods Inclusion criteria were defined according to the APBI ASTRO CONSENSUS STATEMENT. The prescribed dose was 26-28 Gy in 5 fractions on 5 consecutive days. Regular follow-up visits with objective and subjective evaluation of treatment tolerance were performed after
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Association between symptom burden and early lymphatic abnormalities after regional nodal irradiation for breast cancer Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-10-31 AK Yoder, T Xu, P Youssef, SM DeSnyder, K Marqueen, L Isales, R Lin, BD Smith, WA Woodward, MC Stauder, EA Strom, MB Aldrich, SF Shaitelman
Background : Dermal backflow visualized on near-infrared fluorescence lymphatic imaging (NIRFLI) signals preclinical lymphedema that precedes the development of volumetrically-defined lymphedema. We sought to evaluate whether dermal backflow correlates with patient-reported lymphedema outcomes (PRLO) surveys in breast cancer patients treated with regional nodal irradiation (RNI). Methods and Materials
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Multi-center multi-vendor evaluation of dose volume histogram creation consistencies for eight commercial radiotherapy dosimetric systems Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-10-31 Gregory P. Penoncello, Molly M. Voss, Yu Gao, Levent Sensoy, Minsong Cao, Mark D. Pepin, Steven M. Herchko, Stanley H. Benedict, Todd A. Dewees, Yi Rong
Purpose To evaluate dose volume histogram (DVH) construction differences across eight major commercial treatment planning systems (TPSs) and dose reporting systems (DRSs) for clinically treated plans of various anatomical sites and target sizes. Materials and Methods Dose files from ten selected clinically treated plans with a hypo-fractionation, stereotactic radiotherapy prescription or sharp dose
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Multi-parametric MRI Guided Dose-Escalated Radiotherapy For Localized Prostate Cancer: A Prospective Phase II Trial Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-11-02 Nathaniel Camden, Philip Blumenfeld, Soumyajit Roy, Mudit Chowdhary, Kevin King, Stephanie Shors, Ryan Braun, Greg White, Julius Turian, Dian Wang
Purpose: To determine the late toxicity associated with dose escalation to PI-RADS III-V lesions on multiparametric MRI with an image-guided combined IMRT-SBRT approach in men with localized prostate cancer. Materials and Methods: In this phase II trial patients with localized prostate cancer with clinical tumor stage T1-T3bN0 and at least one PIRADS III-V lesion were recruited to receive 45 Gy in
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Quantification of MRI Artifacts in Carbon Fiber Reinforced Polyetheretherketone Thoracolumbar Pedicle Screw Constructs prior to Spinal Stereotactic Radiosurgery Pract. Radiat. Oncol. (IF 3.3) Pub Date : 2023-10-31 Romulo Augusto Andrade de Almeida, Amol J. Ghia, Behrang Amini, Chenyang Wang, Christopher A. Alvarez-Breckenridge, Jing Li, Laurence D. Rhines, Martin C. Tom, Robert Y. North, Thomas H. Beckham, Claudio E. Tatsui
Carbon fiber reinforced polyetheretherketone (CFRP) is a non-metallic material gaining interest in the manufacture of spinal instrumentation. The radiolucency and low magnetic susceptibility of CFRP has potential to create less interference with diagnostic imaging compared to titanium (Ti) implants. However, an objective comparison of the image artifact produced by titanium and CFRP implants has not
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