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Prognostic and predictive value of tumor deposits in advanced signet ring cell colorectal cancer: SEER database analysis and multicenter validation World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-22 Fuchao Li, Lei Liu, Qingzhao Feng, Xiaohong Wang, Fang Liu, Li Yang, Lin Miao, Weiming Wang, Guozhong Ji, Chenggong Yu
Colorectal signet-ring cell carcinoma (SRCC) is a rare cancer with a bleak prognosis. The relationship between its clinicopathological features and survival remains incompletely elucidated. Tumor deposits (TD) have been utilized to guide the N staging in the 8th edition of American Joint Committee on Cancer (AJCC) staging manual, but their prognostic significance remains to be established in colorectal
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Survival outcomes in HER2-low versus HER2-zero breast cancer after neoadjuvant chemotherapy: a meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-20 Lin-Yu Xia, Xu-Chen Cao, Yue Yu
The survival outcomes in HER2-low versus HER2-zero breast cancer (BC) after neoadjuvant chemotherapy (NACT) remain unclear. The meta-analysis was conducted to summarize current evidence about the survival outcomes in HER2-low versus HER2-zero BC. We conducted a systematic search in PubMed and EMBASE databases to identify relevant studies. A total of 14 studies with 53,714 patients were included. Overall
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Clinical implications of pediatric biliary intraepithelial neoplasia diagnosed from a choledochal cyst specimen World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-20 Sujin Gang, Hyunhee Kwon, In Hye Song, Jung-Man Namgoong
Biliary intraepithelial neoplasia (BilIN), a noninvasive precursor of cholangiocarcinoma, can manifest malignant transformation. Since cholangiocarcinoma (CCA) may progress due to chronic inflammation in the bile ducts and gallbladder, choledochal cysts are considered a precursor to CCA. However, BilIN has rarely been reported in children, to date. We reviewed medical records of patients (< 18 years
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Sarcoma of the uterine cervix: experience of a single center World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-18 Hua Yuan, Lihong Li, Ning Li, Hongwen Yao
To investigate the clinicopathological characteristics and prognosis of patients with primary sarcoma of the uterine cervix. We identified all patients with primary cervical sarcomas treated at our institution from 2002 to 2020 and analyzed the clinicopathological characteristics and prognosis. 34 patients were identified, 7 (20.6%) patients had leiomyosarcoma, 6 (17.6%) had carcinosarcoma, 5 (14.7%)
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Neoadjuvant chemotherapy does not improve survival for patients with high volume colorectal peritoneal metastases undergoing cytoreductive surgery World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-18 Mina Sarofim, Ruwanthi Wijayawardana, Nima Ahmadi, Shoma Barat, Winston Liauw, David L Morris
Colorectal peritoneal metastases (CRPM) affects 15% of patients at initial colorectal cancer diagnosis. Neoadjuvant chemotherapy (NAC) prior to cytoreductive surgery (CRS) has been demonstrated to be a safe and feasible option, however there is limited data describing its efficacy in advanced peritoneal disease. This study evaluated the effect of NAC on survival in patients with high volume CRPM undergoing
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Basal cell adenoma and basal cell adenocarcinoma of the parotid gland: clinical findings and surgical outcomes in a single-institution study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-18 Chongsoo Park, Sally Min, Joseph Kyuhyung Park, Jong-Ho Kim
Basal cell adenoma (BCA) is a rare benign tumor within the salivary glands. Basal cell adenocarcinoma (BCAC), the malignant counterpart of BCA, is also an exceedingly rare tumor with very limited clinical studies conducted. This study aims to investigate the clinical characteristics, demographics, and surgical outcomes of patients diagnosed with BCA and BCAC within the parotid gland. A retrospective
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Effect of preoperative immunonutrition on postoperative short-term clinical outcomes in patients with gastric cancer cachexia: a prospective randomized controlled trial World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-17 Junjian Yu, Antai Yuan, Qi Liu, Wei Wang, Yuqi Sun, Zequn Li, Cheng Meng, Yanbing Zhou, Shougen Cao
Although current guidelines(ESPEN guideline: Clinical nutrition in surgery and other guidelines) recommend preoperative immunonutrition for cachectic gastric cancer patients, the strength of the recommendation is weak, and the level of evidence is low. The benefits of preoperative immunonutrition still remain controversial. 112 patients with gastric cancer cachexia were enrolled in the study and randomly
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Correlation between sentinel lymph node biopsy and non-sentinel lymph node metastasis in patients with cN0 breast carcinoma: comparison of invasive ductal carcinoma and invasive lobular carcinoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-17 Calogero Cipolla, Simona Lupo, Nello Grassi, Giuseppe Tutino, Martina Greco, D’Agati Eleonora, Vittorio Gebbia, Maria Rosaria Valerio
Some studies have suggested that axillary lymph node dissection (ALND) can be avoided in women with cN0 breast cancer with 1–2 positive sentinel nodes (SLNs). However, these studies included only a few patients with invasive lobular carcinoma (ILC), so the validity of omitting ALDN in these patients remains controversial. This study compared the frequency of non-sentinel lymph nodes (non-SLNs) metastases
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Repeat cytoreductive surgery with HIPEC for colorectal peritoneal metastases: a systematic review World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-17 Mina Sarofim, Ruwanthi Wijayawardana, Nima Ahmadi, David L. Morris
Colorectal peritoneal metastases (CRPM) are present in 10–20% of patients at the time of their initial cancer diagnosis, and affects over 20% of those who develop colorectal cancer recurrence. Cytoreductive surgery (CRS) with HIPEC is firmly established as the optimal surgical treatment, but there is very little known about the benefit of repeat or iterative CRS. The aim of this review is to provide
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Impact of grade on workup of rectal neuroendocrine tumors: a retrospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-16 Akie Watanabe, Sabrina Rai, Lily Yip, Carl J. Brown, Jonathan M. Loree, Heather C. Stuart
Rectal neuroendocrine tumors (RNETs) are often discovered on screening colonoscopy. Indications for staging and definitive resection are inconsistent in current guidelines. We evaluated the role of grade in guiding staging and procedural decision-making. Patients with biopsy confirmed RNETs between 2004 and 2015 were reviewed. Baseline characteristics, staging investigations (biochemical and imaging)
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Laparoscopically harvested omental flap for immediate breast reconstruction: a retrospective single-center study of 300 cases World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-16 Hao Liu, Xiao He, Li Li, Neng-Bin Wan
The laparoscopically harvested omental flap (LHOF) has been used in partial or total breast reconstruction, but most studies on LHOF were case reports or small case series. However, the clinical feasibility and oncological safety of LHOF in oncoplastic breast surgery remains controversial. This study reported our experience applying LHOF for immediate breast reconstruction. Between June 2018 and March
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Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-16 Tom Vandaele, Jan Van Slambrouck, Patrick Schöffski, Herlinde Dumez, Birgit Weynand, Raf Sciot, Annalisa Barbarossa, An-Lies Provoost, Kristof Van de Voorde, Yves Debaveye, Sofian Bouneb, Philippe Nafteux, Laurens J. Ceulemans
Pleural neoplasms are rare and can be subdivided into pleural metastasis and primary pleural neoplasms. Non-mesothelioma primary pleural neoplasms are a diverse group of extremely rare pathologies. In this case series, we describe the presentation and management of two rare primary pleural neoplasms. A first case describes a primary pleural yolk sac tumor treated with neoadjuvant chemotherapy, extended
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Elective neck dissection versus elective neck irradiation in cT3/4N0 maxillary sinus squamous cell carcinoma: a propensity score matching analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-15 Min Chen, Hefeng Gu, Guihong Xuan, Lan Ma, Sunyu Tu, Min Li
Maxillary sinus squamous cell carcinoma (MS-SCC) is an infrequent malignancy, and determining the optimal neck management for patients with cT3/4N0 MS-SCC remains a topic of ongoing debate. The purpose of this study was to compare the prognoses and quality of life outcomes of patients who underwent either elective neck dissection (END) or elective neck irradiation (ENI) for cT3/4N0 MS-SCC. In this
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Preoperative risk factors and cumulative incidence of temporary ileostomy non-closure after sphincter-preserving surgery for rectal cancer: a meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-12 Fan He, Chenglin Tang, Fuyu Yang, Defei Chen, Junjie Xiong, Yu Zou, Dongqin Zhao, Kun Qian
Temporary ileostomy (TI) has proven effective in reducing the severity of anastomotic leakage after rectal cancer surgery; however, some ileostomies fail to reverse over time, leading to conversion into a permanent stoma (PS). In this study, we aimed to investigate the preoperative risk factors and cumulative incidence of TI non-closure after sphincter-preserving surgery for rectal cancer. We conducted
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Assessment of disease control rate and safety of sorafenib in targeted therapy for advanced liver cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-12 Daolin Zeng, Chunlin Yu, Shiyao Chen, Long Zou, Junjun Chen, Linlong Xu
The clinical efficacy and safety of sorafenib in patients with advanced liver cancer (ALC) were evaluated based on transarterial chemoembolization (TACE). 92 patients with ALC admitted to our hospital from May 2020 to August 2022 were randomly rolled into a control (Ctrl) group and an observation (Obs) group, with 46 patients in each. Patients in the Ctrl group received TACE treatment, while those
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Anatomical variants of the intercostobrachial nerve and its preservation during surgery, a systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-11 Roberto Cirocchi, Matteo Matteucci, Justus Randolph, Francesca Duro, Luca Properzi, Stefano Avenia, Bruno Amato, Ruggiero Iandoli, Giovanni Tebala, Carlo Boselli, Piero Covarelli, Paolo Sapienza
The anatomic variants of the intercostobrachial nerve (ICBN) represent a potential risk of injuries during surgical procedure such as axillary lymph node dissection and sentinel lymph node biopsy in breast cancer and melanoma patients. The aim of this systematic review and meta-analysis was to investigate the different origins and branching patterns of the intercostobrachial nerve also providing an
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Comparison of the effect of ultrasounic-harmonic scalpel and electrocautery in the treatment of axillary lymph nodes during radical surgery for breast cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-11 Yujia Tian, Lifei Han, Xiao Ma, Rui Guo, Zhuoga GeSang, Yabo Zhai, Haolin Hu
To compare the efficacy of ultrasounic-harmonic scalpel and electrocautery in the treatment of axillary lymph nodes during radical surgery for breast cancer. A prospective study was conducted in the Department of Breast Surgery, Zhongda Hospital Affiliated to Southeast University. A total of 128 patients with pathologically confirmed breast cancer who were treated by the same surgeon from July 2023
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Clinical study of the posterior gastric artery and the lymph nodes around it in patients with gastric cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-10 Kexin Wang, Haitao Duan, Maohua Wei, Liang Cao, Jian Zhang, Chi Zhang, Pin Liang
This study aims to gather and analyze the anatomical characteristics of the posterior gastric artery (PGA), investigate the presence and metastasis of lymph nodes around the PGA in patients with gastric cancer. Additionally, the study aims to analyze the relationship between the PGA and its surrounding lymph nodes and the clinicopathological features of patients with gastric cancer. This study consisted
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The therapeutic effect of radiotherapy combined with systemic therapy compared to radiotherapy alone in patients with simple brain metastasis after first-line treatment of limited-stage small cell lung cancer: a retrospective study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-10 Xinyu Gao, Tingting Liu, Min Fan, Hongfu Sun, Shixuan Zhou, Yuxin Zhou, Haolin Zhu, Ru Zhang, Zhanyuan Li, Wei Huang
We aimed to compare the therapeutic effect of radiotherapy (RT) plus systemic therapy (ST) with RT alone in patients with simple brain metastasis (BM) after first-line treatment of limited-stage small cell lung cancer (LS-SCLC). The patients were treated at a single center from January 2011 to January 2022. BM only without metastases to other organs was defined as simple BM. The eligible patients were
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Neoadjuvant pertuzumab plus trastuzumab in combination with chemotherapy for human epidermal growth factor receptor 2 positive breast cancer: a real-world retrospective single-institutional study in China World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-06 Dong-Mei Peng, Juan Li, Jia-Xin Qiu, Lin Zhao
Real-world studies on neoadjuvant dual anti-HER2 therapy combined with chemotherapy for breast cancer (BC) are scarce in China. This study aimed to evaluate the efficacy and safety of neoadjuvant dual anti-HER2 therapy combined with chemotherapy in a real-world setting. Moreover, differences in estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and
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Preservation of the celiac branch of the vagus nerve reduces the incidence of postoperative diarrhea in gastric cancer: a cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-06 Hao Guo, WeiFeng Sun, HaiTao Duan, Chi Zhang, MaoHua Wei, Pin Liang, Xiang Hu, Liang Cao
To investigate the short-term and long-term outcomes of preserving the celiac branch of the vagus nerve during laparoscopic distal gastrectomy. A total of 149 patients with prospective diagnosis of gastric cancer who underwent laparoscopic-assisted distal gastrectomy (LADG) combined with Billroth-II anastomosis and D2 lymph node dissection between 2017 and 2018 were retrospectively analyzed. The patients
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Lymphovascular invasion is associated with poor long-term outcomes in patients with pT1N0-3 or pT2-3N0 remnant gastric cancer: a retrospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-05 Shutaro Sumiyoshi, Takuma Ohashi, Takeshi Kubota, Keiji Nishibeppu, Kaho Owada, Jun Kiuchi, Hiroki Shimizu, Tomohiro Arita, Daisuke Iitaka, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Kenji Watanabe, Yoshiaki Kuriu, Atsushi Shiozaki, Hisashi Ikoma, Hitoshi Fujiwara, Nobuki Yamaoka, Eigo Otsuji
Lymphovascular invasion (LVI) is a poor prognostic factor in various malignancies. However, its prognostic effect in remnant gastric cancer (RGC) remains unclear. We examined the correlation between LVI and disease prognosis in patients with T1N0-3 or T2-3N0 RGC in whom adjuvant chemotherapy was not indicated and a treatment strategy was not established. We retrospectively analyzed patients with T1N0-3
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Preliminary comparative study of lower extremity pressure measurements under the conditions using former models and new lithotomy stirrups in rectal cancer surgery World J. Surg. Onc. (IF 3.2) Pub Date : 2024-04-03 Takayuki Ochi, Hidetoshi Katsuno, Hiroyuki Kato, Shinya Takagi, Kenji Kikuchi, Kenichi Nakamura, Tomoyoshi Endo, Kazuhiro Matsuo, Hironobu Yasuoka, Akihiro Nishimura, Akihiko Horiguchi, Zenichi Morise
This study aimed to investigate the effect of the use of new lithotomy stirrups-2 on the pressure dispersal on lower limbs, which may lead to the prevention of well-leg compartment syndrome (WLCS) and deep venous thrombosis (DVT), which are the most commonly associated adverse events with laparoscopic and robot-assisted rectal surgery. A total of 30 healthy participants were included in this study
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STIM1/SOX2 proteins are co-expressed in the tumor and microenvironmental stromal cells of pancreatic ductal adenocarcinoma and ampullary carcinoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-26 Dina Sweed, Sara Mohamed Abd Elhamed, Hayam Abdel Samie Aiad, Nermine Ahmed Ehsan, Aiat Shaban Hemida, Marwa Mohammed Dawoud
Pancreatic ductal adenocarcinoma (PDAC) and ampullary carcinoma (AAC) are lethal malignancies with modest benefits from surgery. SOX2 and STIM1 have been linked to anticancer activity in several human malignancies. This study included 94 tumor cases: 48 primary PDAC, 25 metastatic PDAC, and 21 primary AAC with corresponding non-tumor tissue. All cases were immunohistochemically stained for STIM1 and
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Clinical efficiency of three-port inflatable robot-assisted thoracoscopic surgery in mediastinal tumor resection World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-25 Hao Peng, YuanPeng He, Siqi Sheng, Maierhaba Maitiyasen, Jingfeng Li, Yvxuan Liu, Jing Chen, Xinyu Hou, Haizhu Song, Jun Yi
Aimed to assess clinical effect of three-port inflatable robot-assisted thoracoscopic surgery in mediastinal tumor resection by comparing results of the robot group with the video group. Retrospectively analyze 179 patients diagnosed with anterior mediastinal tumor from May 2017 to August 2021. Two groups were divided according to the surgical approach, including 92 cases in the RATS group and 87 cases
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Outcomes of reconstructive techniques in breast cancer using BCCT. core software World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-23 Sevgi Kurt, Ahmet Serkan İlgün, Enver Özkurt, Gürsel Soybir, Gül Alço, Çağlar Ünal, Filiz Elbüken Çelebi, Tomris Duymaz, Tuğba Kayan Tapan, Naziye Ak, Çetin Ordu, Vahit Özmen
Surgery remains a priority for breast cancer treatment. This study aimed to compare the cosmetic outcomes of oncoplastic patients who had undergone breast-conserving surgery, mini-LDF (latissimus dorsi flap), and immediate implant reconstruction using both the Japanese scale and the BCCT.core (The Breast Cancer Conservative Treatment cosmetic results software) program and to validate this program.
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Enhancing precision medicine: a nomogram for predicting platinum resistance in epithelial ovarian cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-21 Ruyue Li, Zhuo Xiong, Yuan Ma, Yongmei Li, Yu’e Yang, Shaohan Ma, Chunfang Ha
This study aimed to develop a novel nomogram that can accurately estimate platinum resistance to enhance precision medicine in epithelial ovarian cancer(EOC). EOC patients who received primary therapy at the General Hospital of Ningxia Medical University between January 31, 2019, and June 30, 2021 were included. The LASSO analysis was utilized to screen the variables which contained clinical features
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Long-term outcomes of robot-assisted versus minimally invasive esophagectomy in patients with thoracic esophageal cancer: a propensity score-matched study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-20 Toru Sakurai, Akihiro Hoshino, Kenta Miyoshi, Erika Yamada, Masaya Enomoto, Junichi Mazaki, Hiroshi Kuwabara, Kenichi Iwasaki, Yoshihiro Ota, Shingo Tachibana, Yutaka Hayashi, Tetsuo Ishizaki, Yuichi Nagakawa
Recently, robot-assisted minimally invasive esophagectomy (RAMIE) has gained popularity worldwide. Some studies have compared the long-term results of RAMIE and minimally invasive esophagectomy (MIE). However, there are no reports on the long-term outcomes of RAMIE in Japan. This study compared the long-term outcomes of RAMIE and MIE. This retrospective study included 86 patients with thoracic esophageal
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Multiple high-risk HPV infections probably associated with a higher risk of low-grade cytological abnormalities but not with high-grade intraepithelial lesions of the cervix World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-14 Tong Tong, Di Su, Qi Yang, Kun Yang, Yuqi Liu, Qun Wang, Tian Tian
For women diagnosed with HR-HPV DNA positivity in community hospitals, the necessity of investigating the potential presence of multiple HR-HPV infections upon referral to tertiary medical institutions remains unclear. In our cohort, women tested positive for HR-HPV DNA during examinations in community hospitals, were subsequently referred to tertiary medical facilities, reevaluated HR-HPV genotype
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Successful multidisciplinary treatment for synchronous advanced esophageal and cecal cancers after total gastrectomy with reconstruction by jejunal interposition World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-14 Yuta Sato, Yoshihiro Tanaka, Kazuo Yamamoto, Takeshi Horaguchi, Masahiro Fukada, Yuki Sengoku, Itaru Yasufuku, Ryuichi Asai, Jesse Yu Tajima, Shigeru Kiyama, Takazumi Kato, Katsutoshi Murase, Nobuhisa Matsuhashi
Esophageal squamous cell carcinoma is characterized by field cancerization, wherein multiple cancers occur in the esophagus, head and neck, and stomach. Synchronous esophageal and colorectal cancers are also encountered with a certain frequency. A good prognosis can be expected if the tumors in both locations can be safely and completely removed. For patients with multiple cancers that occur simultaneously
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Metastatic melanoma to small bowel: metastasectomy is supported in the era of immunotherapy and checkpoint inhibitors World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-11 Paul Wong, Andrew D. Wisneski, Katy K. Tsai, Tammy T. Chang, Kenzo Hirose, Eric K. Nakakura, Adil I. Daud, Ajay V. Maker, Carlos U. Corvera
Metastatic melanoma to the small bowel is an aggressive disease often accompanied by obstruction, abdominal pain, and gastrointestinal bleeding. With advancements in melanoma treatment, the role for metastasectomy continues to evolve. Inclusion of novel immunotherapeutic agents, such as checkpoint inhibitors, into standard treatment regimens presents potential survival benefits for patients receiving
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Renal cell carcinoma with an “uncoiling” tumor thrombus: intraoperative shift from level III to level IV World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-07 Marina Mata, Marina M. Tabbara, Angel Alvarez, Javier González, Gaetano Ciancio
The gold standard treatment for renal cell carcinoma (RCC) with tumor thrombus (TT) is complete surgical excision. The surgery is complex and challenging to the surgeon, especially with large tumor thrombus extending into the inferior vena cava (IVC) and right atrium. Traditionally, these difficult cases required the use of cardiopulmonary bypass (CPB) with or without deep hypothermic cardiac arrest
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The effect of spread through air spaces on postoperative recurrence-free survival in patients with multiple primary lung cancers World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-05 Hongsheng Xie, Shihua Dou, Xiaoxiang Huang, Yuxin Wen, Lin Yang
The purpose of the study was to investigate the effect of spread through air spaces (STAS) on the postoperative prognosis of patients with multiple primary lung cancers staged from IA to IB based on tumor size. Clinicopathological and follow-up data of 122 patients with multiple primary lung cancers diagnosed at stages IA-IB and surgically treated at the Department of Thoracic Surgery, Shenzhen people’s
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Involvement of CX3CR1+ cells appearing in the abdominal cavity in the immunosuppressive environment immediately after gastric cancer surgery World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-04 Seiji Natsuki, Mami Yoshii, Hiroaki Tanaka, Takuya Mori, Sota Deguchi, Yuichiro Miki, Tatsuro Tamura, Takahiro Toyokawa, Shigeru Lee, Kiyoshi Maeda
Gastric cancer is primarily treated by surgery; however, little is known about the changes in the intraperitoneal immune environment and the prognostic impact of surgery. Surgical stress and cancer-associated inflammation cause immune cells to mobilize into the abdominal cavity via numerous cytokines. One such cytokine, CX3CR1, has various immune-related functions that remain to be fully explained
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Application of hand-sewn esophagojejunostomy in laparoscopic total gastrectomy World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-02 Hao Gu, Weixiang Li, Lianbang Zhou
To investigate the clinical efficacy and prognostic implication of hand-sewn anastomosis in laparoscopic total gastrectomy (LTG). Retrospective analysis is adopted to the clinicopathologic data of 112 patients with gastric cancer (GC) who went through LTG in the Department of General Surgery, the Second Affiliated Hospital of Anhui Medical University between October 2020 and October 2022. Among them
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Mammographically detected breast clustered microcalcifications localized by chest thin-section computed tomography World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-29 Xinjie Liu, Yuhan Bao, Laijian Sui, Jianqiao Cao, Yidan Wang, Chao Yu, Guangdong Qiao, Yizi Cong
To explore the capability and clinical significance of chest thin-section computed tomography (CT) for localization of mammographically detected clustered microcalcifications. A total of 69 patients with 71 mammographically detected clustered microcalcifications received surgical biopsy under the guidance of mammography (MG), CT was used to localize calcifications combined with MG if calcifications
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Smartphone-based inertial measurements during Chester step test as a predictor of length of hospital stay in abdominopelvic cancer postoperative period: a prospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-28 Ananda Quaresma Nascimento, Letícia Akemi Rosa Nagata, Manuela Trindade Almeida, Vanessa Ladyanne da Silva Costa, Ana Beatriz Rocha de Marin, Victória Brioso Tavares, Geraldo Ishak, Bianca Callegari, Enzo Gabriel Rocha Santos, Givago da Silva Souza, João Simão de Melo Neto
Objective assessment of pre-operative functional capacity in cancer patients using the smartphone gyroscope during the Chester step (CST) test may allow greater sensitivity of test results. This study has investigated whether the CST is a postoperative hospital permanence predictor in cancer patients undergoing abdominopelvic surgery through work, VO2MAX and gyroscopic movement analysis. Prospective
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Meta-analysis of clinical efficacy of thoracoscopy and robotic surgery in the treatment of mediastinal tumors World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-28 Jiying Dang, Shize Sun, Zhengqi Wu, Yidong Shan, Huiling Zhang
Comparing the clinical efficacy of thoracoscopy and robotic surgery in the treatment of mediastinal tumors using meta-analysis. Computer retrieval of PubMed, Embase, The Cochrane Library, and Web of Science databases for literature comparing the clinical effects of video-assisted thoracic surgery (VATS) and robot-assisted thoracic surgery (RATS) in treating mediastinal tumors, with the retrieval time
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Efficacy and safety of direct oral anticoagulants versus low-molecular-weight heparin for thromboprophylaxis after cancer surgery: a systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-26 Hong Zhou, Ting-Ting Chen, Ling-ling Ye, Jun-Jie Ma, Jin-Hua Zhang
Direct oral anticoagulants (DOACs) used as an alternative to low-molecular-weight heparin (LMWH) for thromboprophylaxis after cancer surgery for venous thromboembolic events (VTE) remains unclear. This study aimed to investigate the efficacy and safety of DOACs versus LMWH in these patients. A search of EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science was
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The role and controversy of pelvic lymph node dissection in prostate cancer treatment: a focused review World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-26 Baonan Dong, Hui Zhan, Ting Luan, Jiansong Wang
Pelvic lymph node dissection (PLND) is commonly performed alongside radical prostatectomy. Its primary objective is to determine the lymphatic staging of prostate tumors by removing lymph nodes involved in lymphatic drainage. This aids in guiding subsequent treatment and removing metastatic foci, potentially offering significant therapeutic benefits. Despite varying recommendations from clinical practice
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Predictive accuracy of boosted regression model in estimating risk of venous thromboembolism following minimally invasive radical surgery in pharmacological prophylaxis-naïve men with prostate cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Chie Hui Leong, Sushil Rodrigues Ranjan, Anna Javed, Basim S.O. Alsaedi, Ghulam Nabi
Venous thromboembolism (VTE) is a potentially life-threatening but preventable complication after urological surgery. Physicians are faced with the challenges of weighing the risks and benefits of thromboprophylaxis given scanty evidence for or against and practice variation worldwide. The primary objective of the study was to explore the possibility of a risk-stratified approach for thromboembolism
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Is there any difference in urinary continence between bilateral and unilateral nerve sparing during radical prostatectomy? A systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Peng Xiang, Zhen Du, Di Guan, Wei Yan, Mingdong Wang, Danyang Guo, Dan Liu, Yuexin Liu, Hao Ping
In men with prostate cancer, urinary incontinence is one of the most common long-term side effects of radical prostatectomy (RP). The recovery of urinary continence in patients is positively influenced by preserving the integrity of the neurovascular bundles (NVBs). However, it is still unclear if bilateral nerve sparing (BNS) is superior to unilateral nerve sparing (UNS) in terms of post-RP urinary
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Clinical characteristics and prognostic analysis of postoperative recurrence or metastasis of low-risk gastrointestinal stromal tumors World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Lianlian Cao, Chen Lin, Yu Liu, Chao Sui, Zhaoping Li, Li Chen, Wenxian Guan, Liang Tao, Tingting Tao, Meng Wang, Feng Wang
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. This study aimed to investigate the clinical characteristics and prognosis of postoperative recurrence or metastasis in patients with low-risk stromal tumors, in order to take individualized postoperative management and treatment for patients with low-risk GISTs with relatively high recurrence. We
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Preoperative serum level of CA153 and a new model to predict the sub-optimal primary debulking surgery in patients with advanced epithelial ovarian cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Yue Jia, Yaping Jiang, Xiaoqi Fan, Ya Zhang, Kun Li, Haohan Wang, Xianling Ning, Xielan Yang
The aim of this study was to establish a preoperative model to predict the outcome of primary debulking surgery (PDS) for advanced ovarian cancer (AOC) patients by combing Suidan predictive model with HE4, CA125, CA153 and ROMA index. 76 AOC Patients in revised 2014 International Federation of Gynecology and Obstetrics (FIGO) stage III-IV who underwent PDS between 2017 and 2019 from Yunnan Cancer Hospital
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A case report of carcinoma of the papilla of Vater associated with a hyperplasia–dysplasia–carcinoma sequence by pancreaticobiliary maljunction World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-22 Takahiro Korai, Yasutoshi Kimura, Kazunori Watanabe, Siew-Kee Low, Masafumi Imamura, Minoru Nagayama, Kazuharu Kukita, Takeshi Murakami, Toru Kato, Yuta Kondo, Daisuke Kyuno, Taro Sugawara, Ayako Murota, Yujiro Kawakami, Yoshiharu Masaki, Hiroshi Nakase, Ichiro Takemasa
Pancreaticobiliary maljunction (PBM) is a known risk factor for biliary tract cancer. However, its association with carcinoma of the papilla of Vater (PVca) remains unknown. We report a case with PVca that was thought to be caused by the hyperplasia–dysplasia–carcinoma sequence, which is considered a mechanism underlying PBM-induced biliary tract cancer. A 70-year-old woman presented with white stool
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Laparoscopic versus laparotomic surgical treatment in apparent stage I ovarian cancer: a multi-center retrospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-22 Jing Zhang, Meiyan Li, Lan Feng, Yinjun Zhai, Lin Wang, Yuancao Chen
Laparoscopic treatment shows non-inferior survival outcomes and better surgical outcomes in apparent stage I ovarian cancer (OC) in some studies but has not been well defined. We conducted a retrospective study of patients with apparent stage I OC treated in two hospitals between 2012 and 2022. The surgical and oncologic outcomes were evaluated between patients receiving laparoscopic and laparotomic
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Association of preoperative muscle-adipose index measured by computed tomography with survival in patients with esophageal squamous cell carcinoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-22 Danqi Qian, Peipei Shen, Jiahao Zhu, Shengjun Ji, Yan Kong
Conventional nutritional metrics are closely associated with the prognosis of patients with radically resected esophageal squamous cell carcinoma (ESCC). Nevertheless, the prognostic implications of muscle and adipose tissue composite indexes in ESCC remain unknown. We retrospectively analyzed clinicopathological data of 304 patients who underwent resected ESCC. To obtain measurements of the muscle
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Radiation-induced cutaneous vasculopathy of the breast: a rare case report World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-21 Hilde Van Parijs, Yves Sinove, Marilyn Carprieaux, Mark De Ridder
Radiation therapy is often indicated as part of the treatment for breast cancer and is therefore used frequently worldwide. Vasculopathy is a general term used to describe any condition that affects blood vessels. We present a case report of a patient who presented with vasculopathy as a rare late side effect of radiation therapy to the breast. This 66-year-old woman was initially treated with breast-conserving
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Younger patients with colorectal cancer may have better long-term survival after surgery: a retrospective study based on propensity score matching analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-21 Weihao Liao, Yuanxi Li, Yuheng Zou, Qinchen Xu, Xiaodong Wang, Li Li
The relationship between postoperative long-term prognosis and age in colorectal cancer patients remains controversial. The purpose of this study based on a Chinese CRC cohort is to determine the disparity in long-term survival outcomes between younger and older colorectal cancer (CRC) patients after surgery using a propensity score matching (PSM). Data for this study was derived from the CRC cohort
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Survival analysis of laparoscopic surgery and open surgery for hilar cholangiocarcinoma: a retrospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-19 Yaolin Yin, Jilin Tao, Yin Xian, Junhao Hu, Yonghe Li, Qiang Li, Yongfu Xiong, Yi He, Kun He, Jingdong Li
This study compared the clinical efficacy and safety of laparoscopic versus open resection for hilar cholangiocarcinoma (HCCA) and analyzed potential prognostic factors. The study included patients who underwent HCCA resection at our center from March 2012 to February 2022. Perioperative complications and postoperative prognosis were compared between the laparoscopic surgery (LS) and open surgery (OS)
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C-Myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-19 Christian Lang, Zsolt Megyesfalvi, Andras Lantos, Felicitas Oberndorfer, Mir Alireza Hoda, Anna Solta, Bence Ferencz, Janos Fillinger, Anna Solyom-Tisza, Alessandro Saeed Querner, Felix Egger, Kristiina Boettiger, Thomas Klikovits, Gerald Timelthaler, Ferenc Renyi-Vamos, Clemens Aigner, Konrad Hoetzenecker, Viktoria Laszlo, Karin Schelch, Balazs Dome
By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the expression pattern and prognostic relevance of these oncogenic proteins in an international cohort of surgically resected SCLC tumors. Clinicopathological data and surgically
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Comparison of liver resection and radiofrequency ablation in long-term survival among patients with early-stage hepatocellular carcinoma: a meta-analysis of randomized trials and high-quality propensity score-matched studies World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-19 Lingbo Hu, Jiangying Lin, Aidong Wang, Xingpeng Shi, Yingli Qiao
Whether radiofrequency ablation (RFA) and liver resection (LR) are comparable treatments for early-stage hepatocellular carcinoma (HCC) is controversial. We conducted this study to provide ample clinical evidence for the argument. The PubMed, Embase, Web of Science, and Cochrane Library databases were systematically searched to identify randomized controlled trials (RCTs) and propensity score-matched
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A MRI radiomics-based model for prediction of pelvic lymph node metastasis in cervical cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-17 Tao Wang, Yan-Yu Li, Nan-Nan Ma, Pei-An Wang, Bei Zhang
Cervical cancer (CC) is a common malignancy of the female reproductive tract, and preoperative prediction of lymph node metastasis (LNM) is essential. This study aims to design and validate a magnetic resonance imaging (MRI) radiomics-based predictive model capable of detecting LNM in patients diagnosed with CC. This retrospective analysis incorporated 86 and 38 CC patients into the training and testing
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Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following laparoscopic radical gastrectomy: an open-label, randomized, controlled, non-inferiority trial World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-15 Zhimin Lin, Zhongbiao Chen, Yongliang Li
In patients undergoing laparoscopic radical gastrectomy, the use of subcostal transversus abdominis plane block (STAPB) for completely opioid-free postoperative pain management lacks convincing clinical evidence. This study included 112 patients who underwent laparoscopic radical gastrectomy at the 900TH Hospital of the Joint Logistics Support Force from October 2020 to March 2022. Patients were randomly
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Surgical outcomes after reoperation for patients with recurrent presacral tumors: a retrospective study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-15 Rui Li, Zhiyuan Yu, Jiahu Ye, Xin Liu, Peiyu Li, Xudong Zhao
Relevant reports on the surgical resection and prognosis of recurrent presacral tumors are limited. The objective of this study was to explore the outcomes associated with surgical resection of recurrent presacral tumors. The data of patients with recurrent presacral tumors who received surgical resection in our hospital between June 2009 and November 2018 were retrospectively analyzed. Thirty-one
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Advances in the assessment of cosmetic outcomes, sensory alteration in surgical areas, and health-related quality of life of endoscopic thyroidectomy World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-13 Di Zhou, Zeyu Zhang, Xiaolin Dou, Fada Xia, Xinying Li
Endoscopic thyroidectomy has been preliminarily proven effective and safe for thyroid diseases. The cosmetic outcomes and life quality are critical contents of postoperative assessment. This review will primarily focus on the assessment methods and results related to cosmetic outcomes, sensory alteration of surgical area, and quality of life following endoscopic thyroidectomy. A comprehensive search
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Presurgical computed tomography-guided localization of lung ground glass nodules: comparing hook-wire and indocyanine green World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-10 Rui Han, Long-Fei Wang, Fei Teng, Jia Lin, Yu-Tao Xian, Yun Lu, An-Le Wu
Presurgical computed tomography (CT)-guided localization is frequently employed to reduce the thoracotomy conversion rate, while increasing the rate of successful sublobar resection of ground glass nodules (GGNs) via video-assisted thoracoscopic surgery (VATS). In this study, we compared the clinical efficacies of presurgical CT-guided hook-wire and indocyanine green (IG)-based localization of GGNs
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Case report of penile squamous cell carcinoma continuous treatment with BRCA2 mutation World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-09 Qing Zhang, Yaping Li, Yanrui Zhang, Zhiping Deng, Yi Ding
Penile squamous cell carcinoma (PSCC) is a highly aggressive malignancy with a poor prognosis. BRCA1/2 mutations are associated with impaired DNA double-strand break repair and are among the common mutations in penile cancer, potentially paving the way for poly ADP-ribose polymerase inhibitor therapy. We report a 65-year-old male with PSCC who progressed to thigh metastasis at 10 months after partial
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Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-09 Yawei Li, Hang Su, Kaidong Liu, Zhangxiang Zhao, Yuquan Wang, Bo Chen, Jie Xia, Huating Yuan, De-Shuang Huang, Yunyan Gu
TMPRSS2-ERG (T2E) fusion is highly related to aggressive clinical features in prostate cancer (PC), which guides individual therapy. However, current fusion prediction tools lacked enough accuracy and biomarkers were unable to be applied to individuals across different platforms due to their quantitative nature. This study aims to identify a transcriptome signature to detect the T2E fusion status of
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Preoperative predictors for non-resectability in perihilar cholangiocarcinoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-07 Carlos Constantin Otto, Anna Mantas, Lara Rosaline Heij, Daniel Heise, Maxime Dewulf, Sven Arke Lang, Tom Florian Ulmer, Edgar Dahl, Philipp Bruners, Ulf Peter Neumann, Jan Bednarsch
Explorative laparotomy without subsequent curative-intent liver resection remains a major clinical problem in the treatment of perihilar cholangiocarcinoma (pCCA). Thus, we aimed to identify preoperative risk factors for non-resectability of pCCA patients. Patients undergoing surgical exploration between 2010 and 2022 were eligible for the analysis. Separate binary logistic regressions analyses were