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Therapeutic bronchoscopy for malignant central airway obstructions caused by non‐bronchogenic cancers: Results from the EpiGETIF registry Respirology (IF 6.9) Pub Date : 2024-04-18 Clément Daigmorte, Daniela Usturoi, Clément Fournier, Frederic Wallyn, Christine Lorut, Valentin Héluain, Julien Mazières, Julien Legodec, Bruno Escarguel, Thomas Egenod, Laurent Cellerin, Nicolas Favrolt, Samy Lachkar, Adrian Crutu, Amandine Briault, Christophe Gut‐Gobert, Valerian Bourinet, Juliette Camuset, Perrot Loïc, Pascal Schlossmacher, Michele Porzio, Antoine Luchez, Jean‐Michel Vergnon, Marie‐Christelle
Background and ObjectiveLittle is known about malignant central airway obstruction (MCAO) complicating the metastatic spread of non‐bronchogenic solid cancers (NBC) and their bronchoscopic management. This study aimed to describe the epidemiology of this population and determine prognostic factors before therapeutic bronchoscopy (TB).MethodsIn this multicenter study using the EpiGETIF registry, we
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Home monitoring to detect progression of interstitial lung disease: A prospective cohort study Respirology (IF 6.9) Pub Date : 2024-04-08 Malik A. Althobiani, Yatharth Ranjan, Anne-Marie Russell, Joseph Jacob, Michele Orini, Heet Sankesara, Pauline Conde, Zulqarnain Rashid, Richard J. B. Dobson, John R. Hurst, Joanna C. Porter, Amos A. Folarin
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Surgical lung biopsy for Idiopathic Pulmonary Fibrosis: Is the risk–benefit ratio changing Respirology (IF 6.9) Pub Date : 2024-04-03 Ian N. Glaspole, Lauren K. Troy
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Systemic lupus erythematosus: Adding another piece to the connective tissue disease-associated interstitial lung disease puzzle Respirology (IF 6.9) Pub Date : 2024-04-02 Yet H. Khor
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Thoracic Society of Australia and New Zealand position statement: The safe clinical use of sputum induction for bio-sampling of the lower airways in children and adults Respirology (IF 6.9) Pub Date : 2024-03-31 André Schultz, Sathya Balaguruswamy, Ruth Dentice, Claudia C. Dobler, James Geake, Peter Gibson, Patricia Goulter, Lata Jayaram, Pamela J. Laird, Peter G. Middleton, Helen Seale
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Strength in data and collaboration: The EpiGETIF registry Respirology (IF 6.9) Pub Date : 2024-03-28 Michael Brown, Phan Nguyen
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Effect of complicated, untreated and uncontrolled diabetes and pre‐diabetes on treatment outcome among patients with pulmonary tuberculosis Respirology (IF 6.9) Pub Date : 2024-03-28 Kyung Hoon Kim, Hyung Woo Kim, Yong Hyun Kim, Yeonhee Park, Sung Soo Jung, Jin Woo Kim, Jee Youn Oh, Heayon Lee, Sung Kyoung Kim, Sun‐Hyung Kim, Jiwon Lyu, Yousang Ko, Sun Jung Kwon, Yun‐Jeong Jeong, Do Jin Kim, Hyeon‐Kyoung Koo, Yangjin Jegal, Sun Young Kyung, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim, Jinsoo Min
Background and ObjectivePatients with tuberculosis and diabetes have a higher risk of unfavourable anti‐tuberculosis treatment outcomes. In the present study, we aimed to evaluate the effects of various diabetes statuses on the outcomes of patients with pulmonary tuberculosis.MethodsAmong the patients with pulmonary tuberculosis enrolled in the Korea Tuberculosis Cohort (KTBC) registry and the multicentre
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Letter from Canada: Global warming and wildfire smoke pollution emerging as major threats to respiratory health Respirology (IF 6.9) Pub Date : 2024-03-28 Allison Michaud, Richard Leigh
Like in many parts of the world, Canada has seen a dramatic increase in the number and size of wildfires over the last several summers, with deleterious effects on health, ecosystems and indigenous communities. The summer of 2023 was Canada's most destructive wildfire season ever recorded, with at least 6623 fires destroying over 18.4 million hectares of land (Figure 1).1 This shattered the previous
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Optimal clinical practice in IPF and PPF: Integrating the scientific ethos and clinical reasoning Respirology (IF 6.9) Pub Date : 2024-03-27 Athol U. Wells
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Reply to: Optimal clinical practice in IPF and PPF: Integrating scientific ethos and clinical reasoning Respirology (IF 6.9) Pub Date : 2024-03-27 John A. Mackintosh, Gregory Keir, Tamera J. Corte
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An additional mechanism enhancing exercise tolerance in interstitial lung disease with high‐flow nasal cannula Respirology (IF 6.9) Pub Date : 2024-03-26 Keisuke Tomii
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Reply to: ‘Is continuous positive airway pressure truly superior to high-flow nasal cannula in managing acute hypoxemic respiratory failure?’ Respirology (IF 6.9) Pub Date : 2024-03-25 Kazuma Nagata, Toshiki Yokoyama, Ryosuke Tsugitomi
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Is continuous positive airway pressure truly superior to high-flow nasal cannula in managing acute hypoxemic respiratory failure? Respirology (IF 6.9) Pub Date : 2024-03-25 Toshiro Goto, Yuki Kataoka
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Retraction Respirology (IF 6.9) Pub Date : 2024-03-22
Retraction: Rajagopalan, P., Ahmed, K. (2022) TP 075. Does lung cancer multidisciplinary meetings under diagnose emphysema? [Abstract] Respirology, v 21.S1: 132. https://doi.org/10.1111/resp.14226 Rajagopalan, P., Ahmed, K. (2022) TP 076. Reduction in rate of exacerbations of COPD during COVID-19 pandemic. [Abstract] Respirology, v 21.S1: 133. https://doi.org/10.1111/resp.14226. Rajagopalan, P., Ahmed
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The United Nations Framework Convention on Climate Change (UNFCCC) 28th Conference of the Parties, Dubai (COP28): Implications for lung disease Respirology (IF 6.9) Pub Date : 2024-03-18 Paul J. Beggs, Camile Oliveira, Catharina Giudice
Climate change is the greatest health threat of the 21st century. Among the broad array of diseases impacted by climate change, respiratory diseases feature prominently. Increases in temperature and other changes in climate can increase air pollution, particularly ozone and particulate matter,1, 2 which, in turn, is associated with increase in all-cause mortality, respiratory disease and lung cancer
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Chronic interstitial lung disease associated with systemic lupus erythematosus: A multicentric study of 89 cases Respirology (IF 6.9) Pub Date : 2024-03-17 Lou Deneuville, Arthur Mageau, Marie Pierre Debray, Karim Sacre, Nathalie Costedoat-Chalumeau, Eric Hachulla, Yurdagul Uzunhan, Erwan Le Tallec, Jacques Cadranel, Sylvain Marchand Adam, David Montani, Martine Rémi-Jardin, Martine Reynaud-Gaubert, Gregoire Prevot, Guillaume Beltramo, Bruno Crestani, Vincent Cottin, Raphael Borie
Chronic interstitial lung disease (ILD) occurs rarely with systemic lupus erythematosus (SLE) as compared with other connective tissue diseases. This multicentric retrospective study of patients with SLE-ILD from the OrphaLung and French SLE networks during 2005–2020 aimed to describe the characteristics of patients with SLE-ILD and analyse factors associated with prognosis.
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Clinical trials and clinical trials networks Respirology (IF 6.9) Pub Date : 2024-03-18 Ary Serpa Neto, Rinaldo Bellomo
Key points Clinical trials dominate the academic and evidence-based landscape. There is no credible alternative to clinical trials. Clinical trials address issues where there is equipoise. Equipoise implies relatively limited size effects. Limited size effects imply the need for large populations. Large populations imply the need for clinical trial networks. National trial networks are very successful
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Efficacy of varenicline or bupropion and its association with nicotine metabolite ratio among smokers with COPD Respirology (IF 6.9) Pub Date : 2024-03-18 Rui Qin, Zhao Liu, An‐qi Cheng, Xin‐mei Zhou, Zheng Su, Zi‐yang Cui, Jin‐xuan Li, Xiao‐wen Wei, Liang Zhao, Kian Fan Chung, Dan Xiao, Chen Wang
Background and objectiveNicotine metabolic ratio (NMR) has been associated with nicotine metabolism and smoking characteristics. However, there are few studies on the potential association between NMR and smoking cessation efficacy in smokers with chronic obstructive pulmonary disease (COPD) in China or elsewhere.MethodsThis study was a stratified block randomized controlled trial for smoking cessation
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Effect of off‐label targeted drugs on long‐term survival in chronic thromboembolic pulmonary hypertension: Insights from a national multicentre prospective registry Respirology (IF 6.9) Pub Date : 2024-03-18 Wanying Xia, Yuling Qian, Yangyi Lin, Ruilin Quan, Yuanhua Yang, Zhenwen Yang, Hongyan Tian, Shengqing Li, Jieyan Shen, Yingqun Ji, Qing Gu, Huijun Han, Changming Xiong, Jianguo He
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Transforming recruitment to clinical trials in COPD Respirology (IF 6.9) Pub Date : 2024-03-18 Tanya Patrick, John R. Hurst
To paraphrase Sir Martin Landray—who co-led the COVID-19 RECOVERY trial (https://www.ndph.ox.ac.uk/team/martin-landray)—‘for such a common disease, it's remarkably difficult to recruit people with chronic obstructive pulmonary disease to clinical trials’. This got us thinking. Why is that so, and what can we do about it? First off, it should be said that recruitment to any clinical trial is challenging—our
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The impact of hiatus hernia in hypersensitivity pneumonitis Respirology (IF 6.9) Pub Date : 2024-03-13 David A. Heriot, Carmel J. W. Stock, Zain-Ul-Abideen Mumtaz, R. Gisli Jenkins, Felix Chua, Phillip L. Molyneaux, Anand Devaraj, Vasilis Kouranos, Athol U. Wells, Elizabetta A. Renzoni, Simon P. G. Padley, Sujal R. Desai, Peter M. George
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Use of spirometry to detect airflow obstruction Respirology (IF 6.9) Pub Date : 2024-03-04 Chi Chiu Leung
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Therapeutic bronchoscopy for malignant central airway obstruction: Introduction to the EpiGETIF registry Respirology (IF 6.9) Pub Date : 2024-03-03 Nicolas Guibert, Pascalin Roy, Lyria Amari, Julien Legodec, Bruno Escarguel, Clément Fournier, Frederic Wallyn, Laurent Cellerin, Christine Lorut, Daniela Usturoi, Thomas Egenod, Nicolas Favrolt, Pascal Schlossmacher, Valerian Bourinet, Perrot Loïc, Samy Lachkar, Juliette Camuset, Amandine Briault, Romain Kessler, Christophe Gut-Gobert, Gilles Mangiapan, Nicolas Carnot, Eric Briens, Adrian Crutu, Armelle
EpiGETIF is a web-based, multicentre clinical database created in 2019 aiming for prospective collection of data regarding therapeutic rigid bronchoscopy (TB) for malignant central airway obstruction (MCAO).
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Up-to-date data on NightLase laser treatment of snoring for discussion Respirology (IF 6.9) Pub Date : 2024-03-05 Peter R. Dawson
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Reply: Up-to-date data on NightLase laser treatment of snoring for discussion Respirology (IF 6.9) Pub Date : 2024-03-05 Leba M. Sarkis, Andrew C. Jones, Andrew Ng, Christopher Pantin, Sarah L. Appleton, Stuart G. MacKay
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Impact of surgical lung biopsy on lung function and survival in patients with idiopathic pulmonary fibrosis in a multi‐centre registry cohort Respirology (IF 6.9) Pub Date : 2024-03-04 Veronica Marcoux, Stacey D. Lok, Prosanta Mondal, Deborah Assayag, Jolene H. Fisher, Shane Shapera, Julie Morisset, Hélène Manganas, Charlene D. Fell, Nathan Hambly, P. Gerard Cox, Martin Kolb, Andrea S. Gershon, Teresa To, Mohsen Sadatsafavi, Nasreen Khalil, Alyson W. Wong, Pearce G. Wilcox, Christopher J. Ryerson, Thao Vu, Kerri A. Johannson
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The TSANZ and Lung Foundation Australia 2023 landscape survey of lung cancer care across Australia and Aotearoa New Zealand Respirology (IF 6.9) Pub Date : 2024-03-03 Jessica Nash, Tracy Leong, Paul Dawkins, Emily Stone, Henry Marshall, Fraser Brims
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The long and winding road—Where to now for asthma? Respirology (IF 6.9) Pub Date : 2024-02-29 Christine R. Jenkins, Phillip Bardin
Readers might reasonably ask, why did we choose the title ‘The Future of Asthma’ for this series? This may not seem an obvious question given that we now have a range of treatments that can address the spectrum of asthma severity, along with a suite of self-management, control assessment tools and educational approaches that are necessary adjuncts to available therapies and address the multidimensional
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Recommendations from The Medical Education Editor Respirology (IF 6.9) Pub Date : 2024-02-27 Mark Lavercombe
It is a privilege to highlight several articles published in Respirology of continuing educational value, and the following three papers were selected for this quarterly editorial: Bianquis C, Rolland-Debord C, Rivals I, Similowski T, Morélot-Panzini C. Dyspnoea relief as an inherent benefit of high flow nasal cannula therapy: a laboratory randomized trial in healthy humans. https://onlinelibrary.wiley
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Chronic cough: New guidelines, new approaches and new treatments Respirology (IF 6.9) Pub Date : 2024-02-27 Richard Turner, Stuart Mazzone, Surinder Birring
The end of 2023 brought with it updated national clinical statements on the management on chronic cough from both Australia and the United Kingdom.1, 2 Both were long in coming, being published 13 and 17 years since their predecessor documents, respectively. Much has changed in the intervening time in the understanding of cough, necessitating and informing the statement updates. Chronic cough in adults
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Smoking, respiratory symptoms, lung function and life expectancy: A longitudinal study of ageing Respirology (IF 6.9) Pub Date : 2024-02-26 Kate Petrie, Michael J. Abramson, Johnson George
Background and ObjectivePrognostic indices have been developed to predict various outcomes, including mortality. These indices and hazard ratios may be difficult for patients to understand. We investigated the association between smoking, respiratory symptoms and lung function with remaining life expectancy (LE) in older adults.MethodsData were from the 2004/05 English Longitudinal Study of Ageing
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Enhancing exercise tolerance in interstitial lung disease with high-flow nasal cannula oxygen therapy: A randomized crossover trial Respirology (IF 6.9) Pub Date : 2024-02-22 Yorihide Yanagita, Shinichi Arizono, Koshi Yokomura, Kumiko Ito, Hikaru Machiguchi, Yuichi Tawara, Norimasa Katagiri, Yuki Iida, Eiji Nakatani, Takako Tanaka, Ryo Kozu
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Oxygen therapy could improve survival in patients with early desaturation in the 6-minute walk test: A post hoc analysis Respirology (IF 6.9) Pub Date : 2024-02-25 Ignacio García-Talavera, Juan Marco Figueira-Gonçalves, Cristobal Esteban, Rafael Golpe, Silvia García-Talavera, Carlos Amado, Amaia Aramburu, Lina I. Pérez-Méndez, Alicia Conde-Martel
Long-term domiciliary oxygen therapy (LTDOT) in patients with chronic obstructive pulmonary disease (COPD) has been shown to increase survival when associated with severe hypoxaemia at rest,1, 2 but not when accompanied by moderate hypoxaemia at rest.3, 4 However, the benefits of LTDOT in patients with COPD and moderate hypoxaemia at rest and with desaturation during exercise are unknown, although
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Using change in 6-minute walk distance to predict survival in progressive pulmonary fibrosis: A promising measure in need of precision Respirology (IF 6.9) Pub Date : 2024-02-25 Anne E. Holland, Leona Dowman
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What makes asthma characterized by airway eosinophilia become severe? Respirology (IF 6.9) Pub Date : 2024-02-25 Thomas Rothe, Niki Ubags, Christophe von Garnier
Eosinophilic type-2 inflammation is a feature of both allergic early-onset asthma (AEOA) and eosinophilic adult-onset asthma (EAOA). Normally, inhaled corticosteroids (ICS) provide a successful clinical response at moderate dosing, but patients with severe asthma may require high-dose ICS and sometimes even daily oral corticosteroids (OCS) to achieve asthma control. However, despite optimized inhaled
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Changing trends in mesothelioma: Important lessons for an occupational disease registry Respirology (IF 6.9) Pub Date : 2024-02-25 Hayley Barnes, Ryan F. Hoy
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Let's talk about obesity in respiratory disease Respirology (IF 6.9) Pub Date : 2024-02-23 Vanessa Marie McDonald
Obesity is a chronic and relapsing condition where weight loss is often associated with regain of weight over time.1 The prevalence of obesity is increasing, and it is now referred to as a global pandemic.2 Prevalence data suggest that by 2035, over 4 billion people worldwide may be living with overweight (BMI ≥25 kg/m2) or obesity, compared with the 2020 prevalence of 2.6 billion.3 The prevalence
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Combined effect of changes in NO2, O3, PM2.5, SO2 and CO concentrations on small airway dysfunction Respirology (IF 6.9) Pub Date : 2024-02-20 Hyun Woo Lee, Hyo Jin Lee, Sohee Oh, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim
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Asthma in children—What's in the future Respirology (IF 6.9) Pub Date : 2024-02-21 Peter Neils Le Souëf
Key points Asthma treatment has been largely unchanged for 50 years. New mechanistic studies promise to lead to the next major advances. Immunomodulation to enhance interferon responses shows great promise. Climate change affects asthma already and is going to get worse. Advances in asthma therapy are long overdue, as little has changed since inhaled corticosteroids were introduced 50 years ago. Biologics
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Local knowledge: Every surfer knows the feeling Respirology (IF 6.9) Pub Date : 2024-02-20 Peter Gerard Gibson
Why is it so hard for our patients to receive the proven benefits of therapies and management approaches? You would think it should be an easy road from a positive randomized controlled trial to implementation of an effective treatment approach. But this gap between what we know works and what we actually do, ‘the know-do gap’, is large and cavernous. There is a key element, that is seldom recognized
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Next-generation sequencing using tissue specimen collected with a 1.1 mm-diameter cryoprobe in patients with lung cancer Respirology (IF 6.9) Pub Date : 2024-02-20 Mi-Hyun Kim, Soo Han Kim, Geewon Lee, Jeongha Mok, Min Ki Lee, Ju Sun Song, Jung Seop Eom
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Diabetes and lung function: Linked, but how? Respirology (IF 6.9) Pub Date : 2024-02-20 Alan James
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Siloed thinking is limiting health care delivery Respirology (IF 6.9) Pub Date : 2024-02-20 Paul N. Reynolds
The cost of healthcare is an ever-present challenge in all health systems globally. Those of us living in developed countries face this problem in our day-to-day work much less frequently than those in developing economies, but every so often situations emerge that remind us of the realities of limited resources. This is especially the case when new therapies come onto the market, with the need to
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Lung ultrasound is a promising screening tool to rule out interstitial lung disease in patients with rheumatoid arthritis Respirology (IF 6.9) Pub Date : 2024-02-19 M. Otaola, F. Paulin, M. Rosemffet, J. Balcazar, M. Perandones, P. Orausclio, T. Cazenave, S. Rossi, S. Marciano, E. Schneeberger, G. Citera
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Low bleeding rates following transbronchial lung cryobiopsy in unclassifiable interstitial lung disease Respirology (IF 6.9) Pub Date : 2024-02-14 John Taverner, Carmen M. Lucena, Justin L. Garner, Christopher M. Orton, Andrew G. Nicholson, Sujal R. Desai, Athol U. Wells, Pallav L. Shah
Bronchoscopic transbronchial lung cryobiopsy (TBLC) is a guideline-endorsed alternative to surgical lung biopsy for tissue diagnosis in unclassifiable interstitial lung disease (ILD). The reported incidence of post-procedural bleeding has varied widely. We aimed to characterize the incidence, severity and risk factors for clinically significant bleeding following TBLC using an expert-consensus airway
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Respiratory health effects of cannabis—How should we respond to liberalization of cannabis laws? Respirology (IF 6.9) Pub Date : 2024-02-12 Robert J. Hancox
Key points Liberalization of cannabis laws is likely to lead to increasing use among some people. Cannabis is a potent cause of symptomatic bronchitis. Quitting it improves symptoms. Some heavy cannabis users develop severe bullous lung disease. Although cannabis changes lung function, the effects appear different to tobacco and there is insufficient evidence that this causes emphysema or chronic obstructive
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Similarities and differences of interstitial lung disease associated with pathogenic variants in SFTPC and ABCA3 in adults Respirology (IF 6.9) Pub Date : 2024-02-12 Rémi Diesler, Marie Legendre, Salim Si-Mohamed, Pierre-Yves Brillet, Lidwine Wemeau, Effrosyni D. Manali, Frédéric Gagnadoux, Sandrine Hirschi, Gwenaël Lorillon, Martine Reynaud-Gaubert, Vanessa Bironneau, Elodie Blanchard, Arnaud Bourdin, Stéphane Dominique, Aurélien Justet, Julie Macey, Sylvain Marchand-Adam, Hélène Morisse-Pradier, Hilario Nunes, Spyros A. Papiris, Julie Traclet, Ibrahim Traore
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Blowing in the wind—Tobacco control legislation Respirology (IF 6.9) Pub Date : 2024-02-08 Natasha Smallwood
As I was contemplating what to write about for this reflection, I was tempted to highlight the increasing tendency to incorporate song titles or lyrics into the titles of articles in respiratory medicine journals. This can be a creative way to engage readers' attention while conveying the essence of the research. And this year, we have had some rather amusing attempts to capture the imagination, with
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Cone-beam CT imaging for robotic navigation bronchoscopy Respirology (IF 6.9) Pub Date : 2024-02-07 David Fielding, Erik H. F. M. van der Heijden
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Use of 6-minute walk distance to predict lung transplant-free survival in fibrosing non-IPF interstitial lung diseases Respirology (IF 6.9) Pub Date : 2024-02-06 Umberto Zanini, Fabrizio Luppi, Karina Kaur, Niccolò Anzani, Giovanni Franco, Giovanni Ferrara, Meena Kalluri, Marco Mura
The identification of progression in patients with fibrosing non-idiopathic pulmonary fibrosis (IPF) interstitial lung diseases (ILDs) represents an ongoing clinical challenge. Lung function decline alone may have significant limitations in the detection of clinically significant progression. We hypothesized that longitudinal changes of 6-min walk distance (6MWD) from baseline, simultaneously considered
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Breaking the spiral: How negative mood can fuel exertional breathlessness in people with chronic obstructive pulmonary disease Respirology (IF 6.9) Pub Date : 2024-02-01 Amy Pascoe, Natasha Smallwood
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C-reactive protein as a candidate biomarker in fibrotic interstitial lung disease Respirology (IF 6.9) Pub Date : 2024-01-31 Vincent Cottin, Claudia Valenzuela
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Increased exacerbations of bronchiectasis following recovery from mild COVID-19 in patients with non-cystic fibrosis bronchiectasis Respirology (IF 6.9) Pub Date : 2024-01-30 Wang Chun Kwok, James Chung Man Ho, Terence Chi Chun Tam, Mary Sau Man Ip, David Chi Leung Lam