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YiQi GuBen capsule alleviates OVA-induced asthma through improving mitochondrial dysfunction J. Asthma (IF 1.9) Pub Date : 2024-04-22 Xiaoting Ren, Yibu Kong, Hongjun Yu, Aiai Dong, Yongji Wang, Lina Wei, Yongfu Song, Zhongtian Wang, Lie Wang, Yinan Guo, Liping Sun
Objective: This study aims to explore the effect of YiQi GuBen capsule on improving mitochondrial dysfunction in an animal model of asthma.Methods: The mice (n = 8) were divided into four groups in...
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Machine Learning and Bioinformatics Approaches to Identify the Candidate Biomarkers in Severe Asthma J. Asthma (IF 1.9) Pub Date : 2024-04-22 Fuying Zhang, Xiang Weng, Jiabao Zhu, Qin Tang, Mingsheng Lei, Weimin Zhou
Severe asthma is characterized by a poor level of control that severely affects the patient's life and prognosis. However, the underlying pathogenic mechanisms remain unknown. Here, we identified d...
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Spontaneous pneumomediastinum and pneumopericardium in a young male with asthma J. Asthma (IF 1.9) Pub Date : 2024-04-19 Ivy M Fan, Sarah Goh, Joe Choi, Daniel J Tan
Introduction: Spontaneous pneumomediastinum with pneumopericardium is an uncommon clinical entity. Case Study: Here, we report the case of a 23-year-old male with asthma who presented with acute ch...
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Mounier-Kuhn Syndrome in poorly controlled asthma J. Asthma (IF 1.9) Pub Date : 2024-04-19 Marta Solís García, Carolina Cisneros Serrano, Ana Sofía Martín Hernández, Jose María Eiros Bachiller, Celeste Marcos
Mounier-Kuhn syndrome or tracheobronchomegaly, is a rare condition that consists of abnormal dilation of the trachea and main bronchi due to a pathological arrangement of smooth muscle fibers in th...
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Acoustic biomarkers in asthma: a systematic review J. Asthma (IF 1.9) Pub Date : 2024-04-18 Karolina Wieczorek, Sachin Ananth, Diana Valazquez-Pimentel
Current monitoring methods of asthma, such as peak expiratory flow testing, have important limitations. The emergence of automated acoustic sound analysis, capturing cough, wheeze, and inhaler use,...
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Urinary Metabolomic Profiles Uncover Metabolic Pathways in Children with Asthma J. Asthma (IF 1.9) Pub Date : 2024-04-18 Sainan Jiang, Yiting Zhou, Jianlong Gao, Siyi Jin, Genli Pan, Yuan Jiang
Objective: The prevalence of asthma has gradually increased worldwide in recent years, which has made asthma a global public health problem. However, due to its complexity and heterogeneity, there ...
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Asthma management, focused on the use of oral corticosteroids: the opinions of Italian asthmatic patients J. Asthma (IF 1.9) Pub Date : 2024-04-05 Manuela Latorre, Angela Rizzi, Pierluigi Paggiaro, Ilaria Baiardini, Diego Bagnasco, Stefano DelGiacco, Carlo Lombardi, Vincenzo Patella, Eleonora Nucera, Roberta Parente, Giovanni Paoletti, Laura Pini, Erminia Ridolo, Gianenrico Senna, Francesco Blasi, Giorgio Walter Canonica, Arianna Aruanno, Carmen Ballacchino, Marco Bonavia, Cecilia Calabrese, Marco Caminati, Monica Carbonara, Cristina Cardini
Patients’ perceptions of asthma symptoms, and attitudes regarding diagnosis and management, can affect their ability to reach good asthma control. The aim of the study was to explore patients' perc...
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Functional Analysis of Airway Remodeling is Related with Fibrotic Mediators in Asthmatic Children J. Asthma (IF 1.9) Pub Date : 2024-04-05 Lucas P Salles-Dias, Maysa A R Brandao-Rangel, Amanda Cristina-Rosa, Rayssa T Morais-Felix, Simone Oliveira-Freitas, Luis V F Oliveira, Renilson Moraes-Ferreira, Andre L L Bachi, Elisa T Coutinho, Claudio R Frison, Asghar Abbasi, Dobroslav Melamed, Rodolfo P Vieira
Asthmatic children present variable degrees of airway inflammation, remodeling, and resistance, which correlate with disease control and severity. The chronic inflammatory process of the airway tri...
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Development and Psychometric Evaluation of the Asthma Action Plan Questionnaire (AAPQ) J. Asthma (IF 1.9) Pub Date : 2024-04-02 Yahya A. Alzahrani, Sharon Foley, Ellen A. Becker
Objective: The objective was to develop a practical and psychometrically sound tool to evaluate caregiver knowledge of their child’s asthma action plan (AAP).Methods: A pilot study was conducted in...
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The Frequency of Asthma and its Related Factors: Results of The Enrolment Phase of Tabari Cohort Study J. Asthma (IF 1.9) Pub Date : 2024-03-29 Seyed Sajjad Yousefi-Reykandeh, Mahmood Moosazadeh, Motahareh Kheradmand, Amirsaeed Hosseini, Masoumeh Bagheri-Nesami
IntroductionA large portion of the world's population has asthma. This study aimed to ascertain asthma prevalence and related factors in the Tabari cohort study (TCS).MethodsThe TCS included 10,255...
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Do early-life allergic sensitisation and respiratory infection interact to increase asthma risk? J. Asthma (IF 1.9) Pub Date : 2024-03-29 Vikas Wadhwa, Danielle Wurzel, Shyamali C Dharmage, Michael J Abramson, Caroline Lodge, Melissa Russell
Objective The ‘two-hit’ hypothesis theorizes that early life allergic sensitisation and respiratory infection interact to increase asthma risk.Methods We sought to determine in a high allergy risk ...
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Expert panel consensus recommendations on the utilization of nebulized budesonide for managing asthma and COPD in both stable and exacerbation stages in Thailand J. Asthma (IF 1.9) Pub Date : 2024-03-25 Phunsup Wongsurakiat, Akrawat Rattanawongpaibul, Atikun Limsukon, Chirawat Chiewchalermsri, Kittiyaporn Wiwatcharagoses, Kumpol Kornthatchapong, Narongkorn Saiphoklang, Pitsucha Sanguanwit, Pornanan Domthong, Theerasuk Kawamatawong, Tirachat Sewatanon, Wipa Reechaipichitkul, Kittipong Maneechotesuwan
This study investigated the utilization of nebulized budesonide for acute asthma and COPD exacerbations as well as for maintenance therapy in adults.We conducted a search on PubMed for nebulized bu...
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Effect of pulmonary rehabilitation on functional status dyspnea and quality of life among post COVID-19 patients J. Asthma (IF 1.9) Pub Date : 2024-03-25 Yatesh Sharma, Tanveer Alam, Ambreen Fatima, Sachin Gupta
To determine the Effect of pulmonary rehabilitation on functional status dyspnea and quality of life among post-COVID-19 patients.The study utilized an experimental study designwith a total of 120 ...
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The Impact of Insomnia and Depression on Asthma Control J. Asthma (IF 1.9) Pub Date : 2024-03-25 Sarah Rhoads, Jack Edinger, Aastha Khatiwada, Joy Zimmer, Pearlanne Zelarney, Michael E. Wechsler
Poor sleep quality is often reported by individuals with asthma, particularly by those who have poor asthma control overall. However, there is little understanding of how underlying sleep disorders...
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Medication Non-adherence and predictor factors among adult Asthmatic patients in Ethiopia: a Systematic review and Meta-Analysis J. Asthma (IF 1.9) Pub Date : 2024-03-25 Chernet Tafere, Bereket Bahiru, Adane Yehualaw, Desalegn Getnet Demsie, Kebede Feyisa, Malede Berihun Yismaw, Endalamaw Aschale, Zenaw Debasu, Zewdu Yilma, Zegaye Agmassie, Sileshi Mulatu, Yazachew Engida Yismaw, Ousman Adal, Destaw Endeshaw
Objective: A pronounced burden is evident in individuals with asthma, with approximately half of them not adhering to their prescribed medication. Therefore this study aimed to assess the pooled pr...
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Elevated Neutrophils and uncontrolled Asthma: the effects of caffeine, diet and co-morbidities J. Asthma (IF 1.9) Pub Date : 2024-03-25 Brendan Jen-Wei Tan, Bin Xiao, Eng-King Tan
Published in Journal of Asthma (Just accepted, 2024)
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Bronchiectasis Severity Index and FACED scores in patients with allergic bronchopulmonary aspergillosis complicating asthma: do they correlate with immunological severity or high-attenuation mucus? J. Asthma (IF 1.9) Pub Date : 2024-03-23 Shruti Phadnis, Valliappan Muthu, Inderpaul S Sehgal, Kuruswamy T Prasad, Sahajal Dhooria, Ashutosh N Aggarwal, Ritesh Agarwal
Background: The utility of two disease-severity indices, namely bronchiectasis severity index (BSI) and FACED score in allergic bronchopulmonary aspergillosis (ABPA) remains unknown.Objective: To c...
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Real-world clinical remission of severe asthma with benralizumab in Spanish adults with severe asthma J. Asthma (IF 1.9) Pub Date : 2024-03-23 Eva Martinez-Moragon, Eusebi Chiner, Alexandra Suliana Mogrovejo, Marta Palop Cervera, Inmaculada Lluch Tortajada, Ignacio Boira Enrique, Andrés Fernando Sánchez Vera
Patients with severe eosinophilic asthma experience high risk of exacerbations and reduced quality of life. Benralizumab, a monoclonal antibody binding to IL-5 receptor α subunit, is an approved dr...
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Analysis of the Potential Molecular Mechanisms of Asthma and Gastroesophageal Reflux Disease J. Asthma (IF 1.9) Pub Date : 2024-03-22 Changdan Chen, Wei Zhang, Xiujin Zheng, Chenglin Jiang, Wen Zhang
Asthma and gastroesophageal reflux disease (GERD) often occur simultaneously, with GERD being a comorbidity of asthma. This study aimed to explore the biological markers related to asthma and GERD ...
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Prevalence and Predictors of Medication Adherence among Adolescents and Adults with Asthma in Ethiopia: Systematic review and meta-analysis. J. Asthma (IF 1.9) Pub Date : 2024-03-21 Segenet Zewdie, Ewunetie Mekashaw Bayked, Wondim Ayenew, Abyou Seyfu, Assefa Andargie
This review aimed to estimate the pooled prevalence and predictors of medication adherence among adolescents and adults with asthma in Ethiopia.Primary studies were searched from PubMed, Scopus, HI...
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Prevalence of Asthma Triggers and Control Status Among Pediatric Asthmatic Patients in Saudi Arabia J. Asthma (IF 1.9) Pub Date : 2024-03-20 Mohammed M. Alyami, Ahmed H Alasimi, Abdullah A. Alqarni, Fahad H. Balharith, Abdulelah M. Aldhahir
Aim: This study aims to assess the prevalence of asthma triggers and control status among pediatric asthmatic patients in Saudi Arabia.Methods: From October 2015 to March 2016, an Arabic version of...
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The Association of Infant and Mother Gut Microbiomes with Development of Allergic Diseases in Children: A Systematic Review J. Asthma (IF 1.9) Pub Date : 2024-03-20 Amir-Hossein Mousavian, Fateme ZareGarizi, Behnaz Ghoreshi, Siavash Ketabi, Solat Eslami, Hanieh-Sadat Ejtahed, Mostafa Qorbani
ObjectiveIt is believed that gut microbiota alteration leads to both intestinal and non-intestinal diseases in children. Since infants inherit maternal microbiota during pregnancy and lactation, re...
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Efficacy and Safety of Once-Daily Vilanterol/Fluticasone Furoate MDI in Persistent Asthma: Phase 3 OD-INHALE study J. Asthma (IF 1.9) Pub Date : 2024-03-15 Avdhesh Kumar, Manish Kumar Jain, Vijaykumar Bhagwan Barge, Raghumanda Sunil Kumar, Neeraj Gupta, Harendra Yadav, Amitava Pal, Vivek Eknath Redkar, Asish Mondal, Rahul Kumar Rathore, Pavankumar Daultani, Ashok Jaiswal, Ravi T. Mehta
Introduction: Once-daily inhalers have been shown to improve adherence leading to lesser discontinuation compared to twice- or thrice-daily inhalers in management of asthma. Combination of Vilanter...
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Bacterial antigens and asthma: a comparative study of common respiratory pathogenic bacteria J. Asthma (IF 1.9) Pub Date : 2024-03-13 Jie Pang, Yifan Shi, Dan Peng, Lele Cui, Yingjie Xu, Wenjing Wang, Yue Hu, Yiran Yang, Jingjing Wang, Xiaofeng Qin, Yue Zhang, Hao Meng, Dan Wang, Ge Bai, Huihui Yuan, Jie Liu, Zhe Lv, Yan Li, Ye Cui, Wenjun Wang, Kewu Huang, Chris J Corrigan, Wei Wang, Yan Chen, Sun Ying
In a previous study we have shown that, in the presence of interleukin (IL)-33, repeated, per-nasal challenge of murine airways with Streptococcus pneumoniae (S. pneumoniae) organisms induces human...
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Cost-effectiveness of mepolizumab for severe eosinophilic asthma in China J. Asthma (IF 1.9) Pub Date : 2024-03-12 Xiong Chaogang, An Mengna, Wang Zhen, Li Ying, Gu Xin, Zhang Xin, Zhang Shengjie, Zhao Yuan, Lei Qian, Ma Wenbin, Feng Weiyi
To evaluate the economic value of mepolizumab as an add-on therapy to the standard of care (SoC) for patients with severe eosinophilic asthma in China.A Markov model with three health conditions wa...
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ARE NIGHT-TIME RESPIRATORY SYMPTOMS ASSESSED BY ASTHMA CONTROL TEST AFFECTED BY COMORBIDITIES? J. Asthma (IF 1.9) Pub Date : 2024-03-06 Alida Benfante, Alessandra Tomasello, Chiara Caponetto, Salvatore Battaglia, Nicola Scichilone
Nocturnal symptoms are common in the asthmatic population, reflecting an exaggerated airway narrowing overnight due to several factors; it is questioned to what extent the awakenings documented in ...
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Cost-Utility Analysis of Prenatal Supplementation with Long-Chain n-3 Fatty Acids to Reduce the Incidence of Wheezing and Asthma in Neonates. J. Asthma (IF 1.9) Pub Date : 2024-03-01 jefferson Antonio buendia, Diana Guerrero-Patino, Andres Zuluaga
Published in Journal of Asthma (Just accepted, 2024)
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Reactance inversion in moderate to severe persistent asthma: low birth weight, prematurity effect, and bronchodilator response J. Asthma (IF 1.9) Pub Date : 2024-03-01 Ramiro González Vera Dr., Alberto Vidal Grell Dr., José A Castro-Rodríguez Dr., María A Palomino Montenegro Dra., Alejandra Méndez Yarur
Introduction Reactance Inversion (RI) has been associated with impaired peripheral airway function in persistent asthma. However, there is little to no data about the difference between asthmatic c...
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Screening Asthmatics for Atopic Status using the ALergy EXplorer (ALEX2) Macroarray J. Asthma (IF 1.9) Pub Date : 2024-02-28 Robert G Hamilton, Mark Holbreich, Charles Bronzert, Rebecca L Anderson, Nathan Schoettler, Carole Ober
Background: Screening asthma patients for atopy facilitates management. Since 2010, the core biomarker for screening asthma subjects for atopic status has been the qualitative Phadiatop. multi-aero...
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A Comprehensive Review of the Intersection Between Asthma and Depression J. Asthma (IF 1.9) Pub Date : 2024-02-28 Tahoora Abdul Nasir Surve, DhruviKumari D Sharma, Kiyan Ghani Khan, Neisha Ghanie, Riley Charanrak, Mouhammad Sharifa, Samreen Begum, Maria Jose Auz, Nozima Akbarova, Maneeth Mylavarapu
Objective To emphasize the necessity for increased research in this field, incorporating depression into the preventative, diagnostic, and therapeutic considerations for asthma. Additionally, we se...
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Identification of Two Hub Genes and miRNA‑mRNA Interactions in Chronic Obstructive Pulmonary Disease (COPD) Plasma J. Asthma (IF 1.9) Pub Date : 2024-02-27 Yuanyuan Qian, Yifei Li, Jiancheng Ji, Zhaojunli Wang
We aimed to identify hub genes in chronic obstructive pulmonary disease (COPD) plasma through the exploration of a putative miRNA–mRNA regulatory network.Three datasets (GSE24709, GSE102915, GSE136...
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Prevalence of aeroallergen sensitization in children in Northern China J. Asthma (IF 1.9) Pub Date : 2024-02-26 Sainan Bian, Wenjing Zhu, Kai Guan, Li Sha
This study aimed to analyze the sensitization rate of different aeroallergens in children of different age, sex, and disease groups, describe the changing trend of different aeroallergens in differ...
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N-Acetyl Cysteine Augments Adipose Tissue-Derived Stem Cell Efficacy on Inflammatory Markers and Regulatory T Cell System Balance in an Allergic Asthma Model J. Asthma (IF 1.9) Pub Date : 2024-02-20 Maryam Radan, Farhad Abol Nejadian, Vahid Bayati, Ali Asghar Hemmati, Khojasteh Hoseinynejad, Seyyed Ali Mard
Background Allergic asthma is a destructive inflammatory process in the respiratory system. The anti-inflammatory and antioxidant effects of N-acetylcysteine (NAC) have been reported in patients wi...
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Clinical characteristics of children with asthma exacerbations: A cross-sectional descriptive study J. Asthma (IF 1.9) Pub Date : 2024-02-20 Ezgi Cay, Veysel Karakulak, Ahmet Sezer, Huseyin Baspinar, Nilgun Bahar, Busra Hatice Fidan, Mahir Serbes, Sevcan Bilen, Sevinc Puren Yucel, Dilek Ozcan, Derya Ufuk Altintas
Aim: In this cross-sectional descriptive study, we aimed to determine the clinical characteristics of children admitted to a tertiary hospital with asthma exacerbations in a city in southern Turkey...
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Impact of the pulmonary ventilation function on the prognosis of suspected asthma patients: A retrospective observational study J. Asthma (IF 1.9) Pub Date : 2024-02-22 Ming-juan Zhou, Li Fu, Wen-qian Lin, Zhen-ni Wu, Fang Nie, Chu-yin Ye, Wen-han Zhao
Asthma is a common chronic respiratory diseases, and the relationship between pulmonary ventilation function and the prognosis of patients with suspected asthma is not well understood. This study a...
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Relationship between serum IgA levels and low percentage forced expiratory volume in the first second in asthma J. Asthma (IF 1.9) Pub Date : 2024-02-20 Sahoko Imoto, Maho Suzukawa, Kazufumi Takada, Shizuka Watanabe, Asari Isao, Takahide Nagase, Hiroyuki Nagase, Ken Ohta
Immunoglobulin A (IgA) is suggested to have pathogenic effects in respiratory inflammatory diseases, including asthma. We aimed to analyze the relationship between serum IgA, and clinical indicator...
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Evaluation of the quality and content of YouTube videos as an educational resource in developing patients' inhaler use skills J. Asthma (IF 1.9) Pub Date : 2024-02-15 Ozlem Canbolat, Ayse Buket DoganAktas, Gulhayat Sipal, Kokturk Nurdan
Background: YouTube has educational videos on inhalers. However, their content and quality are not adequately known.Objectives: This study investigated the quality and content of educational YouTub...
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The Turkish Adaptation of The Adherence to Asthma Medication Questionnaire J. Asthma (IF 1.9) Pub Date : 2024-02-15 Döndü Erdoğan İnan, Ülkü Polat
Background: This study was conducted to adapt the Adherence to Asthma Medication Questionnaire (AAMQ-13) into Turkish.Methods: The research was conducted in the pulmonology outpatient clinic of a s...
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Toll-like receptor 4 Mediated Autophagy regulates Airway Smooth Muscle Cells behavior J. Asthma (IF 1.9) Pub Date : 2024-02-13 LiXia Hou, HuiQing Zuo, Bo Xiao, Dong Yao
Objectives: Airway remodeling, a prominent feature of asthma, involves aberrant proliferation, apoptosis, and migration of airway smooth muscle cells (ASMCs). Toll-like receptors (TLRs) are implica...
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The relationships between Physical activity and asthma control and Body Mass Index (BMI) in patients with asthma J. Asthma (IF 1.9) Pub Date : 2024-02-08 Bonny Rockette-Wagner, Juan P. Wisnivesky, Fernando Holguin, Jyoti Ankam, Arushi Arora, Emily Federmann, Vongphone Smith, Alex D. Federman, Molly B. Conroy
Asthma is one of the most common chronic conditions in developed countries. We examined whether physical activity (PA) is related to asthma control and body mass index (BMI) in asthma patients.Cros...
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Machine learning-based prediction of in-hospital mortality in patients with pneumonic chronic obstructive pulmonary disease exacerbations J. Asthma (IF 1.9) Pub Date : 2024-02-08 Lin Yu, Xia Ruan, Wenbo Huang, Na Huang, Jun Zeng, Jie He, Rong He, Kai Yang
While linear regression and LASSO models have been established for predicting in-hospital mortality, there is currently no validated clinical prediction algorithm to predict in-hospital mortality f...
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Tropical high altitude and severe asthma in adults: house dust mite sensitization and phenotypic distribution J. Asthma (IF 1.9) Pub Date : 2024-02-08 Carlos A. Torres-Duque, Abraham Alí-Munive, Diego Severiche-Bueno, Mauricio Durán-Silva, Carlos E. Aguirre-Franco, Angélica González-Florez, María José Pareja-Zabala, Libardo Jiménez-Maldonado, Mauricio Gonzalez-Garcia
There is a lack of information on house dust mite (HDM) sensitization and phenotype distribution in patients with severe asthma (SA) living permanently at high-altitude (HA) in tropical regions, wh...
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Safety and efficacy of benralizumab in elderly subjects with severe asthma J. Asthma (IF 1.9) Pub Date : 2024-02-08 Marcela Valverde-Monge, Remedios Cárdenas, Ismael García-Moguel, Ana Rosado, Mar Gandolfo-Cano, Teresa Robledo Echarren, María del Mar Moro-Moro, María del Mar Reaño Martos, Rafael Pineda-Pineda, Cristina Martin-Arriscado Arroba, Javier Domínguez-Ortega, AIRE Group
The prevalence of asthma in adults >65 years old is approximately 12–14%, and 10% have severe asthma. A higher mortality rate is observed in subjects with asthma >65 years old and especially >80 ye...
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Adherence to the asthma pathway, including pre-triage bronchodilator history, reduces hospitalizations J. Asthma (IF 1.9) Pub Date : 2024-02-08 Suttipong Ittiporn, Kanlaya Prajongdee
Objective: To determine if adherence to an asthma treatment pathway is associated with a decrease in hospitalizations.Methods: A prospective cohort design was conducted of Thai children aged 2–15 y...
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Efficacy of Bhramari pranayama and Om chanting on asthma control, quality of life, and airway inflammation in asthmatic children: an open-label randomized controlled trial J. Asthma (IF 1.9) Pub Date : 2024-02-08 Rashmi Yadav, Sushil Kumar Kabra, Raj Kumar Yadav, Arnab Nandy, Ashish Datt Upadhyay, Kana Ram Jat, Rakesh Lodha
To explore the efficacy of combination of Bhramari pranayama and om chanting as an adjunct to standard pharmacological treatment on asthma control, quality of life, pulmonary function, and airway i...
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Activation of Notch1-GATA3 pathway in asthma bronchial epithelial cells induced by acute PM2.5 exposure and the potential protective role of microRNA-139-5p J. Asthma (IF 1.9) Pub Date : 2024-02-12 Junjun Huang, Yan Hu, Yunxia Wang, Zhou Jin
PM2.5 is closed linked to asthma exacerbation. The Notch1 pathway acts as an important pathway, ultimately inducing T-helper cells that express GATA3 and its corresponding Th2 cytokines. The regula...
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Emergency Management and Asthma Risk in Young Medicaid-Enrolled Children with Recurrent Wheeze J. Asthma (IF 1.9) Pub Date : 2024-02-07 Isabel J. Hardee, Isabella Zaniletti, Melisa S. Tanverdi, Andrew H. Liu, Rakesh D. Mistry, Nidhya Navanandan
To describe clinical characteristics of young children presenting to the emergency department (ED) for early recurrent wheeze, and determine factors associated with subsequent persistent wheeze and...
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Digitally monitored inhaled therapy: A ‘Smart’ way to manage severe asthma? J. Asthma (IF 1.9) Pub Date : 2024-02-07 Dominic L Sykes, Yee Yong See, Evon C Y Chow, Michael G Crooks, Helena Cummings, Mandy Robinson, Karen Watkins, Joanne Thompson, Kylie Overton, Charlotte Riches, Shoaib Faruqi
One of the fundamental challenges of managing patients with severe asthma is treatment adherence, particularly with inhaled corticosteroids. Adherence is difficult to measure objectively and poor a...
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Effect of stearoyl-coenzyme a desaturase 1 (SCD1) on the function of mast cells J. Asthma (IF 1.9) Pub Date : 2024-02-05 Xiuqing Zhang, Aiguo Li, Yifan Zhu, Feng Liu, Deyu Zhao, Heng Tang, Changdi Xu
Background: The prevalence of childhood asthma and obesity is increasing, while obesity increases the risk and severity of asthma. Lipid metabolism has been considered as an important factor in the...
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Evaluating the implementation of a community health worker-delivered intervention integrating asthma care in West Philadelphia public schools J. Asthma (IF 1.9) Pub Date : 2024-02-01 Kayla Clark, Elizabeth Messineo, Tyra Bryant-Stephens, Angela Song, Darby Marx, Adina Lieberman, Rinad S. Beidas, Courtney Benjamin Wolk
Schools are an important setting because students spend much of their time in school and engage in physical activity during the school day that could exacerbate asthma symptoms. Our objective is to...
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Near fatal asthma in a case of allergic bronchopulmonary aspergillosis (ABPA) treated with ECMO J. Asthma (IF 1.9) Pub Date : 2024-01-31 Shili Zhong, Zhengbin Wu, Chunyan Chen, Hong Xiao, Zhen Wang
Fatal asthma is a rapidly progressing and highly fatal form of asthma. Mechanical ventilation, although necessary for respiratory support, can exacerbate the condition and lead to ventilator-associ...
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Rapidly progressive mucus plugs in allergic bronchopulmonary mycosis J. Asthma (IF 1.9) Pub Date : 2024-01-31 Osamu Miyazaki,, Akira Igarashi,, Kento Sato,, Sumito Inoue,, Ryuto Yokoyama,, Masaki Nakane,, Sahoko Kodama,, Ryo Hasegawa,, Shigeharu Ueki,, Takashi Yaguchi,, Akira Watanabe,, Masafumi Watanabe
Allergic bronchopulmonary mycosis (ABPM) is a chronic airway disease characterized by the presence of fungi that trigger allergic reactions and airway obstruction. Here, we present a unique case of...
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Atomized inhalation of Icaritin reduces airway inflammation and remodeling in asthmatic mice J. Asthma (IF 1.9) Pub Date : 2024-01-31 Yintong He, Jian Cui, Bo Xiao, Lixia Hou, Zhimei Li, Huiqin Zuo, Yutong He, Dong Yao
Asthma is a disease characterized by airway hyperresponsiveness and airway inflammation. Icaritin (ICT) is a plant hormone with various pharmacological activities such as anti-inflammatory, immune ...
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Insight into the role of mitochondrion-related gene anchor signature in mitochondrial dysfunction of neutrophilic asthma J. Asthma (IF 1.9) Pub Date : 2024-01-31 Lu Lin, Zeng-hua Liao, Chao-qian Li
At present, targeting molecular-pharmacological therapy is still difficult in neutrophilic asthma. The investigation aims to identify and validate mitochondrion-related gene signatures for diagnosi...
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Efficacy of bronchial thermoplasty in a patient panel with uncontrolled severe persistent asthma J. Asthma (IF 1.9) Pub Date : 2024-01-31 Antonios Zikos, Marvin Balaan, Emily Hobart, Sandeep Bansal, Rihab Saeed, Tariq Cheema, Deborah Gentile
Bronchial thermoplasty (BT) is an approved procedure to manage uncontrolled severe persistent asthma. Many insurance providers are reluctant to pay for BT without proven benefit among their specifi...
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Biologics for asthma and risk of pneumonia J. Asthma (IF 1.9) Pub Date : 2024-01-31 Maria Gabriella Matera, Josuel Ora, Luigino Calzetta, Paola Rogliani, Mario Cazzola
Modification of the immune system with biologics raises theoretical concerns about the risk of infections but it is still unclear whether currently routinely used biologics in severe asthma may fac...
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There is no association between serum endotoxin levels and inflammation in asthma J. Asthma (IF 1.9) Pub Date : 2024-01-30 Ozlem Candan, Tayfur Toptas, Semra Demir, Fusun Erdenen
Endotoxin, in lipopolysaccharide structure (LPS), is the main component of the outer membrane of gram negative bacteria. LPS levels were associated with inflammatory disease. Asthma is a chronic in...
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Assessment of acute asthma in children: Do parents and healthcare providers speak the same language? J. Asthma (IF 1.9) Pub Date : 2024-01-24 J.V. Markwat, J. vanLeeuwen, A. W. A. Kamps
ObjectiveEducation and self-management plans enhance parents' self-efficacy in managing their child's asthma symptoms. By understanding how parents recognize and interpret acute asthma symptoms, we...
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Decoding the Genetic Landscape of Allergic Rhinitis: A Comprehensive Network Analysis Revealing Key Genes and Potential Therapeutic Targets J. Asthma (IF 1.9) Pub Date : 2024-01-24 Chile Yuan, Xiaohong Lin, Ruosha Liao
Allergic Rhinitis (AR), an inflammatory affliction impacting the upper respiratory tract, has been registering a substantial surge in incidence across the globe.We embarked on examination of differ...
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Anti-IL-5 and anti-IL-5R biologics for severe asthma. Are there any differences in their effects? J. Asthma (IF 1.9) Pub Date : 2024-01-24 P Granda, E Villamañán, C Carpio, D Laorden, S Quirce, R Álvarez-Sala, on behalf of the NEUMO Study Group
The aim of this retrospective multicentre study is to describe the clinical characteristics of patients diagnosed with severe eosinophilic asthma receiving anti-IL-5/anti-IL-5Rα therapies and to co...