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Prediction of cardiovascular and renal risk among patients with apparent treatment‐resistant hypertension in the United States using machine learning methods J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-25 George Bakris, Pei (Paul) Lin, Chang Xu, Cindy Chen, Veronica Ashton, Mukul Singhal
Apparent treatment‐resistant hypertension (aTRH), defined as blood pressure (BP) that remains uncontrolled despite unconfirmed concurrent treatment with three antihypertensives, is associated with an increased risk of developing cardiovascular and renal complications compared with controlled hypertension. We aimed to identify the characteristics of aTRH patients with an elevated risk of major adverse
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Does home blood pressure monitoring improve blood pressure‐related outcomes in people living with chronic kidney disease? A systematic review J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-25 Nathan P. Carey, Ffion Curtis, McKenna L. Eisenbeisz, Sadaf Akbari, Meenakshi Sambharia, Diana I. Jalal, Thomas J. Wilkinson
High blood pressure is an important risk factor for cardiovascular disease and disease progression in chronic kidney disease (CKD). Evidence on the effects of home blood pressure monitoring (HBPM) is limited. This review aimed to determine the effect of HBPM on systolic (SBP) and diastolic blood pressure (DBP) in patients with CKD. We searched medical literature databases for eligible studies presenting
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Blood pressure difference between pre and post‐menopausal women and age‐matched men: A cross‐sectional study at a tertiary center J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-25 Hussein Alhawari, Osama Alzoubi, Sameeha Alshelleh, Leen Alfaris, Mohamad Abdulelah, Saif Aldeen AlRyalat, Saleh Altarawneh, Mohammad Alzoubi
Hypertension is a prominent risk factor for cardiovascular and cerebrovascular diseases. Gender differences and menopausal status contribute to blood pressure changes across the lifespan which have not been completely characterized. Our study aims to explore the impact of multiple factors on blood pressure levels in previously healthy women and men. Factors of interest included gender, menopausal status
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Analysis of changes in high‐mobility group box 1, receptor for advanced glycation endproducts, and T helper 17/regulatory T balance in severe preeclampsia with acute heart failure J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-25 Chen De, Liang Xuan, Zhang jingjing, Zhang Honghong, Zuo Kun, Du Song, Song Yaqi, Jiang Ying, Cheng Cheng, Liu Jian
We measured the levels of High‐Mobility Group Box 1 (HMGB1), Receptor for Advanced Glycation Endproducts (RAGE), T Helper 17 cells (Th17), Regulatory T cells (Treg), and related cytokines in the peripheral blood of patients with severe preeclampsia (SPE) complicated with acute heart failure (AHF) to explore the expression changes in these indicators. In total, 96 patients with SPE admitted to Gansu
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Association of postexercise blood pressure with cardiovascular outcomes and mortality: The CARDIA study J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-19 Jia‐Jie Wang, Zhichao Zheng, Ying Zhang
Postexercise blood pressure (BP) may be a better predictor of cardiovascular risk than office BP, but there is a lack of data supporting this claim. We hypothesized that postexercise BP may be an important prognostic marker. Our aim was to evaluate the association of postexercise BP with major adverse cardiovascular events (MACE) and all‐cause mortality. A total of 2581 participants (median age, 46
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Origins of a novel mobile health unit program to prevent cardiovascular disease in vulnerable communities J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-19 Michael J. Twiner, Nora N. Akcasu, Bethany Foster, Ijeoma Nnodim Opara, Samantha J. Bauer, Steven J. Korzeniewski, Robert D. Brook, Phillip D. Levy
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Comparative safety and effectiveness of angiotensin converting enzyme inhibitors and thiazides and thiazide‐like diuretics under strict monotherapy J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-19 Tara V. Anand, Fan Bu, Martijn J. Schuemie, Marc A. Suchard, George Hripcsak
Previous work comparing safety and effectiveness outcomes for new initiators of angiotensin converting‐enzyme inhibitors (ACEi) and thiazides demonstrated more favorable outcomes for thiazides, although cohort definitions allowed for addition of a second antihypertensive medication after a week of monotherapy. Here, we modify the monotherapy definition, imposing exit from cohorts upon addition of another
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Joint association and interaction of birth weight and lifestyle with hypertension: A cohort study in UK Biobank J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-16 Ziyi Zhang, Xiaowen Liu, Ninghao Huang, Ming Jin, Zhenhuang Zhuang, Zeping Yang, Xiaojing Liu, Tao Huang, Nan Li
Low birth weight and unhealthy lifestyle are both associated with an increased risk of hypertension. The authors aimed to assess the joint association and interaction of birth weight and lifestyle with incident hypertension. The authors included 205 522 participants free of hypertension at baseline from UK Biobank. A healthy lifestyle score was constructed using information on body mass index, physical
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Adherence to antihypertensives in the United States: A comparative meta‐analysis of 23 million patients J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-16 Yomna E. Dean, Karam R. Motawea, Mohamed A. Shebl, Sameh Samir Elawady, Kaamel Nuhu, Basel Abuzuaiter, Karen Awayda, Ahmed Mahmoud Fouad, Yousef Tanas, Raquel Batista, Ahmed Elsayed, Noheir A. I. F Hassan, Amro A. El‐Sakka, Walaa Hasan, Raabia Husain, Amanda Lois, Aryan Arora, Abhinav Arora, Elyas Ayad, Mohamed A. Elbahaie, Jaffer Shah, Amr Shady, Debanik Chaudhuri, Hani Aiash
Adherence to antihypertensives is crucial for control of blood pressure. This study analyzed factors and interventions that could affect adherence to antihypertensives in the US. PubMed, Scopus, Web of Science, and Embase were searched on January 21, 2022 and December 25, 2023 for studies on the adherence to antihypertensives in the US. Nineteen studies and 23 545 747 patients were included in the
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The causal role of circulating immunity‐inflammation in preeclampsia: A Mendelian randomization J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-13 Xiaolei Xue, Chuanhui Guo, Cuifang Fan, Di Lei
Patients with systemic autoimmune diseases, such as systemic lupus erythematosus, were at a higher risk for preeclampsia. The causal relationship between immunological inflammation and preeclampsia (PE) remains uncertain. We aimed to investigate the causal relationship between circulating immune inflammation and PE. Genetically predicted blood immune cells and circulating inflammatory proteins were
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Cognitive behavior therapy for insomnia for untreated hypertension with comorbid insomnia disorder: The SLEEPRIGHT clinical trial J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-12 Andrew Sherwood, Christi Ulmer, Jade Q. Wu, James A. Blumenthal, Emma Herold, Patrick J. Smith, Gary G. Koch, Kristy Johnson, Anthony Viera, Jack Edinger, Alan Hinderliter
Insomnia and poor sleep are associated with an increased risk of developing cardiovascular disease (CVD) and its precursors, including hypertension. In 2022, the American Heart Association (AHA) added inadequate sleep to its list of health behaviors that increase the risk for CVD. It remains unknown, however, whether the successful treatment of insomnia and inadequate sleep can reduce heightened CVD
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Effectiveness of the knowledge, attitude, practice intervention model in the management of hypertension in the elderly J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-12 Li‐Shuang Xu, Zhi‐Guang Gao, Mei He, Ming‐Da Yang
This study illustrated the effectiveness of the knowledge, attitude, practice (KAP) intervention model for community hypertension in the elderly by the community physician‐led, describing the study design and baseline data. The aim of the study was to compare the changes in the elderly hypertensive population before and after the KAP intervention model by managing the elderly hypertensive patients
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Clinical diagnosis of pheochromocytoma and paraganglioma-induced secondary hypertension through UPLC-MS/MS analysis of plasma catecholamines and their metabolites J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-08 Weiyun Zhang, Xiao Li, Wanqin Li, Yanmei Zhang, Jiajia Cai, Shiyu Feng, Zhaohui Sun
This study aimed to elucidate the clinical diagnostic value of plasma catecholamines and their metabolites for pheochromocytoma and paraganglioma (PPGL)-induced secondary hypertension using ultraperformance liquid chromatography-mass spectrometry (UPLC-MS/MS). The study population included 155 patients with PPGL that were divided into the PPGL with hypertension (n = 79) and a PPGL without hypertension
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Omega‐3 fatty acids and their influence on hypertension and coronary atherosclerosis: Insights from a Mendelian randomization approach J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-07 Yuchen Song, Qun Wang, Lianqun Jia
It has been suggested that Omega‐3 fatty acids may improve endothelial thickness and thereby reduce the onset of cardiovascular diseases such as coronary atherosclerosis and hypertension. However, published observational epidemiological studies on the relationship between cardiovascular disease (CVD) and Omega‐3 fatty acids remain inconclusive. Here, we performed a two‐sample Mendelian randomisation
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Association between nocturnal blood pressure phenotype and adverse cardiovascular prognosis in patients with coronary heart disease and hypertension J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-07 Yao Du, Binbin Zhu, Yahui Liu, Weicen Zhou, Zhou Du, Wei Yang, Chuanyu Gao
Nocturnal blood pressure and nighttime dipping patterns are associated with the occurrence of cardiovascular events. However, there is few research on whether riser pattern is associated with the poor prognosis of patients with coronary heart disease (CHD) and hypertension independent of nighttime systolic blood pressure (SBP). This prospective and observational clinical study included 568 hospitalized
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Ambulatory blood pressure levels in individuals with uncontrolled clinic hypertension across Bangladesh, Pakistan, and Sri Lanka J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-07 Anqi Zhu, Truls Ostbye, Aliya Naheed, H Asita de Silva, Imtiaz Jehan, Mihir Gandhi, Nantu Chakma, Anuradhani Kasturiratne, Zainab Samad, Tazeen Hasan Jafar
Hypertension is a leading risk factor for cardiovascular disease in South Asia. The authors aimed to assess the cross‐country differences in 24‐h ambulatory, daytime, and nighttime systolic blood pressure (SBP) among rural population with uncontrolled clinic hypertension in Bangladesh, Pakistan, and Sri Lanka. The authors studied patients with uncontrolled clinic hypertension (clinic BP ≥ 140/90 mmHg)
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Comparing urine point‐of‐care tests to screen preeclampsia: Congo‐red dot paper test versus dipstick urinalysis J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-02 Liying Wang, Jinsong Gao, Pingping Tang, Huiying Hu, Xiaoxu Chen, Ziyi Chen, Yin Sun
To compare the urine Congo‐red dot paper test (CRD) with dipstick urinalysis to screen preeclampsia (PE). A total of 409 paired spot urine samples were obtained prospectively from women with suspected pre‐eclampsia attending for routine hospital visits. Congo‐red dot paper test and dipstick urinalysis were examined and compared to screen pre‐eclampsia. The agreement between the two urinary test is
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Association between metformin treatment and coronary artery inflammation based on pericoronary adipose tissue attenuation in type 2 diabetes mellitus patients J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-02 Yuankang Liu, Yue Dong, Xiang Wang, Xiangyang Xu
Cardiovascular disease (CVD) is the leading cause of mortality in type 2 diabetes mellitus (T2DM) patients. The role of metformin in reducing cardiovascular events is well‐established, but its effect on coronary artery inflammation in T2DM patients is still unclear. In this study, we evaluated 547 T2DM patients who underwent coronary computed tomography angiography (CCTA) at Wuhan Central Hospital
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Nomogram‐based risk assessment model for left ventricular hypertrophy in patients with essential hypertension: Incorporating clinical characteristics and biomarkers J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-02 Chuang‐chang Wang, Li‐Keng Liang, Sheng‐ming Luo, Hui‐Cheng Wang, Xiao‐li Wang, Ya‐Hui Cheng, Guang‐ming Pan, Jiang‐Yang Peng, Shu‐jie Han, Xia Wang
Left ventricular hypertrophy (LVH) is a hypertensive heart disease that significantly escalates the risk of clinical cardiovascular events. Its etiology potentially incorporates various clinical attributes such as gender, age, and renal function. From mechanistic perspective, the remodeling process of LVH can trigger increment in certain biomarkers, notably sST2 and NT‐proBNP. This multicenter, retrospective
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Efficacy and safety of 3D reconstruction and basket multi‐electrode renal denervation (RDN) for refractory hypertensive patients with chronic kidney disease J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-02 Han Cai, Zhoufei Fang, Xiangshu Wu, Wei Zhou, Jinxiu Lin, Feng Peng, Jinzi Su
Renal Artery Sympathetic Denervation (RDN) can lower blood pressure. Different ablation catheters (single electrode, multi‐electrode) have different scopes of ablation (renal artery main stem and branches). Few studies have compared the advantages and disadvantages of different ablation catheters and different procedures in terms of antihypertensive efficacy. To compare the efficacy and safety of 3D
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Urinary protein and coagulation‐fibrinolysis indicators in preeclampsia: Expression and significance J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-02 Zhen Chen, Fang Fang, Xiaoqian Yu
This study investigates the expression and significance of urinary protein and coagulation‐fibrinolysis indicators in preeclampsia, categorized into mild preeclampsia (109 cases) and severe preeclampsia (97 cases) based on disease severity. Additionally, 110 patients with gestational hypertension (gestational hypertension group) were included for comparative analysis. General information, laboratory
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ATP2B1 gene polymorphisms associated with resistant hypertension in the Japanese population J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-03-02 Yusuke Kobayashi, Keisuke Yatsu, Aiko Haruna, Rina Kawano, Moe Ozawa, Tatsuya Haze, Shiro Komiya, Shota Suzuki, Yuki Ohki, Akira Fujiwara, Sanae Saka, Nobuhito Hirawa, Yoshiyuki Toya, Kouichi Tamura
Single‐nucleotide polymorphisms (SNP) of ATP2B1 gene are associated with essential hypertension but their association with resistant hypertension (RHT) remains unexplored. The authors examined the relationship between ATP2B1 SNPs and RHT by genotyping 12 SNPs in ATP2B1 gene of 1124 Japanese individuals with lifestyle‐related diseases. Patients with RHT had inadequate blood pressure (BP) control using
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Association of plasma homocysteine with peripheral arterial disease in the hypertensive adults: A cross‐sectional study J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-20 Chuanli Yu, Congcong Ding, Lihua Hu, Yumeng Shi, Peixu Zhao, Jin´e Liu, Liting Zhang, Dan Sun, Wei Zhou, Chao Yu, Tao Wang, Lingjuan Zhu, Xiao Huang, Huihui Bao, Xiaoshu Cheng
Increased plasma homocysteine (Hcy) has been identified as one of the important risk factors for cardiovascular disease. However, the association between plasma Hcy and peripheral artery disease (PAD) is still controversial. This study aimed to investigate the association between plasma Hcy and PAD and the potential modifier factors in Chinese hypertensive adults. A total of 25 300 hypertensive patients
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Nocturnal blood pressure dipping, blood pressure variability, and cognitive function in early and middle-aged adults J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-08 Katerina Massengale, Vernon A. Barnes, Celestin Williams, Asifhusen Mansuri, Kimberly Norland, Michelle Altvater, Hallie Bailey, Ryan A. Harris, Shaoyong Su, Xiaoling Wang
Higher nighttime blood pressure (BP), less BP dipping, and higher BP variability have been linked with worse cognitive function in the elderly. The goal of this study is to explore whether this relationship already exists in early and middle adulthood. We further examined whether ethnic differences between African Americans and European Americans in BP parameters can explain ethnic differences in cognitive
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A predictive model for postoperative adverse outcomes following surgical treatment of acute type A aortic dissection based on machine learning J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-11 Lin-feng Xie, Yu-ling Xie, Qing-song Wu, Jian He, Xin-fan Lin, Zhi-huang Qiu, Liang-wan Chen
Acute type A aortic dissection (AAAD) has a high probability of postoperative adverse outcomes (PAO) after emergency surgery, so exploring the risk factors for PAO during hospitalization is key to reducing postoperative mortality and improving prognosis. An artificial intelligence approach was used to build a predictive model of PAO by clinical data-driven machine learning to predict the incidence
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Reversal of cardiac and renal damage in a teenager with hypertension: A case report J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-06 Huiyu Du, Shilei Gao, Wenyong Dong, Qi Huang, Huiyun Qu, Chen Zhang, Linya Guo, Zhilan Liu, Min Liu
The authors describe the case of a 16-year-old male who was incidentally found to have a blood pressure of 200/? mmHg 6 months previously due to blurred vision and was diagnosed with “high risk of hypertension grade 3, renal insufficiency, hypertensive encephalopathy, hypertensive heart disease, and fundus hemorrhage” after relevant examinations were performed. His blood pressure fluctuated around
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Efficacy and safety of combination therapy with telmisartan, rosuvastatin, and ezetimibe in patients with dyslipidemia and hypertension: A randomized, double-blind, multicenter, therapeutic confirmatory, phase III clinical trial J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-06 Chan Joo Lee, Woong Chol Kang, Sang Hyun Ihm, Il Suk Sohn, Jong Shin Woo, Jin Won Kim, Soon Jun Hong, Jung Hyun Choi, Jung-Won Suh, Jae-Bin Seo, Joon-Hyung Doh, Jung-Woo Son, Jae-Hyeong Park, Ju-Hee Lee, Young Joon Hong, Jung Ho Heo, Jinho Shin, Seok-Min Kang
This study aimed to compare and evaluate the efficacy of the blood pressure (BP) control and cholesterol-lowering effects and safety of combination therapy with telmisartan, rosuvastatin, and ezetimibe versus rosuvastatin and ezetimibe double therapy or telmisartan single therapy in dyslipidemia patients with hypertension. After a wash-out/therapeutic lifestyle change period of ≥4 weeks, a total of
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Association between HDL-C and intensive blood pressure control in patients with hypertension: A post-hoc analysis of SPRINT J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-06 Rufei Liu, Wenli Cheng
Previous studies in patients with hypertension have demonstrated that there is a U-shaped association between HDL-C (high-density lipoprotein cholesterol) and the risk of cardiovascular events in male patients with hypertension. However, to the best of our knowledge, the relationship between HDL-C and intensive blood pressure control in specific cardiovascular events has never been investigated. To
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Effects of allisartan-isoproxil-based combination antihypertensive regimen in hypertensive patients with microalbuminuria or hyperuricemia J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-02-06 Ningling Sun, Hongyi Wang
Microalbuminuria and hyperuricemia management are crucial for the integrated management of hypertensive patients. This retrospective post hoc analysis aims to evaluate the optimal allisartan-isoproxil-based combination regimen for hypertensive patients with microalbuminuria or hyperuricemia. A total of 460 hypertensive patients with microalbuminuria and 486 hypertensive patients with hyperuricemia
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Cumulative blood pressure load and hypertensive nephropathy in Han Chinese hypertensive patients J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-31 Kuan-I Liu, Ming-Hui Hung, Chin-Chou Huang, Jaw-Wen Chen
The study aims to assess the relationship between cumulative blood pressure load (cBPL) and the risk of renal function decline in hypertensive patients and determine the blood pressure (BP) threshold required to prevent hypertensive nephropathy. A single-center prospective cohort study was conducted on hypertensive patients. The cBPL was defined as the proportion of area beyond variable BP cutoffs
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Efficacy of an enhanced recovery nursing plan as a rooming-in practice for women with preeclampsia post-cesarean section J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-23 Jing Li, Wan-Yuan Zhao, Ying Zhuang, Ning Gu, Meng-Qin Wang, Ya-Ning Zheng, Jie-Xun Wang
Our purpose was to develop and evaluate the clinical outcomes of a nursing plan as a rooming-in practice for enhanced recovery of women with preeclampsia following a cesarean section. The authors developed a postoperative enhanced recovery nursing plan as a rooming-in practice for women with preeclampsia based on summarizing evidence-based best practices. The authors used convenience sampling to select
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Association between triglyceride glucose index and depression in hypertensive population J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-19 Xin Zhang, Dan Zhao, Shanshan Guo, Jie Yang, Yang Liu
Growing evidence suggests that hypertensive individuals have a greater risk of developing depression, and depression can also increase the incidence of hypertension. In the hypertensive population, the association between triglyceride glucose (TyG) index and depression remains unclear. This study aimed to assess the association between TyG index and depression in hypertensive people through the cross-sectional
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Trends in blood pressure changes and hypertension prevalence in Australian adults before and during the COVID-19 pandemic J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-15 Janis M. Nolde, Fleur Streets, Denny Meyer, Won Sun Chen, Jiajun Wei, Nilmini Wickramasinghe, Patrick Hannebery, Gavin W. Lambert, Markus P. Schlaich
Efforts to limit the impact of the coronavirus disease (COVID-19) pandemic led to the implementation of public health measures and reallocation of health resources. To investigate trends in blood pressure (BP), hypertension and BMI in the Australian population during the COVID-19 pandemic, data from publicly accessible health stations were analyzed.
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Ambulatory arterial stiffness index, mortality, and adverse cardiovascular outcomes; Systematic review and meta-analysis J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-17 Christopher J. Boos, Aung Hein, Ahmed Khattab
The ambulatory arterial stiffness index (AASI) is a novel measure of both blood pressure (BP) variability and arterial stiffness. This systematic review and meta-analysis was designed to evaluate the strength of the association between AASI and mortality and major adverse cardiovascular events (MACE). PubMed, Scopus, CINAHL, Google Scholar. and the Cochrane library were searched for relevant studies
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Mid-term outcomes of total neointima implantation in surgical repair of acute type A aortic dissection J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-12 Yong Lin, Lin-feng Xie, Zhao-feng Zhang, Jian He, Xiao-fu Dai, Liang-wan Chen, Mei-fang Chen
Total neointima implantation (patch neointima technique + triple-branched stent graft placement) has been performed in proximal aortic repair for acute type A aortic dissection (ATAAD) for more than 10 years at a center. However, there is no report on the mid-term outcomes with a control group of the surgical procedure. Consequently, the authors aimed to evaluate the safety and efficacy of this technique
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Hypertensive disorders of pregnancy and midlife maternal cognition in a prospective cohort study J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-12 Kate Birnie, Janet Catov, Emma L. Anderson, Winok Lapidaire, Fanny Kilpi, Deborah A. Lawlor, Abigail Fraser
Hypertensive disorders of pregnancy (HDP) are associated with an increased risk of cardiovascular disorders, with recent evidence linking pre-eclampsia with vascular dementia. We examined associations of HDP with cognitive performance measured in midlife, in a prospective cohort study, the Avon Longitudinal Study of Parents and Children. Six cognitive function domains were measured 20 years after pregnancy
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The interpretable machine learning model associated with metal mixtures to identify hypertension via EMR mining method J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-12 Site Xu, Mu Sun
There are limited data available regarding the connection between hypertension and heavy metal exposure. The authors intend to establish an interpretable machine learning (ML) model with high efficiency and robustness that identifies hypertension based on heavy metal exposure. Our datasets were obtained from the US National Health and Nutrition Examination Survey (NHANES, 2013–2020.3). The authors
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Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-08 Ling Li, Bin Wu, Jiaoxuan Dong, Songbin He, Jie Xu, Gary Tse, Fangyu Dai, Haipeng Liu
Progressive cerebral infarction (PCI) is a common complication in patients with ischemic stroke that leads to poor prognosis. Blood pressure (BP) can indicate post-stroke hemodynamic changes which play a key role in the development of PCI. The authors aim to investigate the association between BP-derived hemodynamic parameters and PCI. Clinical data and BP recordings were collected from 80 patients
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Association between outdoor light at night and hypertension and high-normal blood pressure: A nationwide cross-sectional study among Chinese adults J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-08 Rui Wang, Xiangming Hu, Yanqiu Ou, Guoqiang Chen, Lebing Wang, Zhengmin Qian, Michael G. Vaughn, Maya Tabet, Liwen Hu, Guanghui Dong, Haojian Dong
The authors aimed to investigate the association between outdoor light at night (LAN) intensity and blood pressure. The study included 13 507 participants aged 45 and above from the 2011–2012 China Health and Retirement Longitudinal Study baseline survey. Blood pressure measurements were obtained by averaging the last two readings recorded (three measurements with an interval of 45–60 s between each
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Association of parity with the prevalence of hypertension in Japan: The Tohoku Medical Megabank Community-based cohort study J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-08 Hongxin Wang, Noriyuki Iwama, Keiichi Yuwaki, You Nakamichi, Hirotaka Hamada, Hasumi Tomita, Kazuma Tagami, Rie Kudo, Natsumi Kumagai, Hirohito Metoki, Naoki Nakaya, Atsushi Hozawa, Shinichi Kuriyama, Nobuo Yaegashi, Masatoshi Saito
This study investigated the association of parity with hypertension prevalence in Japanese women while considering a clinical history of hypertensive disorders of pregnancy (HDP) and menopausal status. This cross-sectional study included 30,530 Japanese women (6700 premenopausal; 23 830 postmenopausal). The association between parity and the prevalence of hypertension was evaluated using a multiple
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Pharmacist-led rapid medication titration for hypertension management by telehealth: A quality improvement initiative J. Clin. Hypertens. (IF 2.8) Pub Date : 2024-01-08 Anthony M. Ishak, Kenneth J. Mukamal, Julia M. Wood, Medha Vyavahare, Jennifer L. Cluett, Stephen P. Juraschek
Hypertension guidelines recommend team-based care for the treatment of high blood pressure (BP). Clinical pharmacists can help patients get to goal BP with rapid medication titration in conjunction with telehealth visits. We conducted a pharmacist-led home BP monitoring pilot program from June 2020 to September 2021. Forty-two patients with a SBP ≥140 despite using ≤2 antihypertensive medications were
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Mid-term efficacy of castor stent and in situ fenestration stent in the treatment of type B aortic dissection involving the left subclavian artery: A retrospective single-center study J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-12-28 Qingsong Wu, Lin-feng Xie, Huangwei Li, Yue Shen, Zhihuang Qiu, Liangwan Chen
To evaluate the midterm efficacy of the Castor stent (CS) versus in situ fenestration (ISF) for reconstructing the left subclavian artery (LSA) in patients with type B aortic dissection (TBAD).
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Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6-year prospective cohort study J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-12-22 Changqiang Yang, Yue Song, Xinquan Wang, Yi Yang, Yaqiong Zhou, Dan Wang, Jixin Hou, Peijian Wang
The authors aim to assess the correlation between hypertension and the triglyceride-glucose (TyG) index and its associated indices, and to compare their abilities to identify hypertension. Four thousand eight hundred and sixty-six non-hypertensive participants were enrolled from the China National Health Survey in 2009. The data on new-onset hypertension were gathered in both 2011 and 2015. The TyG
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Management of nocturnal hypertension: An expert consensus document from Chinese Hypertension League J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-12-21 Jing Liu, Yan Li, Xinjun Zhang, Peili Bu, Xueping Du, Lizheng Fang, Yingqing Feng, Yifang Guo, Fei Han, Yinong Jiang, Yuming Li, Jinxiu Lin, Min Liu, Wei Liu, Mingzhi Long, Jianjun Mu, Ningling Sun, Hao Wu, Jianhong Xie, Jingyuan Xie, Liangdi Xie, Jing Yu, Hong Yuan, Yan Zha, Yuqing Zhang, Shanzhu Zhu, Jiguang Wang
Nocturnal hypertension is highly prevalent among Chinese and Asian populations, which is mainly attributed to high salt intake and high salt sensitivity. Nocturnal hypertension increases the risk of cardiovascular and all-cause mortality, independent of daytime blood pressure (BP). However, it can usually be detected by 24-h ambulatory BP monitoring, rather than routine office or home BP measurement
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Multiple radiologist review of adrenal CT still frequently misses lateralized surgical primary aldosteronism J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-12-11 Darren Mah, Mark Kneteman, Stefan J. Przybojewski, Vamshi Kotha, Gregory A. Kline, Alexander A. Leung, C. Benny So
Patients with primary aldosteronism (PA) have increased morbidity and mortality compared to those with essential hypertension. Accurate detection of lateralized PA is important so that affected patients can receive potentially curative adrenalectomy. However, around 40% of patients with lateralized PA have “normal” adrenal glands on computed tomography (CT). Additional independent review of imaging
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Correction to “Association of adiposity indices with prehypertension among Chinese adults: A cross-sectional study” J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-29
Xiao M, Chen C, Wang J, et al. Association of adiposity indices with prehypertension among Chinese adults: A cross-sectional study. J Clin Hypertens (Greenwich). 2023;25(5):470−479. The authors have brought the following to our attention: The corresponding author has been changed to: Yingqing Feng, Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital
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Associations of genetic variations in the M3 receptor with salt sensitivity, longitudinal changes in blood pressure and the incidence of hypertension in Chinese adults J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-27 Xi Zhang, Shi Yao, Peng Bao, Mingfei Du, Guilin Hu, Chao Chu, Dan Wang, Chen Chen, Qiong Ma, Hao Jia, Yue Sun, Yu Yan, Yueyuan Liao, Zejiaxin Niu, Ziyue Man, Lan Wang, Weihua Gao, Hao Li, Jie Zhang, Wenjing Luo, Xin Wang, Yang Wang, Jianjun Mu
Recent studies have reported the role of the M3 muscarinic acetylcholine receptor (M3R), a member of the G-protein coupled receptor superfamily, encoded by the CHRM3 gene, in cardiac function and the regulation of blood pressure (BP). The aim of this study was to investigate the associations of CHRM3 genetic variants with salt sensitivity, longitudinal BP changes, and the development of hypertension
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Novel lipid biomarkers and ratios as risk predictors for premature coronary artery disease: A retrospective analysis of 2952 patients J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-20 Si Chen, Zhan Li, Haolong Li, Xiaoli Zeng, Hui Yuan, Yongzhe Li
This study examined the associations between emerging lipid biomarkers (small dense low-density lipoprotein cholesterol [sdLDL-C), lipoprotein(a) [Lp(a)], and free fatty acids [FFA]), two ratios (sdLDL-C/LDL-C and the triglyceride–glucose [TyG) index), and the Gensini score (GS) in patients with premature coronary artery disease (PCAD) in relation to the extent of coronary stenosis. The authors evaluated
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Association between bilirubin and chronic kidney disease in hypertensive patients: The China hypertension registry study J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-20 Peixu Zhao, Haitao Xu, Yumeng Shi, Xiaoli Song, Guosheng Qiu, Congcong Ding, Wei Zhou, Chao Yu, Tao Wang, Lingjuan Zhu, Huihui Bao, Xiaoshu Cheng
Limited data exists on the association between Direct bilirubin (DBIL) and Indirect bilirubin (IBIL) with the risk of chronic kidney disease (CKD) among patients with hypertension. This study aimed to assess the relationship between DBIL and IBIL with the risk of CKD in a cohort of Chinese adults diagnosed with hypertension. This study included 14 182 Chinese patients with hypertension between the
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Shapely additive values can effectively visualize pertinent covariates in machine learning when predicting hypertension J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-16 Alexander A. Huang, Samuel Y. Huang
Machine learning methods are widely used within the medical field to enhance prediction. However, little is known about the reliability and efficacy of these models to predict long-term medical outcomes such as blood pressure using lifestyle factors, such as diet. The authors assessed whether machine-learning techniques could accurately predict hypertension risk using nutritional information. A cross-sectional
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A nomogram-based model to predict postoperative transient neurological dysfunctions in patients receiving acute type A aortic dissection surgery J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-15 Xin-fan Lin, Lin-feng Xie, Jian He, Yu-ling Xie, Zhao-feng Zhang, Liang-wan Chen, Mei-fang Chen
The purposes of this study were to develop and validate a nomogram for predicting postoperative transient neurological dysfunctions (TND) in patients with acute type A aortic dissection (AAAD) who underwent modified triple-branched stent graft implantation. This retrospective study developed a nomogram-based model in a consecutive cohort of 146 patients. Patient characteristics, preoperative clinical
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Association of high-normal albuminuria and vascular aging: Hanzhong adolescent hypertension study J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-15 Ming-Fei Du, Yang Wang, Gui-Lin Hu, Dan Wang, Zi-Yue Man, Chao Chu, Yue-Yuan Liao, Chen Chen, Qiong Ma, Yu Yan, Hao Jia, Yue Sun, Xi Zhang, Wen-Jing Luo, Ming-Ke Chang, Jian-Jun Mu
Normoalbuminuria has recently been associated with increased cardiovascular risk, and vascular aging is proposed as the early manifestation of cardiovascular disease. Here, the authors aimed to examine the association of high-normal albuminuria and vascular aging in a Chinese cohort. From our previously established cohort, 1942 participants with estimated glomerular filtration rate ≥60 mL/min/1.73
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Association of an inter-arm systolic blood pressure difference with all-cause and cardiovascular mortality: A meta-analysis of cohort studies J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-09 Min Li, Fangfang Fan, Lin Qiu, Wei Ma, Yan Zhang
This meta-analysis evaluated the potential association of a simultaneously measured inter-arm systolic blood pressure difference (IASBPD) and all-cause mortality and cardiovascular mortality. The Medline, Cochrane Library, Embase, and PubMed databases were searched through to April 14, 2023 for relevant literature. The outcomes were the associations of IASBPD with all-cause and cardiovascular mortality
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Blood pressure and renal function responses in workers exposed to lead for up to six years J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-08 Yu-Ling Yu, De-Wei An, Wen-Yi Yang, Peter Verhamme, Karel Allegaert, Tim S. Nawrot, Jan A. Staessen
The Study for Promotion of Health in Recycling Lead (SPHERL) assessed the blood pressure (BP) and renal function (RF) responses for up to 6 years in the workers without previous occupational lead exposure. BP was the average of five consecutive readings and the estimated glomerular filtration rate was derived from serum creatinine (eGFRcrt) and cystatin C (eGFRcys). Blood lead (BL) was measured by
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GeogRaphic and socioecoNomic Distribution of real-world Indian data of home blood pressure monitoring (GRAND Study): Study protocol for an observational study in 18 medical centers across India J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-11-01 Narsingh Verma, Noriko Matsushita, Ebtehal Salman, Takayoshi Ohkubo, Yutaka Imai
One-fourth of death in India is attributed to cardiovascular disease (CVD) and more than 80% is related to ischemic heart disease and stroke. The main risk factor for CVD is hypertension. Every third person in India suffers from hypertension and the prevalence increased drastically in the past 20 years, especially among the youngest age group of 20 and 44 years. Regardless of being under anti-hypertension
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The HOPE Asia Network consensus on blood pressure measurements corresponding to office measurements: Automated office, home, and ambulatory blood pressures J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-10-25 Jinho Shin, Ji-Guang Wang, Yook-Chin Chia, Kazuomi Kario, Chen-Huan Chen, Hao-Min Cheng, Takeshi Fujiwara, Satoshi Hoshide, Minh Van Huynh, Yan Li, Michiaki Nagai, Jennifer Nailes, Sungha Park, Saulat Siddique, Jorge Sison, Arieska Ann Soenarta, Guru Prasad Sogunuru, Jam Chin Tay, Boon Wee Teo, Naoko Tomitani, Kelvin Tsoi, Yuda Turana, Narsingh Verma, Tzung-Dau Wang, Yuqing Zhang
For adopting recently introduced hypertension phenotypes categorized using office and out of office blood pressure (BP) for the diagnosis of hypertension and antihypertension drug therapy, it is mandatory to define the corresponding out of office BP with the specific target BP recommended by the major guidelines. Such conditions include white-coat hypertension (WCH), masked hypertension (MH), white-coat
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Real-world trends in pre-dialysis blood pressure levels of patients undergoing dialysis in Japan using a web-based national database J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-10-27 Hirofumi Sakuma, Motoki Matsuki, Naoyuki Hasebe, Naoki Nakagawa
The prevalence of hypertension is high among patients undergoing dialysis. We extracted data of patients undergoing dialysis between 2012 and 2020 with recorded pre-dialysis systolic blood pressure (SBP) using a web-based national database in Japan. Following the 2019 Japanese Society of Hypertension guidelines, we classified SBP and assessed its trends over time based on sex, age, diabetes status
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The left adrenal vein: An important direction for right adrenal venous sampling J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-10-26 Hongliang Xiong, Li Du, Jiao Yang, WeiTong Hu, JiaBing Huang, YunDe Li, Xi Chen, YiFei Dong
This study aimed to evaluate the guiding role of left adrenal vein (LAV) for right adrenal venous sampling (AVS). A total of 347 patients who were diagnosed with primary aldosteronism (PA) and underwent successful AVS procedures from January 2020 to July 2021 were retrospectively analyzed. According to the different quadrant position of the orifice of right adrenal vein (RAV), the area where the orifice
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Redefining primary hyperaldosteronism as “The Syndrome of Inappropriate Aldosterone Secretion (SIALDS)”: A common but unrecognized cause of hypertension J. Clin. Hypertens. (IF 2.8) Pub Date : 2023-10-25 Rajat Lamba
The current screening and diagnostic recommendations for detecting Primary Hyperaldosteronism (PHA) focus on diagnosing the more severe and overt instances of renin-independent aldosterone production. However, milder forms of autonomous aldosterone secretion have been demonstrated to exist below the diagnostic thresholds of current PHA guidelines, and associate with clinically relevant cardiovascular