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Alleviating iatrogenic effects of paclitaxel via antiinflammatory treatment Vasc. Med. (IF 3.5) Pub Date : 2024-04-16 Mengwei Zhang, Saran Lotfollahzadeh, Nagla Elzinad, Xiaosheng Yang, Murad Elsadawi, Adam C Gower, Mostafa Belghasem, Tarek Shazly, Vijaya B Kolachalama, Vipul C Chitalia
Background:Paclitaxel (PTX) is touted as an essential medicine due to its extensive use as a chemotherapeutic agent for various cancers and an antiproliferative agent for endovascular applications. Emerging studies in cardio-oncology implicate various vascular complications of chemotherapeutic agents.Methods:We evaluated the inflammatory response induced by the systemic administration of PTX. The investigation
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The impact of the Affordable Care Act Medicaid Expansion in Medicare beneficiaries with peripheral artery disease Vasc. Med. (IF 3.5) Pub Date : 2024-04-12 Stanislav Henkin, Stephen A Kearing, Pablo Martinez-Camblor, Nikolaos Zacharias, Mark A Creager, Michael N Young, Philip P Goodney, Jesse A Columbo
Background: In 2014, the Affordable Care Act Medicaid Expansion (ME) increased Medicaid eligibility for adults with an income level up to 138% of the federal poverty level. In this study, we examined the impact of ME on mortality and amputation in patients with peripheral artery disease (PAD). Methods: The 100% MedPAR and Part-B Carrier files from 2011 to 2018 were queried to identify all fee-for-service
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Independent association between IVC filter placement and VTE risk in patients with upper gastrointestinal bleeding and isolated distal DVT: A retrospective cohort study Vasc. Med. (IF 3.5) Pub Date : 2024-04-12 Ying Huang, Hailong Luo, Xin Liu, Yanlin Li, Jing Gong
Background:The placement of inferior vena cava (IVC) filters often emerges as an alternative preventative measure against pulmonary embolism in patients with upper gastrointestinal (GI) bleeding and isolated distal deep vein thrombosis (DVT). We aimed to investigate the association of IVC filter placement and the incidence of venous thromboembolism (VTE) recurrence in this patient population.Methods:We
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Urinary vanin-1 as a novel biomarker for survival in peripheral artery disease Vasc. Med. (IF 3.5) Pub Date : 2024-04-12 Bernhard Zierfuss, Anna Karlinger, Marija Bojic, Renate Koppensteiner, Gerit-Holger Schernthaner, Clemens Höbaus
Background:Chronic kidney disease is associated with increased rates of incidence, morbidity, and mortality in lower-extremity peripheral artery disease (PAD). No specific marker for a functional risk assessment of kidney disease in PAD is known, especially at the early stages. Thus, we speculated that urinary vanin-1 (uVNN1), a marker of oxidative stress even in early kidney injury, could further
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Sitting knee-flexion angle does not influence endothelial-dependent vasodilation in laboratory or free-living conditions Vasc. Med. (IF 3.5) Pub Date : 2024-04-10 Madeline E Shivgulam, Myles W O’Brien, Yanlin Wu, Haoxuan Liu, Jennifer L Petterson, Beverly D Schwartz, Derek S Kimmerly
Introduction:Single bouts of prolonged bent-legged sitting attenuate popliteal endothelial-dependent vasodilation (as assessed via flow-mediated dilation [FMD]), which is partially attributed to arterial ‘kinking’. However, the impact of knee-flexion angle on sitting-induced popliteal FMD is unknown. The objective of this study was to perform separate laboratory and free-living studies to test the
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Images in Vascular Medicine: Takayasu retinopathy as a primary presentation of active vasculitis Vasc. Med. (IF 3.5) Pub Date : 2024-04-04 Chinmay Mahatme, Virna M. Shah, Veerappan R. Saravanan
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Vascular Medicine Patient Information Page: Popliteal artery aneurysm Vasc. Med. (IF 3.5) Pub Date : 2024-04-04 Andrea D Kim, Alexandra L Solomon, Elizabeth V Ratchford
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Deep venous thrombosis in patients with atresia of the inferior vena cava and right kidney hypoplasia (KILT syndrome): Systematic review of the literature Vasc. Med. (IF 3.5) Pub Date : 2024-04-04 Nikola Pantic, Mirjana Cvetkovic, Jelena Milin-Lazovic, Jelica Vukmirovic, Aleksandar Pavlovic, Marijana Virijevic, Zlatko Pravdic, Sofija Kozarac, Nikica Sabljic, Nada Suvajdzic-Vukovic, Marko Dragas, Mirjana Mitrovic
Inferior vena cava (IVC) anomalies are uncommon congenital causes of deep vein thrombosis (DVT). KILT syndrome (kidney and IVC abnormalities with leg thrombosis) has only been described as case reports in the literature. Therefore, the characteristics, evaluation, and management of patients with KILT syndrome have not yet been standardized. This study aimed to systematically review and analyze the
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Pilot study to evaluate the safety and effectiveness of etidronate treatment for arterial calcification due to deficiency of CD73 (ACDC) Vasc. Med. (IF 3.5) Pub Date : 2024-04-03 Elisa A Ferrante, Cornelia D Cudrici, Mahmood Rashidi, Yi-Ping Fu, Rebecca Huffstutler, Katherine Carney, Marcus Y Chen, Cynthia St Hilaire, Kevin Smith, Hadi Bagheri, James D Katz, Carlos R Ferreira, William A Gahl, Manfred Boehm, Alessandra Brofferio
Background:Arterial calcification due to deficiency of CD73 (ACDC; OMIM 211800) is a rare genetic disease resulting in calcium deposits in arteries and small joints causing claudication, resting pain, severe joint pain, and deformities. Currently, there are no standard treatments for ACDC. Our previous work identified etidronate as a potential targeted ACDC treatment, using in vitro and in vivo disease
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Images in Vascular Medicine: Enterocolic lymphocytic phlebitis as a rare vascular cause of colitis Vasc. Med. (IF 3.5) Pub Date : 2024-04-01 Shantum Misra, Aaron Hakim, Martin P Smith, Vikram Deshpande, Jacqueline L Wolf, Brett J Carroll
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Association between carotid wall layers and invasively measured central blood pressure Vasc. Med. (IF 3.5) Pub Date : 2024-04-01 Daniel SS Mello, Silvio Gioppato, Diego Q Antoniassi, Demétrio CS Vieira, Pedro HA Matos, Silvério A Fernandes, Otavio R Coelho-Filho, Roberto Schreiber, Rogério TP Okawa, Andrei C Sposito, José R Matos-Souza, Wilson Nadruz
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Support and resources for patients with aortic disease Vasc. Med. (IF 3.5) Pub Date : 2024-03-28 April D. Shinske, Ellen Hostetler, Catherine Fowler, Gareth Owens, Chrisanne Campos, Victoria Hilton, Gretchen MacCarrick
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Five-year outcomes of the GORE VIABAHN Endoprosthesis for the treatment of complex femoropopliteal lesions from a Japanese postmarket surveillance study Vasc. Med. (IF 3.5) Pub Date : 2024-03-28 Osamu Iida, Takao Ohki, Yoshimitsu Soga, Nobuhiro Suematsu, Tatsuya Nakama, Terutoshi Yamaoka, Kazuki Tobita, Shigeo Ichihashi
Introduction: The safety and effectiveness of the GORE VIABAHN Endoprosthesis for treatment of symptomatic patients with peripheral artery disease (PAD) and complex femoropopliteal (FP) lesions was assessed in a real-world Japanese practice setting. Methods: A prospective, multicenter, postmarket surveillance study was conducted from 2016 to 2017 at 64 sites in Japan. Symptomatic patients with PAD
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Shaping the future of vascular care: The evolution of advanced practice providers (APPs) Vasc. Med. (IF 3.5) Pub Date : 2024-03-20 Alexandra Moran Baird, Katherine Hays, Danielle Vlazny
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Safety and effectiveness of the phoenix atherectomy device for endovascular treatment of common femoral and popliteal arteries: Results of the EN-MOBILE trial Vasc. Med. (IF 3.5) Pub Date : 2024-03-17 Christoph Schöfthaler, Nicola Troisi, Giovanni Torsello, Amila Jehn, Michael Lichtenberg, Jan C Karcher, Konstantinos Stavroulakis, Mario D’Oria, Athanasios Saratzis, Hany Zayed, Martin Andrassy, Grigorios Korosoglou
Background: This study aimed to assess the peri- and postprocedural outcomes of atherectomy-assisted endovascular treatment of the common femoral (CFA) and popliteal arteries. Methods: Phoenix atherectomy was used for the treatment of 73 and 53 de novo CFA and popliteal artery lesions, respectively, in 122 consecutive patients. Safety endpoints encompassed perforation and peripheral embolization. Postprocedural
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Methods, design, and initial results of an angiographic core lab from VOYAGER-PAD Vasc. Med. (IF 3.5) Pub Date : 2024-03-17 R Kevin Rogers, Joerg Herold, Nicholas Govsyeyev, Roberto Iezzi, Justin Morrison, Shea E Hogan, Mark Nehler, Rory Bricker, Brice Andring, Brian Bergmark, Matt Cavender, Emily Malgor, Donald Jacobs, Michael N Young, Warren Capell, Joseph W Yčas, Sonia S Anand, Scott D Berkowitz, E Sebastian Debus, Lloyd P Haskell, Eva Muehlhofer, Manesh R Patel, Connie N Hess, Rupert M Bauersachs, Victoria Anderson
Background: Anatomy is critical in risk stratification and therapeutic decision making in coronary disease. The relationship between anatomy and outcomes is not well described in PAD. We sought to develop an angiographic core lab within the VOYAGER-PAD trial. The current report describes the methods of creating this core lab, its study population, and baseline anatomic variables. Methods: Patients
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The time is now for vascular medicine Vasc. Med. (IF 3.5) Pub Date : 2024-03-15 Heather L Gornik, Raghu Kolluri, Herbert Aronow, Bruce Gray, Geno Merli, Ido Weinberg, Joshua A Beckman
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Vasa vasorum interna in the carotid wall of active forms of Takayasu arteritis evidenced by ultrasound localization microscopy Vasc. Med. (IF 3.5) Pub Date : 2024-03-15 Guillaume Goudot, Anatole Jimenez, Nassim Mohamedi, Jonas Sitruk, Louise Z Wang, Lina Khider, Patrick Bruneval, Emmanuel Messas, Mathieu Pernot, Tristan Mirault
Introduction: Takayasu arteritis (TA) is associated with microvascularization of the wall of large arteries and is related to inflammation. Ultrasound localization microscopy (ULM), combining ultrafast ultrasound imaging with microbubble (MB) injection, can track the path of MBs within the arterial wall and thus provide imaging of the vasa vasorum. From the analysis of MB tracks in the common carotid
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Accuracy of maximal acceleration time of pedal arteries to diagnose critical limb ischemia Vasc. Med. (IF 3.5) Pub Date : 2024-03-12 Jean-Eudes Trihan, Magali Croquette, Jeanne Hersant, Romain Prigent, Cedric Fontaine, Samir Henni, Damien Lanéelle
Introduction:Maximal acceleration time of distal arteries of the foot (ATmax) is correlated to ankle–brachial index (ABI) and toe–brachial index (TBI), and seems very promising in diagnosing severe peripheral artery disease (PAD) and especially critical limb-threatening ischemia (CLTI). Our goal was to confirm the cut-off value of 215 ms to predict a toe pressure (TP) ⩽ 30 mmHg.Methods:A 4-month retrospective
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Long-term outcome of percutaneous endovascular stenting in external iliac artery endofibrosis Vasc. Med. (IF 3.5) Pub Date : 2024-03-12 Mohsen Sharifi, Robert Snyder, Iman Sharifi, Emily White
Background:External iliac artery endofibrosis (EIAE) is a rare vascular disease which has been traditionally seen in avid cyclists. The conventional approach has been surgery, although no high-quality evidence suggests superiority of surgery over percutaneous endovascular intervention. There are limited data on the efficacy of stenting in EIAE.Methods:Over a 14-year period, we treated 10 patients (13
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Cardiovascular manifestations of Erdheim–Chester disease: A narrative review with two cases Vasc. Med. (IF 3.5) Pub Date : 2024-03-12 Alan Wong, Aditya Sharma, Randy Ramcharitar
Erdheim–Chester disease (ECD) is a rare ‘L’ (Langerhans) group histiocytic neoplasm that affects a multitude of organ systems, causing osteosclerotic bone lesions, periaortic encasement (‘coated’ aorta), retroperitoneal fibrosis involving kidneys and ureters (‘hairy kidney’), and infiltration of the central nervous system. Cardiovascular involvement can occur in up to 70% of patients and is usually
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Calprotectin as a new inflammatory marker of abdominal aortic aneurysm: A pilot study Vasc. Med. (IF 3.5) Pub Date : 2024-03-08 Emma Plana, Julia Oto, Raquel Herranz, Pilar Medina, Fernando Cana, Manuel Miralles
Introduction:Abdominal aortic aneurysm (AAA) is a relevant clinical problem due to the risk of rupture of progressively dilated infrarenal aorta. It is characterized by degradation of elastic fibers, extracellular matrix, and inflammation of the arterial wall. Though neutrophil infiltration is a known feature of AAA, markers of neutrophil activation are scarcely analyzed; hence, the main objective
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Three-year clinical course after fluoropolymer-based drug-eluting stent implantation for femoropopliteal lesions Vasc. Med. (IF 3.5) Pub Date : 2024-03-08 Osamu Iida, Mitsuyoshi Takahara, Yoshimitsu Soga, Terutoshi Yamaoka, Masahiko Fujihara, Daizo Kawasaki, Shigeo Ichihashi, Yasushi Sakata, Toshiaki Mano, Yoshiharu Higuchi
Background:Although the 1-year clinical outcomes of fluoropolymer-based drug-eluting stents (FP-DES) were favorable for the treatment of real-world femoropopliteal lesions in symptomatic peripheral artery disease (PAD), their performance beyond 1 year remained unknown. The current study determined the 3-year clinical course of FP-DES implantation for real-world femoropopliteal lesions.Methods:This
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Impact of comorbid opioid use disorder and major depressive disorder on healthcare utilization outcomes in patients with peripheral artery disease: A National Readmission Database analysis Vasc. Med. (IF 3.5) Pub Date : 2024-02-23 Kelvin Amenyedor, Megan Lee, Miguel Algara, Waleed Tariq Siddiqui, Madeleine Hardt, Gaëlle Romain, Carlos Mena-Hurtado, Kim G Smolderen
Background:Prior research has demonstrated that individuals with peripheral artery disease (PAD) often have comorbid opioid use disorder (OUD) and major depressive disorder (MDD), with limited data regarding their impact on readmission outcomes, length of stay, and cost. This study aimed to investigate these healthcare utilization outcomes in patients with PAD who have comorbid OUD and MDD.Methods:Data
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Capillaroscopic differences between primary Raynaud phenomenon and healthy controls indicate potential microangiopathic involvement in benign vasospasms Vasc. Med. (IF 3.5) Pub Date : 2024-02-09 Sophie Brunner-Ziegler, Eva Dassler, Markus Müller, Marco Pratscher, Nikolaus Franz-Ferdinand Maria Forstner, Renate Koppensteiner, Oliver Schlager, Bernd Jilma
Background:For primary Raynaud phenomenon (PRP), an otherwise unexplained vasospastic disposition is assumed. To test the hypothesis of an additional involvement of distinct ultrastructural microvascular alterations, we compared the nailfold capillary pattern of patients with PRP and healthy controls.Methods:A total of 120 patients with PRP (with a median duration of vasospastic symptoms of 60 [IQR:
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Evaluation of short-term mortality in patients with Medicare undergoing endovascular interventions for chronic limb-threatening ischemia Vasc. Med. (IF 3.5) Pub Date : 2024-02-09 Jacob Cleman, Gaëlle Romain, Santiago Callegari, Lindsey Scierka, Francky Jacque, Kim G Smolderen, Carlos Mena-Hurtado
Introduction:Patients with chronic limb-threatening ischemia (CLTI) have high mortality rates after revascularization. Risk stratification for short-term outcomes is challenging. We aimed to develop machine-learning models to rank predictive variables for 30-day and 90-day all-cause mortality after peripheral vascular intervention (PVI).Methods:Patients undergoing PVI for CLTI in the Medicare-linked
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Factors associated with false lumen changes in patients with superior mesenteric artery dissection Vasc. Med. (IF 3.5) Pub Date : 2024-02-09 Junhao Mei, Yuan Yuan, Hui Yan, Xi Zhao, Tongqing Xue, Haobo Su, Zhongzhi Jia
Background:False lumen changes (FLCs) are the main reference for the prognosis judgment and treatment plan selection for type IIa superior mesenteric artery dissection (SMAD).Methods:For this retrospective study, 55 patients with symptomatic type IIa SMAD were included. Computational fluid dynamics (CFD) analysis was used to explore the hemodynamic basis of FLCs. Correlation and multiple linear regression
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Venous thromboembolic outcomes in patients with lymphedema and lipedema: An analysis from the National Inpatient Sample Vasc. Med. (IF 3.5) Pub Date : 2024-02-09 Muhammad Umar Khalid, Sameer Prasada, Courtney Jennings, John R Bartholomew, Meghann McCarthy, Deborah A Hornacek, Douglas Joseph, Wei Chen, Graham Schwarz, Rohan Bhandari, Ayman Elbadawi, Scott J Cameron
Background:Patients with lymphedema and lipedema share physical exam findings that may lead to misdiagnosis. Poor mobility is common in patients with obesity and patients with lymphedema and lipedema. This may constitute a risk factor for venous thromboembolism (VTE). Our objective was to evaluate the association of VTE in obese patients with lymphedema and lipedema.Methods:The National Inpatient Sample
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Dysregulated platelet function in patients with postacute sequelae of COVID-19 Vasc. Med. (IF 3.5) Pub Date : 2024-02-09 Anu Aggarwal, Tamanna K Singh, Michael Pham, Matthew Godwin, Rui Chen, Thomas M McIntyre, Alliefair Scalise, Mina K Chung, Courtney Jennings, Mariya Ali, Hiijun Park, Kristin Englund, Alok A Khorana, Lars G Svensson, Samir Kapadia, Keith R McCrae, Scott J Cameron
Background:Postacute sequelae of COVID-19 (PASC), also referred to as “Long COVID”, sometimes follows COVID-19, a disease caused by SARS-CoV-2. Although SARS-CoV-2 is well known to promote a prothrombotic state, less is known about the thrombosis risk in PASC. Our objective was to evaluate platelet function and thrombotic potential in patients following recovery from SARS-CoV-2, but with clear symptoms
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Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm Vasc. Med. (IF 3.5) Pub Date : 2024-02-09 Yan Yan, Xuanfeng Qin, Yongtao Zheng, Tao Jin, Yuanyuan Hu, Qingzhu An, Bing Leng
Introduction:Intracranial aneurysm (IA) is a common vascular enlargement that occurs in the wall of cerebral vessels and frequently leads to fatal subarachnoid hemorrhage. PDZ and LIM domain protein 1 (PDLIM1) is a cytoskeletal protein that functions as a platform for multiple protein complex formation. However, whether PDLIM is involved in the pathogenesis of IA remains poorly understood.Methods:Loss-of-function
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Advances in lymphedema: An under-recognized disease with a hopeful future for patients Vasc. Med. (IF 3.5) Pub Date : 2024-01-03 Brett J Carroll, Dhruv Singhal
Lymphedema has traditionally been underappreciated by the healthcare community. Understanding of the underlying pathophysiology and treatments beyond compression have been limited until recently. Increased investigation has demonstrated the key role of inflammation and resultant fibrosis and adipose deposition leading to the clinical sequelae and associated reduction in quality of life with lymphedema
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Factor XI/XIa inhibitors for the prevention and treatment of venous and arterial thromboembolism: A narrative review. Vasc. Med. (IF 3.5) Pub Date : 2023-11-10 Swathi Prakash,Adriana C Mares,Mateo Porres-Aguilar,Debabrata Mukherjee,Geoffrey D Barnes
During the past decade, direct oral anticoagulants (DOACs) have advanced and simplified the prevention and treatment of venous thromboembolism (VTE). However, there remains a high incidence of bleeds, which calls for agents that have a reduced risk of bleeding. Factor XI (FXI) deficiency is associated with lower rates of venous thrombosis and stroke compared to the general population with a lower risk
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Images in Vascular Medicine: Migration of multiple venous stents into the heart. Vasc. Med. (IF 3.5) Pub Date : 2023-11-08 Akshaya Gadre,Emmanuel Daon,Adam S Alli,Kamal Gupta
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Impact of preexisting coronary artery and peripheral artery disease on outcomes in diabetic patients after kidney transplant. Vasc. Med. (IF 3.5) Pub Date : 2023-11-07 Sania Jiwani,Wan-Chi Chan,Monil Majmundar,Kunal N Patel,Harsh Mehta,Aditya Sharma,Gaurav Parmar,Mark Wiley,Peter Tadros,Eric Hockstad,Sri G Yarlagadda,Aditi Gupta,Kamal Gupta
BACKGROUND Atherosclerotic cardiovascular disease is highly prevalent in patients with end-stage kidney disease (ESKD). Kidney transplant (KT) improves patient survival and cardiovascular outcomes. The impact of preexisting coronary artery disease (CAD) and peripheral artery disease (PAD) on posttransplant outcomes remains unclear. METHODS This is a retrospective study utilizing the United States Renal
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Real-world effect of iloprost in patients with chronic limb-threatening ischemia (CLTI): A cohort study. Vasc. Med. (IF 3.5) Pub Date : 2023-11-07 Dari Loubna,Joël Constans,Carine Boulon,Caroline Caradu,François-Xavier Lapébie,Alessandra Bura-Rivière,Lucie Chastaingt,Philippe Lacroix,Julien Bezin,Antoine Pariente
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Japanese real-world population with chronic limb-threatening ischemia who meet the criteria of the BEST-CLI trial. Vasc. Med. (IF 3.5) Pub Date : 2023-10-31 Yosuke Hata,Osamu Iida,Shin Okamoto,Takayuki Ishihara,Takuya Tsujimura,Naoko Higashino,Taku Toyoshima,Sho Nakao,Mitsuyoshi Takahara,Toshiaki Mano
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Primary results of the SAVAL randomized trial of a paclitaxel-eluting nitinol stent versus percutaneous transluminal angioplasty in infrapopliteal arteries. Vasc. Med. (IF 3.5) Pub Date : 2023-10-16 Hans van Overhagen,Masato Nakamura,Patrick J Geraghty,Sid Rao,Max Arroyo,Yoshimitsu Soga,Osamu Iida,Ehrin Armstrong,Tatsuya Nakama,Masahiko Fujihara,Mohammad M Ansari,Santhosh J Mathews,Yann Gouëffic,Michael R Jaff,Ido Weinberg,Duane S Pinto,Norihiko Ohura,Kara Couch,Jihad A Mustapha
BACKGROUND Effective and durable options for infrapopliteal artery revascularization for patients with chronic limb-threatening ischemia (CLTI) are limited. METHODS The SAVAL trial is a prospective, multicenter, randomized trial of patients with CLTI and infrapopliteal artery lesions with total lesion length ⩽ 140 mm, stenosis ⩾ 70%, and Rutherford category 4-5 assigned 2:1 to treatment with the SAVAL
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The conundrum of below the knee (BTK) drug delivery. Vasc. Med. (IF 3.5) Pub Date : 2023-10-16 Peter A Schneider
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National survey of patient symptoms and therapies among 707 women with a lipedema phenotype in the United States. Vasc. Med. (IF 3.5) Pub Date : 2023-10-16 Aaron W Aday,Paula Mc Donahue,Maria Garza,Vanessa N Crain,Niral J Patel,John A Beasley,Karen L Herbst,Joshua A Beckman,Shannon L Taylor,Michael Pridmore,Sheau-Chiann Chen,Manus J Donahue,Rachelle Crescenzi
BACKGROUND National survey data exploring the patient experience with lipedema are lacking. METHODS We conducted national surveys from 2016 to 2022 of women with lipedema as well as female controls. Surveys collected information on symptomatology, pain, and therapies. We performed logistic regression comparing symptoms among those with lipedema versus controls adjusting for age and BMI. RESULTS A total
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Low-intensity resistance exercise with blood flow restriction for patients with claudication: A randomized controlled feasibility trial. Vasc. Med. (IF 3.5) Pub Date : 2023-10-11 Thomas Parkington,David Broom,Thomas Maden-Wilkinson,Shah Nawaz,Markos Klonizakis
BACKGROUND Claudication is a common and debilitating symptom of peripheral artery disease, resulting in poor exercise performance and quality of life (QoL). Supervised exercise programs are an effective rehabilitation for patients with claudication, but they are poorly adhered to, in part due to the high pain and effort associated with walking, aerobic, and resistance exercise. Low-intensity resistance
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Noninvasive and invasive imaging of lower-extremity acute and chronic venous thrombotic disease. Vasc. Med. (IF 3.5) Pub Date : 2023-10-04 Xin Li,Christer Ruff,Vasileios Rafailidis,Gerd Grozinger,Demosthenes Cokkinos,Levester Kirksey,Abraham Levitin,Sameer Gadani,Sasan Partovi
The spectrum of venous thromboembolic (VTE) disease encompasses both acute deep venous thrombosis (DVT) and chronic postthrombotic changes (CPC). A large percentage of acute DVT patients experience recurrent VTE despite adequate anticoagulation, and may progress to CPC. Further, the role of iliocaval venous obstruction (ICVO) in lower-extremity VTE has been increasingly recognized in recent years.
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Cause of death in patients with acute pulmonary embolism. Vasc. Med. (IF 3.5) Pub Date : 2023-09-27 William Earle,Shantum Misra,Alexander Wester,Matthew Herzig,George Abdallah,Charles B Ross,Eric A Secemsky,Brett J Carroll
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Fluoroquinolones increase susceptibility to aortic aneurysm and aortic dissection: Molecular mechanism and clinical evidence. Vasc. Med. (IF 3.5) Pub Date : 2023-09-27 Xuezhen Xuan,Yaling Li,Genmao Cao,Ruijing Zhang,Jie Hu,Haijiang Jin,Honglin Dong
Aortic aneurysm (AA) and aortic dissection (AD) are prevalent severe cardiovascular diseases that result in catastrophic complications and unexpected deaths. Owing to the lack of clinically established and effective medications, the only treatment options are open surgical repair or endovascular therapy. Most researchers have focused on the development of innovative medications or therapeutic targets
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Investigating the impact of suboptimal prescription of preoperative antiplatelets and statins on race and ethnicity-related disparities in major limb amputation. Vasc. Med. (IF 3.5) Pub Date : 2023-09-22 Corey A Kalbaugh,Brian Witrick,Kerry A Howard,Laksika Banu Sivaraj,Katharine L McGinigle,William P Robinson,Samuel Cykert,Caitlin W Hicks,Catherine R Lesko
BACKGROUND Non-Hispanic Black and Hispanic patients with symptomatic PAD may receive different treatments than White patients with symptomatic PAD. The delivery of guideline-directed medical treatment may be a modifiable upstream driver of race and ethnicity-related disparities in outcomes such as limb amputation. The purpose of our study was to investigate the prescription of preoperative antiplatelets
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Images in Vascular Medicine: A case of recurrent hemorrhagic bullae from enoxaparin and then fondaparinux. Vasc. Med. (IF 3.5) Pub Date : 2023-09-12 Atefeh Ghorbanzadeh,Damon Houghton
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SVM Communications: Venous Taskforce update and Society announcements. Vasc. Med. (IF 3.5) Pub Date : 2023-09-05 Syed T Ahsan,Omar Esponda,Wenzhu Li,Reza Amini,Maxim Shaydakov,Jason Wheeler,Eri Fukaya
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Images in Vascular Medicine: Valsalva purpura secondary to balloon occlusion of the cavoatrial junction during intervention for lead-induced SVC syndrome. Vasc. Med. (IF 3.5) Pub Date : 2023-08-31 Calvin C Sheng,Bruce L Wilkoff,Sean P Lyden,Edward Soltesz,Scott J Cameron,Aravinda Nanjundappa
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Prevalence of dilated mid-ascending aorta in individuals 15 years and older: In search of optimal diagnostic criteria and their effect on the burden of disease. Vasc. Med. (IF 3.5) Pub Date : 2023-08-30 Mirza Mujadil Ahmad,Ji Ae Yoon,Muhammad Nabeel Syed,Mirza Nubair Ahmad,Sharmeen Fatima Hussaini,Mustafa Noor Muhammad,Syed Haris A Pir,Bijoy K Khandheria,A Jamil Tajik,Khawaja Afzal Ammar
BACKGROUND Controversy regarding the definition of the upper limit of normal (ULN) for dilated mid-ascending aorta (mAA) stems from variation in criteria, based on several small-sized studies with small datasets of normal subjects (DONS). The present study was carried out to demonstrate this variation in the prevalence of mAA dilation and to identify the optimal definition by creating the largest DONS
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Time-course evolution of functional performance during a 3-month supervised exercise training program in patients with symptomatic peripheral artery disease. Vasc. Med. (IF 3.5) Pub Date : 2023-08-29 Stefano Lanzi,Anina Pousaz,Luca Calanca,Lucia Mazzolai
INTRODUCTION Functional performance is impaired in patients with peripheral artery disease (PAD). The effects of a supervised exercise training (SET) program on functional performance have yet to be clearly determined. The aim was to investigate the time-course evolution of functional performance during a 3-month SET program. METHODS Patients with chronic symptomatic PAD participating in a 3-month
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Examining health care access disparities in Hispanic populations with peripheral artery disease and diabetes. Vasc. Med. (IF 3.5) Pub Date : 2023-08-29 Sebouh Bazikian,Diego Urbina,Chiu-Hsieh Hsu,Karla A Gonzalez,Emily R Rosario,Dan I Chu,Jennifer Tsui,Tze-Woei Tan
INTRODUCTION This study investigated disparities in health care access for Hispanic adults with diabetes and peripheral artery disease (PAD) who are at risk of lower-extremity amputation and other cardiovascular morbidities and mortalities. METHODS We utilized the health care access survey data from the All of Us research program to examine adults (⩾ 18 years) with either diabetes and/or PAD. The primary
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Longitudinal outcomes following peripheral vascular intervention among older persons living with HIV. Vasc. Med. (IF 3.5) Pub Date : 2023-08-28 Katherine Kentoffio,Tianyu Sun,Jiaman Xu,Rushi V Parikh,Priscilla Y Hsue,Eric A Secemsky
BACKGROUND Persons living with human immunodeficiency virus (HIV, PLWH) have an increased risk of peripheral artery disease (PAD) in comparison to the general population. However, a gap remains in understanding optimal management for this condition. This study assesses longitudinal outcomes associated with peripheral endovascular intervention (PVI) for PAD among PLWH. METHODS All Medicare fee-for-service
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Patient knowledge and preferences for peripheral artery disease treatment. Vasc. Med. (IF 3.5) Pub Date : 2023-08-28 Kim G Smolderen,Gaëlle Romain,Kensey Gosch,Ahmad Arham,Jeremy B Provance,John A Spertus,Anwesh B Poosala,Mehdi H Shishehbor,David Safley,Kate Scott,Nancy Stone,Carlos Mena-Hurtado
BACKGROUND Shared medical decision making requires patients' understanding of their disease and its treatment options. Peripheral artery disease (PAD) is a condition for which preference-sensitive treatments are available, but for which little is known about patients' knowledge and treatment preferences as it relates to specific treatment goals. METHODS In a prospective, multicenter registry that involved
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Hospitalizations during home-based walking exercise interventions in peripheral artery disease: Results from two randomized clinical trials. Vasc. Med. (IF 3.5) Pub Date : 2023-08-25 Neela D Thangada,Shujun Xu,Lu Tian,Lihui Zhao,Michael H Criqui,Luigi Ferrucci,W Jack Rejeski,Christiaan Leeuwenburgh,Todd Manini,Bonnie Spring,Diane Treat-Jacobson,Daniel E Forman,Lydia Bazzano,Jack Guralnik,Robert Sufit,Tamar Polonsky,Melina R Kibbe,Mary M McDermott
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Prevalence of extracoronary vascular abnormalities does not vary by age of presentation in patients with spontaneous coronary artery dissection (SCAD). Vasc. Med. (IF 3.5) Pub Date : 2023-08-25 Jacqueline M Visina,Nowrin Haque,Shi Huang,Aaron W Aday,Esther Sh Kim
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Vascular Disease Patient Information Page: Genetic testing for inherited vascular diseases associated with aneurysm and dissection. Vasc. Med. (IF 3.5) Pub Date : 2023-08-23 Gretchen MacCarrick,Elizabeth V Ratchford
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Ultrasound-detected tibial artery calcification as a marker of cardiovascular and lower-limb risk in asymptomatic patients with type-2 diabetes. Vasc. Med. (IF 3.5) Pub Date : 2023-08-23 Laurence Salle,Julien Magne,Angeladine Kenne Malaha,Lucie Chastaingt,Sophie Galinat,Anne Drutel,Philippe Lacroix,Marie-Pierre Teissier-Clément,Victor Aboyans
BACKGROUND Medial arterial calcification (MAC) is a vascular disease distinct from atherosclerosis. Recently, several studies have demonstrated that MAC is an important marker of cardiovascular events. We aim to assess the presence of MAC during ultrasound screening of lower-limb vasculature and its association with both cardiovascular (CV) and lower-limb events in patients with type-2 diabetes. METHODS
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Images in Vascular Medicine: Subcutaneous panniculitis-like T-cell lymphoma mimicking lipodermatosclerosis. Vasc. Med. (IF 3.5) Pub Date : 2023-08-21 Cathleen V D'Angelo,Seth Bendo,Samir Patel,Mitch Silver,Raghu Kolluri
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Images in Vascular Medicine: A strange case of painful lower-extremity lymphedema, skin thickening, and clubbing related to adenocarcinoma of the lung. Vasc. Med. (IF 3.5) Pub Date : 2023-08-14 Steven M Dean