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TABERNACL: Temporary Hemodynamic Stabilization In Vivo Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-27 Rim N. Halaby, Christopher G. Bruce, D. Korel Yildirim, Dogangun Uzun, Toby Rogers, Jaffar M. Khan, Andi E. Jaimes, Laurie P. Grant, Vasilis C. Babaliaros, Adam B. Greenbaum, Robert J. Lederman
BACKGROUND:Acute aortic regurgitation is life-threatening with few nonsurgical options for immediate stabilization. We propose Trans-Aortic Balloon to Ease Regurgitation Applying Counter-Pulsation (TABERNACL), a simple, on-table temporary valve using commercially available equipment to temporize acute severe aortic regurgitation.METHODS:We hypothesize that an appropriately sized commercial balloon
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ACURATE neo2 Versus SAPIEN 3 Ultra Transcatheter Heart Valve in Severe Aortic Valve Calcification: A Propensity-Matched Analysis Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-26 Clemens Eckel, Won-Keun Kim, Dagmar Sötemann, Christina Grothusen, Vedat Tiyerili, Guido Dohmen, Matthias Renker, Efstratios I. Charitos, Christian W. Hamm, Yeong-Hoon Choi, Albrecht Elsässer, Helge Möllmann, Johannes Blumenstein
BACKGROUND:Comparative data on transcatheter self-expanding ACURATE neo2 (NEO2) and balloon-expandable SAPIEN 3 Ultra prostheses in technically challenging anatomy of severe aortic valve calcified aortic annuli are scarce.METHODS:A total of 1987 patients with severe native aortic stenosis treated with the self-expanding NEO2 (n=1457) or balloon-expandable SAPIEN 3 Ultra (n=530) from January 2017 to
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Optical Coherence Tomography–Based Functional Stenosis Assessment: FUSION—A Prospective Multicenter Trial Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-25 Allen Jeremias, Akiko Maehara, Mitsuaki Matsumura, Richard A. Shlofmitz, Aziz Maksoud, Takashi Akasaka, Hiram G. Bezerra, William F. Fearon, Habib Samady, Bruce Samuels, Joshua Rapkin, Ajay Gopinath, Nutte Tarn Teraphongphom, Jana Buccola, Ziad A. Ali
BACKGROUND:Intravascular imaging and intracoronary physiology may both be used to guide and optimize percutaneous coronary intervention; however, they are rarely used together. The virtual flow reserve (VFR) is an optical coherence tomography (OCT)–based model of fractional flow reserve (FFR) facilitating the assessment of the physiological significance of coronary lesions. We aimed to validate the
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Impact of Incomplete Revascularization After PCI in Left Main Disease: The EXCEL Trial Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-19 Ziad A. Ali, Javier Jas Garcia, Keyvan Karimi Galougahi, Jennifer Horst, Anthony Gallo, Doosup Shin, Ori Ben-Yehuda, Shmuel Chen, Björn Redfors, Arie Pieter Kappetein, SabikJoseph F. III, Patrick W. Serruys, Gregg W. Stone
BACKGROUND:The importance of complete revascularization after percutaneous coronary intervention (PCI) in patients with left main coronary artery disease is uncertain. We investigated the clinical impact of complete revascularization in patients with left main coronary artery disease undergoing PCI in the EXCEL trial (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left
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Redo-TAVR Feasibility After SAPIEN 3 Stratified by Implant Depth and Commissural Alignment: A CT Simulation Study Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-19 Anoop N. Koshy, Gilbert H.L. Tang, Sahil Khera, Manish Vinayak, Megan Berdan, Sneha Gudibendi, Amit Hooda, Lucy Safi, Stamatios Lerakis, George D. Dangas, Samin K. Sharma, Annapoorna S. Kini, Parasuram Krishnamoorthy
BACKGROUND:Redo-transcatheter aortic valve replacement (TAVR) can pin the index transcatheter heart valve leaflets open leading to sinus sequestration and restricting coronary access. The impact of initial implant depth and commissural alignment on redo-TAVR feasibility is unclear. We sought to determine the feasibility of redo-TAVR and coronary access after SAPIEN 3 (S3) TAVR stratified by implant
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No-Reflow Prediction in Acute Coronary Syndrome During Percutaneous Coronary Intervention: The NORPACS Risk Score Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-15 Luke P. Dawson, Muhammad Rashid, Diem T. Dinh, Angela Brennan, Jason E. Bloom, Sinjini Biswas, Jeffrey Lefkovits, James A. Shaw, William Chan, David J. Clark, Ernesto Oqueli, Chin Hiew, Melanie Freeman, Andrew J. Taylor, Christopher M. Reid, Andrew E. Ajani, David M. Kaye, Mamas A. Mamas, Dion Stub, on behalf of the MIG and BCIS Investigators
BACKGROUND:Suboptimal coronary reperfusion (no reflow) is common in acute coronary syndrome percutaneous coronary intervention (PCI) and is associated with poor outcomes. We aimed to develop and externally validate a clinical risk score for angiographic no reflow for use following angiography and before PCI.METHODS:We developed and externally validated a logistic regression model for prediction of
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Comparison of Transcatheter Edge-to-Edge Mitral Valve Repair for Primary Mitral Regurgitation Outcomes to Hospital Volumes of Surgical Mitral Valve Repair Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-03-04 Paul A. Grayburn, Michael J. Mack, Pratik Manandhar, Andrzej S. Kosinski, Anna Sannino, Robert L. Smith II, Molly Szerlip, Sreekanth Vemulapalli
BACKGROUND:Transcatheter edge-to-edge mitral valve (MV) repair (TEER) is an effective treatment for patients with primary mitral regurgitation at prohibitive risk for surgical MV repair (MVr). High-volume MVr centers and high-volume TEER centers have better outcomes than low-volume centers, respectively. However, whether MVr volume predicts TEER outcomes remains unknown. We hypothesized that high-volume
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Clinical Outcomes and Predictors of Advanced Therapy for the Management of Right Heart Thrombus Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-02-27 Nathan W. Watson, Ido Weinberg, Andrew B. Dicks, Brett J. Carroll, Eric A. Secemsky
Background:The role of advanced therapies (systemic thrombolysis, catheter-based treatment, and surgical thrombectomy) for the management of right heart thrombus is poorly defined. In this study, we assessed the clinical predictors and outcomes of advanced therapy compared with anticoagulation alone for the acute management of right heart thrombus.Methods:In this observational cohort study, we analyzed
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Implementation of a Multidimensional Strategy to Reduce Post-PCI Bleeding Risk Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-02-27 Andrea L. Price, Amit P. Amin, Susan Rogers, John C. Messenger, Issam D. Moussa, Julie M. Miller, Jonathan Jennings, Frederick A. Masoudi, J. Dawn Abbott, Rebecca Young, Daniel M. Wojdyla, Sunil V. Rao
BACKGROUND:The American College of Cardiology Reduce the Risk: PCI Bleed Campaign was a hospital-based quality improvement campaign designed to reduce post-percutaneous coronary intervention (PCI) bleeding events. The aim of the campaign was to provide actionable evidence-based tools for participants to review, adapt, and adopt, depending upon hospital resources and engagement.METHODS:We used data
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Percutaneous Left Ventricular Unloading During High-Risk Coronary Intervention: Rationale and Design of the CHIP-BCIS3 Randomized Controlled Trial Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-02-27 Matthew Ryan, Saad M. Ezad, Ian Webb, Peter D. O’Kane, Matthew Dodd, Richard Evans, Lynn Laidlaw, Sohail Q. Khan, Roshan Weerackody, Alan Bagnall, Vasileios F. Panoulas, Haseeb Rahman, Julian W. Strange, Farzin Fath-Ordoubadi, Stephen P. Hoole, Rod H. Stables, Nick Curzen, Tim Clayton, Divaka Perera, on behalf of the CHIP-BCIS3 Investigators
INTRODUCTION:Percutaneous coronary intervention for complex coronary disease is associated with a high risk of cardiogenic shock. This can cause harm and limit the quality of revascularization achieved, especially when left ventricular function is impaired at the outset. Elective percutaneous left ventricular unloading is increasingly used to mitigate adverse events in patients undergoing high-risk
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Angiography-Derived Index of Microcirculatory Resistance to Define the Risk of Early Discharge in STEMI Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-02-20 Roberto Scarsini, Rafail A. Kotronias, Francesco Della Mora, Leonardo Portolan, Stefano Andreaggi, Stefano Benenati, Federico Marin, Sara Sgreva, Alberto Comuzzi, Caterina Butturini, Gabriele Pesarini, Domenico Tavella, Keith M. Channon, Hector M. Garcia Garcia, Flavio Ribichini, Adrian P. Banning, Giovanni Luigi De Maria
BACKGROUND:Patients with ST-segment–elevation myocardial infarction but no coronary microvascular injury are at low risk of early cardiovascular complications (ECC). We aim to assess whether nonhyperemic angiography-derived index of microcirculatory resistance (NH-IMRangio) could be a user-friendly tool to identify patients at low risk of ECC, potentially candidates for expedited care pathway and early
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Statewide Initiative to Reduce Patient Radiation Doses During Percutaneous Coronary Intervention Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-02-13 Ryan D. Madder, Milan Seth, Kathleen Frazier, Simon Dixon, Milind Karve, John Collins, Ronald V. Miller, Elizabeth Pielsticker, Manoj Sharma, Devraj Sukul, Hitinder S. Gurm
BACKGROUND:Improved radiation safety practices are needed across hospitals performing percutaneous coronary intervention (PCI). This study was performed to assess the temporal trend in PCI radiation doses concurrent with the conduct of a statewide radiation safety initiative.METHODS:A statewide initiative to reduce PCI radiation doses was conducted in Michigan between 2017 and 2021 and included focused
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Five-Year Safety and Effectiveness of Paclitaxel Drug-Coated Balloons Alone or With Provisional Bare Metal Stenting for Real-World Femoropopliteal Lesions: IN.PACT Global Study Subgroup Analysis Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-02-13 Gary M. Ansel, Marianne Brodmann, Krishna J. Rocha-Singh, Jeremiah S. Menk, Thomas Zeller, for the IN.PACT Global Study Investigators
BACKGROUND:The treatment of complex infra-inguinal disease with drug-coated balloons (DCBs) is associated with a significant number of patients undergoing provisional stenting to treat a suboptimal result. To determine the potential long-term impact of DCB treatment with provisional bare metal stenting in complex lesions in real-world patients, a post hoc analysis was performed on data from the IN
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Reperfusion in Patients With ST-Segment–Elevation Myocardial Infarction With Cardiogenic Shock and Prolonged Interhospital Transport Times Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-01-31 Sean van Diepen, Yinggan Zheng, Janek M. Senaratne, Benjamin D. Tyrrell, Debraj Das, Holger Thiele, Timothy D. Henry, Kevin R. Bainey, Robert C. Welsh
BACKGROUND:In patients with ST-segment–elevation myocardial infarction complicated by cardiogenic shock, primary percutaneous coronary intervention (pPCI) is the preferred revascularization option. Little is known about the efficacy and safety of a pharmacoinvasive approach for patients with cardiogenic shock presenting to a non-PCI hospital with prolonged interhospital transport times.METHODS:In a
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Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE) Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-01-24 Keith M. Sterling, Samuel Z. Goldhaber, Andrew S.P. Sharp, Nils Kucher, Noah Jones, Robert Maholic, Nicolas Meneveau, David Zlotnick, Sameh Sayfo, Stavros V. Konstantinides, Gregory Piazza
BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations. However, utilization and safety of such strategies in broader PE populations remain unclear. The KNOCOUT PE (The EKoSoNic Registry of the
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Catheterization for Congenital Heart Disease Adjustment for Risk Method II Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-01-23 Brian P. Quinn, Lauren C. Gunnelson, Sarah G. Kotin, Kimberlee Gauvreau, Mary J. Yeh, Babar Hasan, John Lozier, Oliver M. Barry, Shabana Shahanavaz, Sarosh P. Batlivala, Arash Salavitabar, Susan Foerster, Bryan Goldstein, Abhay Divekar, Ralf Holzer, George T. Nicholson, Michael L. O’Byrne, Wendy Whiteside, Lisa Bergersen
BACKGROUND:Current metrics used to adjust for case mix complexity in congenital cardiac catheterization are becoming outdated due to the introduction of novel procedures, innovative technologies, and expanding patient subgroups. This study aims to develop a risk adjustment methodology introducing a novel, clinically meaningful adverse event outcome and incorporating a modern understanding of risk.METHODS:Data
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Single Bolus r-SAK Before Primary PCI for ST-Segment–Elevation Myocardial Infarction Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-01-23 Pengsheng Chen, John W. Eikelboom, Chunyue Tan, Wenhao Zhang, Yi Xu, Jianling Bai, Jun Wang, Tong Wang, Xiaoxuan Gong, Kun Liu, Xin Chen, Xiaoyan Wang, Li Zhu, Xin Zhao, Naiquan Yang, Jun Jiang, Jun Pu, Bo Zhao, Zengguang Chen, Baihong Li, Guoyu Wang, Chuan Lu, Lianghong Ying, Meng Jiang, Xiaomei Zhu, Jiazheng Ma, Zhou Dong, Chen Li, Jiaxin Zong, Fumin Zhang, Jun Zhu, Jun Huang, Xiangqing Kong, Hao
BACKGROUND:It is uncertain whether adjunctive thrombolysis is beneficial for patients with ST-segment–elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) within 120 minutes of presentation. This study was to determine whether in patients presenting with ST-segment–elevation myocardial infarction a single bolus recombinant staphylokinase (r-SAK) before timely PCI leads
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Associations of Sarcopenia and Body Composition Measures With Mortality After Transcatheter Aortic Valve Replacement Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-01-18 Elliot J. Stein, Colin Neill, Sangeeta Nair, J. Greg Terry, J. Jeffrey Carr, William F. Fearon, Sammy Elmariah, Juyong B. Kim, Samir Kapadia, Dharam J. Kumbhani, Linda Gillam, Brian Whisenant, Nishath Quader, Alan Zajarias, Frederick G. Welt, Anthony A. Bavry, Megan Coylewright, Robert Piana, Ravinder R. Mallugari, Anna Vatterott, Natalie Jackson, Shi Huang, Brian R. Lindman
Background:Frailty associates with worse outcomes after transcatheter aortic valve replacement (TAVR). Sarcopenia underlies frailty, but the association between a comprehensive assessment of sarcopenia—muscle mass, strength, and performance—and outcomes after TAVR has not been examined.Methods:From a multicenter prospective registry of patients with symptomatic severe aortic stenosis undergoing TAVR
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Implications of Mitral Annular Calcification on Outcomes Following Mitral Transcatheter Edge-to-Edge Repair Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2024-01-18 Alon Shechter, Mirae Lee, Danon Kaewkes, Vivek Patel, Ofir Koren, Tarun Chakravarty, Keita Koseki, Takashi Nagasaka, Sabah Skaf, Moody Makar, Raj R. Makkar, Robert J. Siegel
BACKGROUND:Limited data exist regarding the impact of mitral annular calcification (MAC) on outcomes of transcatheter edge-to-edge repair for mitral regurgitation (MR).METHODS:We retrospectively analyzed 968 individuals (median age, 79 [interquartile range, 70–86] years; 60.0% males; 51.8% with functional MR) who underwent an isolated, first-time intervention. Stratified by MAC extent per baseline
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Impact of Transjugular Intracardiac Echocardiography-Guided Self-Expandable Transcatheter Aortic Valve Implantation on Reduction of Conduction Disturbances Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-12-28 Kenichi Ishizu, Shinichi Shirai, Norihisa Miyawaki, Kenji Nakano, Tadatomo Fukushima, Euihong Ko, Yasuo Tsuru, Hiroaki Tashiro, Hiroyuki Tabata, Miho Nakamura, Toru Morofuji, Takashi Morinaga, Masaomi Hayashi, Akihiro Isotani, Nobuhisa Ohno, Shinichi Kakumoto, Kenji Ando
BACKGROUND:A high permanent pacemaker implantation (PPI) risk remains a concern of self-expandable transcatheter aortic valve implantation, despite the continued improvements in implantation methodology. We aimed to assess the impact of real-time direct visualization of the membranous septum using transjugular intracardiac echocardiography (ICE) during transcatheter aortic valve implantation on reducing
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Clinical Outcomes of Deferred Lesions by IVUS Versus FFR-Guided Treatment Decision. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-29 Joo Myung Lee,Hangyul Kim,David Hong,Doyeon Hwang,Jinlong Zhang,Xinyang Hu,Jun Jiang,Chang-Wook Nam,Joon-Hyung Doh,Bong-Ki Lee,Weon Kim,Jinyu Huang,Fan Jiang,Hao Zhou,Peng Chen,Lijiang Tang,Wenbing Jiang,Xiaomin Chen,Wenming He,Jeehoon Kang,Sung-Gyun Ahn,Myeong-Ho Yoon,Ung Kim,You-Jeong Ki,Eun-Seok Shin,Ki Hong Choi,Taek Kyu Park,Jeong Hoon Yang,Young Bin Song,Seung-Hyuk Choi,Hyeon-Cheol Gwon,Bon-Kwon
BACKGROUND There are limited data regarding the safety of deferral of percutaneous coronary intervention based on intravascular ultrasound (IVUS) findings. The current study sought to compare the prognosis between deferred lesions based on IVUS and fractional flow reserve (FFR)-guided treatment decision. METHODS This study is a post hoc analysis of the FLAVOUR randomized trial (Fractional Flow Reserve
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Clinical Benefit of Intravascular Imaging Compared With Conventional Angiography in Left Main Coronary Artery Intervention. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-29 Woochan Kwon,Joo Myung Lee,Kyeong Ho Yun,Ki Hong Choi,Seung-Jae Lee,Jong-Young Lee,Sang Yeub Lee,Sang Min Kim,Jae Young Cho,Chan Joon Kim,Hyo-Suk Ahn,Chang-Wook Nam,Hyuck-Jun Yoon,Yong Hwan Park,Wang Soo Lee,Jin-Ok Jeong,Pil Sang Song,Joon-Hyung Doh,Sang-Ho Jo,Chang-Hwan Yoon,Min Gyu Kang,Jin-Sin Koh,Kwan Yong Lee,Young-Hyo Lim,Yun-Hyeong Cho,Jin-Man Cho,Woo Jin Jang,Kook-Jin Chun,David Hong,Taek Kyu
BACKGROUND The RENOVATE-COMPLEX-PCI (Randomized Controlled Trial of Intravascular Imaging Guidance Versus Angiography-Guidance on Clinical Outcomes After Complex Percutaneous Coronary Intervention) demonstrated that intravascular imaging-guided percutaneous coronary intervention (PCI) improved clinical outcome compared with angiography-guided PCI for patients with complex coronary artery lesions. This
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Intravascular Imaging for Optimal Left Main Percutaneous Coronary Intervention: A Requirement Rather Than an Option. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-29 Debabrata Mukherjee
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Deferring PCI Based on IVUS Assessment: On Par With FFR or FLAVOUR of the Week? Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-29 Max W Maffey,Matthew A Cavender,Rodrigo Bagur
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Feasibility of Redo-Transcatheter Aortic Valve Replacement in Sapien Valves Based on In Vivo Computed Tomography Assessment. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 Miho Fukui,Atsushi Okada,Kiahltone R Thao,Marcus R Burns,Hideki Koike,Cheng Wang,Asa Phichaphop,John R Lesser,Paul Sorajja,João L Cavalcante,Vinayak N Bapat
BACKGROUND Our aim was to assess the feasibility of repeat transcatheter aortic valve (TAV) replacement for degenerated Sapien3 (S3) prostheses by simulating subsequent implantation of S3 or Evolut, using in vivo computed tomography-based sizing and the impact on coronary and patient-prosthesis mismatch risks. METHODS Computed tomography scans from 356 patients with prior S3 TAV replacement implantation
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Incorporating Redo-TAVR Feasibility Into Lifelong Aortic Valve Management. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 R Michael Reul,Alexander P Nissen,Stephanie K Tom,Elizabeth L Norton,Kendra J Grubb
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Feasibility of Coronary Access Following Redo-TAVR for Evolut Failure: A Computed Tomography Simulation Study. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 Gilbert H L Tang,Julianne Spencer,Toby Rogers,Kendra J Grubb,Patrick Gleason,Hemal Gada,Paul Mahoney,Harold L Dauerman,John K Forrest,Michael J Reardon,Philipp Blanke,Jonathon A Leipsic,Mohamed Abdel-Wahab,Guilherme F Attizzani,Rishi Puri,Michael Caskey,Christine J Chung,Ying-Hwa Chen,Dariusz Dudek,Keith B Allen,Adnan K Chhatriwalla,Wah Wah Htun,Daniel J Blackman,Giuseppe Tarantini,Jorge Zhingre Sanchez
BACKGROUND Coronary accessibility following redo-transcatheter aortic valve replacement (redo-TAVR) is increasingly important, particularly in younger low-risk patients. This study aimed to predict coronary accessibility after simulated Sapien-3 balloon-expandable valve implantation within an Evolut supra-annular, self-expanding valve using pre-TAVR computed tomography (CT) imaging. METHODS A total
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Challenges and Future Directions in Redo Aortic Valve Reintervention After Transcatheter Aortic Valve Replacement Failure. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 Syed Zaid,Vinayak N Bapat,Janarthanan Sathananthan,Uri Landes,Ole De Backer,Giuseppe Tarantini,Kendra J Grubb,Tsuyoshi Kaneko,Omar K Khalique,Hasan Jilaihawi,Miho Fukui,Mahesh Madhavan,Busra Cangut,Katherine Harrington,Vinod H Thourani,Raj R Makkar,Martin B Leon,Michael J Mack,Gilbert H L Tang
Transcatheter aortic valve replacement (TAVR) is increasingly being performed in younger and lower surgical risk patients. Reintervention for failed transcatheter heart valves will likely increase in the future as younger patients are expected to outlive the initial bioprosthesis. While redo-TAVR has emerged as an attractive and less invasive alternative to surgical explantation (TAVR-explant) to treat
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Valve-in-Valve Transcatheter Aortic Valve Replacement Following 2 Surgical Aortic Valve Replacements. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 Ghadi Moubarak,Swapnil Gupta,Jonathan Ladner,Austin Kluis,Jasjit Banwait,J Michael DiMaio,Michael J Mack,Molly I Szerlip
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Redo Transcatheter Aortic Valve Implantation in the Lotus Mechanically Expanded Transcatheter Heart Valve: Bench-Top Analysis, Clinical Experience, and Procedural Guidance. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 Mesfer Alfadhel,Chris Frawley,Janarthanan Sathananthan,Ole de Backer,Mohamed Abdel-Wahab,Ahmed Abdelhafez,Nicolas M Van Mieghem,Mark van den Dorpel,Sandeep Arunothayaraj,David Hildick-Smith,Daniel J Blackman
BACKGROUND Redo transcatheter aortic valve implantation (TAVI) is increasing as patients outlive their transcatheter heart valves (THVs) and present with bioprosthetic valve failure. The Lotus mechanically expanded THV has unique design characteristics, which have specific implications for Redo TAVI. METHODS The design features of the Lotus valve and their relevance to Redo TAVI were reviewed. Bench-top
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CT Simulation for Redo-TAVR: Can We Predict Future Coronary Access? Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-21 Zaid I Almarzooq,Pinak B Shah
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Efficacy and User Experience of a Novel X-Ray Shield on Operator Radiation Exposure During Cardiac Catheterization: A Randomized Controlled Trial. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-13 Cedric Davidsen,Kristian Ytre-Hauge,Andreas Tefre Samnøy,Kjell Vikenes,Patrizio Lancellotti,Vegard Tuseth
BACKGROUND Radiation shielding is mandatory during cardiac catheterization, but there is a need to improve efficacy and ease of use. METHODS The aim of the study was to assess the shielding effect and user feedback for a novel flexible multiconfiguration x-ray shield (FMX). The 0.5-mm Pb equivalent FMX can be selectively configured to accommodate for variations in patient morphology, access site, and
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Shielding for Radiation Safety in the Cardiac Catheterization Laboratory. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-13 Jay Khambhati,Jane A Leopold
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Expansion of Transcatheter Aortic Valve Implantation and Mortality due to Aortic Stenosis Between 2010 and 2019. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-09 Christoph Ryffel,Stephan Windecker,Thomas Pilgrim
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Cardiac Reverse Remodeling and Changes in Heart Failure Indices After Transcatheter Tricuspid Valve Replacement in Adults With Congenital Heart Disease. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-09 Abdalla A Salama,Omar A Abozied,Jason H Anderson,William R Miranda,Heidi M Connolly,Charles Jain,Allison Cabalka,Alexander C Egbe
BACKGROUND There are limited data about changes in cardiac function (cardiac reverse remodeling) and heart failure indices after transcatheter tricuspid valve-in-valve replacement (TT-VIVR). The purpose of this study was to evaluate cardiac reverse remodeling and temporal changes in heart failure indices after TT-VIVR in adults with congenital heart disease. METHODS Retrospective cohort study of adults
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Characterising Mechanisms of Ischemia in Patients with Myocardial Bridges. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-06 Aish Sinha,Haseeb Rahman,Ronak Rajani,Ozan Mehmet Demir,Matthew Emile Li Kam Wa,Holly Morgan,Saad M Ezad,Howard Ellis,Dexter Hogan,Ankur Gulati,Ajay M Shah,Amedeo Chiribiri,Andrew Webb,Michael Marber,Divaka Perera
Background: Myocardial bridges (MBs) are prevalent and can be associated with acute and chronic ischemic syndromes. We sought to determine the substrates for ischemia in patients with angina, nonobstructive coronary arteries (ANOCA) and a MB in the left anterior descending artery. Methods: Patients with ANOCA underwent acquisition of intracoronary pressure and flow during rest, supine bicycle exercise
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Angiographic Severity of the Non-culprit Lesion and the Efficacy of Fractional Flow Reserve-guided Complete Revascularization in AMI Patients: FRAMI-AMI Substudy. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-06 Jaeho Seung,Eun Ho Choo,Chan Joon Kim,Hyun Kuk Kim,Keun-Ho Park,Seung Hun Lee,Min Chul Kim,Young Joon Hong,Sung Gyun Ahn,Joon-Hyung Doh,Sang Yeub Lee,Sang-Don Park,Hyun Jong Lee,Min Gyu Kang,Jin-Sin Koh,Yun-Kyeong Cho,Chang-Wook Nam,Bon-Kwon Koo,Bong-Ki Lee,Kyeong Ho Yun,David Hong,Hyun Sung Joh,Ki Hong Choi,Taek Kyu Park,Joo Myung Lee,Jeong Hoon Yang,Young Bin Song,Seung-Hyuk Choi,Hyeon-Cheol Gwon
Background: The benefit of fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) for non-infarct related artery (IRA) lesions with angiographically severe stenosis in patients with acute myocardial infarction (MI) is unclear. Methods: Among 562 patients from FRAME-AMI trial who were randomly allocated into either FFR-guided or angiography-guided PCI for non-IRA lesions, the
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Navigating the Course of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: A Review of Guided Approaches. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-11-01 Nicola Ammirabile,Davide Landolina,Davide Capodanno
Dual antiplatelet therapy (DAPT) is the standard approach to prevent thrombotic events in patients undergoing percutaneous coronary intervention and presenting with chronic or acute coronary syndromes. However, a sizeable proportion of patients presents with an impaired or unwarranted response to DAPT depending on genetic polymorphisms or variability in platelet response. Therefore, the concept of
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Drug-Coated Balloon Angioplasty for De Novo Lesions on the Left Anterior Descending Artery. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-24 Mauro Gitto,Alessandro Sticchi,Mauro Chiarito,Laura Novelli,Pier Pasquale Leone,Gianluca Mincione,Angelo Oliva,Francesco Condello,Marco Luciano Rossi,Damiano Regazzoli,Gabriele Gasparini,Ottavia Cozzi,Giulio G Stefanini,Gianluigi Condorelli,Bernhard Reimers,Antonio Mangieri,Antonio Colombo
BACKGROUND Drug-coated balloons (DCB) are an emerging tool for modern percutaneous coronary intervention (PCI), but evidence on their use for de novo lesions on large vessels is limited. METHODS Consecutive patients undergoing DCB-based PCI on the left anterior descending artery in 2 Italian centers from 2018 to 2022 were retrospectively enrolled and compared with patients who received left anterior
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Association Between Polyvascular Disease and Transcatheter Aortic Valve Replacement Outcomes: Insights from the STS/ACC TVT Registry. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-23 Kannu Bansal,Aakriti Soni,Miloni Shah,Andrzej S Kosinski,Fahad Gilani,Sahil Khera,Sreekanth Vemulapalli,Sammy Elmariah,Dhaval Kolte
Background: Atherosclerotic cardiovascular disease (ASCVD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Polyvascular disease (PVD), defined as involvement of ≥2 vascular beds (VB) i.e., coronary, cerebrovascular, or peripheral, portends a poor prognosis in patients with ASCVD; however, data on the association of PVD with outcomes
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Massive Pulmonary Embolism: Optimizing Collaborative Care and Endovascular Therapy. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-17 Suresh Vedantham
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Impact of Calcium Eccentricity on the Safety and Effectiveness of Coronary Intravascular Lithotripsy: Pooled Analysis From the Disrupt CAD Studies. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-17 Ziad A Ali,Dean J Kereiakes,Jonathan M Hill,Shigeru Saito,Carlo Di Mario,Benjamin Honton,Nieves Gonzalo,Robert F Riley,Akiko Maehara,Mitsuaki Matsumura,Doosup Shin,Gregg W Stone,Richard A Shlofmitz
BACKGROUND Coronary intravascular lithotripsy (IVL) safely facilitates successful stent implantation in severely calcified lesions. This analysis sought to determine the relative impact of lesion calcium eccentricity on the safety and effectiveness of IVL using high-resolution optical coherence tomography imaging. METHODS Individual patient-level data (n=262) were pooled from 4 distinct international
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Outcomes in High-Risk Pulmonary Embolism Patients Undergoing FlowTriever Mechanical Thrombectomy or Other Contemporary Therapies: Results From the FLAME Study. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-17 Mitchell J Silver,C Michael Gibson,Jay Giri,Sameer Khandhar,Wissam Jaber,Catalin Toma,Bushra Mina,Terry Bowers,Lee Greenspon,Herman Kado,David M Zlotnick,Mithun Chakravarthy,Aaron R DuCoffe,Paul Butros,James M Horowitz
BACKGROUND Hemodynamically unstable high-risk, or massive, pulmonary embolism (PE) has a reported in-hospital mortality of over 25%. Systemic thrombolysis is the guideline-recommended treatment despite limited evidence. The FLAME study (FlowTriever for Acute Massive PE) was designed to generate evidence for interventional treatments in high-risk PE. METHODS The FLAME study was a prospective, multicenter
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Quantitative Flow Ratio Is Feasible and Accurate Even at Lower Frame Acquisition Rate. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-17 Andrea Milzi,Rosalia Dettori,Richard Karl Lubberich,Sebastian Reith,Kathrin Burgmaier,Nikolaus Marx,Mathias Burgmaier
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Outcomes Following Transcatheter Aortic Valve Replacement for Aortic Stenosis in Patients With Type 0 Bicuspid, Type 1 Bicuspid, and Tricuspid Aortic Valves. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-10-17 Jingjing He,Tian-Yuan Xiong,Yi-Jun Yao,Yong Peng,Jia-Fu Wei,Zhen-Gang Zhao,Guo Chen,Yuan-Weixiang Ou,Qi Liu,Xi Wang,Zhongkai Zhu,Hao-Ran Yang,Kaiyu Jia,Darren Mylotte,Nicolo Piazza,Bernard Prendergast,Yuan Feng,Mao Chen
BACKGROUND Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid aortic stenosis (AS) are scarce. The study aims to compare the outcomes of transcatheter aortic valve replacement for AS in patients with type 0 bicuspid, type 1 bicuspid, and tricuspid aortic valve anatomy. METHODS We enrolled consecutive patients undergoing transcatheter aortic valve replacement for
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Refractory Shockable Rhythms: The Exception That Proves the Rule After Out-of-Hospital Cardiac Arrest. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-26 Joshua C Reynolds
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First-in-Human Endovascular Aortic Root Repair (Endo-Bentall) for Acute Type A Dissection. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-22 Mehrdad Ghoreishi,Diljon Chahal,Aakash Shah,Jeanwan Kang,Jeffrey Hirsch,Douglas Tran,Dana McCloskey,Melsjan Shkullaku,Anuj Gupta,Erik R Strauss,Siamak Dahi,Bradley S Taylor,Shahab Toursavadkohi
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Hybrid Closure of Postinfarction Apical Ventricular Septal Defect Using Septal Occluder Device and Right Ventricular Free Wall: The Apical BASSINET Concept. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-21 Hiroki A Ueyama,Bradley G Leshnower,Errol K Inci,W Brent Keeling,Andy Tully,Robert A Guyton,Joe X Xie,Patrick T Gleason,Isida Byku,Chandan M Devireddy,George S Hanzel,Peter C Block,Robert J Lederman,Adam B Greenbaum,Vasilis C Babaliaros
BACKGROUND Postinfarction ventricular septal defect (VSD) is a catastrophic complication of myocardial infarction. Surgical repair still has poor outcomes. This report describes clinical outcomes after a novel hybrid transcatheter/surgical repair in patients with apical VSD. METHODS Seven patients with postmyocardial infarction apical VSD underwent hybrid transcatheter repair via subxiphoid surgical
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Complete Revascularization Versus Culprit-Lesion-Only PCI in STEMI Patients With Diabetes and Multivessel Coronary Artery Disease: Results From the COMPLETE Trial. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-19 Zardasht Oqab,Vijay Kunadian,David A Wood,Robert F Storey,Sunil V Rao,Roxana Mehran,Natalia Pinilla-Echeverri,Thenmozhi Mani,Robert H Boone,Saleem Kassam,Matthias Bossard,Samer Mansour,Warren Ball,Matthew Sibbald,Nicholas Valettas,Raul Moreno,Philippe Gabriel Steg,John A Cairns,Shamir R Mehta
BACKGROUND In the COMPLETE trial (Complete Versus Culprit-Only Revascularization to Treat Multivessel Disease After Early PCI for STEMI), a strategy of complete revascularization reduced the risk of major cardiovascular events compared with culprit-lesion-only percutaneous coronary intervention in patients presenting with ST-segment-elevation myocardial infarction (STEMI) and multivessel coronary artery
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Is COMPLETE Revascularization Beneficial in Diabetic Patients With Multivessel CAD Undergoing Primary PCI for STEMI? Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-19 Nicola Ryan,William F Fearon
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Adoption and Diffusion of Transcarotid Artery Revascularization in Contemporary Practice. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-19 Jesse A Columbo,David H Stone,Pablo Martinez-Camblor,Philip P Goodney,A James O'Malley
BACKGROUND In 2015, the FDA approved transcarotid artery revascularization (TCAR) as an alternative to carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TF-CAS) for high-risk patients with carotid stenosis. This was granted in the absence of level 1 evidence to support TCAR. We aimed to document trends in TCAR utilization, its diffusion over time, and the clinical phenotypes of
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Sex-Specific Differences in Potent P2Y12 Inhibitor Use in British Cardiovascular Intervention Society Registry STEMI Patients. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-19 Sonya N Burgess,Ahmad Shoaib,Andrew S P Sharp,Peter Ludman,Michelle M Graham,Gemma A Figtree,Evangelos Kontopantelis,Muhammad Rashid,Tim Kinnaird,Mamas A Mamas
BACKGROUND Sex-based outcome differences for women with ST-segment-elevation myocardial infarction (STEMI) have not been adequately addressed, and the role played by differences in prescription of potent P2Y12 inhibitors (P-P2Y12) is not well defined. This study explores the hypothesis that disparities in P-P2Y12 (prasugrel or ticagrelor) use may play a role in outcome disparities for women with STEMI
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Integrated Assessment of Computational Coronary Physiology From a Single Angiographic View in Patients Undergoing TAVI. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-15 Simone Fezzi,Daixin Ding,Roberto Scarsini,Jiayue Huang,Paolo Alberto Del Sole,Qiang Zhao,Gabriele Pesarini,Andrew Simpkin,William Wijns,Flavio Ribichini,Shengxian Tu
BACKGROUND Angiography-derived computational physiology is an appealing alternative to pressure-wire coronary physiology assessment. However, little is known about its reliability in the setting of severe aortic stenosis. This study sought to provide an integrated assessment of epicardial and microvascular coronary circulation by means of single-view angiography-derived physiology in patients with
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Septal Bipolar Ablation to Prevent Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Implantation. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-09-15 Michael H Hoskins,John C Lisko,Adam B Greenbaum,Hiroki A Ueyama,Faisal M Merchant,Michael S Lloyd,Patrick T Gleason,Mikhael F El-Chami,Isida Byku,Peter C Block,Robert J Lederman,Vasilis C Babaliaros,Stacy B Westerman
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Augmented Reality and Ultrasound-Guided Vascular Access. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-08-31 Abdullah Al-Abcha,Mohamad Alkhouli,Abhiram Prasad,Malcolm Bell,Suraj Yalamuri,Amir Lerman,Rajiv Gulati,Trevor Simard
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Short-Term DAPT and DAPT De-Escalation Strategies for Patients With Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-08-23 Toshiki Kuno,Atsuyuki Watanabe,Satoshi Shoji,Tomohiro Fujisaki,Hiroki Ueyama,Hisato Takagi,Pierre Deharo,Thomas Cuisset,Sripal Bangalore,Roxana Mehran,Gregg W Stone,Shun Kohsaka,Deepak L Bhatt
BACKGROUND Short-term (≤6 months) dual antiplatelet therapy (DAPT) and DAPT de-escalation become attractive for patients with acute coronary syndrome. METHODS A systemic search identified randomized controlled trials that included patients with acute coronary syndrome treated using (1) standard DAPT (12 months) with clopidogrel, prasugrel (standard/low dose), or ticagrelor; (2) extended DAPT (≥18 months);
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Unraveling the Maze of De-Escalation Strategies in Acute Coronary Syndromes. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-08-23 Davide Capodanno,Claudio Laudani
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Response by Yamamoto et al to Letter Regarding Article, "Target Lesion Revascularization After Intravascular Ultrasound-Guided Percutaneous Coronary Intervention". Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-08-23 Ko Yamamoto,Hiroki Shiomi,Takeshi Morimoto,Takeshi Kimura
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Letter by Garmendia and Garcia-Garcia Regarding Article, "Target Lesion Revascularization After Intravascular Ultrasound-Guided Percutaneous Coronary Intervention". Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-08-23 Cristian M Garmendia,Hector M Garcia-Garcia
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Hemodynamic Predictors of Outcome Following Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy. Circ. Cardiovasc. Interv. (IF 5.6) Pub Date : 2023-08-15 Mohamad S Alabdaljabar,Emily E Cendrowski,Rick A Nishimura,William R Miranda,Jeffrey B Geske,Charanjit S Rihal,Mackram F Eleid
BACKGROUND Alcohol septal ablation (ASA) is a minimally invasive treatment for drug-refractory obstructive hypertrophic cardiomyopathy. Detailed assessment of pressure changes and predictors of mortality and procedure success are not well defined. METHODS This is a single-center study evaluating pressure changes and predictors of mortality and procedure success in transseptal ASA. Survival analysis