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Global, regional, and national burden of blindness and vision loss attributable to high fasting plasma glucose from 1990 to 2019, and forecasts to 2030: A systematic analysis for the Global Burden of Disease Study 2019 Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-04-18 Cong Li, Guangyao Hua, Shunming Liu, Honghua Yu, Xiaohong Yang, Lei Liu
AimsTo systematically clarify the spatiotemporal trends, and age‐sex‐specific blindness and vision loss (BVL) burden due to high fasting plasma glucose (HFPG) from 1990 to 2019, and project this burden over the next decade.Materials and MethodsWe obtained the number and rate of years lived with disability (YLDs) for the BVL burden attributable to HFPG by age, sex, socio‐demographic index (SDI), and
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Multi‐feature, Chinese–Western medicine‐integrated prediction model for diabetic peripheral neuropathy based on machine learning and SHAP Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-04-15 Aijuan Jiang, Jiajie Li, Lujie Wang, Wenshu Zha, Yixuan Lin, Jindong Zhao, Zhaohui Fang, Guoming Shen
BackgroundClinical studies have shown that diabetic peripheral neuropathy (DPN) has been on the rise, with most patients presenting with severe and progressive symptoms. Currently, most of the available prediction models for DPN are derived from general clinical information and laboratory indicators. Several Traditional Chinese medicine (TCM) indicators have been utilised to construct prediction models
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The unique multidisciplinarity of diabetes‐related foot disease Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-04-15 Jaap J. van Netten, Jan Apelqvist, Sicco A. Bus, Robert Fitridge, Fran Game, Matilde Monteiro‐Soares, Eric Senneville, Nicolaas C. Schaper
Few diseases globally require treatment from so many different disciplines as diabetes‐related foot disease. At least 25 different professionals may be involved: casting technicians, dermatologists, diabetes (educator) nurses, diabetologists, dieticians, endocrinologists, general practitioners, human movement scientists, infectious diseases experts, microbiologists, nuclear medicine physicians, orthopaedic
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Associations of birth weight, plasma metabolome in adulthood and risk of type 2 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-04-06 Wenxiu Wang, Zhenhuang Zhuang, Yimin Zhao, Zimin Song, Ninghao Huang, Yueying Li, Xue Dong, Wendi Xiao, Tao Huang
AimsWe aimed to examine the longitudinal associations of birth weight with plasma metabolites in adulthood, and further quantify the proportions of the links between birth weight and incident adult type 2 diabetes (T2D) that were mediated by plasma metabolites.Materials and MethodsA total of 62,033 participants with complete nuclear magnetic resonance metabolomics and birth weight data from the UK
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LADA 30th anniversary: A growing form of diabetes with persistent unresolved questions Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-04-06 Ivy Lee Jia Jia, Raffaella Buzzetti, Richard David Leslie, Paolo Pozzilli
1 INTRODUCTION The 30th anniversary of Latent Autoimmune Diabetes in Adults (LADA) is a remarkable milestone in diabetes mellitus research. Described for the first time in 1993, LADA disputes the traditional binary classification of diabetes, with autoimmune features (autoimmune-mediated β-cell destruction) like that of type 1 diabetes (T1D) yet with an adult-onset pattern not requiring insulin, at
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Clusters of adipose tissue dysfunction in adults with type 2 diabetes identify those with worse lipidomic profile despite similar glycaemic control Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-04-01 Giuseppe Della Pepa, Fabrizia Carli, Silvia Sabatini, Samantha Pezzica, Marco Russo, Marilena Vitale, Maria Masulli, Gabriele Riccardi, Angela A. Rivellese, Olga Vaccaro, Lutgarda Bozzetto, Amalia Gastaldelli
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Adherence to GLP1‐RA and SGLT2‐I affects clinical outcomes and costs in patients with type 2 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-29 Stefano Ciardullo, Laura Savaré, Federico Rea, Gianluca Perseghin, Giovanni Corrao
AimsTo evaluate the impact of adherence to glucagon like peptide‐1 receptor agonists (GLP1‐RA) and sodium‐glucose transporter two inhibitors (SGLT2‐I) on clinical outcomes and costs in patients with type 2 diabetes mellitus (T2DM).Materials and MethodsThe 121,115 residents of the Lombardy Region (Italy) aged ≥40 years newly treated with metformin during 2007–2015 were followed to identify those who
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-28
No abstract is available for this article.
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Elevated liver enzymes in the first trimester are associated with gestational diabetes mellitus: A prospective cohort study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-28 Lingling Cui, Xiaoli Yang, Zhiqian Li, Yuting Gao, Zhengya Zhang, Dongmei Xu, Xinxin Liu
AimsPrevious studies have found that a single liver enzyme may predict gestational diabetes mellitus (GDM), but the results have been inconsistent. This study aimed to explore the associations of liver enzymes in early pregnancy with risk of GDM, as well as to independently rank risk factors.MethodsThis prospective cohort study included 1295 women who underwent liver enzyme measurements during early
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Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-28 Xiaoqin Xu, Jiang Li, Yuefeng Yu, Xiao Tan, Fei Xu, Bin Wang, Ningjian Wang, Yingli Lu
ObjectivePrediabetes and lifestyle factors have been associated with the risks of multiple adverse outcomes, but the effect of a healthy lifestyle on prediabetes‐related complications remains unknown. We aimed to investigate whether the risks of multiple adverse outcomes including incident type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), and chronic kidney disease (CKD) among individuals
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Overburden of rare ALMS1 deleterious variants in Chinese early‐onset type 2 diabetes with severe insulin resistance Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-28 Simin Zhang, Siqian Gong, Meng Li, Xiaoling Cai, Wei Liu, Yingying Lou, Yumin Ma, Xiuying Zhang, Qian Ren, Yu Zhu, Jing Wu, Lingli Zhou, Yufeng Li, Xianghai Zhou, Xueyao Han, Linong Ji
AimsAlström syndrome (AS) is a rare recessive disorder characterised by diabetes, obesity, insulin resistance (IR), and visual and hearing impairments. Mutations in the ALMS1 gene have been identified as the causative agents of AS. This study aimed to explore the relationship between rare ALMS1 variants and clinical features in Chinese patients with early‐onset type 2 diabetes (age at diagnosis ≤40
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Care, control and complications of hospitalised patients with type 1 diabetes in China: A nationwide-based registry study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-26 Chao Deng, Yuting Xie, Juan Li, Hongwei Jiang, Xiaohong Niu, Dewen Yan, Heng Su, Hongyu Kuang, Liming Tian, Jing Liu, Sheng Jiang, Huibiao Quan, Jixiong Xu, Xiaohong Wu, Na Tao, Shuguang Sun, Xiaohan Tang, Yan Chen, Li Fan, Xia Li, Zhiguang Zhou
To evaluate the status quo of type 1 diabetes (T1D) management and characteristics of hospitalised patients with T1D in China through a nationwide multicentre registry study, the China Diabetes Type 1 Study (CD1S).
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SGLT2 inhibition and three urological cancers: Up‐to‐date results Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-25 Lede Lin, Kang Ning, Liyuan Xiang, Liao Peng, Xiang Li
ObjectiveTo identify the causal role of sodium‐glucose cotransporter 2 (SGLT2) inhibition on three urological cancers.MethodsSix single nucleotide polymorphisms associated with the expression level of SLC5A2, a proxy for SGLT2 inhibition, from a recent publication were extracted. Three common urological cancers, including bladder cancer, prostate cancer and kidney cancer, were analysed. The main cohort
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Interaction effects of MTHFR C677T and A1298C polymorphisms with maternal glycated haemoglobin levels on adverse birth outcomes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-22 Weixiang Wu, Dan Luo, Cunwei Ji, Fuqiang Diao, Lihong Wu, Xiaolin Ruan, Chunming Gu, Mingyong Luo
AimsThe role of maternal genetic factors in the association between high glycated haemoglobin (HbA1c) levels and adverse birth outcomes remains unclear.Materials and MethodsIn this study, the maternal HbA1c levels of 5108 normoglycemic pregnant women in China were measured, and A1298C and C677T polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene were genotyped.ResultsElevated HbA1c
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Influence of sphingolipid enzymes on blood glucose levels, development of diabetes, and involvement of pericytes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-22 Karsten Buschard, Knud Josefsen, Lars Krogvold, Ivan Gerling, Knut Dahl‐Jørgensen, Flemming Pociot
AimsSulfatide is a chaperone for insulin manufacturing in beta cells. Here we explore whether the blood glucose values normally could be associated with this sphingolipid and especially two of its building enzymes CERS2 and CERS6. Both T1D and T2D have low blood sulfatide levels, and insulin resistance on beta cells at clinical diagnosis. Furthermore, we examined islet pericytes for sulfatide, and
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Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: A systematic review Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-20 Pam Chen, Nalini Campillo Vilorio, Ketan Dhatariya, William Jeffcoate, Ralf Lobmann, Caroline McIntosh, Alberto Piaggesi, John Steinberg, Prash Vas, Vijay Viswanathan, Stephanie Wu, Fran Game
BackgroundIt is critical that interventions used to enhance the healing of chronic foot ulcers in diabetes are backed by high‐quality evidence and cost‐effectiveness. In previous years, the systematic review accompanying guidelines published by the International Working Group of the Diabetic Foot performed 4‐yearly updates of previous searches, including trials of prospective, cross‐sectional and case‐control
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Erratum to Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-19
Serés-Noriega T, Viñals C, Perea V, et al. Adherence to an energy-restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes. Diabetes Metab Res Rev. 2024;e3783. https://doi.org/10.1002/dmrr.3783 In the previous version of the article, the term ‘children’ was used inadvertently instead of the term ‘subjects’ in some sections of
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Clinical metabolomics characteristics of diabetic kidney disease: A meta‐analysis of 1875 cases with diabetic kidney disease and 4503 controls Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-19 Yu Yuan, Liping Huang, Lulu Yu, Xingxu Yan, Siyu Chen, Chenghao Bi, Junjie He, Yiqing Zhao, Liu Yang, Li Ning, Hua Jin, Rongrong Yang, Yubo Li
AimsDiabetic Kidney Disease (DKD), one of the major complications of diabetes, is also a major cause of end‐stage renal disease. Metabolomics can provide a unique metabolic profile of the disease and thus predict or diagnose the development of the disease. Therefore, this study summarises a more comprehensive set of clinical biomarkers related to DKD to identify functional metabolites significantly
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Non‐invasive assessment of hepatic steatosis by ultrasound‐derived fat fraction in individuals at high‐risk for metabolic dysfunction‐associated steatotic liver disease Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-10 Federica Tavaglione, Valentina Flagiello, Francesca Terracciani, Paolo Gallo, Emma Capparelli, Chiara Spiezia, Antonio De Vincentis, Andrea Palermo, Sara Scriccia, Giovanni Galati, Nicola Napoli, Samuel J. Daniels, Jenny E. Blau, Björn Carlsson, Yeganeh M. Khazrai, Raffaele Antonelli Incalzi, Antonio Picardi, Umberto Vespasiani‐Gentilucci
AimsGiven the increasing number of individuals developing metabolic dysfunction‐associated steatotic liver disease (MASLD) and the low rate of those with progressive liver disease, there is a pressing need to conceive affordable biomarkers to assess MASLD in general population settings. Herein, we aimed to investigate the performance of the ultrasound‐derived fat fraction (UDFF) for hepatic steatosis
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Severe hypoglycemia and hypoglycemia awareness are associated with preclinical atherosclerosis in patients with type 1 diabetes without an estimated high cardiovascular risk Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-04 Alex Mesa, Marga Giménez, Verónica Perea, Tonet Serés‐Noriega, Laura Boswell, Jesús Blanco, Camila Milad, Adriana Pané, Enric Esmatjes, Irene Vinagre, Ignacio Conget, Clara Viñals, Antonio J. Amor
AimsTo explore the relationship between severe hypoglycemia (SH) and hypoglycemia awareness with preclinical atherosclerosis in type 1 diabetes (T1D).Materials and MethodsCross‐sectional study in patients with T1D without cardiovascular disease (CVD), and with ≥1 of the following: ≥40 years, diabetic kidney disease, or ≥10 years of T1D duration with another risk factor. CVD risk was estimated with
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Prevalence and risk factors of glomerular hyperfiltration in adults with type 2 diabetes: A population-based study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Domenico Tricò, Gian Paolo Fadini, Mario Luca Morieri, Riccardo Candido, Olga Eugenia Disoteo, Simona Frontoni, Anna Solini
Glomerular hyperfiltration characterises the earliest stage of diabetic nephropathy and predicts adverse kidney and cardiovascular outcomes. We aimed to assess the prevalence and risk factors of glomerular hyperfiltration in a population-based contemporary cohort of individuals with type 2 diabetes (T2D).
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Insulin requirements during pregnancy in women with type 1 diabetes treated with insulin pump Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-26 Nimrod Dori‐Dayan, Tali Cukierman‐Yaffe, Roni Zemet, Ohad Cohen, Keren Levi, Shali Mazaki‐Tovi, Rakefet Yoeli‐Ullman
IntroductionInsulin requirement in women with Type 1 diabetes (T1DM) changes throughout pregnancy. The aim of this study was to determine the total change in insulin requirements and the effect of gestational weight gain (GWG) and pre‐gestational BMI on insulin requirements during pregnancy in women with T1DM treated with continuous subcutaneous insulin infusion and continuous glucose monitoring.MethodsThis
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Diagnosis and treatment of diabetic foot ulcer complicated with lower extremity vasculopathy: Consensus recommendation from the Chinese Medical Association (CMA), Chinese Medical Doctor Association (CMDA) Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Kejia Wang, Yunchuan Wang, Wenlong Shi, Kuo Shen, Ke Tao, Rui Ling, Yuesheng Huang, Xiaobing Fu, Dahai Hu
Diabetic foot ulcer complicated with lower extremity vasculopathy is highly prevalent, slow healing and have a poor prognosis. The final progression leads to amputation, or may even be life‐threatening, seriously affecting patients' quality of life. The treatment of lower extremity vasculopathy is the focus of clinical practice and is vital to improving the healing process of diabetic foot ulcers.
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Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Tonet Serés‐Noriega, Clara Viñals, Verónica Perea, Alex Mesa, Laura Boswell, Karla Mariaca, Jesús Blanco, Irene Vinagre, Adriana Pané, Camila Milad, Clara Solà, Enric Esmatjes, Ignacio Conget, Marga Giménez, Antonio J. Amor
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Comparison between sodium‐glucose cotransporter 2 inhibitors and dipeptidyl peptidase 4 inhibitors on the risk of incident cancer in patients with diabetes mellitus: A real‐world evidence study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Hui‐Lin Sung, Chuan‐Yu Hung, Yu‐Chun Tung, Chih‐Chung Lin, Tung‐Han Tsai, Kuang‐Hua Huang
AimsSodium‐glucose cotransporter 2 inhibitors (SGLT‐2is) have been demonstrated to be associated with cancer cell mechanisms. However, whether they increase the risk of cancer remains unclear. Thus, this study aimed to determine the association between SGLT‐2i use and the incidence of cancer in patients with diabetes mellitus (DM) in Taiwan.Materials and MethodsThis retrospective cohort study was based
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-22
No abstract is available for this article.
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Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-20 A. Emile J. Hendriks, M. Loredana Marcovecchio, Rachel E. J. Besser, Ezio Bonifacio, Kristina Casteels, Helena Elding Larsson, Gita Gemulla, Markus Lundgren, Olga Kordonouri, Roberto Mallone, Flemming Pociot, Agnieszka Szypowska, Jorma Toppari, Thekla von dem Berge, Anette G. Ziegler, Chantal Mathieu, Peter Achenbach
Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta-cell antigens, preceding clinical diagnosis by a period of preclinical disease activity. As screening activity to identify autoantibody-positive individuals increases, a rise in presymptomatic type 1 diabetes individuals seeking medical attention is expected. Current guidance on how
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Time-dependent risk of fracture in adults with type 2 diabetes receiving anti-diabetic drug: A one-stage network meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-17 Yanjiao Shen, Qingyang Shi, Xinyu Zou, Wentong Meng, Haoming Tian, Liang Du, Sheyu Li
To assess the time-dependent risk of fracture in adults with type 2 diabetes receiving anti-diabetic drugs.
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Donor fat-to-muscle ratio and kidney transplant outcomes: A proposition of metabolic memory Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-17 Youn Kyung Kee, Juhan Lee, Bo Young Nam, Young Su Joo, Shin-Wook Kang, Kyu Ha Huh, Jung Tak Park
The impact of donor abdominal fat-to-muscle ratio (FMR) on kidney transplant (KT) outcomes was assessed. Given the transient nature of the donor's metabolic environment in transplant recipients, this study investigated the capacity of body composition to induce metabolic memory effects.
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Brain alterations in regions associated with end-organ diabetic microvascular disease in diabetes mellitus: A UK Biobank study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-16 Jamie Burgess, Christophe de Bezenac, Simon S. Keller, Bernhard Frank, Ioannis N. Petropoulos, Marta Garcia-Finana, Timothy L. Jackson, Varo Kirthi, Daniel J. Cuthbertson, Dinesh Selvarajah, Solomon Tesfaye, Uazman Alam
Diabetes mellitus (DM) is associated with structural grey matter alterations in the brain, including changes in the somatosensory and pain processing regions seen in association with diabetic peripheral neuropathy. In this case-controlled biobank study, we aimed to ascertain differences in grey and white matter anatomy in people with DM compared with non-diabetic controls (NDC).
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Chrononutrition in type 2 diabetes mellitus and obesity: A narrative review Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-16 Ludovica Verde, Tonia Di Lorenzo, Silvia Savastano, Annamaria Colao, Luigi Barrea, Giovanna Muscogiuri
Chrononutrition is a nutritional regimen that follows our biological clock, marked by the changes in metabolism that occur during the day. This regimen includes the distribution of energy, the regularity and frequency of meals, and the importance of these factors for metabolic health. A growing body of animal and human evidence indicates that the timing of food intake throughout the day can have a
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Chrononutrition in cardiometabolic diseases: Current evidence and future perspectives Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-13 Salvatore Carbone, Paolo Pozzilli
Chrononutrition is the field of nutritional science that investigates the relationship between food intake, timing of food intake, and their effects and influence on circadian rhythms and overall health. By aligning eating patterns with body's internal clock, optimisation of metabolic processes, improvements of various aspects of health can be achieved. Cardiovascular (CV) and metabolic diseases remain
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Metabolically healthy obesity, transition from metabolic healthy to unhealthy status, and carotid atherosclerosis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-13 Qin Huang, Zeyu Liu, Minping Wei, Jie Feng, Qing Huang, Yunhai Liu, Zunjing Liu, XiaoJun Li, Li Yin, Jian Xia
Evidence of the effects of metabolically healthy obesity (MHO) on atherosclerosis is limited; the transition effects of metabolic health and obesity phenotypes have been ignored. We examined the association between metabolic health and the transition to atherosclerosis risk across body mass index (BMI) categories in a community population.
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The impact of sodium-glucose co-transporter-2 inhibitors on dementia and cardiovascular events in diabetic patients with atrial fibrillation Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-10 Yun-Yu Chen, Hao-Chih Chang, Yenn-Jiang Lin, Kuo-Liong Chien, Yu-Cheng Hsieh, Fa-Po Chung, Ching-Heng Lin, Gregory Y. H. Lip, Shih-Ann Chen
The effectiveness of sodium-glucose co-transporter-2 inhibitors (SGLT2i) on incident dementia in patients with diabetes and atrial fibrillation (AF) remains unknown. This study aimed to investigate the association between SGLT2i and the risk of incident dementia in diabetic patients with AF, and to explore the interactions with oral anticoagulants or dipeptidyl peptidase-4 inhibitors (DPP4i).
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Plasma-derived exosomal miRNA profiles associated with type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-10 Haipeng Pang, Wenqi Fan, Linhua Pi, Xiajie Shi, Zhen Wang, Shuoming Luo, Yang Xiao, Xia Li, Gan Huang, Zhiguo Xie, Zhiguang Zhou
Recently, exosomal miRNAs have been shown to play important roles in multiple diseases, including type 1 diabetes (T1D). To assess the biomarker potential of exosomal miRNAs for T1D, we measured the expression profiles of plasma-derived exosomal miRNAs in T1D and explored their potential functions by bioinformatic analysis.
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Offloading and adherence through technological advancements: Modern approaches for better foot care in diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-08 Sicco A. Bus, Neil D. Reeves, David G. Armstrong, Bijan Najafi
This manuscript aims to provide a review and synthesis of contemporary advancements in footwear, sensor technology for remote monitoring, and digital health, with a focus on improving offloading and measuring and enhancing adherence to offloading in diabetic foot care.
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Association of sodium–glucose cotransporter-2 inhibitors and the risk of retinal vascular occlusion: A real-world retrospective cohort study in Taiwan Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-07 Tzu-Yi Lin, Eugene Yu-Chuan Kang, Shih-Chieh Shao, Edward Chia-Cheng Lai, Nan-Kai Wang, Sunir J. Garg, Kuan-Jen Chen, Je-Ho Kang, Wei-Chi Wu, Chi-Chun Lai, Yih-Shiou Hwang
Sodium–glucose cotransporter-2 inhibitors (SGLT2is) are proposed to alleviate the development of inflammatory eye diseases. However, the association between SGLT2i and retinal vascular occlusion remains unclear. Therefore, this study aims to explore the effects of SGLT2i on the incidence of retinal vascular occlusion.
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Type 1 diabetes: A new vision of the disease based on endotypes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-05 Craig Sinclair Weston, Bernhard O. Boehm, Paolo Pozzilli
Diagnosis and management of type 1 diabetes (T1D) have remained largely unchanged for the last several years. The management of the disease remains primarily focused on its phenotypical presentation and less on endotypes, namely the specific biological mechanisms behind the development of the disease. Furthermore, the treatment of T1D is essentially universal and indiscriminate—with patients administering
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Muscle-to-fat ratio in children and adolescents with type 1 diabetes in predicting glycaemic control and partial clinical remission Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-05 Shay Averbuch, Michal Yackobovitch-Gavan, Asaf Ben Simon, Hagar Interator, Adar Lopez, Ophir Borger, Irina Laurian, Anna Dorfman, Efrat Chorna, Asaf Oren, Ori Eyal, Avivit Brener, Yael Lebenthal
Advances in treatment could mitigate the expected adverse changes in the body composition of children and adolescents with type 1 diabetes (T1D).
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The transiency of metabolically healthy obesity: Metabolic decline and atherosclerotic risk Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-05 Saeid Mirzai, Ian J. Neeland, Carl J. Lavie
1 INTRODUCTION The concept of metabolically healthy obesity (MHO)—obesity in the absence of metabolic abnormalities such as hypertension, dyslipidemia, and hyperglycemia—has sparked intense debate.1 Up to 40% of people with obesity exhibit an MHO phenotype, seemingly escaping obesity's expected cardiometabolic sequelae.2 But is this a real phenomenon with a persistent favourable prognosis, or does
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Chronicles of progress: Celebrating 40 years of scientific excellence in diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-31 Paolo Pozzilli
The 40th anniversary of Diabetes Metabolism Research and Reviews (DMRR) marks a significant milestone in the field, reflecting four decades of continuous dedication to advancing our understanding of diabetes and related metabolic disorders. Over the years, the journal has been a pivotal platform for disseminating groundbreaking research and review articles that have shaped the landscape of diabetes
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-27
No abstract is available for this article.
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Assessment of six surrogate insulin resistance indexes for predicting cardiometabolic multimorbidity incidence in Chinese middle-aged and older populations: Insights from the China health and retirement longitudinal study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-24 Danrui Xiao, Honglin Sun, Long Chen, Xiang Li, Huanhuan Huo, Guo Zhou, Min Zhang, Ben He
Insulin resistance (IR) is associated with cardiometabolic multimorbidity (CMM). We aimed to explore the predictive value of six surrogate IR indexes—Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), triglyceride-glucose (TyG), atherogenic index of plasma (AIP), TyG-body mass index (TyGBMI), and TyG-waist circumference (TyGwaist)—to establish the CMM incidence in Chinese middle-aged
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The role of autophagy in insulin resistance and glucolipid metabolism and potential use of autophagy modulating natural products in the treatment of type 2 diabetes mellitus Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-24 Xiaoxue Yang, Wenwen Ding, Ziyi Chen, Kaiyi Lai, Ying Liu
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07
No abstract is available for this article.
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Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Deirdre K. Tobias, Rikuta Hamaya, Clary B. Clish, Liming Liang, Amy Deik, Courtney Dennis, Kevin Bullock, Cuilin Zhang, Frank B. Hu, JoAnn E. Manson
Several metabolites are individually related to incident type 2 diabetes (T2D) risk. We prospectively evaluated a novel T2D-metabolite pattern with a risk of progression to T2D among high-risk women with a history of gestational diabetes mellitus (GDM).
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Obesogenic environments as major determinants of a disease: It is time to re-shape our cities Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Ludovica Verde, Luigi Barrea, Jacqueline Bowman-Busato, Volkan Demirhan Yumuk, Annamaria Colao, Giovanna Muscogiuri
Obesity rates are increasing in almost all high- and low-income countries, and population-based approaches are necessary to reverse this trend. The current global efforts are focused on identifying the root causes of obesity and developing effective methods for early diagnosis, screening, treatment, and long-term management, both at an individual and health system level. However, there is a relative
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Poor self-rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Nadia Ramsingh, Hung-Mo Lin, Yuxia Ouyang, Ramit Ravona-Springer, Abigail Livny, Laili Soleimani, Barbara B. Bendlin, Mery Ben Meir, Anthony Heymann, Mary Sano, Joseph Azuri, Michal Schnaider Beeri
Self-rated health (SRH) is a predictor for poor health outcomes and cognition. Older adults with type 2 diabetes mellitus (T2D) have multi-morbidity and greater cognitive impairment. In the present study we investigated the association of SRH with cognitive decline and brain pathology in older adults with T2D.
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Chrono-nutrition for hypertension Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Natalie J. Bohmke, Dave L. Dixon, Danielle L. Kirkman
Despite the advancement in blood pressure (BP) lowering medications, uncontrolled hypertension persists, underscoring a stagnation of effective clinical strategies. Novel and effective lifestyle therapies are needed to prevent and manage hypertension to mitigate future progression to cardiovascular and chronic kidney diseases. Chrono-nutrition, aligning the timing of eating with environmental cues
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Cardio-renal-metabolic disease in primary care setting Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-19 Mahmoud Ibrahim, Ebtesam M. Ba-Essa, Jason Baker, Avivit Cahn, Antonio Ceriello, Francesco Cosentino, Melanie J. Davies, Robert H. Eckel, Luc Van Gaal, Peter Gaede, Yehuda Handelsman, Samuel Klein, Richard David Leslie, Paolo Pozzilli, Stefano Del Prato, Francesco Prattichizzo, Oliver Schnell, Petar M. Seferovic, Eberhard Standl, Abraham Thomas, Jaakko Tuomilehto, Paul Valensi, Guillermo E. Umpierrez
In the primary care setting providers have more tools available than ever before to impact positively obesity, diabetes, and their complications, such as renal and cardiac diseases. It is important to recognise what is available for treatment taking into account diabetes heterogeneity. For those who develop type 2 diabetes (T2DM), effective treatments are available that for the first time have shown
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Interactive effects of gestational diabetes and high pre-pregnancy body mass index on adverse growth patterns of offspring Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-18 Weihan Cao, Ninghua Li, Rui Zhang, Weiqin Li, Ming Gao, Hui Wang, Leishen Wang, Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang
To examine the independent and interactive effects of maternal gestational diabetes mellitus (GDM) and high pre-pregnancy body mass index (BMI) on the risk of offspring adverse growth patterns.
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Does a prior diagnosis of infectious disease confer an increased risk of latent autoimmune diabetes in adults? Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-16 Jessica Edstorp, Marios Rossides, Emma Ahlqvist, Bahareh Rasouli, Tiinamaija Tuomi, Sofia Carlsson
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Letter: Statin use in patients with type 2 diabetes has lower risk of hip fractures Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-13 Shih-Wei Huang, I.-Ming Jou, Renin Chang
We read with great interest the article ‘Statin use in patients with type 2 diabetes has lower risk of hip fractures: A Taiwan national population-based study’ by Tien-Ching Lee et al.1 They described that statin use was a significant and independent protective factor of hip fractures with an adjusted HR of 0.69. In addition, they noted a significant dose-response relationship between statin use and
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Longitudinal cardiovascular health measured by life's essential 8 metrics with incident diabetes: A 13-year prospective cohort study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-08 Xue Tian, Shuohua Chen, Qin Xu, Xue Xia, Yijun Zhang, Xiaoli Zhang, Penglian Wang, Shouling Wu, Anxin Wang
To investigate the associations of baseline and longitudinal cardiovascular health (CVH) measured by ‘Life's Essential 8’ (LE8) metrics with the risk of diabetes in Chinese people with normoglycaemia or prediabetes.
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Charcot neuroarthropathy in persons with diabetes: It's time for a paradigm shift in our thinking Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-08 Dane K. Wukich, Robert G. Frykberg, Venu Kavarthapu
The aim of this paper is to review the recent literature regarding the epidemiology and surgical management of Charcot neuro-osteoarthropathy (CNO). We propose that a fundamental change in the approach and assumptions regarding the historical treatment of active CNO should be considered. Although the true incidence and prevalence of CNO in the US population with diabetes are not known, we estimated
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Endostatin, soluble tumour necrosis factor receptor 1 and soluble tumour necrosis factor receptor 2 cannot predict new onset of microalbuminuria in patients with type 2 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-04 Florian G. Scurt, Jan Menne, Sabine Brandt, Anja Bernhardt, Peter R. Mertens, Hermann Haller, Christos Chatzikyrkou
Inflammation and angiogenesis play an important role in the development of early diabetic kidney disease. We investigated the association of soluble Tumour Necrosis Factor Receptor 1 (sTNF-R1), sTNF-R2 and endostatin with new onset microalbuminuria in normoalbuminuric patients with diabetes mellitus type 2.
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Incidence of type 1 diabetes mellitus in children and adolescents under 20 years of age across 55 countries from 2000 to 2022: A systematic review with meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-01 Ignacio Hormazábal-Aguayo, Yasmin Ezzatvar, Nidia Huerta-Uribe, Robinson Ramírez-Vélez, Mikel Izquierdo, Antonio García-Hermoso
The aim of this study was to determine the global incidence of type 1 diabetes mellitus (T1DM) in children and adolescents under 20 years of age from 2000 to 2022.
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The quest for wellness: How to optimise self-care strategies for diabetic foot management? Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-01 Frans Pouwer, Byron Perrin, Andy Lavender, Bijan Najafi, Khalida Ismail, Loretta Vileikyte
Diabetic foot ulceration (DFU) is common and highly recurrent, negatively impacting the individuals' quality of life. The 2023 guidelines of the International Working Group on the Diabetic Foot emphasise that adherence to foot self-care recommendations is one of the most important factors in DFU prevention. These guidelines also briefly mention that depression and other psychosocial problems can hamper
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Postbariatric surgery hypoglycemia: Nutritional, pharmacological and surgical perspectives Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-28 Giovanni Rossini, Renata Risi, Lavinia Monte, Biagio Sancetta, Maria Quadrini, Massimiliano Ugoccioni, Davide Masi, Rebecca Rossetti, Rossella D’Alessio, Rossella Mazzilli, Giuseppe Defeudis, Carla Lubrano, Lucio Gnessi, Mikiko Watanabe, Silvia Manfrini, Dario Tuccinardi
Post-bariatric hypoglycaemia (PBH) is a metabolic complication of bariatric surgery (BS), consisting of low post-prandial glucose levels in patients having undergone bariatric procedures. While BS is currently the most effective and relatively safe treatment for obesity and its complications, the development of PBH can significantly impact patients' quality of life and mental health. The diagnosis
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Efficacy and safety of fixed-ratio combination insulin degludec/liraglutide in type 2 diabetes: A systematic review and meta-analysis of randomised controlled trials Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-27 Rui Wang, Shuoming Luo, Zilin Xiao, Zhiguang Zhou
The efficacy and safety of fixed-ratio combination insulin degludec/liraglutide (IDegLira) for type 2 diabetes (T2DM) were extensively investigated by the global DUAL trials. However, the evidence on its efficacy and safety in T2DM has not been systematically reviewed.