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HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35 Horm. Cancer (IF 3.0) Pub Date : 2024-04-20 Yuting Ding, Wenkang Luan, Zhe Wang, Bo Xie, Chengfa Sun
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SLC35A2 expression is associated with HER2 expression in breast cancer Horm. Cancer (IF 3.0) Pub Date : 2024-04-19 Yiran Wang, Xiaobo Peng, Meihong Wu, Bin Wang, Tianran Chen, Xianbao Zhan
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The clinical significance and oncogenic function of LRRFIP1 in pancreatic cancer Horm. Cancer (IF 3.0) Pub Date : 2024-04-18 Jinping Li, Dayun Tuo, Gunan Guo, Yan Gao, Jinfeng Gan
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Prediction of prostate cancer aggressiveness using magnetic resonance imaging radiomics: a dual-center study Horm. Cancer (IF 3.0) Pub Date : 2024-04-16 Nini Pan, Liuyan Shi, Diliang He, Jianxin Zhao, Lianqiu Xiong, Lili Ma, Jing Li, Kai Ai, Lianping Zhao, Gang Huang
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T cell-mediated tumor killing sensitivity gene signature-based prognostic score for acute myeloid leukemia Horm. Cancer (IF 3.0) Pub Date : 2024-04-15 Yiyun Pan, FangFang Xie, Wen Zeng, Hailong Chen, Zhengcong Chen, Dechang Xu, Yijian Chen
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Circular RNA COL1A1 promotes Warburg effect and tumor growth in nasopharyngeal carcinoma Horm. Cancer (IF 3.0) Pub Date : 2024-04-15 ZeJun Zhou, Fang Xu, Tao Zhang
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Immune-related LncRNAs scores predicts chemotherapeutic responses and prognosis in cervical cancer patients Horm. Cancer (IF 3.0) Pub Date : 2024-04-14 Weijie Tian, Songsong Tan, Jun Wang, Ping Shen, Qingfen Qin, Dan Zi
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Application value of intraoperative electrophysiological monitoring in cerebral eloquent area glioma surgery: a retrospective cohort study Horm. Cancer (IF 3.0) Pub Date : 2024-04-13 Yuankun Liu, Songyun Zhao, Jin Huang, Pengpeng Zhang, Qi Wang, Zhuwen Chen, Lingjie Zhu, Wei Ji, Chao Cheng
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Identification of hub genes and diagnostic efficacy for triple-negative breast cancer through WGCNA and Mendelian randomization Horm. Cancer (IF 3.0) Pub Date : 2024-04-12 Yilong Lin, Songsong Wang, Qingmo Yang
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A combination of cuproptosis and lncRNAs predicts the prognosis and tumor immune microenvironment in cervical cancer Horm. Cancer (IF 3.0) Pub Date : 2024-04-12 Yitong Huang, Chenxiang Pan, Suni Wu, Feng Ye, Lihua Yang
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Bilateral adrenal neuroblastoma: peculiar pattern of a rare pediatric presentation Horm. Cancer (IF 3.0) Pub Date : 2024-04-12 Mohamed Fawzy, Gehad Ahmed, Yasser Youssef, Naglaa Elkinaai, Amal Refaat, Mai Amr Elahmadawy, Fadwa Said, Salma Elmenawi
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Diagnostic value of circulating tumor cells in patients with thyroid cancer: a retrospective study of 1478 patients Horm. Cancer (IF 3.0) Pub Date : 2024-04-12 Qingxin Zeng, Haifeng Zhong, Hui Rao, Yuedong Wang
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Advances in tumor microenvironment and underlying molecular mechanisms of bladder cancer: a systematic review Horm. Cancer (IF 3.0) Pub Date : 2024-04-11 Liu Tang, Haifei Xu, Tong Wu, Wenhao Wu, Yuhao Lu, Jijia Gu, Xiaoling Wang, Mei Zhou, Qiuyang Chen, Xuan Sun, Hongzhou Cai
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Integrating iron metabolism-related gene signature to evaluate prognosis and immune infiltration in nasopharyngeal carcinoma Horm. Cancer (IF 3.0) Pub Date : 2024-04-11 Jiaming Su, Guanlin Zhong, Weiling Qin, Lu Zhou, Jiemei Ye, Yinxing Ye, Chang Chen, Pan Liang, Weilin Zhao, Xue Xiao, Wensheng Wen, Wenqi Luo, Xiaoying Zhou, Zhe Zhang, Yonglin Cai, Cheng Li
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DSCAM-AS1 promotes the development of prostate cancer Horm. Cancer (IF 3.0) Pub Date : 2024-04-11 Lin Cheng, Shuhui Li, Deqi Jiang, Jianchao Zhang
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Hypoxic microenvironment-induced exosomes confer temozolomide resistance in glioma through transfer of pyruvate kinase M2 Horm. Cancer (IF 3.0) Pub Date : 2024-04-10 Guofu Li, Ziyu Xiong, Ying Li, Cong Yan, Yingying Cheng, Yuwen Wang, Jingwei Li, Zifeng Dai, Dongdong Zhang, Wenzhong Du, Chunyang Men, Changbin Shi
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L-cysteine contributes to destructive activities of odontogenic cysts/tumor Horm. Cancer (IF 3.0) Pub Date : 2024-04-08 Ji Li, Chunyu Feng, Xiaochan Pang, Xiang Li, Xinyu Dou, Erhui Jiang, Zhengjun Shang
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Significance and implications of FHIT gene expression and promoter hypermethylation in acute lymphoblastic leukemia (ALL) Horm. Cancer (IF 3.0) Pub Date : 2024-04-08 Fozia Mohammad, Arshad A. Pandith, Shayaq Ul Abeer Rasool, Faisal R. Guru, Iqbal Qasim, Sajad Geelani, Syed Nisar, Shahid M. Baba, Farooq A. Ganie, Safiya Kouser, Javid Rasool
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Relationship of mTORC1 and ferroptosis in tumors Horm. Cancer (IF 3.0) Pub Date : 2024-04-07 Huilin Liao, Yueqing Wang, Lili Zou, Yanmei Fan, Xinyue Wang, Xiancong Tu, Qiaobai Zhu, Jun Wang, Xiaowen Liu, Chuanjiang Dong
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Morbidity and mortality of patients with peritoneal malignancy following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy Horm. Cancer (IF 3.0) Pub Date : 2024-04-05 Greta Hotza, Michael Karageorgos, Varvara Pastourmatzi, Nader Baniowda, Dimitrios Kyziridis, Apostolos Kalakonas, Nicolaos Chavouzis, Irene Hotza, Antonios-Apostolos Tentes
Abstract Background The purpose of this study was to record the incidence, and identify the prognostic variables of morbidity and mortality in patients with peritoneal malignancy undergoing cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). Methods The files of patients with peritoneal malignancy who underwent CRS + HIPEC from 2015–2022 were retrieved. Morbidity
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BRD4 inhibitors broadly promote erastin-induced ferroptosis in different cell lines by targeting ROS and FSP1 Horm. Cancer (IF 3.0) Pub Date : 2024-04-03 Chenyang Fan, Xiaohong Guo, Jie Zhang, Wen Zheng, Chonglin Shi, Yongwei Qin, Haoliang Shen, Yang Lu, Yihui Fan, Yanli Li, Liuting Chen, Renfang Mao
Ferroptosis, an iron-dependent form of programmed cell death, is a promising strategy for cancer treatment. Bromodomain-containing protein 4 (BRD4) is an epigenetic reader and a promising target for cancer therapeutics. However, the role of BRD4 in ferroptosis is controversial and the value of the interaction between BRD4 inhibitors and ferroptosis inducers remains to be explored. Here, we found that
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MAP3K4 kinase action and dual role in cancer Horm. Cancer (IF 3.0) Pub Date : 2024-04-03 Yuxin Huang, Guanwen Wang, Ningning Zhang, Xiaohua Zeng
It is commonly known that the MAPK pathway is involved in translating environmental inputs, regulating downstream reactions, and maintaining the intrinsic dynamic balance. Numerous essential elements and regulatory processes are included in this pathway, which are essential to its functionality. Among these, MAP3K4, a member of the serine/threonine kinases family, plays vital roles throughout the organism's
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Development of chitosan-folate modified PLGA nanoparticles for targeted delivery of diosgenin as an anticancer agent Horm. Cancer (IF 3.0) Pub Date : 2024-04-03 Fatemeh Teymouri, Ehsan Karimi
Diosgenin as a potential phytoconstituent and steroidal saponin manifested significant anticancer agents against various cancers. To enhance its solubility and bioavailability in cancer treatment, we loaded diosgenin (PubChem CID: 99474) in poly(lactic-co-glycolide) (PLGA) nanoparticle coated with folic acid-chitosan (Da-PFC-NPs). The diosgenin nano-formulation was characterized and its antioxidant
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Cyclovirobuxine D inhibits hepatocellular carcinoma growth by inducing ferroptosis of hepatocellular carcinoma cells Horm. Cancer (IF 3.0) Pub Date : 2024-04-02 Xinru Jiang, Hongdan Li, Yang Liu
Objective Hepatocellular carcinoma (HCC) is one cancer with high death rates. Nowadays, there are no effective drugs to treat it. Cyclovirobuxine D (CVB-D) is the primary ingredient of the traditional Chinese medicine (TCM) Buxus microphylla. Here, we try to explore the impacts of CVB-D on human HCC cells and explain the potential mechanisms. Methods HepG2 and Huh-7 cells were used for our experiments
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Immunohistochemical and molecular profiles of heterogeneous components of metaplastic breast cancer: a squamous cell carcinomatous component was distinct from a spindle cell carcinomatous component Horm. Cancer (IF 3.0) Pub Date : 2024-04-02 Takahiro Suzuki, Yoko Nakanishi, Tomoyuki Tanino, Haruna Nishimaki-Watanabe, Hiroko Kobayashi, Sumie Ohni, Xiaoyan Tang, Kenichi Hakamada, Shinobu Masuda
Metaplastic breast carcinoma (MBC), a category of breast cancer, includes different histological types, which are occasionally mixed and heterogeneous. Considering the heterogeneity of cancer cells in a tumour mass has become highly significant, not only from a biological aspect but also for clinical management of recurrence. This study aimed to analyse the immunohistochemical and molecular profiles
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The combined effect of MTHFR C677T and A1298C polymorphisms on the risk of digestive system cancer among a hypertensive population Horm. Cancer (IF 3.0) Pub Date : 2024-04-02 Qiangqiang He, Yaping Wei, Hehao Zhu, Qiongyue Liang, Ping Chen, Shuqun Li, Yun Song, Lishun Liu, Binyan Wang, Xiping Xu, Yuhan Dong
Background and purpose The enzyme methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in directing folate species towards nucleotide synthesis or DNA methylation. The MTHFR polymorphisms C677T and A1298C have been linked to cancer susceptibility, but the evidence supporting this association has been equivocal. To investigate the individual and joint associations between MTHFR C677T, A1298C
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High-throughput metabolomics identifies new biomarkers for cervical cancer Horm. Cancer (IF 3.0) Pub Date : 2024-03-29 Xue Li, Liyi Zhang, Xuan Huang, Qi Peng, Shoutao Zhang, Jiangming Tang, Jing Wang, Dingqing Gui, Fanxin Zeng
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Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib Horm. Cancer (IF 3.0) Pub Date : 2024-03-28 Yi Zong, Zhigang Tao, Siyi Jiang, Minyuan Wang, Weihua Yu
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Nephroblastoma-specific dysregulated gene SNHG15 with prognostic significance: scRNA-Seq with bulk RNA-Seq data and experimental validation Horm. Cancer (IF 3.0) Pub Date : 2024-03-25 Mengmeng Chang, Ding Li, Li Su, Chen Ding, Zhiyi Lu, Hongjie Gao, Fengyin Sun
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Effect of Annexin A2 on prognosis and sensitivity to immune checkpoint plus tyrosine kinase inhibition in metastatic renal cell carcinoma Horm. Cancer (IF 3.0) Pub Date : 2024-03-22 Jiajun Wang, Jinglai Lin, Jiahao Wang, Ying Wang, Yanjun Zhu, Xianglai Xu, Jianming Guo
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Effect of early peri-operative arterial lactate concentration level ratios on post-hepatectomy liver failure Horm. Cancer (IF 3.0) Pub Date : 2024-03-21 Dong-Dong Wang, Meng-Meng Dong, Ya-Ming Xie, Fei-Qi Xu, Tian-Wei Fu, Yu-Chen Wu, Zhe Zhang, Yi Lu, Lei Liang, Wei-Feng Yao, Guo-Liang Shen, Jun-Wei Liu, Cheng-Wu Zhang, Qiu-Ran Xu, Zun-Qiang Xiao
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Genetically driven predisposition leads to an unusually genomic unstable renal cell carcinoma Horm. Cancer (IF 3.0) Pub Date : 2024-03-21 Manuel Scimeca, Valentina Rovella, Sabrina Caporali, Yufang Shi, Julia Bischof, Jonathan Woodsmith, Giuseppe Tisone, Giuseppe Sica, Ivano Amelio, Gerry Melino, Alessandro Mauriello, Pierluigi Bove
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Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma Horm. Cancer (IF 3.0) Pub Date : 2024-03-19 Mo Zhou, Yan Chen, Yanlei Gong, Mingqing Zhu, Jiannong Cen, Jinlan Pan, Lingzhi Yan, Jingjing Shang, Song Jin, Xiaolan Shi, Weiqin Yao, Shuang Yan, Depei Wu, Suning Chen, Chengcheng Fu, Li Yao
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Notch appearance as a novel radiological predictor of transient expansion and good outcome of expanding schwannoma after radiotherapy Horm. Cancer (IF 3.0) Pub Date : 2024-03-19 Masahiro Yamazaki, Shigeyuki Takamatsu, Yuta Iwata, Takayuki Sakurai, Masashi Taka, Satoshi Kobayashi, Toshifumi Gabata, Eiichi Mizuno
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Solid pseudopapillary neoplasm (SPN) of the pancreas: current understanding on its malignant potential and management Horm. Cancer (IF 3.0) Pub Date : 2024-03-18 Xiaoyue Lu, Hao Chen, Taiping Zhang
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Excluding external iliac node irradiation during neoadjuvant radiotherapy decreases lower intestinal toxicity without compromising efficacy in T4b rectal cancer patients with tumours involving the anterior structures Horm. Cancer (IF 3.0) Pub Date : 2024-03-16 Anchuan Li, Miaobin Mao, Runfan Chen, Pan Chi, Ying Huang, Junxin Wu, Benhua Xu
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GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation Horm. Cancer (IF 3.0) Pub Date : 2024-03-13 Haisheng Yi, Lingyun Liu, Jingshun Zhang, Kaimin Guo, Yin Cao, Penghao Sun, Hongliang Wang
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Role of long non-coding RNA ELFN1-AS1 in carcinogenesis Horm. Cancer (IF 3.0) Pub Date : 2024-03-13 Zanyar HajiEsmailpoor, Alireza Fayazi, Mohammadhossein Teymouri, Peyman Tabnak
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GABPB1 plays a cancer-promoting role in non-small cell lung cancer Horm. Cancer (IF 3.0) Pub Date : 2024-03-11 Tuo Wang, Cong Cao, Yu Fan, Jialing Xu, Tao Hua, Jie Ding, Zejie Liu, Beili Wang, Juanwen Lian
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A programmed cell death-related gene signature to predict prognosis and therapeutic responses in liver hepatocellular carcinoma Horm. Cancer (IF 3.0) Pub Date : 2024-03-11 Xinyu Gu, Jie Pan, Yanle Li, Liushun Feng
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Transcriptome and single-cell transcriptomics reveal prognostic value and potential mechanism of anoikis in skin cutaneous melanoma Horm. Cancer (IF 3.0) Pub Date : 2024-03-09 Xing Liu, Hong-Yan Zhang, Hong-Ao Deng
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Transarterial chemoembolization with/without immune checkpoint inhibitors plus tyrosine kinase inhibitors for unresectable hepatocellular carcinoma: a single center, propensity score matching real-world study Horm. Cancer (IF 3.0) Pub Date : 2024-03-09 Guosheng Yuan, Wenli Li, Mengya Zang, Rong Li, Qi Li, Xiaoyun Hu, Qi Zhang, Wei Huang, Jian Ruan, Huajin Pang, Jinzhang Chen
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DDOST is associated with tumor immunosuppressive microenvironment in cervical cancer Horm. Cancer (IF 3.0) Pub Date : 2024-03-09 Jie Mei, Liuliu Pan, Min Huang, Dandan Bao, Hui Gao, Danhan Wang
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Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma Horm. Cancer (IF 3.0) Pub Date : 2024-03-01 Li Mu, Shun Hu, Guoping Li, Ping Wu, Ke Zheng, Sheng Zhang
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The impact of different clinicopathologic factors and salvage therapies on cervical cancer patients with isolated para-aortic lymph node recurrence Horm. Cancer (IF 3.0) Pub Date : 2024-03-01 Chenyan Fang, Yinfeng Zhu, Ping Zhang, Tao Zhu, Yingli Zhang
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Current and future of immunotherapy for thyroid cancer based on bibliometrics and clinical trials Horm. Cancer (IF 3.0) Pub Date : 2024-02-25 Ke Wang, Ying Zhang, Yang Xing, Hong Wang, Minghua He, Rui Guo
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Visual conservation treatment dilemmas in neuroblastoma with bilateral blindness Horm. Cancer (IF 3.0) Pub Date : 2024-02-25 Haiyan Cheng, Yu Lin, Wei Yang, Xiaofeng Chang, Jun Feng, Shen Yang, Shan Liu, Tong Yu, Xiaojiao Peng, Panpan Zheng, Chengyue Zhang, Haiwei Jia, Hong Qin, Huanmin Wang
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Prognostic significance of LINC01132 in lung cancer and its regulatory role in tumor progression Horm. Cancer (IF 3.0) Pub Date : 2024-02-25 Yang Hu, Youying Wei
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Comprehensive pan-carcinoma analysis of ITGB1 distortion and its potential clinical significance for cancer immunity Horm. Cancer (IF 3.0) Pub Date : 2024-02-24 Yuchang Fei, Yulun Wu, Luting Chen, Huan Yu, Lei Pan
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Concomitant double-fusion of PLEKHA7-ALK and INPP5D-ALK reveals favorable alectinib sensitivity in lung adenocarcinoma: a case report and literature review Horm. Cancer (IF 3.0) Pub Date : 2024-02-20
Abstract Anaplastic lymphoma kinase (ALK) gene fusion is a classic driver mutation in non-small cell lung cancer (NSCLC); however, ALK double-fusion variants in NSCLC have rarely been reported. In this study, we reported a case with extremely uncommon ALK double-fusion variants. A 32-year-old female diagnosed with lung adenocarcinoma, who had developed multiple intrapulmonary and brain metastases,
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Identifying the tumor immune microenvironment-associated prognostic genes for prostate cancer Horm. Cancer (IF 3.0) Pub Date : 2024-02-20 Shi Zong, Ji Gao
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Feasibility analysis of arterial CT radiomics model to predict the risk of local and metastatic recurrence after radical cystectomy for bladder cancer Horm. Cancer (IF 3.0) Pub Date : 2024-02-19 Huawang Lv, Xiaozhou Zhou, Yuan Liu, Yuting Liu, Zhiwen Chen
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Delineating the role of nuclear receptors in colorectal cancer, a focused review Horm. Cancer (IF 3.0) Pub Date : 2024-02-19
Abstract Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally, causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to GLOBOCAN 2020, CRC ranks third in incidence and second in mortality in both males and females. Despite extensive studies over the years, there is still a need to establish novel therapeutic targets to enhance the
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Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study Horm. Cancer (IF 3.0) Pub Date : 2024-02-18 Samwel Rema Gesaka, Parmenas Minda Okemwa, Philip Maseghe Mwachaka
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Real-world prognostic significance of attaining minimal residual disease negativity in newly diagnosed multiple myeloma Horm. Cancer (IF 3.0) Pub Date : 2024-02-17 Jing Wang, Jing Li, Run Zhang, Jianyong Li, Lijuan Chen, Yuanyuan Jin
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The endoplasmic reticulum stress-related genes and molecular typing predicts prognosis and reveals characterization of tumor immune microenvironment in lung squamous cell carcinoma Horm. Cancer (IF 3.0) Pub Date : 2024-02-16 Ruolan Wang, Yanhua Huang, Juan He, Shan Jin, Xin Li, Kun Tan, Wei Xia
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Analysis of factors related to osteoporotic vertebral fracture in prostate cancer patients Horm. Cancer (IF 3.0) Pub Date : 2024-02-13 Shunfa Huang, Lilan Wu, Shuting Lin, Siqing Cai, Jianjun Zhou
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Research progress of exosomes in the angiogenesis of digestive system tumour Horm. Cancer (IF 3.0) Pub Date : 2024-02-11 Yuan Liu, Hao Wu, Yaodong Sang, Wei Chong, Liang Shang, Leping Li
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Hypofractionated versus conventional fractionation external beam radiotherapy in intermediate and high risk localized prostate cancer Horm. Cancer (IF 3.0) Pub Date : 2024-02-02 Eileen Samuel, Saliha Zaman, Muhammad Abu Bakar, Muhammad Mohsin Fareed
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PLCD3 inhibits apoptosis and promotes proliferation, invasion and migration in gastric cancer Horm. Cancer (IF 3.0) Pub Date : 2024-02-02 Yantao Yu, Shantanu Baral, Qiannan Sun, Jianyue Ding, Qi Zhang, Fanyu Zhao, Shuyang Gao, Qing Yao, Haoyue Yu, Bin Liu, Daorong Wang