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Accessory Right Hepatic Artery Pseudoaneurysm Resulting in Biliary Obstruction. Case Rep. Gastroenterol. Pub Date : 2023-11-28 Colin William Primrose,Nikolas Arestis
Introduction Visceral pseudoaneurysms are prone to rupture and can cause mass effect on surrounding structures, with extrinsic compression on the biliary tree being a rare but challenging complication. Case Presentation We report a case of a 48-year-old man with a history of alcohol excess who presented acutely unwell with jaundice. Imaging revealed a pseudoaneurysm of the accessory right hepatic artery
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Endoscopic Treatment of Colo-Colonic Intussusception in a Patient with Peutz-Jeghers Syndrome. Case Rep. Gastroenterol. Pub Date : 2023-11-17 Takeshi Fujima,Daisuke Saito,Hidenori Shibuta,Ryota Ogihara,Hiromu Morikubo,Ryo Ozaki,Sotaro Tokunaga,Shintaro Minowa,Tatsuya Mitsui,Miki Miura,Mari Hayashida,Yoshiko Watanabe,Jun Miyoshi,Minoru Matsuura,Junji Shibahara,Etsuji Ukiyama,Tadakazu Hisamatsu
A 19-year-old man with a history of Peutz-Jeghers syndrome (PJS) and two previous partial small bowel resections because of intussusception presented with lower abdominal pain. Computed tomography (CT) showed concentric multilayer and cord-like structures in the transverse colon. Colo-colonic intussusception was suspected and he was hospitalized. After two therapeutic enemas were unsuccessful, a colonoscopy
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Large Cell Neuroendocrine Carcinoma of the Gallbladder: Where Survival Is a Rare Entity - Case Report and Review of the Literature. Case Rep. Gastroenterol. Pub Date : 2023-11-16 Samyak Dhruv,Kuldeepsinh P Atodaria,Indraneil Mukherjee,Anil Kankaria,Umed K Shah
Introduction Carcinoma of the gallbladder is extremely rare, papillary adenocarcinoma comprises 90% of these cases. Although neuroendocrine neoplasms (NENs) comprise 0.5% of the cases of gallbladder cancer, the incidence is rising. NEN is classified into a well-differentiated neuroendocrine tumor and poorly differentiated neuroendocrine cancer (NEC). Histologically, NEC is small-cell or large-cell
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A Case of Gastric Perforation Caused by Excessive Insufflation during Upper Gastrointestinal Endoscopy: Nonoperative Management. Case Rep. Gastroenterol. Pub Date : 2023-11-15 Youn Su Park
Introduction Upper gastrointestinal endoscopy is used to diagnose and treat upper gastrointestinal diseases, but it can also cause complications, including perforation. Perforation is a serious complication, so it is important to be aware of the risk factors in advance and to take precautions to prevent it. Case Presentation We report a case of gastric perforation caused by excessive insufflation during
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Successful Endoscopic Removal of Anisakis Larva that Deeply Invaded the Gastric Mucosa Using Jumbo Forceps. Case Rep. Gastroenterol. Pub Date : 2023-11-08 Toshio Arai,Takehito Kunogi,Takahiro Kinebuchi,Yasuhiro Nakano,Koji Nishikawa,Hiromu Sugiyama
Anisakiasis is a parasitic disease caused by the ingestion of raw or uncooked seafood infected with third-stage larvae of anisakid nematodes. Generally, the larvae parasites live at the surface of the mucosa, but in this case, the larva deeply invaded its head into the gastric mucosa and was not removable with conventional biopsy forceps. In our case, we demonstrated the usefulness of jumbo forceps
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Secondary Colo-Colic Intussusception Caused by Giant Polyp of Sigmoid Colon in a 5-Year-Old Girl. Case Rep. Gastroenterol. Pub Date : 2023-11-08 Tan Haizhi,Xiao Xiaobing,Deng Jianrong
Intussusception is common in infants and young children. The most common type is small intestinal intussusception or ileo-colic intussusception. Colonic intussusception is rare. Intestinal polyps, especially large polyps or multiple polyps, can cause intussusception. Here, we report a rare case of colo-colic intussusception caused by a giant juvenile polyp of sigmoid colon, and the patient achieved
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An Autopsy Case of Ruptured Hepatic Angiosarcoma Treated by Transcatheter Arterial Embolization. Case Rep. Gastroenterol. Pub Date : 2023-10-16 Toshiki Entani,Kazuto Tajiri,Akira Noguchi,Aiko Murayama,Nozomu Muraishi,Yuka Hayashi,Ichiro Yasuda
An 80-year-old Japanese man presented to our hospital with intra-abdominal hemorrhage due to a ruptured liver tumor. Transcatheter arterial embolization (TAE) temporarily achieved hemostasis, but he died following re-rupture 4 days later. Based on autopsy findings, the liver tumor was diagnosed as hepatic angiosarcoma. Embolic agents used during embolization were identified within the hepatic small
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An Unusual Complication of Self-Expandable Metal Stent Placement in Malignant Sigmoid Obstruction. Case Rep. Gastroenterol. Pub Date : 2023-10-16 Qingjie Kang,Denghua Hu,Guangxu Wen,Zhengqiang Wei
Self-expandable metal stent (SEMS) for malignant colorectal obstruction is widely used as a bridge to elective surgery or palliative treatment. However, with the increasing use of SEMS for treatment, complication rates associated with stents have been raised as a concern. We experienced a rare migration-related complication that a stent partially migrated out of the anus with an incarceration. A 62-year-old
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Refractory Intestinal Behçet-Like Disease Associated with Trisomy 8 Myelodysplastic Syndrome Resolved by Parenteral Nutrition. Case Rep. Gastroenterol. Pub Date : 2023-10-11 Ryo Takahashi,Yasuo Matsubara,Satoshi Takahashi,Kazuaki Yokoyama,Lim Lay Ahyoung,Michiko Koga,Hiroyuki Sakamoto,Narikazu Boku,Dai Shida,Hiroshi Yotsuyanagi
Intestinal Behçet disease (BD), associated with myelodysplastic syndrome (MDS), is often refractory to treatment. An 80-year-old man with trisomy 8 MDS (refractory anemia) developed intermittent fever. Despite investigations to exclude infectious disease, autoimmune disease, and malignancy as the cause of the fever, the etiology could not be determined. A colonoscopy revealed several shallow round
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Ruptured Gastroduodenal Artery Pseudoaneurysms as a Complication of Pancreatitis. Case Rep. Gastroenterol. Pub Date : 2023-10-11 Haider Ghazanfar,Abhilasha Jyala,Sameer Datta Kandhi,Dongmin Shin,Kazi Samsuddoha,Harish Patel
Visceral artery pseudoaneurysms is a known vascular complication of pancreatitis that can lead to life-threatening hemorrhages with a high mortality rate if left untreated. We present a case of ruptured gastroduodenal artery pseudoaneurysm in a 68-year-old male with acute pancreatitis presenting with fatal gastrointestinal and retroperitoneal bleeding that was successfully managed with endovascular
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A Novel Presentation of Autoimmune Hepatitis with IgG1 Elevation. Case Rep. Gastroenterol. Pub Date : 2023-09-28 Yujiao Zhang,Bilal Niazi,Auda Auda,Angel Ann Chacko,Amer Jarri,Abdifatah Mohamed,Saad Ali,Hongfa Zhu,Syed Sirajuddin
Autoimmune hepatitis (AIH) is a common and debilitating pathology that has acute, subacute, and chronic presentation, requiring prompt diagnosis and early intervention. Several serologic markers are found to be associated with the pathogenesis and progression of autoimmune hepatitis, most notably antinuclear antibodies and anti-smooth muscle antibodies [Front Immunol. 2018;9:609]. In addition, AIH
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Systemic AA Amyloidosis Secondary to Metastatic Renal Cell Carcinoma in a Hemodialysis Patient with Intractable Diarrhea. Case Rep. Gastroenterol. Pub Date : 2023-09-13 Hiroyuki Endo,Noriyuki Obara,Shinichi Mizuno,Yasuhiro Nakamura
We describe an autopsied case of systemic AA amyloidosis secondary to metastatic renal cell carcinoma presenting intractable diarrhea. Severe diarrhea was the major symptom for the diagnosis of AA amyloidosis. No renal symptoms which are common in AA amyloidosis secondary to renal cell carcinoma were shown because hemodialysis following bilateral nephrectomy had already been started 9 years before
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An Asymptomatic Patient with Colonic Leiomyoma. Case Rep. Gastroenterol. Pub Date : 2023-09-12 Saad Alkhowaiter,Abdulmalik Alsheikh,Ammar Alotaibi
Subepithelial lesions (SELs) originating from muscularis mucosae of the colon are very rare findings on endoscopy. Appropriate management of SELs involves making a correct diagnosis and estimating their malignant potential. In this case study, a 58-year-old Saudi man presented with a small, 8-mm sigmoid polyp during screening colonoscopy. The polyp was removed by hot snare polypectomy and sent to pathology
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Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges. Case Rep. Gastroenterol. Pub Date : 2023-09-06 Junghyun Lim,Catherine Zaw,Simon Abramson,Paola N Lichtenberger,Binu V John,Lorena Cuebas-Rosado
Extracolonic manifestations of Clostridium difficile have been rarely reported. We herein report a case of a 60-year-old immunocompetent man presenting with fever, nausea, abdominal pain, and loose stools for 2 weeks. Triple-phase liver computed tomography demonstrated pyogenic liver abscesses and portal pylephlebitis. Blood cultures grew C. difficile and Bacteroides fragilis, and liver abscess cultures
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A Patient with Crohn's Disease Who Gave Birth Despite Sigmoid Volvulus, Venous Thrombosis, Nontraumatic Fracture of the Rib, and Sepsis during Pregnancy. Case Rep. Gastroenterol. Pub Date : 2023-08-16 Ayumi Ito,Maria Yonezawa,Shun Murasugi,Teppei Omori,Shinichi Nakamura,Katsutoshi Tokushige
The patient was a woman in her 40s who was diagnosed with Crohn's disease (CD) of the large and small intestines in 1996. In 2005, she was referred to our hospital for treatment. We treated her for 17 years with corticosteroids, biologics, immunosuppressive agents, 5-aminosalicylic acid, and nutrition care. However, her Crohn's Disease Activity Index remained between 200 and 250, indicating refractory
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Preoperative Diagnosis and Treatment of Cholecystoduodenal Fistula. Case Rep. Gastroenterol. Pub Date : 2023-08-09 Norio Yokoigawa,Yusai Kawaguchi
The case is about an 87-year-old female. While staying at a facility, she had a fever and abdominal pain and visited our hospital for an up-close examination and treatment. An abdominal CT scan revealed gallstones, gallbladder enlargement, and common bile duct stones. Endoscopic retrograde cholangiopancreatography was performed to confirm the presence of common bile duct stones, which were extracted
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Rectal Melanoma: Rare Cancer with Grave Prognosis. Case Rep. Gastroenterol. Pub Date : 2023-06-13 Khadija Soufi,Ferheen Abbasi,Dongguang Wei,Rashmi Verma
Malignant melanoma of the rectum is an exceedingly rare type of cancer with an aggressive presentation, comprising up to 4% of all anorectal cancers. Presentation of this cancer tends to occur in individuals in their late 80s, with nonspecific symptoms such as anal pain or rectal bleeding. Diagnosing rectal melanoma, especially in early stages, is difficult due to its amelanotic presentation and lack
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Gastrointestinal Eosinophilic Granulomatosis with Polyangiitis following a Clostridium difficile Infection. Case Rep. Gastroenterol. Pub Date : 2023-06-13 Haseeb Mohideen,Wegahta Weldemichael,Hafsa Hussain,Dushyant Singh Dahiya,Andrea Shin
Eosinophilic granulomatosis with polyangiitis (EGPA), historically named Churg-Strauss syndrome, is a rare vasculitis affecting small- and medium-sized blood vessels. The disease has a predilection for numerous organs including the lungs, sinuses, kidneys, heart, nerves, and gastrointestinal tract but is prominently associated with asthma, rhinosinusitis, and eosinophilia. Gastrointestinal involvement
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Gastric Metastasis 5 Years after Primary Invasive Lobular Adenocarcinoma of the Breast. Case Rep. Gastroenterol. Pub Date : 2023-06-06 Dongmin Shin,Haozhe Sun,Nikhitha Mantri,Harish Patel
Breast cancers metastasize most commonly to the bone, brain, liver, and lungs, but rarely to the gastrointestinal tract. Although metastatic breast carcinomas in the stomach can be confused with primary gastric cancers due to their nonspecific presentation and rare incidence, it is important to differentiate the two since the treatment is different. Clinical suspicion is imperative for a prompt endoscopic
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Right Hepatic and Portal Vein Embolization before Right Hepatectomy for Colorectal Cancer Liver Metastases. Case Rep. Gastroenterol. Pub Date : 2023-05-30 Eduardo E Montalvo-Javé,Edwin A Ayala-Moreno,Alejandro Rossano García,Alejandro Díaz Girón Gidi,Jorge Guerrero Ixtlahuac
Colon cancer has had a significant increase in its incidence in recent years. Many of the cases are diagnosed late; it is not unusual that a large number of cases present metastatic disease at the time of diagnosis, and the liver is the main organ where these lesions occur. Surgical approach to this condition has undergone many advances which have allowed a better approach to them. Local techniques
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Percutaneous Trans-Esophageal Gastrostomy for Oral Intake in a Case of Anastomotic Obstruction following Total Gastrectomy Case Rep. Gastroenterol. Pub Date : 2023-04-19 Masayuki Shishida, Daisuke Sumitani, Masatsugu Yano, Makoto Ochi, Yuzo Okamoto, Shigeto Yoshida, Kazuaki Tanabe, Hideki Ohdan
Gastric cancer is one of the most common diseases globally. Total gastrectomy is often performed surgically. However, late-stage anastomotic passage obstruction after total gastrectomy is relatively rare. Here, we report a case involving a 73-year-old male patient who experienced repeated aspiration pneumonia due to anastomotic passage obstruction 22 years after a total gastrectomy for gastric cancer
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Rectal Adenocarcinoma Presenting as a Perirectal Abscess Case Rep. Gastroenterol. Pub Date : 2023-04-19 Bibek Saha, Jared Dang, Melissa Kahili-Heede, James Grobe
Classic symptoms of rectal cancer (RC) such as hematochezia, tenesmus, rectal pain, and bowel habit changes are well known but can be nonspecific and misdiagnosed. Rare presentations, in combination with these conventional symptoms, can occur warranting a higher degree of clinical suspicion. Here, we report a case of rectal adenocarcinoma presenting as a perirectal abscess. A 52-year-old male with
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Nasogastric Tube Syndrome: A Severe Complication of Nasointestinal Ileus Tube Case Rep. Gastroenterol. Pub Date : 2023-04-13 Kenkichiro Taira, Satoshi Koyama, Tsuyoshi Morisaki, Takahiro Fukuhara, Ryouhei Donishi, Kazunori Fujiwara
Nasogastric tube syndrome (NGTS) induced by a nasointestinal ileus tube is an uncommon but potentially life-threatening complication. NGTS often becomes serious and progresses to acute upper airway obstruction caused by bilateral vocal cord paralysis or laryngeal infection. Early detection and proper treatment of NGTS are necessary. We describe the case of a 78-year-old patient with this syndrome induced
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Glomangiomyoma of the Stomach: Case Report Case Rep. Gastroenterol. Pub Date : 2023-04-11 Ouwais Alkhateb, Obada Daaboul, Bisher Daaboul, Raed Abouharb, Mhd Anas Alazmeh, Ghiath Hamed
Glomus tumor (glomus cell tumor) is a rare, often benign neoplasm, which is, in most cases, seen as a solitary bluish nodule involving the nail beds. Solid glomus tumor, glomangioma, and glomangiomyoma are the three main histopathological variants. In this case report, we present the rarest subtype of a glomus tumor, glomangiomyoma, in an atypical location: the stomach. A 45-year-old female from Syria
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Candesartan-Induced Enteropathy That Mimics Celiac Disease in a 90-Year-Old Patient Case Rep. Gastroenterol. Pub Date : 2023-04-06 Lydia ML Holtgrewe, Harald Dippel, Helgard Weckauf, Stephan Linnemüller, Frank Schuppert
Sprue-like enteropathy (SLE) is a clinical syndrome similar to celiac disease and has been associated with the use of various angiotensin receptor blockers (ARBs), a class of medications frequently used in the management of hypertension. Currently, there has only been one documented case report which has observed this occurrence with the use of the ARB candesartan. A 90-year-old female patient presented
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Carcinoid Heart Disease-Induced Right-Sided Heart Failure as a Culprit for Significant Ascites Case Rep. Gastroenterol. Pub Date : 2023-03-24 Yan Huang, Dae Yong Park, Anas Almoghrabi, Michael G. Nanna
The diagnosis of carcinoid heart disease as a cause of ascites can be hard to establish. We report a patient with well-differentiated neuroendocrine neoplasm of the liver who presented with high serum ascites albumin gradient and high protein ascites due to carcinoid heart disease (CHD). As ascites caused by CHD are rare, the etiology can easily be overlooked, especially in the setting of alcohol use
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Multiple Small Bowel Gastrointestinal Stromal Tumors Associated with Neurofibromatosis Type 1 that Were Not Detected by Endoscopy: A Case Report Case Rep. Gastroenterol. Pub Date : 2023-03-08 Satomi Saito, Teppei Omori, Shun Murasugi, Maria Yonezawa, Yukiko Takayama, Takeshi Ohki, Hiromi Onizuka, Yoji Nagashima, Katsutoshi Tokushige
We treated a 39-year-old Japanese man who was admitted for an abdominal mass. He had had neurofibroma-like skin lesions since childhood. Computed tomography and endoscopic ultrasound results were consistent with a tumor in the small intestine. Although the tumor was undetectable by single-balloon endoscopy, the patient’s background and imaging results led us to suspect a gastrointestinal stromal tumor
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Acute Late-Onset Cirrhosis in Zellweger Spectrum Disorder Case Rep. Gastroenterol. Pub Date : 2023-03-08 Mark Hsu, Amith Subhash
Zellweger spectrum disorders (ZSDs) are known to present with variable hepatic manifestations ranging from benign hepatosplenomegaly and elevated liver enzymes to advanced liver cirrhosis with hepatocellular carcinoma. However, the progression of liver disease in ZSD patients over time is poorly characterized due to scarcity of the disease. Herein, we report a case of newly diagnosed liver cirrhosis
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Delayed Perforation of Colorectal Endoscopic Submucosal Dissection Treated by Endoscopic Ultrasound-Guided Drainage Case Rep. Gastroenterol. Pub Date : 2023-03-03 Koichi Hamada, Yoshiki Shiwa, Akira Kurita, Yukitoshi Todate, Yoshinori Horikawa, Kae Techigawara, Masafumi Ishikawa, Takayuki Nagahashi, Yuki Takeda, Daizo Fukushima, Noriyuki Nishino, Hideo Sakuma, Michitaka Honda
We report a case of a 70-year-old male with delayed perforation in the cecum treated by endoscopic ultrasonography-guided drainage for a pelvic abscess. The lesion was a 50-mm laterally spreading tumor, and endoscopic submucosal dissection (ESD) was performed. No perforation was detected during the operation, and en bloc resection was achieved. He had fever and abdominal pain on postoperative day (POD)
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Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response Case Rep. Gastroenterol. Pub Date : 2023-03-03 Mark Lai, Tony He, Emily K. Wright
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case of EGPA-related pancolitis and stricturing small bowel disease managed with a combination of mepolizumab and surgical resection. Case
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Leukocytoclastic Vasculitis Associated with Adalimumab Therapy for Crohn’s Disease Case Rep. Gastroenterol. Pub Date : 2023-03-01 Lankai Cathy Xu, Sirisha Grandhe, Joseph G Marsano
Leukocytoclastic vasculitis (LCV) is rarely associated with anti-tumor necrosis factor [TNF] α therapy. We report a 22-year-old man with new onset of a pustular rash on his bilateral upper and lower extremities while on adalimumab therapy for Crohn’s disease. Skin biopsy of the affected area showed perivascular extravasation of erythrocytes, neutrophils, eosinophils and vascular damage surrounding
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Retroperitoneal and Mediastinal Emphysema after Sigmoid Colon Resection Case Rep. Gastroenterol. Pub Date : 2023-02-23
Retroperitoneal and mediastinal emphysema after colon resection is extremely rare, especially in the absence of anastomotic leakage. The feasibility and safety of conservative treatment for this complication are unknown. We report a patient who underwent open sigmoid colon resection for colon cancer and developed retroperitoneal and mediastinal emphysema that was not caused by anastomotic leakage.
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Early Onset Outlet Obstruction of a Temporary Diverting Loop Ileostomy Secondary to Urinary Retention Case Rep. Gastroenterol. Pub Date : 2023-02-22 Umut Akova, Volkan Dogru, Eren Esen, Feza Remzi
A mechanical obstruction is not a physiological entity, and when it occurs within the 30-day postoperative period, it is called an early postoperative small bowel obstruction. Kinking of small bowel segments at the ileostomy outlet secondary to a distended bladder is an unusual source of early postoperative small bowel obstruction. A 36-year-old female underwent a redo J-Pouch surgery and creation
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Metastasis of Ovarian Cancer to the Descending Colon Case Rep. Gastroenterol. Pub Date : 2023-02-22 Kentaro Abe, Hiroyuki Anzai, Satoko Eguchi, Masako Ikemura, Aya Shinozaki-Ushiku, Takahide Shinagawa, Hirofumi Sonoda, Yuichiro Yoshioka, Yuzo Nagai, Shinya Abe, Hiroyuki Matsuzaki, Yuichiro Yokoyama, Shigenobu Emoto, Koji Murono, Kazuhito Sasaki, Hiroaki Nozawa, Tetsuo Ushiku, Soichiro Ishihara
Colonic metastasis from ovarian cancer is extremely rare, with only seven reported cases. A 77-year-old woman who had previously undergone surgery for ovarian cancer was admitted to a local hospital with anal bleeding. Histopathological analysis confirmed the presence of adenocarcinoma. Colonoscopy revealed a descending colon tumor. The patient was diagnosed with Union for International Cancer Control
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Granular Cell Tumor of the Ascending Colon Case Rep. Gastroenterol. Pub Date : 2023-02-17 Samyak Dhruv, Kuldeepsinh P. Atodaria, Dhineshreddy Gurala, Talal El Imad, Jeffrey Abergel
Granular cell tumor (GCT) was first described by Abrikossoff in 1926. It is a mostly benign tumor with rare malignant transformation. It is defined as a soft tissue neoplasm with abundant eosinophilic cytoplasm. The mean age of diagnosis for GCT is around 45 years. It is rare for GCT to be found in the gastrointestinal (GI) tract. Within the subset of GI tract, the colon is an extremely rare site for
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Benefit of Continuation of Low-Dose Imatinib for Gastrointestinal Stromal Tumors despite Adverse Events with Regular-Dose Imatinib Case Rep. Gastroenterol. Pub Date : 2023-02-17 Ryo Katsumata, Yasumasa Monobe, Yosuke Katata, Hideyo Fujiwara, Takashi Urano, Akihisa Akagi, Kotone Tsujimoto, Takako Konishi, Noriaki Manabe, Tomoari Kamada, Hirofumi Kawamoto, Tomoki Yamatsuji, Yoshio Naomoto
Tyrosine kinase inhibitors (TKIs) such as imatinib improve the prognosis of patients with gastrointestinal stromal tumors (GISTs). However, treatment options for GISTs are still limited, and the continuation of TKIs is difficult due to adverse events in some cases. The effectiveness of low-dose imatinib is unclear. We report 2 cases to show effectiveness of low-dose imatinib in patients with adverse
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A Case of Autoimmune Gastritis and Hepatitis with Enlarging Gastric Polyps after Reducing the Dose of Prednisolone Case Rep. Gastroenterol. Pub Date : 2023-02-17 Ryo Katsumata, Tomoari Kamada, Takahisa Murao, Aya Sunago, Mitsuhiko Suehiro, Yasumasa Monobe, Yoshiaki Iwasaki, Hirofumi Kawamoto, Hiroshi Nagai, Ken Haruma
Autoimmune gastritis is immune-mediated gastritis that destroys the oxyntic mucosa. Autoimmune hepatitis is an inflammatory liver disease caused by an autoimmune reaction. These diseases share similar pathogeneses as organ-specific autoimmune disorders; however, cases involving both diseases are quite rare and scarcely reported. Herein, we report a patient with concurrent autoimmune gastritis and hepatitis
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The Role of Host in the Spectrum of Outcomes in Family Clusters of Hepatitis Infection: From Asymptomatic to Hepatocellular Carcinoma Case Rep. Gastroenterol. Pub Date : 2023-02-14 Nicholas Noverati, Anh Nguyen, Divya Chalikonda, Dina Halegoua-DeMarzio, Hie-Won Hann
Hepatitis B virus infections are prevalent worldwide, but the outcomes of infection vary greatly from host to host. In many endemic regions, vertical transmission from mother to child is most common. In this transmission setting, virus genotype and shared patient genetics make for an interesting comparison of outcome of chronic hepatitis B infection. This case series demonstrates four family clusters
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Non-Intentional N-Acetylcysteine Overdose Associated with Cerebral Edema and Brain Death Case Rep. Gastroenterol. Pub Date : 2023-02-08 Emma E.M. Spence, Sey Shwetz, Lauren Ryan, Natalie Anton, Ari R. Joffe
N-acetylcysteine is the established treatment for acetaminophen toxicity. This medication’s complex dosing schedule engenders a high incidence of medication errors. While nuisance side effects are common, only rare case reports describe serious outcomes associated with N-acetylcysteine administration, all of which take place in the setting of non-intentional N-acetylcysteine overdose. This case report
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Traditional Serrated Adenoma of the Ileum with Intussusception Successfully Treated with Laparoscopic Bowel Resection Case Rep. Gastroenterol. Pub Date : 2023-02-07
The most common site of traditional serrated adenomas (TSA) is the area from the left colon to the rectum; however, there are few reports on TSA in the small intestine. Herein, we report a case of TSA of the ileum with intussusception that was diagnosed and successfully treated with laparoscopic bowel resection. The patient was a 29-year-old female with the chief complaint of recurrent abdominal pain
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Colonic Dilatation Complicating Acute Severe Ulcerative Colitis Managed Successfully with Accelerated Infliximab Dosing Case Rep. Gastroenterol. Pub Date : 2023-02-07 Hoang Huu Bui, Luan Minh Dang, Diem Thi-Ngoc Vo, Chuong Dinh Nguyen
Lately, emerging data suggest an association between the development of inflammatory bowel disease and anti-interleukin-17 therapy. Megacolon is a life-threatening complication of acute severe ulcerative colitis (ASUC), but its treatment has not yet been established in current practice guidelines. We report a rare case of known psoriasis treated by secukinumab in a patient who presented with ASUC and
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Endoscopic Hemostatic Treatment for Acute Gastrointestinal Bleeding by Combined Modality Therapy with PuraStat and Endoscopic Hemoclips Case Rep. Gastroenterol. Pub Date : 2023-02-07 Kimitoshi Kubo, Shuhei Hayasaka, Ikko Tanaka
Acute gastrointestinal bleeding (AGIB) is a common condition leading to hospitalization and is associated with significant morbidity and mortality. Various endoscopic treatments have been reported for AGIB, while its endoscopic hemostasis treatment by combined modality with PuraStat and endoscopic hemoclips remains less well documented. We report 6 cases of AGIB, i.e., 5 cases of ulcer bleeding and
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Traditional Serrated Adenoma of the Ileum with Intussusception Successfully Treated with Laparoscopic Bowel Resection. Case Rep. Gastroenterol. Pub Date : 2023-02-07 Ryo Nishide,Teppei Kamada,Junji Takahashi,Keigo Nakashima,Eisaku Ito,Yuichi Nakaseko,Norihiko Suzuki,Masashi Yoshida,Hironori Ohdaira,Yutaka Suzuki
The most common site of traditional serrated adenomas (TSA) is the area from the left colon to the rectum; however, there are few reports on TSA in the small intestine. Herein, we report a case of TSA of the ileum with intussusception that was diagnosed and successfully treated with laparoscopic bowel resection. The patient was a 29-year-old female with the chief complaint of recurrent abdominal pain
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Normal Splanchnic Blood Flow in a Patient with Severe Stenosis of the Celiac Artery and Superior Mesenteric Artery Case Rep. Gastroenterol. Pub Date : 2023-02-03
The diagnosis of chronic mesenteric ischaemia is typically based on angiographic findings along with a classic symptomatology. Only a few methods are available for functional testing to establish the diagnosis, such as indirect measurement of the splanchnic blood flow and hepatic vein oxygenation. The present case is a 76-year-old woman with weight loss and intermittent abdominal pain who was clinically
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Progression of Recurrent Pancreatitis to Chronic Pancreatitis within 3 Years due to SPINK1 Mutation IVS3+2T>C Case Rep. Gastroenterol. Pub Date : 2023-01-27 Susumu Horitani, Masahiro Tsujimae, Arata Sakai, Atsuhiro Masuda, Kae Nagao, Shinya Kohashi, Noriko Inomata, Hisahiro Uemura, Shigeto Masuda, Masanori Gonda, Shohei Abe, Kohei Yamakawa, Shigeto Ashina, Yasutaka Yamada, Takeshi Tanaka, Ryota Nakano, Takashi Kobayashi, Hideyuki Shiomi, Yuzo Kodama
When the etiology of pancreatitis cannot be determined despite sufficient investigation, recurrence and progression to chronic pancreatitis often involve genetic mutations. Herein, we describe a case of recurrent pancreatitis with the IVS3+2Tgt;C mutation in the serine protease inhibitor Kazal type 1 (SPINK1) gene that progressed to chronic pancreatitis in only 3 years. A 35-year-old man was referred
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A Patient with Transverse Colon Cancer Complicated by Cowden Syndrome Administered FOLFOXIRI + Bevacizumab Therapy Case Rep. Gastroenterol. Pub Date : 2023-01-27 Kazuhiro Takehara, Yoichi Ishizaki, Kunihiko Nagakari, Masakazu Ohuchi, Masaki Fukunaga, Kazuhiro Sakamoto
Cowden syndrome is characterized by several clinical features related to tumorous lesions primarily consisting of systemic hamartomas. The mutation of a tumor suppressor gene, the PTEN gene, is etiologically involved. As gastrointestinal lesions, polyps of all digestive tracts involving the esophagus to rectum develop. In patients with Cowden syndrome, the risk of colorectal cancer may increase. However
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Regression of Autoimmune Gastritis after Eradication of Helicobacter pylori Case Rep. Gastroenterol. Pub Date : 2023-01-10 Tohru Kotera, Yurika Nishimi, Ryoji Kushima, Ken Haruma
We report a case of autoimmune gastritis (AIG) in which gastric mucosal atrophy improved with Helicobacter pylori eradication. Based on endoscopic findings (advanced gastric atrophy with vascular visibility and diffuse redness in remnant oxyntic mucosa), a woman in her 40s was suspected of having AIG coexisting with an active H. pylori infection. This was confirmed by a positive anti-parietal cell
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Hypereosinophilic Syndrome Secondary to Ulcerative Colitis and Primary Sclerosing Cholangitis Case Rep. Gastroenterol. Pub Date : 2023-01-10 Davi Viana Ramos, Diogo Delgado Dotta, Luísa Leite Barros
Hypereosinophilic syndrome (HES) is a rare condition characterized by hypereosinophilia in peripheral blood or tissue infiltrate and organ damage. HES has been associated with several diseases, including inflammatory bowel diseases (IBDs), especially ulcerative colitis (UC). In this report, we describe a case of a UC and primary sclerosing cholangitis patient who was diagnosed with HES and severe cardiovascular
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Helicobacter pylori Reinfection Diagnosed by Endoscopic and Histologic Recurrence in a Patient with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Case Rep. Gastroenterol. Pub Date : 2023-01-10 Toshiro Sugiyama, Sohachi Nanjo, Takahiko Nakajima, Chieko Kato
Helicobacter pylori infection is a major cause of gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Successful H. pylori eradication can induce a complete remission (CR); however, it takes a long time. In this case, the recurrence of gastric MALT lymphoma was observed by endoscopic and histologic findings during a 11-year follow-up and due to H. pylori reinfection twice. After the first successful
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Intraductal Papillary Mucinous Neoplasm of the Pancreas Associated with Polycystic Liver and Kidney Disease Case Rep. Gastroenterol. Pub Date : 2023-01-09 Norio Yokoigawa, Yusai Kawaguchi
A 77-year-old man was pointed out thrombocytopenia and polycystic liver and kidney disease following hypertension and diabetes mellitus and duodenitis. He consulted to our hospital for further examination. Computed tomography (CT) showed multiple cysts in the liver and kidney and also showed cystic lesions in the pancreatic tail. The size of the tumor of pancreas was 3 cm × 4 cm. FDG-PET CT showed
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Onset of Oral Lichen Planus Led to Direct-Acting Antiviral Therapy in a Patient with Long-Term Hepatitis C: The Role of a Dentist as Gatekeeper Case Rep. Gastroenterol. Pub Date : 2023-01-09 Yumiko Nagao, Masahide Tsuji
Oral lichen planus (OLP), a chronic inflammatory mucocutaneous disease, is an extrahepatic manifestation of a hepatitis C virus infection. In recent years, direct-acting antivirals (DAAs) have made great strides in the treatment of hepatitis C. However, there might be a lack of information about the treatment strategies available among those with this condition. Herein, we report a case of an 85-year-old
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Distinction between Mitochondrial Antibody-Positive and -Negative Primary Biliary Cholangitis Case Rep. Gastroenterol. Pub Date : 2023-01-06 Venkata Vinod Kumar Matli, David F Dies, Sudha Pandit, Gregory Wellman, James D. Morris
Antimitochondrial antibody-positive primary biliary cholangitis (AMA-pos PBC) is an autoimmune disorder in which monoclonal antibodies are produced against epitopes in the mitochondrial membranes of biliary epithelial cells, resulting in progressive nonsuppurative biliary cholangitis. Up to 5% of patients lack these autoantibodies, termed antimitochondrial antibody-negative (AMA-neg) PBC. Although
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Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis Case Rep. Gastroenterol. Pub Date : 2023-01-03 Shinya Sugimoto, Tomohito Fuke, Daisuke Kobayashi, Mamika Kaneko, Taishi Temma, Tatsuma Nomura, Nobuyuki Tsuda, Mayu Kawabata, Ryutaro Matsushima, Hirohisa Hisada, Satoshi Hayashi, Toji Murabayashi, Jun Oyamada, Akira Kamei, Nobukazu Fuwa, Tadashi Yabana, Hiroyuki Yamada, Hayato Nakagawa
We report 4 cases of hypopharyngeal cancer preoperatively suspected with synchronous lymph node metastases. Pathologic lymph node metastasis was confirmed in three of the four cases. All 4 cases underwent endoscopic laryngopharyngeal surgery (ELPS) combined with endoscopic submucosal dissection (ESD) and subsequent lymph node dissection as an optional treatment rather than the standard treatment. Peroral
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Understanding the Presentation of Terminal Ileitis Case Rep. Gastroenterol. Pub Date : 2022-12-27 Ashali Jain, Xiaolan Tang, Tyler Jones, Sripal Aditya Padam
Our patient is a 47-year-old African American female with a past medical history of recurrent episodes of small bowel obstruction. She presented to the emergency department with symptoms of nausea, vomiting, and abdominal pain. Upon further evaluation, imaging showed obstruction at the terminal ileum. Based on the holistic clinical presentation, we initially thought that this patient was experiencing
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Impacted Common Bile Duct Stone Managed by Hepaticoduodenostomy Case Rep. Gastroenterol. Pub Date : 2022-12-21 Elroy Patrick Weledji, Ndiformuche Zikirou Mbengawoh, Frank Zouna
A bypass procedure such as a hepaticoduodenostomy may be an alternative to the traditional choledochoduodenostomy in the management of the retained, impacted distal common bile duct (CBD) stone, especially in the presence of sepsis. We present herein a hepaticoduodenotomy performed for a retained, impacted distal CBD stone in a low-resource setting with a good outcome. This impacted stone had complicated
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Diagnosis and Management of Lemmel Syndrome: An Unusual Presentation and Literature Review Case Rep. Gastroenterol. Pub Date : 2022-12-16 James Stephen Love, Meredith Yellen, Constantine Melitas, Cemal Yazici, Fred Zar
Lemmel syndrome is a rare clinical entity characterized by the presence of a periampullary duodenal diverticulum resulting in compression and dilatation of the pancreatic and common bile ducts, accompanied by obstructive jaundice. Gastric outlet obstruction is not a known complication of this syndrome, and there are no standardized approaches to its treatment. We present the first case of Lemmel syndrome
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Left Perforated Colonic Tumor with Synchronous Locally Advanced Right Colonic Tumor Case Rep. Gastroenterol. Pub Date : 2022-12-05 Marco Antonio Robles González, Marcela Pérez Villaseñor, Ana Alfaro Cruz, Sergio Ulises Pérez Escobedo, Yanetzy Elizabet Corona Flores
Colorectal cancer is one of the most common malignant neoplasms worldwide. Overall mortality is 33%. Synchronous colorectal cancer refers to more than one malignant tumor detected in different segments of the colon, simultaneously or within 6 months of initial diagnosis. The development of colorectal cancer is a multistep process that originates with a genetic mutation leading to a malignant phenotype
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Mixed Neuroendocrine Non-Neuroendocrine Neoplasm Arising in the Ectopic Gastric Mucosa of Esophagus Case Rep. Gastroenterol. Pub Date : 2022-12-05 Ryosuke Gushima, Hideaki Miyamoto, Miyuki Imamura, Takayoshi Sonoda, Kenshi Matsuno, Akira Yamasaki, Yoki Furuta, Shunpei Hashigo, Masakuni Tateyama, Hideaki Naoe, Yasuhito Tanaka
Esophageal neuroendocrine neoplasms are extremely rare, and their prognosis is poor. Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) are even more rare and are defined as tumors consisting of neuroendocrine carcinoma and either adenocarcinoma or squamous cell carcinoma. We report a rare case featuring endoscopic submucosal dissection (ESD) for an esophageal MiNEN, arising from the ectopic
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A Novel Treatment Approach to Treatment-Resistant, Recurrent Clostridium difficile Case Rep. Gastroenterol. Pub Date : 2022-12-05 Megha Gangadhar, Anita Kottapalli, Ven Kottapalli
A 36-year-old male with a previous medical history of persistent Clostridium difficile presented to clinic for evaluation of diarrheal symptoms intermittently for the last 2 years. He reported recurrent episodes of C. difficile that initially began after prophylactic antibiotic use prior to a tooth extraction. He underwent 12 unsuccessful treatment trials at a nearby clinic with courses of vancomycin
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Microscopic Colitis with Escitalopram Use and New Onset Vitiligo Case Rep. Gastroenterol. Pub Date : 2022-11-28 Humzah Iqbal, Rakahn Haddadin
Microscopic colitis is a common cause of chronic diarrhea, particularly in patients with autoimmune disorders. Colonic mucosa appears normal and only shows inflammation on histological examination. There are two histological variations of microscopic colitis. It has been associated with several drug classes, and certain drugs are associated with one variation or another. In this case report, we discuss