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Association between BMI and efficacy of SGLT2 inhibitors in patients with heart failure or at risk of heart failure: a meta-analysis based on randomized controlled trials. Cardiology (IF 1.9) Pub Date : 2023-11-24 Yisheng Zhou,Min Dai,Tongmin Huang,Bangsheng Chen,Zhiyi Xiang,Jiawen Tang,Meixia Zheng,Luyong Guo
INTRODUCTION This meta-analysis aimed to investigate the effect of SGLT2 inhibitors on the prognosis in patients with heart failure (HF) or at risk of heart failure across different body mass index (BMI). METHODS We searched PubMed, Embase, Web of Science, and Cochrane Library for all randomized controlled trials (RCTs) comparing SGLT2 inhibitors with placebo in patients with HF or at risk of HF and
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Association between impaired renal function and subclinical myocardial dysfunction in patients with heart failure with preserved ejection fraction: assessment using noninvasive pressure-strain loop. Cardiology (IF 1.9) Pub Date : 2023-11-23 Mingming Lin,Yunyun Qin,Xueyan Ding,Miao Zhang,Weiwei Zhu,Dichen Guo,Jiangtao Wang,Xiuzhang Lu,Qizhe Cai
PURPOSE To evaluate the abnormal myocardial function in HFpEF patients with renal dysfunction and investigate the relationship between renal function and myocardial mechanical characteristics in patients with HFpEF. METHODS 134 patients with HFpEF and 32 control subjects were enrolled in our study. Clinical and echocardiography data were collected for offline analysis. Global work index(GWI), global
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Developing and validating a simple risk score for patients with acute myocardial infarction. Cardiology (IF 1.9) Pub Date : 2023-11-22 Zheng-Yang Ge,Yang He,Ting-Bo Jiang,Jian-Ying Tao,Yong-Ming He
INTRODUCTION Mortality from acute myocardial infarction (AMI) remains substantial. The current study is aimed at developing a novel simple risk score for AMI. METHODS The Coronary Artery Tree description and Lesion EvaluaTion (CatLet) extended validation trial (ChiCTR2000033730) and the CatLet validation trial (ChiCTR-POC-17013536), both being registered with chictr.org, served as the derivation and
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Bempedoic acid - how will it shape the future lipid-lowering landscape? Mode of action, evidence, and clinical use. Cardiology (IF 1.9) Pub Date : 2023-11-21 Heinz Drexel,Arthur Mader
Background Low density lipoproteins are now proven to be causal for atherosclerosis. Pharmacological treatment focuses on an increase of LDL receptors, particularly in the hepatocyte, which leads to uptake of LDL from blood, thereby reducing the burden to the arterial wall. This mechanism has first been proven by statins to be effective to reduce cardiovascular morbidity and mortality. The concept
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The Cockroach of Critical Care: Atrial Fibrillation and Predictors in the ICU Setting. Cardiology (IF 1.9) Pub Date : 2023-11-15 Dustin Staloch,Michael S Lloyd
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Comment on: "Plasma Cell-Free DNA Is a Potential Biomarker for Diagnosis of Calcific Aortic Valve Disease". Cardiology (IF 1.9) Pub Date : 2023-11-15 Kasinathan Kumaran,Kandasamy Nagarajan ArulJothi
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Prevalence and impact of frailty in patients ≥70 years old with acute coronary syndrome referred for coronary angiography. Cardiology (IF 1.9) Pub Date : 2023-11-10 Hanna Ratcovich,Francis R Joshi,Pernille Palm,Jane Færch,Lia E Bang,Hans-Henrik Tilsted,Golnaz Sadjadieh,Thomas Engstrøm,Lene Holmvang
Introduction Elderly patients with acute coronary syndrome (ACS) have a higher risk of adverse cardiovascular events and may be frail but are underrepresented in clinical trials. Previous studies have proposed that frailty assessment is a better tool than chronological age, in assessing older patients' biological age, and may exceed conventional risk scores in predicting prognosis. Therefore, we wanted
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Association between troponin elevation and decreased myocardial blood flow reserve in patients without obstructive coronary artery disease. Cardiology (IF 1.9) Pub Date : 2023-11-09 Ning Yang,Rongzhen Zhang,Chaoqun Zhao,Bochen Sun,Biyu Wang,Yuwei Song,Shuhan Qi,Jianan Liu,Yujia Sun,Hui Liu,HuanHuan An,Xingyue Zhang,Fei Xiang,Qinghui Yang,Wei Han
INTRODUCTION To study the prognostic factors of patients with chest pain and without obstructive coronary artery disease is of great significance for the management of such patients. We assessed whether a high-sensitivity troponin I (hs-TnI) is associated with prognosis in patients with chest pain and without obstructive coronary artery disease. METHODS From 2011 to 2017, 489 consecutively hospitalized
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Correlation of plasma adiponectin levels and adiponectin gene polymorphisms with idiopathic atrial fibrillation. Cardiology (IF 1.9) Pub Date : 2023-11-08 Fang Chen,Yuqin Ye,Guosheng Wu,MeiFang Wu
INTRODUCTION Adiponectin is a cellular protein secreted by adipocytes, which is closely related to a variety of diseases, including atrial fibrillation(AF). Idiopathic atrial fibrillation(IAF) is defined as AF without hypertension, diabetes and other underlying diseases.Genetic polymorphism of adiponectin affects serum adiponectin concentration. However, the association of serum adiponectin concentration
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Striking Variations in Aortic Valve Replacement Rates and Use of Transcatheter Aortic Valve Implantation among European Nations. Cardiology (IF 1.9) Pub Date : 2023-11-06 Dominik Buckert,Marvin Krohn-Grimberghe,Wolfgang Rottbauer
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Plasma Cell-free DNA is a potential biomarker for diagnosis of calcific aortic valve disease. Cardiology (IF 1.9) Pub Date : 2023-10-27 Wangge Ma,Wei Zhang,Huahua Liu,Benheng Qian,Rongguang Lai,Zijun Yao,Yidong Wang,Yang Yan,Zuyi Yuan
BACKGROUND Calcific aortic valve disease (CAVD) is the third most common cardiovascular disease in aging populations. Despite a growing number of biomarkers having been shown to be associated with CAVD, a marker suitable for routine testing in clinical practice is still needed. Plasma cell-free DNA (cfDNA) has been suggested as a biomarker for diagnosis and prognosis in multiple diseases. In this study
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Cardiac Biomarkers in Dyspnea Hospitalizations - Still Breathing Not Predictively. Cardiology (IF 1.9) Pub Date : 2023-10-26 Manyoo A Agarwal,Wael AlMahmeed,Javed Butler
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Quantitative flow ratio‑derived index of microcirculatory resistance as a novel tool to identify microcirculatory function in patients with ischemia and no obstructive coronary artery disease (INOCA). Cardiology (IF 1.9) Pub Date : 2023-10-14 Beibei Gao,Guomin Wu,Jianchang Xie,Jie Ruan,Peng Xu,Yufeng Qian,Junjie Gu,Wei Li,Xiangbo Jin,Guoxin Tong,Jinyu Huang
BACKGROUND Coronary microvascular disease (CMVD) is associated with adverse cardiovascular outcomes. However, there is no reliable and noninvasive quantitative diagnostic method available for CMVD. The use of a pressure wire to measure the index of microcirculatory resistance (IMR) is possible, but it has inevitable practical restrictions. We hypothesized that computation of the quantitative flow ratio
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The balance of CD8-positive T cells and PD-L1 expression in the myocardium predicts prognosis in lymphocytic fulminant myocarditis. Cardiology (IF 1.9) Pub Date : 2023-10-12 Hiroaki Hiraiwa,Ryota Morimoto,Yuta Tsuyuki,Kaori Ushida,Ryota Ito,Shingo Kazama,Yuki Kimura,Takashi Araki,Takashi Mizutani,Hideo Oishi,Tasuku Kuwayama,Toru Kondo,Takahiro Okumura,Toyoaki Murohara
INTRODUCTION The clinical significance and prognostic value of T cell involvement and programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) have not been established in lymphocytic fulminant myocarditis (FM). We investigated the prognostic impact of the number of CD4+, CD8+, FoxP3+, and PD-1+ T cells, as well as PD-L1 expression, in cardiomyocytes in lymphocytic FM. METHODS This is
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Feasibility Of Noninvasive Assessment of Cardiac Output During Exercise In Healthy Adults By A Novel Elaboration On Systolic Time Intervals. Cardiology (IF 1.9) Pub Date : 2023-10-12 Chul-Ho Kim,Bradley S Cierzan,Nisha Patel,Barry A Borlaug,Bruce D Johnson
INTRODUCTION Although assessment of cardiovascular hemodynamics during exercise can provide clinical insights, it is challenging to acquire it in clinical settings. Accordingly, this preliminary study was to determine whether a novel elaboration on Systolic Time Interval measures (eSTICO) method of quantifying Cardiac Output and Stroke Volume was comparable to those obtained using a validated soluble
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Predictors of new onset atrial fibrillation burden in the critically ill. Cardiology (IF 1.9) Pub Date : 2023-10-07 Daniel Lancini,Jennifer Sun,Georgia Mylonas,Robert Boots,John Atherton,Sandhir Prasad,Paul Martin
Introduction Atrial fibrillation (AF) is common in the intensive care unit (ICU) setting, and has been associated with adverse outcomes. In this context, there is increasing research interest in AF burden as a predictor of subsequent adverse events. However, the pathophysiology and drivers of AF burden in ICU are poorly understood. This study sought to evaluate the predictors of AF burden in critical
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Atrial Fibrillation and Frailty: A Look into the Future of Two Rising Conditions. Cardiology (IF 1.9) Pub Date : 2023-09-29 Giulio Binaghi,Matteo Casula
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Measuring What Matters Most in Aortic Stenosis: Is It Time for Disease-Specific Measurement? Cardiology (IF 1.9) Pub Date : 2023-09-19 Britt Borregaard,Sandra B Lauck
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Impact of Isolated Coronary Microvascular Disease Diagnosed Using Various Measurement Modalities on Prognosis: An Updated Systematic Review and Meta- Analysis. Cardiology (IF 1.9) Pub Date : 2023-09-14 Xingyu Luo,Yaokun Liu,Jiahui Liu,Jin Zhang,Songyuan Gao,Yanyan Zhang,Zuoyi Zhou,Haotai Xie,Weijie Hou,Yan Jun Gong,Bo Zheng,Yan Zhang,Jianping Li
INTRODUCTION The main aim of this study was to investigate the impact of isolated coronary microvascular disease (CMD) as diagnosed via various modalities on prognosis. METHOD A systematic literature review of PubMed, Embase, and Cochrane library databases was conducted to identify relevant studies published up to March 2023. Included studies were required to measure coronary microvascular function
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More on the Magic of Metformin. Cardiology (IF 1.9) Pub Date : 2023-09-06 Efstratios Koutroumpakis,Claire Huang-Lucas,Heinrich Taegtmeyer
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Long-Term Change in Flow Rates in Patients with Coronary Slow Flow. Cardiology (IF 1.9) Pub Date : 2023-08-26 Gokturk Ipek,Tugay Kamber,Hale Yilmaz,Osman Bolca
BACKGROUND Coronary slow flow (CSF) is a condition characterized by impaired blood flow rates in the coronary arteries. It can result in severe cardiovascular outcomes. There is not sufficient evidence regarding the certain etiology and reversibility of slow flow patterns and change in frame counts with long-term management. METHODS We retrospectively enrolled 48 patients with chronic coronary syndrome
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Pathological interplay and clinical complications between COVID-19 and cardiovascular diseases: an overview in 2023. Cardiology (IF 1.9) Pub Date : 2023-08-16 Sufeng Zhou,Anchen Zhang,Hua Liao,Zhebo Liu,Feiyan Yang
The coronavirus disease 2019 (COVID-19) involves all organs of the body, of which the interaction with cardiovascular diseases is the most important. Numerous studies have reported that COVID-19 patients complicated with cardiovascular comorbidities (hypertension, coronary heart disease, chronic heart failure, cerebrovascular disease) are more likely to develop into critical illness and have higher
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Patterns of Aortic Valve Replacement in Europe: Adoption by Age. Cardiology (IF 1.9) Pub Date : 2023-08-16 Tanja Rudolph,Clare Appleby,Victoria Delgado,Helene Eltchaninoff,Catherine Gebhard,Christian Hengstenberg,Wojtek Wojakowski,Nathan Petersen,Jana Kurucova,Peter Bramlage,Sabine Bleiziffer
INTRODUCTION The management of patients with severe aortic stenosis (AS) may differ according to patient age. The aim of this analysis was to describe patterns of aortic valve replacement (AVR) use in European countries stratified by age. METHODS Procedure volume data for AVR, including surgical aortic valve replacement (sAVR) and transcatheter aortic valve implantation (TAVI), for the years 2015-2020
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Troponin T and N-terminal pro-brain natriuretic peptide are associated with long-term all-cause mortality in patients with post-sternotomy mediastinitis following coronary artery bypass grafting: A 15-year follow-up study. Cardiology (IF 1.9) Pub Date : 2023-08-16 Ivar Risnes,Pål Aukrust,Runar Lundblad,Thor Ueland,Stein Erik Rynning,Eivind Solheim,Sahrai Saeed
BACKGROUND Deep sternal wound/mediastinitis is a rare but feared complication in CABG (coronary artery bypass grafting) patients and seems to increase the risk of cardiac death, and is also associated with the risk of early internal mammary artery (IMA) graft obstruction. The pathological mechanism explaining the link between mediastinitis and IMA graft obstruction and the impact on mortality is complex
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Understanding the heart failure evolution as an important step towards optimized treatment. Cardiology (IF 1.9) Pub Date : 2023-08-10 Marko Banovic
Heart failure is a dynamic syndrome with changing clinical trajectories. This dynamics may be captured in several ways, including alterations in cardiac structure and function and by patient' clinical status. The meticulous and long-term follow-up, together with continuation of medical treatment or by applying interventional treatment procedures where possible and reasonable, is recommended to ensure
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OBESITY PARADOX IN THE INTRAHOSPITAL AND FOLLOW-UP PHASES OF THE ACUTE CORONARY SYNDROME: A META-ANALYSIS AND SYSTEMATIC REVIEW. Cardiology (IF 1.9) Pub Date : 2023-08-08 Marko Mornar Jelavic,Zdravko Babic,Hrvoje Pintaric
INTRODUCTION This meta-analysis brings comprehensive evaluation about still controversial association between the body mass index (BMI) and the outcomes of acute coronary syndrome (ACS). METHODS PubMed/ScienceDirect databases were systematically searched for studies with baseline parameters, primary (heart failure (HF), cardiogenic shock, cardiac arrest, reinfarction, stroke, death, total in-hospital
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Frailty predicts incident atrial fibrillation in women but not in men: The Kuopio Ischaemic Heart Disease Risk Factor Study. Cardiology (IF 1.9) Pub Date : 2023-08-05 Behnam Tajik,Ari Voutilainen,Arja Lyytinen,Jussi Kauhanen,Gregory Y H Lip,Tomi-Pekka Tuomainen,Masoud Isanejad
INTRODUCTION Frailty and atrial fibrillation (AF) are common aging problems and increasing globally. The association(s) between frailty and AF have been inconclusive. The purpose of this prospective population-based cohort was to investigate the associations between frailty and incident atrial fibrillation (AF) in older men and women. METHODS In total 839 participants, women (n=458) and men (n=381)
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Cardiac troponin T and NT-proBNP for prediction of 30-day readmission or death in patients with acute dyspnea: Data from the Akershus Cardiac Examination 2 Study. Cardiology (IF 1.9) Pub Date : 2023-08-05 Rahul Bhatnagar,Kristian Berge,Ragnhild Røysland,Arne Didrik Høiseth,Jon Brynildsen,Geir Christensen,Torbjørn Omland,Helge Røsjø,Magnus Nakrem Lyngbakken
INTRODUCTION N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) measurements are recommended in patients with acute dyspnea. We aimed to assess the prognostic merit of cTnT compared to NT-proBNP for 30-day readmission or death in patients hospitalized with acute dyspnea. METHODS We measured cTnT and NT-proBNP within 24 hours in 314 patients hospitalized with acute dyspnea
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The biggest unmet needs in cardiovascular disease prevention in 2023. Cardiology (IF 1.9) Pub Date : 2023-08-04 Ian M Graham
1. While the major causes of atherosclerotic cardiovascular disease are known, clinical audits continue to show inadequate risk factor control, even in the highest risk subjects. 2. More effective risk estimation methods may help, and advances in this field are outlined. 3. There exist excellent Guidelines on cardiovascular disease prevention, but their very length and complexity may limit their use
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Circulating neuropeptide Y may be a biomarker for diagnosing atrial fibrillation. Cardiology (IF 1.9) Pub Date : 2023-08-04 Peng Wang,Junxia Guo,Yuhui Li,Hui Liu,Xiaohong Kang,Shuangshuang Liu,Yongchun Zhang
INTRODUCTION Sympathetic nervous system disorder promotes atrial fibrillation (AF), and neuropeptide Y (NPY) is an important neurotransmitter. This study aimed to explore the predictive value of plasma NPY in patients with AF. METHODS Five hundred seventy-six patients were divided into the AF (including paroxysmal and persistent AF; 360) and sinus rhythm (SR) groups (216). NPY level was detected using
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Effect of Meteorological Factors, Air Pollutants on Daily Hospital Admissions for Ischemic Heart Disease in Lanzhou, China. Cardiology (IF 1.9) Pub Date : 2023-07-29 Xiaoxue Meng,Jianjian Jin,Xia Han,Bing Han,Ming Bai,Zheng Zhang
BACKGROUND Meteorological factors and air pollutants are believed to be associated with cardiovascular disease. Ischemic heart disease (IHD) is a major public health issue worldwide. Few studies have investigated the associations among meteorological factors, air pollutants and IHD daily hospital admissions in Lanzhou, China. METHODS We conducted a distributed lag non-linear model (DLNM) on the basis
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Long-term trajectories of biomarkers, functional, and echocardiographic parameters in patients with chronic heart failure from dilated or ischaemic cardiomyopathy. Cardiology (IF 1.9) Pub Date : 2023-07-29 Tobias Täger,Paulina Rößmann,Norbert Frey,Bent Estler,Mirjam Mäck,Philipp Schlegel,Jan Beckendorf,Lutz Frankenstein,Hanna Fröhlich
INTRODUCTION The long-term evolution of clinical, echocardiographic and laboratory parameters of cardiac function in patients with chronic heart failure (HF) with either reduced (HFrEF) or mildly reduced (HFmrEF) left ventricular ejection fraction (LVEF) is incompletely characterized. METHODS We identified patients with chronic stable HF who presented at least twice to a university HF outpatient clinic
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Plasma Neurofilament Light Chain Is Elevated after Transcatheter Aortic Valve Implantation. Cardiology (IF 1.9) Pub Date : 2023-07-28 Karl Sjölin,Christina Christersson,Stefan James,Johan Lindbäck,Signild Åsberg,Joachim Burman
INTRODUCTION Transcatheter aortic valve implantation (TAVI) is associated with a high incidence of new silent brain infarcts (SBIs) on postprocedural neuroimaging. A venous blood sample reflecting neuronal damage following TAVI could help identify patients with potential SBIs. We aimed to investigate if a biochemical marker of neuronal injury, neurofilament light chain (NFL), is elevated after TAVI
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Validation of E/e' Using the Index-Beat Method as an Estimate of Left Atrial Pressure in Patients with Atrial Fibrillation. Cardiology (IF 1.9) Pub Date : 2023-07-28 Gaigai Ma,Ligang Fang,Xue Lin,Peng Gao,Quan Fang
INTRODUCTION Echocardiographic assessment of diastolic function during atrial fibrillation (AF) remains challenging due to the irregular cardiac cycle length. We sought to assess whether the index-beat method, the beat following two preceding cardiac cycles of equal duration, could provide a more reliable measurement of E/e' (mitral E wave/diastolic tissue Doppler velocity) than the conventional averaging
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Efficacy and Safety of Leadless Pacemaker Implantation in Octogenarians. Cardiology (IF 1.9) Pub Date : 2023-07-24 Daniel Hofer,François Regoli,Ardan M Saguner,Giulio Conte,Julius Jelisejevas,Maria Luce Caputo,Vera Graup,Lorenzo Grazioli Gauthier,Alessio Gasperetti,Jan Steffel,Angelo Auricchio,Alexander Breitenstein
INTRODUCTION Long-term complication rates in standard transvenous pacemakers are reported around 4-12% with a higher incidence in the elderly population. We report our experience in octogenarians undergoing leadless pacemaker implantation in two large-volume centers in Switzerland. METHODS Consecutive patients undergoing leadless pacemaker implantation at two Swiss large volume centers (University
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Impact of Coronary Artery Calcium Score Screening on Cardiovascular Risk Stratification of Patients with Atrial Fibrillation Undergoing Ablation. Cardiology (IF 1.9) Pub Date : 2023-07-24 Sara Fernandes,Inês Cruz,Rita Faria,João Almeida,Paulo Fonseca,Nuno Ferreira,João José Primo,Ricardo Fontes-Carvalho,Ricardo Ladeiras-Lopes
INTRODUCTION There is a well-established association between atrial fibrillation (AF) and coronary artery disease. Coronary artery calcium score (CACS) is a helpful tool to refine cardiovascular (CV) risk stratification and inform on the best strategies for primary CV prevention. This study aims to evaluate the impact of opportunistic screening with CACS on risk stratification and decision of preventive
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The effect of peridevice leaks on ischemic stroke/TIA/SE after left atrial appendage closure: A systematic review and meta-analysis. Cardiology (IF 1.9) Pub Date : 2023-07-17 Yin-Ge He,Shao-Hua Yang,Liang Xu,Yan Wang,Xu-Tan Qin,Pan-Pan Chen,Yu-Jie Zhao
BACKGROUND Left atrial appendage closure (LAAC) is a safe and effective method for preventing embolic events in patients with nonvalvular atrial fibrillation (NVAF). However, peridevice leaks (PDLs) are sometimes unavoidable. Controversy exists regarding whether PDLs lead to embolic events. OBJECTIVES This study aimed to explore the association between PDLs and embolic events, including ischaemic stroke
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Quality of Life Measures in Aortic Stenosis Research: A Narrative Review. Cardiology (IF 1.9) Pub Date : 2023-07-13 Derk Frank,Simon Kennon,Nikolaos Bonaros,Mauro Romano,Carlo Di Mario,Dirk-Jan van Ginkel,Wilbert Bor,Markus Kasel,Ole De Backer,Violetta Hachaturyan,Claudia M Lüske,Jana Kurucova,Peter Bramlage,Rima Styra
BACKGROUND Elderly patients with aortic stenosis (AS) not only have a reduced life expectancy but also a reduced quality of life (QoL). The benefits of an AS intervention may be considered a balance between a good QoL and a reasonably extended life. However, the different questionnaires being used to determine the QoL, were generally not developed for the specific situation of patients with AS and
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Prognostic Implication of Pulmonary Arterial Pressure in Surgical Repair of Predominantly Congenital Mitral Valve Regurgitation-Based Intracardiac Abnormalities. Cardiology (IF 1.9) Pub Date : 2023-07-10 Hong-Lei Zhao,Zhi-Wei Tang,Si-Qiang Zheng,Jun-Quan Chen,Yi-Fei Diao,Wei Zhang,Si-Chong Qian,Yong-Feng Shao,Sheng Zhao,Hong Liu
INTRODUCTION Knowledge is limited regarding the significance of pulmonary arterial pressure (PAP) in predominantly congenital mitral valve regurgitation (MR)-based intracardiac abnormalities. METHODS From a prospective cohort, we included 200 patients with congenital MR regardless of other associated intracardiac abnormalities (mean age 60.4 months, 67% female, systolic PAP (sPAP) 54.2 mm Hg) surgically
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A Comparative Study of Clinical and Aortic Morphological Characteristics between Bovine Aortic Arch and Normal Aortic Arch in Patients with Acute Type B Aortic Dissection. Cardiology (IF 1.9) Pub Date : 2023-06-29 Jianhua Zhang,Anxiaonan Zhang,Zhenguo Wang,Yu Sun,Xiaogang Li,Qiuyue Jin,Jinglong Shi,Jie Hou,Libo Zhang,Benqiang Yang
INTRODUCTION The purpose of this study was to analyze the difference in clinical and aortic morphological features between the bovine aortic arch and normal aortic arch in patients with acute type B aortic dissection (aTBAD). METHODS A total of 133 patients diagnosed with aTBAD were retrospectively collected. Based on aortic arch morphology, they were divided into the bovine aortic arch group (n =
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Right Heart Structure and Function after Electrical Cardioversion for Atrial Fibrillation. Cardiology (IF 1.9) Pub Date : 2023-06-27 Xiaohan Yan,Pascal B Meyre,Stefanie Aeschbacher,Matthias Bossard,Andreas Zimmermann,David Conen,Beat A Kaufmann
INTRODUCTION Atrial fibrillation (AF) adversely impacts right ventricular (RV) and right atrial (RA) structure and function. There are limited data on these changes after electrical cardioversion (ECV) and the relative contribution of heart rate to evaluate the immediate (1-2 h) and short-term (4-6 weeks) changes in right cardiac chamber dimensions and RV function after ECV in patients with persistent
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Comparison of Clinical Course and Outcomes between Dilated and Hypokinetic Non-Dilated Cardiomyopathy. Cardiology (IF 1.9) Pub Date : 2023-06-13 Ewa Dziewięcka,Mateusz Winiarczyk,Sylwia Wiśniowska-Śmiałek,Aleksandra Karabinowska-Małocha,Jan Robak,Monika Kaciczak,Filip Baranowski,Paweł Rubiś
BACKGROUND By definition, dilated cardiomyopathy (DCM) is characterized by enlargement of the left ventricular (LV) cavity, and systolic dysfunction. However, in 2016 ESC introduced a new clinical entity - hypokinetic non-dilated cardiomyopathy (HNDC). HNDC is defined as LV systolic dysfunction without LV dilatation. However, the diagnosis of HNDC has so far rarely been made by a cardiologist, and
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Cardiovascular Protection by Metformin: Latest Advances in Basic and Clinical Research. Cardiology (IF 1.9) Pub Date : 2023-06-12 Jason Z Li,Y Robert Li
BACKGROUND Metformin is among the most frequently prescribed antidiabetic drugs worldwide and remains the first-line therapy for type 2 diabetes due to its well-established glucose-lowering efficacy and favorable safety profile. SUMMARY Studies over the past decades show that metformin also exerts many other beneficial effects independent of its glucose-lowering effect both in experimental models and
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Cardiovascular Adaptations of Space Travel: A Systematic Review. Cardiology (IF 1.9) Pub Date : 2023-06-10 Shay N Sharma,Leo L T Meller,Ajay Nair Sharma,Ezra A Amsterdam
INTRODUCTION Space travel imposes significant gravitational and radiation stress on both cellular and systemic physiology, resulting in myriad cardiovascular changes that have not been fully characterized. METHODS We conducted a systematic review of the cellular and clinical adaptations of the cardiovascular system after exposure to real or simulated space travel in accordance with the Preferred Reporting
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Are the Four Pillars the Ideal Treatment for the Elderly? Cardiology (IF 1.9) Pub Date : 2023-06-08 Otilia Țica,Nicholay Teodorovich,Asgher Champsi,Moshe Swissa
This is a commentary article, there is no abstract section.
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Clinical and Pathophysiologic Insights of Free triiodothyronine/Free thyroxine Ratio in Patients with Heart Failure with Preserved Ejection Fraction: Data from the NETDiamond Cohort. Cardiology (IF 1.9) Pub Date : 2023-06-07 Ana Rita Leite,João Sérgio Neves,António Angélico-Gonçalves,Francisco Vasques-Nóvoa,Francisca A Saraiva,Inês Beatriz Pinho,Ana Cristina Oliveira,Marta Borges-Canha,Madalena von Hafe,Catarina Vale,André P Lourenço,Filipe Macedo,José Paulo Araújo,Pedro von Hafe,Jorge Almeida,João Pedro Ferreira,Adelino Leite-Moreira
BACKGROUND Thyroid dysfunction is common in patients with heart failure (HF). Impaired conversion of free T4 (FT4) into free T3 (FT3) is thought to occur in these patients, decreasing the availability of FT3 and contributing to HF progression. In HF with preserved ejection fraction (HFpEF), it is not known whether changes in conversion of thyroid hormones (THs) are associated with clinical status and
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The Influence of the Learning Curve on Clinical Outcomes in Balloon-Expandable versus Self-Expandable Transfemoral Transcatheter Aortic Valve Implantation. Cardiology (IF 1.9) Pub Date : 2023-06-06 Mihnea Istrate,Mihaela Ioana Dregoesc,Sorana D Bolboaca,Aurelia G Solomonean,Catalin Botis,Adrian Stef,Radu Hagiu,Ștefan D C Moț,Dan I Bindea,Alexandru Oprea,Cătălin A Trifan,Adrian C Iancu
INTRODUCTION Balloon-expandable (BE) and self-expandable (SE) prostheses are the main types of devices currently used in transcatheter aortic valve implantation (TAVI). Despite the different designs, clinical practice guidelines do not make any specific recommendation on the selection of one device over the other. Most operators are trained in using both BE and SE prostheses, but operator experience
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Impact of Pulmonary Hypertension Hemodynamic Phenotype on Incident Atrial Fibrillation. Cardiology (IF 1.9) Pub Date : 2023-06-05 Andrea Carolina Morales-Lara,Wiaam Elkhatib,Oludamilola Oluleye,Rashid Alhusain,Amjad Saad,Najiyah Salwa,Habeeba Siddiqui,Mikolaj A Wieczorek,Jordan Ray,Pragnesh Parikh,Charles Burger,Brian Shapiro,Fred Kusumoto,Dilip Pillai,Demilade Adedinsewo
INTRODUCTION Atrial fibrillation/flutter (AF) is common among patients with pulmonary hypertension (PH) and is associated with poor clinical outcomes. AF has been shown to occur more commonly among patients with postcapillary PH, although AF also occurs among patients with precapillary PH. The goal of this study was to evaluate the independent impact of PH hemodynamic phenotype on incident AF among
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Study on the Efficacy of Sacubitril/Valsartan in Patients with Heart Failure with Preserved Ejection Fraction Undergoing Peritoneal Dialysis. Cardiology (IF 1.9) Pub Date : 2023-05-30 Yuping Sheng,Xiaoying Ma,Ye Liu,Xingmeng Yang,Fuyun Sun
INTRODUCTION Cardiovascular disease is the most common cause of death and morbidity in patients with end-stage renal disease. Sacubitril/valsartan (SAC/VAL) can reduce the risk of cardiovascular mortality among patients with heart failure (HF). The present study set out to evaluate the efficacy of SAC/VAL in the treatment of patients with HF with preserved ejection fraction (HFpEF) undergoing peritoneal
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What Does the Late Gadolinium Enhancement on Cardiac Magnetic Resonance Imaging in COVID-19 Reflect? Cardiology (IF 1.9) Pub Date : 2023-05-25 Takahiro Okumura,Toyoaki Murohara
N/A.
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Risk Factors for Coronary Artery Aneurysm in a Chinese Pediatric Population with Kawasaki Disease at Low Risk of Intravenous Immunoglobulin Resistance: A Retrospective Cohort Study. Cardiology (IF 1.9) Pub Date : 2023-05-23 Jie Liu,Danyan Su,Piaoliu Yuan,Bingbing Ye,Suyuan Qin,Yusheng Pang
INTRODUCTION Multiple scoring systems for predicting intravenous immunoglobulin (IVIG) resistance have been developed. Although low-scoring patients with Kawasaki disease (KD) have a favorable prognosis, many develop coronary artery aneurysms (CAAs). Herein, we determined the risk factors for CAA development among patients with KD with low risk of IVIG resistance. METHODS We compared 14 scoring systems
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Hydroxychloroquine Attenuates hERG Channel by Promoting the Membrane Channel Degradation: Computational Simulation and Experimental Evidence for QT-Interval Prolongation with Hydroxychloroquine Treatment. Cardiology (IF 1.9) Pub Date : 2023-05-22 Xiqiang Wang,Yunfei Feng,Senmiao Liu,Jing Liu,Shuo Pan,Linyan Wei,Yanpeng Ma,Zhongwei Liu,Yujie Xing,Junkui Wang,Qianwei Cui,Yong Zhang,Tingzhong Wang,Chuipu Cai
INTRODUCTION The coronavirus disease 2019 (COVID-19) pandemic has led to millions of confirmed cases and deaths worldwide and has no approved therapy. Currently, more than 700 drugs are tested in the COVID-19 clinical trials, and full evaluation of their cardiotoxicity risks is in high demand. METHODS We mainly focused on hydroxychloroquine (HCQ), one of the most concerned drugs for COVID-19 therapy
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Endovascular Transcatheter Aortic Valve Replacement Outcomes in Hypertrophic Cardiomyopathy: Insights from the National Inpatient Sample (2014-2018). Cardiology (IF 1.9) Pub Date : 2023-05-13 Rohit Vyas,Salik Nazir,Keerat Rai Ahuja,Abdul Mannan Khan Minhas,Ahmed Elzanaty,Tanveer Mir,Mujeeb Sheikh
BACKGROUND Outcomes of patients with hypertrophic cardiomyopathy (HCM) following transcatheter aortic valve replacement (TAVR) remain largely unknown. OBJECTIVES This study sought to assess the clinical characteristics and outcomes of HCM patients following TAVR. METHODS We queried the National Inpatient Sample from 2014 to 2018 for TAVR hospitalizations with and without HCM, creating a propensity-matched
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Minor Myocardial Scars in Association with Cardiopulmonary Function after COVID-19. Cardiology (IF 1.9) Pub Date : 2023-05-12 Tarjei Øvrebotten,Siri Heck,Ingunn Skjørten,Gunnar Einvik,Knut Stavem,Charlotte B Ingul,Torbjørn Omland,Peder L Myhre
BACKGROUND Myocardial scars detected by cardiovascular magnetic resonance (CMR) imaging after COVID-19 have caused concerns regarding potential long-term cardiovascular consequences. OBJECTIVE The objective of this study was to investigate cardiopulmonary functioning in patients with versus without COVID-19-related myocardial scars. METHODS In this prospective cohort study, CMR was performed approximately
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Safety and Efficacy of Ticagrelor versus Clopidogrel in East Asian Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Treated with Dual Antiplatelet Therapy: A Meta-Analysis of Randomized Controlled Trials Cardiology (IF 1.9) Pub Date : 2023-04-24 Jingyuan Li, Qian Wang, Chunliu Wu, Xiaoyu Qu, Lei Zhang, Xiaofeng He, Sicong Ma, Miaohan Qiu, Xiaozeng Wang
Introduction: The treatment strategy for dual antiplatelet therapy (DAPT) with ticagrelor has been controversial in East Asian patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Our meta-analysis aimed to demonstrate whether intensified antithrombotic regimens with ticagrelor plus aspirin have more beneficial effects and fewer adverse events compared to
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Mild Tricuspid Regurgitation: A Marker of Disease Burden Independently Associated with Increased Mortality Cardiology (IF 1.9) Pub Date : 2023-04-20 Israel Gotsman, Donna R Zwas, Gabby Elbaz Greener, David Planer, Offer Amir, David Leibowitz
Background: Tricuspid regurgitation (TR) is a common finding which appears to be associated with a worse prognosis. There are conflicting data regarding the prognostic impact of mild TR. We examined the clinical characteristics and echocardiographic properties of subjects with TR and its impact on clinical outcome with particular emphasis on subjects with mild TR. Methods: Consecutive echocardiography
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Understanding Troponin as a biomarker of myocardial injury – where the path cross with cardiac imaging Cardiology (IF 1.9) Pub Date : 2023-04-18 Hafisyatul Zainal
Troponin elevation in myocardial injury are a common findings in hospitalised COVID-19 patient. Biochemistry detection of the changes are due to underlying various pathological process. The subclassification of the process require supplemental investigation particularly with cardiovascular magnetic resonance. Late gadolinium enhancement and parametric mapping offer excellent virtual tissue characterization
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Psychotropic medication-induced cardiovascular disease: adding insult to injury? Cardiology (IF 1.9) Pub Date : 2023-04-14 Nicola Marziliano, Alessandro Medoro, Sergio Davinelli, Mariano Intrieri
Not Applicable (Editorial)
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Aortic Stenosis Associated with Hypertrophic Cardiomyopathy; A double trouble Cardiology (IF 1.9) Pub Date : 2023-04-14 Eddy Barasch
Not applicable
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Haemodynamic gain index is associated with risk of sudden cardiac death and improves risk prediction: a cohort study Cardiology (IF 1.9) Pub Date : 2023-04-13 Jari Laukkanen, Nzechukwu M. Isiozor, Peter Willeit, Setor K. Kunutsor
Introduction: Haemodynamic gain index (HGI) is a novel haemodynamic parameter which can be obtained from cardiopulmonary exercise testing (CPX), but its association with sudden cardiac death (SCD) is not known. We aimed to assess the association of HGI with SCD risk in a long-term prospective cohort study. Methods: Haemodynamic gain index was calculated using heart rate and systolic blood pressure