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Neuroimmunophysiology of the Gastrointestinal Tract J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-16 Derek M. McKay, Manon Defaye, Sruthi Rajeev, Wallace K. MacNaughton, Yasmin Nasser, Keith A. Sharkey
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Biomechanical Increase in Cervical Esophageal Wall Tension during Peristalsis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-16 Ivan M. Lang, Bidyut K. Medda, Reza Shaker
During pharyngeal phase of swallowing circumferential tension of the cervical esophagus (CTE) increases caused by a biomechanical process of laryngeal elevation pulling the cervical esophagus orad. The esophagus contracts longitudinally during esophageal peristalsis, therefore, we hypothesized that CTE increases during esophageal peristalsis by a biomechanical process. Methods: We investigated this
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Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-16 Anne-Sofie H. Jensen, Henriette Ytting, Mikkel P. Werge, Elias B. Rashu, Liv E. Hetland, Mira Thing, Puria Nabilou, Johan Burisch, Kirstine N. Bojsen-Møller, Anders E. Junker, Lise Hobolth, Christian Mortensen, Flemming Tofteng, Flemming Bendtsen, Søren Møller, Mogens Vyberg, Reza R. Serizawa, Lise L. Gluud, Nicolai J. Wewer Albrechtsen
Autoimmune liver diseases are associated with an increased risk of diabetes, yet the underlying mechanisms remain unknown. In this cross-sectional study, we investigated the glucose-regulatory disturbances in patients with autoimmune hepatitis (AIH, n=19), primary biliary cholangitis (PBC, n=15), and primary sclerosing cholangitis (PSC, n=6). Healthy individuals (n=24) and patients with metabolic
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Oral tryptophan activates duodenal aryl hydrocarbon receptor in healthy subjects: a crossover randomized controlled trial J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-09 Gaston H. Rueda, Natalia Causada-Calo, Rajka Borojevic, Andrea Nardelli, Maria Ines Pinto-Sanchez, Marco Constante, Josie Libertucci, Vidhyalakshmi Mohan, Philippe Langella, Linda M. P. Loonen, Jerry M. Wells, Harry Sokol, Elena F. Verdu, Premysl Bercik
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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N-glycosylation of SCAP exacerbates hepatocellular inflammation and lipid accumulation via ACSS2-mediated histone H3K27 acetylation J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-09 Xuemei Li, Xiaoqin Tang, Yue Xiang, Zhibo Zhao, Yanping Li, Qiuying Ding, Linkun Zhang, Jingyuan Xu, Lei Zhao, Yao Chen
Sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) is a widely expressed membrane glycoprotein that acts as an important modulator of lipid metabolism and inflammatory stress. N-glycosylation of SCAP has been suggested to modulate cancer development, but its role in NASH is poorly understood. In this study, the N-glycosylation of SCAP was analyzed by using sequential
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LPA5-Dependent Signaling Regulates Regeneration of the Intestinal Epithelium Following Irradiation J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-09 Beth B. McConnell, Zhongxing Liang, Chad Xu, Yiran Han, C. Chris Yun
Lysophosphatidic acid (LPA) is a bioactive lipid molecule that regulates a wide array of cellular functions, including proliferation, differentiation, and survival, via activation of cognate receptors. The LPA5 receptor is highly expressed in the intestinal epithelium, but its function in restoring intestinal epithelial integrity following injury has not been examined. Here, we use a radiation-induced
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Milk and Lacticaseibacillus casei BL23 effects on intestinal responses in a murine model of colitis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-09 Glory Bui, Cristina Torres-Fuentes, Matteo M. Pusceddu, Melanie G. Gareau, Maria L. Marco
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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High-Energy Pacing Inhibits Slow Wave Dysrhythmias in the Small Intestine J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-09 Nipuni D. Nagahawatte, Recep Avci, Niranchan Paskaranandavadivel, Leo K. Cheng
The motility of the gastrointestinal tract is coordinated in part by rhythmic slow waves, and disrupted slow wave patterns are linked to functional motility disorders. At present, there are no treatment strategies that primarily target slow wave activity. This study assessed the use of pacing to suppress glucagon-induced slow wave dysrhythmias in the small intestine. Slow waves in the jejunum were
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StarD5 levels of expression correlate with onset and progression of steatosis and liver fibrosis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-09 Genta Kakiyama, Kei Minowa, Nanah Bai-Kamara, Taishi Hashiguchi, William M. Pandak, Daniel Rodriguez-Agudo
Background and aims: Insufficient expression of steroidogenic acute regulatory lipid transfer protein 5 (StarD5) on liver cholesterol/lipid homeostasis is not clearly defined. Methods: The ablation of StarD5 was analyzed in mice on a normal or western diet (WD) to determine its importance in hepatic lipid accumulation and fibrosis compared to wild type (WT) mice. Rescue experiments in StarD5-/- mice
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Intestinal Perfusion of Unacylated Ghrelin Alleviated Metabolic Associated Fatty Liver Disease in Rat via a Central Glucagon-Like Peptide-1 Pathway J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-02 Pengfei Lv, Hongzeng Li, Xiangbo Li, Xueyuying Wang, Jiantong Yu, Yanling Gong
Unacylated ghrelin (UAG), the unacylated form of ghrelin, accounts for 80-90% of circulation. Accumulated studies have pointed out that UAG may be used to treat metabolic disorders. This study aimed to investigate the effect of intestinal perfusion of UAG on metabolic associated fatty liver disease (MAFLD) induced by a high-fat diet and its possible mechanism. Neuronal retrograde tracking combined
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Aryl Hydrocarbon Receptor Activity in Intestinal Epithelial Cells in the Formation of Colonic Tertiary Lymphoid Tissues J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-04-02 Erika Leonor Garcia-Villatoro, Arinzechukwu Ufondu, Evelyn S. Callaway, Kimberly Allred, Stephen H. Safe, Robert S. Chapkin, Arul Jayaraman, Clinton D. Allred
After birth, the development of secondary lymphoid tissues (SLTs) in the colon is dependent on the expression of the Aryl Hydrocarbon Receptor (AhR) in immune cells as a response to the availability of AhR ligands. However, little is known about how AhR activity from intestinal epithelial cells (IECs) may influence the development of tertiary lymphoid tissues (TLTs). As organized structures that develop
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Lower uromodulin serum levels are associated with poorer prognosis in patients with cirrhosis and hepatorenal syndrome type 2 J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-19 Eva Maria Schleicher, Simon Johannes Gairing, Darko Castven, Charlotte Sophie Hock, Henrike Dobbermann, Sophia Heinrich, Myriam Meineck, Leonard Kaps, Peter Robert Galle, Julia Weinmann-Menke, Marc Nguyen-Tat, Jens Uwe Marquardt, Christian Labenz
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii served as key components of fecal microbiota transplantation to alleviate colitis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-19 Binqiang Xu, Yang Fu, Nuoming Yin, Wenfei Qin, Zehua Huang, Wei Xiao, Huizhen Huang, Qixiang Mei, Junjie Fan, Yue Zeng, Chunlan Huang
Fecal microbiota transplantation (FMT) is a promising therapy for inflammatory bowel disease (IBD) via rectifying gut microbiota. The aim of this study was to identify a mechanism of how specific bacteria-associated immune response contributes to alleviated colitis. 40 donors were divided into high (donor-H) and low (donor-L) groups according to diversity and the abundance of Bacteroides and Faecalibacterium
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Albumin promoter-driven FlpO expression induces efficient genetic recombination in mouse liver J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-12 Xiaohui Zhu, Yan Yang, Dongfeng Feng, Oliver Wang, Jiaxiang Chen, Jiale Wang, Bin Wang, Yang Liu, Brandy H. Edenfield, Ashley N. Haddock, Ying Wang, Tushar Patel, Yan Bi, Baoan Ji
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-12 Brooke M. Bullard, Sierra J. McDonald, Thomas D. Cardaci, Brandon N. VanderVeen, Ahmed D. Mohammed, Jason L. Kubinak, Joseph F. Pierre, Ioulia Chatzistamou, Daping Fan, Lorne J. Hofseth, E. Angela Murphy
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Protease-activated receptor 2 drives migration in a colon cancer cell line but not in non-cancerous human epithelial cells J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-05 Larissa Lucena Périco, Andrew J. Vegso, Cristiane H. Baggio, Wallace K. MacNaughton
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Interaction between fatty acid oxidation and ethanol metabolism in liver J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-05 Yongke Lu, Joseph George
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Hepatic LGR4 aggravates cholestasis-induced liver injury in mice J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-03-05 Yuan Gao, Wenbo Zhai, Lijun Sun, Xueqian Du, Xianfeng Wang, Michael W. Mulholland, Yue Yin, Weizhen Zhang
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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A simple and effective genotyping workflow for rapid detection of CRISPR genome editing J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-02-27 Lingxiang Wang, Jiale Wang, Dongfeng Feng, Bin Wang, Yasmin Jahan-mihan, Ying Wang, Yan Bi, Do Young Lim, Baoan Ji
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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The Effects of Corticotropin-Releasing Hormone on Gastric Electrical Activity and Sensorimotor Function in Healthy Volunteers: A Double-blinded Crossover Study J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-02-20 I-Hsuan Huang, Jolien Schol, Stefan Calder, Armen A. Gharibans, Karen Van den Houte, Annelies Verheyden, Bert Broeders, Florencia Carbone, Gregory O'Grady, Jan Tack
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Lipidomic signatures discriminate subtle hepatic changes in the progression of porcine non-alcoholic steatohepatitis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-02-20 Luis V. Herrera-Marcos, Roberto Martínez-Beamonte, Carmen Arnal, Cristina Barranquero, Juan J. Puente-Lanzarote, José M. Lou-Bonafonte, Gonzalo Gonzalo-Romeo, Gabriele Mocciaro, Benjamin Jenkins, Joaquin C. Surra, María J. Rodríguez-Yoldi, Víctor Alastrué-Vera, Jesús Letosa, Agustín García-Gil, Antonio Güemes, Albert Koulman, Jesús Osada
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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A Mathematical Model of ENaC and Slc26a6 Regulation by CFTR in Salivary Gland Ducts J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-02-13 Shan Su, Amanda Wahl, John Rugis, Vinod Suresh, David Yule, James Sneyd
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Mechanisms Driving Fasting-Induced Protection from Genotoxic Injury in the Small Intestine J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-02-13 Kali Deans-Fielder, Timothy Wu, Thanh Nguyen, Sarah To, Yang-Zhe Huang, Steven J. Bark, Jason C. Mills, Noah F. Shroyer
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Role of mechanoregulation in mast cell-mediated immune inflammation of the smooth muscle in pathophysiology of esophageal motility disorders J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-31 Raj K Goyal, Satish Rattan
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Blueberry anthocyanins improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7 to affect ferroptosis of hepatic stellate cells. J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-31 Likun Liu, Jinhui Du, Haiqing Fan, Yue Yu, Yilin Luo, Fang Gu, Hui Yu, Xin Liao
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Gastrointestinal dysmotility in rodent models of Parkinson's disease J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-23 Carolina Pellegrini, R. Alberto Travagli
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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NADPH oxidase 1 promotes hepatic steatosis in obese mice and is abrogated by augmented skeletal muscle mass J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-23 Sebastian Larion, Caleb A. Padgett, James D. Mintz, Jennifer A. Thompson, Joshua T. Butcher, Eric J. Belin de Chantemèle, Stephen Haigh, Sandeep Khurana, David J. Fulton, David W. Stepp
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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A functional interplay between the two BMP-SMAD pathway inhibitors TMPRSS6 and FKBP12 regulates hepcidin expression in vivo J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-22 Mariateresa Pettinato, Mariam Aghajan, Shuling Guo, Letizia Bavuso Volpe, Rossana Carleo, Antonella Nai, Alessia Pagani, Sandro Altamura, Laura Silvestri
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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NHE3 inhibitor tenapanor maintains intestinal barrier function, decreases visceral hypersensitivity, and attenuates TRPV1 signaling in colonic sensory neurons J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-22 Andrew J. King, Lin Chang, Qian Li, Liansheng Liu, Yaohui Zhu, Pankaj J. Pasricha, Ji Wang, Matthew Siegel, Jeremy S. Caldwell, Susan Edelstein, David P. Rosenbaum, Kenji Kozuka
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Implicating the Cholecystokinin B Receptor in Liver Stem Cell Oncogenesis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-22 Martha D. Gay, Jack C. Drda, Wenqiang Chen, Yimeng Huang, Amal A. Yassin, Tetyana Duka, Hongbin Fang, Narayan Shivapurkar, Jill P. Smith
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Inhibition of visceral adipose tissue-derived pathogenic signals by activation of adenosine A2AR improves hepatic and cardiac dysfunction of NASH mice J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-22 Chia-Chang Huang, Hsiao-Yun Yeh, Roger Lin, Tsai-Ling Liao, Hsiao-Chin Shen, Ying-Ying Yang, Han-Chieh Lin
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Characterisation of Mitochondria-associated ER membranes in the enteric nervous system under physiological and pathological conditions J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-16 Giada Delfino, Jean Baptiste Briand, Thibauld Oullier, Léa Nienkemper, Jenny Greig, Joëlle Véziers, Michel Neunlist, Pascal Derkinderen, Sebastien Paillusson
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Short-term and long-term effects of unilateral external carotid artery ligation on orofacial functions in rats J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-16 Titi Chotirungsan, Yuhei Tsutsui, Nobuaki Saka, Satomi Kawada, Nozomi Dewa, Jin Magara, Takanori Tsujimura, Makoto Inoue
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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A ganglionic intestino-intestinal reflex activated by acute noxious challenge J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-16 Martin J. Stebbing, Anthony D. Shafton, Catherine E. Davey, Madeleine R. DiNatale, John B. Furness, Robin M. McAllen
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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GSK3β/NF-κB dependent transcriptional regulation of homeostatic hepatocyte Tnf production J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Maya R. Grayck, William C. McCarthy, Mack Solar, Emma Golden, Natarajan Balasubramaniyan, Lijun Zheng, Laura G. Sherlock, Clyde J. Wright
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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An inulin-type fructan CP-A from Codonopsis pilosula alleviates TNBS-induced ulcerative colitis based on serum-untargeted metabolomics J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Jiangtao Zhou, Jiajing Wang, Deyun Li, Zhijia Zhang, Changjian Wang, Xuepeng Zhang, Xiexin Xu, Jianping Gao
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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FOXO3: at the crossroads of metabolic, inflammatory, and tumorigenic remodeling in the colon J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Patricia Snarski, Jenisha Ghimire, Suzana D Savkovic
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Morphological, molecular, and functional characterization of mouse glutamatergic myenteric neurons J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Jia Liu, Shaopeng Zhang, Sharareh Emadi, Tiantian Guo, Longtu Chen, Bin Feng
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Improving morphological and functional properties of enteric neuronal networks in vitro using a novel upside-down culture approach J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Steven Schulte, Dominique Decker, Bharat Nowduri, Manuela Gries, Anne Christmann, Antoine Meyszner, Holger Rabe, Monika Saumer, Karl Herbert Schäfer
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Highlights of how single cell analyses are illuminating differentiation and disease in the gastric corpus J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Mahliyah Adkins-Threats, Yang-Zhe Huang, Jason Mills
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Comparison of etiologic and physiologic characteristics of fecal incontinence in men and women. J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Reuma Margalit-Yehuda, Carla Maradey-Romero, Yana Davidov, Edward Ram, Dan Carter
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Alterations in gene expression and microbiome composition upon calcium sensing receptor deletion in the mouse esophagus J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Solange M. Abdulnour-Nakhoul, Jay K. Kolls, Eric K. Flemington, Nathan A. Ungerleider, Hani N. Nakhoul, Kejing Song, Nazih L. Nakhoul
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Experimental colitis-induced visceral hypersensitivity is attenuated by GABA-treatment in mice J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2024-01-09 Michael S. Gold, Emanuel Loeza-Alcocer
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Enteric Glial Cell Network Function is Required for Epithelial Barrier Restitution following Intestinal Ischemic Injury in the Early Postnatal Period J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-12-26 Amanda L. Ziegler, Madison L. Caldwell, Sara J. Erwin, Emily A. Hellstrom, Anastasia E. Sheridan, Melissa S. Touvron, Tiffany A. Pridgen, Scott T. Magness, Jack Odle, Laurianne Van Landeghem, Anthony T. Blikslager
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Adiponectin affects ileal contractility of mouse preparations J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-12-19 Eglantina Idrizaj, Silvia Nistri, Patrizia Nardini, Maria Caterina Baccari
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Alterations in descending brain-spinal pathways regulating colorectal motility in a rat model of Parkinson's disease J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-12-19 Tomoya Sawamura, Natsufu Yuki, Kanae Aoki, Kazuhiro Horii, Yuuki Horii, Kiyotada Naitou, Shumpei Tsukamoto, Takahiko Shiina, Yasutake Shimizu
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Expression and function of transient receptor potential melastatin 3 in the spinal afferent innervation of the mouse colon J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-12-12 James W. King, Aidan S. W. Bennett, Hannah M. Wood, Corey C. Baker, Hanin Alsaadi, Max Topley, Stephen A. Vanner, David E. Reed, Alan E. Lomax
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Sex differences in zymosan-induced behavioral visceral hypersensitivity and colorectal afferent sensitization J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-12-05 Tiantian Guo, Jia Liu, Longtu Chen, Zichao Bian, Guoan Zheng, Bin Feng
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Repurposing dried blood spot (DBS) device technology to examine bile acid profiles in human dried fecal spot (DFS) samples J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-28 Melinda A. Engevik, Santosh Thapa, Ian Lillie, Mary Beth Yacyshyn, Bruce Yacyshyn, Andrew J. Percy, Donald Chace, Thomas D. Horvath
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Seladelpar combined with complementary therapies improves fibrosis, inflammation and liver injury in a mouse model of nonalcoholic steatohepatitis J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-28 Yun-Jung Choi, Jeffrey D. Johnson, Jin-Ju Lee, Jiangao Song, Marcy Matthews, Marc K. Hellerstein, Charles A. McWherter
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Propionibacterium freudenreichii CIRM-BIA 129 mitigates colitis through S layer protein B-dependent epithelial strengthening J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-21 Marine Mantel, Tony Durand, Anne Bessard, Ségolène Pernet, Julie Beaudeau, Juliana Guimaraes-Laguna, Marie-Bernadette Maillard, Eric Guédon, Michel Neunlist, Yves Le-Loir, Gwenaël Jan, Malvyne Rolli-Derkinderen
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Characterization of neuromuscular transmission and projections of muscle motor neurons in the rat stomach J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-21 Madeleine R. Di Natale, Billie Hunne, Martin J. Stebbing, Xiaokai Wang, Zhongming Liu, John B. Furness
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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The distribution of purinergic receptors, P2Y and P2X, expression within the intestine J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-21 Kristen A. Engevik, Francesca J. Scribano, J. Thomas Gebert, Jacob L. Perry, Sue E. Crawford, Joseph M. Hyser
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Defining a timeline of colon pathologies after keratin 8 loss: Rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-14 Maria A. Ilomäki, Lauri Polari, Carl-Gustaf A. Stenvall, Mina Tayyab, Kirah Kähärä, Karen M. Ridge, Diana M. Toivola
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Intestinal ultrasound, an underutilized tool for assessing colonic motility J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-14 Gabrio Bassotti, Giovanni Maconi
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Cholestenoic Acid as Endogenous Epigenetic Regulator Decreases Hepatocyte Lipid Accumulation in Vitro and in Vivo J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-14 Yaping Wang, William M. Pandak, Phillip B. Hylemon, Hae-Ki Min, John Min, Michael Fuchs, Arun J. Sanyal, Shunlin Ren
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Disruption of hypoxia inducible factor-2α in neutrophils decreases colitis-associated colon cancer J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-07 Rashi Singhal, Nikhil Kumar Kotla, Sumeet Solanki, Wesley Huang, Hannah N. Bell, Marwa O. Elderany, Cristina Castillo, Yatrik M. Shah
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Th2 Cytokine Signaling through IL-4Rα Increases Eotaxin-3 Secretion and Tension in Human Esophageal Smooth Muscle J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-07 Melissa R. Nelson, Xi Zhang, Eitan Podgaetz, Xuan Wang, Qiuyang Zhang, Zui Pan, Stuart Jon Spechler, Rhonda F. Souza
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium dependent bile acid transporter J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-11-07 Christine M. Calton, Katelyn Carothers, Shylaja Ramamurthy, Neha Jagadish, Bhumika Phanindra, Anett Garcia, V.K. Viswanathan, Melissa D. Halpern
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.
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Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfα expression, gut barrier dysfunction, and endotoxemia in mice J. Appl. Physiol. Gastrointest. Liver Physiol. (IF 4.5) Pub Date : 2023-10-24 Meli'sa S. Crawford, Arzu Ulu, Brianna M. Ramirez, Alina N. Santos, Pritha Chatterjee, Vinicius Canale, Salomon Manz, Hillmin Lei, Tara M. Nordgren, Declan F. McCole
American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.