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Redundancy effect of initial enactment encoding and subsequent testing on memory enhancement: Insights from an electrophysiological study Brain Res. (IF 2.9) Pub Date : 2024-04-14 Xiaoyu Cui, Jing Lu, Yi Liu, Juan Li, Zhiwei Zheng, Chunyan Guo
Testing is more beneficial for memory retention than restudying the same content. However, the effect of the initial encoding method on the testing effect remains unclear. In this study, a classical testing effect paradigm was employed, along with event-related potentials (ERP), to investigate the electrophysiological processes underlying the effect of enactment encoding on the testing effect. Participants
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Association of impulsive behavior and cerebrospinal fluid/plasma oxidation and antioxidation ratio in Chinese men Brain Res. (IF 2.9) Pub Date : 2024-04-11 Xiaoning Jiang, Xiaoli Han, Tiantian Kong, Yan Wu, Ligang Shan, Zhuqing Yang, Yanlong Liu, Fan Wang
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Effects of sleep deprivation on anxiety-depressive-like behavior and neuroinflammation Brain Res. (IF 2.9) Pub Date : 2024-04-10 Dandan Cao, Yi Zhao, Yuting Wang, Dongyun Wei, Minhao Yan, Shijie Su, Huashan Pan, Qi Wang
Depression is defined by a persistent low mood and disruptions in sleep patterns, with the WHO forecasting that major depression will rank as the third most prevalent contributor to the global burden of disease by the year 2030. Sleep deprivation serves as a stressor that triggers inflammation within the central nervous system, a process known as neuroinflammation. This inflammatory response plays
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Implicit and explicit motor imagery ability after SCI: Moving the elbow makes the difference Brain Res. (IF 2.9) Pub Date : 2024-04-10 Sébastien Mateo, Aymeric Guillot, Sonia Henkous, Anthony Gelis, Sébastien Daligault, Gilles Rode, Christian Collet, Franck Di Rienzo
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Disruption of sphingomyelin synthase 2 gene alleviates cognitive impairment in a mouse model of Alzheimer’s disease Brain Res. (IF 2.9) Pub Date : 2024-04-10 Osamu Uchiumi, Jingyu Zou, Sachiko Yamaki, Yoshie Hori, Munenori Ono, Ryo Yamamoto, Nobuo Kato
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Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota Brain Res. (IF 2.9) Pub Date : 2024-04-10 Lu Han, Weijia Chen, Jianming Li, Yan Zhao, Ying Zong, Zhongmei He, Rui Du
Alzheimer’s disease (AD) is a primary degenerative encephalopathy that first appeared as a decline in memory and learning skills. Over time, the condition's severity grew. Palmatine (Pal) alleviates Alzheimer's disease symptoms, which has neuroprotective benefits. Numerous investigations have demonstrated a close relationship among AD and gut structure changes. The aim of the research was investigating
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Function and mechanism exploring of icariin in schizophrenia through network pharmacology Brain Res. (IF 2.9) Pub Date : 2024-04-09 Bing Liu, Chengqiang Wang, Ruyuan Liu, Weilai Xiang, Chang Yang, Di Li
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Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice Brain Res. (IF 2.9) Pub Date : 2024-04-09 Lu Liu, Jie Wu, Changlin Zhang, Tong Cao, Yongli Lu, Zhi He, Zicheng Li
The anxiety caused by morphine protracted abstinence is considered to be an important factor contributes to drug-seeking and relapse. Endoplasmic reticulum (ER) stress plays important roles in many kinds of mental disorders including drug addiction and anxiety, but it is unclear whether ER stress is involved in anxiety-like behaviors induced by morphine withdrawal. In this study, by using behavioral
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Manipulation of α4βδ GABAA receptors alters synaptic pruning in layer 3 prelimbic prefrontal cortex and impairs temporal order recognition: Implications for schizophrenia and autism Brain Res. (IF 2.9) Pub Date : 2024-04-08 Sheryl S Smith, Safae Benanni, Quiana Jones, Lindsay Kenney, Matthew R. Evrard
Temporal order memory is impaired in autism spectrum disorder (ASD) and schizophrenia (SCZ). These disorders, more prevalent in males, result in abnormal dendritic spine pruning during adolescence in layer 3 (L3) medial prefrontal cortex (mPFC), yielding either too many (ASD) or too few (SCZ) spines. Here we tested whether altering spine density in neural circuits including the mPFC could be associated
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Targeting VDAC: A potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease Brain Res. (IF 2.9) Pub Date : 2024-04-08 Yaqian Yang, Xiaotao Jia, Xinmao Yang, Jie Wang, Yan Fang, Xiaoping Ying, Meiqian Zhang, Jing Wei, Yanfang Pan
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Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats Brain Res. (IF 2.9) Pub Date : 2024-04-06 Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo Li
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M1-type microglia-derived exosomes contribute to blood–brain barrier damage Brain Res. (IF 2.9) Pub Date : 2024-04-06 Wen Jiang, Yan Wu, Ailan Pang, Peiyao Li, Song Mei
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Temporal expression of brainstem neurotrophic proteins following mild traumatic brain injury Brain Res. (IF 2.9) Pub Date : 2024-04-04 Jacob I. McPherson, Vijaya Prakash Krishnan Muthaiah, Kathiravan Kaliyappan, John J. Leddy, Kirkwood E. Personius
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Alkaloids as drug leads in Alzheimer's treatment: Mechanistic and therapeutic insights Brain Res. (IF 2.9) Pub Date : 2024-04-04 Md. Rezaul Islam, Shopnil Akash, Mohammed Murshedul Islam, Nadia Sarkar, Ajoy Kumer, Sandip Chakraborty, Kuldeep Dhama, Majed Ahmed Al-Shaeri, Yasir Anwar, Polrat Wilairatana, Abdur Rauf, Ibrahim F. Halawani, Fuad M. Alzahrani, Haroon Khan
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Spinal bestrophin-1 and anoctamin-1 channels have a pronociceptive role in the tactile allodynia induced by REM sleep deprivation in rats Brain Res. (IF 2.9) Pub Date : 2024-04-04 Carlos J. Martínez-Magaña, Paulina A. Muñoz-Castillo, Janet Murbartián
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Edaravone dexborneol attenuates cognitive impairment in a rat model of vascular dementia by inhibiting hippocampal oxidative stress and inflammatory responses and modulating the NMDA receptor signaling pathway Brain Res. (IF 2.9) Pub Date : 2024-04-04 Hui Guo, Haodong Li, Zhisheng Jia, Shuyu Ma, Jin Zhang
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Role of electrophysiological activity and interactions of lateral habenula in the development of depression-like behavior in a chronic restraint stress model Brain Res. (IF 2.9) Pub Date : 2024-04-03 Chang Wang, Yuting Sun, Yanjie Xing, Kezhou Liu, Kedi Xu
Closed-loop deep brain stimulation (DBS) system offers a promising approach for treatment-resistant depression, but identifying universally accepted electrophysiological biomarkers for closed-loop DBS systems targeting depression is challenging. There is growing evidence suggesting a strong association between the lateral habenula (LHb) and depression. Here, we took LHb as a key target, utilizing multi-site
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Neurobehavioral and molecular changes in a rodent model of ACTH-induced HPA axis dysfunction Brain Res. (IF 2.9) Pub Date : 2024-04-03 Farhanah N Sallie, Leandrie Pienaar, Andrea Lubbe, Sanelisiwe Xhakaza, Srinivasa R Manne, Beatriz G. de la Torre, Fernando Albericio, William MU Daniels, Aletta ME Millen, Sooraj Baijnath
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Transcriptomic insights into multiple system atrophy from a PLP-α-synuclein transgenic mouse model Brain Res. (IF 2.9) Pub Date : 2024-04-03 L. Nicholson, I.S. Piras, M.D. DeBoth, A. Siniard, A. Heras-Garvin, N. Stefanova, M.J. Huentelman
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Neuritin promotes autophagic flux by inhibiting the cGAS-STING pathway to alleviate brain injury after subarachnoid haemorrhage Brain Res. (IF 2.9) Pub Date : 2024-04-01 Hao Zhang, Kunhao Ren, Youjie Hu, Bin Liu, Yaowen He, Hui Xu, Ketao Ma, Weidong Tian, Linzhi Dai, Dong Zhao
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Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury Brain Res. (IF 2.9) Pub Date : 2024-04-01 Tianqi Zhao, Yuxin Zhou, Dabing Zhang, Dong Han, Jingyuan Ma, Shanshan Li, Ting Li, Shuqun Hu, Zhouru Li
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Aurothioglucose encapsulated nanoparticles fostered neuroprotection in streptozotocin-induced Alzheimer’s disease Brain Res. (IF 2.9) Pub Date : 2024-04-01 Shiv Kumar Kushawaha, Mahendra Singh Ashawat, Divya Soni, Puneet Kumar, Rimpi, Ashish Baldi
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Exploring the potential of quercetin in Alzheimer's Disease: Pharmacodynamics, Pharmacokinetics, and Nanodelivery systems Brain Res. (IF 2.9) Pub Date : 2024-03-31 Komaldeep Kaur, Yogesh A. Kulkarni, Sarika Wairkar
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Abnormal multisensory temporal discrimination in Parkinson’s disease Brain Res. (IF 2.9) Pub Date : 2024-03-30 Zahra Rostami, Mehri Salari, Sara Mahdavi, Masoud Etemadifar
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1-(Phenylselanyl)-2-(p-tolyl)indolizine: A selenoindolizine with potential antidepressant-like activity in mice mediated by the modulation of dopaminergic and noradrenergic systems Brain Res. (IF 2.9) Pub Date : 2024-03-30 Marcia Juciele da Rocha, Marcelo Heinemann Presa, Gustavo D'Avila Nunes, Narryman Pinto Zuge, Camila Simões Pires, Evelyn Mianes Besckow, Caroline Signorini Gomes, Luiz Henrique Dapper, Eder João Lenardão, Filipe Penteado, Cristiani Folharini Bortolatto, César Augusto Brüning
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Behavioral and neural measures of semantic conflict monitoring: Findings from a novel picture-word interference task Brain Res. (IF 2.9) Pub Date : 2024-03-29 Elizabeth A. Lydon, Holly B. Panfil, Sharbel Yako, Raksha A. Mudar
Conflict monitoring has been studied extensively using experimental paradigms that manipulate perceptual dimensions of stimuli and responses. The picture-word interference (PWI) task has historically been used to examine semantic conflict, but primarily for the purpose of examining lexical retrieval. In this study, we utilized two novel PWI tasks to assess conflict monitoring in the context of semantic
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The partial upward migration of the laryngeal motor cortex: A window to the human brain evolution Brain Res. (IF 2.9) Pub Date : 2024-03-28 Abbas Taheri
The pioneer cortical electrical stimulation studies of the last century did not explicitly mark the location of the human laryngeal motor cortex (LMC), but only the “vocalization area” in the lower half of the lateral motor cortex. In the final years of 2010́s, neuroimaging studies did demonstrate two human cortical laryngeal representations, located at the opposing ends of the orofacial motor zone
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Localized alterations in cortical thickness and sulcal depth of the cingulo-opercular network in relation to lower reading fluency skills in children with dyslexia Brain Res. (IF 2.9) Pub Date : 2024-03-28 Tzipi Horowitz-Kraus, Jonathan Dudley, Keri Rosch, Jenny Fotang, Rola Farah
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Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated parkinsonism in rats: Modulation of dopamine D3 receptor Brain Res. (IF 2.9) Pub Date : 2024-03-28 Heba M. Mansour, Ahmed F. Mohamed, Mahmoud. M. Khattab, Aiman S. El-Khatib
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Upregulation of NADPH-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: Development of sporadic Alzheimer’s disease Brain Res. (IF 2.9) Pub Date : 2024-03-27 Mubeen A. Ansari, Aishah Al-Jarallah, Muddanna S. Rao, Ahmed Babiker, Khaled Bensalamah
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The biological efficacy of Apelin against focal transient cerebral ischemia–reperfusion injury. A systematic review and meta-analysis of animal studies Brain Res. (IF 2.9) Pub Date : 2024-03-27 Sedigheh Behrouzifar, Habibollah Esmaily
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A Disintegrin And Metalloprotease 10 expression within the murine central nervous system Brain Res. (IF 2.9) Pub Date : 2024-03-26 Aïda Padilla-Ferrer, Alex Carrete, Anne Simon, Delphine Meffre, Mehrnaz Jafarian-Tehrani
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IL-6 mediates olfactory dysfunction in a mouse model of allergic rhinitis Brain Res. (IF 2.9) Pub Date : 2024-03-24 Xiao-Yu Song, Qi Sun, Shi-Zhuang Wei, Han-Rui Wang, Yao Wang, Wen-Bin Zhang, Chao Ren, Xi-Cheng Song, Ya-Kui Mou
Immune-inflammatory response is a key element in the occurrence and development of olfactory dysfunction (OD) in patients with allergic rhinitis (AR). As one of the core factors in immune-inflammatory responses, interleukin (IL)-6 is closely related to the pathogenesis of allergic diseases. It may also play an important role in OD induced by diseases, such as Sjögren’s syndrome and coronavirus disease
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Exploring the neuroprotective role of physical activity in cerebral small vessel disease Brain Res. (IF 2.9) Pub Date : 2024-03-23 Maria E. Anderson, Eleanor J. Wind, Lisa S. Robison
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Myeloperoxidase to high-density lipoprotein ratio: Potential predictor of severity and outcome in patients with acute ischemic stroke Brain Res. (IF 2.9) Pub Date : 2024-03-21 Penghong Li, Cailang Niu, Xueqing Du, Mina Zhao, Haobo Wang, Debo Yang, Yuan Li, Wei Jing
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Neuropsychiatric symptoms profile and markers of Alzheimer disease–type pathology in patients with Lewy body dementias Brain Res. (IF 2.9) Pub Date : 2024-03-21 Chaofan Geng, Leilei Tan, Chen Chen
To determine whether Lewy body dementia (LBD) patients with likely copathology of Alzheimer’s disease (AD) exhibit greater neuropsychiatric symptom (NPS) compared to those without likely AD-type copathology. We enrolled 69 individuals diagnosed with Lewy body dementia (LBD), comprising both dementia with Lewy bodies (DLB) (n = 36) and Parkinson's disease dementia (PDD) (n = 33). These participants
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Diagnosing schizophrenia using deep learning: Novel interpretation approaches and multi-site validation Brain Res. (IF 2.9) Pub Date : 2024-03-20 Tingting Weng, Yuemei Zheng, Yingying Xie, Wen Qin, Li Guo
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Age-related changes in meningeal lymphatic function are closely associated with vascular endothelial growth factor-C expression Brain Res. (IF 2.9) Pub Date : 2024-03-20 Qi Liu, Cheng Wu, Qian Ding, Xiang-yu Liu, Ni Zhang, Jun-hui Shen, Zi-tong Ou, Tuo Lin, Hong-xiang Zhu, Yue Lan, Guang-qing Xu
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Towards understanding sex differences in autism spectrum disorders Brain Res. (IF 2.9) Pub Date : 2024-03-19 Karen Q. Leow, Mary A. Tonta, Jing Lu, Harold A. Coleman, Helena C. Parkington
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Variants in 3p24.3 predicts the risk of early neurological deterioration in large artery atherosclerotic stroke Brain Res. (IF 2.9) Pub Date : 2024-03-16 Xiaoya Huang, Qiang Ye, Zhenguo Zhu, Yanyan Chen, Niange Xia, Rongrong Chen, Wujun Geng, Zusen Ye
The rate of early neurological deterioration (END) differs in different subtypes of ischaemic stroke. Previous studies showed gene is a novel susceptibility locus for the occurrence of atherosclerosis and thrombotic events. The objective of this research is to examine the efficacy that may have on the risk of END in large artery atherosclerotic (LAA) stroke. Tagged single nucleotide polymorphisms (SNPs)
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Mu-ERD reflects action understanding, but the effect is small Brain Res. (IF 2.9) Pub Date : 2024-03-16 Lawrence Paul Behmer Jr.
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Adora2A downregulation promotes caffeine neuroprotective effect against LPS-induced neuroinflammation in the hippocampus Brain Res. (IF 2.9) Pub Date : 2024-03-15 Paula Lemes dos Santos Sanna, Liebert Bernardes Carvalho, Camila Cristina dos Santos Afonso, Kassia de Carvalho, Rogério Aires, Jennyffer Souza, Marcel Rodrigues Ferreira, Alexander Birbrair, Maria Martha Bernardi, Alexandra Latini, Rodrigo A. Foganholi da Silva
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The relationship between oxidative stress markers and 1H-Magnetic resonance spectroscopy findings in obsessive compulsive disorder Brain Res. (IF 2.9) Pub Date : 2024-03-15 Fatma Subaşı Turgut, Mahmut Bulut, Salih Hattapoğlu, Mehmet Güneş, Mehmet Cemal Kaya, Faysal Ekici, Mehmet Guli Çetinçakmak, İbrahim Kaplan, Murad Atmaca
The purpose of this study was to examine N-acetyl aspartate (NAA)/creatine (Cr) and glutamate, glutamine, and gamma-aminobutyric acid complex (Glx)/Cr levels in patients with obsessive compulsive disorder (OCD) and healthy controls’ orbitofrontal cortex (OFC) and caudate nucleus (CN) by proton magnetic resonance spectroscopy (1H-MRS) method and to investigate their relationship with oxidative stress
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Poly(rC)-binding protein 1 alleviates neurotoxicity in 6-OHDA-induced SH-SY5Y cells and modulates glial cells in neuroinflammation Brain Res. (IF 2.9) Pub Date : 2024-03-14 Ling-Yun Ma, Bingbing Jia, Haoming Geng, Jiantao Liang, Lirong Huo
Parkinson's disease (PD) is a debilitating neurodegenerative condition characterized by the loss of dopaminergic neurons and neuroinflammation. Previous research has identified the involvement of Poly (rC)-binding protein 1 (PCBP1) in certain degenerative diseases; however, its specific mechanisms in PD remain incompletely understood. In this study, 6-OHDA-induced neurotoxicity in the cell lines SH-SY5Y
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Corrigendum to “Potential biomaterials and experimental animal models for inventing new drug delivery approaches in the neurodegenerative disorder: Multiple sclerosis” [Brain Res. 1822 (2023) 148674] Brain Res. (IF 2.9) Pub Date : 2024-03-14 Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Sruthi Sarvepalli, Chandrakant R. Kokare
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LPCAT3 exacerbates early brain injury and ferroptosis after subarachnoid hemorrhage in rats Brain Res. (IF 2.9) Pub Date : 2024-03-12 Jiahui Hao, Tong Wang, Cheng Cao, Xiang Li, Haiying Li, Heng Gao, Jinquan Li, Haitao Shen, Gang Chen
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Dynamic monitoring of radiation-induced white matter microstructure injury in nasopharyngeal carcinoma via high-angular resolution diffusion imaging Brain Res. (IF 2.9) Pub Date : 2024-03-11 Tiansheng Li, Yihao Guo, Xin Jin, Tao Liu, Gang Wu, Weiyuan Huang, Feng Chen
To investigate white matter microstructural abnormalities caused by radiotherapy in nasopharyngeal carcinoma (NPC) patients using MRI high-angular resolution diffusion imaging (HARDI). We included 127 patients with pathologically confirmed NPC: 36 in the pre-radiotherapy group, 29 in the acute response period (post-RT-AP), 23 in the early delayed period (post-RT-ED) group, and 39 in the late-delayed
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Microstructural abnormality of white matter tracts in rheumatoid arthritis Brain Res. (IF 2.9) Pub Date : 2024-03-11 Zeyu Liu, Bo Hou, Hui You, Chen Yu, Xinping Tian, Mengtao Li, Xiaofeng Zeng, Qian Wang, Feng Feng
Structural and functional brain imaging studies have reported abnormalities of gray matter morphology and functional activities in patients with rheumatoid arthritis (RA). However, it is largely unknown whether patients with RA show alterations of white matter microstructural organization. To automatically identify alteration of white matter microstructure in patients with RA and further examine how
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Ligation of cervical lymphatic vessels decelerates blood clearance and worsens outcomes after experimental subarachnoid hemorrhage Brain Res. (IF 2.9) Pub Date : 2024-03-11 Shi-Qiao Luo, Sheng-Qing Gao, Mao-Xing Fei, Xue-Wang, Yan-Sun, Ran-Zhao, Yan-Ling Han, Han-Dong Wang, Meng-Liang Zhou
Subarachnoid hemorrhage (SAH) is characterized by the extravasation of blood into the subarachnoid space, in which erythrocyte lysis is the primary contributor to cell death and brain injuries. New evidence has indicated that meningeal lymphatic vessels (mLVs) are essential in guiding fluid and macromolecular waste from cerebrospinal fluid (CSF) into deep cervical lymph nodes (dCLNs). However, the
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Symmetric unipedal balance in quiet stance and dynamic tasks in older individuals Brain Res. (IF 2.9) Pub Date : 2024-03-07 Paola Janeiro Valenciano, Victória Emiliano Castan, Pedro Henrique Martins Monteiro, Luis Augusto Teixeira
Previous evidence of increased difference of muscular strength between the dominant and non-dominant legs in older adults suggests the possibility of dissimilar balance control between the legs (between-leg asymmetry) associated with aging. In the current investigation, we evaluated between-leg asymmetries in older adults when performing quiet and dynamic balance tasks. Fifty-two physically active
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Children’s early signs and developmental trajectories of psychotic-like experiences Brain Res. (IF 2.9) Pub Date : 2024-03-06 Luxia Jia, Ziqian Wei, Juan Wang, Xuan Zhang, Huagen Wang, Runsen Chen, Xiaoqian Zhang
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Cerebral endothelial cells mediated enhancement of brain pericyte number and migration in oxygen-glucose deprivation involves the HIF-1α/PDGF-β signaling Brain Res. (IF 2.9) Pub Date : 2024-03-05 Shi-Na Song, Wen-Ping Dong, Xin-Xin Dong, Fang Guo, Lin Ren, Chang-Xin Li, Jian-Ming Wang
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Formononetin alleviates cerebral ischemia-reperfusion injury in rats by targeting the PARP-1/PARG/Iduna signaling pathway Brain Res. (IF 2.9) Pub Date : 2024-03-05 Jie Luo, Youde Cai, Dingling Wei, Liping Cao, Qiansong He, Yuanhua Wu
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Alterations in the spinal cord, trigeminal nerve ganglion, and infraorbital nerve through inducing compression of the dorsal horn region at the upper cervical cord in trigeminal neuralgia Brain Res. (IF 2.9) Pub Date : 2024-03-04 Ülkü Türk Börü, Zülfükar Kadir Sarıtaş, Fatma Görücü Özbek, Cem Bölük, Hakan Acar, Yusuf Koç, Gökçe Zeytin Demiral
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Study on multi-target effects of the novel HDAC6 inhibitor W5 on Aβ/Cu2+-induced Alzheimer's disease model of rats Brain Res. (IF 2.9) Pub Date : 2024-03-03 Ruihua Liu, Linli Guo, Yanan Zhao, Dan Wu, Jiasi Yu, Ping Liu
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Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model Brain Res. (IF 2.9) Pub Date : 2024-03-02 Daymara Mercerón-Martínez, Laura Alacán Ricardo, Arturo Bejerano Pina, Norma Orama Rojo, Ariel Expósito Seco, Yamilé Vega Hurtado, Bárbara Estupiñán Días, Isabel Fernández, Laura García Pupo, Marquiza Sablón Carrazana, Chryslaine Rodríguez-Tanty, Roberto Menéndez Soto del Valle, William Almaguer-Melian
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Effect of high-frequency repetitive transcranial magnetic stimulation on swallowing function and pneumonia in poststroke dysphagia in rats Brain Res. (IF 2.9) Pub Date : 2024-03-01 Jiemei Chen, Fei Zhao, Jiena Hong, Chao Li, Jiantao Zhang, Yilong Shan, Qiuping Ye, Hongmei Wen
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Inosine pretreatment of pregnant rats ameliorates maternal inflammation-mediated hypomyelination in pups via microglia polarization switch Brain Res. (IF 2.9) Pub Date : 2024-03-01 Yong Han, Jinping Sun, Xiaojuan, Ma·Xin Li, Quanrui Ma
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Propofol-induced hippocampal Neurotoxicity: A mitochondrial perspective Brain Res. (IF 2.9) Pub Date : 2024-02-29 Moein Ebrahimi, Ali Dabbagh, Firoozeh Madadi
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Chronic pain exacerbates memory impairment and pathology of Aβ and tau by upregulating IL-1β and p-65 signaling in a mouse model of Alzheimer’s disease Brain Res. (IF 2.9) Pub Date : 2024-02-29 Wei Wang, Wen-qing Zheng, Xian Du, Shi-cai Chen, Yan-han Chen, qing-yang Ma, Hao Wang, Shan Gao, Rui Tan, Han-ting Zhang, Yan-meng Zhou, Fang-fang Zhang
Chronic pain is linked to cognitive impairment; however, the underlying mechanisms remain unclear. In the present study, we examined these mechanisms in a well-established mouse model of Alzheimer’s disease (AD). Neuropathic pain was modeled in 5-month-old transgenic APPswe/PS1dE9 (APP/PS1) mice by partial ligation of the sciatic nerve on the left side, and chronic inflammatory pain was modeled in