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Effects of microgravity on neural crest stem cells Front. Neurosci. (IF 4.3) Pub Date : 2024-03-27 Yilin Han, Povilas Barasa, Lukas Zeger, Sara B. Salomonsson, Federica Zanotti, Marcel Egli, Barbara Zavan, Martina Trentini, Gunnar Florin, Alf Vaerneus, Håkan Aldskogius, Robert Fredriksson, Elena N. Kozlova
Exposure to microgravity (μg) results in a range of systemic changes in the organism, but may also have beneficial cellular effects. In a previous study we detected increased proliferation capacity and upregulation of genes related to proliferation and survival in boundary cap neural crest stem cells (BC) after MASER14 sounding rocket flight compared to ground-based controls. However, whether these
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COMFORTneo scale in preterm infants during live performed music therapy—Difference between close physical contact and hand touch contact Front. Neurosci. (IF 4.3) Pub Date : 2024-03-27 Susann Kobus, Tim Kleinbeck, Miriam Ader, Monia Vanessa Dewan, Anne-Kathrin Dathe, Nadia Feddahi, Ursula Felderhoff-Mueser, Nora Bruns
There is evidence that music therapy combined with physical contact to parents stabilizes the vital signs of hospitalized preterm infants. Yet, there is no evidence for the difference between simple contact by touching the infant in the incubator or cod, or close physical contact during music therapy sessions (MT). Behavioral effects of the various forms of attention toward the infant during therapy
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An MR-based brain template and atlas for optical projection tomography and light sheet fluorescence microscopy in neuroscience Front. Neurosci. (IF 4.3) Pub Date : 2024-03-27 Stefanie M. A. Willekens, Federico Morini, Tomas Mediavilla, Emma Nilsson, Greger Orädd, Max Hahn, Nunya Chotiwan, Montse Visa, Per-Olof Berggren, Erwin Ilegems, Anna K. Överby, Ulf Ahlgren, Daniel Marcellino
IntroductionOptical Projection Tomography (OPT) and light sheet fluorescence microscopy (LSFM) are high resolution optical imaging techniques, ideally suited for ex vivo 3D whole mouse brain imaging. Although they exhibit high specificity for their targets, the anatomical detail provided by tissue autofluorescence remains limited.MethodsT1-weighted images were acquired from 19 BABB or DBE cleared brains
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Are there effects of light exposure on daytime sleep for rotating shift nurses after night shift?: an EEG power analysis Front. Neurosci. (IF 4.3) Pub Date : 2024-03-27 Soonhyun Yook, Su Jung Choi, Cong Zang, Eun Yeon Joo, Hosung Kim
IntroductionNight-shift workers often face various health issues stemming from circadian rhythm shift and the consequent poor sleep quality. We aimed to study nurses working night shifts, evaluate the electroencephalogram (EEG) pattern of daytime sleep, and explore possible pattern changes due to ambient light exposure (30 lux) compared to dim conditions (<5 lux) during daytime sleep.MoethodsThe study
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Vestibular dysfunction and its association with cognitive impairment and dementia Front. Neurosci. (IF 4.3) Pub Date : 2024-03-27 Cristian Aedo-Sanchez, Patricio Riquelme-Contreras, Fernando Henríquez, Enzo Aguilar-Vidal
The vestibular system plays an important role in maintaining balance and posture. It also contributes to vertical perception, body awareness and spatial navigation. In addition to its sensory function, the vestibular system has direct connections to key areas responsible for higher cognitive functions, such as the prefrontal cortex, insula and hippocampus. Several studies have reported that vestibular
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U-NTCA: nnUNet and nested transformer with channel attention for corneal cell segmentation Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Dan Zhang, Jing Zhang, Saiqing Li, Zhixin Dong, Qinxiang Zheng, Jiong Zhang
BackgroundAutomatic segmentation of corneal stromal cells can assist ophthalmologists to detect abnormal morphology in confocal microscopy images, thereby assessing the virus infection or conical mutation of corneas, and avoiding irreversible pathological damage. However, the corneal stromal cells often suffer from uneven illumination and disordered vascular occlusion, resulting in inaccurate segmentation
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Electrical stimulation of the cuneiform nucleus enhances the effects of rehabilitative training on locomotor recovery after incomplete spinal cord injury Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Myriam I. Scheuber, Carolina Guidolin, Suzi Martins, Andrea M. Sartori, Anna-Sophie Hofer, Martin E. Schwab
Most human spinal cord injuries are anatomically incomplete, leaving some fibers still connecting the brain with the sublesional spinal cord. Spared descending fibers of the brainstem motor control system can be activated by deep brain stimulation (DBS) of the cuneiform nucleus (CnF), a subnucleus of the mesencephalic locomotor region (MLR). The MLR is an evolutionarily highly conserved structure which
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Adaptive fuzzy control for tendon-sheath actuated bending-tip system with unknown friction for robotic flexible endoscope Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Fan Ren, Xiangyu Wang, Ningbo Yu, Jianda Han
IntroductionThe tendon-sheath actuated bending-tip system (TAB) has been widely applied to long-distance transmission scenes due to its high maneuverability, safety, and compliance, such as in exoskeleton robots, rescue robots, and surgical robots design. Due to the suitability of operation in a narrow or tortuous environment, TAB has demonstrated great application potential in the area of minimally
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Deficiency of the paternally-expressed imprinted Peg3 gene in mice has sexually dimorphic consequences for offspring communication and social behaviour Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Hannah R. Tyson, David J. Harrison, Mathew J. Higgs, Anthony R. Isles, Rosalind M. John
IntroductionImprinted genes are expressed from one parental allele as a consequence of epigenetic processes initiated in the germline. Consequently, their ability to influence phenotype depends on their parent-of-origin. Recent research suggests that the sex of the individual expressing the imprinted gene is also important. We have previously reported that genetically wildtype (WT) dams carrying and
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The brain entropy dynamics in resting state Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Xiaoyang Xin, Jiaqian Yu, Xiaoqing Gao
As a novel measure for irregularity and complexity of the spontaneous fluctuations of brain activities, brain entropy (BEN) has attracted much attention in resting-state functional magnetic resonance imaging (rs-fMRI) studies during the last decade. Previous studies have shown its associations with cognitive and mental functions. While most previous research assumes BEN is approximately stationary
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Closing the loop: High-speed robotics with accelerated neuromorphic hardware Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Yannik Stradmann, Johannes Schemmel
The BrainScaleS-2 system is an established analog neuromorphic platform with versatile applications in the diverse fields of computational neuroscience and spike-based machine learning. In this work, we extend the system with a configurable realtime event interface that enables a tight coupling of its distinct analog network core to external sensors and actuators. The 1,000-fold acceleration of the
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Clinical roles of EGFR amplification in diffuse gliomas: a real-world study using the 2021 WHO classification of CNS tumors Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Hai Wang, Xin Zhang, Jiahui Liu, Wenlin Chen, Xiaopeng Guo, Yaning Wang, Yuekun Wang, Hao Xing, Tingyu Liang, Yixin Shi, Delin Liu, Tianrui Yang, Yu Xia, Junlin Li, Jiaming Wu, Qianshu Liu, Tian Qu, Siying Guo, Huanzhang Li, Kun Zhang, Yilin Li, Shanmu Jin, Dachun Zhao, Yu Wang, Wenbin Ma
BackgroundThe 2021 World Health Organization Classification of Central Nervous System Tumors updates glioma subtyping and grading system, and incorporates EGFR amplification (Amp) as one of diagnostic markers for glioblastoma (GBM).PurposeThis study aimed to describe the frequency, clinical value and molecular correlation of EGFR Amp in diffuse gliomas based on the latest classification.MethodsWe reviewed
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The usage and advantages of several common amyotrophic lateral sclerosis animal models Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Lijun Zhou, Meng Xie, Xinxin Wang, Renshi Xu
Amyotrophic lateral sclerosis is a fatal, multigenic, multifactorial neurodegenerative disease characterized by upper and lower motor neuron loss. Animal models are essential for investigating pathogenesis and reflecting clinical manifestations, particularly in developing reasonable prevention and therapeutic methods for human diseases. Over the decades, researchers have established a host of different
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Toluene alters the intrinsic excitability and excitatory synaptic transmission of basolateral amygdala neurons Front. Neurosci. (IF 4.3) Pub Date : 2024-03-26 Kevin Braunscheidel, Michael Okas, John J. Woodward
IntroductionInhalant abuse is an important health issue especially among children and adolescents who often encounter these agents in the home. Research into the neurobiological targets of inhalants has lagged behind that of other drugs such as alcohol and psychostimulants. However, studies from our lab and others have begun to reveal how inhalants such as the organic solvent toluene affect neurons
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Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered Front. Neurosci. (IF 4.3) Pub Date : 2024-03-25 Alex B. Speers, Kirsten M. Wright, Mikah S. Brandes, Nareg Kedjejian, Donald G. Matthews, Maya Caruso, Christopher J. Harris, Seiji Koike, Thuan Nguyen, Joseph F. Quinn, Amala Soumyanath, Nora E. Gray
IntroductionA water extract of Centella asiatica (L.) Urban [Apiaceae] (CAW) has demonstrated cognitive-enhancing effects in mouse models of Alzheimer’s disease and aging, the magnitude of which is influenced by whether CAW is delivered in the drinking water or the diet. These cognitive benefits are accompanied by improvements in oxidative stress and mitochondrial function in the brain, two pathways
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Rapid assessment of peripheral visual crowding Front. Neurosci. (IF 4.3) Pub Date : 2024-03-25 Dilce Tanriverdi, Frans W. Cornelissen
Visual crowding, the phenomenon in which the ability to distinguish objects is hindered in cluttered environments, has critical implications for various ophthalmic and neurological disorders. Traditional methods for assessing crowding involve time-consuming and attention-demanding psychophysical tasks, making routine examination challenging. This study sought to compare trial-based Alternative Forced-Choice
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Modulations in neural pathways excitability post transcutaneous spinal cord stimulation among individuals with spinal cord injury: a systematic review Front. Neurosci. (IF 4.3) Pub Date : 2024-03-25 Shirin Tajali, Gustavo Balbinot, Maureen Pakosh, Dimitry G. Sayenko, Jose Zariffa, Kei Masani
IntroductionTranscutaneous spinal cord stimulation (TSCS), a non-invasive form of spinal cord stimulation, has been shown to improve motor function in individuals living with spinal cord injury (SCI). However, the effects of different types of TSCS currents including direct current (DC-TSCS), alternating current (AC-TSCS), and spinal paired stimulation on the excitability of neural pathways have not
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AA-RGTCN: reciprocal global temporal convolution network with adaptive alignment for video-based person re-identification Front. Neurosci. (IF 4.3) Pub Date : 2024-03-25 Yanjun Zhang, Yanru Lin, Xu Yang
Person re-identification(Re-ID) aims to retrieve pedestrians under different cameras. Compared with image-based Re-ID, video-based Re-ID extracts features from video sequences that contain both spatial features and temporal features. Existing methods usually focus on the most attractive image parts, and this will lead to redundant spatial description and insufficient temporal description. Other methods
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Motion sensitive network for action recognition in control and decision-making of autonomous systems Front. Neurosci. (IF 4.3) Pub Date : 2024-03-25 Jialiang Gu, Yang Yi, Qiang Li
Spatial-temporal modeling is crucial for action recognition in videos within the field of artificial intelligence. However, robustly extracting motion information remains a primary challenge due to temporal deformations of appearances and variations in motion frequencies between different actions. In order to address these issues, we propose an innovative and effective method called the Motion Sensitive
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Multi-consensus formation control by artificial potential field based on velocity threshold Front. Neurosci. (IF 4.3) Pub Date : 2024-03-25 Xiaofei Chang, Jiayue Jiao, Yuenan Li, Bei Hong
This study proposes a multi-consensus formation control algorithm by artificial potential field (APF) method based on velocity threshold. The algorithm improves the multi-consensus technique. This algorithm can split a group of agents into multiple agent groups. Note that the algorithm can easily complete the queue transformation as long as the entire proxy group is connected initially and no specific
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Associations of sleep disorders with all-cause MCI/dementia and different types of dementia – clinical evidence, potential pathomechanisms and treatment options: A narrative review Front. Neurosci. (IF 4.3) Pub Date : 2024-03-24 Geert Mayer, Helmut Frohnhofen, Martha Jokisch, Dirk M. Hermann, Janine Gronewold
Due to worldwide demographic change, the number of older persons in the population is increasing. Aging is accompanied by changes of sleep structure, deposition of beta-amyloid (Aß) and tau proteins and vascular changes and can turn into mild cognitive impairment (MCI) as well as dementia. Sleep disorders are discussed both as a risk factor for and as a consequence of MCI/dementia. Cross-sectional
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Joint-tissue integrative analysis identifies high-risk genes for Parkinson’s disease Front. Neurosci. (IF 4.3) Pub Date : 2024-03-23 Ya-Shi Wu, Wen-Han Zheng, Tai-Hang Liu, Yan Sun, Yu-Ting Xu, Li-Zhen Shao, Qin-Yu Cai, Ya Qin Tang
The loss of dopaminergic neurons in the substantia nigra and the abnormal accumulation of synuclein proteins and neurotransmitters in Lewy bodies constitute the primary symptoms of Parkinson’s disease (PD). Besides environmental factors, scholars are in the early stages of comprehending the genetic factors involved in the pathogenic mechanism of PD. Although genome-wide association studies (GWAS) have
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Reduced contrast sensitivity function is correlated with changes to cone photoreceptors in simple high myopia Front. Neurosci. (IF 4.3) Pub Date : 2024-03-22 Jiefang Wang, Xinting Liu, Jing Huang, Ruoyun Deng, Sijun Zhao, Yulei Chen, Zhaohe Chen, Yanli Wang, Yu Rong, Qian Liu, Jia Qu, Xinjie Mao
PurposeTo investigate the contrast sensitivity function (CSF) changes in simple high myopia (SHM) and evaluate the correlations between these changes with the early changes in the retinal microstructure.MethodsThis prospective study comprised 81 subjects, 20 with emmetropia (EM), 26 with low myopia and moderate myopia (LM/MM), and 35 with SHM. The area under the log CSF curve (AULCSF) and the cut-off
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Research status and trends of physical activity on depression or anxiety: a bibliometric analysis Front. Neurosci. (IF 4.3) Pub Date : 2024-03-22 Xin-Yue Zhang, Fang Ye, Zi-Han Yin, Ya-Qin Li, Qiong-Nan Bao, Man-Ze Xia, Zheng-Hong Chen, Wan-Qi Zhong, Ke-Xin Wu, Jin Yao, Fan-Rong Liang
BackgroundAnxiety and depression are prevalent mental disorders. As modern society continues to face mounting pressures, the incidence of anxiety and depression is on the rise. In recent years, there has been an increasing breadth of research exploring the relationship between anxiety, depression, and physical activity (PA). However, the current research progress and future development trends are unclear
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Comparative development of the serotonin- and FMRFamide-immunoreactive components of the nervous system in two distantly related ribbon worm species (Nemertea, Spiralia) Front. Neurosci. (IF 4.3) Pub Date : 2024-03-22 Jörn von Döhren
IntroductionNeurodevelopment in larval stages of non-model organisms, with a focus on the serotonin- and FMRFamide-immunoreactive components, has been in the focus of research in the recent past. However, some taxonomic groups remain understudied. Nemertea (ribbon worms) represent such an understudied clade with only few reports on nervous system development mostly from phylogenetically or developmentally
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Large-scale real-world data on a multidisciplinary approach to spinal cord stimulation for persistent spinal pain syndromes: first evaluation of the Neuro-Pain® nationwide screening and follow-up interactive register Front. Neurosci. (IF 4.3) Pub Date : 2024-03-22 Lisa Bernaerts, Ella Roelant, Frederic Lecomte, Maarten Moens, Jean-Pierre Van Buyten, Bart Billet, Bart Bryon, Martine Puylaert, Tuna Turgay, Maureen Malone, Tom Theys, Jan Van Zundert, Anne Berquin, Erwin Crombez, Olivier De Coster, Johan Vangeneugden, Huynh Giao Ly, Marleen Louagie, Guy Henri Hans
IntroductionSpinal cord stimulation is a common treatment option for neuropathic pain conditions. Despite its extensive use and multiple technological evolutions, long term efficacy of spinal cord stimulation is debated. Most studies on spinal cord stimulation include a rather limited number of patients and/or follow-ups over a limited period. Therefore, there is an urgent need for real-world, long-term
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The impact of estradiol on serotonin, glutamate, and dopamine systems Front. Neurosci. (IF 4.3) Pub Date : 2024-03-22 Peyton Christine Bendis, Sydney Zimmerman, Anna Onisiforou, Panos Zanos, Polymnia Georgiou
Estradiol, the most potent and prevalent member of the estrogen class of steroid hormones and is expressed in both sexes. Functioning as a neuroactive steroid, it plays a crucial role in modulating neurotransmitter systems affecting neuronal circuits and brain functions including learning and memory, reward and sexual behaviors. These neurotransmitter systems encompass the serotonergic, dopaminergic
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Research hotspots and trends on acupuncture treatment for headache: a bibliometric analysis from 2003 to 2023 Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Shun Zhao, Songfeng Hu, Yujing Luo, Wangjun Li, Fenfen Zhao, Changkang Wang, Fanlei Meng, Xingwei He
BackgroundWhile acupuncture treatment has gained extensive usage in addressing headaches, there remains a notable gap in the literature analysis for this field. Therefore, this study aims to conduct a literature review using Citespace, VOSviewer, and Bibliometrix, aiming to examine the current status, strengths, and potential future directions in the utilization of acupuncture for headache treatment
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A brain functional network feature extraction method based on directed transfer function and graph theory for MI-BCI decoding tasks Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Pengfei Ma, Chaoyi Dong, Ruijing Lin, Huanzi Liu, Dongyang Lei, Xiaoyan Chen, Huan Liu
BackgroundThe development of Brain-Computer Interface (BCI) technology has brought tremendous potential to various fields. In recent years, prominent research has focused on enhancing the accuracy of BCI decoding algorithms by effectively utilizing meaningful features extracted from electroencephalographic (EEG) signals.ObjectiveThis paper proposes a method for extracting brain functional network features
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The white matter characteristic of the genu of corpus callosum coupled with pain intensity and negative emotion scores in patients with trigeminal neuralgia: a multivariate analysis Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Baijintao Sun, Chuan Zhang, Kai Huang, Anup Bhetuwal, Xuezhao Yang, Chuan Jing, Hongjian Li, Hongyu Lu, Qingwei Zhang, Hanfeng Yang
BackgroundTrigeminal neuralgia (TN) is a chronic neuropathic pain disorder that not only causes intense pain but also affects the psychological health of patients. Since TN pain intensity and negative emotion may be grounded in our own pain experiences, they exhibit huge inter-individual differences. This study investigates the effect of inter-individual differences in pain intensity and negative emotion
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Development of an artificial intelligence based occupational noise induced hearing loss early warning system for mine workers Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Milka C. I. Madahana, John E. D. Ekoru, Ben Sebothoma, Katijah Khoza-Shangase
IntroductionOccupational Noise Induced Hearing Loss (ONIHL) is one of the most prevalent conditions among mine workers globally. This reality is due to mine workers being exposed to noise produced by heavy machinery, rock drilling, blasting, and so on. This condition can be compounded by the fact that mine workers often work in confined workspaces for extended periods of time, where little to no attenuation
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The role of neurovascular coupling dysfunction in cognitive decline of diabetes patients Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Lin Feng, Ling Gao
Neurovascular coupling (NVC) is an important mechanism to ensure adequate blood supply to active neurons in the brain. NVC damage can lead to chronic impairment of neuronal function. Diabetes is characterized by high blood sugar and is considered an important risk factor for cognitive impairment. In this review, we provide fMRI evidence of NVC damage in diabetic patients with cognitive decline. Combined
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Brain serotonin and serotonin transporter expression in male and female postnatal rat offspring in response to perturbed early life dietary exposures Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Xin Ye, Shubhamoy Ghosh, Bo-Chul Shin, Amit Ganguly, Liesbeth Maggiotto, Jonathan P. Jacobs, Sherin U. Devaskar
IntroductionSerotonin (5-HT) is critical for neurodevelopment and the serotonin transporter (SERT) modulates serotonin levels. Perturbed prenatal and postnatal dietary exposures affect the developing offspring predisposing to neurobehavioral disorders in the adult. We hypothesized that the postnatal brain 5-HT-SERT imbalance associated with gut dysbiosis forms the contributing gut-brain axis dependent
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Neural correlates of breath work, mental imagery of yoga postures, and meditation in yoga practitioners: a functional near-infrared spectroscopy study Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Xiawen Li, Yu Zhou, Chenping Zhang, Hongbiao Wang, Xiaochun Wang
ObjectivePrevious research has shown numerous health benefits of yoga, a multicomponent physical and mental activity. The three important aspects of both traditional and modern yoga are breath work, postures, and meditation. However, the neural mechanisms associated with these three aspects of yoga remain largely unknown. The present study investigated the neural underpinnings associated with each
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Secondary language impairment in posterior cortical atrophy: insights from sentence repetition Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Samrah Ahmed, Josie Caswell, Christopher R. Butler, Arpita Bose
IntroductionPosterior cortical atrophy (PCA) is a neurodegenerative syndrome characterized by progressive impairment in visuospatial and perceptual function linked to atrophy of the occipito-parietal cortex. Besides the salient visual impairment, several studies have documented subtle changes in language may also be present. Sentence repetition is a highly constrained linguistic task involving multiple
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Bipolar disorder and the gut microbiota: a bibliometric analysis Front. Neurosci. (IF 4.3) Pub Date : 2024-03-21 Xiaoxiao Lin, Jinyu Huang, Shuai Wang, Kai Zhang
BackgroundPrevious studies have explored the relationship between bipolar disorder and gut microbiota. However, there has been no bibliometric analysis to summarize and analyze these publications. Our objective was to perform a bibliometric analysis to investigate the current status and frontiers of the publications in the field of the association between bipolar disorder and the gut microbiota.MethodsWe
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Predicting interindividual response to theta burst stimulation in the lower limb motor cortex using machine learning Front. Neurosci. (IF 4.3) Pub Date : 2024-03-20 Natsuki Katagiri, Tatsunori Saho, Shuhei Shibukawa, Shigeo Tanabe, Tomofumi Yamaguchi
Using theta burst stimulation (TBS) to induce neural plasticity has played an important role in improving the treatment of neurological disorders. However, the variability of TBS-induced synaptic plasticity in the primary motor cortex prevents its clinical application. Thus, factors associated with this variability should be explored to enable the creation of a predictive model. Statistical approaches
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β-amyloid accumulation enhances microtubule associated protein tau pathology in an APPNL-G-F/MAPTP301S mouse model of Alzheimer’s disease Front. Neurosci. (IF 4.3) Pub Date : 2024-03-20 Lulu Jiang, Rebecca Roberts, Melissa Wong, Lushuang Zhang, Chelsea Joy Webber, Jenna Libera, Zihan Wang, Alper Kilci, Matthew Jenkins, Alejandro Rondón Ortiz, Luke Dorrian, Jingjing Sun, Guangxin Sun, Sherif Rashad, Caroline Kornbrek, Sarah Anne Daley, Peter C. Dedon, Brian Nguyen, Weiming Xia, Takashi Saito, Takaomi C. Saido, Benjamin Wolozin
IntroductionThe study of the pathophysiology study of Alzheimer’s disease (AD) has been hampered by lack animal models that recapitulate the major AD pathologies, including extracellular -amyloid (A) deposition, intracellular aggregation of microtubule associated protein tau (MAPT), inflammation and neurodegeneration.MethodsThe humanized APPNL-G-F knock-in mouse line was crossed to the PS19 MAPTP301S
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A rotary transformer cross-subject model for continuous estimation of finger joints kinematics and a transfer learning approach for new subjects Front. Neurosci. (IF 4.3) Pub Date : 2024-03-20 Chuang Lin, Zheng He
IntroductionSurface Electromyographic (sEMG) signals are widely utilized for estimating finger kinematics continuously in human-machine interfaces (HMI), and deep learning approaches are crucial in constructing the models. At present, most models are extracted on specific subjects and do not have cross-subject generalizability. Considering the erratic nature of sEMG signals, a model trained on a specific
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Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study Front. Neurosci. (IF 4.3) Pub Date : 2024-03-20 Jessie Mosso, Guillaume Briand, Katarzyna Pierzchala, Dunja Simicic, Alejandra Sierra, Ali Abdollahzadeh, Ileana O. Jelescu, Cristina Cudalbu
IntroductionType C hepatic encephalopathy (HE) is a decompensating event of chronic liver disease leading to severe motor and cognitive impairment. The progression of type C HE is associated with changes in brain metabolite concentrations measured by 1H magnetic resonance spectroscopy (MRS), most noticeably a strong increase in glutamine to detoxify brain ammonia. In addition, alterations of brain
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A systematic review of automated methods to perform white matter tract segmentation Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Ankita Joshi, Hailong Li, Nehal A. Parikh, Lili He
White matter tract segmentation is a pivotal research area that leverages diffusion-weighted magnetic resonance imaging (dMRI) for the identification and mapping of individual white matter tracts and their trajectories. This study aims to provide a comprehensive systematic literature review on automated methods for white matter tract segmentation in brain dMRI scans. Articles on PubMed, ScienceDirect
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Self-esteem mediates the relationship between the parahippocampal gyrus and decisional procrastination at resting state Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Weili Ling, Fan Yang, Taicheng Huang, Xueting Li
When faced with a conflict or dilemma, we tend to postpone or even avoid making a decision. This phenomenon is known as decisional procrastination. Here, we investigated the neural correlates of this phenomenon, in particular the parahippocampal gyrus (PHG) that has previously been identified in procrastination studies. In this study, we applied an individual difference approach to evaluate participants’
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Integrated use of biofeedback and neurofeedback techniques in treating pathological conditions and improving performance: a narrative review Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Beatrice Tosti, Stefano Corrado, Stefania Mancone, Tommaso Di Libero, Angelo Rodio, Alexandro Andrade, Pierluigi Diotaiuti
In recent years, the scientific community has begun tо explore the efficacy оf an integrated neurofeedback + biofeedback approach іn various conditions, both pathological and non-pathological. Although several studies have contributed valuable insights into its potential benefits, this review aims tо further investigate its effectiveness by synthesizing current findings and identifying areas for future
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Screening effects of HCN channel blockers on sleep/wake behavior in zebrafish Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Fusun Doldur-Balli, Sandra P. Smieszek, Brendan T. Keenan, Amber J. Zimmerman, Olivia J. Veatch, Christos M. Polymeropoulos, Gunther Birznieks, Mihael H. Polymeropoulos
Hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels generate electrical rhythmicity in various tissues although primarily heart, retina and brain. The HCN channel blocker compound, Ivabradine (Corlanor), is approved by the US Food and Drug Administration (FDA) as a medication to lower heart rate by blocking hyperpolarization activated inward current in the sinoatrial node. In addition
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GABAergic synapses from the ventral lateral septum to the paraventricular nucleus of hypothalamus modulate anxiety Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Ying-Juan Liu, Yan Wang, Jiao-Wen Wu, Jie Zhou, Bai-Lin Song, Yi Jiang, Lai-Fu Li
Emotional disorders, such as anxiety and depression, represent a major societal problem; however, the underlying neurological mechanism remains unknown. The ventral lateral septum (LSv) is implicated in regulating processes related to mood and motivation. In this study, we found that LSv GABAergic neurons were significantly activated in mice experiencing chronic social defeat stress (CSDS) after exposure
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Efficacy of repetitive transcranial magnetic stimulation with different application parameters for post-stroke cognitive impairment: a systematic review Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Yuhan Wang, Linjia Wang, Xixiu Ni, Minjiao Jiang, Ling Zhao
BackgroundCognitive impairment is a prevalent consequence of stroke, seriously affecting recovery and quality of life while imposing substantial burdens on both patients’ families and society. Repetitive transcranial magnetic stimulation (rTMS) has emerged as an effective intervention for post-stroke cognitive impairment (PSCI). However, the a lack of standardized and explicit guidelines regarding
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Transcranial electrical stimulation during functional magnetic resonance imaging in patients with genetic generalized epilepsy: a pilot and feasibility study Front. Neurosci. (IF 4.3) Pub Date : 2024-03-19 Zachary Cohen, Mirja Steinbrenner, Rory J. Piper, Chayanin Tangwiriyasakul, Mark P. Richardson, David J. Sharp, Ines R. Violante, David W. Carmichael
ObjectiveA third of patients with epilepsy continue to have seizures despite receiving adequate antiseizure medication. Transcranial direct current stimulation (tDCS) might be a viable adjunct treatment option, having been shown to reduce epileptic seizures in patients with focal epilepsy. Evidence for the use of tDCS in genetic generalized epilepsy (GGE) is scarce. We aimed to establish the feasibility
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Frontiers | Attentional state-synchronous peripheral electrical stimulation during action observation induced distinct modulation of corticospinal plasticity after stroke Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Chang Hyeon Jeong, Hyunmi Lim, Jiye Lee, Hye Sun Lee, Jeonghun Ku, Youn Joo Kang
Introduction Brain computer interface-based action observation (BCI-AO) is a promising technique in detecting the user's cortical state of visual attention and providing feedback to assist rehabilitation. Peripheral nerve electrical stimulation (PES) is a conventional method used to enhance outcomes in upper extremity function by increasing activation in the motor cortex. In this study, we examined
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Effects of hyperbaric oxygen therapy on autistic behaviors and GRIN2B gene expression in valproic acid-exposed rats Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Yalda Mohtaj Khorassani, Ali Moghimi, Mohammad Reza Khakzad, Masoud Fereidoni, Delaram Hassani, Javad Torbati Gah
IntroductionAutism is a complex neurodevelopmental condition characterized by deficits in social interaction, communication, and restricted repetitive behaviors. Hyperbaric oxygen therapy (HBOT) has emerged as a potential treatment for autism, although its effects on behavior and gene expression are not well understood. The GRIN2B gene, known for its involvement in encoding a glutamate receptor subunit
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Molecular pathways in experimental glaucoma models Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Klaudia Bugara, Anna Pacwa, Adrian Smedowski
Glaucoma is a complex and progressive disease that primarily affects the optic nerve axons, leading to irreversible vision loss. Although the exact molecular mechanisms underlying glaucoma pathogenesis are not fully understood, it is believed that except increased intraocular pressure, a combination of genetic and environmental factors play a role in the development of the disease. Animal models have
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Proportional sway-based electrotactile feedback improves lateral standing balance Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 V. S. Raghav Hari Krishna, Jeonghee Kim, Shuo-Hsiu Chang, Yoonsuck Choe, Hangue Park
IntroductionPlantar cutaneous augmentation is a promising approach in balance rehabilitation by enhancing motion-dependent sensory feedback. The effect of plantar cutaneous augmentation on balance has been mainly investigated in its passive form (e.g., textured insole) or on lower-limb amputees. In this study, we tested the effect of plantar cutaneous augmentation on balance in its active form (i.e
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Opsin expression varies across larval development and taxa in pteriomorphian bivalves Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Md Shazid Hasan, Kyle E. McElroy, Jorge A. Audino, Jeanne M. Serb
IntroductionMany marine organisms have a biphasic life cycle that transitions between a swimming larva with a more sedentary adult form. At the end of the first phase, larvae must identify suitable sites to settle and undergo a dramatic morphological change. Environmental factors, including photic and chemical cues, appear to influence settlement, but the sensory receptors involved are largely unknown
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Integrating multi-omics data to reveal the effect of genetic variant rs6430538 on Alzheimer's disease risk Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Shizheng Qiu, Meili Sun, Yanwei Xu, Yang Hu
IntroductionGrowing evidence highlights a potential genetic overlap between Alzheimer's disease (AD) and Parkinson's disease (PD); however, the role of the PD risk variant rs6430538 in AD remains unclear.MethodsIn Stage 1, we investigated the risk associated with the rs6430538 C allele in seven large-scale AD genome-wide association study (GWAS) cohorts. In Stage 2, we performed expression quantitative
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Sound-localization-related activation and functional connectivity of dorsal auditory pathway in relation to demographic, cognitive, and behavioral characteristics in age-related hearing loss Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Junzhi Wu, Shuai Nie, Chunlin Li, Xing Wang, Ye Peng, Jiaqi Shang, Linan Diao, Hongping Ding, Qian Si, Songjian Wang, Renjie Tong, Yutang Li, Liwei Sun, Juan Zhang
BackgroundPatients with age-related hearing loss (ARHL) often struggle with tracking and locating sound sources, but the neural signature associated with these impairments remains unclear.Materials and methodsUsing a passive listening task with stimuli from five different horizontal directions in functional magnetic resonance imaging, we defined functional regions of interest (ROIs) of the auditory
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Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer’s disease Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Jeffrey S. Phillips, Nagesh Adluru, Moo K. Chung, Hamsanandini Radhakrishnan, Christopher A. Olm, Philip A. Cook, James C. Gee, Katheryn A. Q. Cousins, Sanaz Arezoumandan, David A. Wolk, Corey T. McMillan, Murray Grossman, David J. Irwin
IntroductionMultimodal evidence indicates Alzheimer’s disease (AD) is characterized by early white matter (WM) changes that precede overt cognitive impairment. WM changes have overwhelmingly been investigated in typical, amnestic mild cognitive impairment and AD; fewer studies have addressed WM change in atypical, non-amnestic syndromes. We hypothesized each non-amnestic AD syndrome would exhibit WM
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Postembryonic development and male paedomorphosis in Osedax (Siboglinidae, Annelida) Front. Neurosci. (IF 4.3) Pub Date : 2024-03-18 Katrine Worsaae, Alice Rouan, Elaine Seaver, Norio Miyamoto, Ekin Tilic
Most species of the bone-devouring marine annelid, Osedax, display distinct sexual dimorphism with macroscopic sedentary females rooted in bones and free-living microscopic dwarf males. The paedomorphic male resembles the non-feeding metatrochophore larva in size, presence of eight pairs of chaetae, and a head ciliation potentially representing a residual prototroch. The male development may thus uniquely
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Effect of “needle sensation” and the real-time changes in autonomic nervous system activity during acupuncture analgesia Front. Neurosci. (IF 4.3) Pub Date : 2024-03-15 Zehua Liu, Jinglei Huang, Dingshang Yan, Sha Liang, Shatong Zhao, Mengzhen Zhang, Zhongwen Li, Chuliang Jiang, Xiang Yin, Yingjun Zhang, Tianshu Hou, Min Feng
IntroductionAcupuncture analgesia (AA) is widely used in clinical practice. The autonomic nervous system (ANS) may be an important pathway for acupuncture signal transduction. However, real-time changes in autonomic function during AA and the effect of “needle sensation” remain unclear.MethodsWe established a human pain model in healthy adults and randomly assigned 128 participants to the model, sham
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Improving wheelchair user sitting posture to alleviate lumbar fatigue: a study utilizing sEMG and pressure sensors Front. Neurosci. (IF 4.3) Pub Date : 2024-03-15 Zizheng Huang, Jianwei Cui, Yuanbo Wang, Siji Yu
BackgroundThe wheelchair is a widely used rehabilitation device, which is indispensable for people with limited mobility. In the process of using a wheelchair, they often face the situation of sitting for a long time, which is easy to cause fatigue of the waist muscles of the user. Therefore, this paper hopes to provide more scientific guidance and suggestions for the daily use of wheelchairs by studying
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Contralateral acupuncture for migraine without aura: a randomized trial protocol with multimodal MRI Front. Neurosci. (IF 4.3) Pub Date : 2024-03-15 Ziwen Chen, Qifu Li, Yi Lu, Gaoyangzi Huang, Ya Huang, Xianmei Pei, Yi Gong, Bingkui Zhang, Xin Tang, Zili Liu, Taipin Guo, Fanrong Liang
IntroductionMigraine is a common clinical disorder, ranks as the second most disabling disease worldwide, and often manifests with unilateral onset. Contralateral acupuncture (CAT), as a classical acupuncture method, has been proven to be effective in the treatment of migraine without aura (MWoA). However, its neural mechanisms have not been investigated using multimodal magnetic resonance imaging
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Theta-frequency medial septal nucleus deep brain stimulation increases neurovascular activity in MK-801-treated mice Front. Neurosci. (IF 4.3) Pub Date : 2024-03-15 Lindsey M. Crown, Kofi A. Agyeman, Wooseong Choi, Nancy Zepeda, Ege Iseri, Pooyan Pahlavan, Steven J. Siegel, Charles Liu, Vasileios Christopoulos, Darrin J. Lee
IntroductionDeep brain stimulation (DBS) has shown remarkable success treating neurological and psychiatric disorders including Parkinson’s disease, essential tremor, dystonia, epilepsy, and obsessive-compulsive disorder. DBS is now being explored to improve cognitive and functional outcomes in other psychiatric conditions, such as those characterized by reduced N-methyl-D-aspartate (NMDA) function