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Relationship of Day-by-Day Blood Pressure Variability and Admission Stroke Severity in Acute Ischemic Stroke. Neurologist (IF 1.2) Pub Date : 2024-03-06 Yuan Zhu, Minghua Wu, Yawei Zheng, Xintong Wang, Jingyi Xiayang, Tianrui Zhang, Shana Wang, Zhuyuan Fang
Research on the association between stroke severity and day-by-day blood pressure variability (BPV) in acute ischemic stroke (AIS) is rare as the majority focus on the blood pressure (BP) or the short-term BPV. Our study aims to explore the exact roles of daily BPV through the 7-day commencement on stroke severity in AIS.
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Association of Systemic Immune-Inflammation Index With Stroke and Mortality Rates: Evidence From the NHANES Database. Neurologist (IF 1.2) Pub Date : 2024-02-27 Lei Yang, Maode Wang
This study aimed to examine the association of the systemic immune-inflammation index (SII) with stroke and mortality rates using data from the National Health and Nutrition Examination Survey (NHANES).
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Neurological Diagnosis: Artificial Intelligence Compared With Diagnostic Generator. Neurologist (IF 1.2) Pub Date : 2024-02-20 Pasquale F Finelli
Artificial intelligence has recently become available for widespread use in medicine, including the interpretation of digitized information, big data for tracking disease trends and patterns, and clinical diagnosis. Comparative studies and expert opinion support the validity of imaging and data analysis, yet similar validation is lacking in clinical diagnosis. Artificial intelligence programs are here
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Intracranial Hypertension Associated With Poly-Cranio-Radicular-Neuropathies: A Case Report and Review of the Literature. Neurologist (IF 1.2) Pub Date : 2024-02-19 James E Eaton, Ipek Oguz, Habeeb Kazimuddin, Francesca Bagnato
We present the case of a gentleman who developed rapidly progressive vision loss, ophthalmo-paresis, and flaccid quadriparesis in the context of severe intracranial hypertension. We reviewed the available cases in the literature to increase awareness of this rare clinical entity.Case Report:A 36-year-old man developed rapidly progressive vision loss, ophthalmo-paresis, and flaccid quadriparesis. He
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Correlations of 2 Novel Inflammation Indexes With the Risk for Early Neurological Deterioration in Acute Ischemic Stroke Patients After Intravenous Thrombolytic Therapy. Neurologist (IF 1.2) Pub Date : 2024-02-07 Nuo Wang, Ling Wang, Minmin Zhang, Benqiang Deng, Tao Wu
Elevation of the systemic immune inflammation (SII) index and system inflammation response index (SIRI) is known to be associated with higher risk of stroke and all-cause death. However, no study has reported their correlation with early neurological deterioration (END) following recombinant tissue-type plasminogen activator (IV-rtPA) in acute ischemic stroke patients. The aim of this study was to
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Cerebral Tumefactive Inflammatory Lesion Occurrence During Ixekizumab Treatment in a Patient With Active Psoriatic Arthritis. Neurologist (IF 1.2) Pub Date : 2024-01-22 Antonio Marangi, Francesco Benvenuti, Linda Mazzai, Giulio Riva, Diana Polo, Ilaria Franceschetti, Pierino De Sandre, Mariano Agostino Zanusso, Giovanni Scanelli, Francesco Perini
Ixekizumab is an anti-interleukin-17A (IL-17A) humanized monoclonal antibody approved for the treatment of moderate-to-severe plaque psoriasis, active psoriatic arthritis, and ankylosing spondylitis. Central nervous system inflammatory manifestations are atypical during therapy with IL-17A inhibitors, with only one case of myelitis described to date.
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Identification of Senescence-Related Biomarkers and Regulatory Networks in Intracerebral Hemorrhage. Neurologist (IF 1.2) Pub Date : 2024-01-22 Yan Wang, Ling Chen
Intracerebral hemorrhage (ICH) is a severe neurological disorder with substantial societal implications. Cellular senescence plays a critical role in ICH pathogenesis. This study aims to identify senescence-related biomarkers in ICH for diagnostic and therapeutic purposes.
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Characteristics of Cerebral Venous Sinus Thrombosis Due to Autoimmune Diseases: A Single-Center Retrospective Observational Study. Neurologist (IF 1.2) Pub Date : 2024-01-22 Furkan Saridas, Gizem Mesut, Yasemin Dinc, Emine Rabia Koc, Rifat Ozpar, Bahattin Hakyemez, Omer Faruk Turan
Cerebral venous sinus thrombosis (CVST) is a cerebrovascular disease characterized by thrombosis of the cerebral venous or dural sinuses. Autoimmune diseases (AD) are important causes of CVST. This study aims to reveal the differences between CVST associated with autoimmune diseases compared with other causes (OCs) and Behcet's syndrome (BS) compared with other ADs.
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Association Between Insulin Resistance Markers and Poor Prognosis in Patients With Acute Ischemic Stroke After Intravenous Thrombolysis. Neurologist (IF 1.2) Pub Date : 2024-01-22 Haimei Liu, Denglu Liu, Peng Zuo
This study aims to investigate the significance of insulin resistance markers in predicting poor prognosis in acute ischemic stroke (AIS) patients after intravenous thrombolysis and to establish the corresponding nomogram.
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Analysis of Clinical Characteristics and Influencing Factors of Early Neurological Deterioration in Patients With Mild Stroke by Intravenous Alteplase Therapy. Neurologist (IF 1.2) Pub Date : 2024-01-22 Xin-Lei Mao, Si-Si He, Cai-Dan Lin, Xiang-Dong Huang, Jun Sun
Thrombolysis treatment for patients with mild stroke is controversial. The aim of our study was to investigate the clinical characteristics and influencing factors of early neurological deterioration (END) in this group of patients.
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Anticonvulsant Agents for Treatment of Restless Legs Syndrome: A Case Report With Lamotrigine and a Review of the Literature. Neurologist (IF 1.2) Pub Date : 2024-01-22 Jawad Al-Kassmy, Mohammed Alsalmi, Woojin Kang, Philippe Huot
Restless Legs Syndrome (RLS) is a neurological disorder primarily treated with pregabalin and gabapentin, followed by dopamine agonists later in the process due to the risk of augmenting RLS symptoms. In addition, clinical reports have disclosed varying degrees of success employing other agents in patients unresponsive to traditional agents. Here, we present a patient who had success in the reduction
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Correlation Between Risk Factors, Degree of Vascular Restenosis, and Inflammatory Factors After Interventional Treatment for Stroke: A Two-center Retrospective Study. Neurologist (IF 1.2) Pub Date : 2024-01-22 Liang Hao, Mingming Gao, Wei Guo, Zhigang Yao
To study the correlation between risk factors, degree of vascular restenosis, and inflammatory factors after interventional treatment for stroke.
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Barthel Index, SPAN-100, and NIHSS Studies on the Predictive Value of Prognosis in Patients With Thrombolysis. Neurologist (IF 1.2) Pub Date : 2024-01-22 Meng Fu, Yani Fan, Shuangmei Yan, Sujie Wang, Sai Zhang, Feifei Chen, Rui Han, Xiaohong He, Ping Gu, Jian Li, Lili Chen
We mainly explore the predictive value of Barthel Index (BI), SPAN-100, and National Institute of Health stroke scale (NIHSS) scores on clinical prognosis and functional outcomes in thrombolytic patients and compare the differences in the predictive values of the above 3 scales so as to provide an effective basis to evaluate the prognosis of thrombolytic patients.
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A Mild Phenotype of Overlapping Syndrome With Myelin-Oligodendrocyte Glycoprotein and Glial Fibrillary Acidic Protein Immunoglobulin G: Mimicking Viral Meningitis in a Patient. Neurologist (IF 1.2) Pub Date : 2023-12-21 Danmei Pan, Jina Gu, Chengjun Zeng, Lin Chen
Glial fibrillary acidic protein (GFAP) astrocytopathy, an autoimmune central nervous system disorder characterized by the development of immunoglobulin G reactive with GFAP, has received growing attention in recent years. It is documented that GFAP-immunoglobulin G and other autoantibodies can be both detected in some patients. However, the coexistence of anti-myelin-oligodendrocyte glycoprotein (MOG)
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Feasibility and Clinical Outcome Predictors of Mechanical Thrombectomy in Distal Arterial Occlusion Causing Acute Ischemic Stroke: A Monocentric Retrospective Study. Neurologist (IF 1.2) Pub Date : 2023-11-07 Beihai Ge, Limei Pan, Huihua Liu
The feasibility and clinical outcome predictors of mechanical thrombectomy (MT) for strokes caused by distal arterial occlusion (DAO) remain the subject of debate.
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HaNDL Syndrome: The Innocent Lymphocytic Pleocytosis. Neurologist (IF 1.2) Pub Date : 2023-11-06 Kadriye Güleda Keskin, Irem Carus, Isil Kalyoncu Aslan, Eren Gözke
HaNDL syndrome is a transient and rare condition that presents with neurological deficit and headache accompanied by lymphocytosis on cerebrospinal fluid (CSF) analysis. It is usually characterized by spontaneous recovery without neurological sequelae. This is a benign condition, which has not yet been adequately defined and includes many diseases in the differential diagnosis. We indicated 2 different
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Coronavirus Disease 2019 Infection in Cervical Artery Dissections. Neurologist (IF 1.2) Pub Date : 2023-11-06 Waseem Wahood, Kelly D Flemming, Giuseppe Lanzino, Zafer Keser
Most cervical artery dissection (CeAD) cases are spontaneous or due to minor traumas, and preceding viral infections have been suggested to be a triggering event for CeAD in some. Herein, we analyze the prevalence of coronavirus disease 2019 (COVID-19) in hospitalized patients with CeAD using a national database.
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Mechanical Thrombectomy in Anticoagulated Patients With Acute Ischemic Stroke: A Meta-Analysis. Neurologist (IF 1.2) Pub Date : 2023-11-06 HaoLiang Zhang, Shiqin Chen, QianYuan Zhu, ZongShan Li, Tian Lv, Chengjiang Liu
According to a previous studies, mechanical thrombectomy(MT) is safe for anticoagulated patients. However, the safety and prognosis of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKA) have not been compared with those of MT.This meta-analysis aimed at determining the efficacy of DOACs or VKA for patients after MT.
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Short-term Exposure to Air Pollution and the Incidence and Mortality of Stroke: A Meta-Analysis. Neurologist (IF 1.2) Pub Date : 2023-11-03 Wenjian Lin, Jie Pan, Jiahe Li, Xiaoyu Zhou, Xueyuan Liu
The relationship between short-term exposure to various air pollutants [particulate matter <10 μm (PM10), particulate matter <2.5 μm (PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide, and ozone (O3)] and the incidence and mortality of stroke remain unclear.
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Does Initiation of Prophylactic Antiseizure Medication Improve Neurological Outcomes in Patients With Acute Intracerebral Hemorrhage?: A Critically Appraised Topic. Neurologist (IF 1.2) Pub Date : 2023-11-01 Nikita Chhabra, Amy Z Crepeau, Bart M Demaerschalk, Molly G Knox, William David Freeman, Cristina Valencia Sanchez, Lisa A Marks, Cumara B O'Carroll
The objective of this study was to critically assess current evidence regarding the role of prophylactic antiseizure medication in patients presenting with acute intracerebral hemorrhage (ICH).
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The Clinical Characteristics of Heart Rate Variability After Stroke: A Systematic Review. Neurologist (IF 1.2) Pub Date : 2023-10-26 Xue Bai, Na Wang, Yueqiao Si, Yunchang Liu, Ping Yin, Chunmei Xu
The autonomic nervous system dysfunction has been reported in up to 76% of stroke patients 7 days after an acute stroke. Heart rate variability (HRV) is one of the important indicators reflecting the balance of sympathetic and parasympathetic nerves. Therefore, we performed a systematic literature review of existing literature on the association between heart rate variability and the different types
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Utility of the Systemic Inflammation Response Index as a Predictor of Pneumonia After Spontaneous Intracerebral Hemorrhage. Neurologist (IF 1.2) Pub Date : 2023-10-23 Tingting Yu, Zhengyang Wang
We sought to determine whether the initial Systemic Inflammatory Response Index (SIRI) was associated with pneumonia after spontaneous intracerebral hemorrhage (SICH) in hospitalized patients.
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Modified Magnetic Resonance Imaging Burden of Cerebral Small Vessel Disease and Related Risk Factors in Patients With Thalassemia. Neurologist (IF 1.2) Pub Date : 2023-10-20 Xiuying Liu, Kunling Yang, Lanfeng Sun, Qi Huang, Lianqing Long, Sijie Ou, Xing Wei, Yuan Wu
This study aimed to explore the burden of magnetic resonance imaging (MRI) of cerebral small vessel disease (CSVD) in patients with thalassemia and related risk factors.
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BRAT1-Associated Leukodystrophy Exacerbated by Classic Hodgkin Lymphoma-Directed Therapy. Neurologist (IF 1.2) Pub Date : 2023-10-19 Sara J Hooshmand, Karan L Chohan, Aditya Raghunathan, Deborah L Renaud, Michael W Ruff
BRCA1-associated ataxia-telangiectasia-mutated activator-1 (BRAT1) is responsible for cell cycle surveillance and mitochondrial function. The implications of adult-onset BRAT1-variant and the resulting phenotypic neurocognitive and imaging features have not been previously described.
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Reverse Flow Thromboembolism From Distal Subclavian Artery Aneurysm Due to Arterial Thoracic Outlet Syndrome and Posterior Circulation Stroke- Role of Dynamic Doppler Imaging. Neurologist (IF 1.2) Pub Date : 2023-09-22 Adarsh Anil Kumar, Santhosh Kumar Kannath, Bejoy Thomas, Sylaja Pn, Shivanesan P, Manju Surendran
Arterial thoracic outlet syndrome (aTOS) is the least common among the 3 subtypes of thoracic outlet syndrome and can be the cause of posterior circulation infarction due to thrombus from a secondary thrombosed subclavian-axillary artery aneurysm.
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Spinal Meningeal Mass Lesion: A Rare Presentation of Primary Dural Follicular Lymphoma. Neurologist (IF 1.2) Pub Date : 2023-09-14 Jessica D White, Michelle J Clarke, Jonas Paludo, Andrew L Feldman, Ugur T Sener
The differential diagnosis of a spinal intradural extramedullary mass lesion is broad and includes meningioma, schwannoma, neurofibroma, leptomeningeal metastasis, and myxopapillary ependymoma. Though rare, lymphoma should be included in the differential diagnosis of a dural mass lesion.
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Impact of Frailty on Inpatient Outcomes of Acute Traumatic Spinal Cord Injury: Evidence From US National Inpatient Sample. Neurologist (IF 1.2) Pub Date : 2023-09-04 Hongyu Chu, Liang Chen, Jun Li, Jianjun Li, Degang Yang, Mingliang Yang, Liangjie Du, Maoyuan Wang, Feng Gao
Spinal cord injury (SCI) is any spinal cord injury or affliction that results in temporary or permanent impairment of motor or sensory function. This study determined the prevalence of frailty and its impact on in-hospital outcomes of patients admitted with acute traumatic SCI (TSCI).
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Uric Acid Nephropathy Secondary to Generalized Tonic-Clonic Seizures. Neurologist (IF 1.2) Pub Date : 2023-09-04 Amanda Simon, Dan Nguyen, Blake Newman, Amir Arain
Acute kidney injury is a well-known complication of generalized tonic-clonic seizures, most commonly due to rhabdomyolysis. Elevated serum uric acid resulting in uric acid nephropathy is an overlooked cause of acute kidney injury in these patients, with only a few published case reports.
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MR Imaging Patterns and Prognosis in Powassan Virus Encephalitis. Neurologist (IF 1.2) Pub Date : 2023-08-29 Pasquale F Finelli
Powassan virus (POWV) encephalitis is an arbovirus infection and the only tick-borne encephalitis serogroup which is present in mainland North America. The magnetic resonance (MR) imaging described with POWV encephalitis is varied, nonspecific, and limited in number, and as such, imaging patterns and outcomes with this arbovirus infection are not well appreciated.
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The Covert Impact of Chiari Network and Eustachian Valves on Stroke: A Scoping Review and Meta-Analysis. Neurologist (IF 1.2) Pub Date : 2023-08-29 Mohammed Q Al-Sabbagh, Prasanna Eswaradass
The role of Chiari network (CN) and Eustachian valves (EVs) in cardioembolic strokes is still unclear. There is inconsistency in the literature regarding clinical approach to these lesions to reduce stroke risk. We aimed to describe clinical presentation, neuroimaging and cardioimaging features, as well as management approaches for CN and EV in stroke context.
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Neurological Manifestations Induced by Nitrous Oxide Abuse: A Case Series and Review of Literature. Neurologist (IF 1.2) Pub Date : 2023-08-29 Maud Pichon, Loubna Majhadi, Anne-Marie Menn
Nitrous oxide (NO) abuse is increasing among young people. This can result in severe neurological disorders such as myelopathy and/or peripheral neuropathy. We report the clinical presentations, biological, radiologic and electrophysiological findings of 5 patients hospitalized with neurological symptoms consecutive to NO abuse. In addition, a literature review was conducted to describe the neurological
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Stroke Phase Is Essential for Pneumonia in Dysphagia Patients After Cerebral Infarction. Neurologist (IF 1.2) Pub Date : 2023-08-28 Zi Ke, Wei Liu, Fuyan Chen, Wenyi Ge, Yiru Bao, Jian Wen, Yang Liu, Xingping Li, Xiaonong Fan, Bangqi Wu
The risk of pneumonia increases after stroke, especially in poststroke dysphagia patients. Propensity score matching (PSM) is a statistical method in SPSS, which can be used to balance the difference between the 2 groups of known factors. Nasogastric tube feeding is an important factor of stroke-associated pneumonia. However, few studies have used PSM to eliminate the effect of confounding factor.
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Limb-Shaking And Transient Ischemic Attack: A Systematic Review. Neurologist (IF 1.2) Pub Date : 2023-08-25 Jamir Pitton Rissardo, Ana Letícia Fornari Caprara
Limb-shaking is one of the transient ischemic attacks (TIA) 'chameleons.' This literature review aims to evaluate the clinical, epidemiological profile, pathologic mechanisms, and management of limb-shaking TIA.
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Moving From Alteplase to Tenecteplase for Acute Ischemic Stroke-Mayo Clinic Experience. Neurologist (IF 1.2) Pub Date : 2023-08-25 Ahmed Koriesh, Michael Liu, Waleed Brinjikji, James Klaas, Deena Nasr, Zafer Keser
Tenecteplase is a fibrin-specific plasminogen activator that has shown promising results in the treatment of acute ischemic stroke. Tenecteplase has been suggested to reduce door-to-needle time and to increase the rate of spontaneous recanalization. In February 2021, Mayo Clinic Health System switched to Tenecteplase as the standard thrombolytic therapy for acute ischemic stroke.
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The Relationship between Lumbar Puncture Opening Pressure and Retinal Nerve Fiber Layer Thickness in the Diagnosis of Idiopathic Intracranial Hypertension: Is a Lumbar Puncture Always Necessary? Neurologist (IF 1.2) Pub Date : 2023-08-25 Nurhan Kaya Tutar, Nilufer Kale
Idiopathic intracranial hypertension (IIH), is characterized by elevated intracranial pressure (ICP) without an identified cause. Today, lumbar puncture (LP) is the most common method used for diagnosis by measuring cerebrospinal fluid (CSF) pressure to reflect intracranial pressure. This invasive examination has significant disadvantages, such as complications and negative experiences for patients
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C9orf72 Repeat Expansion Initially Presenting as Late-onset Bipolar Disorder With Psychosis. Neurologist (IF 1.2) Pub Date : 2023-08-25 Leslie S Gaynor, Golnaz Yadollahikhales, Elena Tsoy, Matthew Hall, Adam L Boxer, Bruce L Miller, Lea T Grinberg
C9orf72 expansion is the most common genetic abnormality in behavioral variant frontotemporal dementia (bvFTD) and amyotrophic lateral sclerosis. Although psychiatric prodromes are common in C9orf72 expansion carriers, there are only scattered reported cases of primary psychiatric disorders, such as bipolar disorder, diagnosed at disease onset. Moreover, C9orf72 carrier status is rarely identified
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Developing and Validating a New Model to Predict the Risk of Poor Neurological Status of Acute Ischemic Stroke After Intravenous Thrombolysis. Neurologist (IF 1.2) Pub Date : 2023-08-25 Lu Liu, Weiping Wang
The objective of this study was to develop and validate a predictive model for the risk of poor neurological status in in-hospital patients with acute ischemic stroke (AIS) after intravenous thrombolysis.
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Clinical Neurology in Practice: The Tongue (part 2). Neurologist (IF 1.2) Pub Date : 2023-08-25 Stéphane Mathis, Guilhem Solé, Nathalie Damon-Perrière, Marie Rouanet-Larrivière, Fanny Duval, Julia Prigent, Louis Nadal, Yann Péréon, Gwendal Le Masson
The tongue is an essential organ for the development of certain crucial functions such as swallowing and speech. The examination of the tongue can be very useful in neurology, as the various types of lingual alterations can lead to certain specific diagnoses, the tongue being a kind of 'mirror' of some neurological function.
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Clinical Neurology in Practice: The Tongue (Part 1). Neurologist (IF 1.2) Pub Date : 2023-08-25 Stéphane Mathis, Guilhem Solé, Nathalie Damon-Perrière, Marie Rouanet-Larrivière, Fanny Duval, Julia Prigent, Louis Nadal, Yann Péréon, Gwendal Le Masson
The tongue is an essential organ for the development of certain crucial functions, such as swallowing and language. The examination of the tongue can be very useful in neurology, as the various types of lingual alterations can lead to certain specific diagnoses, the tongue being a kind of "mirror" of some neurological function.
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Thrombolysis Versus Nonthrombolyzed in Patients With Mild Strokes and Large Vessel Occlusions: Results of a Multicenter Stroke Registration. Neurologist (IF 1.2) Pub Date : 2023-08-25 Xintong Luo, Tiantian Huo, Pengkai Cao, Jingru Zhao, Yue Zhang, Guojun Tan
The safety and efficacy of intravenous thrombolysis (IVT) in acute ischemic stroke patients with large vessel occlusions and mild neurological deficits are controversial.
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A Case of Cerebral Large-Vessel Vasculitis Concomitant Fahr Syndrome in Systemic Lupus Erythematosus. Neurologist (IF 1.2) Pub Date : 2023-08-25 Wen Jiang, Song Mei, Qionghua Deng, Chunyan Lei, Ailan Pang
Systemic lupus erythematosus (SLE) is a heterogenous, devastating autoimmune inflammatory disease with multiorgan involvement. A variety of neurological and psychiatric symptoms may be caused by nervous system involvement, termed neuropsychiatric systemic lupus erythematosus.
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Focal Cerebral Vasculitis due to SARS-CoV-2 Infection With a Robust Response to Intravenous Steroids. Neurologist (IF 1.2) Pub Date : 2023-08-23 Cleo Zarina Reyes, Manny Villar, Kathryn Cheponis, Hussam A Yacoub
Severe and less common neurological manifestations of SARS-CoV-2 infection include acute ischemic stroke, intracerebral hemorrhage, central venous sinus thrombosis, and vasculitis. In this report, we present a case of a 42-year-old man with acute ischemic stroke due to SARS-CoV-2 infection-associated central nervous system vasculitis that improved with steroid therapy.
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Middle Cerebral Artery Blood Flow Velocity During Normal Pregnancy. Neurologist (IF 1.2) Pub Date : 2023-08-22 Esra Erkoç Ataoğlu, Hale Batur Çağlayan, Bijen Nazliel, Mehmet Çinar, Asli Akyol Gürses, Özlem Moraloğlu Tekin
The present study aimed to evaluate resting middle cerebral artery (MCA) blood flow velocities using transcranial Doppler ultrasound (TCD) in healthy women at different stages of pregnancy, and to compare these velocities with those of normal controls.
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Trends in Antiseizure Medication Prescribing Among Nursing Home Residents With and Without a Seizure Diagnosis. Neurologist (IF 1.2) Pub Date : 2023-08-15 Jonathan D Winter, J William Kerns, Katherine M Winter, Alicia Richards, Roy T Sabo
Evaluate current prevalence and changes in prescribing of antiseizure medications (ASMs) in Virginia nursing homes for residents with and without seizures.
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Safety and Efficacy of Aspiration Catheter CAT6 and 5 Fr Navien in the Endovascular Treatment of Acute Ischemic Stroke. Neurologist (IF 1.2) Pub Date : 2023-08-07 Zhongjun Chen, Tieping Fan, Xusheng Zhao, Teng Hu, Hengxu Qi, Di Li
Mechanical thrombectomy has become a key treatment option for acute ischemic stroke. This study compared the safety and efficacy of aspiration catheter CAT6 and 5 Fr Navien.
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Efficacy and Safety of Human Urinary Kallidinogenase for Acute Ischemic Stroke: A Retrospective Single-Center Study. Neurologist (IF 1.2) Pub Date : 2023-08-03 Ruixian Wang, Yanjun Zhang, Yajuan Shao, Xiujuan Yang, Lei Chen
The aim of this study was to investigate the outcomes of human urinary kallidinogenase (HUK) after recombinant tissue-type plasminogen activator treatment in patients with acute ischemic stroke (AIS).
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Sporadic Creutzfeldt-Jakob Disease Initially Presenting With Posterior Reversible Encephalopathy Syndrome: A Case Report. Neurologist (IF 1.2) Pub Date : 2023-08-02 John P Mikhaiel, Melvin Parasram, Thomas Manning, Mohammed W Al-Dulaimi, Erin C Barnes, Guido J Falcone, David Y Hwang, Morgan L Prust
Sporadic Creutzfeldt-Jakob disease (sCJD) is a fatal neurodegenerative condition caused by prion proteins. Cortical and subcortical diffusion-weighted imaging restriction on magnetic resonance imaging (MRI) is associated with sCJD. Posterior reversible encephalopathy syndrome (PRES) results from impaired vessel autoregulation due to an identifiable trigger, which is associated with subcortical fluid-attenuated
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Recurrent Cerebral Infarction Due to Moyamoya Disease Complicated With Systemic Lupus Erythematosus: A Case Report and Literature Review. Neurologist (IF 1.2) Pub Date : 2023-07-19 Qisong Wang, Qiang Yao, Si Yuan, Yan Shen, Yang Feng, Luji Liu, Yipu Zhu, Yanying Zhao, Junzhao Cui, Jin Qin, Jing Tian, Ruijie Zhao, Lijuan Liu, Yicong Zhou, Xiaoyun Liu
We report a rare case of moyamoya disease caused by an RNF213 mutation, complicated with systemic lupus erythematosus.
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Late-Onset COL4A1 Mutation with Recurrent Ischemic and Hemorrhagic Strokes. Neurologist (IF 1.2) Pub Date : 2023-07-13 Jenny J Lee, Smit Patel, Jason D Hinman
Mutations in type IV collagen gene COL4A1 are identified as a cause of autosomal dominant cerebrovascular disease. We report an unusual late-onset presentation.
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Early Rehabilitation and Nursing Intervention (ERNI) Accelerates the Recovery of Patients With Ischemic Stroke. Neurologist (IF 1.2) Pub Date : 2023-07-13 Jianghua Huang, Juan Zuo, Xuan Tang, Jieqiong Zou, Yahua Zeng, Shuangqin Chen, Gufen He
Ischemic stroke, a severe disease with high disability and mortality, causes an overburden in society and demands more effective treatments. Early rehabilitation and nursing intervention (ERNI) helps the postoperative recovery of patients with hypertensive intracerebral hemorrhage. However, the effect of ERNI on the recovery of people after ischemic stroke remains unclear.
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A Case Report of Migraine With Aura Worsened After Starting Apixaban and Literature Review. Neurologist (IF 1.2) Pub Date : 2023-07-10 Nour Alhayek, Ehab Harahsheh, Oana Dumitrascu, Anthony L Green
Multiple medications have been related to triggering headache attacks or worsening headache frequency or severity in patients with migraine disease. However, the impact of direct oral anticoagulants on headache frequency and severity in patients with migraine disease is unclear. Current literature is scarce and controversial.
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Recurrent Tumefactive Central Nervous System Lesions Due to BRIP1-Related Fanconi Anemia. Neurologist (IF 1.2) Pub Date : 2023-07-07 Nabeela Nathoo, Ralitza H Gavrilova, Jorge A Trejo-Lopez, Patrick W McGarrah, Ronald S Go, Abdulradha Alqallaf, W Oliver Tobin
Fanconi anemia (FA) is an inherited condition associated with genetic mutations that affect DNA repair proteins. More than 20 genes involved in the FA/BRCA pathway have been implicated in FA, including BRIP1. Tumefactive brain lesions are rare in FA.
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Venous Thromboembolism Prophylaxis After Spontaneous Intracerebral Hemorrhage: A Review. Neurologist (IF 1.2) Pub Date : 2023-06-29 Chang Dong, Ying Li, Zhuang Ma Md
Patients with spontaneous intracerebral hemorrhage (sICH) are at high risk for venous thromboembolism (VTE). The administration of mechanical and pharmacological VTE prophylaxis after sICH is important but challenging. The safety and efficacy of the optimal anticoagulant dose, timing, and type of VTE chemoprophylaxis in cases of sICH are still unclear, and clinicians are concerned that it may lead
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Systemic Immune-Inflammation Index is a Prognostic Predictor for Patients With Acute Ischemic Stroke Treated With Intravenous Thrombolysis. Neurologist (IF 1.2) Pub Date : 2023-06-27 Chan-Juan Wei, Juan-Juan Xue, Xiao Zhou, Xiao-Shuang Xia, Xin Li
To investigate whether baseline systemic immune-inflammation index (SII) is associated with 3-month poor prognosis and early neurological outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis.
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Randomized Trial of a Social Support Intervention to Improve Home Blood Pressure Monitoring in Patients With Cerebrovascular Disease. Neurologist (IF 1.2) Pub Date : 2023-06-27 Michael T Mullen, Brett L Cucchiara, Steven R Messé, Ahmad Zamzam, Scott E Kasner
A pilot randomized trial evaluating whether a social support intervention improves adherence to home blood pressure (BP) monitoring among patients with cerebrovascular disease.
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Characteristics and Mechanism of Acute Ischemic Stroke in NAVF Patients With Prior Oral Anticoagulant Therapy. Neurologist (IF 1.2) Pub Date : 2023-06-27 Sufang Xue, Risu Na, Jing Dong, Min Wei, Qi Kong, Qiujia Wang, Xue Qiu, Fangyu Li, Haiqing Song
We aimed to analyze the characteristics and mechanisms of acute ischemic stroke (AIS) in patients with nonvalvular atrial fibrillation (NVAF) who received prior anticoagulant therapy.
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Obesity-hyperlipidemia, Hypertension, and Left Atrial Enlargement During Stroke in Young Adults. Neurologist (IF 1.2) Pub Date : 2023-06-26 Shouye Zhang, Peng Zuo
This study investigated the association between left atrial enlargement and stroke severity in young adults. We also studied the differences between the normal and left atrial enlargement groups in clinical data.
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Efficacy of Urinary Kallidinogenase Plus Intravenous Recombinant Tissue Plasminogen Activator for Stroke Patients With Extended Window: A Retrospective Analysis. Neurologist (IF 1.2) Pub Date : 2023-05-29 Xueyuan Li, Xin Zhang, Ying Yang, Hongzhi Wang, Jingbo Zhang
To assess the outcome of human urinary kallidinogenase (HUK) plus recombinant tissue plasminogen activator (rT-PA) intravenous thrombolysis for stroke patients with an extended time window(4.5 to 9 h).
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"Uncrossed Central Facial Paralysis" Caused by Pontine Infarction: A Case Report. Neurologist (IF 1.2) Pub Date : 2023-05-26 Liwen Zhao, Bingcheng Ren
We report a patient with extraordinary pontine infarction-induced contralateral central facial palsy and weakened limb strength.
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Remote Ischemic Conditioning for Motor Recovery after Acute Ischemic Stroke. Neurologist (IF 1.2) Pub Date : 2023-05-24 Wantong Yu, Changhong Ren, Jubao Du, Wenbo Zhao, Wenting Guo, Xunming Ji
Remote ischemic conditioning (RIC) has shown an impressive neuroprotective effect on acute ischemic stroke (AIS) in animal experiments. But whether chronic RIC improves long-term functional outcomes remains unclear.