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Kappa-opioid receptor stimulation in the nucleus accumbens shell and ethanol drinking: Differential effects by rostro-caudal location and level of drinking Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-25 Breanne E. Pirino, Annie Hawks, Brody A. Carpenter, Pelagia G. Candelas, Andrew T. Gargiulo, Genevieve R. Curtis, Anushree N. Karkhanis, Jessica R. Barson
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Does acute cannabidiol (CBD) use impair performance? A meta-analysis and comparison with placebo and delta-9-tetrahydrocannabinol (THC) Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-25 Lindsay A. Lo, April L. Christiansen, Justin C. Strickland, Carly A. Pistawka, Lauren Eadie, Ryan Vandrey, Caroline A. MacCallum
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Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer’s disease Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-23 Paul Armstrong, Hüseyin Güngör, Pariya Anongjanya, Clare Tweedy, Edward Parkin, Jamie Johnston, Ian M. Carr, Neil Dawson, Steven J. Clapcote
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Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-23 Tsun Hay Jason Ng, Mohammed H. Sarikahya, Roger Hudson, Hanna J. Szkudlarek, Enzo Pérez-Valenzuela, Taygun C. Uzuneser, Emma Proud, Dana Gummerson, Miray Youssef, Madeline Machado, Kuralay Zhaksylyk, Marieka V. DeVuono, Chaochao Chen, Ken K.-C. Yeung, Walter J. Rushlow, Steven R. Laviolette
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Dorsal CA3 overactivation mediates witnessing stress-induced recognition memory deficits in adolescent male mice Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-19 Xiao Liu, Rui Liu, Ya-Xin Sun, Hong-Li Wang, Han Wang, Ting Wang, Yu-Nu Ma, Xue-Xin Li, Qi Wang, Yun-Ai Su, Ji-Tao Li, Tian-Mei Si
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Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1 Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-18 Janina Kupke, Julien Klimmt, Franziska Mudlaff, Maximilian Schwab, Pavlo Lutsik, Christoph Plass, Carsten Sticht, Ana M. M. Oliveira
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Insular cortex subregions have distinct roles in cued heroin seeking after extinction learning and prolonged withdrawal in rats Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-18 Matthew S. McGregor, Caitlin V. Cosme, Ryan T. LaLumiere
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Does steroid increase LPS-induced sickness behaviors? Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-15 Kubra Karadag, Bariscan Cimen, Mert Ertunc, Yildirim Sara
Dear Editor, With respect to Martz’s inspiring article [1] we would like to point out a few results of Martz et al. that we found incomprehensible.
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Reply to Karadag: does steroid increase LPS-induced sickness behaviors? Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-13 Julia Martz, Micah A. Shelton, Laurel Geist, Marianne L. Seney, Amanda C. Kentner
Replying to Martz J et al. Neuropsychopharmacology https://doi.org/10.1038/s41386-024-01838-x (2024) Karadag et al. [1] were concerned that the corticosterone inhibitor, metyrapone, reversed the effect of lipopolysaccharide (LPS) on sickness behavior. While not the focus of our paper, we also find it interesting that maternal sickness responses were decreased in rat dams that received metyrapone and
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Clinical decision support for bipolar depression using large language models Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-13 Roy H. Perlis, Joseph F. Goldberg, Michael J. Ostacher, Christopher D. Schneck
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Elevated dorsal medial prefrontal cortex to lateral habenula pathway activity mediates chronic stress-induced depressive and anxiety-like behaviors Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-13 Xiaohan Tong, Jijin Wu, Ruizhe Sun, Han Li, Yingxi Hong, Xianwei Liu, Ying Sun, Chunxiao Chen, Lu Huang, Song Lin
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Lifespan development of thalamic nuclei and characterizing thalamic nuclei abnormalities in schizophrenia using normative modeling Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-13 Anna S. Huang, Kaidi Kang, Simon Vandekar, Baxter P. Rogers, Stephan Heckers, Neil D. Woodward
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Brain-based graph-theoretical predictive modeling to map the trajectory of anhedonia, impulsivity, and hypomania from the human functional connectome Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-13 Rotem Dan, Alexis E. Whitton, Michael T. Treadway, Ashleigh V. Rutherford, Poornima Kumar, Manon L. Ironside, Roselinde H. Kaiser, Boyu Ren, Diego A. Pizzagalli
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Critical review and recommendations for enhancement of the article on novel neurosteroid therapeutics for postpartum depression Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-12 Tiago Tanimoto Ribeiro, Marisa Bezerra de Araújo, Guilherme Nobre Nogueira, Fabio Gomes de Matos e Souza, Luisa Weber Bisol
The article authored by Patterson et al., titled “Novel neurosteroid therapeutics for postpartum depression: perspectives on clinical trials, program development, active research, and future directions,” published in Volume 49, pages 67–72 (September 15, 2023), provides a comprehensive analysis of the use of novel steroid therapeutics, particularly brexanolone, in patients with postpartum depression
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Late-adolescent onset of prefrontal endocannabinoid control of hippocampal and amygdalar inputs and its impact on trace-fear conditioning behavior Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-11 Hanna M. Molla, Anabel M. M. Miguelez Fernández, Kuei Y. Tseng
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Effect of serum concentrations of IL-6 and TNF-α on brain structure in anorexia nervosa: a combined cross-sectional and longitudinal study Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-09 Fabio Bernardoni, Friederike Tam, David M. Poitz, Inger Hellerhoff, Dominic Arold, Daniel Geisler, Frances Lemme, Johanna Keeler, Kerstin Weidner, Carmine Pariante, Veit Roessner, Joseph A. King, Stefan Ehrlich
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Reactivation of encoding ensembles in the prelimbic cortex supports temporal associations Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-07 Thays Brenner Santos, Cesar Augusto de Oliveira Coelho, Juliana Carlota Kramer-Soares, Paul W. Frankland, Maria Gabriela Menezes Oliveira
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Developmental and molecular contributions to contextual fear memory emergence in mice Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-05 Alexandra L. Lanjewar, Pat Levitt, Kathie L. Eagleson
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Reply to Bisol: Critical review and recommendations for enhancement of the article on novel neurosteroid therapeutics for postpartum depression Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-04 Riah Patterson, Samantha Meltzer-Brody
The U.S. Food and Drug Administration (FDA) approved brexanolone for the treatment of moderate-to-severe postpartum depression (PPD) in March of 2019. Our aim was not to critically review the methodology of the clinical trials or the FDA approval of brexanolone, but instead to provide context for these developments and to comment on the neurosteroid therapeutic landscape as it evolves. Many of Bisol
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Mediodorsal thalamus projection to medial prefrontal cortical mediates social defeat stress-induced depression-like behaviors Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-04 Fang Li, Xuefeng Zheng, Hanjie Wang, Lianghui Meng, Meiying Chen, Yuqing Hui, Danlei Liu, Yifei Li, Keman Xie, Jifeng Zhang, Guoqing Guo
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Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-02 Johanna Seitz-Holland, Yasser Alemán-Gómez, Kang Ik K. Cho, Ofer Pasternak, Martine Cleusix, Raoul Jenni, Philipp S. Baumann, Paul Klauser, Philippe Conus, Patric Hagmann, Kim Q. Do, Marek Kubicki, Daniella Dwir
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Effects of gene dosage and development on subcortical nuclei volumes in individuals with 22q11.2 copy number variations Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-02 Charles H. Schleifer, Kathleen P. O’Hora, Hoki Fung, Jennifer Xu, Taylor-Ann Robinson, Angela S. Wu, Leila Kushan-Wells, Amy Lin, Christopher R. K. Ching, Carrie E. Bearden
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Potential therapeutics for effort-related motivational dysfunction: assessing novel atypical dopamine transport inhibitors Neuropsychopharmacology (IF 7.6) Pub Date : 2024-03-01 Alev Ecevitoglu, Nicolette Meka, Renee A. Rotolo, Gayle A. Edelstein, Sonya Srinath, Kathryn R. Beard, Carla Carratala-Ros, Rose E. Presby, Jianjing Cao, Amarachi Okorom, Amy H. Newman, Mercè Correa, John D. Salamone
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GABA release from central amygdala neurotensin neurons differentially modulates ethanol consumption in male and female mice Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-28 Graydon B. Gereau, María L. Torruella-Suárez, Sarah E. Sizer, Mengfan Xia, Diana Zhou, Luke A. Wykoff, Adonay T. Teklezghi, Ali Alvarez-Pamir, Kristen M. Boyt, Thomas L. Kash, Zoé A. McElligott
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Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-26 Michal Pietrzak, Adam Yngve, J. Paul Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J. Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
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Stimulant medications in children with ADHD normalize the structure of brain regions associated with attention and reward Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-26 Feifei Wu, Wenchao Zhang, Weibin Ji, Yaqi Zhang, Fukun Jiang, Guanya Li, Yang Hu, Xiaorong Wei, Haoyi Wang, Szu-Yung (Ariel) Wang, Peter Manza, Dardo Tomasi, Nora D. Volkow, Xinbo Gao, Gene-Jack Wang, Yi Zhang
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Dissecting the genetic overlap between severe mental disorders and markers of cellular aging: Identification of pleiotropic genes and druggable targets Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-24 Claudia Pisanu, Donatella Congiu, Anna Meloni, Pasquale Paribello, George P. Patrinos, Giovanni Severino, Raffaella Ardau, Caterina Chillotti, Mirko Manchia, Alessio Squassina
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The sinking platform test: a novel paradigm to measure persistence in animal models Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-23 Gabriele Floris, Sean C. Godar, Giulia Braccagni, Ignazio S. Piras, Alicia Ravens, Mary T. Zanda, Matthew J. Huentelman, Marco Bortolato
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Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian randomization approach Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-23 Brenda Cabrera-Mendoza, Necla Aydin, Gabriel R. Fries, Anna R. Docherty, Consuelo Walss-Bass, Renato Polimanti
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A locus coeruleus to dorsal hippocampus pathway mediates cue-induced reinstatement of opioid self-administration in male and female rats Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-19 Tamara Markovic, Jessica Higginbotham, Brian Ruyle, Nicolas Massaly, Hye Jean Yoon, Chao-Cheng Kuo, Jenny R. Kim, Jiwon Yi, Jeniffer J. Garcia, Eric Sze, Julian Abt, Rachel H. Teich, Joanna J. Dearman, Jordan G. McCall, Jose A. Morón
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LC-derived excitatory synaptic transmission to dorsal raphe serotonin neurons is inhibited by activation of alpha2-adrenergic receptors Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-17 Aleigha Gugel, Erik A. Ingebretsen, Holly S. Hake, Stephanie C. Gantz
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Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-16 Anas Reda, Luca A. Hategan, Timothy A. B. McLean, Samantha D. Creighton, Jian Qi Luo, Sean En Si Chen, Shan Hua, Stephen Winston, Isaiah Reeves, Aditya Padmanabhan, Tarkan A. Dahi, Firyal Ramzan, Mark A. Brimble, Patrick J. Murphy, Brandon J. Walters, Gilda Stefanelli, Iva B. Zovkic
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Dynamic and accessible pharmacogenomic results: a response to pharmacogenomic testing for antidepressant treatment selection Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-10 Christina N. Sun, Lucas A. Berenbrok, James M. Stevenson
We thank Drs. Frye and Nemeroff for their perspective on the promising role of pharmacogenetics (PGx) in the selection of antidepressant treatment [1]. In their article, Frye and Nemeroff discuss several challenges to the wide-scale application of PGx for the treatment of depression. We agree that there are several challenges to address, particularly regarding electronic health record (EHR) integration
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Social isolation and aggression training lead to escalated aggression and hypothalamus-pituitary-gonad axis hyperfunction in mice Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-09 Vinícius Elias de Moura Oliveira, Florence Evrard, Melanie C. Faure, Julie Bakker
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White and gray matter alterations in bipolar I and bipolar II disorder subtypes compared with healthy controls – exploring associations with disease course and polygenic risk Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-08 Katharina Thiel, Hannah Lemke, Alexandra Winter, Kira Flinkenflügel, Lena Waltemate, Linda Bonnekoh, Dominik Grotegerd, Katharina Dohm, Tim Hahn, Katharina Förster, Philipp Kanske, Jonathan Repple, Nils Opel, Ronny Redlich, Friederike David, Andreas J. Forstner, Frederike Stein, Katharina Brosch, Florian Thomas-Odenthal, Paula Usemann, Lea Teutenberg, Benjamin Straube, Nina Alexander, Hamidreza Jamalabadi
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tRNA epitranscriptomic alterations associated with opioid-induced reward-seeking and long-term opioid withdrawal in male mice Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-08 Jennifer Blaze, Caleb J. Browne, Rita Futamura, Behnam Javidfar, Venetia Zachariou, Eric J. Nestler, Schahram Akbarian
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Brain connectivity changes to fast versus slow dopamine increases Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-07 Peter Manza, Dardo Tomasi, Leah Vines, Diana Sotelo, Michele-Vera Yonga, Gene-Jack Wang, Nora D. Volkow
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Two polygenic mouse models of major depressive disorders identify TMEM161B as a potential biomarker of disease in humans Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-07 Malika El Yacoubi, Claire Altersitz, Violaine Latapie, Elari Rizkallah, Sébastien Arthaud, Laure Bougarel, Marcela Pereira, Anne Wierinckx, Wissam El-Hage, Raoul Belzeaux, Gustavo Turecki, Per Svenningsson, Benoît Martin, Joël Lachuer, Jean-Marie Vaugeois, Stéphane Jamain
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Stress integration by an ascending adrenergic-melanocortin circuit Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-07 Connor Laule, Nilufer Sayar-Atasoy, Iltan Aklan, Hyojin Kim, Tayfun Ates, Debbie Davis, Deniz Atasoy
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Network-based drug repurposing for schizophrenia Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-06 Trang T. T. Truong, Zoe S. J. Liu, Bruna Panizzutti, Jee Hyun Kim, Olivia M. Dean, Michael Berk, Ken Walder
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Identifying novel proteins for suicide attempt by integrating proteomes from brain and blood with genome-wide association data Neuropsychopharmacology (IF 7.6) Pub Date : 2024-02-05 Hao Zhao, Yifeng Liu, Xuening Zhang, Yuhua Liao, Huimin Zhang, Xue Han, Lan Guo, Beifang Fan, Wanxin Wang, Ciyong Lu
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Heartbeat-evoked neural response abnormalities in generalized anxiety disorder during peripheral adrenergic stimulation Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-30 Charles Verdonk, Adam R. Teed, Evan J. White, Xi Ren, Jennifer L. Stewart, Martin P. Paulus, Sahib S. Khalsa
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Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-29 Conor H. Murray, Joel Frohlich, Connor J. Haggarty, Ilaria Tare, Royce Lee, Harriet de Wit
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Data-driven connectivity profiles relate to smoking cessation outcomes Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-27 Laura Murray, Blaise B. Frederick, Amy C. Janes
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Reproducible stability of verbal and spatial functions along the menstrual cycle Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-24 Belinda Pletzer, Hannah Bodenbach, Marcel Hoehn, Linda Hajdari, Tobias Hausinger, Isabel Noachtar, Adriene M. Beltz
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Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-17 Justin J. Botterill, Abdessattar Khlaifia, Ryan Appings, Jennifer Wilkin, Francesca Violi, Hanista Premachandran, Arely Cruz-Sanchez, Anna Elisabete Canella, Ashutosh Patel, S. Danyal Zaidi, Maithe Arruda-Carvalho
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Comparison of brain nicotine accumulation from traditional combustible cigarettes and electronic cigarettes with different formulations Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-15 Yantao Zuo, Kiran Kumar Solingapuram Sai, Aeva Jazic, Avinash H. Bansode, Jed E. Rose, Alexey G. Mukhin
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Sex-specific resting state brain network dynamics in patients with major depressive disorder Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-13 Daifeng Dong, Diego A. Pizzagalli, Thomas A. W. Bolton, Maria Ironside, Xiaocui Zhang, Chuting Li, Xiaoqiang Sun, Ge Xiong, Chang Cheng, Xiang Wang, Shuqiao Yao, Emily L. Belleau
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Effects of open access publishing on article metrics in Neuropsychopharmacology Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-11 Briana K. Chen, Taylor Custis, Lisa M. Monteggia, Tony P. George
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Antidepressant-like effects of psychedelics in a chronic despair mouse model: is the 5-HT2A receptor the unique player? Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-11 Mehdi Sekssaoui, Joël Bockaert, Philippe Marin, Carine Bécamel
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Amplitude-determined seizure-threshold, electric field modeling, and electroconvulsive therapy antidepressant and cognitive outcomes Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-11 Christopher C. Abbott, Jeremy Miller, Danielle Farrar, Miklos Argyelan, Megan Lloyd, Taylor Squillaci, Brian Kimbrell, Sephira Ryman, Thomas R. Jones, Joel Upston, Davin K. Quinn, Angel V. Peterchev, Erik Erhardt, Abhishek Datta, Shawn M. McClintock, Zhi-De Deng
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Pharmacokinetic-pharmacodynamic analysis of drug liking blockade by buprenorphine subcutaneous depot (CAM2038) in participants with opioid use disorder Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-10 Sharon L. Walsh, Sandra D. Comer, Jurij Aguiar Zdovc, Céline Sarr, Marcus Björnsson, Kerstin Strandgården, Peter Hjelmström, Fredrik Tiberg
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Neurogenesis-independent mechanisms of MRI-detectable hippocampal volume increase following electroconvulsive stimulation Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-09 Yoshifumi Abe, Kiichi Yokoyama, Tomonobu Kato, Sho Yagishita, Kenji F. Tanaka, Akihiro Takamiya
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Advances in precision neuromodulation: electroconvulsive therapy amplitude titration Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-09 Paul E. Croarkin, Alexander Opitz
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Academic ethics of mental health: the national black postdocs framework for the addressment of support for undergraduate and graduate trainees Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-08 Cellas A. Hayes, Almarely L. Berrios-Negron, Tigist Tamir, Keisha N. Hardeman, Frankie D. Heyward
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Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-06 Elise Koch, Anders Kämpe, Maris Alver, Sindri Sigurðarson, Guðmundur Einarsson, Juulia Partanen, Robert L. Smith, Piotr Jaholkowski, Heidi Taipale, Markku Lähteenvuo, Nils Eiel Steen, Olav B. Smeland, Srdjan Djurovic, Espen Molden, Engilbert Sigurdsson, Hreinn Stefánsson, Kári Stefánsson, Aarno Palotie, Lili Milani, Kevin S. O’Connell, Ole A. Andreassen
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Comparative rhythmic transcriptome profiling of human and mouse striatal subregions Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-05 Kaitlyn A. Petersen, Wei Zong, Lauren M. Depoy, Madeline R. Scott, Vaishnavi G. Shankar, Jennifer N. Burns, Allison J. Cerwensky, Sam-Moon Kim, Kyle D. Ketchesin, George C. Tseng, Colleen A. McClung
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Modulation of learning safety signals by acute stress: paraventricular thalamus and prefrontal inhibition Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-05 Zongliang Wang, Zeyi Wang, Qiang Zhou
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GM-1020: a novel, orally bioavailable NMDA receptor antagonist with rapid and robust antidepressant-like effects at well-tolerated doses in rodents Neuropsychopharmacology (IF 7.6) Pub Date : 2024-01-04 Adam K. Klein, Eric W. Austin, Michael J. Cunningham, Dino Dvorak, Silvia Gatti, Sarah K. Hulls, Laszlo Kiss, Andrew C. Kruegel, Gerard J. Marek, Mariusz Papp, Jonathan Sporn, Zoë A. Hughes
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Acetylcholine muscarinic M1 receptors in the rodent prefrontal cortex modulate cognitive abilities to establish social hierarchy Neuropsychopharmacology (IF 7.6) Pub Date : 2023-12-22 Wen-Jun Chen, Hao Chen, Zi-Ming Li, Wei-Yuan Huang, Jian-Lin Wu