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Neural correlates of increased alcohol demand following alcohol cue exposure in adult heavy drinkers Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-03-23 Michael Amlung, Emma Marsden, Tegan Hargreaves, Lawrence H. Sweet, James G. Murphy, James MacKillop
Alcohol use disorder is associated with overvaluation of alcohol relative to other rewards, in part due to dynamic increases in value in response to alcohol-related cues. In a neuroeconomic framework, alcohol cues increase behavioral economic demand for alcohol, but the neural correlates these cue effects are unknown. This functional magnetic resonance imaging study combined a neuroeconomic alcohol
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Alterations of the amplitude of low-frequency fluctuation induced by repetitive transcranial magnetic stimulation combined with antidepressants treatment for major depressive disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-03-13 Jing Qiu, Weiguo Gu, Yuan Zhang, Lei Wang, Junkang Shen
We investigated the neuroimaging changes and clinical efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with antidepressants in major depressive disorder (MDD) patients. We scanned 35 patients with MDD and 27 healthy controls (HC) with resting-state functional magnetic resonance imaging (fMRI) before and after treatment. We analyzed amplitude of low-frequency fluctuation (ALFF)
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Amygdala functional connectivity in borderline personality disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-03-11 Laila Noor, Jonas Hoffmann, Tina Meller, Christian Gaser, Igor Nenadić
Borderline personality disorder (BPD) is characterised by structural and functional brain alterations. Yet, there is little data on functional connectivity (FC) across different levels of brain networks and parameters. In this study, we applied a multi-level approach to analyse abnormal functional connectivity. We analysed resting-state functional magnetic resonance imaging (fMRI) data sets of 69 subjects:
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Subcortical-cortical white matter connectivity in adults with autism spectrum disorder and schizophrenia patients Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-03-07 Akila Weerasekera, Adrian Ion-Mărgineanu, Garry P. Nolan, Maria Mody
Autism spectrum disorder (ASD) and schizophrenia (SZ) are neuropsychiatric disorders that overlap in symptoms associated with social-cognitive impairment. Alterations of the cingulate cortex, subcortical, medial-temporal, and orbitofrontal structures are frequently reported in both disorders. In this study, we examined white-matter connectivity between these structures in adults with ASD and SZ patients
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Increased extra-neurite conductivity of brain in patients with Alzheimer's disease: A pilot study Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-03-05 Seowon Hong, Yunjeong Choi, Mun Bae Lee, Hak Young Rhee, Soonchan Park, Chang-Woo Ryu, Ah Rang Cho, Oh In Kwon, Geon-Ho Jahng
The objectives of this study were to investigate how the extra-neurite conductivity (EC) and intra-neurite conductivity (IC) were reflected in Alzheimer's disease (AD) patients compared with old cognitively normal (CN) people and patients with amnestic mild cognitive impairment (MCI) and to evaluate the association between those conductivity values and cognitive decline. To do this, high-frequency
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Childhood adversity modulates structural brain changes in borderline personality but not in major depression disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-03-01 Vicente Camacho-Téllez, Mariana N. Castro, Agustina E. Wainsztein, Ximena Goldberg, Gabriela De Pino, Elsa Y. Costanzo, Narcís Cardoner, José M. Menchón, Carles Soriano-Mas, Salvador M. Guinjoan, Mirta F. Villarreal
Adverse childhood experiences (ACEs) negatively affect the function and structure of emotion brain circuits, increasing the risk of various psychiatric disorders. It is unclear if ACEs show disorder specificity with respect to their effects on brain structure. We aimed to investigate whether the structural brain effects of ACEs differ between patients with major depression (MDD) and borderline personality
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The importance of covert memory consolidation in schizophrenia: Dysfunctional network profiles of the hippocampus and the dorsolateral prefrontal cortex Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-02-29 Elias A. Samona, Asadur Chowdury, John Kopchick, Patricia Thomas, Usha Rajan, Dalal Khatib, Caroline Zajac-Benitez, Alireza Amirsadri, Luay Haddad, Jeffrey A. Stanley, Vaibhav A. Diwadkar
Altered brain network profiles in schizophrenia (SCZ) during memory consolidation are typically observed during task- periods such as encoding or retrieval. However active processes are also sub served by periods of memory consolidation. These periods active in that they allow memories to be recapitulated even in the absence of overt sensorimotor processing. It is plausible that regions central to
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Alterations in cortical thickness of frontoparietal regions in patients with social anxiety disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-02-27 Dasom Lee, Ye-Ha Jung, Suhyun Kim, Yoonji Irene Lee, Jeonghun Ku, Uicheul Yoon, Soo-Hee Choi
Although functional changes of the frontal and (para)limbic area for emotional hyper-reactivity and emotional dysregulation are well documented in social anxiety disorder (SAD), prior studies on structural changes have shown mixed results. This study aimed to identify differences in cortical thickness between SAD and healthy controls (CON). Thirty-five patients with SAD and forty-two matched CON underwent
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Abnormal functional connectivity of the intrinsic networks in adolescent bipolar I versus bipolar II disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-02-23 Qian Xiao, Gui Zhang, Yuan Zhong
Background: The symptoms of pediatric bipolar disorder (PBD)-I and PBD-II differ, but accurate identification at an early stage is difficult and may prevent effective treatment of this disorder. Therefore, it is urgent to elucidate a biological marker based on objective imaging indicators to help distinguish the two. Therefore, this research aims to compare the functional connectivity between PBD-I
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Advances in DTI Studies for Diagnoses and Treatment of Obsessive-Compulsive Disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-02-15 Sadegh Masjoodi, MajidReza Farrokhi, Behrouz Vejdani Afkham, Javad Sheikhi Koohsar
This review summarizes the current state of neuroimaging research on obsessive-compulsive disorder (OCD) using diffusion tensor imaging (DTI), which allows for the examination of white matter abnormalities in the brain. DTI studies on individuals with obsessive-compulsive disorder (OCD) consistently demonstrate widespread reductions in white matter integrity in various regions of the brain, including
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Associations of depression and perceived physical fatigability with white matter integrity in older adults Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-02-10 Chemin Lin, Fang‐Cheng Yeh, Nancy W. Glynn, Theresa Gmelin, Yi-Chia Wei, Yao-Liang Chen, Chih-Mao Huang, Yu-Chiau Shyu, Chih-Ken Chen
Fatigability is prevalent in older adults. However, it is often associated with depressed mood. We aim to investigate these two psychobehavioral constructs by examining their underpinning of white matter structures in the brain and their associations with different medical conditions. Twenty-seven older adults with late-life depression (LLD) and 34 cognitively normal controls (CN) underwent multi-shell
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Transdiagnostic symptom of depression and anxiety associated with reduced gray matter volume in prefrontal cortex Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-02-10 Anna C. Cichocki, Richard E. Zinbarg, Michelle G. Craske, Iris K.-Y. Chat, Katherine S. Young, Susan Y. Bookheimer, Robin Nusslock
Dimensional models of psychopathology may provide insight into mechanisms underlying comorbid depression and anxiety and improve specificity and sensitivity of neuroanatomical findings. The present study is the first to examine neural structure alterations using the empirically derived Tri-level Model. Depression and anxiety symptoms of 269 young adults were assessed using the Tri-level Model dimensions:
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Neuroanatomical comparison of treatment-resistant and treatment-responsive schizophrenia patients using the Cloud-Based Brain Magnetic Resonance Image Segmentation and Parcellation system: An MRIcloud study Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-30 Esra Porgalı Zayman, Mehmet Fatih Erbay
Recent developments in neuroimaging have improved our understanding of the biological mechanisms underlying schizophrenia. However, neuroimaging findings in treatment-resistant schizophrenia (TRS) remain unclear. In the present study, we aimed to explore potential neuroanatomical regions that may be associated with treatment resistance in schizophrenia patients by comparing neuroanatomical regions
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The contribution of first-episode illness characteristics and cumulative antipsychotic usage to progressive structural brain changes over a long-term follow-up in schizophrenia Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-29 Tuomas Konttajärvi, Marianne Haapea, Sanna Huhtaniska, Lassi Björnholm, Jouko Miettunen, Matti Isohanni, Matti Penttilä, Graham K. Murray, Hannu Koponen, Anthony C. Vernon, Erika Jääskeläinen, Johannes Lieslehto
Exposure to antipsychotics as well as certain first-episode illness characteristics have been associated with greater gray matter (GM) deficits in the early phase of schizophrenia. Whether the first-episode illness characteristics affect the long-term progression of the structural brain changes remain unexplored. We therefore assessed the role of first-episode illness characteristics and life-time
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Modulating the default mode network: Antidepressant efficacy of transcutaneous electrical cranial-auricular acupoints stimulation targeting the insula Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-26 Ma Yue, Xu Peng, Guo Chunlei, Luo Yi, Gao Shanshan, Sun Jifei, Chen Qingyan, Zhenjun Bai, Liu Yong, Zhang Zhangjin, Rong Peijing, Fang Jiliang
Background Transcutaneous electrical cranial-auricular acupoint stimulation (TECAS) is a novel non-invasive therapy for major depressive disorder (MDD) that stimulates acupoints innervated by the trigeminal and auricular vagus nerves. However, there are few neuroimaging studies involving the TECAS for the treatment of MDD. Therefore, this study aimed to investigate the treatment response and neurological
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Changed brain entropy and functional connectivity patterns induced by electroconvulsive therapy in majoy depression disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-26 Siyu Fan, Jiahua Zhang, Yue Wu, Yue Yu, Hao Zheng, Yuan yuan Guo, Yang Ji, Xiaonan Pang, Yanghua Tian
Objective Our objective is to innovatively integrate both linear and nonlinear characteristics of brain signals in Electroconvulsive Therapy (ECT) research, with the goal of uncovering deeper insights into the pathogenesis of Major Depressive Disorder (MDD) and identifying novel targets for other physical intervention therapies. Methods We measured brain entropy (BEN) in 42 MDD patients and 42 matched
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Neuromelanin-sensitive Magnetic Resonance Imaging in the study of Mental disorder: A systematic review Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-26 Qiuyu Lv, Xuanyi Wang, Pan Lin, Xiang Wang
Dopamine and norepinephrine are implicated in the pathophysiology of mental disorders, but non-invasive study of their neuronal function remains challenging. Recent research suggests that neuromelanin-sensitive magnetic resonance imaging (NM-MRI) techniques may overcome this limitation by enabling the non-invasive imaging of the substantia nigra (SN)/ ventral tegmental area (VTA) dopaminergic and locus
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Neurofeedback for alcohol addiction: Changes in resting state network activity✰ Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-24 B Sanader Vukadinovic, S Karch, M Paolini, P Reidler, B Rauchmann, G Koller, O Pogarell, D Keeser
Alcohol dependence continues to be a major global burden despite significant research progress and treatment development. The aim of this study was to investigate whether neurofeedback training can alter resting state fMRI activity in brain regions that play a crucial role in addiction disorders in patients with alcohol dependence. For this purpose, a total of 52 patients were recruited for the present
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Amygdala biomarkers of treatment response in major depressive disorder: An fMRI systematic review of SSRI antidepressants Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2024-01-03 Vanessa K. Tassone, Fatemeh Gholamali Nezhad, Ilya Demchenko, Alice Rueda, Venkat Bhat
Functional neuroimaging studies have demonstrated abnormal activity and functional connectivity (FC) of the amygdala among individuals with major depressive disorder (MDD), which may be rectified with selective serotonin reuptake inhibitor (SSRI) treatment. This systematic review aimed to identify changes in the amygdala on functional magnetic resonance imaging (fMRI) scans among individuals with MDD
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Electroconvulsive therapy enhances degree centrality in the orbitofrontal cortex in depressive rumination Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-12-12 Hongping Wang, Ting Zhang, Meidan Zu, Siyu Fan, Yiao Kai, Jiahua Zhang, Yang Ji, Xiaonan Pang, Yanghua Tian
Depressive rumination has been implicated in the onset, duration, and treatment response of refractory depression. Electroconvulsive therapy (ECT) is remarkably effective in treatment of refractory depression by modulating the functional coordination between brain hubs. However, the mechanisms by which ECT regulates depressive rumination remain unsolved. We investigated degree centrality (DC) in 32
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New portable device for an examination of visual cognitive evoked potentials might extend their diagnostic applications in psychiatry Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-12-15 Miroslav Kuba, Jan Kremláček, František Vít, Jiří Masopust, Jan Hubeňák, Zuzana Kubová, Jana Szanyi, Lenka Ramešová, Marie Chutná, Jana Langrová
Despite positive prior results obtained by using event-related potentials (ERPs) in psychiatric patients, they are not routinely used in the clinical setting. This may in part be due to problems regarding a lack of transportable equipment availability. It can be difficult for these patients to repeatedly visit electrophysiological laboratories. To address this issue, we propose using a new, fully portable
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Resting-state fMRI is associated with trauma experiences, mood and psychosis in Afro-descendants with bipolar disorder and schizophrenia Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-12-12 Mariélia B.L. de Freitas, Licia P. Luna, Márcia Beatriz, Romulo Kunrath Pinto, Candida H. Lopes Alves, Lays Bittencourt, Antônio E. Nardi, Viola Oertel, André B. Veras, David Freitas de Lucena, Gilberto Sousa Alves
Background Bipolar disorder (BD) and schizophrenia (SCZ) may exhibit functional abnormalities in several brain areas, including the medial temporal and prefrontal cortex and hippocampus; however, a less explored topic is how brain connectivity is linked to premorbid trauma experiences and clinical features in non-Caucasian samples of SCZ and BD. Methods: Sixty-two individuals with SCZ (n=20), BD (n=21)
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Resting-state EEG connectivity recorded before and after rTMS treatment in patients with treatment-resistant depression Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-12-13 Kate Godfrey, Suresh D. Muthukumaraswamy, Cathy M. Stinear, Nicholas R. Hoeh
Repetitive transcranial magnetic stimulation (rTMS) has shown efficacy and tolerability in Major Depressive Disorder (MDD). However, the underlying mechanisms of its antidepressant effects remain unclear. This open-label study investigated electroencephalography (EEG) functional connectivity markers associated with response and the antidepressant effects of rTMS. Resting-state EEG data were collected
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Abnormal caudate nucleus activity in patients with depressive disorder: Meta-analysis of task-based functional magnetic resonance imaging studies with behavioral domain Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-12-12 Jiajia Zhang, Xin Wu, Yajing Si, Yahui Liu, Xueke Wang, Yibo Geng, Qiaohua Chang, Xiaoxiao Jiang, Hongxing Zhang
During task-based functional magnetic resonance imaging (t-fMRI) patients with depressive disorder (DD) have shown abnormal caudate nucleus activation. There have been no meta-analyses that are conducted on the caudate nucleus using Activation Likelihood Estimation (ALE) in patients with DD, and the relationships between abnormal caudate activity and different behavior domains in patients with DD remain
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Effects of Cortisol Administration on Resting-State Functional Connectivity in Women with Depression Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-26 Adam Runyan, Alexis Cassani, Leah Reyna, Erin C. Walsh, Roxanne M. Hoks, Rasmus M. Birn, Heather C. Abercrombie, Carissa L. Philippi
Previous resting-state functional connectivity (rsFC) research has identified several brain networks impacted by depression and cortisol, including default mode (DMN), frontoparietal (FPN), and salience networks (SN). In the present study, we examined the effects of cortisol administration on rsFC of these networks in individuals varying in depression history and severity. We collected resting-state
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Hyperconnecitivity between dorsal attention and frontoparietal networks predicts treatment response in obsessive-compulsive disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-23 Hasan Bakay, Cigdem Ulasoglu-Yildiz, Elif Kurt, Tamer Demiralp, Raşit Tükel
Obsessive-compulsive disorder (OCD) presented with repetitive obsessions and/or compulsions were associated with disrupted resting-state functional connectivity (rs-FC). To investigate the pharmacological treatment effect on rs-FC changes in OCD patients we conducted the seed-to-voxel FC analyses using dorsal attention network (DAN), default mode network (DMN), salience network (SN) and frontoparietal
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Higher Blood-brain barrier permeability in patients with major depressive disorder identified by DCE-MRI imaging Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-23 Binli Shang, Ting Wang, Shilun Zhao, Shu Yi, Tianhao Zhang, Yifan Yang, Fengrui Zhang, Dafu Zhang, Xiufeng Xu, Jian Xu, Baoci Shan, Yuqi Cheng
Background Studies from animal models and clinical trials of blood and cerebrospinal fluid have proposed that blood-brain barrier (BBB) dysfunction in depression (MDD). But there are no In vivo proves focused on BBB dysfunction in MDD patients. The present study aimed to identify whether there was abnormal BBB permeability, as well as the association with clinical status in MDD patients using dynamic
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Non-linear processing and reinforcement learning to predict rTMS treatment response in depression Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-23 Elias Ebrahimzadeh, Amin Dehghani, Mostafa Asgarinejad, Hamid Soltanian-Zadeh
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Relationship between abnormal intrinsic functional connectivity of subcortices and autism symptoms in high-functioning adults with autism spectrum disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-23 Jing Shang, Erwei Shen, Yang Yu, Aiying Jin, Xuemei Wang, Dehui Xiang
Purpose This study explores subcortices and their intrinsic functional connectivity (iFC) in autism spectrum disorder (ASD) adults and investigates their relationship with clinical severity. Methods Resting-state functional magnetic resonance imaging (rs-fMRI) data were acquired from 74 ASD patients, and 63 gender and age-matched typically developing (TD) adults. Independent component analysis (ICA)
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Impact of hypomanic personality traits on brain functional connectivity during a dynamic theory-of-mind task Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-22 Delphine Raucher-Chéné, Audrey Henry, Alexandre Obert, Martina Traykova, Ksenija Vucurovic, Pamela Gobin, Sarah Barrière, Christophe Portefaix, Fabien Gierski, Stéphanie Caillies, Arthur Kaladjian
Hypomanic personality traits are present in the general population and represent a risk factor for developing bipolar disorder. This personality style, notably its social component, is linked to difficulties in theory of mind (i.e., ability to infer mental states). Exploring the neural correlates of mental states’ inference in individuals with these personality traits can provide meaningful insights
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Aberrant dynamic and static functional connectivity of the striatum across specific low-frequency bands in patients with autism spectrum disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-10 Junsa Zhu, Yun Jiao, Ran Chen, Xun-Heng Wang, Yunyan Han
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40-Hz auditory steady-state response deficits are correlated with the severity of persistent auditory verbal hallucination in patients with schizophrenia Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-07 Shaobing Li, Ruxin Hu, Huiming Yan, Lijun Chu, Yuying Qiu, Ying Gao, Meijuan Li, Jie Li
Background Abnormal 40 Hz auditory steady-state response (ASSR) has been observed in some psychiatric disorders. Nevertheless, the role of 40 Hz ASSR in persistent auditory verbal hallucinations (pAVHs) schizophrenia (SCZ) is still unknown. This study aims to investigate whether the 40 Hz ASSR impairment is related to pAVHs and can detect pAVHs severity. Methods We analyzed high-density electroencephalography
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The effect of SARS-CoV-2 virus on resting-state functional connectivity during adolescence: Investigating brain correlates of psychotic-like experiences and SARS-CoV-2 related inflammation response Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-05 Helin Yilmaz Kafali, Hacer Dasgin, Didenur Sahin Cevik, Sara Sinem Sozan, Kader K. Oguz, Müge Mutlu, Aslinur Ozkaya Parlakay, Timothea Toulopoulou
We first aimed to investigate resting-state functional connectivity (rs-FC) differences between adolescents exposed to SARS-CoV-2 and healthy controls. Secondly, the moderator effect of PLEs on group differences in rs-FC was examined. Thirdly, brain correlates of inflammation response during acute SARS-CoV-2 infection were investigated. Eighty-two participants aged between 14 and 24 years (SARS-CoV-2
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Volume changes of the subcortical limbic structures in major depressive disorder patients with and without anhedonia Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-04 Qingli Mu, Dong Cui, Kejing Zhang, Yanghua Ru, Congchong Wu, Zhe Fang, Lili Jia, Shaohua Hu, Manli Huang, Shaojia Lu
Anhedonia is a core feature of major depressive disorder (MDD) and the limbic system has been indicated to be associated with anhedonia in MDD due to its crucial role within the reward circuit. However, the relationship between different regions of the limbic system and MDD, particularly anhedonic symptoms, remains unclear. Therefore, the purpose of this study was to investigate volume changes of various
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Neural correlates of mental state decoding and mental state reasoning in schizophrenia Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-04 Cemal Demirlek, Merve Karakılıç, Ecenaz Sarıkaya, Adem Bayrakçı, Burcu Verim, Funda Gülyüksel, Berna Yalınçetin, Elif Oral, Fazıl Gelal, Nabi Zorlu, Emre Bora
Theory of mind skills are disrupted in schizophrenia. However, various theory of mind tasks measure different neurocognitive domains. This multimodal neuroimaging study aimed to investigate the neuroanatomical correlates of mental state decoding and reasoning components of theory of mind in schizophrenia and healthy controls (HCs) using T1-weighted and diffusion-weighted (DTI) magnetic resonance imaging
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Relationships between GABA, glutamate, and GABA/glutamate and social and olfactory processing in children with autism spectrum disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-11-04 Allegra J. Johnson, Eric Shankland, Todd Richards, Neva Corrigan, Dennis Shusterman, Richard Edden, Annette Estes, Tanya St. John, Stephen Dager, Natalia M. Kleinhans
Theories of altered inhibitory/excitatory signaling in autism spectrum disorder (ASD) suggest that gamma amino butyric acid (GABA) and glutamate (Glu) abnormalities may underlie social and sensory challenges in ASD. Magnetic resonance spectroscopy was used to measure Glu and GABA+ levels in the amygdala-hippocampus region and cerebellum in autistic children (n = 30), a clinical control group with sensory
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Fibre-specific white matter changes in anorexia nervosa Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-27 Feliberto de la Cruz, Andy Schumann, Katrin Rieger, Monica Di Giuliano, Karl-Jürgen Bär
A large body of literature exists on white matter (WM) abnormalities in individuals with anorexia nervosa (AN). However, these studies have primarily relied on the diffusion tensor imaging (DTI), a technique known for its limited ability to resolve complex WM fibre arrangements. To overcome limitations of DTI, this study employed fixel-based analysis (FBA) to investigate fibre-specific WM abnormalities
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Effective connectivity analysis of verbal working memory advantage across materials for pathological smartphone users by fNIRS Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-19 Wenxin Guo, Wei Zhang, Jianli Zhang, Ziyi Li, Wanling Zhu
Previous studies have found working memory (WM) advantages of the pathological smartphone use (PSU) group, but most of which were emphasized in the network-related domain. Whether the advantages can transfer to other domains has yet to be confirmed. In particular, exploring from a brain mechanism perspective is necessary. Using the classical N-back paradigm, this study selected network-related words
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The effects of cocaine use severity and abstinence on behavioral performance and neural processes of response inhibition Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-20 Guangfei Li, Zhao Zhang, Yihe Zhang, Xiaoying Tang, Chiang-Shan R. Li
Previous studies identified cerebral markers of response inhibition dysfunction in cocaine dependence. However, whether deficits in response inhibition vary with the severity of cocaine use or ameliorate during abstinence remain unclear. This study aimed to address these issues and the neural mechanisms supporting the individual variation. We examined the data of 67 individuals with cocaine dependence
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Sleep-related regions in neurodegenerative diseases by central nervous system localization using magnetic resonance imaging Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-20 Sana Mohammadi, Mahdi Mohammadi, Sadegh Ghaderi
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A preliminary investigation into cortical structural alterations in adolescents with nonsuicidal self-injury Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-20 Kinjal K. Patel, Margaret A. Sheridan, Adrienne S. Bonar, Matteo Giletta, Paul D. Hastings, Matthew K. Nock, Karen D. Rudolph, George M. Slavich, Mitchell J. Prinstein, Adam Bryant Miller
The structural neural correlates underlying youth nonsuicidal self-injury (NSSI) warrant further exploration. Few studies have explored the association between NSSI and brain structure in adolescence, and no studies have investigated differences in the relation between age and brain structure in youth with NSSI. This preliminary investigation examined associations between NSSI history, age, and cortical
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Regional Homogeneity in schizophrenia patients with tardive dyskinesia: a resting-state fMRI study Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-18 Ting Yu, Yanli Li, Na Li, Junchao Huang, Fengmei Fan, Xingguang Luo, Shuping Tan, Fude Yang, Baopeng Tian, Li Tian, Chiang-Shan R. Li, Yunlong Tan
Neuronal degeneration and apoptosis may play an important role in the pathogenesis of tardive dyskinesia (TD). Previous studies suggested brain structural and functional abnormalities in patients with TD. We investigated changes in cerebral regional homogeneity (ReHo) in patients with TD using resting-state functional magnetic resonance imaging (rs-fMRI). Imaging data were collected from schizophrenia
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Brain activation during fear extinction recall in unmedicated patients with obsessive-compulsive disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-19 Juliana Belo Diniz, Paulo Rodrigo Bazán, Carlos Alberto de Bragança Pereira, Erlandson Ferreira Saraiva, Paula Roberta Camargo Ramos, Amanda Ribeiro de Oliveira, Adriano Edgar Reimer, Marcelo Queiroz Hoexter, Euripedes Constantino Miguel, Roseli Gedanke Shavitt, Marcelo Camargo Batistuzzo
Specific brain activation patterns during fear conditioning and the recall of previously extinguished fear responses have been associated with obsessive-compulsive disorder (OCD). However, further replication studies are necessary. We measured skin-conductance response and blood oxygenation level-dependent responses in unmedicated adult patients with OCD (n = 27) and healthy participants (n = 22) submitted
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Study of structural network connectivity using DTI tractography in insomnia disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-19 Masoumeh Rostampour, Zeinab Gharaylou, Ali Rostampour, Fatemeh Shahbodaghy, Mojtaba Zarei, Reza Fadaei, Habibolah Khazaie
Most of tractography studies on insomnia disorder (ID) have reported decreased structural connectivity between cortical and subcortical structures. Tractography based on standard diffusion tensor imaging (DTI) can generate high number of false-positive streamlines connections between gray matter regions. In the present study, we employed the convex optimization modeling for microstructure informed
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ROI-based analysis of diffusion indices in healthy subjects and subjects with deficit or non-deficit syndrome schizophrenia Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-18 Yaşar Türk, İsmail Devecioğlu, Atakan Küskün, Cem Öge, Elmas Beyazyüz, Yakup Albayrak
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A novel diagnosis method for schizophrenia based on globus pallidus data Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-18 Olga Bayar Kapici, Yaşar Kapici, Atilla Tekın, Mehmet Şırık
This research aims to diagnose schizophrenia with machine learning-based algorithms. Bayesian neural network, logistic regression, decision tree, k-nearest neighbor, and gaussian kernel classification techniques are investigated to diagnose schizophrenia with data from 125 persons. This study showed that left lateral ventricles and left globus pallidus volumes and their percentages in the brain were
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Major Depression and the Perception of Affective Instrumental and Expressive Gestures: An fMRI Investigation Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-18 Mathilde Sijtsma, Dominic Marjoram, Helen L. Gallagher, Madeleine A. Grealy, David Brennan, Christopher Mathias, Jonathan Cavanagh, Frank E. Pollick
Major depressive disorder (MDD) is associated with biased perception of human movement. Gesture is important for communication and in this study we investigated neural correlates of gesture perception in MDD. We hypothesised different neural activity between individuals with MDD and typical individuals when viewing instrumental and expressive gestures that were negatively or positively valenced. Differences
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Standardizing MRI orientation improves reliability of entorhinal and transentorhinal cortical volume measurement Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-18 Yi-En Quek, Yi Leng Fung, Simon J. Vogrin, Pierrick Bourgeat, Sara Vogrin, Jurgen Fripp, Steven J. Collins, Stephen C. Bowden
The current study compared the reliability of manual collateral sulcus depth and entorhinal and transentorhinal cortical volume measurements between native oriented MRI scans versus MRI scans realigned to the hippocampal long axis. Data included 10 participants with two serial 3.0T MRI scans from the Alzheimer's Disease Neuroimaging Initiative. Both collateral sulcus depth and entorhinal and transentorhinal
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Abnormal spontaneous activity of regions related to mood regulation mediates the effect of childhood emotional neglect on major depressive disorder Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-18 Suzhen Chen, Yingying Yin, Yuqun Zhang, Yingying Yue, Wenhao Jiang, Zhenghua Hou, Yonggui Yuan
This study investigated the mediating factors between childhood emotional neglect (EN) and major depressive disorder (MDD) and whether combining multi-indicator could help diagnose MDD. Regional homogeneity (ReHo) and clinical features were compared between 33 MDD patients and 36 healthy controls (HC). Mediation analysis was employed to explore whether social support or ReHo mediates the association
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Clinical efficacy of neurofeedback protocols in treatment of Attention Deficit/Hyperactivity Disorder (ADHD): A systematic review Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-11 Mohammed Gamil Mohammed Saif, Lyudmila Sushkova
Attention Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder of childhood and its effects mostly continue to adulthood. Neurofeedback training has shown promising results in the treatment of ADHD. However, there is no yet consensus as to the efficacy of neurofeedback in comparison to stimulant medication. Despite a large number of meta-analyses and comparative reviews on
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A meta-analysis of gray matter volume abnormalities in HIV patients Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-10-04 Mingxiang Xu, Xing-Da Ju
HIV infection is known to have significant effects on central nervous system. This study conducted a meta-analysis of whole voxel-based morphometry (VBM) in HIV patients (N = 435) and HIV-uninfected controls (N = 397). This study observed a reduction of limbic lobe, cingulate gyrus, frontal lobe, middle frontal gyrus, sub-lobar, insula, inferior frontal gyrus and superior frontal gyrus volume in HIV
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Regional cerebral blood flow at rest in schizophrenia and major depressive disorder: A functional neuroimaging meta-analysis Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-29 Mélanie Boisvert, Ovidiu Lungu, Florence Pilon, Alexandre Dumais, Stéphane Potvin
Severe mental disorders (SMDs) such as schizophrenia (SCZ), major depressive disorder (MDD) and bipolar disorder (BD) are associated with altered brain function. Neuroimaging studies have illustrated spontaneous activity alterations across SMDs, but no meta-analysis has directly compared resting-state regional cerebral blood flow (rCBF) with one another. We conducted a meta-analysis of PET, SPECT and
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Glutamatergic abnormalities in the pregenual anterior cingulate cortex in obsessive-compulsive disorder using magnetic resonance spectroscopy: A controlled study Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-28 Eliška Kosová, Dita Pajuelo, David Greguš, Martin Brunovský, Pavla Stopková, Iveta Fajnerová, Jiří Horáček
In this study, we utilized proton magnetic resonance spectroscopy (MRS) to understand the role of glutamate (Glu), glutamine (Gln), and gamma-aminobutyric acid (GABA) of OCD patients in the pregenual anterior cingulate cortex (pgACC). In total, 54 patients with OCD and 54 healthy controls (HC) matched for age and sex were included in the study. They underwent MRS in the pgACC region to calculate the
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Striatal and thalamic automatic segmentation, morphology, and clinical correlates in Parkinsonism: Parkinson's disease, multiple system atrophy and progressive supranuclear palsy Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-25 M. Erlinger, R. Molina-Ruiz, A. Brumby, D. Cordas, M. Hunter, C. Ferreiro Arguelles, M. Yus, C. Owens-Walton, D. Jakabek, M. Shaw, E. Lopez Valdes, J.C.L. Looi
Parkinson's disease (PD), multisystem atrophy (MSA), and progressive supranuclear palsy (PSP) present similarly with bradykinesia, tremor, rigidity, and cognitive impairments. Neuroimaging studies have found differential changes in the nigrostriatal pathway in these disorders, however whether the volume and shape of specific regions within this pathway can distinguish between atypical Parkinsonian
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Polygenic risk for neuroticism is associated with less efficient control in more difficult situations Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-14 Heekyeong Park, Katherine L. Forthman, Rayus Kuplicki, Teresa A. Victor, Hung-Wen Yeh, Wesley K. Thompson, Jonathon R. Howlett, Salvador Guinjoan, Martin P. Paulus
Neuroticism is a heritable trait and a risk factor for mental health due to its relevance to poor control of negative events. To examine the relationship between genetic propensity for neuroticism and control processing, we used the polygenic risk score (PRS) approach and a stop signal task during fMRI. We hypothesized that genetic propensity for neuroticism may moderate control processing as a function
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Targeting the insula with transcranial direct current stimulation; A simulation study Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-15 Negin Esmaeilzadeh Kiabani, Reza Kazemi, Abed L. Hadipour, Sanaz Khomami, Benjamin Kalloch, Mario Hlawitschka
Insula is considered an important region of the brain in the generation and maintenance of a wide range of psychiatric symptoms, possibly due to being key in fundamental functions such as interoception and cognition in general. Investigating the possibility of targeting this area using non-invasive brain stimulation techniques can open new possibilities to probe the normal and abnormal functioning
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The shape of things to come. Mapping spatiotemporal progression of striatal morphology in Huntington disease: The IMAGE-HD study Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-14 Fiona A. Wilkes, David Jakabek, Mark Walterfang, Dennis Velakoulis, Govinda R. Poudel, Julie C. Stout, Phyllis Chua, Gary F. Egan, Jeffrey C.L. Looi, Nellie Georgiou-Karistianis
Mapping the spatiotemporal progression of neuroanatomical change in Huntington's Disease (HD) is fundamental to the development of bio-measures for prognostication. Statistical shape analysis to measure the striatum has been performed in HD, however there have been a limited number of longitudinal studies. To address these limitations, we utilised the Spherical Harmonic Point Distribution Method (SPHARM-PDM)
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Birth season and gross brain morphology associated with early neurodevelopment in schizophrenia spectrum patients and healthy subjects Psychiatry Res. Neuroimaging (IF 2.3) Pub Date : 2023-09-06 Tsutomu Takahashi, Daiki Sasabayashi, Yoichiro Takayanagi, Haruko Kobayashi, Misako Torigoe, Kazumi Sakamoto, Yusuke Yuasa, Noa Tsujii, Kyo Noguchi, Michio Suzuki
This MRI study examined the effects of birth seasons on gross brain characteristics, such as the prevalence/size of midline brain structures (cavum septi pellucidi and adhesio interthalamica), orbitofrontal surface morphology, and insular gross anatomy, in 135 patients with schizophrenia, 47 with schizotypal disorder, and 88 healthy controls. Birth seasons only affected the insular anatomy. Summer-born