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Determinants of confrontation naming deficits on the Boston Naming Test associated with transactive response DNA-binding protein 43 pathology J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-03-25 Carling G. Robinson, Austin W. Goodrich, Stephen D. Weigand, Nha Trang Thu Pham, Arenn F. Carlos, Marina Buciuc, Melissa E. Murray, Aivi T. Nguyen, R. Ross Reichard, David S. Knopman, Ronald C. Petersen, Dennis W. Dickson, Rene L. Utianski, Jennifer L. Whitwell, Keith A. Josephs, Mary M. Machulda
Objective: To determine whether poorer performance on the Boston Naming Test (BNT) in individuals with transactive response DNA-binding protein 43 pathology (TDP-43+) is due to greater loss of word knowledge compared to retrieval-based deficits. Methods: Retrospective clinical-pathologic study of 282 participants with Alzheimer’s disease neuropathologic changes (ADNC) and known TDP-43 status. We evaluated
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Impact of age and apolipoprotein E ε4 status on regional white matter hyperintensity volume and cognition in healthy aging J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-03-22 Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Objective: White matter hyperintensity (WMH) volume is a neuroimaging marker of lesion load related to small vessel disease that has been associated with cognitive aging and Alzheimer’s disease (AD) risk. Method: The present study sought to examine whether regional WMH volume mediates the relationship between APOE ε4 status, a strong genetic risk factor for AD, and cognition and if this association
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Neurocognitive outcome and associated factors in long-term, adult survivors of childhood acute lymphoblastic leukemia, treated without cranial radiation therapy J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-03-11 Kaja Solland Egset, Jan Stubberud, Ellen Ruud, Magnus Aassved Hjort, Mary-Elizabeth Bradley Eilertsen, Anne Mari Sund, Odin Hjemdal, Siri Weider, Trude Reinfjell
Objective: There is limited research on neurocognitive outcome and associated risk factors in long-term, adult survivors of childhood acute lymphoblastic leukemia (ALL), without treatment of cranial radiation therapy. Moreover, the impact of fatigue severity and pain interference on neurocognition has received little attention. In this cross-sectional study, we examined neurocognitive outcome and associated
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Six elements test vs D-KEFS: what does “Ecological Validity” tell us? J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-03-11 Yana Suchy, Michelle Gereau Mora, Stacey Lipio Brothers, Libby A. DesRuisseaux
Objective: Extensive research shows that tests of executive functioning (EF) predict instrumental activities of daily living (IADLs) but are nevertheless often criticized for having poor ecological validity. The Modified Six Elements Test (MSET) is a pencil-and-paper test that was developed to mimic the demands of daily life, with the assumption that this would result in a more ecologically valid test
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Facilitating clinical use of the Amsterdam Instrumental Activities of Daily Living Questionnaire: Normative data and a diagnostic cutoff value J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-03-08 Merel C. Postema, Mark A. Dubbelman, Jürgen Claesen, Craig Ritchie, Merike Verrijp, Leonie Visser, Pieter-Jelle Visser, Marissa D. Zwan, Wiesje M. van der Flier, Sietske A.M. Sikkes
Objective: The Amsterdam Instrumental Activities of Daily Living Questionnaire (A-IADL-Q) is well validated and commonly used to assess difficulties in everyday functioning regarding dementia. To facilitate interpretation and clinical implementation across different European countries, we aim to provide normative data and a diagnostic cutoff for dementia. Methods: Cross-sectional data from Dutch Brain
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Robust reference group normative data for neuropsychological tests accounting for primary language use in Asian American older adults J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-03-01 Arunima Kapoor, Jean K. Ho, Jung Yun Jang, Daniel A. Nation
Objective: The present study aimed to develop neuropsychological norms for older Asian Americans with English as a primary or secondary language, using data from the National Alzheimer’s Coordinating Center (NACC). Method: A normative sample of Asian American participants was derived from the NACC database using robust criteria: participants were cognitively unimpaired at baseline (i.e., no MCI or
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Visual associative learning to detect early episodic memory deficits and distinguish Alzheimer’s disease from other types of dementia J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-02-23 Mark A. Dubbelman, Jori Tomassen, Sophie M. van der Landen, Els Bakker, Suzie Kamps, Annemartijn A.J.M. van Unnik, Marie-Christine A.B.J. van de Glind, Annelies E. van der Vlies, Ted Koene, Anna E. Leeuwis, Frederik Barkhof, Argonde C. van Harten, Charlotte Teunissen, Elsmarieke van de Giessen, Afina W. Lemstra, Yolande A.L. Pijnenburg, Rudolf W.H. Ponds, Sietske A.M. Sikkes
Objective: We investigated how well a visual associative learning task discriminates Alzheimer’s disease (AD) dementia from other types of dementia and how it relates to AD pathology. Methods: 3,599 patients (63.9 ± 8.9 years old, 41% female) from the Amsterdam Dementia Cohort completed two sets of the Visual Association Test (VAT) in a single test session and underwent magnetic resonance imaging.
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New insights on what leads bilinguals to be able to name some pictures only in their nondominant language: Immersion, dominance reversal, and balanced bilingualism J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-02-19 Anne Neveu, Tamar H. Gollan
Objective: The present study asked if bilinguals who are immersed in their nondominant language are more likely to know some words only in their nondominant language. Method: The either-language scoring benefit (ELSB) reflects how many more points bilinguals get when credited for pictures named regardless of which language is used. We asked if the ELSB varies with self-rated proficiency level of the
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Exploring symptom clusters in mild cognitive impairment and dementia with the NIH Toolbox J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-02-16 Callie E. Tyner, Aaron J. Boulton, Jerry Slotkin, Matthew L. Cohen, Sandra Weintraub, Richard C. Gershon, David S. Tulsky
Objective: Symptom clustering research provides a unique opportunity for understanding complex medical conditions. The objective of this study was to apply a variable-centered analytic approach to understand how symptoms may cluster together, within and across domains of functioning in mild cognitive impairment (MCI) and dementia, to better understand these conditions and potential etiological, prevention
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Development of robust normative data for the neuropsychological assessment of Greek older adults J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-29 Xanthi Arampatzi, Eleni S. Margioti, Lambros Messinis, Mary Yannakoulia, Georgios Hadjigeorgiou, Efthimios Dardiotis, Paraskevi Sakka, Nikolaos Scarmeas, Mary H. Kosmidis
Objective: Normative data for older adults may be tainted by inadvertent inclusion of undiagnosed individuals at the very early stage of a neurodegenerative process. To avoid this pitfall, we developed norms for a cohort of older adults without MCI/dementia at 3-year follow-up. Methods: A randomly selected sample of 1041 community-dwelling individuals (age ≥ 65) received a full neurological and neuropsychological
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Naturalistic assessment of reaction time variability in older adults at risk for Alzheimer’s disease J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-29 Matthew S. Welhaf, Hannah Wilks, Andrew J. Aschenbrenner, David A. Balota, Suzanne E. Schindler, Tammie L.S. Benzinger, Brian A. Gordon, Carlos Cruchaga, Chengjie Xiong, John C. Morris, Jason Hassenstab
Objective: Maintaining attention underlies many aspects of cognition and becomes compromised early in neurodegenerative diseases like Alzheimer’s disease (AD). The consistency of maintaining attention can be measured with reaction time (RT) variability. Previous work has focused on measuring such fluctuations during in-clinic testing, but recent developments in remote, smartphone-based cognitive assessments
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Premorbid personality traits as predictors for incident predementia syndromes: a multistate model approach J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-29 Morgan J. Schaeffer, Stuart W.S. MacDonald, Theone S.E. Paterson
Objective: Associations have been found between five-factor model (FFM) personality traits and risk of developing specific predementia syndromes such as subjective cognitive decline (SCD) and mild cognitive impairment (MCI). The aims of this study were to: 1) Compare baseline FFM traits between participants who transitioned from healthy cognition or SCD to amnestic MCI (aMCI) versus non-amnestic MCI
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The association between symptom burden and processing speed and executive functioning at 4 and 12 weeks following pediatric concussion J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-26 Veronik Sicard, Andrée-Anne Ledoux, Ken Tang, Keith Owen Yeates, Brian L. Brooks, Peter Anderson, Michelle Keightley, Naddley Desire, Miriam H. Beauchamp, Roger Zemek, for the Pediatric Emergency Research Canada (PERC) 5P Neuropsych team
Objectives: Symptoms and cognition are both utilized as indicators of recovery following pediatric concussion, yet their interrelationship is not well understood. This study aimed to investigate: 1) the association of post-concussion symptom burden and cognitive outcomes (processing speed and executive functioning [EF]) at 4 and 12 weeks after pediatric concussion, and 2) the moderating effect of sex
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Conceptualization of the term “ecological validity” in neuropsychological research on executive function assessment: a systematic review and call to action J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-25 Yana Suchy, Libby A. DesRuisseaux, Michelle Gereau Mora, Stacey Lipio Brothers, Madison A. Niermeyer
Objective: “Ecological validity” (EV) is classically defined as test’s ability to predict real-world functioning, either alone or together with test’s similarity to real-world tasks. In neuropsychological literature on assessment of executive functions (EF), EV is conceptualized inconsistently, leading to misconceptions about the utility of tests. The goal of this systematic review was to examine how
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Comparing neuropsychological, typical, and ADNI criteria for the diagnosis of mild cognitive impairment in Vietnam-era veterans J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-24 Monica T. Ly, Jennifer Adler, Adan F. Ton Loy, Emily C. Edmonds, Mark W. Bondi, Lisa Delano-Wood, for the Department of Defense Alzheimer’s Disease Neuroimaging Initiative
Objective: Neuropsychological criteria for mild cognitive impairment (MCI) more accurately predict progression to Alzheimer’s disease (AD) and are more strongly associated with AD biomarkers and neuroimaging profiles than ADNI criteria. However, research to date has been conducted in relatively healthy samples with few comorbidities. Given that history of traumatic brain injury (TBI) and post-traumatic
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Discrepancies between self- and informant-ratings of functional abilities and objective cognition: predictors of bias in mild cognitive impairment J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-24 Liselotte De Wit, Felicia C. Goldstein, Jessica L. Saurman, Amy D. Rodriguez, Kayci L. Vickers
Objective: Self- and informant-ratings of functional abilities are used to diagnose mild cognitive impairment (MCI) and are commonly measured in clinical trials. Ratings are assumed to be accurate, yet they are subject to biases. Biases in self-ratings have been found in individuals with dementia who are older and more depressed and in caregivers with higher distress, burden, and education. This study
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Psychometric reliability, validity, and generalizability of 3MSE scores among American Indian adults: the Strong Heart Study J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-24 Astrid M. Suchy-Dicey, Thao T. Vo, Kyra Oziel, Dedra S. Buchwald, Lonnie A. Nelson, Steven P. Verney, Brian F. French
Objective: Modified Mini-Mental State Examination (3MSE) is often used to screen for dementia, but little is known about psychometric validity in American Indians. Methods: We recruited 818 American Indians aged 65–95 for 3MSE examinations in 2010–2013; 403 returned for a repeat examination in 2017–2019. Analyses included standard psychometrics inferences for interpretation, generalizability, and extrapolation:
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The effect of age on executive functions in adults is not sex specific J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-15 Marilou Lemire, Isabelle Soulières, Dave Saint-Amour
Objective: Numerous studies have shown a decrease in executive functions (EF) associated with aging. However, few investigations examined whether this decrease is similar between sexes throughout adulthood. The present study investigated if age-related decline in EF differs between men and women from early to late adulthood. Methods: A total of 302 participants (181 women) aged between 18 and 78 years
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Metamemory and executive function mediate the age-related decline in memory J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-15 Michael K. Yeung
Objective: Although the effect of aging on episodic memory is relatively well studied, little is known about how aging influences metamemory. In addition, while executive function (EF) is known to mediate the age-related decline in episodic memory, the role of metamemory in aging-related memory differences beyond EF remains unknown. This study aimed to elucidate the effect of aging on metamemory and
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Moving on with (social) cognition in idiopathic cervical dystonia J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2024-01-15 Maraike A. Coenen, Jacoba M. Spikman, Marenka Smit, Jesper Klooster, Marina A.J. Tijssen, Marleen J.J. Gerritsen
Objective: Cervical dystonia (CD) is a movement disorder characterized by involuntary muscle contractions causing sustained twisting movements and abnormal postures of the neck and head. Assumed affected neuronal regions are the cortico-striatal-thalamo-cortical circuits, which are also involved in cognitive functioning. Indeed, impairments in different cognitive domains have been found in CD patients
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74 The Impact of Motoric Dysfunction on Neuropsychological Test Performance Within an Electrical Injury Sample J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Maximillian A Obolsky, Humza Khan, Zachary J Resch, Jessica L Paxton, Jason R Soble, Joseph W Fink, Neil H Pliskin
Objective:Victims of electrical injury (EI) often experience injuries to the peripheral nervous system and neuromuscular damage that may diminish motor function, such as flexibility/dexterity. These difficulties may continue after rehabilitation due to the reorganization of muscle afferent projections during peripheral nerve regeneration. Therefore, understanding how patients with a history of thermal
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1 Sluggish Cognitive Tempo in Children and Adolescents with Fetal Alcohol Spectrum Disorders: Associations with Executive Function and Subcortical Volumes J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Abigail M Ernst, Blake A Gimbel, Mary E Anthony, Donovan J Roediger, Erik de Water, Bryon A Mueller, Sarah N Mattson, Kelvin O Lim, Jeffrey R Wozniak
Objective:Fetal alcohol spectrum disorder (FASD) is a common neurodevelopmental condition associated with deficits in cognitive functioning (executive functioning [EF], attention, working memory, etc.), behavioral impairments, and abnormalities in brain structure including cortical and subcortical volumes. Rates of comorbid attention-deficit/hyperactivity disorder (ADHD) are high in children with FASD
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43 Transcutaneous Vagus Nerve Stimulation Effects on Functional Connectivity of the Hippocampus in Mild Cognitive Impairment J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Alexandria G O'Neal, Ronald Cohen, Eric C Porges, Damon G Lamb, Aidan Murphy, Steven T DeKosky, John B Williamson
Objective:Transcutaneous vagus nerve stimulation (tVNS) is a promising potential intervention for Alzheimer's disease (AD) due to its influence on brain functions and mechanisms important in disease progression. Regions of interest include projection to the nucleus of the solitary tract, locus coeruleus, and hippocampus. Deterioration of the hippocampus is one of the most prominent early characteristics
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11 Social Determinants of Health in Pediatric Brain Tumor Survivors: Associations between Neighborhood Opportunity and Neurocognitive and Psychological Outcomes J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Johanna Nielsen, Christina Sharkey, Kristina Hardy, Karin Walsh
Objective:A growing body of research demonstrates that social determinants of health (SDOH) are important predictors of neurocognitive and psychological outcomes in survivors of pediatric brain tumor (PBT). Existing research has focused primarily on individual level SDOH (e.g., family income, education, insurance status). Thus, more information is needed to understand community level factors which
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CE Workshop 03: Stroke in the Developing Brain: Mechanisms, Outcomes, and Intervention J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Robyn Westmacott
& Learning Objectives:Over the past 10-15 years, significant progress has been made in the diagnosis and treatment of pediatrics stroke. Accordingly, the focus of much research has turned to understanding factors that determine neurological and neuropsychological outcomes in this population. This Continuing Education (CE) course will start by defining key terms in the field of pediatric stroke and
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25 The Hybrid Learning Environment During Covid-19: A Case Study on IEP Implementation for a Student with Autism Spectrum Disorder J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Stephanie Hernandez, Lisa Bendixen, Sharlene Jeffers
Objective:An effective support system for families with children with an Autism Spectrum Disorder (ASD) consists of multiple methods of educational and therapeutic delivery. Such methods are adapted to meet a family’s needs and needs of the time, like the COVID-19 pandemic. Individualized Educational Plan (IEP) are established by schools to support success in academics for children with ASD. IEPs can
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17 Norming for the reverse-translated 5-choice continuous performance test (5C-CPT) of attention and cognitive control J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Michael Noback, Donald R Franklin, Anya Umlauf, Arpi Minassian, Robert Heaton, Jared W Young
Objective:Translatability of preclinical results remains a major obstacle in neuropsychiatric research. Even when cognitive tests in preclinical models show translational validity for human testing, with sensitivity to clinical deficits, there remains the issue of heterogeneity among human participants. Norming of performance on cognitive tasks enable corrections for any differences in performance
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5 The impact of recreational cannabis use on neuropsychological function in epilepsy J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Lucy Roberts-West, Sallie Baxendale
Objective:Cannabis is classified as a class B drug in the UK with penalties for possession of up to 5 years in prison, an unlimited fine or both. Nevertheless it is widely available and is the most commonly used drug in the UK with approximately 2.6 million (7.6%) of adults reporting that they sometimes or regularly use it. It is not uncommon for people who present in our epilepsy clinic to report
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25 Associations between Diffusion Kurtosis Imaging, Tau, and Cognitive Outcomes in TBI J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Robert D Claar, Aditi Venkatesh, Richard Rubenstein, Kevin Wang, Amy Wagner, Claudia Robertson, Erin Trifilio, John Williamson, Damon Lamb
Objective:Determine associations between cognitive outcomes in remote TBI (i.e., at least 6 months post injury), a blood marker of neural degeneration (i.e., Tau), and diffusion kurtosis imaging (DKI) measures (e.g., mean or radial kurtosis). Because DKI imaging is sensitive to the environmental complexity of the imaged area, we sought to investigate regions known to be associated with the cognitive
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6 Code-switching, Language Attitudes, and Executive Function in Latinx Bilinguals J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Alice Gavarrete Olvera, Jet M. J. Vonk, Adam M. Brickman, Desiree Byrd, Miguel Arce Renteria
Objective:Code-switching is when bilingual individuals alternate between two languages in the same conversation. Some studies find that code-switching frequency is associated with executive functioning, while others do not. Individual attitudes towards bilingual language use and code-switching may explain the inconsistency in the literature. For instance, greater positive attitudes towards code-switching
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CE Workshop 07: Cognitive Effects of Cancer and Treatment: “Chemobrain” and Beyond J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Brenna C. McDonald
& Learning Objectives:Improvements in treatment for non-CNS cancer have greatly improved survivorship, allowing increased attention to cancer- and treatment-related sequelae. Cognitive symptoms (cancer-related cognitive impairment, or CRCI) are reported by a large percentage of cancer survivors, and can have a clinically meaningful impact on educational, vocational, and social functioning, and thus
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Poster Symposium: How Well do Western Methods Used to Assess Atypical Aging in Western Countries Generalize to Sub-Saharan African Countries? J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Suzanne Penna, Jean Ikanga
Summary Abstract:Risk factors associated with development of neurodegenerative disease has been well-studied in Western and European populations. However, there has been considerably less research in the assessment of such risk factors in developing countries, notably sub-Saharan Africa. There is a paucity of data at the micro level (e.g. neuroimaging and biomarker data) and macro level (e.g. cognitive
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82 Single Errors on Trial 1 of the Test of Memory Malingering may be Indicative of Invalid Performance on Neuropsychological Measures in a Sample of Youth Athletes J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Daniel Baldini, Talamahe’a A. Tupou, Julius Flowers, Ashlynn Steinbaugh, Bradley R. Forbes, Michael Ellis-Stockley, Rachel Murley, Rayna B. Hirst
Objective:The Test of Memory Malingering (TOMM) is a performance validity test (PVT) that aims to assess whether participants are giving adequate effort to perform well on tasks of memory performance (Tombaugh, 1996). Other PVTs, specifically the Forced Choice Recognition Trial in the California Verbal Learning Test, have shown that even single errors may indicate invalid performance (Erdodi et al
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Invited Symposium 2: The Need for a Highly Individualized Approach to Brain Mapping: Neuroanatomical, Lifespan and Cultural-Language Considerations J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 David S. Sabsevitz, Madison Berl, Połczyńska Monika
& Learning Objectives:Brain mapping is critical in reducing risk for cognitive morbidity in epilepsy and brain tumor surgery. Mapping using functional MRI, and extra- and intraoperative electrical stimulation, requires a high level of expertise in functional neuroanatomy but also an understanding of individual patient characteristics that can impact mapping results and post-operative outcome. Patients
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9 The Correlation of IQ and Executive Function of VLBW and ELBW Preterm Children with Normal Early Development J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Ni Tzu-Lo, Chao-Ching Huang, Nai-Wen Guo
Objective:Previous studies had shown that even with normal early development, preterm children at age six still have executive function deficits, including planning, cognitive flexibility, and nonverbal working memory. The present study aims to discuss further the correlation between IQ and EF of preterm children with different birthweight in order to clarify the potential influence of birthweight
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24 Associations Between Positive Psychological Factors and Neurocognitive Functioning in Older Adults J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Jacqueline E Maye, Colin A Depp, Ellen E Lee, Ho-Cheol Kim, Dilip V Jeste, Elizabeth W Twamley
Objective:Psychological wellness and strong cognitive skills are both important to successful aging. Although there are well-established relationships between psychiatric illness (e.g., depression, anxiety, PTSD) and cognitive dysfunction, few studies have focused on the relationships between positive psychological factors and neurocognitive function in older adults. Our goal was to explore associations
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6 Trauma Exposure as a Predictor for Score Profiles on Structured and Unstructured Tasks of Verbal Memory in a Community Sample J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Halima Hussaini, Hannah VanLandingham, Madeline Sadoff, Kush Patil, Jay Rosen, Allison Kaup, Lori Haase Alasantro
Objective:Evidence suggests that the most consistent cognitive impairment found in individuals experiencing posttraumatic stress disorder symptomology is verbal memory impairment (Johnsen & Asbjornsen, 2008). More specifically, research has shown that patients with PTSD perform poorer on verbal memory tasks relating to logical (story) memory than on word memory tasks, such as CVLT-III (Barrera-Valencia
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11 NASA-TLX Workload Profile of the Trail Making Test J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 David J. Hardy, Hannah A. Agbaroji, Oliver J. Hatch, Estefania Valencia, David J. Moore, Matthew J. Wright
Objective:Workload is a useful construct in human factors and neuroergonomics research that describes “the perceived relationship between the amount of mental [and physical] processing capability or resources and the amount required by the task”. We apply this concept to neuropsychology and assess several dimensions of workload as it relates to performance on the Trail Making Test.Participants and
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74 Neurobehavioral Symptoms of Dementia as a Risk Factor for Poor Caregiver Sleep Quality J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Rylea M Ranum, Andrew M Kiselica, Kimberly O’Leary
Objective:Caregivers to persons with dementia (PWD) consistently report lower sleep quality than non-caregiving controls. Low sleep quality, in addition to being unhealthy for the caregiver, may also impact the quality of care provided to the PWD. One factor that may contribute to poor sleep among caregivers is neurobehavioral symptoms (NBS) of the PWD. NBS, such as mood changes, lack of motivation
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56 Predictors of Finger Tapping Variability in Older Adults Evaluated for a Neurodegenerative Memory Disorder J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Molly M McElvogue, Lori Steffes, Anna Burke, Ashley M Stokes, George P Prigatano
Objective:Patients with early Alzheimer Disease (AD) and Mild Cognitive Impairment of the Amnestic type (MCI-A) have been reported to show large variability of tapping scores. Factors that contribute to that variability remain undetermined. This preliminary study aimed to identify predictors of finger tapping variability in older adults evaluated for a neurodegenerative memory disorder. Based on earlier
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86 The Examination Between Credible and Non-Credible Groups on Embedded PVT Tests J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Krissy E. Smith, Tara L. Victor, Matthew J. Wright, Kyle B. Boone, Daniel W. Lopez-Hernandez
Objective:Performance validity tests (PVTs) are included in neuropsychological testing to ensure examinees are performing to the best of their abilities. There are two types of PVTs: embedded and free standing. Embedded PVTs are tests that are derived from standard neuropsychological tests of various cognitive domains. Freestanding PVTs are tests that are designed with the intention of being a PVT
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13 Regional White Matter Hyperintensities are Associated with Cognition in Prospective Alzheimer’s Clinical Trial Participants J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Clarissa D. Morales, Dejania Cotton-Samuel, Kay C. Igwe, Patrick J. Lao, Julia F. Chang, Amirreza Sedaghat, Mohamad J. Alshikho, Rafael Lippert, Kelsang C. Bista, Kacie Deters, Molly E. Zimmerman, Adam M. Brickman
Objective:Previous research established that white matter hyperintensities (WMH), a biomarker of small vessel cerebrovascular disease, are strong predictors of cognitive function in older adults and associated with clinical presentation of Alzheimer’s disease (AD), particularly when distributed in posterior brain regions. Secondary prevention clinical trials, such as the Anti-Amyloid Treatment in Asymptomatic
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59 A Preliminary Investigation of Digital Clock Drawing in Fibromyalgia Patients Versus Non-Fibromyalgia Peers J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Yonah Joffe, Catherine Dion, Emily F Matusz, Shawna Amini, Patrick J Tighe, Michael E Robinson, Catherine Price
Objective:Widespread musculoskeletal pain disorders like fibromyalgia are often accompanied by varying levels of cognitive dysfunction. Fibromyalgia research suggests that around the time of diagnosis, typically 30-50 years of age, many patients are already showing cognitive difficulties on various neuropsychological assessments. It is unknown, however, how older adults with fibromyalgia perform on
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5 Anticholinergic Medications, Cognition, and Parkinson’s Disease. Do Medications matter? J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Lauren G Santos, Lauren E Kenney, Alyssa Ray, Alfredo A Paredes, Adrianna M Ratajska, Dawn Bowers
Objective:While Parkinson’s disease (PD) is traditionally known as a movement disorder, cognitive decline is one of the most debilitating and common non-motor symptoms. Cognitive profiles of individuals with PD are notably heterogeneous (Goldman et al., 2018). While this variability may arise from the disease itself, other factors might play a role. Greater anticholinergic medication use has been linked
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6 Exercise Induced Growth Factor Increases Directly and Indirectly Reduce Systemic Vascular Risk Parameters: Translational Project Amongst Midlife Human and Animal Models of Preclinical Alzheimer’s disease and Vascular Dementia J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Amanda Hewes, Kate Foley, Jennifer Thompson, Lindsey Lagerstrom, Taylor Mcmillan, Gareth Howell, Fayeza Ahmed
Objective:Using a humanized APOE3/4 (Alzheimer’s disease genetic risk allele) mouse model we investigated the potential modulating effects of exercise on systemic risk factors and the ability of this mouse model to translate to active or sedentary, midlife, human participants. We present preliminary results of an ongoing, translational pilot study.Participants and Methods:26 Midlife individuals, ages
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44 Can Clinical Trial data Inform our Understanding of the role of Depressive Symptoms in Alzheimer's Disease? J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Munira Z Urmi, Dejania Cotton-Samuel, Clarissa D Morales, Kay C Igwe, Julia F Chang, Amirreza Sedaghat, Patrick J Lao, Rafael V Lippert, Adam M Brickman
Objective:Neuropsychiatric symptoms concerning mood are common in Alzheimer's disease (AD), but it is unclear if they are etiologically related to AD pathophysiology or due to factors considered to be non-pathogenic, such as small vessel cerebrovascular disease. New generation clinical trials for AD often enroll participants with evidence of AD pathophysiology, indexed by amyloid PET scanning, but
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70 Uncovering Comorbid Neuropsychological Disorders in Children with Unilateral Hearing Loss Under Consideration for Cochlear Implantation J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Rachel Landsman, Amanda Griffin, Matthew Fasano-McCarron, David Faller, Margaret Kenna, Greg Licameli, Peter Isquith
Objective:Children with unilateral hearing loss (UHL) have difficulty hearing in noisy environments and localizing sounds, impacting learning and social opportunities across contexts. Using a visible device like a cochlear implant (CI) may improve functioning but can also create psychological risk. Audiological measures alone are insufficient for predicting social, emotional, educational, adaptive
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5 Social perception and ability to evaluate sincerity of speech impacted by childhood hemispherectomy J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Mitchell R Spezzaferri, Lynn K Paul, Warren S Brown
Objective:Hemispherectomy (HE) is a surgical intervention to treat intractable epilepsy. It involves disconnecting or removing the right or left cerebral hemisphere, depending on the location of the pathological substrate or epileptogenic activity. HE impacts neural functions related to social cognition (Fournier et al., 2008). This study investigates the effects of childhood HE on social deception
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2 Cognitive Processing Speed Training in Individuals with Multiple Sclerosis J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 John DeLuca, Nancy Chiaravalloti, Silvana Costa, Nancy Moore
Objective:Cognitive impairment is observed in up to two-thirds of persons with Multiple Sclerosis (MS). Impairments in cognitive processing speed (PS) is the most prevalent cognitive disturbance, occurs early in the course of disease and is strongly associated with disease progression, various brain parameters and everyday life functional activities. As such, cognitive rehabilitation for PS impairments
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3 The Relationship Between Depression, Anxiety, and Autonomic Dysfunction in de novo Parkinson’s Disease Patients Over Time J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Adrianna M. Ratajska, Francesca V. Lopez, Lauren E. Kenney, Katie Rodriguez, Rachel Schade, Joshua Gertler, Dawn Bowers
Objective:Autonomic dysfunction is an important non-motor symptom of Parkinson’s disease (PD), with point prevalence estimates of approximately 50-70%. Common presentations include cardiovascular dysregulation, gastrointestinal dysfunction, impaired thermoregulation, and sexual dysfunction. In the present study, we sought to examine whether autonomic symptoms would predict trajectories of change in
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80 The Association between Periodontal Disease and Self-Reported Cognitive and Functional Decline at Age 60 in a Large, Multicultural Cohort Study J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Jessie Himmelstern, John R Warren, Eric Grodsky, Chandra Muller, Emily Lybbert, Adam Brickman, Jennifer Manly, Ryan Demmer
Objective:We assess the association between self-reported history of periodontal disease diagnosis with self-reported cognitive and functional decline at age ∼60. We also investigate (1) the roles of social background, demographic characteristics, education, and adolescent test scores in confounding that association and (2) the role of cardiovascular disease in mediating that association.Participants
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73 Sex and Race/Ethnicity in Reporting of Lingering Concussion Symptoms by Adolescents J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Stephen C Bunt, Nyaz Didehbani, Cheryl H Silver, Linda S Hynan, Hannah E Wadsworth, Hudaisa Fatima, Cason Hicks, Mathew Stokes, Shane M Miller, Kathleen Bell, C M Cullum
Objective:Consideration of individual differences in recovery after concussion has become a focus of concussion research. Sex and racial/ethnic identity as they may affect reporting of concussion symptoms have been studied at single time points but not over time. Our objective was to investigate the factors of self-defined sex and race/ethnicity in reporting of lingering concussion symptoms in a large
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45 The Influence of Wearing Face Mask on Facial Emotion Recognition in Preschoolers J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 June-Hui Huang, Nai-Wen Guo
Objective:During the COVID-19 pandemic, wearing face masks is an important strategy to prevent people from infection, allowing people to find a balance between maintaining social interaction and keeping social distancing. Since face mask might disrupt information processing of social cognition, it could lead to less functional connectivity of occipital face area, fusiform face area, and superior temporal
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28 Neurocognitive profile of pediatric acquired demyelinating syndrome with and without myelin oligodendrocyte glycoprotein antibody disease (MOGAD) J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Camille S. Wilson, Eric Nelson, Whit Mattson, H. Gerry Taylor, Melissa Hutchinson
Objective:Pediatric acquired demyelinating syndromes (PADS) include a heterogeneous group of diagnoses, including acute disseminated encephalomyelitis (ADEM), neuromyelitis optica spectrum disorders (NMOSD), optic neuritis (ON) and transverse myelitis (TM). Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is often associated with demyelinating conditions, but may also present with encephalopathy
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22 Cordoba Naming Test Performance and Acculturation in a Geriatric Population J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Isabel C.D. Muñoz, Krissy E. Smith, Santiago I. Espinoza, Diana M. R. Maqueda, Adriana C. Cuello, Ana Paula Pena, Carolina Garza, Raymundo Cervantes, Jill Razani, Tara L. Victor, David J. Hardy, Alberto L. Fernandez, Natalia Lozano Acosta, Daniel W. Lopez-Hernandez
Objective:A commonly used confrontation naming task used in the United States is The Boston Naming Test (BNT). Performance differences has been found in Caucasian and ethnic minorities on the BNT. The Cordoba Naming Test (CNT) is a 30-item confrontation naming task developed in Argentina. Past research has shown acculturation levels can influence cognitive performance. Furthermore, one study evaluated
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38 Craft Story 21, Argentine Baremization of a Memory test and Design of a Recognition Instance. J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Maria Agostina Carello, Nicolas Corvalän, Greta Keller, Micaela Maria Arruabarrena, Cecilia Palermo, Carlos Alberto Martinez Canyazo, Ismael Luis Calandri, Ricardo Francisco Allegri, Lucia Crivelli
Objective:Craft Story 21 is a practical, comprehensive, and freely available tool to assess logical memory in patients with memory impairment. Currently, the test does not have normative values in Spanish that adjust to our specific population. Furthermore, the original test does not have a recognition phase to increase the specificity of the memory profile by allowing a distinction between different
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6 Improved verbal fluency following unilateral right hemisphere subthalamic nucleus deep brain stimulation for Parkinson’s disease: Is implant hemisphere a modifiable risk factor for cognitive decline? J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Victor A Del Bene, Roy C Martin, Sarah A Brinkerhoff, Joseph W Olson, Dario Marotta, Christopher L Gonzalez, Kelly A Mills, J Nicole Bentley, Barton L Guthrie, Harrison C Walker
Objective:Non-motor symptoms, such as mild cognitive impairment and dementia, are an overwhelming cause of disability in Parkinson’s disease (PD). While subthalamic nucleus deep brain stimulation (STN DBS) is safe and effective for motor symptoms, declines in verbal fluency after bilateral DBS surgery have been widely replicated. However, little is known about cognitive outcomes following unilateral
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52 Differences in Neuropsychological Test Performance and Symptom Data in Schizophrenia with Co-Occurring Cannabis Use J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Jessica J Woodyatt, Grace J Goodwin, Bern G. Lee, Yuan Rairata, Gia Calip, Daniel N Allen
Objective:Long-term exposure to the psychoactive ingredient in cannabis, delta-9-tetrahydrocanabinol (THC), has been consistently raised as a notable risk factor for schizophrenia. Additionally, cannabis is frequently used as a coping mechanism for individuals diagnosed with schizophrenia. Cannabis use in schizophrenia has been associated with greater severity of psychotic symptoms, non-compliance
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83 WISC-V Profiles in a Pediatric Sickle Cell Disease Population J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Rebecca Avila-Rieger, Bryan Freilich, Nicole Feirsen, Jodi Uderman
Objective:Individuals with sickle cell disease (SCD) are at increased risk for developing impairment across cognitive domains, although the most common deficits are thought to be related to processing speed and executive functions. One of the most common ways of evaluating cognitive functioning is through the administration of intellectual tests. While lower overall intellectual functioning in individuals
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28 Challenges to Lateralizing Visual Memory Dysfunction in TLE Patients J. Int. Neuropsychol. Soc. (IF 2.6) Pub Date : 2023-12-22 Chantal Muller-Cohn, Carrie McDonald, Amanda Gooding, Marc Norman
Objective:Neuropsychological assessment is an essential part of presurgical evaluation for epilepsy patients with refractory temporal lobe epilepsy. Evaluations assist in localizing and lateralizing epileptogenic focal points and identifying possible risks for cognitive decline following surgery. Researchers and clinicians consistently find that verbal memory dysfunction is an accurate indicator of