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The thalamic clustering coefficient moderates the vigor–sleep quality relationship

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A Correction to this article was published on 12 July 2023

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Abstract

Sleep disorders affect more than one-quarter of the world's population, resulting in reduced daytime productivity, impaired immune function, and an increased risk of cardiovascular disease. It is important to identify the physiological and psychological factors related to sleep for the prevention and treatment of sleep disorders. In this study, we correlated measurements of emotional state, sleep quality, and some brain neural activity parameters to better understand the brain and psychological factors related to sleep. Resting-state functional magnetic resonance imaging (rs-fMRI) of 116 healthy undergraduates were analyzed using graph theory to assess regional topological characteristics. Among these, the left thalamic cluster coefficient proved to be the ablest to reflect the characteristics of the sleep neural graph index. The Profile of Mood States (POMS) was used to measure vigor, and the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality. The results showed that the left thalamic clustering coefficient was negatively correlated with sleep quality and vigor. Further, the left thalamic clustering coefficient moderated the relationship between vigor and sleep quality. When the left thalamic clustering coefficient was very low, there was a significant positive correlation between vigor and sleep quality. However, when the left thalamic clustering coefficient was high, the correlation between vigor and sleep quality became insignificant. The relationship between vigor and sleep quality is heterogeneous. Analyzing the function of the left thalamic neural network could help understand the variation in the relationship between vigor and sleep quality in different populations. Such observations may help in the development of personalized interventions for sleep disorders.

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Acknowledgements

We thank all students who participated in this research.

Funding

This research was supported by funding from the Youth Foundation for Humanities and Social Sciences Research of the Ministry of Education (21YJC190004). The study does not necessarily reflect the opinions or views of the funding sources. The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

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Authors and Affiliations

  1. College of Psychology, Liaoning Normal University, Dalian, 116029, China

    Xiaoqian Ding & Qingmin Li

  2. College of Health Solutions, Arizona State University, Tempe, AZ, 85281, USA

    Yi-Yuan Tang

  3. College of Health Solutions, Arizona State University, Phoenix, AZ, 85004, USA

    Yi-Yuan Tang

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  1. Xiaoqian Ding
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  2. Qingmin Li
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Ding, X., Li, Q. & Tang, YY. The thalamic clustering coefficient moderates the vigor–sleep quality relationship. Sleep Biol. Rhythms 21, 369–375 (2023). https://doi.org/10.1007/s41105-023-00456-2

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