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Electroconductive Materials Based on Polylactide and Polypyrrole for Biomedical Applications

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Abstract

Electroconductive scaffolds of different shape for tissue engineering have been obtained on the basis of two biocompatible polymers: polylactide and polypyrrole. The composite scaffolds have been based on porous permeable films or tubes of polylactides prepared via electrospinning. A layer of electroconductive polypyrrole has been applied at the developed surface of the scaffolds consisting of the chaotically interwoven fibers of micron-scale thickness. The structure of the tissue engineering scaffolds as well as their mechanical, redox, and electroconductive properties have been investigated. It has been found that the scaffolds are stable during electrical stimulation via prolonged application of the cyclic potentials.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, 199004, St. Petersburg, Russia

    I. Yu. Sapurina, M. A. Shishov, E. M. Ivan’kova & V. E. Yudin

  2. Peter the Great St. Petersburg Polytechnic University, 195251, St. Petersburg, Russia

    N. A. Zavrazhnykh, M. A. Shishov, E. M. Ivan’kova & V. E. Yudin

  3. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation, 194044, St. Petersburg, Russia

    V. P. Orlov

Authors
  1. N. A. Zavrazhnykh
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  2. I. Yu. Sapurina
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  3. M. A. Shishov
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  4. E. M. Ivan’kova
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  5. V. P. Orlov
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  6. V. E. Yudin
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Correspondence to I. Yu. Sapurina.

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Translated by E. Karpushkin

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Zavrazhnykh, N.A., Sapurina, I.Y., Shishov, M.A. et al. Electroconductive Materials Based on Polylactide and Polypyrrole for Biomedical Applications. Polym. Sci. Ser. A 65, 264–273 (2023). https://doi.org/10.1134/S0965545X23700943

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  • DOI: https://doi.org/10.1134/S0965545X23700943

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