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Current Alzheimer Research

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Perturbations in Microbiota Composition as a Novel Mediator in Neuropsychiatric, Neurological and Mental Disorders: Preventive and Therapeutic Complementary Therapies to Balance the Change

Author(s): Majid Taati Moghadam, Andrés Alexis Ramírez-Coronel, Samaneh Darijani, Majid Reza Akbarizadeh, Mahin Naderifar, Simin Soltaninejad, Shahla Shahbazi, Amin Sadeghi Dousari, Ali Mojtahedi* and Reza Akhavan-Sigari

Volume 20, Issue 4, 2023

Published on: 01 August, 2023

Page: [213 - 223] Pages: 11

DOI: 10.2174/1567205020666230718160914

Price: $65

Abstract

Although microbiology and neurology are separate disciplines, they are linked to some infectious and neurological diseases. Today, microbiome is considered as one of the biomarkers of health by many researchers. This has led to the association of microbiome changes with many neurological diseases. The natural microbiota has many beneficial properties. If disrupted and altered, it can lead to irreversible complications and many neurological diseases. Therefore, according to previous studies, some preventive and therapeutic complementary therapies can prevent or restore microbiome dysbiosis and inflammation in the nervous system. With our current perception of the microbiological basis for different neurological disorders, both aspects of drug treatment and control of perturbations of the microbiome should be considered, and targeting them simultaneously will likely help to attain favorable results.

Keywords: Microbiome, neurological disorders, antibiotic therapy, probiotics, fecal microbiota transplant, mental disorders.

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